id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-010018-gl8uuqej	Del Borrello, Giovanni	New insights into pediatric community‐acquired pneumonia gained from untargeted metabolomics: A preliminary study	2019-12-10		.txt	text/plain	2357	132	35	3, 4 Although epidemiological research has repeatedly pointed out that the large majority of lower respiratory infection in pediatric patients are caused by viruses, 2 physicians often lack the tools to reliably discriminate between bacterial and viral etiology [5] [6] [7] and a large percentage of children presenting with respiratory symptoms and fever are ultimately administered antibiotics. To increase the specificity of our findings and reduce the role of confounding variables, three exclusion criteria were strictly applied, concerning: infants (ie, children under 1 year of age), to avoid any diagnostic overlap between pneumonia and bronchiolitis; children with a previous diagnosis of chronic disease (HIV, asthma, immunodeficiency, CHD), to reduce the pathophysiological heterogeneity between CAP cases; and children given any oral or injected antibiotic therapy in the 48 hours preceding enrollment, to avoid cases of partially treated pneumonia, as the related pathophysiological profile differs from that of a lung infection devoid of any treatment.	./cache/cord-010018-gl8uuqej.txt	./txt/cord-010018-gl8uuqej.txt