id	sid	tid	token	lemma	pos
cord-310847-63gh2tg4	1	1	key	key	JJ
cord-310847-63gh2tg4	1	2	:	:	:
cord-310847-63gh2tg4	1	3	cord-310847	cord-310847	NNP
cord-310847-63gh2tg4	1	4	-	-	HYPH
cord-310847-63gh2tg4	1	5	63gh2tg4	63gh2tg4	CD
cord-310847-63gh2tg4	1	6	authors	author	NNS
cord-310847-63gh2tg4	1	7	:	:	:
cord-310847-63gh2tg4	1	8	Uversky	Uversky	NNP
cord-310847-63gh2tg4	1	9	,	,	,
cord-310847-63gh2tg4	1	10	Vladimir	Vladimir	NNP
cord-310847-63gh2tg4	1	11	N	n	CD
cord-310847-63gh2tg4	1	12	title	title	NN
cord-310847-63gh2tg4	1	13	:	:	:
cord-310847-63gh2tg4	1	14	The	the	DT
cord-310847-63gh2tg4	1	15	alphabet	alphabet	NN
cord-310847-63gh2tg4	1	16	of	of	IN
cord-310847-63gh2tg4	1	17	intrinsic	intrinsic	JJ
cord-310847-63gh2tg4	1	18	disorder	disorder	NN
cord-310847-63gh2tg4	1	19	:	:	:
cord-310847-63gh2tg4	1	20	II	II	NNP
cord-310847-63gh2tg4	1	21	.	.	.
cord-310847-63gh2tg4	2	1	Various	various	JJ
cord-310847-63gh2tg4	2	2	roles	role	NNS
cord-310847-63gh2tg4	2	3	of	of	IN
cord-310847-63gh2tg4	2	4	glutamic	glutamic	NN
cord-310847-63gh2tg4	2	5	acid	acid	NN
cord-310847-63gh2tg4	2	6	in	in	IN
cord-310847-63gh2tg4	2	7	ordered	order	VBN
cord-310847-63gh2tg4	2	8	and	and	CC
cord-310847-63gh2tg4	2	9	intrinsically	intrinsically	RB
cord-310847-63gh2tg4	2	10	disordered	disordered	JJ
cord-310847-63gh2tg4	2	11	proteins	protein	NNS
cord-310847-63gh2tg4	2	12	date	date	NN
cord-310847-63gh2tg4	2	13	:	:	:
cord-310847-63gh2tg4	2	14	2013	2013	CD
cord-310847-63gh2tg4	2	15	-	-	HYPH
cord-310847-63gh2tg4	2	16	04	04	CD
cord-310847-63gh2tg4	2	17	-	-	HYPH
cord-310847-63gh2tg4	2	18	01	01	CD
cord-310847-63gh2tg4	2	19	journal	journal	NN
cord-310847-63gh2tg4	2	20	:	:	:
cord-310847-63gh2tg4	3	1	Intrinsically	intrinsically	RB
cord-310847-63gh2tg4	4	1	Disord	Disord	NNP
cord-310847-63gh2tg4	4	2	Proteins	protein	NNS
cord-310847-63gh2tg4	4	3	DOI	DOI	NNP
cord-310847-63gh2tg4	4	4	:	:	:
cord-310847-63gh2tg4	5	1	10.4161	10.4161	CD
cord-310847-63gh2tg4	5	2	/	/	SYM
cord-310847-63gh2tg4	5	3	idp.24684	idp.24684	NN
cord-310847-63gh2tg4	5	4	sha	sha	NNP
cord-310847-63gh2tg4	5	5	:	:	:
cord-310847-63gh2tg4	6	1	5b0eeabeded14c9e02fc7bcfacb52a8fa0b3ae3c	5b0eeabeded14c9e02fc7bcfacb52a8fa0b3ae3c	CD
cord-310847-63gh2tg4	6	2	doc_id	doc_id	CD
cord-310847-63gh2tg4	6	3	:	:	:
cord-310847-63gh2tg4	6	4	310847	310847	CD
cord-310847-63gh2tg4	6	5	cord_uid	cord_uid	NNS
cord-310847-63gh2tg4	6	6	:	:	:
cord-310847-63gh2tg4	7	1	63gh2tg4	63gh2tg4	CD
cord-310847-63gh2tg4	8	1	The	the	DT
cord-310847-63gh2tg4	8	2	ability	ability	NN
cord-310847-63gh2tg4	8	3	of	of	IN
cord-310847-63gh2tg4	8	4	a	a	DT
cord-310847-63gh2tg4	8	5	protein	protein	NN
cord-310847-63gh2tg4	8	6	to	to	TO
cord-310847-63gh2tg4	8	7	fold	fold	VB
cord-310847-63gh2tg4	8	8	into	into	IN
cord-310847-63gh2tg4	8	9	unique	unique	JJ
cord-310847-63gh2tg4	8	10	functional	functional	JJ
cord-310847-63gh2tg4	8	11	state	state	NN
cord-310847-63gh2tg4	8	12	or	or	CC
cord-310847-63gh2tg4	8	13	to	to	TO
cord-310847-63gh2tg4	8	14	stay	stay	VB
cord-310847-63gh2tg4	8	15	intrinsically	intrinsically	RB
cord-310847-63gh2tg4	8	16	disordered	disordered	JJ
cord-310847-63gh2tg4	8	17	is	be	VBZ
cord-310847-63gh2tg4	8	18	encoded	encode	VBN
cord-310847-63gh2tg4	8	19	in	in	IN
cord-310847-63gh2tg4	8	20	its	-PRON-	PRP$
cord-310847-63gh2tg4	8	21	amino	amino	NN
cord-310847-63gh2tg4	8	22	acid	acid	NN
cord-310847-63gh2tg4	8	23	sequence	sequence	NN
cord-310847-63gh2tg4	8	24	.	.	.
cord-310847-63gh2tg4	9	1	Both	both	DT
cord-310847-63gh2tg4	9	2	ordered	order	VBD
cord-310847-63gh2tg4	9	3	and	and	CC
cord-310847-63gh2tg4	9	4	intrinsically	intrinsically	RB
cord-310847-63gh2tg4	9	5	disordered	disordered	JJ
cord-310847-63gh2tg4	9	6	proteins	protein	NNS
cord-310847-63gh2tg4	9	7	(	(	-LRB-
cord-310847-63gh2tg4	9	8	IDPs	IDPs	NNP
cord-310847-63gh2tg4	9	9	)	)	-RRB-
cord-310847-63gh2tg4	9	10	are	be	VBP
cord-310847-63gh2tg4	9	11	natural	natural	JJ
cord-310847-63gh2tg4	9	12	polypeptides	polypeptide	NNS
cord-310847-63gh2tg4	9	13	that	that	WDT
cord-310847-63gh2tg4	9	14	use	use	VBP
cord-310847-63gh2tg4	9	15	the	the	DT
cord-310847-63gh2tg4	9	16	same	same	JJ
cord-310847-63gh2tg4	9	17	arsenal	arsenal	NN
cord-310847-63gh2tg4	9	18	of	of	IN
cord-310847-63gh2tg4	9	19	20	20	CD
cord-310847-63gh2tg4	9	20	proteinogenic	proteinogenic	JJ
cord-310847-63gh2tg4	9	21	amino	amino	NN
cord-310847-63gh2tg4	9	22	acid	acid	NN
cord-310847-63gh2tg4	9	23	residues	residue	NNS
cord-310847-63gh2tg4	9	24	as	as	IN
cord-310847-63gh2tg4	9	25	their	-PRON-	PRP$
cord-310847-63gh2tg4	9	26	major	major	JJ
cord-310847-63gh2tg4	9	27	building	building	NN
cord-310847-63gh2tg4	9	28	blocks	block	NNS
cord-310847-63gh2tg4	9	29	.	.	.
cord-310847-63gh2tg4	10	1	The	the	DT
cord-310847-63gh2tg4	10	2	exceptional	exceptional	JJ
cord-310847-63gh2tg4	10	3	structural	structural	JJ
cord-310847-63gh2tg4	10	4	plasticity	plasticity	NN
cord-310847-63gh2tg4	10	5	of	of	IN
cord-310847-63gh2tg4	10	6	IDPs	IDPs	NNP
cord-310847-63gh2tg4	10	7	,	,	,
cord-310847-63gh2tg4	10	8	their	-PRON-	PRP$
cord-310847-63gh2tg4	10	9	capability	capability	NN
cord-310847-63gh2tg4	10	10	to	to	TO
cord-310847-63gh2tg4	10	11	exist	exist	VB
cord-310847-63gh2tg4	10	12	as	as	IN
cord-310847-63gh2tg4	10	13	heterogeneous	heterogeneous	JJ
cord-310847-63gh2tg4	10	14	structural	structural	JJ
cord-310847-63gh2tg4	10	15	ensembles	ensemble	NNS
cord-310847-63gh2tg4	10	16	and	and	CC
cord-310847-63gh2tg4	10	17	their	-PRON-	PRP$
cord-310847-63gh2tg4	10	18	wide	wide	JJ
cord-310847-63gh2tg4	10	19	array	array	NN
cord-310847-63gh2tg4	10	20	of	of	IN
cord-310847-63gh2tg4	10	21	important	important	JJ
cord-310847-63gh2tg4	10	22	disorder	disorder	NN
cord-310847-63gh2tg4	10	23	-	-	HYPH
cord-310847-63gh2tg4	10	24	based	base	VBN
cord-310847-63gh2tg4	10	25	biological	biological	JJ
cord-310847-63gh2tg4	10	26	functions	function	NNS
cord-310847-63gh2tg4	10	27	that	that	WDT
cord-310847-63gh2tg4	10	28	complements	complement	VBZ
cord-310847-63gh2tg4	10	29	functional	functional	JJ
cord-310847-63gh2tg4	10	30	repertoire	repertoire	NN
cord-310847-63gh2tg4	10	31	of	of	IN
cord-310847-63gh2tg4	10	32	ordered	order	VBN
cord-310847-63gh2tg4	10	33	proteins	protein	NNS
cord-310847-63gh2tg4	10	34	are	be	VBP
cord-310847-63gh2tg4	10	35	all	all	DT
cord-310847-63gh2tg4	10	36	rooted	root	VBN
cord-310847-63gh2tg4	10	37	within	within	IN
cord-310847-63gh2tg4	10	38	the	the	DT
cord-310847-63gh2tg4	10	39	peculiar	peculiar	JJ
cord-310847-63gh2tg4	10	40	differential	differential	JJ
cord-310847-63gh2tg4	10	41	usage	usage	NN
cord-310847-63gh2tg4	10	42	of	of	IN
cord-310847-63gh2tg4	10	43	these	these	DT
cord-310847-63gh2tg4	10	44	building	building	NN
cord-310847-63gh2tg4	10	45	blocks	block	NNS
cord-310847-63gh2tg4	10	46	by	by	IN
cord-310847-63gh2tg4	10	47	ordered	order	VBN
cord-310847-63gh2tg4	10	48	proteins	protein	NNS
cord-310847-63gh2tg4	10	49	and	and	CC
cord-310847-63gh2tg4	10	50	IDPs	idp	NNS
cord-310847-63gh2tg4	10	51	.	.	.
cord-310847-63gh2tg4	11	1	In	in	IN
cord-310847-63gh2tg4	11	2	fact	fact	NN
cord-310847-63gh2tg4	11	3	,	,	,
cord-310847-63gh2tg4	11	4	some	some	DT
cord-310847-63gh2tg4	11	5	residues	residue	NNS
cord-310847-63gh2tg4	11	6	(	(	-LRB-
cord-310847-63gh2tg4	11	7	so	so	RB
cord-310847-63gh2tg4	11	8	-	-	HYPH
cord-310847-63gh2tg4	11	9	called	call	VBN
cord-310847-63gh2tg4	11	10	disorder	disorder	NN
cord-310847-63gh2tg4	11	11	-	-	HYPH
cord-310847-63gh2tg4	11	12	promoting	promote	VBG
cord-310847-63gh2tg4	11	13	residues	residue	NNS
cord-310847-63gh2tg4	11	14	)	)	-RRB-
cord-310847-63gh2tg4	11	15	are	be	VBP
cord-310847-63gh2tg4	11	16	noticeably	noticeably	RB
cord-310847-63gh2tg4	11	17	more	more	RBR
cord-310847-63gh2tg4	11	18	common	common	JJ
cord-310847-63gh2tg4	11	19	in	in	IN
cord-310847-63gh2tg4	11	20	IDPs	idp	NNS
cord-310847-63gh2tg4	11	21	than	than	IN
cord-310847-63gh2tg4	11	22	in	in	IN
cord-310847-63gh2tg4	11	23	sequences	sequence	NNS
cord-310847-63gh2tg4	11	24	of	of	IN
cord-310847-63gh2tg4	11	25	ordered	order	VBN
cord-310847-63gh2tg4	11	26	proteins	protein	NNS
cord-310847-63gh2tg4	11	27	,	,	,
cord-310847-63gh2tg4	11	28	which	which	WDT
cord-310847-63gh2tg4	11	29	,	,	,
cord-310847-63gh2tg4	11	30	in	in	IN
cord-310847-63gh2tg4	11	31	their	-PRON-	PRP$
cord-310847-63gh2tg4	11	32	turn	turn	NN
cord-310847-63gh2tg4	11	33	,	,	,
cord-310847-63gh2tg4	11	34	are	be	VBP
cord-310847-63gh2tg4	11	35	enriched	enrich	VBN
cord-310847-63gh2tg4	11	36	in	in	IN
cord-310847-63gh2tg4	11	37	several	several	JJ
cord-310847-63gh2tg4	11	38	order	order	NN
cord-310847-63gh2tg4	11	39	-	-	HYPH
cord-310847-63gh2tg4	11	40	promoting	promote	VBG
cord-310847-63gh2tg4	11	41	residues	residue	NNS
cord-310847-63gh2tg4	11	42	.	.	.
cord-310847-63gh2tg4	12	1	Furthermore	furthermore	RB
cord-310847-63gh2tg4	12	2	,	,	,
cord-310847-63gh2tg4	12	3	residues	residue	NNS
cord-310847-63gh2tg4	12	4	can	can	MD
cord-310847-63gh2tg4	12	5	be	be	VB
cord-310847-63gh2tg4	12	6	arranged	arrange	VBN
cord-310847-63gh2tg4	12	7	according	accord	VBG
cord-310847-63gh2tg4	12	8	to	to	IN
cord-310847-63gh2tg4	12	9	their	-PRON-	PRP$
cord-310847-63gh2tg4	12	10	“	"	``
cord-310847-63gh2tg4	12	11	disorder	disorder	NN
cord-310847-63gh2tg4	12	12	promoting	promote	VBG
cord-310847-63gh2tg4	12	13	potencies	potency	NNS
cord-310847-63gh2tg4	12	14	,	,	,
cord-310847-63gh2tg4	12	15	”	"	''
cord-310847-63gh2tg4	12	16	which	which	WDT
cord-310847-63gh2tg4	12	17	are	be	VBP
cord-310847-63gh2tg4	12	18	evaluated	evaluate	VBN
cord-310847-63gh2tg4	12	19	based	base	VBN
cord-310847-63gh2tg4	12	20	on	on	IN
cord-310847-63gh2tg4	12	21	the	the	DT
cord-310847-63gh2tg4	12	22	relative	relative	JJ
cord-310847-63gh2tg4	12	23	abundances	abundance	NNS
cord-310847-63gh2tg4	12	24	of	of	IN
cord-310847-63gh2tg4	12	25	various	various	JJ
cord-310847-63gh2tg4	12	26	amino	amino	NN
cord-310847-63gh2tg4	12	27	acids	acid	NNS
cord-310847-63gh2tg4	12	28	in	in	IN
cord-310847-63gh2tg4	12	29	ordered	order	VBN
cord-310847-63gh2tg4	12	30	and	and	CC
cord-310847-63gh2tg4	12	31	disordered	disordered	JJ
cord-310847-63gh2tg4	12	32	proteins	protein	NNS
cord-310847-63gh2tg4	12	33	.	.	.
cord-310847-63gh2tg4	13	1	This	this	DT
cord-310847-63gh2tg4	13	2	review	review	NN
cord-310847-63gh2tg4	13	3	continues	continue	VBZ
cord-310847-63gh2tg4	13	4	a	a	DT
cord-310847-63gh2tg4	13	5	series	series	NN
cord-310847-63gh2tg4	13	6	of	of	IN
cord-310847-63gh2tg4	13	7	publications	publication	NNS
cord-310847-63gh2tg4	13	8	on	on	IN
cord-310847-63gh2tg4	13	9	the	the	DT
cord-310847-63gh2tg4	13	10	roles	role	NNS
cord-310847-63gh2tg4	13	11	of	of	IN
cord-310847-63gh2tg4	13	12	different	different	JJ
cord-310847-63gh2tg4	13	13	amino	amino	NN
cord-310847-63gh2tg4	13	14	acids	acid	NNS
cord-310847-63gh2tg4	13	15	in	in	IN
cord-310847-63gh2tg4	13	16	defining	define	VBG
cord-310847-63gh2tg4	13	17	the	the	DT
cord-310847-63gh2tg4	13	18	phenomenon	phenomenon	NN
cord-310847-63gh2tg4	13	19	of	of	IN
cord-310847-63gh2tg4	13	20	protein	protein	NN
cord-310847-63gh2tg4	13	21	intrinsic	intrinsic	JJ
cord-310847-63gh2tg4	13	22	disorder	disorder	NN
cord-310847-63gh2tg4	13	23	and	and	CC
cord-310847-63gh2tg4	13	24	concerns	concern	NNS
cord-310847-63gh2tg4	13	25	glutamic	glutamic	NN
cord-310847-63gh2tg4	13	26	acid	acid	NN
cord-310847-63gh2tg4	13	27	,	,	,
cord-310847-63gh2tg4	13	28	which	which	WDT
cord-310847-63gh2tg4	13	29	is	be	VBZ
cord-310847-63gh2tg4	13	30	the	the	DT
cord-310847-63gh2tg4	13	31	second	second	JJ
cord-310847-63gh2tg4	13	32	most	most	JJS
cord-310847-63gh2tg4	13	33	disorder	disorder	NN
cord-310847-63gh2tg4	13	34	-	-	HYPH
cord-310847-63gh2tg4	13	35	promoting	promote	VBG
cord-310847-63gh2tg4	13	36	residue	residue	NN
cord-310847-63gh2tg4	13	37	.	.	.
cord-310847-63gh2tg4	14	1	Intrinsically	intrinsically	RB
cord-310847-63gh2tg4	14	2	disordered	disordered	JJ
cord-310847-63gh2tg4	14	3	proteins	protein	NNS
cord-310847-63gh2tg4	14	4	(	(	-LRB-
cord-310847-63gh2tg4	14	5	IDPs	IDPs	NNP
cord-310847-63gh2tg4	14	6	)	)	-RRB-
cord-310847-63gh2tg4	14	7	and	and	CC
cord-310847-63gh2tg4	14	8	intrinsically	intrinsically	RB
cord-310847-63gh2tg4	14	9	disordered	disordered	JJ
cord-310847-63gh2tg4	14	10	protein	protein	NN
cord-310847-63gh2tg4	14	11	regions	region	NNS
cord-310847-63gh2tg4	14	12	(	(	-LRB-
cord-310847-63gh2tg4	14	13	IDPRs	IDPRs	NNP
cord-310847-63gh2tg4	14	14	)	)	-RRB-
cord-310847-63gh2tg4	14	15	are	be	VBP
cord-310847-63gh2tg4	14	16	new	new	JJ
cord-310847-63gh2tg4	14	17	exciting	exciting	JJ
cord-310847-63gh2tg4	14	18	members	member	NNS
cord-310847-63gh2tg4	14	19	of	of	IN
cord-310847-63gh2tg4	14	20	the	the	DT
cord-310847-63gh2tg4	14	21	protein	protein	NN
cord-310847-63gh2tg4	14	22	kingdom	kingdom	NN
cord-310847-63gh2tg4	14	23	.	.	.
cord-310847-63gh2tg4	15	1	1	1	CD
cord-310847-63gh2tg4	15	2	,	,	,
cord-310847-63gh2tg4	15	3	2	2	CD
cord-310847-63gh2tg4	15	4	They	-PRON-	PRP
cord-310847-63gh2tg4	15	5	are	be	VBP
cord-310847-63gh2tg4	15	6	highly	highly	RB
cord-310847-63gh2tg4	15	7	abundant	abundant	JJ
cord-310847-63gh2tg4	15	8	in	in	IN
cord-310847-63gh2tg4	15	9	nature	nature	NN
cord-310847-63gh2tg4	15	10	,	,	.
cord-310847-63gh2tg4	16	1	[	[	-LRB-
cord-310847-63gh2tg4	16	2	3	3	CD
cord-310847-63gh2tg4	16	3	]	]	-RRB-
cord-310847-63gh2tg4	16	4	[	[	-LRB-
cord-310847-63gh2tg4	16	5	4	4	CD
cord-310847-63gh2tg4	16	6	]	]	-RRB-
cord-310847-63gh2tg4	16	7	[	[	-LRB-
cord-310847-63gh2tg4	16	8	5	5	CD
cord-310847-63gh2tg4	16	9	]	]	-RRB-
cord-310847-63gh2tg4	16	10	[	[	-LRB-
cord-310847-63gh2tg4	16	11	6	6	CD
cord-310847-63gh2tg4	16	12	]	]	-RRB-
cord-310847-63gh2tg4	16	13	[	[	-LRB-
cord-310847-63gh2tg4	16	14	7	7	CD
cord-310847-63gh2tg4	16	15	]	]	-RRB-
cord-310847-63gh2tg4	16	16	possess	possess	VBP
cord-310847-63gh2tg4	16	17	numerous	numerous	JJ
cord-310847-63gh2tg4	16	18	intriguing	intriguing	JJ
cord-310847-63gh2tg4	16	19	properties	property	NNS
cord-310847-63gh2tg4	16	20	,	,	,
cord-310847-63gh2tg4	16	21	8	8	CD
cord-310847-63gh2tg4	16	22	are	be	VBP
cord-310847-63gh2tg4	16	23	intimately	intimately	RB
cord-310847-63gh2tg4	16	24	involved	involved	JJ
cord-310847-63gh2tg4	16	25	in	in	IN
cord-310847-63gh2tg4	16	26	various	various	JJ
cord-310847-63gh2tg4	16	27	cellular	cellular	JJ
cord-310847-63gh2tg4	16	28	processes	process	NNS
cord-310847-63gh2tg4	16	29	[	[	-LRB-
cord-310847-63gh2tg4	16	30	9	9	CD
cord-310847-63gh2tg4	16	31	]	]	-RRB-
cord-310847-63gh2tg4	16	32	[	[	-LRB-
cord-310847-63gh2tg4	16	33	10	10	CD
cord-310847-63gh2tg4	16	34	]	]	-RRB-
cord-310847-63gh2tg4	16	35	[	[	-LRB-
cord-310847-63gh2tg4	16	36	11	11	CD
cord-310847-63gh2tg4	16	37	]	]	-RRB-
cord-310847-63gh2tg4	16	38	[	[	-LRB-
cord-310847-63gh2tg4	16	39	12	12	CD
cord-310847-63gh2tg4	16	40	]	]	-RRB-
cord-310847-63gh2tg4	16	41	[	[	-LRB-
cord-310847-63gh2tg4	16	42	13	13	CD
cord-310847-63gh2tg4	16	43	]	]	-RRB-
cord-310847-63gh2tg4	16	44	[	[	-LRB-
cord-310847-63gh2tg4	16	45	14	14	CD
cord-310847-63gh2tg4	16	46	]	]	-RRB-
cord-310847-63gh2tg4	16	47	[	[	-LRB-
cord-310847-63gh2tg4	16	48	15	15	CD
cord-310847-63gh2tg4	16	49	]	]	-RRB-
cord-310847-63gh2tg4	16	50	[	[	-LRB-
cord-310847-63gh2tg4	16	51	16	16	CD
cord-310847-63gh2tg4	16	52	]	]	-RRB-
cord-310847-63gh2tg4	16	53	[	[	-LRB-
cord-310847-63gh2tg4	16	54	17	17	CD
cord-310847-63gh2tg4	16	55	]	]	-RRB-
cord-310847-63gh2tg4	16	56	[	[	-LRB-
cord-310847-63gh2tg4	16	57	18	18	CD
cord-310847-63gh2tg4	16	58	]	]	-RRB-
cord-310847-63gh2tg4	16	59	[	[	-LRB-
cord-310847-63gh2tg4	16	60	19	19	CD
cord-310847-63gh2tg4	16	61	]	]	-RRB-
cord-310847-63gh2tg4	16	62	[	[	-LRB-
cord-310847-63gh2tg4	16	63	20	20	CD
cord-310847-63gh2tg4	16	64	]	]	-RRB-
cord-310847-63gh2tg4	16	65	[	[	-LRB-
cord-310847-63gh2tg4	16	66	21	21	CD
cord-310847-63gh2tg4	16	67	]	]	-RRB-
cord-310847-63gh2tg4	16	68	[	[	-LRB-
cord-310847-63gh2tg4	16	69	22	22	CD
cord-310847-63gh2tg4	16	70	]	]	-RRB-
cord-310847-63gh2tg4	16	71	[	[	-LRB-
cord-310847-63gh2tg4	16	72	23	23	CD
cord-310847-63gh2tg4	16	73	]	]	-RRB-
cord-310847-63gh2tg4	16	74	and	and	CC
cord-310847-63gh2tg4	16	75	are	be	VBP
cord-310847-63gh2tg4	16	76	commonly	commonly	RB
cord-310847-63gh2tg4	16	77	found	find	VBN
cord-310847-63gh2tg4	16	78	to	to	TO
cord-310847-63gh2tg4	16	79	be	be	VB
cord-310847-63gh2tg4	16	80	related	relate	VBN
cord-310847-63gh2tg4	16	81	to	to	IN
cord-310847-63gh2tg4	16	82	the	the	DT
cord-310847-63gh2tg4	16	83	pathogenesis	pathogenesis	NN
cord-310847-63gh2tg4	16	84	of	of	IN
cord-310847-63gh2tg4	16	85	various	various	JJ
cord-310847-63gh2tg4	16	86	diseases	disease	NNS
cord-310847-63gh2tg4	16	87	.	.	.
cord-310847-63gh2tg4	17	1	13	13	CD
cord-310847-63gh2tg4	17	2	,	,	,
cord-310847-63gh2tg4	17	3	[	[	-LRB-
cord-310847-63gh2tg4	17	4	24	24	CD
cord-310847-63gh2tg4	17	5	]	]	-RRB-
cord-310847-63gh2tg4	17	6	[	[	-LRB-
cord-310847-63gh2tg4	17	7	25	25	CD
cord-310847-63gh2tg4	17	8	]	]	-RRB-
cord-310847-63gh2tg4	17	9	[	[	-LRB-
cord-310847-63gh2tg4	17	10	26	26	CD
cord-310847-63gh2tg4	17	11	]	]	-RRB-
cord-310847-63gh2tg4	17	12	[	[	-LRB-
cord-310847-63gh2tg4	17	13	27	27	CD
cord-310847-63gh2tg4	17	14	]	]	-RRB-
cord-310847-63gh2tg4	17	15	[	[	-LRB-
cord-310847-63gh2tg4	17	16	28	28	CD
cord-310847-63gh2tg4	17	17	]	]	-RRB-
cord-310847-63gh2tg4	17	18	[	[	-LRB-
cord-310847-63gh2tg4	17	19	29	29	CD
cord-310847-63gh2tg4	17	20	]	]	-RRB-
cord-310847-63gh2tg4	18	1	The	the	DT
cord-310847-63gh2tg4	18	2	common	common	JJ
cord-310847-63gh2tg4	18	3	theme	theme	NN
cord-310847-63gh2tg4	18	4	of	of	IN
cord-310847-63gh2tg4	18	5	protein	protein	NN
cord-310847-63gh2tg4	18	6	disorder	disorder	NN
cord-310847-63gh2tg4	18	7	-	-	HYPH
cord-310847-63gh2tg4	18	8	based	base	VBN
cord-310847-63gh2tg4	18	9	functionality	functionality	NN
cord-310847-63gh2tg4	18	10	is	be	VBZ
cord-310847-63gh2tg4	18	11	recognition	recognition	NN
cord-310847-63gh2tg4	18	12	,	,	,
cord-310847-63gh2tg4	18	13	and	and	CC
cord-310847-63gh2tg4	18	14	IDPs	IDPs	NNP
cord-310847-63gh2tg4	18	15	/	/	SYM
cord-310847-63gh2tg4	18	16	IDPRs	IDPRs	NNPS
cord-310847-63gh2tg4	18	17	are	be	VBP
cord-310847-63gh2tg4	18	18	frequently	frequently	RB
cord-310847-63gh2tg4	18	19	involved	involve	VBN
cord-310847-63gh2tg4	18	20	in	in	IN
cord-310847-63gh2tg4	18	21	complex	complex	JJ
cord-310847-63gh2tg4	18	22	protein	protein	NN
cord-310847-63gh2tg4	18	23	-	-	HYPH
cord-310847-63gh2tg4	18	24	protein	protein	NN
cord-310847-63gh2tg4	18	25	,	,	,
cord-310847-63gh2tg4	18	26	protein	protein	NN
cord-310847-63gh2tg4	18	27	-	-	HYPH
cord-310847-63gh2tg4	18	28	nucleic	nucleic	JJ
cord-310847-63gh2tg4	18	29	acid	acid	NN
cord-310847-63gh2tg4	18	30	and	and	CC
cord-310847-63gh2tg4	18	31	protein	protein	NN
cord-310847-63gh2tg4	18	32	-	-	HYPH
cord-310847-63gh2tg4	18	33	small	small	JJ
cord-310847-63gh2tg4	18	34	molecule	molecule	NN
cord-310847-63gh2tg4	18	35	interactions	interaction	NNS
cord-310847-63gh2tg4	18	36	.	.	.
cord-310847-63gh2tg4	19	1	Some	some	DT
cord-310847-63gh2tg4	19	2	of	of	IN
cord-310847-63gh2tg4	19	3	these	these	DT
cord-310847-63gh2tg4	19	4	interactions	interaction	NNS
cord-310847-63gh2tg4	19	5	can	can	MD
cord-310847-63gh2tg4	19	6	induce	induce	VB
cord-310847-63gh2tg4	19	7	a	a	DT
cord-310847-63gh2tg4	19	8	disorder	disorder	NN
cord-310847-63gh2tg4	19	9	-	-	HYPH
cord-310847-63gh2tg4	19	10	order	order	NN
cord-310847-63gh2tg4	19	11	transition	transition	NN
cord-310847-63gh2tg4	19	12	in	in	IN
cord-310847-63gh2tg4	19	13	the	the	DT
cord-310847-63gh2tg4	19	14	entire	entire	JJ
cord-310847-63gh2tg4	19	15	IDP	IDP	NNP
cord-310847-63gh2tg4	19	16	or	or	CC
cord-310847-63gh2tg4	19	17	in	in	IN
cord-310847-63gh2tg4	19	18	its	-PRON-	PRP$
cord-310847-63gh2tg4	19	19	part	part	NN
cord-310847-63gh2tg4	19	20	.	.	.
cord-310847-63gh2tg4	20	1	5	5	LS
cord-310847-63gh2tg4	20	2	,	,	,
cord-310847-63gh2tg4	20	3	[	[	-LRB-
cord-310847-63gh2tg4	20	4	9	9	CD
cord-310847-63gh2tg4	20	5	]	]	-RRB-
cord-310847-63gh2tg4	20	6	[	[	-LRB-
cord-310847-63gh2tg4	20	7	10	10	CD
cord-310847-63gh2tg4	20	8	]	]	-RRB-
cord-310847-63gh2tg4	20	9	[	[	-LRB-
cord-310847-63gh2tg4	20	10	11	11	CD
cord-310847-63gh2tg4	20	11	]	]	-RRB-
cord-310847-63gh2tg4	20	12	[	[	-LRB-
cord-310847-63gh2tg4	20	13	12	12	CD
cord-310847-63gh2tg4	20	14	]	]	-RRB-
cord-310847-63gh2tg4	20	15	15	15	CD
cord-310847-63gh2tg4	20	16	,	,	,
cord-310847-63gh2tg4	20	17	23	23	CD
cord-310847-63gh2tg4	20	18	,	,	,
cord-310847-63gh2tg4	20	19	[	[	-LRB-
cord-310847-63gh2tg4	20	20	30	30	CD
cord-310847-63gh2tg4	20	21	]	]	-RRB-
cord-310847-63gh2tg4	20	22	[	[	-LRB-
cord-310847-63gh2tg4	20	23	31	31	CD
cord-310847-63gh2tg4	20	24	]	]	-RRB-
cord-310847-63gh2tg4	21	1	[	[	-LRB-
cord-310847-63gh2tg4	21	2	32	32	CD
cord-310847-63gh2tg4	21	3	]	]	-RRB-
cord-310847-63gh2tg4	21	4	[	[	-LRB-
cord-310847-63gh2tg4	21	5	33	33	CD
cord-310847-63gh2tg4	21	6	]	]	-RRB-
cord-310847-63gh2tg4	21	7	[	[	-LRB-
cord-310847-63gh2tg4	21	8	34	34	CD
cord-310847-63gh2tg4	21	9	]	]	-RRB-
cord-310847-63gh2tg4	22	1	[	[	-LRB-
cord-310847-63gh2tg4	22	2	35	35	CD
cord-310847-63gh2tg4	22	3	]	]	-RRB-
cord-310847-63gh2tg4	22	4	[	[	-LRB-
cord-310847-63gh2tg4	22	5	36	36	CD
cord-310847-63gh2tg4	22	6	]	]	-RRB-
cord-310847-63gh2tg4	23	1	Furthermore	furthermore	RB
cord-310847-63gh2tg4	23	2	,	,	,
cord-310847-63gh2tg4	23	3	intrinsic	intrinsic	JJ
cord-310847-63gh2tg4	23	4	disorder	disorder	NN
cord-310847-63gh2tg4	23	5	opens	open	VBZ
cord-310847-63gh2tg4	23	6	a	a	DT
cord-310847-63gh2tg4	23	7	unique	unique	JJ
cord-310847-63gh2tg4	23	8	capability	capability	NN
cord-310847-63gh2tg4	23	9	for	for	IN
cord-310847-63gh2tg4	23	10	one	one	CD
cord-310847-63gh2tg4	23	11	protein	protein	NN
cord-310847-63gh2tg4	23	12	to	to	TO
cord-310847-63gh2tg4	23	13	be	be	VB
cord-310847-63gh2tg4	23	14	involved	involve	VBN
cord-310847-63gh2tg4	23	15	in	in	IN
cord-310847-63gh2tg4	23	16	interaction	interaction	NN
cord-310847-63gh2tg4	23	17	with	with	IN
cord-310847-63gh2tg4	23	18	several	several	JJ
cord-310847-63gh2tg4	23	19	unrelated	unrelated	JJ
cord-310847-63gh2tg4	23	20	binding	bind	VBG
cord-310847-63gh2tg4	23	21	partners	partner	NNS
cord-310847-63gh2tg4	23	22	and	and	CC
cord-310847-63gh2tg4	23	23	to	to	TO
cord-310847-63gh2tg4	23	24	gain	gain	VB
cord-310847-63gh2tg4	23	25	different	different	JJ
cord-310847-63gh2tg4	23	26	bound	bind	VBN
cord-310847-63gh2tg4	23	27	structures	structure	NNS
cord-310847-63gh2tg4	23	28	.	.	.
cord-310847-63gh2tg4	24	1	22	22	CD
cord-310847-63gh2tg4	24	2	,	,	,
cord-310847-63gh2tg4	24	3	37	37	CD
cord-310847-63gh2tg4	25	1	Some	some	DT
cord-310847-63gh2tg4	25	2	IDPs	idp	NNS
cord-310847-63gh2tg4	25	3	can	can	MD
cord-310847-63gh2tg4	25	4	form	form	VB
cord-310847-63gh2tg4	25	5	highly	highly	RB
cord-310847-63gh2tg4	25	6	stable	stable	JJ
cord-310847-63gh2tg4	25	7	complexes	complex	NNS
cord-310847-63gh2tg4	25	8	;	;	:
cord-310847-63gh2tg4	25	9	others	other	NNS
cord-310847-63gh2tg4	25	10	are	be	VBP
cord-310847-63gh2tg4	25	11	involved	involve	VBN
cord-310847-63gh2tg4	25	12	in	in	IN
cord-310847-63gh2tg4	25	13	signaling	signal	VBG
cord-310847-63gh2tg4	25	14	interactions	interaction	NNS
cord-310847-63gh2tg4	25	15	where	where	WRB
cord-310847-63gh2tg4	25	16	they	-PRON-	PRP
cord-310847-63gh2tg4	25	17	undergo	undergo	VBP
cord-310847-63gh2tg4	25	18	constant	constant	JJ
cord-310847-63gh2tg4	25	19	"	"	``
cord-310847-63gh2tg4	25	20	bound	bind	VBN
cord-310847-63gh2tg4	25	21	-	-	HYPH
cord-310847-63gh2tg4	25	22	unbound	unbound	JJ
cord-310847-63gh2tg4	25	23	"	"	''
cord-310847-63gh2tg4	25	24	transitions	transition	NNS
cord-310847-63gh2tg4	25	25	,	,	,
cord-310847-63gh2tg4	25	26	thus	thus	RB
cord-310847-63gh2tg4	25	27	acting	act	VBG
cord-310847-63gh2tg4	25	28	as	as	IN
cord-310847-63gh2tg4	25	29	dynamic	dynamic	JJ
cord-310847-63gh2tg4	25	30	and	and	CC
cord-310847-63gh2tg4	25	31	sensitive	sensitive	JJ
cord-310847-63gh2tg4	25	32	"	"	''
cord-310847-63gh2tg4	25	33	on	on	IN
cord-310847-63gh2tg4	25	34	-	-	HYPH
cord-310847-63gh2tg4	25	35	off	off	NN
cord-310847-63gh2tg4	25	36	"	"	''
cord-310847-63gh2tg4	25	37	switches	switch	NNS
cord-310847-63gh2tg4	25	38	.	.	.
cord-310847-63gh2tg4	26	1	These	these	DT
cord-310847-63gh2tg4	26	2	proteins	protein	NNS
cord-310847-63gh2tg4	26	3	typically	typically	RB
cord-310847-63gh2tg4	26	4	return	return	VBP
cord-310847-63gh2tg4	26	5	to	to	IN
cord-310847-63gh2tg4	26	6	their	-PRON-	PRP$
cord-310847-63gh2tg4	26	7	intrinsically	intrinsically	RB
cord-310847-63gh2tg4	26	8	disordered	disordered	JJ
cord-310847-63gh2tg4	26	9	state	state	NN
cord-310847-63gh2tg4	26	10	after	after	IN
cord-310847-63gh2tg4	26	11	the	the	DT
cord-310847-63gh2tg4	26	12	completion	completion	NN
cord-310847-63gh2tg4	26	13	of	of	IN
cord-310847-63gh2tg4	26	14	a	a	DT
cord-310847-63gh2tg4	26	15	particular	particular	JJ
cord-310847-63gh2tg4	26	16	function	function	NN
cord-310847-63gh2tg4	26	17	.	.	.
cord-310847-63gh2tg4	27	1	Many	many	JJ
cord-310847-63gh2tg4	27	2	of	of	IN
cord-310847-63gh2tg4	27	3	the	the	DT
cord-310847-63gh2tg4	27	4	IDPs	IDPs	NNP
cord-310847-63gh2tg4	27	5	/	/	SYM
cord-310847-63gh2tg4	27	6	IDPRs	IDPRs	NNPS
cord-310847-63gh2tg4	27	7	can	can	MD
cord-310847-63gh2tg4	27	8	gain	gain	VB
cord-310847-63gh2tg4	27	9	different	different	JJ
cord-310847-63gh2tg4	27	10	conformations	conformation	NNS
cord-310847-63gh2tg4	27	11	depending	depend	VBG
cord-310847-63gh2tg4	27	12	on	on	IN
cord-310847-63gh2tg4	27	13	the	the	DT
cord-310847-63gh2tg4	27	14	environmental	environmental	JJ
cord-310847-63gh2tg4	27	15	peculiarities	peculiarity	NNS
cord-310847-63gh2tg4	27	16	.	.	.
cord-310847-63gh2tg4	28	1	30	30	CD
cord-310847-63gh2tg4	28	2	,	,	,
cord-310847-63gh2tg4	28	3	37	37	CD
cord-310847-63gh2tg4	29	1	All	all	PDT
cord-310847-63gh2tg4	29	2	this	this	DT
cord-310847-63gh2tg4	29	3	constitutes	constitute	VBZ
cord-310847-63gh2tg4	29	4	an	an	DT
cord-310847-63gh2tg4	29	5	important	important	JJ
cord-310847-63gh2tg4	29	6	arsenal	arsenal	NN
cord-310847-63gh2tg4	29	7	of	of	IN
cord-310847-63gh2tg4	29	8	the	the	DT
cord-310847-63gh2tg4	29	9	unique	unique	JJ
cord-310847-63gh2tg4	29	10	physiological	physiological	JJ
cord-310847-63gh2tg4	29	11	properties	property	NNS
cord-310847-63gh2tg4	29	12	of	of	IN
cord-310847-63gh2tg4	29	13	IDPs	IDPs	NNP
cord-310847-63gh2tg4	29	14	/	/	SYM
cord-310847-63gh2tg4	29	15	IDPRs	IDPRs	NNP
cord-310847-63gh2tg4	29	16	that	that	WDT
cord-310847-63gh2tg4	29	17	determines	determine	VBZ
cord-310847-63gh2tg4	29	18	their	-PRON-	PRP$
cord-310847-63gh2tg4	29	19	ability	ability	NN
cord-310847-63gh2tg4	29	20	to	to	TO
cord-310847-63gh2tg4	29	21	exert	exert	VB
cord-310847-63gh2tg4	29	22	different	different	JJ
cord-310847-63gh2tg4	29	23	functions	function	NNS
cord-310847-63gh2tg4	29	24	in	in	IN
cord-310847-63gh2tg4	29	25	different	different	JJ
cord-310847-63gh2tg4	29	26	cellular	cellular	JJ
cord-310847-63gh2tg4	29	27	contests	contest	NNS
cord-310847-63gh2tg4	29	28	according	accord	VBG
cord-310847-63gh2tg4	29	29	to	to	IN
cord-310847-63gh2tg4	29	30	a	a	DT
cord-310847-63gh2tg4	29	31	specific	specific	JJ
cord-310847-63gh2tg4	29	32	conformational	conformational	JJ
cord-310847-63gh2tg4	29	33	state	state	NN
cord-310847-63gh2tg4	29	34	.	.	.
cord-310847-63gh2tg4	30	1	8	8	CD
cord-310847-63gh2tg4	31	1	The	the	DT
cord-310847-63gh2tg4	31	2	folding	folding	NN
cord-310847-63gh2tg4	31	3	-	-	HYPH
cord-310847-63gh2tg4	31	4	at	at	IN
cord-310847-63gh2tg4	31	5	-	-	HYPH
cord-310847-63gh2tg4	31	6	binding	bind	VBG
cord-310847-63gh2tg4	31	7	principle	principle	NN
cord-310847-63gh2tg4	31	8	is	be	VBZ
cord-310847-63gh2tg4	31	9	believed	believe	VBN
cord-310847-63gh2tg4	31	10	to	to	TO
cord-310847-63gh2tg4	31	11	help	help	VB
cord-310847-63gh2tg4	31	12	IDPs	IDPs	NNP
cord-310847-63gh2tg4	31	13	or	or	CC
cord-310847-63gh2tg4	31	14	IDPRs	IDPRs	NNPS
cord-310847-63gh2tg4	31	15	to	to	TO
cord-310847-63gh2tg4	31	16	obtain	obtain	VB
cord-310847-63gh2tg4	31	17	maximal	maximal	JJ
cord-310847-63gh2tg4	31	18	specificity	specificity	NN
cord-310847-63gh2tg4	31	19	in	in	IN
cord-310847-63gh2tg4	31	20	a	a	DT
cord-310847-63gh2tg4	31	21	protein	protein	NN
cord-310847-63gh2tg4	31	22	-	-	HYPH
cord-310847-63gh2tg4	31	23	protein	protein	NN
cord-310847-63gh2tg4	31	24	interaction	interaction	NN
cord-310847-63gh2tg4	31	25	without	without	IN
cord-310847-63gh2tg4	31	26	very	very	RB
cord-310847-63gh2tg4	31	27	high	high	JJ
cord-310847-63gh2tg4	31	28	affinity	affinity	NN
cord-310847-63gh2tg4	31	29	.	.	.
cord-310847-63gh2tg4	32	1	20	20	CD
cord-310847-63gh2tg4	33	1	This	this	DT
cord-310847-63gh2tg4	33	2	combination	combination	NN
cord-310847-63gh2tg4	33	3	of	of	IN
cord-310847-63gh2tg4	33	4	high	high	JJ
cord-310847-63gh2tg4	33	5	specificity	specificity	NN
cord-310847-63gh2tg4	33	6	with	with	IN
cord-310847-63gh2tg4	33	7	low	low	JJ
cord-310847-63gh2tg4	33	8	affinity	affinity	NN
cord-310847-63gh2tg4	33	9	defines	define	VBZ
cord-310847-63gh2tg4	33	10	the	the	DT
cord-310847-63gh2tg4	33	11	broad	broad	JJ
cord-310847-63gh2tg4	33	12	utilization	utilization	NN
cord-310847-63gh2tg4	33	13	of	of	IN
cord-310847-63gh2tg4	33	14	intrinsic	intrinsic	JJ
cord-310847-63gh2tg4	33	15	disorder	disorder	NN
cord-310847-63gh2tg4	33	16	in	in	IN
cord-310847-63gh2tg4	33	17	regulatory	regulatory	JJ
cord-310847-63gh2tg4	33	18	interactions	interaction	NNS
cord-310847-63gh2tg4	33	19	where	where	WRB
cord-310847-63gh2tg4	33	20	turning	turn	VBG
cord-310847-63gh2tg4	33	21	a	a	DT
cord-310847-63gh2tg4	33	22	signal	signal	NN
cord-310847-63gh2tg4	33	23	off	off	RP
cord-310847-63gh2tg4	33	24	is	be	VBZ
cord-310847-63gh2tg4	33	25	as	as	RB
cord-310847-63gh2tg4	33	26	important	important	JJ
cord-310847-63gh2tg4	33	27	as	as	IN
cord-310847-63gh2tg4	33	28	turning	turn	VBG
cord-310847-63gh2tg4	33	29	it	-PRON-	PRP
cord-310847-63gh2tg4	33	30	on	on	RP
cord-310847-63gh2tg4	33	31	.	.	.
cord-310847-63gh2tg4	34	1	10	10	CD
cord-310847-63gh2tg4	35	1	Although	although	IN
cord-310847-63gh2tg4	35	2	some	some	DT
cord-310847-63gh2tg4	35	3	partial	partial	JJ
cord-310847-63gh2tg4	35	4	folding	folding	NN
cord-310847-63gh2tg4	35	5	during	during	IN
cord-310847-63gh2tg4	35	6	the	the	DT
cord-310847-63gh2tg4	35	7	IDP/	IDP/	NNP
cord-310847-63gh2tg4	35	8	IDPR	IDPR	NNP
cord-310847-63gh2tg4	35	9	-	-	HYPH
cord-310847-63gh2tg4	35	10	based	base	VBN
cord-310847-63gh2tg4	35	11	interactions	interaction	NNS
cord-310847-63gh2tg4	35	12	is	be	VBZ
cord-310847-63gh2tg4	35	13	a	a	DT
cord-310847-63gh2tg4	35	14	widespread	widespread	JJ
cord-310847-63gh2tg4	35	15	phenomenon	phenomenon	NN
cord-310847-63gh2tg4	35	16	,	,	,
cord-310847-63gh2tg4	35	17	with	with	IN
cord-310847-63gh2tg4	35	18	significant	significant	JJ
cord-310847-63gh2tg4	35	19	fraction	fraction	NN
cord-310847-63gh2tg4	35	20	(	(	-LRB-
cord-310847-63gh2tg4	35	21	~1/3	~1/3	CD
cord-310847-63gh2tg4	35	22	)	)	-RRB-
cord-310847-63gh2tg4	35	23	of	of	IN
cord-310847-63gh2tg4	35	24	the	the	DT
cord-310847-63gh2tg4	35	25	interacting	interact	VBG
cord-310847-63gh2tg4	35	26	residues	residue	NNS
cord-310847-63gh2tg4	35	27	in	in	IN
cord-310847-63gh2tg4	35	28	IDPs	IDPs	NNP
cord-310847-63gh2tg4	35	29	/	/	SYM
cord-310847-63gh2tg4	35	30	IDPRs	IDPRs	NNP
cord-310847-63gh2tg4	35	31	adopting	adopt	VBG
cord-310847-63gh2tg4	35	32	α	α	NN
cord-310847-63gh2tg4	35	33	-	-	HYPH
cord-310847-63gh2tg4	35	34	helix	helix	NNP
cord-310847-63gh2tg4	35	35	,	,	,
cord-310847-63gh2tg4	35	36	β	β	NN
cord-310847-63gh2tg4	35	37	-	-	HYPH
cord-310847-63gh2tg4	35	38	strand	strand	NN
cord-310847-63gh2tg4	35	39	and	and	CC
cord-310847-63gh2tg4	35	40	irregular	irregular	JJ
cord-310847-63gh2tg4	35	41	structures	structure	NNS
cord-310847-63gh2tg4	35	42	,	,	,
cord-310847-63gh2tg4	35	43	31	31	CD
cord-310847-63gh2tg4	35	44	,	,	,
cord-310847-63gh2tg4	35	45	32	32	CD
cord-310847-63gh2tg4	35	46	there	there	EX
cord-310847-63gh2tg4	35	47	are	be	VBP
cord-310847-63gh2tg4	35	48	still	still	RB
cord-310847-63gh2tg4	35	49	many	many	JJ
cord-310847-63gh2tg4	35	50	other	other	JJ
cord-310847-63gh2tg4	35	51	IDPs	idp	NNS
cord-310847-63gh2tg4	35	52	/	/	SYM
cord-310847-63gh2tg4	35	53	IDPRs	IDPRs	NNP
cord-310847-63gh2tg4	35	54	that	that	WDT
cord-310847-63gh2tg4	35	55	are	be	VBP
cord-310847-63gh2tg4	35	56	involved	involve	VBN
cord-310847-63gh2tg4	35	57	in	in	IN
cord-310847-63gh2tg4	35	58	the	the	DT
cord-310847-63gh2tg4	35	59	formation	formation	NN
cord-310847-63gh2tg4	35	60	of	of	IN
cord-310847-63gh2tg4	35	61	"	"	``
cord-310847-63gh2tg4	35	62	fuzzy	fuzzy	JJ
cord-310847-63gh2tg4	35	63	complexes	complex	NNS
cord-310847-63gh2tg4	35	64	,	,	,
cord-310847-63gh2tg4	35	65	"	"	''
cord-310847-63gh2tg4	35	66	where	where	WRB
cord-310847-63gh2tg4	35	67	an	an	DT
cord-310847-63gh2tg4	35	68	IDP	IDP	NNP
cord-310847-63gh2tg4	35	69	/	/	SYM
cord-310847-63gh2tg4	35	70	IDPR	IDPR	NNP
cord-310847-63gh2tg4	35	71	keeps	keep	VBZ
cord-310847-63gh2tg4	35	72	a	a	DT
cord-310847-63gh2tg4	35	73	certain	certain	JJ
cord-310847-63gh2tg4	35	74	amount	amount	NN
cord-310847-63gh2tg4	35	75	of	of	IN
cord-310847-63gh2tg4	35	76	disorder	disorder	NN
cord-310847-63gh2tg4	35	77	in	in	IN
cord-310847-63gh2tg4	35	78	its	-PRON-	PRP$
cord-310847-63gh2tg4	35	79	bound	bind	VBN
cord-310847-63gh2tg4	35	80	conformation	conformation	NN
cord-310847-63gh2tg4	35	81	.	.	.
cord-310847-63gh2tg4	36	1	35	35	CD
cord-310847-63gh2tg4	36	2	,	,	,
cord-310847-63gh2tg4	36	3	[	[	-LRB-
cord-310847-63gh2tg4	36	4	38	38	CD
cord-310847-63gh2tg4	36	5	]	]	-RRB-
cord-310847-63gh2tg4	36	6	[	[	-LRB-
cord-310847-63gh2tg4	36	7	39	39	CD
cord-310847-63gh2tg4	36	8	]	]	-RRB-
cord-310847-63gh2tg4	37	1	[	[	-LRB-
cord-310847-63gh2tg4	37	2	40	40	CD
cord-310847-63gh2tg4	37	3	]	]	-RRB-
cord-310847-63gh2tg4	38	1	Often	often	RB
cord-310847-63gh2tg4	38	2	,	,	,
cord-310847-63gh2tg4	38	3	the	the	DT
cord-310847-63gh2tg4	38	4	interacting	interact	VBG
cord-310847-63gh2tg4	38	5	regions	region	NNS
cord-310847-63gh2tg4	38	6	in	in	IN
cord-310847-63gh2tg4	38	7	IDPs	idp	NNS
cord-310847-63gh2tg4	38	8	are	be	VBP
cord-310847-63gh2tg4	38	9	observed	observe	VBN
cord-310847-63gh2tg4	38	10	as	as	IN
cord-310847-63gh2tg4	38	11	loosely	loosely	RB
cord-310847-63gh2tg4	38	12	structured	structure	VBN
cord-310847-63gh2tg4	38	13	fragments	fragment	NNS
cord-310847-63gh2tg4	38	14	in	in	IN
cord-310847-63gh2tg4	38	15	their	-PRON-	PRP$
cord-310847-63gh2tg4	38	16	unbound	unbound	JJ
cord-310847-63gh2tg4	38	17	forms	form	NNS
cord-310847-63gh2tg4	38	18	.	.	.
cord-310847-63gh2tg4	39	1	These	these	DT
cord-310847-63gh2tg4	39	2	disorderbased	disorderbase	VBN
cord-310847-63gh2tg4	39	3	binding	binding	JJ
cord-310847-63gh2tg4	39	4	sites	site	NNS
cord-310847-63gh2tg4	39	5	are	be	VBP
cord-310847-63gh2tg4	39	6	known	know	VBN
cord-310847-63gh2tg4	39	7	as	as	IN
cord-310847-63gh2tg4	39	8	molecular	molecular	JJ
cord-310847-63gh2tg4	39	9	recognition	recognition	NN
cord-310847-63gh2tg4	39	10	elements	element	NNS
cord-310847-63gh2tg4	39	11	or	or	CC
cord-310847-63gh2tg4	39	12	features	feature	NNS
cord-310847-63gh2tg4	39	13	(	(	-LRB-
cord-310847-63gh2tg4	39	14	MoREs	MoREs	NNP
cord-310847-63gh2tg4	39	15	or	or	CC
cord-310847-63gh2tg4	39	16	MoRFs	MoRFs	NNP
cord-310847-63gh2tg4	39	17	)	)	-RRB-
cord-310847-63gh2tg4	39	18	,	,	,
cord-310847-63gh2tg4	39	19	30	30	CD
cord-310847-63gh2tg4	39	20	,	,	,
cord-310847-63gh2tg4	39	21	31	31	CD
cord-310847-63gh2tg4	39	22	preformed	preformed	JJ
cord-310847-63gh2tg4	39	23	structural	structural	JJ
cord-310847-63gh2tg4	39	24	elements	element	NNS
cord-310847-63gh2tg4	39	25	41	41	CD
cord-310847-63gh2tg4	39	26	or	or	CC
cord-310847-63gh2tg4	39	27	pre	pre	JJ
cord-310847-63gh2tg4	39	28	-	-	JJ
cord-310847-63gh2tg4	39	29	structured	structured	JJ
cord-310847-63gh2tg4	39	30	motifs	motif	NNS
cord-310847-63gh2tg4	39	31	(	(	-LRB-
cord-310847-63gh2tg4	39	32	PreSMos	presmos	NN
cord-310847-63gh2tg4	39	33	)	)	-RRB-
cord-310847-63gh2tg4	39	34	.	.	.
cord-310847-63gh2tg4	40	1	42	42	CD
cord-310847-63gh2tg4	41	1	Although	although	IN
cord-310847-63gh2tg4	41	2	the	the	DT
cord-310847-63gh2tg4	41	3	existence	existence	NN
cord-310847-63gh2tg4	41	4	of	of	IN
cord-310847-63gh2tg4	41	5	such	such	JJ
cord-310847-63gh2tg4	41	6	loosely	loosely	RB
cord-310847-63gh2tg4	41	7	structured	structure	VBN
cord-310847-63gh2tg4	41	8	regions	region	NNS
cord-310847-63gh2tg4	41	9	suggests	suggest	VBZ
cord-310847-63gh2tg4	41	10	that	that	IN
cord-310847-63gh2tg4	41	11	IDPs	IDPs	NNP
cord-310847-63gh2tg4	41	12	can	can	MD
cord-310847-63gh2tg4	41	13	adopt	adopt	VB
cord-310847-63gh2tg4	41	14	their	-PRON-	PRP$
cord-310847-63gh2tg4	41	15	bound	bind	VBN
cord-310847-63gh2tg4	41	16	structure(s	structure(s	NN
cord-310847-63gh2tg4	41	17	)	)	-RRB-
cord-310847-63gh2tg4	41	18	at	at	IN
cord-310847-63gh2tg4	41	19	a	a	DT
cord-310847-63gh2tg4	41	20	free	free	JJ
cord-310847-63gh2tg4	41	21	-	-	HYPH
cord-310847-63gh2tg4	41	22	energy	energy	NN
cord-310847-63gh2tg4	41	23	cost	cost	NN
cord-310847-63gh2tg4	41	24	that	that	WDT
cord-310847-63gh2tg4	41	25	is	be	VBZ
cord-310847-63gh2tg4	41	26	not	not	RB
cord-310847-63gh2tg4	41	27	too	too	RB
cord-310847-63gh2tg4	41	28	high	high	JJ
cord-310847-63gh2tg4	41	29	,	,	,
cord-310847-63gh2tg4	41	30	it	-PRON-	PRP
cord-310847-63gh2tg4	41	31	is	be	VBZ
cord-310847-63gh2tg4	41	32	important	important	JJ
cord-310847-63gh2tg4	41	33	to	to	TO
cord-310847-63gh2tg4	41	34	remember	remember	VB
cord-310847-63gh2tg4	41	35	that	that	IN
cord-310847-63gh2tg4	41	36	increasing	increase	VBG
cord-310847-63gh2tg4	41	37	the	the	DT
cord-310847-63gh2tg4	41	38	stability	stability	NN
cord-310847-63gh2tg4	41	39	of	of	IN
cord-310847-63gh2tg4	41	40	the	the	DT
cord-310847-63gh2tg4	41	41	bound	bind	VBN
cord-310847-63gh2tg4	41	42	conformation	conformation	NN
cord-310847-63gh2tg4	41	43	does	do	VBZ
cord-310847-63gh2tg4	41	44	not	not	RB
cord-310847-63gh2tg4	41	45	necessarily	necessarily	RB
cord-310847-63gh2tg4	41	46	enhance	enhance	VB
cord-310847-63gh2tg4	41	47	the	the	DT
cord-310847-63gh2tg4	41	48	binding	bind	VBG
cord-310847-63gh2tg4	41	49	affinity	affinity	NN
cord-310847-63gh2tg4	41	50	.	.	.
cord-310847-63gh2tg4	42	1	23	23	CD
cord-310847-63gh2tg4	43	1	Another	another	DT
cord-310847-63gh2tg4	43	2	important	important	JJ
cord-310847-63gh2tg4	43	3	feature	feature	NN
cord-310847-63gh2tg4	43	4	of	of	IN
cord-310847-63gh2tg4	43	5	the	the	DT
cord-310847-63gh2tg4	43	6	disorder	disorder	NN
cord-310847-63gh2tg4	43	7	-	-	HYPH
cord-310847-63gh2tg4	43	8	based	base	VBN
cord-310847-63gh2tg4	43	9	interactions	interaction	NNS
cord-310847-63gh2tg4	43	10	is	be	VBZ
cord-310847-63gh2tg4	43	11	their	-PRON-	PRP$
cord-310847-63gh2tg4	43	12	increased	increase	VBN
cord-310847-63gh2tg4	43	13	speed	speed	NN
cord-310847-63gh2tg4	43	14	due	due	IN
cord-310847-63gh2tg4	43	15	to	to	IN
cord-310847-63gh2tg4	43	16	the	the	DT
cord-310847-63gh2tg4	43	17	greater	great	JJR
cord-310847-63gh2tg4	43	18	capture	capture	NN
cord-310847-63gh2tg4	43	19	radius	radius	NN
cord-310847-63gh2tg4	43	20	and	and	CC
cord-310847-63gh2tg4	43	21	the	the	DT
cord-310847-63gh2tg4	43	22	ability	ability	NN
cord-310847-63gh2tg4	43	23	to	to	TO
cord-310847-63gh2tg4	43	24	spatially	spatially	RB
cord-310847-63gh2tg4	43	25	search	search	VB
cord-310847-63gh2tg4	43	26	through	through	IN
cord-310847-63gh2tg4	43	27	interaction	interaction	NN
cord-310847-63gh2tg4	43	28	space	space	NN
cord-310847-63gh2tg4	43	29	(	(	-LRB-
cord-310847-63gh2tg4	43	30	the	the	DT
cord-310847-63gh2tg4	43	31	so	so	RB
cord-310847-63gh2tg4	43	32	-	-	HYPH
cord-310847-63gh2tg4	43	33	called	call	VBN
cord-310847-63gh2tg4	43	34	"	"	``
cord-310847-63gh2tg4	43	35	fly	fly	NN
cord-310847-63gh2tg4	43	36	-	-	HYPH
cord-310847-63gh2tg4	43	37	casting	cast	VBG
cord-310847-63gh2tg4	43	38	"	"	''
cord-310847-63gh2tg4	43	39	mechanism	mechanism	NN
cord-310847-63gh2tg4	43	40	)	)	-RRB-
cord-310847-63gh2tg4	43	41	43	43	CD
cord-310847-63gh2tg4	43	42	and	and	CC
cord-310847-63gh2tg4	43	43	to	to	IN
cord-310847-63gh2tg4	43	44	the	the	DT
cord-310847-63gh2tg4	43	45	fact	fact	NN
cord-310847-63gh2tg4	43	46	that	that	IN
cord-310847-63gh2tg4	43	47	fewer	few	JJR
cord-310847-63gh2tg4	43	48	encounter	encounter	NN
cord-310847-63gh2tg4	43	49	events	event	NNS
cord-310847-63gh2tg4	43	50	are	be	VBP
cord-310847-63gh2tg4	43	51	required	require	VBN
cord-310847-63gh2tg4	43	52	for	for	IN
cord-310847-63gh2tg4	43	53	the	the	DT
cord-310847-63gh2tg4	43	54	binding	binding	NN
cord-310847-63gh2tg4	43	55	because	because	IN
cord-310847-63gh2tg4	43	56	of	of	IN
cord-310847-63gh2tg4	43	57	lack	lack	NN
cord-310847-63gh2tg4	43	58	of	of	IN
cord-310847-63gh2tg4	43	59	orientational	orientational	JJ
cord-310847-63gh2tg4	43	60	restrains	restrain	NNS
cord-310847-63gh2tg4	43	61	.	.	.
cord-310847-63gh2tg4	44	1	44	44	CD
cord-310847-63gh2tg4	45	1	Linking	link	VBG
cord-310847-63gh2tg4	45	2	all	all	PDT
cord-310847-63gh2tg4	45	3	these	these	DT
cord-310847-63gh2tg4	45	4	form	form	NN
cord-310847-63gh2tg4	45	5	at	at	IN
cord-310847-63gh2tg4	45	6	pHs	pHs	NNP
cord-310847-63gh2tg4	45	7	greater	great	JJR
cord-310847-63gh2tg4	45	8	than	than	IN
cord-310847-63gh2tg4	45	9	its	-PRON-	PRP$
cord-310847-63gh2tg4	45	10	pK	pK	NNP
cord-310847-63gh2tg4	46	1	a	a	LS
cord-310847-63gh2tg4	46	2	4.6	4.6	CD
cord-310847-63gh2tg4	46	3	(	(	-LRB-
cord-310847-63gh2tg4	46	4	and	and	CC
cord-310847-63gh2tg4	46	5	thus	thus	RB
cord-310847-63gh2tg4	46	6	Glu	Glu	NNP
cord-310847-63gh2tg4	46	7	is	be	VBZ
cord-310847-63gh2tg4	46	8	negatively	negatively	RB
cord-310847-63gh2tg4	46	9	charged	charge	VBN
cord-310847-63gh2tg4	46	10	at	at	IN
cord-310847-63gh2tg4	46	11	the	the	DT
cord-310847-63gh2tg4	46	12	physiological	physiological	JJ
cord-310847-63gh2tg4	46	13	pH	ph	NN
cord-310847-63gh2tg4	46	14	ranging	range	VBG
cord-310847-63gh2tg4	46	15	from	from	IN
cord-310847-63gh2tg4	46	16	7	7	CD
cord-310847-63gh2tg4	46	17	.	.	.
cord-310847-63gh2tg4	47	1	35	35	CD
cord-310847-63gh2tg4	47	2	-	-	SYM
cord-310847-63gh2tg4	47	3	7.45	7.45	CD
cord-310847-63gh2tg4	47	4	)	)	-RRB-
cord-310847-63gh2tg4	47	5	.	.	.
cord-310847-63gh2tg4	48	1	Therefore	therefore	RB
cord-310847-63gh2tg4	48	2	,	,	,
cord-310847-63gh2tg4	48	3	glutamic	glutamic	NN
cord-310847-63gh2tg4	48	4	acid	acid	NN
cord-310847-63gh2tg4	48	5	is	be	VBZ
cord-310847-63gh2tg4	48	6	one	one	CD
cord-310847-63gh2tg4	48	7	of	of	IN
cord-310847-63gh2tg4	48	8	two	two	CD
cord-310847-63gh2tg4	48	9	acidic	acidic	JJ
cord-310847-63gh2tg4	48	10	amino	amino	NN
cord-310847-63gh2tg4	48	11	acids	acid	NNS
cord-310847-63gh2tg4	48	12	found	find	VBN
cord-310847-63gh2tg4	48	13	in	in	IN
cord-310847-63gh2tg4	48	14	proteins	protein	NNS
cord-310847-63gh2tg4	48	15	that	that	WDT
cord-310847-63gh2tg4	48	16	play	play	VBP
cord-310847-63gh2tg4	48	17	important	important	JJ
cord-310847-63gh2tg4	48	18	roles	role	NNS
cord-310847-63gh2tg4	48	19	as	as	IN
cord-310847-63gh2tg4	48	20	general	general	JJ
cord-310847-63gh2tg4	48	21	acids	acid	NNS
cord-310847-63gh2tg4	48	22	in	in	IN
cord-310847-63gh2tg4	48	23	enzyme	enzyme	NN
cord-310847-63gh2tg4	48	24	active	active	JJ
cord-310847-63gh2tg4	48	25	centers	center	NNS
cord-310847-63gh2tg4	48	26	,	,	,
cord-310847-63gh2tg4	48	27	as	as	RB
cord-310847-63gh2tg4	48	28	well	well	RB
cord-310847-63gh2tg4	48	29	as	as	IN
cord-310847-63gh2tg4	48	30	in	in	IN
cord-310847-63gh2tg4	48	31	maintaining	maintain	VBG
cord-310847-63gh2tg4	48	32	the	the	DT
cord-310847-63gh2tg4	48	33	solubility	solubility	NN
cord-310847-63gh2tg4	48	34	and	and	CC
cord-310847-63gh2tg4	48	35	ionic	ionic	JJ
cord-310847-63gh2tg4	48	36	character	character	NN
cord-310847-63gh2tg4	48	37	of	of	IN
cord-310847-63gh2tg4	48	38	proteins	protein	NNS
cord-310847-63gh2tg4	48	39	.	.	.
cord-310847-63gh2tg4	49	1	In	in	IN
cord-310847-63gh2tg4	49	2	fact	fact	NN
cord-310847-63gh2tg4	49	3	,	,	,
cord-310847-63gh2tg4	49	4	glutamic	glutamic	NN
cord-310847-63gh2tg4	49	5	acid	acid	NN
cord-310847-63gh2tg4	49	6	residue	residue	NN
cord-310847-63gh2tg4	49	7	has	have	VBZ
cord-310847-63gh2tg4	49	8	a	a	DT
cord-310847-63gh2tg4	49	9	nonpolar	nonpolar	JJ
cord-310847-63gh2tg4	49	10	surface	surface	NN
cord-310847-63gh2tg4	49	11	of	of	IN
cord-310847-63gh2tg4	49	12	69	69	CD
cord-310847-63gh2tg4	49	13	Å	å	NN
cord-310847-63gh2tg4	49	14	2	2	CD
cord-310847-63gh2tg4	49	15	,	,	,
cord-310847-63gh2tg4	49	16	and	and	CC
cord-310847-63gh2tg4	49	17	the	the	DT
cord-310847-63gh2tg4	49	18	estimated	estimate	VBN
cord-310847-63gh2tg4	49	19	hydrophobic	hydrophobic	JJ
cord-310847-63gh2tg4	49	20	effect	effect	NN
cord-310847-63gh2tg4	49	21	associated	associate	VBN
cord-310847-63gh2tg4	49	22	with	with	IN
cord-310847-63gh2tg4	49	23	the	the	DT
cord-310847-63gh2tg4	49	24	burial	burial	NN
cord-310847-63gh2tg4	49	25	of	of	IN
cord-310847-63gh2tg4	49	26	this	this	DT
cord-310847-63gh2tg4	49	27	residue	residue	NN
cord-310847-63gh2tg4	49	28	is	be	VBZ
cord-310847-63gh2tg4	49	29	1.74	1.74	CD
cord-310847-63gh2tg4	49	30	kcal	kcal	NNP
cord-310847-63gh2tg4	49	31	/	/	SYM
cord-310847-63gh2tg4	49	32	mol	mol	NN
cord-310847-63gh2tg4	49	33	.	.	.
cord-310847-63gh2tg4	50	1	52	52	CD
cord-310847-63gh2tg4	51	1	In	in	IN
cord-310847-63gh2tg4	51	2	ordered	order	VBN
cord-310847-63gh2tg4	51	3	proteins	protein	NNS
cord-310847-63gh2tg4	51	4	,	,	,
cord-310847-63gh2tg4	51	5	glutamic	glutamic	JJ
cord-310847-63gh2tg4	51	6	acids	acid	NNS
cord-310847-63gh2tg4	51	7	are	be	VBP
cord-310847-63gh2tg4	51	8	predominantly	predominantly	RB
cord-310847-63gh2tg4	51	9	located	locate	VBN
cord-310847-63gh2tg4	51	10	on	on	IN
cord-310847-63gh2tg4	51	11	protein	protein	NN
cord-310847-63gh2tg4	51	12	surface	surface	NN
cord-310847-63gh2tg4	51	13	so	so	IN
cord-310847-63gh2tg4	51	14	that	that	IN
cord-310847-63gh2tg4	51	15	they	-PRON-	PRP
cord-310847-63gh2tg4	51	16	have	have	VBP
cord-310847-63gh2tg4	51	17	access	access	NN
cord-310847-63gh2tg4	51	18	to	to	IN
cord-310847-63gh2tg4	51	19	the	the	DT
cord-310847-63gh2tg4	51	20	solvent	solvent	NN
cord-310847-63gh2tg4	51	21	.	.	.
cord-310847-63gh2tg4	52	1	In	in	IN
cord-310847-63gh2tg4	52	2	fact	fact	NN
cord-310847-63gh2tg4	52	3	,	,	,
cord-310847-63gh2tg4	52	4	93	93	CD
cord-310847-63gh2tg4	52	5	%	%	NN
cord-310847-63gh2tg4	52	6	of	of	IN
cord-310847-63gh2tg4	52	7	glutamic	glutamic	NN
cord-310847-63gh2tg4	52	8	acids	acid	NNS
cord-310847-63gh2tg4	52	9	in	in	IN
cord-310847-63gh2tg4	52	10	known	know	VBN
cord-310847-63gh2tg4	52	11	structures	structure	NNS
cord-310847-63gh2tg4	52	12	of	of	IN
cord-310847-63gh2tg4	52	13	folded	fold	VBN
cord-310847-63gh2tg4	52	14	proteins	protein	NNS
cord-310847-63gh2tg4	52	15	are	be	VBP
cord-310847-63gh2tg4	52	16	classified	classify	VBN
cord-310847-63gh2tg4	52	17	as	as	IN
cord-310847-63gh2tg4	52	18	exposed	expose	VBN
cord-310847-63gh2tg4	52	19	since	since	IN
cord-310847-63gh2tg4	52	20	they	-PRON-	PRP
cord-310847-63gh2tg4	52	21	have	have	VBP
cord-310847-63gh2tg4	52	22	solvent	solvent	NN
cord-310847-63gh2tg4	52	23	exposed	expose	VBN
cord-310847-63gh2tg4	52	24	areas	area	NNS
cord-310847-63gh2tg4	52	25	of	of	IN
cord-310847-63gh2tg4	52	26	>	>	$
cord-310847-63gh2tg4	52	27	30	30	CD
cord-310847-63gh2tg4	52	28	Å	å	NN
cord-310847-63gh2tg4	52	29	2	2	CD
cord-310847-63gh2tg4	52	30	,	,	,
cord-310847-63gh2tg4	52	31	and	and	CC
cord-310847-63gh2tg4	53	1	only	only	RB
cord-310847-63gh2tg4	53	2	4	4	CD
cord-310847-63gh2tg4	53	3	%	%	NN
cord-310847-63gh2tg4	53	4	of	of	IN
cord-310847-63gh2tg4	53	5	glutamic	glutamic	NN
cord-310847-63gh2tg4	53	6	acids	acid	NNS
cord-310847-63gh2tg4	53	7	in	in	IN
cord-310847-63gh2tg4	53	8	folded	fold	VBN
cord-310847-63gh2tg4	53	9	proteins	protein	NNS
cord-310847-63gh2tg4	53	10	possess	possess	VBP
cord-310847-63gh2tg4	53	11	solvent	solvent	NN
cord-310847-63gh2tg4	53	12	exposed	expose	VBN
cord-310847-63gh2tg4	53	13	areas	area	NNS
cord-310847-63gh2tg4	53	14	of	of	IN
cord-310847-63gh2tg4	53	15	<	<	NNP
cord-310847-63gh2tg4	53	16	10	10	CD
cord-310847-63gh2tg4	53	17	Å	å	NN
cord-310847-63gh2tg4	53	18	2	2	CD
cord-310847-63gh2tg4	53	19	and	and	CC
cord-310847-63gh2tg4	53	20	therefore	therefore	RB
cord-310847-63gh2tg4	53	21	are	be	VBP
cord-310847-63gh2tg4	53	22	buried	bury	VBN
cord-310847-63gh2tg4	53	23	.	.	.
cord-310847-63gh2tg4	54	1	53	53	CD
cord-310847-63gh2tg4	55	1	The	the	DT
cord-310847-63gh2tg4	55	2	carboxylate	carboxylate	NNP
cord-310847-63gh2tg4	55	3	anions	anion	NNS
cord-310847-63gh2tg4	55	4	and	and	CC
cord-310847-63gh2tg4	55	5	salts	salt	NNS
cord-310847-63gh2tg4	55	6	of	of	IN
cord-310847-63gh2tg4	55	7	glutamic	glutamic	NN
cord-310847-63gh2tg4	55	8	acid	acid	NN
cord-310847-63gh2tg4	55	9	are	be	VBP
cord-310847-63gh2tg4	55	10	known	know	VBN
cord-310847-63gh2tg4	55	11	as	as	IN
cord-310847-63gh2tg4	55	12	glutamates	glutamate	NNS
cord-310847-63gh2tg4	55	13	.	.	.
cord-310847-63gh2tg4	56	1	Glutamic	glutamic	NN
cord-310847-63gh2tg4	56	2	acid	acid	NN
cord-310847-63gh2tg4	56	3	is	be	VBZ
cord-310847-63gh2tg4	56	4	one	one	CD
cord-310847-63gh2tg4	56	5	of	of	IN
cord-310847-63gh2tg4	56	6	the	the	DT
cord-310847-63gh2tg4	56	7	most	most	RBS
cord-310847-63gh2tg4	56	8	common	common	JJ
cord-310847-63gh2tg4	56	9	natural	natural	JJ
cord-310847-63gh2tg4	56	10	amino	amino	NN
cord-310847-63gh2tg4	56	11	acids	acid	NNS
cord-310847-63gh2tg4	56	12	and	and	CC
cord-310847-63gh2tg4	56	13	the	the	DT
cord-310847-63gh2tg4	56	14	most	most	RBS
cord-310847-63gh2tg4	56	15	abundant	abundant	JJ
cord-310847-63gh2tg4	56	16	amino	amino	NN
cord-310847-63gh2tg4	56	17	acid	acid	NN
cord-310847-63gh2tg4	56	18	in	in	IN
cord-310847-63gh2tg4	56	19	the	the	DT
cord-310847-63gh2tg4	56	20	diet	diet	NN
cord-310847-63gh2tg4	56	21	.	.	.
cord-310847-63gh2tg4	57	1	Besides	besides	IN
cord-310847-63gh2tg4	57	2	being	be	VBG
cord-310847-63gh2tg4	57	3	an	an	DT
cord-310847-63gh2tg4	57	4	important	important	JJ
cord-310847-63gh2tg4	57	5	component	component	NN
cord-310847-63gh2tg4	57	6	of	of	IN
cord-310847-63gh2tg4	57	7	proteins	protein	NNS
cord-310847-63gh2tg4	57	8	and	and	CC
cord-310847-63gh2tg4	57	9	polypeptides	polypeptide	NNS
cord-310847-63gh2tg4	57	10	(	(	-LRB-
cord-310847-63gh2tg4	57	11	see	see	VB
cord-310847-63gh2tg4	57	12	below	below	RB
cord-310847-63gh2tg4	57	13	)	)	-RRB-
cord-310847-63gh2tg4	57	14	,	,	,
cord-310847-63gh2tg4	57	15	being	be	VBG
cord-310847-63gh2tg4	57	16	a	a	DT
cord-310847-63gh2tg4	57	17	substrate	substrate	NN
cord-310847-63gh2tg4	57	18	for	for	IN
cord-310847-63gh2tg4	57	19	the	the	DT
cord-310847-63gh2tg4	57	20	production	production	NN
cord-310847-63gh2tg4	57	21	of	of	IN
cord-310847-63gh2tg4	57	22	the	the	DT
cord-310847-63gh2tg4	57	23	Krebscycle	Krebscycle	NNP
cord-310847-63gh2tg4	57	24	-	-	HYPH
cord-310847-63gh2tg4	57	25	related	relate	VBN
cord-310847-63gh2tg4	57	26	α	α	NN
cord-310847-63gh2tg4	57	27	-	-	HYPH
cord-310847-63gh2tg4	57	28	ketoglutarate	ketoglutarate	NN
cord-310847-63gh2tg4	57	29	intermediate	intermediate	NN
cord-310847-63gh2tg4	57	30	,	,	,
cord-310847-63gh2tg4	57	31	glutamine	glutamine	NN
cord-310847-63gh2tg4	57	32	and	and	CC
cord-310847-63gh2tg4	57	33	proline	proline	NN
cord-310847-63gh2tg4	57	34	,	,	,
cord-310847-63gh2tg4	57	35	and	and	CC
cord-310847-63gh2tg4	57	36	being	be	VBG
cord-310847-63gh2tg4	57	37	the	the	DT
cord-310847-63gh2tg4	57	38	precursor	precursor	NN
cord-310847-63gh2tg4	57	39	for	for	IN
cord-310847-63gh2tg4	57	40	the	the	DT
cord-310847-63gh2tg4	57	41	synthesis	synthesis	NN
cord-310847-63gh2tg4	57	42	of	of	IN
cord-310847-63gh2tg4	57	43	the	the	DT
cord-310847-63gh2tg4	57	44	inhibitory	inhibitory	JJ
cord-310847-63gh2tg4	57	45	γ	γ	NN
cord-310847-63gh2tg4	57	46	-	-	HYPH
cord-310847-63gh2tg4	57	47	aminobutyric	aminobutyric	NN
cord-310847-63gh2tg4	57	48	acid	acid	NN
cord-310847-63gh2tg4	57	49	(	(	-LRB-
cord-310847-63gh2tg4	57	50	GABA	GABA	NNP
cord-310847-63gh2tg4	57	51	)	)	-RRB-
cord-310847-63gh2tg4	57	52	in	in	IN
cord-310847-63gh2tg4	57	53	GABA	GABA	NNP
cord-310847-63gh2tg4	57	54	-	-	HYPH
cord-310847-63gh2tg4	57	55	ergic	ergic	JJ
cord-310847-63gh2tg4	57	56	neurons	neuron	NNS
cord-310847-63gh2tg4	57	57	,	,	,
cord-310847-63gh2tg4	57	58	glutamate	glutamate	NN
cord-310847-63gh2tg4	57	59	is	be	VBZ
cord-310847-63gh2tg4	57	60	the	the	DT
cord-310847-63gh2tg4	57	61	principal	principal	JJ
cord-310847-63gh2tg4	57	62	excitatory	excitatory	JJ
cord-310847-63gh2tg4	57	63	neurotransmitter	neurotransmitter	NN
cord-310847-63gh2tg4	57	64	within	within	IN
cord-310847-63gh2tg4	57	65	the	the	DT
cord-310847-63gh2tg4	57	66	vertebrate	vertebrate	JJ
cord-310847-63gh2tg4	57	67	nervous	nervous	JJ
cord-310847-63gh2tg4	57	68	system	system	NN
cord-310847-63gh2tg4	57	69	.	.	.
cord-310847-63gh2tg4	58	1	54	54	CD
cord-310847-63gh2tg4	59	1	In	in	IN
cord-310847-63gh2tg4	59	2	fact	fact	NN
cord-310847-63gh2tg4	59	3	,	,	,
cord-310847-63gh2tg4	59	4	glutamate	glutamate	NN
cord-310847-63gh2tg4	59	5	is	be	VBZ
cord-310847-63gh2tg4	59	6	known	know	VBN
cord-310847-63gh2tg4	59	7	to	to	TO
cord-310847-63gh2tg4	59	8	act	act	VB
cord-310847-63gh2tg4	59	9	on	on	IN
cord-310847-63gh2tg4	59	10	several	several	JJ
cord-310847-63gh2tg4	59	11	different	different	JJ
cord-310847-63gh2tg4	59	12	types	type	NNS
cord-310847-63gh2tg4	59	13	of	of	IN
cord-310847-63gh2tg4	59	14	receptors	receptor	NNS
cord-310847-63gh2tg4	59	15	and	and	CC
cord-310847-63gh2tg4	59	16	has	have	VBZ
cord-310847-63gh2tg4	59	17	excitatory	excitatory	JJ
cord-310847-63gh2tg4	59	18	effects	effect	NNS
cord-310847-63gh2tg4	59	19	at	at	IN
cord-310847-63gh2tg4	59	20	ionotropic	ionotropic	JJ
cord-310847-63gh2tg4	59	21	receptors	receptor	NNS
cord-310847-63gh2tg4	59	22	[	[	-LRB-
cord-310847-63gh2tg4	59	23	such	such	JJ
cord-310847-63gh2tg4	59	24	as	as	IN
cord-310847-63gh2tg4	59	25	N	n	CD
cord-310847-63gh2tg4	59	26	-	-	HYPH
cord-310847-63gh2tg4	59	27	methyl	methyl	NN
cord-310847-63gh2tg4	59	28	-	-	HYPH
cord-310847-63gh2tg4	59	29	D	d	NN
cord-310847-63gh2tg4	59	30	-	-	HYPH
cord-310847-63gh2tg4	59	31	aspartate	aspartate	NN
cord-310847-63gh2tg4	59	32	(	(	-LRB-
cord-310847-63gh2tg4	59	33	NMDA	NMDA	NNP
cord-310847-63gh2tg4	59	34	)	)	-RRB-
cord-310847-63gh2tg4	59	35	,	,	,
cord-310847-63gh2tg4	59	36	α	α	NN
cord-310847-63gh2tg4	59	37	-	-	HYPH
cord-310847-63gh2tg4	59	38	amino-3-hydroxy-5-methyl-4-isoxazolepropionic	amino-3-hydroxy-5-methyl-4-isoxazolepropionic	JJ
cord-310847-63gh2tg4	59	39	acid	acid	NN
cord-310847-63gh2tg4	59	40	(	(	-LRB-
cord-310847-63gh2tg4	59	41	AMPA	AMPA	NNP
cord-310847-63gh2tg4	59	42	)	)	-RRB-
cord-310847-63gh2tg4	59	43	,	,	,
cord-310847-63gh2tg4	59	44	and	and	CC
cord-310847-63gh2tg4	59	45	kainite	kainite	NNP
cord-310847-63gh2tg4	59	46	,	,	,
cord-310847-63gh2tg4	59	47	which	which	WDT
cord-310847-63gh2tg4	59	48	all	all	DT
cord-310847-63gh2tg4	59	49	incorporate	incorporate	VBP
cord-310847-63gh2tg4	59	50	ion	ion	NN
cord-310847-63gh2tg4	59	51	channels	channel	NNS
cord-310847-63gh2tg4	59	52	that	that	WDT
cord-310847-63gh2tg4	59	53	are	be	VBP
cord-310847-63gh2tg4	59	54	permeable	permeable	JJ
cord-310847-63gh2tg4	59	55	to	to	IN
cord-310847-63gh2tg4	59	56	cations	cation	NNS
cord-310847-63gh2tg4	59	57	]	]	-RRB-
cord-310847-63gh2tg4	59	58	and	and	CC
cord-310847-63gh2tg4	59	59	modulatory	modulatory	JJ
cord-310847-63gh2tg4	59	60	effects	effect	NNS
cord-310847-63gh2tg4	59	61	at	at	IN
cord-310847-63gh2tg4	59	62	metabotropic	metabotropic	JJ
cord-310847-63gh2tg4	59	63	receptors	receptor	NNS
cord-310847-63gh2tg4	59	64	[	[	-LRB-
cord-310847-63gh2tg4	59	65	which	which	WDT
cord-310847-63gh2tg4	59	66	are	be	VBP
cord-310847-63gh2tg4	59	67	G	g	NN
cord-310847-63gh2tg4	59	68	protein	protein	NN
cord-310847-63gh2tg4	59	69	-	-	HYPH
cord-310847-63gh2tg4	59	70	coupled	couple	VBN
cord-310847-63gh2tg4	59	71	glutamate	glutamate	NN
cord-310847-63gh2tg4	59	72	receptors	receptor	NNS
cord-310847-63gh2tg4	59	73	(	(	-LRB-
cord-310847-63gh2tg4	59	74	mGluR	mglur	FW
cord-310847-63gh2tg4	59	75	)	)	-RRB-
cord-310847-63gh2tg4	59	76	that	that	WDT
cord-310847-63gh2tg4	59	77	modify	modify	VBP
cord-310847-63gh2tg4	59	78	neuronal	neuronal	JJ
cord-310847-63gh2tg4	59	79	and	and	CC
cord-310847-63gh2tg4	59	80	glial	glial	JJ
cord-310847-63gh2tg4	59	81	excitability	excitability	NN
cord-310847-63gh2tg4	59	82	through	through	IN
cord-310847-63gh2tg4	59	83	G	g	NN
cord-310847-63gh2tg4	59	84	protein	protein	NN
cord-310847-63gh2tg4	59	85	subunits	subunit	NNS
cord-310847-63gh2tg4	59	86	acting	act	VBG
cord-310847-63gh2tg4	59	87	on	on	IN
cord-310847-63gh2tg4	59	88	membrane	membrane	NN
cord-310847-63gh2tg4	59	89	ion	ion	NN
cord-310847-63gh2tg4	59	90	channels	channel	NNS
cord-310847-63gh2tg4	59	91	and	and	CC
cord-310847-63gh2tg4	59	92	second	second	JJ
cord-310847-63gh2tg4	59	93	messengers	messenger	NNS
cord-310847-63gh2tg4	59	94	such	such	JJ
cord-310847-63gh2tg4	59	95	as	as	IN
cord-310847-63gh2tg4	59	96	diacylglycerol	diacylglycerol	NN
cord-310847-63gh2tg4	59	97	and	and	CC
cord-310847-63gh2tg4	59	98	cAMP	camp	NN
cord-310847-63gh2tg4	59	99	]	]	-RRB-
cord-310847-63gh2tg4	59	100	.	.	.
cord-310847-63gh2tg4	60	1	54	54	CD
cord-310847-63gh2tg4	61	1	At	at	IN
cord-310847-63gh2tg4	61	2	chemical	chemical	JJ
cord-310847-63gh2tg4	61	3	synapses	synapsis	NNS
cord-310847-63gh2tg4	61	4	of	of	IN
cord-310847-63gh2tg4	61	5	the	the	DT
cord-310847-63gh2tg4	61	6	glutamatergic	glutamatergic	JJ
cord-310847-63gh2tg4	61	7	neurons	neuron	NNS
cord-310847-63gh2tg4	61	8	,	,	,
cord-310847-63gh2tg4	61	9	glutamate	glutamate	NN
cord-310847-63gh2tg4	61	10	is	be	VBZ
cord-310847-63gh2tg4	61	11	stored	store	VBN
cord-310847-63gh2tg4	61	12	in	in	IN
cord-310847-63gh2tg4	61	13	vesicles	vesicle	NNS
cord-310847-63gh2tg4	61	14	and	and	CC
cord-310847-63gh2tg4	61	15	is	be	VBZ
cord-310847-63gh2tg4	61	16	released	release	VBN
cord-310847-63gh2tg4	61	17	from	from	IN
cord-310847-63gh2tg4	61	18	the	the	DT
cord-310847-63gh2tg4	61	19	pre	pre	JJ
cord-310847-63gh2tg4	61	20	-	-	JJ
cord-310847-63gh2tg4	61	21	synaptic	synaptic	JJ
cord-310847-63gh2tg4	61	22	cell	cell	NN
cord-310847-63gh2tg4	61	23	by	by	IN
cord-310847-63gh2tg4	61	24	nerve	nerve	NN
cord-310847-63gh2tg4	61	25	impulses	impulse	NNS
cord-310847-63gh2tg4	61	26	.	.	.
cord-310847-63gh2tg4	62	1	In	in	IN
cord-310847-63gh2tg4	62	2	the	the	DT
cord-310847-63gh2tg4	62	3	opposing	oppose	VBG
cord-310847-63gh2tg4	62	4	post	post	JJ
cord-310847-63gh2tg4	62	5	-	-	JJ
cord-310847-63gh2tg4	62	6	synaptic	synaptic	JJ
cord-310847-63gh2tg4	62	7	cell	cell	NN
cord-310847-63gh2tg4	62	8	,	,	,
cord-310847-63gh2tg4	62	9	binding	bind	VBG
cord-310847-63gh2tg4	62	10	of	of	IN
cord-310847-63gh2tg4	62	11	glutamate	glutamate	NN
cord-310847-63gh2tg4	62	12	lead	lead	NN
cord-310847-63gh2tg4	62	13	to	to	IN
cord-310847-63gh2tg4	62	14	activation	activation	NN
cord-310847-63gh2tg4	62	15	of	of	IN
cord-310847-63gh2tg4	62	16	specific	specific	JJ
cord-310847-63gh2tg4	62	17	glutamate	glutamate	NN
cord-310847-63gh2tg4	62	18	receptors	receptor	NNS
cord-310847-63gh2tg4	62	19	such	such	JJ
cord-310847-63gh2tg4	62	20	as	as	IN
cord-310847-63gh2tg4	62	21	NMDA	NMDA	NNP
cord-310847-63gh2tg4	62	22	or	or	CC
cord-310847-63gh2tg4	62	23	AMPA	AMPA	NNP
cord-310847-63gh2tg4	62	24	.	.	.
cord-310847-63gh2tg4	63	1	Glutamate	glutamate	NN
cord-310847-63gh2tg4	63	2	plays	play	VBZ
cord-310847-63gh2tg4	63	3	an	an	DT
cord-310847-63gh2tg4	63	4	important	important	JJ
cord-310847-63gh2tg4	63	5	role	role	NN
cord-310847-63gh2tg4	63	6	in	in	IN
cord-310847-63gh2tg4	63	7	synaptic	synaptic	JJ
cord-310847-63gh2tg4	63	8	plasticity	plasticity	NN
cord-310847-63gh2tg4	63	9	in	in	IN
cord-310847-63gh2tg4	63	10	the	the	DT
cord-310847-63gh2tg4	63	11	brain	brain	NN
cord-310847-63gh2tg4	63	12	and	and	CC
cord-310847-63gh2tg4	63	13	is	be	VBZ
cord-310847-63gh2tg4	63	14	involved	involve	VBN
cord-310847-63gh2tg4	63	15	in	in	IN
cord-310847-63gh2tg4	63	16	various	various	JJ
cord-310847-63gh2tg4	63	17	cognitive	cognitive	JJ
cord-310847-63gh2tg4	63	18	functions	function	NNS
cord-310847-63gh2tg4	63	19	,	,	,
cord-310847-63gh2tg4	63	20	such	such	JJ
cord-310847-63gh2tg4	63	21	as	as	IN
cord-310847-63gh2tg4	63	22	learning	learning	NN
cord-310847-63gh2tg4	63	23	and	and	CC
cord-310847-63gh2tg4	63	24	memory	memory	NN
cord-310847-63gh2tg4	63	25	.	.	.
cord-310847-63gh2tg4	64	1	55	55	CD
cord-310847-63gh2tg4	65	1	In	in	IN
cord-310847-63gh2tg4	65	2	fact	fact	NN
cord-310847-63gh2tg4	65	3	,	,	,
cord-310847-63gh2tg4	65	4	long	long	JJ
cord-310847-63gh2tg4	65	5	-	-	HYPH
cord-310847-63gh2tg4	65	6	term	term	NN
cord-310847-63gh2tg4	65	7	potentiation	potentiation	NN
cord-310847-63gh2tg4	65	8	(	(	-LRB-
cord-310847-63gh2tg4	65	9	one	one	CD
cord-310847-63gh2tg4	65	10	of	of	IN
cord-310847-63gh2tg4	65	11	the	the	DT
cord-310847-63gh2tg4	65	12	plasticity	plasticity	NN
cord-310847-63gh2tg4	65	13	forms	form	NNS
cord-310847-63gh2tg4	65	14	)	)	-RRB-
cord-310847-63gh2tg4	65	15	takes	take	VBZ
cord-310847-63gh2tg4	65	16	place	place	NN
cord-310847-63gh2tg4	65	17	at	at	IN
cord-310847-63gh2tg4	65	18	glutamatergic	glutamatergic	JJ
cord-310847-63gh2tg4	65	19	synapses	synapsis	NNS
cord-310847-63gh2tg4	65	20	in	in	IN
cord-310847-63gh2tg4	65	21	the	the	DT
cord-310847-63gh2tg4	65	22	neocortex	neocortex	NN
cord-310847-63gh2tg4	65	23	,	,	,
cord-310847-63gh2tg4	65	24	hippocampus	hippocampus	NN
cord-310847-63gh2tg4	65	25	and	and	CC
cord-310847-63gh2tg4	65	26	other	other	JJ
cord-310847-63gh2tg4	65	27	parts	part	NNS
cord-310847-63gh2tg4	65	28	of	of	IN
cord-310847-63gh2tg4	65	29	the	the	DT
cord-310847-63gh2tg4	65	30	brain	brain	NN
cord-310847-63gh2tg4	65	31	.	.	.
cord-310847-63gh2tg4	66	1	55	55	CD
cord-310847-63gh2tg4	67	1	Another	another	DT
cord-310847-63gh2tg4	67	2	important	important	JJ
cord-310847-63gh2tg4	67	3	role	role	NN
cord-310847-63gh2tg4	67	4	of	of	IN
cord-310847-63gh2tg4	67	5	glutamate	glutamate	NN
cord-310847-63gh2tg4	67	6	is	be	VBZ
cord-310847-63gh2tg4	67	7	its	-PRON-	PRP$
cord-310847-63gh2tg4	67	8	ability	ability	NN
cord-310847-63gh2tg4	67	9	to	to	TO
cord-310847-63gh2tg4	67	10	generate	generate	VB
cord-310847-63gh2tg4	67	11	volume	volume	NN
cord-310847-63gh2tg4	67	12	transmission	transmission	NN
cord-310847-63gh2tg4	67	13	,	,	,
cord-310847-63gh2tg4	67	14	where	where	WRB
cord-310847-63gh2tg4	67	15	extrasynaptic	extrasynaptic	JJ
cord-310847-63gh2tg4	67	16	signaling	signaling	NN
cord-310847-63gh2tg4	67	17	is	be	VBZ
cord-310847-63gh2tg4	67	18	created	create	VBN
cord-310847-63gh2tg4	67	19	via	via	IN
cord-310847-63gh2tg4	67	20	the	the	DT
cord-310847-63gh2tg4	67	21	summation	summation	NN
cord-310847-63gh2tg4	67	22	of	of	IN
cord-310847-63gh2tg4	67	23	glutamate	glutamate	NN
cord-310847-63gh2tg4	67	24	released	release	VBN
cord-310847-63gh2tg4	67	25	from	from	IN
cord-310847-63gh2tg4	67	26	a	a	DT
cord-310847-63gh2tg4	67	27	neighboring	neighbor	VBG
cord-310847-63gh2tg4	67	28	synapse	synapse	NN
cord-310847-63gh2tg4	67	29	.	.	.
cord-310847-63gh2tg4	68	1	56	56	CD
cord-310847-63gh2tg4	69	1	In	in	IN
cord-310847-63gh2tg4	69	2	addition	addition	NN
cord-310847-63gh2tg4	69	3	to	to	IN
cord-310847-63gh2tg4	69	4	glutamate	glutamate	NN
cord-310847-63gh2tg4	69	5	receptors	receptor	NNS
cord-310847-63gh2tg4	69	6	,	,	,
cord-310847-63gh2tg4	69	7	neuronal	neuronal	JJ
cord-310847-63gh2tg4	69	8	and	and	CC
cord-310847-63gh2tg4	69	9	glial	glial	JJ
cord-310847-63gh2tg4	69	10	membranes	membrane	NNS
cord-310847-63gh2tg4	69	11	contain	contain	VBP
cord-310847-63gh2tg4	69	12	glutamate	glutamate	NN
cord-310847-63gh2tg4	69	13	transporters	transporter	NNS
cord-310847-63gh2tg4	69	14	that	that	WDT
cord-310847-63gh2tg4	69	15	are	be	VBP
cord-310847-63gh2tg4	69	16	responsible	responsible	JJ
cord-310847-63gh2tg4	69	17	for	for	IN
cord-310847-63gh2tg4	69	18	rapid	rapid	JJ
cord-310847-63gh2tg4	69	19	remove	remove	NN
cord-310847-63gh2tg4	69	20	of	of	IN
cord-310847-63gh2tg4	69	21	glutamate	glutamate	NN
cord-310847-63gh2tg4	69	22	from	from	IN
cord-310847-63gh2tg4	69	23	extracellular	extracellular	JJ
cord-310847-63gh2tg4	69	24	space	space	NN
cord-310847-63gh2tg4	69	25	.	.	.
cord-310847-63gh2tg4	70	1	57	57	CD
cord-310847-63gh2tg4	71	1	Under	under	IN
cord-310847-63gh2tg4	71	2	stress	stress	NN
cord-310847-63gh2tg4	71	3	conditions	condition	NNS
cord-310847-63gh2tg4	71	4	(	(	-LRB-
cord-310847-63gh2tg4	71	5	such	such	JJ
cord-310847-63gh2tg4	71	6	as	as	IN
cord-310847-63gh2tg4	71	7	brain	brain	NN
cord-310847-63gh2tg4	71	8	injury	injury	NN
cord-310847-63gh2tg4	71	9	or	or	CC
cord-310847-63gh2tg4	71	10	disease	disease	NN
cord-310847-63gh2tg4	71	11	)	)	-RRB-
cord-310847-63gh2tg4	71	12	,	,	,
cord-310847-63gh2tg4	71	13	glutamate	glutamate	NN
cord-310847-63gh2tg4	71	14	transporters	transporter	NNS
cord-310847-63gh2tg4	71	15	work	work	VBP
cord-310847-63gh2tg4	71	16	in	in	IN
cord-310847-63gh2tg4	71	17	reverse	reverse	NN
cord-310847-63gh2tg4	71	18	leading	lead	VBG
cord-310847-63gh2tg4	71	19	to	to	IN
cord-310847-63gh2tg4	71	20	the	the	DT
cord-310847-63gh2tg4	71	21	accumulation	accumulation	NN
cord-310847-63gh2tg4	71	22	of	of	IN
cord-310847-63gh2tg4	71	23	considerations	consideration	NNS
cord-310847-63gh2tg4	71	24	with	with	IN
cord-310847-63gh2tg4	71	25	the	the	DT
cord-310847-63gh2tg4	71	26	recent	recent	JJ
cord-310847-63gh2tg4	71	27	report	report	NN
cord-310847-63gh2tg4	71	28	showing	show	VBG
cord-310847-63gh2tg4	71	29	that	that	IN
cord-310847-63gh2tg4	71	30	IDP	IDP	NNP
cord-310847-63gh2tg4	71	31	affinities	affinity	NNS
cord-310847-63gh2tg4	71	32	are	be	VBP
cord-310847-63gh2tg4	71	33	tuned	tune	VBN
cord-310847-63gh2tg4	71	34	mostly	mostly	RB
cord-310847-63gh2tg4	71	35	by	by	IN
cord-310847-63gh2tg4	71	36	association	association	NN
cord-310847-63gh2tg4	71	37	rates	rate	NNS
cord-310847-63gh2tg4	71	38	45	45	CD
cord-310847-63gh2tg4	72	1	suggests	suggest	VBZ
cord-310847-63gh2tg4	72	2	that	that	IN
cord-310847-63gh2tg4	72	3	the	the	DT
cord-310847-63gh2tg4	72	4	degree	degree	NN
cord-310847-63gh2tg4	72	5	of	of	IN
cord-310847-63gh2tg4	72	6	pre	pre	JJ
cord-310847-63gh2tg4	72	7	-	-	NN
cord-310847-63gh2tg4	72	8	adoption	adoption	NN
cord-310847-63gh2tg4	72	9	of	of	IN
cord-310847-63gh2tg4	72	10	binding	bind	VBG
cord-310847-63gh2tg4	72	11	conformations	conformation	NNS
cord-310847-63gh2tg4	72	12	in	in	IN
cord-310847-63gh2tg4	72	13	IDPs	IDPs	NNP
cord-310847-63gh2tg4	72	14	has	have	VBZ
cord-310847-63gh2tg4	72	15	to	to	TO
cord-310847-63gh2tg4	72	16	be	be	VB
cord-310847-63gh2tg4	72	17	limited	limit	VBN
cord-310847-63gh2tg4	72	18	,	,	,
cord-310847-63gh2tg4	72	19	but	but	CC
cord-310847-63gh2tg4	72	20	not	not	RB
cord-310847-63gh2tg4	72	21	unfavorable	unfavorable	JJ
cord-310847-63gh2tg4	72	22	.	.	.
cord-310847-63gh2tg4	73	1	All	all	PDT
cord-310847-63gh2tg4	73	2	the	the	DT
cord-310847-63gh2tg4	73	3	functional	functional	JJ
cord-310847-63gh2tg4	73	4	and	and	CC
cord-310847-63gh2tg4	73	5	structural	structural	JJ
cord-310847-63gh2tg4	73	6	peculiarities	peculiarity	NNS
cord-310847-63gh2tg4	73	7	of	of	IN
cord-310847-63gh2tg4	73	8	IDPs	IDPs	NNP
cord-310847-63gh2tg4	73	9	/	/	SYM
cord-310847-63gh2tg4	73	10	IDPRs	IDPRs	NNPS
cord-310847-63gh2tg4	73	11	are	be	VBP
cord-310847-63gh2tg4	73	12	encoded	encode	VBN
cord-310847-63gh2tg4	73	13	in	in	IN
cord-310847-63gh2tg4	73	14	their	-PRON-	PRP$
cord-310847-63gh2tg4	73	15	amino	amino	NN
cord-310847-63gh2tg4	73	16	acid	acid	NN
cord-310847-63gh2tg4	73	17	sequences	sequence	NNS
cord-310847-63gh2tg4	73	18	.	.	.
cord-310847-63gh2tg4	74	1	It	-PRON-	PRP
cord-310847-63gh2tg4	74	2	was	be	VBD
cord-310847-63gh2tg4	74	3	recognized	recognize	VBN
cord-310847-63gh2tg4	74	4	long	long	RB
cord-310847-63gh2tg4	74	5	ago	ago	RB
cord-310847-63gh2tg4	74	6	that	that	IN
cord-310847-63gh2tg4	74	7	there	there	EX
cord-310847-63gh2tg4	74	8	are	be	VBP
cord-310847-63gh2tg4	74	9	significant	significant	JJ
cord-310847-63gh2tg4	74	10	differences	difference	NNS
cord-310847-63gh2tg4	74	11	between	between	IN
cord-310847-63gh2tg4	74	12	ordered	order	VBN
cord-310847-63gh2tg4	74	13	proteins	protein	NNS
cord-310847-63gh2tg4	74	14	/	/	SYM
cord-310847-63gh2tg4	74	15	domains	domain	NNS
cord-310847-63gh2tg4	74	16	and	and	CC
cord-310847-63gh2tg4	74	17	IDPs	IDPs	NNP
cord-310847-63gh2tg4	74	18	/	/	SYM
cord-310847-63gh2tg4	74	19	IDPRs	idpr	NNS
cord-310847-63gh2tg4	74	20	at	at	IN
cord-310847-63gh2tg4	74	21	the	the	DT
cord-310847-63gh2tg4	74	22	level	level	NN
cord-310847-63gh2tg4	74	23	of	of	IN
cord-310847-63gh2tg4	74	24	their	-PRON-	PRP$
cord-310847-63gh2tg4	74	25	amino	amino	NN
cord-310847-63gh2tg4	74	26	acid	acid	NN
cord-310847-63gh2tg4	74	27	sequences	sequence	NNS
cord-310847-63gh2tg4	74	28	.	.	.
cord-310847-63gh2tg4	75	1	5	5	CD
cord-310847-63gh2tg4	75	2	,	,	,
cord-310847-63gh2tg4	75	3	10	10	CD
cord-310847-63gh2tg4	75	4	,	,	,
cord-310847-63gh2tg4	75	5	46	46	CD
cord-310847-63gh2tg4	76	1	In	in	IN
cord-310847-63gh2tg4	76	2	fact	fact	NN
cord-310847-63gh2tg4	76	3	,	,	,
cord-310847-63gh2tg4	76	4	in	in	IN
cord-310847-63gh2tg4	76	5	comparison	comparison	NN
cord-310847-63gh2tg4	76	6	with	with	IN
cord-310847-63gh2tg4	76	7	ordered	order	VBN
cord-310847-63gh2tg4	76	8	proteins	protein	NNS
cord-310847-63gh2tg4	76	9	,	,	,
cord-310847-63gh2tg4	76	10	IDPs	IDPs	NNP
cord-310847-63gh2tg4	76	11	/	/	SYM
cord-310847-63gh2tg4	76	12	IDPRs	IDPRs	NNPS
cord-310847-63gh2tg4	76	13	are	be	VBP
cord-310847-63gh2tg4	76	14	characterized	characterize	VBN
cord-310847-63gh2tg4	76	15	by	by	IN
cord-310847-63gh2tg4	76	16	noticeable	noticeable	JJ
cord-310847-63gh2tg4	76	17	biases	bias	NNS
cord-310847-63gh2tg4	76	18	in	in	IN
cord-310847-63gh2tg4	76	19	their	-PRON-	PRP$
cord-310847-63gh2tg4	76	20	amino	amino	NN
cord-310847-63gh2tg4	76	21	acid	acid	NN
cord-310847-63gh2tg4	76	22	compositions	composition	NNS
cord-310847-63gh2tg4	76	23	,	,	,
cord-310847-63gh2tg4	76	24	5	5	CD
cord-310847-63gh2tg4	76	25	,	,	,
cord-310847-63gh2tg4	76	26	8	8	CD
cord-310847-63gh2tg4	76	27	,	,	,
cord-310847-63gh2tg4	76	28	10	10	CD
cord-310847-63gh2tg4	76	29	,	,	,
cord-310847-63gh2tg4	76	30	[	[	-LRB-
cord-310847-63gh2tg4	76	31	46	46	CD
cord-310847-63gh2tg4	76	32	]	]	-RRB-
cord-310847-63gh2tg4	76	33	[	[	-LRB-
cord-310847-63gh2tg4	76	34	47	47	CD
cord-310847-63gh2tg4	76	35	]	]	-RRB-
cord-310847-63gh2tg4	76	36	[	[	-LRB-
cord-310847-63gh2tg4	76	37	48	48	CD
cord-310847-63gh2tg4	76	38	]	]	-RRB-
cord-310847-63gh2tg4	76	39	containing	contain	VBG
cord-310847-63gh2tg4	76	40	less	less	JJR
cord-310847-63gh2tg4	76	41	of	of	IN
cord-310847-63gh2tg4	76	42	so	so	RB
cord-310847-63gh2tg4	76	43	-	-	HYPH
cord-310847-63gh2tg4	76	44	called	call	VBN
cord-310847-63gh2tg4	76	45	"	"	``
cord-310847-63gh2tg4	76	46	order	order	NN
cord-310847-63gh2tg4	76	47	-	-	HYPH
cord-310847-63gh2tg4	76	48	promoting	promote	VBG
cord-310847-63gh2tg4	76	49	"	"	``
cord-310847-63gh2tg4	76	50	residues	residue	NNS
cord-310847-63gh2tg4	76	51	(	(	-LRB-
cord-310847-63gh2tg4	76	52	cysteine	cysteine	NN
cord-310847-63gh2tg4	76	53	,	,	,
cord-310847-63gh2tg4	76	54	tryptophan	tryptophan	NN
cord-310847-63gh2tg4	76	55	,	,	,
cord-310847-63gh2tg4	76	56	isoleucine	isoleucine	NN
cord-310847-63gh2tg4	76	57	,	,	,
cord-310847-63gh2tg4	76	58	tyrosine	tyrosine	NN
cord-310847-63gh2tg4	76	59	,	,	,
cord-310847-63gh2tg4	76	60	phenylalanine	phenylalanine	NN
cord-310847-63gh2tg4	76	61	,	,	,
cord-310847-63gh2tg4	76	62	leucine	leucine	NN
cord-310847-63gh2tg4	76	63	,	,	,
cord-310847-63gh2tg4	76	64	histidine	histidine	NN
cord-310847-63gh2tg4	76	65	,	,	,
cord-310847-63gh2tg4	76	66	valine	valine	NN
cord-310847-63gh2tg4	76	67	,	,	,
cord-310847-63gh2tg4	76	68	asparagines	asparagine	NNS
cord-310847-63gh2tg4	76	69	and	and	CC
cord-310847-63gh2tg4	76	70	methionine	methionine	NN
cord-310847-63gh2tg4	76	71	,	,	,
cord-310847-63gh2tg4	76	72	which	which	WDT
cord-310847-63gh2tg4	76	73	are	be	VBP
cord-310847-63gh2tg4	76	74	mostly	mostly	RB
cord-310847-63gh2tg4	76	75	hydrophobic	hydrophobic	JJ
cord-310847-63gh2tg4	76	76	residues	residue	NNS
cord-310847-63gh2tg4	76	77	which	which	WDT
cord-310847-63gh2tg4	76	78	are	be	VBP
cord-310847-63gh2tg4	76	79	commonly	commonly	RB
cord-310847-63gh2tg4	76	80	found	find	VBN
cord-310847-63gh2tg4	76	81	within	within	IN
cord-310847-63gh2tg4	76	82	the	the	DT
cord-310847-63gh2tg4	76	83	hydrophobic	hydrophobic	JJ
cord-310847-63gh2tg4	76	84	cores	core	NNS
cord-310847-63gh2tg4	76	85	of	of	IN
cord-310847-63gh2tg4	76	86	foldable	foldable	JJ
cord-310847-63gh2tg4	76	87	proteins	protein	NNS
cord-310847-63gh2tg4	76	88	)	)	-RRB-
cord-310847-63gh2tg4	76	89	and	and	CC
cord-310847-63gh2tg4	76	90	more	more	JJR
cord-310847-63gh2tg4	76	91	of	of	IN
cord-310847-63gh2tg4	76	92	"	"	``
cord-310847-63gh2tg4	76	93	disorder	disorder	NN
cord-310847-63gh2tg4	76	94	-	-	HYPH
cord-310847-63gh2tg4	76	95	promoting	promote	VBG
cord-310847-63gh2tg4	76	96	"	"	``
cord-310847-63gh2tg4	76	97	residues	residue	NNS
cord-310847-63gh2tg4	76	98	(	(	-LRB-
cord-310847-63gh2tg4	76	99	lysine	lysine	NN
cord-310847-63gh2tg4	76	100	,	,	,
cord-310847-63gh2tg4	76	101	glutamine	glutamine	NN
cord-310847-63gh2tg4	76	102	,	,	,
cord-310847-63gh2tg4	76	103	serine	serine	NN
cord-310847-63gh2tg4	76	104	,	,	,
cord-310847-63gh2tg4	76	105	glutamic	glutamic	NN
cord-310847-63gh2tg4	76	106	acid	acid	NN
cord-310847-63gh2tg4	76	107	and	and	CC
cord-310847-63gh2tg4	76	108	proline	proline	NN
cord-310847-63gh2tg4	76	109	,	,	,
cord-310847-63gh2tg4	76	110	which	which	WDT
cord-310847-63gh2tg4	76	111	are	be	VBP
cord-310847-63gh2tg4	76	112	mostly	mostly	RB
cord-310847-63gh2tg4	76	113	polar	polar	JJ
cord-310847-63gh2tg4	76	114	and	and	CC
cord-310847-63gh2tg4	76	115	charged	charge	VBN
cord-310847-63gh2tg4	76	116	residues	residue	NNS
cord-310847-63gh2tg4	76	117	,	,	,
cord-310847-63gh2tg4	76	118	which	which	WDT
cord-310847-63gh2tg4	76	119	are	be	VBP
cord-310847-63gh2tg4	76	120	typically	typically	RB
cord-310847-63gh2tg4	76	121	located	locate	VBN
cord-310847-63gh2tg4	76	122	at	at	IN
cord-310847-63gh2tg4	76	123	the	the	DT
cord-310847-63gh2tg4	76	124	surface	surface	NN
cord-310847-63gh2tg4	76	125	of	of	IN
cord-310847-63gh2tg4	76	126	foldable	foldable	JJ
cord-310847-63gh2tg4	76	127	proteins	protein	NNS
cord-310847-63gh2tg4	76	128	)	)	-RRB-
cord-310847-63gh2tg4	76	129	(	(	-LRB-
cord-310847-63gh2tg4	76	130	Fig	Fig	NNP
cord-310847-63gh2tg4	76	131	.	.	.
cord-310847-63gh2tg4	76	132	1A	1a	NN
cord-310847-63gh2tg4	76	133	)	)	-RRB-
cord-310847-63gh2tg4	76	134	.	.	.
cord-310847-63gh2tg4	77	1	Glutamic	glutamic	NN
cord-310847-63gh2tg4	77	2	acid	acid	NN
cord-310847-63gh2tg4	77	3	is	be	VBZ
cord-310847-63gh2tg4	77	4	second	second	JJ
cord-310847-63gh2tg4	77	5	of	of	IN
cord-310847-63gh2tg4	77	6	the	the	DT
cord-310847-63gh2tg4	77	7	most	most	RBS
cord-310847-63gh2tg4	77	8	common	common	JJ
cord-310847-63gh2tg4	77	9	disorder	disorder	NN
cord-310847-63gh2tg4	77	10	-	-	HYPH
cord-310847-63gh2tg4	77	11	promoting	promote	VBG
cord-310847-63gh2tg4	77	12	residues	residue	NNS
cord-310847-63gh2tg4	77	13	.	.	.
cord-310847-63gh2tg4	78	1	Figure	figure	NN
cord-310847-63gh2tg4	78	2	1B	1b	NN
cord-310847-63gh2tg4	78	3	and	and	CC
cord-310847-63gh2tg4	78	4	Table	table	NN
cord-310847-63gh2tg4	78	5	1	1	CD
cord-310847-63gh2tg4	78	6	represent	represent	VBP
cord-310847-63gh2tg4	78	7	the	the	DT
cord-310847-63gh2tg4	78	8	result	result	NN
cord-310847-63gh2tg4	78	9	of	of	IN
cord-310847-63gh2tg4	78	10	a	a	DT
cord-310847-63gh2tg4	78	11	statistical	statistical	JJ
cord-310847-63gh2tg4	78	12	analysis	analysis	NN
cord-310847-63gh2tg4	78	13	of	of	IN
cord-310847-63gh2tg4	78	14	the	the	DT
cord-310847-63gh2tg4	78	15	amino	amino	NN
cord-310847-63gh2tg4	78	16	acid	acid	NN
cord-310847-63gh2tg4	78	17	compositions	composition	NNS
cord-310847-63gh2tg4	78	18	of	of	IN
cord-310847-63gh2tg4	78	19	proteins	protein	NNS
cord-310847-63gh2tg4	78	20	in	in	IN
cord-310847-63gh2tg4	78	21	four	four	CD
cord-310847-63gh2tg4	78	22	standard	standard	JJ
cord-310847-63gh2tg4	78	23	data	data	NN
cord-310847-63gh2tg4	78	24	sets	set	NNS
cord-310847-63gh2tg4	78	25	(	(	-LRB-
cord-310847-63gh2tg4	78	26	DisProt	DisProt	NNS
cord-310847-63gh2tg4	78	27	,	,	,
cord-310847-63gh2tg4	78	28	49	49	CD
cord-310847-63gh2tg4	78	29	UniProt	UniProt	NNP
cord-310847-63gh2tg4	78	30	,	,	,
cord-310847-63gh2tg4	79	1	51	51	CD
cord-310847-63gh2tg4	79	2	PDB	PDB	NNP
cord-310847-63gh2tg4	79	3	Select	Select	NNP
cord-310847-63gh2tg4	79	4	25	25	CD
cord-310847-63gh2tg4	79	5	50	50	CD
cord-310847-63gh2tg4	79	6	and	and	CC
cord-310847-63gh2tg4	79	7	surface	surface	NN
cord-310847-63gh2tg4	79	8	residues	residue	NNS
cord-310847-63gh2tg4	79	9	48	48	CD
cord-310847-63gh2tg4	79	10	)	)	-RRB-
cord-310847-63gh2tg4	79	11	and	and	CC
cord-310847-63gh2tg4	79	12	shows	show	VBZ
cord-310847-63gh2tg4	79	13	that	that	IN
cord-310847-63gh2tg4	79	14	the	the	DT
cord-310847-63gh2tg4	79	15	glutamic	glutamic	NN
cord-310847-63gh2tg4	79	16	acid	acid	NN
cord-310847-63gh2tg4	79	17	content	content	NN
cord-310847-63gh2tg4	79	18	in	in	IN
cord-310847-63gh2tg4	79	19	these	these	DT
cord-310847-63gh2tg4	79	20	data	datum	NNS
cord-310847-63gh2tg4	79	21	sets	set	NNS
cord-310847-63gh2tg4	79	22	is	be	VBZ
cord-310847-63gh2tg4	79	23	9.89	9.89	CD
cord-310847-63gh2tg4	79	24	±	±	CD
cord-310847-63gh2tg4	79	25	0.61	0.61	CD
cord-310847-63gh2tg4	79	26	%	%	NN
cord-310847-63gh2tg4	79	27	,	,	,
cord-310847-63gh2tg4	79	28	6.67	6.67	CD
cord-310847-63gh2tg4	79	29	±	±	CD
cord-310847-63gh2tg4	79	30	0.04	0.04	CD
cord-310847-63gh2tg4	79	31	%	%	NN
cord-310847-63gh2tg4	79	32	,	,	,
cord-310847-63gh2tg4	79	33	6.65	6.65	CD
cord-310847-63gh2tg4	79	34	±	±	CD
cord-310847-63gh2tg4	79	35	0.07	0.07	CD
cord-310847-63gh2tg4	79	36	%	%	NN
cord-310847-63gh2tg4	79	37	and	and	CC
cord-310847-63gh2tg4	79	38	8.70	8.70	CD
cord-310847-63gh2tg4	79	39	±	±	CD
cord-310847-63gh2tg4	79	40	0.17	0.17	CD
cord-310847-63gh2tg4	79	41	%	%	NN
cord-310847-63gh2tg4	79	42	,	,	,
cord-310847-63gh2tg4	79	43	respectively	respectively	RB
cord-310847-63gh2tg4	79	44	(	(	-LRB-
cord-310847-63gh2tg4	79	45	cprofiler.org/help	cprofiler.org/help	UH
cord-310847-63gh2tg4	79	46	.	.	.
cord-310847-63gh2tg4	79	47	html	html	NN
cord-310847-63gh2tg4	79	48	)	)	-RRB-
cord-310847-63gh2tg4	79	49	.	.	.
cord-310847-63gh2tg4	80	1	48	48	CD
cord-310847-63gh2tg4	81	1	In	in	IN
cord-310847-63gh2tg4	81	2	other	other	JJ
cord-310847-63gh2tg4	81	3	words	word	NNS
cord-310847-63gh2tg4	81	4	,	,	,
cord-310847-63gh2tg4	81	5	IDPs	IDPs	NNP
cord-310847-63gh2tg4	81	6	/	/	SYM
cord-310847-63gh2tg4	81	7	IDPRs	IDPRs	NNP
cord-310847-63gh2tg4	81	8	contain	contain	VBP
cord-310847-63gh2tg4	81	9	1.48-and	1.48-and	CD
cord-310847-63gh2tg4	81	10	1.49times	1.49times	CD
cord-310847-63gh2tg4	81	11	more	more	JJR
cord-310847-63gh2tg4	81	12	glutamic	glutamic	NN
cord-310847-63gh2tg4	81	13	acid	acid	NN
cord-310847-63gh2tg4	81	14	residues	residue	NNS
cord-310847-63gh2tg4	81	15	than	than	IN
cord-310847-63gh2tg4	81	16	the	the	DT
cord-310847-63gh2tg4	81	17	average	average	JJ
cord-310847-63gh2tg4	81	18	natural	natural	JJ
cord-310847-63gh2tg4	81	19	proteins	protein	NNS
cord-310847-63gh2tg4	81	20	from	from	IN
cord-310847-63gh2tg4	81	21	UniProt	UniProt	NNP
cord-310847-63gh2tg4	81	22	or	or	CC
cord-310847-63gh2tg4	81	23	ordered	order	VBD
cord-310847-63gh2tg4	81	24	proteins	protein	NNS
cord-310847-63gh2tg4	81	25	from	from	IN
cord-310847-63gh2tg4	81	26	PDB	PDB	NNP
cord-310847-63gh2tg4	81	27	,	,	,
cord-310847-63gh2tg4	81	28	respectively	respectively	RB
cord-310847-63gh2tg4	81	29	.	.	.
cord-310847-63gh2tg4	82	1	Furthermore	furthermore	RB
cord-310847-63gh2tg4	82	2	,	,	,
cord-310847-63gh2tg4	82	3	the	the	DT
cord-310847-63gh2tg4	82	4	glutamic	glutamic	NN
cord-310847-63gh2tg4	82	5	acid	acid	NN
cord-310847-63gh2tg4	82	6	content	content	NN
cord-310847-63gh2tg4	82	7	in	in	IN
cord-310847-63gh2tg4	82	8	IDPs	IDPs	NNP
cord-310847-63gh2tg4	82	9	/	/	SYM
cord-310847-63gh2tg4	82	10	IDPRs	IDPRs	NNP
cord-310847-63gh2tg4	82	11	is	be	VBZ
cord-310847-63gh2tg4	82	12	1.14times	1.14times	CD
cord-310847-63gh2tg4	82	13	higher	high	JJR
cord-310847-63gh2tg4	82	14	than	than	IN
cord-310847-63gh2tg4	82	15	that	that	DT
cord-310847-63gh2tg4	82	16	on	on	IN
cord-310847-63gh2tg4	82	17	the	the	DT
cord-310847-63gh2tg4	82	18	surfaces	surface	NNS
cord-310847-63gh2tg4	82	19	of	of	IN
cord-310847-63gh2tg4	82	20	ordered	order	VBN
cord-310847-63gh2tg4	82	21	proteins	protein	NNS
cord-310847-63gh2tg4	82	22	.	.	.
cord-310847-63gh2tg4	83	1	This	this	DT
cord-310847-63gh2tg4	83	2	article	article	NN
cord-310847-63gh2tg4	83	3	continues	continue	VBZ
cord-310847-63gh2tg4	83	4	a	a	DT
cord-310847-63gh2tg4	83	5	series	series	NN
cord-310847-63gh2tg4	83	6	of	of	IN
cord-310847-63gh2tg4	83	7	publications	publication	NNS
cord-310847-63gh2tg4	83	8	on	on	IN
cord-310847-63gh2tg4	83	9	the	the	DT
cord-310847-63gh2tg4	83	10	intrinsic	intrinsic	JJ
cord-310847-63gh2tg4	83	11	disorder	disorder	NN
cord-310847-63gh2tg4	83	12	alphabet	alphabet	NN
cord-310847-63gh2tg4	83	13	dedicated	dedicate	VBN
cord-310847-63gh2tg4	83	14	to	to	IN
cord-310847-63gh2tg4	83	15	the	the	DT
cord-310847-63gh2tg4	83	16	exploration	exploration	NN
cord-310847-63gh2tg4	83	17	of	of	IN
cord-310847-63gh2tg4	83	18	the	the	DT
cord-310847-63gh2tg4	83	19	amino	amino	NN
cord-310847-63gh2tg4	83	20	acid	acid	NN
cord-310847-63gh2tg4	83	21	determinants	determinant	NNS
cord-310847-63gh2tg4	83	22	of	of	IN
cord-310847-63gh2tg4	83	23	protein	protein	NN
cord-310847-63gh2tg4	83	24	intrinsic	intrinsic	JJ
cord-310847-63gh2tg4	83	25	disorder	disorder	NN
cord-310847-63gh2tg4	83	26	.	.	.
cord-310847-63gh2tg4	84	1	I	-PRON-	PRP
cord-310847-63gh2tg4	84	2	overview	overview	VBP
cord-310847-63gh2tg4	84	3	below	below	IN
cord-310847-63gh2tg4	84	4	some	some	DT
cord-310847-63gh2tg4	84	5	functions	function	NNS
cord-310847-63gh2tg4	84	6	of	of	IN
cord-310847-63gh2tg4	84	7	glutamic	glutamic	NN
cord-310847-63gh2tg4	84	8	acid	acid	NN
cord-310847-63gh2tg4	84	9	in	in	IN
cord-310847-63gh2tg4	84	10	IDPs	IDPs	NNP
cord-310847-63gh2tg4	84	11	/	/	SYM
cord-310847-63gh2tg4	84	12	IDPRs	IDPRs	NNP
cord-310847-63gh2tg4	84	13	(	(	-LRB-
cord-310847-63gh2tg4	84	14	as	as	RB
cord-310847-63gh2tg4	84	15	well	well	RB
cord-310847-63gh2tg4	84	16	as	as	IN
cord-310847-63gh2tg4	84	17	in	in	IN
cord-310847-63gh2tg4	84	18	ordered	order	VBN
cord-310847-63gh2tg4	84	19	proteins	protein	NNS
cord-310847-63gh2tg4	84	20	and	and	CC
cord-310847-63gh2tg4	84	21	domains	domain	NNS
cord-310847-63gh2tg4	84	22	)	)	-RRB-
cord-310847-63gh2tg4	84	23	and	and	CC
cord-310847-63gh2tg4	84	24	show	show	VBP
cord-310847-63gh2tg4	84	25	that	that	IN
cord-310847-63gh2tg4	84	26	there	there	EX
cord-310847-63gh2tg4	84	27	is	be	VBZ
cord-310847-63gh2tg4	84	28	a	a	DT
cord-310847-63gh2tg4	84	29	variety	variety	NN
cord-310847-63gh2tg4	84	30	of	of	IN
cord-310847-63gh2tg4	84	31	glutamic	glutamic	NN
cord-310847-63gh2tg4	84	32	acid	acid	NN
cord-310847-63gh2tg4	84	33	-	-	HYPH
cord-310847-63gh2tg4	84	34	specific	specific	JJ
cord-310847-63gh2tg4	84	35	functions	function	NNS
cord-310847-63gh2tg4	84	36	in	in	IN
cord-310847-63gh2tg4	84	37	disordered	disordered	JJ
cord-310847-63gh2tg4	84	38	proteins	protein	NNS
cord-310847-63gh2tg4	84	39	and	and	CC
cord-310847-63gh2tg4	84	40	regions	region	NNS
cord-310847-63gh2tg4	84	41	.	.	.
cord-310847-63gh2tg4	85	1	Chemical	chemical	JJ
cord-310847-63gh2tg4	85	2	structure	structure	NN
cord-310847-63gh2tg4	85	3	of	of	IN
cord-310847-63gh2tg4	85	4	glutamic	glutamic	NN
cord-310847-63gh2tg4	85	5	acid	acid	NN
cord-310847-63gh2tg4	85	6	.	.	.
cord-310847-63gh2tg4	86	1	Glutamic	glutamic	NN
cord-310847-63gh2tg4	86	2	acid	acid	NN
cord-310847-63gh2tg4	86	3	(	(	-LRB-
cord-310847-63gh2tg4	86	4	glutamate	glutamate	NN
cord-310847-63gh2tg4	86	5	,	,	,
cord-310847-63gh2tg4	86	6	Glu	Glu	NNP
cord-310847-63gh2tg4	86	7	,	,	,
cord-310847-63gh2tg4	86	8	E	E	NNP
cord-310847-63gh2tg4	86	9	,	,	,
cord-310847-63gh2tg4	86	10	see	see	VB
cord-310847-63gh2tg4	86	11	Fig	Fig	NNP
cord-310847-63gh2tg4	86	12	.	.	.
cord-310847-63gh2tg4	86	13	2A	2a	CD
cord-310847-63gh2tg4	86	14	)	)	-RRB-
cord-310847-63gh2tg4	86	15	is	be	VBZ
cord-310847-63gh2tg4	86	16	one	one	CD
cord-310847-63gh2tg4	86	17	of	of	IN
cord-310847-63gh2tg4	86	18	the	the	DT
cord-310847-63gh2tg4	86	19	20	20	CD
cord-310847-63gh2tg4	86	20	proteinogenic	proteinogenic	JJ
cord-310847-63gh2tg4	86	21	amino	amino	NN
cord-310847-63gh2tg4	86	22	acids	acid	NNS
cord-310847-63gh2tg4	86	23	encoded	encode	VBN
cord-310847-63gh2tg4	86	24	by	by	IN
cord-310847-63gh2tg4	86	25	the	the	DT
cord-310847-63gh2tg4	86	26	standard	standard	JJ
cord-310847-63gh2tg4	86	27	genetic	genetic	JJ
cord-310847-63gh2tg4	86	28	code	code	NN
cord-310847-63gh2tg4	86	29	and	and	CC
cord-310847-63gh2tg4	86	30	its	-PRON-	PRP$
cord-310847-63gh2tg4	86	31	codons	codon	NNS
cord-310847-63gh2tg4	86	32	are	be	VBP
cord-310847-63gh2tg4	86	33	GAA	GAA	NNP
cord-310847-63gh2tg4	86	34	and	and	CC
cord-310847-63gh2tg4	86	35	GAG	gag	NN
cord-310847-63gh2tg4	86	36	.	.	.
cord-310847-63gh2tg4	87	1	Glutamic	glutamic	NN
cord-310847-63gh2tg4	87	2	acid	acid	NN
cord-310847-63gh2tg4	87	3	is	be	VBZ
cord-310847-63gh2tg4	87	4	a	a	DT
cord-310847-63gh2tg4	87	5	dibasic	dibasic	NN
cord-310847-63gh2tg4	87	6	nonessential	nonessential	JJ
cord-310847-63gh2tg4	87	7	amino	amino	NN
cord-310847-63gh2tg4	87	8	acid	acid	NN
cord-310847-63gh2tg4	87	9	that	that	WDT
cord-310847-63gh2tg4	87	10	has	have	VBZ
cord-310847-63gh2tg4	87	11	a	a	DT
cord-310847-63gh2tg4	87	12	molecular	molecular	JJ
cord-310847-63gh2tg4	87	13	mass	mass	NN
cord-310847-63gh2tg4	87	14	of	of	IN
cord-310847-63gh2tg4	87	15	147.13	147.13	CD
cord-310847-63gh2tg4	87	16	Da	Da	NNP
cord-310847-63gh2tg4	87	17	(	(	-LRB-
cord-310847-63gh2tg4	87	18	molecular	molecular	JJ
cord-310847-63gh2tg4	87	19	mass	mass	NN
cord-310847-63gh2tg4	87	20	of	of	IN
cord-310847-63gh2tg4	87	21	Glu	Glu	NNP
cord-310847-63gh2tg4	87	22	residue	residue	NN
cord-310847-63gh2tg4	87	23	is	be	VBZ
cord-310847-63gh2tg4	87	24	129.12	129.12	CD
cord-310847-63gh2tg4	87	25	Da	Da	NNP
cord-310847-63gh2tg4	87	26	)	)	-RRB-
cord-310847-63gh2tg4	87	27	,	,	,
cord-310847-63gh2tg4	87	28	surface	surface	NN
cord-310847-63gh2tg4	87	29	of	of	IN
cord-310847-63gh2tg4	87	30	190	190	CD
cord-310847-63gh2tg4	87	31	Å	å	NN
cord-310847-63gh2tg4	87	32	2	2	CD
cord-310847-63gh2tg4	87	33	,	,	,
cord-310847-63gh2tg4	87	34	volume	volume	NN
cord-310847-63gh2tg4	87	35	of	of	IN
cord-310847-63gh2tg4	87	36	138.4	138.4	CD
cord-310847-63gh2tg4	87	37	Å	å	NN
cord-310847-63gh2tg4	87	38	3	3	CD
cord-310847-63gh2tg4	87	39	,	,	,
cord-310847-63gh2tg4	87	40	pK	pK	NNP
cord-310847-63gh2tg4	87	41	a	a	DT
cord-310847-63gh2tg4	87	42	of	of	IN
cord-310847-63gh2tg4	87	43	side	side	NN
cord-310847-63gh2tg4	87	44	chain	chain	NN
cord-310847-63gh2tg4	87	45	of	of	IN
cord-310847-63gh2tg4	87	46	4.6	4.6	CD
cord-310847-63gh2tg4	87	47	and	and	CC
cord-310847-63gh2tg4	87	48	pI	pI	NNP
cord-310847-63gh2tg4	87	49	3.08	3.08	CD
cord-310847-63gh2tg4	87	50	at	at	IN
cord-310847-63gh2tg4	87	51	25	25	CD
cord-310847-63gh2tg4	87	52	°	°	NN
cord-310847-63gh2tg4	87	53	C	c	NN
cord-310847-63gh2tg4	87	54	.	.	.
cord-310847-63gh2tg4	88	1	Intriguingly	intriguingly	RB
cord-310847-63gh2tg4	88	2	,	,	,
cord-310847-63gh2tg4	88	3	free	free	JJ
cord-310847-63gh2tg4	88	4	glutamic	glutamic	NN
cord-310847-63gh2tg4	88	5	acid	acid	NN
cord-310847-63gh2tg4	88	6	is	be	VBZ
cord-310847-63gh2tg4	88	7	not	not	RB
cord-310847-63gh2tg4	88	8	very	very	RB
cord-310847-63gh2tg4	88	9	soluble	soluble	JJ
cord-310847-63gh2tg4	88	10	,	,	,
cord-310847-63gh2tg4	88	11	possessing	possess	VBG
cord-310847-63gh2tg4	88	12	solubility	solubility	NN
cord-310847-63gh2tg4	88	13	of	of	IN
cord-310847-63gh2tg4	88	14	0.864	0.864	CD
cord-310847-63gh2tg4	88	15	g/100	g/100	NNS
cord-310847-63gh2tg4	89	1	g	g	NN
cord-310847-63gh2tg4	89	2	at	at	IN
cord-310847-63gh2tg4	89	3	25	25	CD
cord-310847-63gh2tg4	89	4	°	°	NN
cord-310847-63gh2tg4	89	5	C	c	NN
cord-310847-63gh2tg4	89	6	,	,	,
cord-310847-63gh2tg4	89	7	which	which	WDT
cord-310847-63gh2tg4	89	8	is	be	VBZ
cord-310847-63gh2tg4	89	9	significantly	significantly	RB
cord-310847-63gh2tg4	89	10	lower	low	JJR
cord-310847-63gh2tg4	89	11	than	than	IN
cord-310847-63gh2tg4	89	12	the	the	DT
cord-310847-63gh2tg4	89	13	solubility	solubility	NN
cord-310847-63gh2tg4	89	14	of	of	IN
cord-310847-63gh2tg4	89	15	free	free	JJ
cord-310847-63gh2tg4	89	16	prolines	proline	NNS
cord-310847-63gh2tg4	89	17	(	(	-LRB-
cord-310847-63gh2tg4	89	18	162.3	162.3	CD
cord-310847-63gh2tg4	89	19	g/100	g/100	NN
cord-310847-63gh2tg4	89	20	g	g	NN
cord-310847-63gh2tg4	89	21	at	at	IN
cord-310847-63gh2tg4	89	22	25	25	CD
cord-310847-63gh2tg4	89	23	°	°	NN
cord-310847-63gh2tg4	89	24	C	C	NNP
cord-310847-63gh2tg4	89	25	)	)	-RRB-
cord-310847-63gh2tg4	89	26	,	,	,
cord-310847-63gh2tg4	89	27	and	and	CC
cord-310847-63gh2tg4	89	28	the	the	DT
cord-310847-63gh2tg4	89	29	solubility	solubility	NN
cord-310847-63gh2tg4	89	30	of	of	IN
cord-310847-63gh2tg4	89	31	the	the	DT
cord-310847-63gh2tg4	89	32	vast	vast	JJ
cord-310847-63gh2tg4	89	33	majority	majority	NN
cord-310847-63gh2tg4	89	34	of	of	IN
cord-310847-63gh2tg4	89	35	free	free	JJ
cord-310847-63gh2tg4	89	36	amino	amino	NN
cord-310847-63gh2tg4	89	37	acids	acid	NNS
cord-310847-63gh2tg4	89	38	(	(	-LRB-
cord-310847-63gh2tg4	89	39	www.fli-leibniz.de/	www.fli-leibniz.de/	NNP
cord-310847-63gh2tg4	89	40	IMAGE_AA.html	image_aa.html	NN
cord-310847-63gh2tg4	89	41	)	)	-RRB-
cord-310847-63gh2tg4	89	42	.	.	.
cord-310847-63gh2tg4	90	1	The	the	DT
cord-310847-63gh2tg4	90	2	side	side	NN
cord-310847-63gh2tg4	90	3	chain	chain	NN
cord-310847-63gh2tg4	90	4	of	of	IN
cord-310847-63gh2tg4	90	5	glutamic	glutamic	NN
cord-310847-63gh2tg4	90	6	acid	acid	NN
cord-310847-63gh2tg4	90	7	contains	contain	VBZ
cord-310847-63gh2tg4	90	8	two	two	CD
cord-310847-63gh2tg4	90	9	methylene	methylene	NN
cord-310847-63gh2tg4	90	10	group	group	NN
cord-310847-63gh2tg4	90	11	and	and	CC
cord-310847-63gh2tg4	90	12	the	the	DT
cord-310847-63gh2tg4	90	13	carboxylic	carboxylic	JJ
cord-310847-63gh2tg4	90	14	acid	acid	NN
cord-310847-63gh2tg4	90	15	functional	functional	JJ
cord-310847-63gh2tg4	90	16	group	group	NN
cord-310847-63gh2tg4	90	17	(	(	-LRB-
cord-310847-63gh2tg4	90	18	see	see	VB
cord-310847-63gh2tg4	90	19	Fig	Fig	NNP
cord-310847-63gh2tg4	90	20	.	.	.
cord-310847-63gh2tg4	90	21	2A	2a	LS
cord-310847-63gh2tg4	90	22	)	)	-RRB-
cord-310847-63gh2tg4	90	23	that	that	WDT
cord-310847-63gh2tg4	90	24	exists	exist	VBZ
cord-310847-63gh2tg4	90	25	in	in	IN
cord-310847-63gh2tg4	90	26	a	a	DT
cord-310847-63gh2tg4	90	27	negatively	negatively	RB
cord-310847-63gh2tg4	90	28	charged	charge	VBN
cord-310847-63gh2tg4	90	29	deprotonated	deprotonated	JJ
cord-310847-63gh2tg4	90	30	carboxylate	carboxylate	NNP
cord-310847-63gh2tg4	90	31	with	with	IN
cord-310847-63gh2tg4	90	32	stroke	stroke	NN
cord-310847-63gh2tg4	90	33	,	,	,
cord-310847-63gh2tg4	90	34	autism	autism	NN
cord-310847-63gh2tg4	90	35	,	,	,
cord-310847-63gh2tg4	90	36	amyotrophic	amyotrophic	JJ
cord-310847-63gh2tg4	90	37	lateral	lateral	JJ
cord-310847-63gh2tg4	90	38	sclerosis	sclerosis	NN
cord-310847-63gh2tg4	90	39	,	,	,
cord-310847-63gh2tg4	90	40	lathyrism	lathyrism	NNP
cord-310847-63gh2tg4	90	41	,	,	,
cord-310847-63gh2tg4	90	42	some	some	DT
cord-310847-63gh2tg4	90	43	forms	form	NNS
cord-310847-63gh2tg4	90	44	of	of	IN
cord-310847-63gh2tg4	90	45	mental	mental	JJ
cord-310847-63gh2tg4	90	46	retardation	retardation	NN
cord-310847-63gh2tg4	90	47	and	and	CC
cord-310847-63gh2tg4	90	48	Alzheimer	Alzheimer	NNP
cord-310847-63gh2tg4	90	49	's	's	POS
cord-310847-63gh2tg4	90	50	disease	disease	NN
cord-310847-63gh2tg4	90	51	.	.	.
cord-310847-63gh2tg4	91	1	58	58	CD
cord-310847-63gh2tg4	92	1	The	the	DT
cord-310847-63gh2tg4	92	2	decreased	decrease	VBN
cord-310847-63gh2tg4	92	3	glutamate	glutamate	NN
cord-310847-63gh2tg4	92	4	release	release	NN
cord-310847-63gh2tg4	92	5	is	be	VBZ
cord-310847-63gh2tg4	92	6	associated	associate	VBN
cord-310847-63gh2tg4	92	7	with	with	IN
cord-310847-63gh2tg4	92	8	phenylketonuria	phenylketonuria	NN
cord-310847-63gh2tg4	92	9	leading	lead	VBG
cord-310847-63gh2tg4	92	10	to	to	IN
cord-310847-63gh2tg4	92	11	the	the	DT
cord-310847-63gh2tg4	92	12	developmental	developmental	JJ
cord-310847-63gh2tg4	92	13	disruption	disruption	NN
cord-310847-63gh2tg4	92	14	of	of	IN
cord-310847-63gh2tg4	92	15	glutamate	glutamate	NN
cord-310847-63gh2tg4	92	16	receptor	receptor	NN
cord-310847-63gh2tg4	92	17	expression	expression	NN
cord-310847-63gh2tg4	92	18	.	.	.
cord-310847-63gh2tg4	93	1	59	59	CD
cord-310847-63gh2tg4	93	2	,	,	,
cord-310847-63gh2tg4	93	3	60	60	CD
cord-310847-63gh2tg4	93	4	the	the	DT
cord-310847-63gh2tg4	93	5	excess	excess	JJ
cord-310847-63gh2tg4	93	6	glutamate	glutamate	NN
cord-310847-63gh2tg4	93	7	in	in	IN
cord-310847-63gh2tg4	93	8	the	the	DT
cord-310847-63gh2tg4	93	9	extracellular	extracellular	JJ
cord-310847-63gh2tg4	93	10	space	space	NN
cord-310847-63gh2tg4	93	11	and	and	CC
cord-310847-63gh2tg4	93	12	promoting	promote	VBG
cord-310847-63gh2tg4	93	13	entrance	entrance	NN
cord-310847-63gh2tg4	93	14	of	of	IN
cord-310847-63gh2tg4	93	15	calcium	calcium	NN
cord-310847-63gh2tg4	93	16	to	to	IN
cord-310847-63gh2tg4	93	17	the	the	DT
cord-310847-63gh2tg4	93	18	cell	cell	NN
cord-310847-63gh2tg4	93	19	via	via	IN
cord-310847-63gh2tg4	93	20	the	the	DT
cord-310847-63gh2tg4	93	21	NMDA	NMDA	NNP
cord-310847-63gh2tg4	93	22	receptor	receptor	NN
cord-310847-63gh2tg4	93	23	channels	channel	NNS
cord-310847-63gh2tg4	93	24	.	.	.
cord-310847-63gh2tg4	94	1	This	this	DT
cord-310847-63gh2tg4	94	2	process	process	NN
cord-310847-63gh2tg4	94	3	is	be	VBZ
cord-310847-63gh2tg4	94	4	known	know	VBN
cord-310847-63gh2tg4	94	5	as	as	IN
cord-310847-63gh2tg4	94	6	excitotoxicity	excitotoxicity	NN
cord-310847-63gh2tg4	94	7	,	,	,
cord-310847-63gh2tg4	94	8	and	and	CC
cord-310847-63gh2tg4	94	9	it	-PRON-	PRP
cord-310847-63gh2tg4	94	10	results	result	VBZ
cord-310847-63gh2tg4	94	11	in	in	IN
cord-310847-63gh2tg4	94	12	neuronal	neuronal	JJ
cord-310847-63gh2tg4	94	13	damage	damage	NN
cord-310847-63gh2tg4	94	14	and	and	CC
cord-310847-63gh2tg4	94	15	eventual	eventual	JJ
cord-310847-63gh2tg4	94	16	cell	cell	NN
cord-310847-63gh2tg4	94	17	death	death	NN
cord-310847-63gh2tg4	94	18	.	.	.
cord-310847-63gh2tg4	95	1	The	the	DT
cord-310847-63gh2tg4	95	2	excitotoxicity	excitotoxicity	NN
cord-310847-63gh2tg4	95	3	might	may	MD
cord-310847-63gh2tg4	95	4	occur	occur	VB
cord-310847-63gh2tg4	95	5	as	as	IN
cord-310847-63gh2tg4	95	6	part	part	NN
cord-310847-63gh2tg4	95	7	of	of	IN
cord-310847-63gh2tg4	95	8	the	the	DT
cord-310847-63gh2tg4	95	9	ischemic	ischemic	JJ
cord-310847-63gh2tg4	95	10	cascade	cascade	NN
cord-310847-63gh2tg4	95	11	that	that	WDT
cord-310847-63gh2tg4	95	12	is	be	VBZ
cord-310847-63gh2tg4	95	13	associated	associate	VBN
cord-310847-63gh2tg4	95	14	Figure	Figure	NNP
cord-310847-63gh2tg4	95	15	1	1	CD
cord-310847-63gh2tg4	95	16	.	.	.
cord-310847-63gh2tg4	96	1	amino	amino	NN
cord-310847-63gh2tg4	96	2	acid	acid	NN
cord-310847-63gh2tg4	96	3	determinants	determinant	NNS
cord-310847-63gh2tg4	96	4	defining	define	VBG
cord-310847-63gh2tg4	96	5	structural	structural	JJ
cord-310847-63gh2tg4	96	6	and	and	CC
cord-310847-63gh2tg4	96	7	functional	functional	JJ
cord-310847-63gh2tg4	96	8	differences	difference	NNS
cord-310847-63gh2tg4	96	9	between	between	IN
cord-310847-63gh2tg4	96	10	the	the	DT
cord-310847-63gh2tg4	96	11	ordered	order	VBN
cord-310847-63gh2tg4	96	12	and	and	CC
cord-310847-63gh2tg4	96	13	intrinsically	intrinsically	RB
cord-310847-63gh2tg4	96	14	disordered	disordered	JJ
cord-310847-63gh2tg4	96	15	proteins	protein	NNS
cord-310847-63gh2tg4	96	16	.	.	.
cord-310847-63gh2tg4	97	1	(	(	-LRB-
cord-310847-63gh2tg4	97	2	A	a	DT
cord-310847-63gh2tg4	97	3	)	)	-RRB-
cord-310847-63gh2tg4	97	4	Fractional	fractional	JJ
cord-310847-63gh2tg4	97	5	difference	difference	NN
cord-310847-63gh2tg4	97	6	in	in	IN
cord-310847-63gh2tg4	97	7	the	the	DT
cord-310847-63gh2tg4	97	8	amino	amino	NN
cord-310847-63gh2tg4	97	9	acid	acid	NN
cord-310847-63gh2tg4	97	10	composition	composition	NN
cord-310847-63gh2tg4	97	11	(	(	-LRB-
cord-310847-63gh2tg4	97	12	compositional	compositional	JJ
cord-310847-63gh2tg4	97	13	profile	profile	NN
cord-310847-63gh2tg4	97	14	)	)	-RRB-
cord-310847-63gh2tg4	97	15	between	between	IN
cord-310847-63gh2tg4	97	16	the	the	DT
cord-310847-63gh2tg4	97	17	typical	typical	JJ
cord-310847-63gh2tg4	97	18	IDPs	IDPs	NNP
cord-310847-63gh2tg4	97	19	from	from	IN
cord-310847-63gh2tg4	97	20	the	the	DT
cord-310847-63gh2tg4	97	21	DisProt	DisProt	NNPS
cord-310847-63gh2tg4	97	22	database	database	NN
cord-310847-63gh2tg4	97	23	49	49	CD
cord-310847-63gh2tg4	97	24	and	and	CC
cord-310847-63gh2tg4	97	25	a	a	DT
cord-310847-63gh2tg4	97	26	set	set	NN
cord-310847-63gh2tg4	97	27	of	of	IN
cord-310847-63gh2tg4	97	28	completely	completely	RB
cord-310847-63gh2tg4	97	29	ordered	order	VBN
cord-310847-63gh2tg4	97	30	proteins	protein	NNS
cord-310847-63gh2tg4	97	31	50	50	CD
cord-310847-63gh2tg4	97	32	calculated	calculate	VBN
cord-310847-63gh2tg4	97	33	for	for	IN
cord-310847-63gh2tg4	97	34	each	each	DT
cord-310847-63gh2tg4	97	35	amino	amino	NN
cord-310847-63gh2tg4	97	36	acid	acid	NN
cord-310847-63gh2tg4	97	37	residue	residue	NN
cord-310847-63gh2tg4	97	38	.	.	.
cord-310847-63gh2tg4	98	1	The	the	DT
cord-310847-63gh2tg4	98	2	fractional	fractional	JJ
cord-310847-63gh2tg4	98	3	difference	difference	NN
cord-310847-63gh2tg4	98	4	was	be	VBD
cord-310847-63gh2tg4	98	5	evaluated	evaluate	VBN
cord-310847-63gh2tg4	98	6	as	as	IN
cord-310847-63gh2tg4	98	7	(	(	-LRB-
cord-310847-63gh2tg4	98	8	C	C	NNP
cord-310847-63gh2tg4	98	9	DisProt	DisProt	NNS
cord-310847-63gh2tg4	98	10	−	−	NN
cord-310847-63gh2tg4	98	11	C	c	NN
cord-310847-63gh2tg4	98	12	PDB	pdb	NN
cord-310847-63gh2tg4	98	13	)	)	-RRB-
cord-310847-63gh2tg4	99	1	/C	/C	NNP
cord-310847-63gh2tg4	99	2	PDB	PDB	NNP
cord-310847-63gh2tg4	99	3	,	,	,
cord-310847-63gh2tg4	99	4	where	where	WRB
cord-310847-63gh2tg4	99	5	C	C	NNP
cord-310847-63gh2tg4	99	6	DisProt	DisProt	NNPS
cord-310847-63gh2tg4	99	7	is	be	VBZ
cord-310847-63gh2tg4	99	8	the	the	DT
cord-310847-63gh2tg4	99	9	content	content	NN
cord-310847-63gh2tg4	99	10	of	of	IN
cord-310847-63gh2tg4	99	11	a	a	DT
cord-310847-63gh2tg4	99	12	given	give	VBN
cord-310847-63gh2tg4	99	13	amino	amino	NN
cord-310847-63gh2tg4	99	14	acid	acid	NN
cord-310847-63gh2tg4	99	15	in	in	IN
cord-310847-63gh2tg4	99	16	a	a	DT
cord-310847-63gh2tg4	99	17	DisProt	DisProt	NNP
cord-310847-63gh2tg4	99	18	databse	databse	NN
cord-310847-63gh2tg4	99	19	,	,	,
cord-310847-63gh2tg4	99	20	and	and	CC
cord-310847-63gh2tg4	99	21	C	C	NNP
cord-310847-63gh2tg4	99	22	PDB	PDB	NNP
cord-310847-63gh2tg4	99	23	is	be	VBZ
cord-310847-63gh2tg4	99	24	the	the	DT
cord-310847-63gh2tg4	99	25	corresponding	corresponding	JJ
cord-310847-63gh2tg4	99	26	content	content	NN
cord-310847-63gh2tg4	99	27	in	in	IN
cord-310847-63gh2tg4	99	28	the	the	DT
cord-310847-63gh2tg4	99	29	data	datum	NNS
cord-310847-63gh2tg4	99	30	set	set	VBN
cord-310847-63gh2tg4	99	31	of	of	IN
cord-310847-63gh2tg4	99	32	fully	fully	RB
cord-310847-63gh2tg4	99	33	ordered	order	VBN
cord-310847-63gh2tg4	99	34	proteins	protein	NNS
cord-310847-63gh2tg4	99	35	.	.	.
cord-310847-63gh2tg4	100	1	Positive	positive	JJ
cord-310847-63gh2tg4	100	2	bars	bar	NNS
cord-310847-63gh2tg4	100	3	correspond	correspond	VBP
cord-310847-63gh2tg4	100	4	to	to	IN
cord-310847-63gh2tg4	100	5	residues	residue	NNS
cord-310847-63gh2tg4	100	6	found	find	VBD
cord-310847-63gh2tg4	100	7	more	more	RBR
cord-310847-63gh2tg4	100	8	abundantly	abundantly	RB
cord-310847-63gh2tg4	100	9	in	in	IN
cord-310847-63gh2tg4	100	10	IDPs	idp	NNS
cord-310847-63gh2tg4	100	11	,	,	,
cord-310847-63gh2tg4	100	12	whereas	whereas	IN
cord-310847-63gh2tg4	100	13	negative	negative	JJ
cord-310847-63gh2tg4	100	14	bars	bar	NNS
cord-310847-63gh2tg4	100	15	show	show	VBP
cord-310847-63gh2tg4	100	16	residues	residue	NNS
cord-310847-63gh2tg4	100	17	,	,	,
cord-310847-63gh2tg4	100	18	in	in	IN
cord-310847-63gh2tg4	100	19	which	which	WDT
cord-310847-63gh2tg4	100	20	IDPs	idp	NNS
cord-310847-63gh2tg4	100	21	are	be	VBP
cord-310847-63gh2tg4	100	22	depleted	deplete	VBN
cord-310847-63gh2tg4	100	23	.	.	.
cord-310847-63gh2tg4	101	1	amino	amino	NN
cord-310847-63gh2tg4	101	2	acid	acid	NN
cord-310847-63gh2tg4	101	3	types	type	NNS
cord-310847-63gh2tg4	101	4	were	be	VBD
cord-310847-63gh2tg4	101	5	ranked	rank	VBN
cord-310847-63gh2tg4	101	6	according	accord	VBG
cord-310847-63gh2tg4	101	7	to	to	IN
cord-310847-63gh2tg4	101	8	their	-PRON-	PRP$
cord-310847-63gh2tg4	101	9	decreasing	decrease	VBG
cord-310847-63gh2tg4	101	10	disorder	disorder	NN
cord-310847-63gh2tg4	101	11	-	-	HYPH
cord-310847-63gh2tg4	101	12	promoting	promote	VBG
cord-310847-63gh2tg4	101	13	potential	potential	NN
cord-310847-63gh2tg4	101	14	.	.	.
cord-310847-63gh2tg4	102	1	47	47	CD
cord-310847-63gh2tg4	103	1	(	(	-LRB-
cord-310847-63gh2tg4	103	2	B	b	NN
cord-310847-63gh2tg4	103	3	)	)	-RRB-
cord-310847-63gh2tg4	103	4	amino	amino	NN
cord-310847-63gh2tg4	103	5	acid	acid	NN
cord-310847-63gh2tg4	103	6	compositions	composition	NNS
cord-310847-63gh2tg4	103	7	of	of	IN
cord-310847-63gh2tg4	103	8	several	several	JJ
cord-310847-63gh2tg4	103	9	data	data	NN
cord-310847-63gh2tg4	103	10	sets	set	NNS
cord-310847-63gh2tg4	103	11	discussed	discuss	VBN
cord-310847-63gh2tg4	103	12	in	in	IN
cord-310847-63gh2tg4	103	13	the	the	DT
cord-310847-63gh2tg4	103	14	text	text	NN
cord-310847-63gh2tg4	103	15	(	(	-LRB-
cord-310847-63gh2tg4	103	16	DisProt	disprot	UH
cord-310847-63gh2tg4	103	17	,	,	,
cord-310847-63gh2tg4	103	18	49	49	CD
cord-310847-63gh2tg4	103	19	UniProt	UniProt	NNP
cord-310847-63gh2tg4	103	20	,	,	,
cord-310847-63gh2tg4	104	1	51	51	CD
cord-310847-63gh2tg4	104	2	PDB	PDB	NNP
cord-310847-63gh2tg4	104	3	Select	Select	NNP
cord-310847-63gh2tg4	104	4	25	25	CD
cord-310847-63gh2tg4	104	5	50	50	CD
cord-310847-63gh2tg4	104	6	and	and	CC
cord-310847-63gh2tg4	104	7	surface	surface	NN
cord-310847-63gh2tg4	104	8	residues	residue	NNS
cord-310847-63gh2tg4	104	9	48	48	CD
cord-310847-63gh2tg4	104	10	)	)	-RRB-
cord-310847-63gh2tg4	104	11	.	.	.
cord-310847-63gh2tg4	105	1	linkages	linkage	NNS
cord-310847-63gh2tg4	105	2	,	,	,
cord-310847-63gh2tg4	105	3	or	or	CC
cord-310847-63gh2tg4	105	4	ion	ion	NN
cord-310847-63gh2tg4	105	5	pairs	pair	NNS
cord-310847-63gh2tg4	105	6	.	.	.
cord-310847-63gh2tg4	106	1	An	an	DT
cord-310847-63gh2tg4	106	2	electrostatic	electrostatic	JJ
cord-310847-63gh2tg4	106	3	interaction	interaction	NN
cord-310847-63gh2tg4	106	4	is	be	VBZ
cord-310847-63gh2tg4	106	5	a	a	DT
cord-310847-63gh2tg4	106	6	non	non	JJ
cord-310847-63gh2tg4	106	7	-	-	JJ
cord-310847-63gh2tg4	106	8	covalent	covalent	JJ
cord-310847-63gh2tg4	106	9	bond	bond	NN
cord-310847-63gh2tg4	106	10	that	that	WDT
cord-310847-63gh2tg4	106	11	is	be	VBZ
cord-310847-63gh2tg4	106	12	based	base	VBN
cord-310847-63gh2tg4	106	13	on	on	IN
cord-310847-63gh2tg4	106	14	the	the	DT
cord-310847-63gh2tg4	106	15	attraction	attraction	NN
cord-310847-63gh2tg4	106	16	of	of	IN
cord-310847-63gh2tg4	106	17	two	two	CD
cord-310847-63gh2tg4	106	18	oppositely	oppositely	RB
cord-310847-63gh2tg4	106	19	charged	charge	VBN
cord-310847-63gh2tg4	106	20	groups	group	NNS
cord-310847-63gh2tg4	106	21	.	.	.
cord-310847-63gh2tg4	107	1	It	-PRON-	PRP
cord-310847-63gh2tg4	107	2	can	can	MD
cord-310847-63gh2tg4	107	3	easily	easily	RB
cord-310847-63gh2tg4	107	4	be	be	VB
cord-310847-63gh2tg4	107	5	broken	break	VBN
cord-310847-63gh2tg4	107	6	and	and	CC
cord-310847-63gh2tg4	107	7	reformed	reform	VBN
cord-310847-63gh2tg4	107	8	and	and	CC
cord-310847-63gh2tg4	107	9	is	be	VBZ
cord-310847-63gh2tg4	107	10	characterized	characterize	VBN
cord-310847-63gh2tg4	107	11	by	by	IN
cord-310847-63gh2tg4	107	12	the	the	DT
cord-310847-63gh2tg4	107	13	optimal	optimal	JJ
cord-310847-63gh2tg4	107	14	distance	distance	NN
cord-310847-63gh2tg4	107	15	of	of	IN
cord-310847-63gh2tg4	107	16	2.8	2.8	CD
cord-310847-63gh2tg4	107	17	Å	å	NN
cord-310847-63gh2tg4	107	18	between	between	IN
cord-310847-63gh2tg4	107	19	the	the	DT
cord-310847-63gh2tg4	107	20	interacting	interact	VBG
cord-310847-63gh2tg4	107	21	groups	group	NNS
cord-310847-63gh2tg4	107	22	.	.	.
cord-310847-63gh2tg4	108	1	The	the	DT
cord-310847-63gh2tg4	108	2	strength	strength	NN
cord-310847-63gh2tg4	108	3	of	of	IN
cord-310847-63gh2tg4	108	4	these	these	DT
cord-310847-63gh2tg4	108	5	interactions	interaction	NNS
cord-310847-63gh2tg4	108	6	depends	depend	VBZ
cord-310847-63gh2tg4	108	7	on	on	IN
cord-310847-63gh2tg4	108	8	the	the	DT
cord-310847-63gh2tg4	108	9	distance	distance	NN
cord-310847-63gh2tg4	108	10	of	of	IN
cord-310847-63gh2tg4	108	11	the	the	DT
cord-310847-63gh2tg4	108	12	two	two	CD
cord-310847-63gh2tg4	108	13	charges	charge	NNS
cord-310847-63gh2tg4	108	14	and	and	CC
cord-310847-63gh2tg4	108	15	the	the	DT
cord-310847-63gh2tg4	108	16	properties	property	NNS
cord-310847-63gh2tg4	108	17	of	of	IN
cord-310847-63gh2tg4	108	18	the	the	DT
cord-310847-63gh2tg4	108	19	medium	medium	NN
cord-310847-63gh2tg4	108	20	between	between	IN
cord-310847-63gh2tg4	108	21	them	-PRON-	PRP
cord-310847-63gh2tg4	108	22	.	.	.
cord-310847-63gh2tg4	109	1	In	in	IN
cord-310847-63gh2tg4	109	2	proteins	protein	NNS
cord-310847-63gh2tg4	109	3	,	,	,
cord-310847-63gh2tg4	109	4	electrostatic	electrostatic	JJ
cord-310847-63gh2tg4	109	5	interactions	interaction	NNS
cord-310847-63gh2tg4	109	6	typically	typically	RB
cord-310847-63gh2tg4	109	7	occur	occur	VBP
cord-310847-63gh2tg4	109	8	between	between	IN
cord-310847-63gh2tg4	109	9	COO	COO	NNP
cord-310847-63gh2tg4	109	10	−	−	NNP
cord-310847-63gh2tg4	109	11	in	in	IN
cord-310847-63gh2tg4	109	12	the	the	DT
cord-310847-63gh2tg4	109	13	side	side	NN
cord-310847-63gh2tg4	109	14	chain	chain	NN
cord-310847-63gh2tg4	109	15	of	of	IN
cord-310847-63gh2tg4	109	16	glutamic	glutamic	NN
cord-310847-63gh2tg4	109	17	and	and	CC
cord-310847-63gh2tg4	109	18	aspartic	aspartic	JJ
cord-310847-63gh2tg4	109	19	acids	acid	NNS
cord-310847-63gh2tg4	109	20	and	and	CC
cord-310847-63gh2tg4	109	21	NH	NH	NNP
cord-310847-63gh2tg4	109	22	3	3	CD
cord-310847-63gh2tg4	109	23	+	+	SYM
cord-310847-63gh2tg4	109	24	in	in	IN
cord-310847-63gh2tg4	109	25	the	the	DT
cord-310847-63gh2tg4	109	26	side	side	NN
cord-310847-63gh2tg4	109	27	chains	chain	NNS
cord-310847-63gh2tg4	109	28	of	of	IN
cord-310847-63gh2tg4	109	29	lysines	lysine	NNS
cord-310847-63gh2tg4	109	30	and	and	CC
cord-310847-63gh2tg4	109	31	arginines	arginines	NNP
cord-310847-63gh2tg4	109	32	.	.	.
cord-310847-63gh2tg4	110	1	Hydrogen	hydrogen	NN
cord-310847-63gh2tg4	110	2	bond	bond	NN
cord-310847-63gh2tg4	110	3	(	(	-LRB-
cord-310847-63gh2tg4	110	4	H	h	NN
cord-310847-63gh2tg4	110	5	-	-	HYPH
cord-310847-63gh2tg4	110	6	bond	bond	NN
cord-310847-63gh2tg4	110	7	)	)	-RRB-
cord-310847-63gh2tg4	110	8	is	be	VBZ
cord-310847-63gh2tg4	110	9	another	another	DT
cord-310847-63gh2tg4	110	10	non	non	JJ
cord-310847-63gh2tg4	110	11	-	-	JJ
cord-310847-63gh2tg4	110	12	covalent	covalent	JJ
cord-310847-63gh2tg4	110	13	bond	bond	NN
cord-310847-63gh2tg4	110	14	.	.	.
cord-310847-63gh2tg4	111	1	This	this	DT
cord-310847-63gh2tg4	111	2	interaction	interaction	NN
cord-310847-63gh2tg4	111	3	depends	depend	VBZ
cord-310847-63gh2tg4	111	4	on	on	IN
cord-310847-63gh2tg4	111	5	the	the	DT
cord-310847-63gh2tg4	111	6	sharing	sharing	NN
cord-310847-63gh2tg4	111	7	of	of	IN
cord-310847-63gh2tg4	111	8	one	one	CD
cord-310847-63gh2tg4	111	9	hydrogen	hydrogen	NN
cord-310847-63gh2tg4	111	10	atom	atom	NN
cord-310847-63gh2tg4	111	11	(	(	-LRB-
cord-310847-63gh2tg4	111	12	H	h	NN
cord-310847-63gh2tg4	111	13	-	-	HYPH
cord-310847-63gh2tg4	111	14	atom	atom	NN
cord-310847-63gh2tg4	111	15	)	)	-RRB-
cord-310847-63gh2tg4	111	16	between	between	IN
cord-310847-63gh2tg4	111	17	two	two	CD
cord-310847-63gh2tg4	111	18	other	other	JJ
cord-310847-63gh2tg4	111	19	atoms	atom	NNS
cord-310847-63gh2tg4	111	20	,	,	,
cord-310847-63gh2tg4	111	21	where	where	WRB
cord-310847-63gh2tg4	111	22	the	the	DT
cord-310847-63gh2tg4	111	23	H	h	NN
cord-310847-63gh2tg4	111	24	-	-	HYPH
cord-310847-63gh2tg4	111	25	atom	atom	NN
cord-310847-63gh2tg4	111	26	has	have	VBZ
cord-310847-63gh2tg4	111	27	a	a	DT
cord-310847-63gh2tg4	111	28	covalent	covalent	JJ
cord-310847-63gh2tg4	111	29	bond	bond	NN
cord-310847-63gh2tg4	111	30	to	to	IN
cord-310847-63gh2tg4	111	31	one	one	CD
cord-310847-63gh2tg4	111	32	of	of	IN
cord-310847-63gh2tg4	111	33	them	-PRON-	PRP
cord-310847-63gh2tg4	111	34	(	(	-LRB-
cord-310847-63gh2tg4	111	35	which	which	WDT
cord-310847-63gh2tg4	111	36	therefore	therefore	RB
cord-310847-63gh2tg4	111	37	serves	serve	VBZ
cord-310847-63gh2tg4	111	38	as	as	IN
cord-310847-63gh2tg4	111	39	the	the	DT
cord-310847-63gh2tg4	111	40	H	h	NN
cord-310847-63gh2tg4	111	41	-	-	HYPH
cord-310847-63gh2tg4	111	42	bond	bond	NN
cord-310847-63gh2tg4	111	43	donor	donor	NN
cord-310847-63gh2tg4	111	44	)	)	-RRB-
cord-310847-63gh2tg4	111	45	,	,	,
cord-310847-63gh2tg4	111	46	and	and	CC
cord-310847-63gh2tg4	111	47	where	where	WRB
cord-310847-63gh2tg4	111	48	the	the	DT
cord-310847-63gh2tg4	111	49	other	other	JJ
cord-310847-63gh2tg4	111	50	atom	atom	NN
cord-310847-63gh2tg4	111	51	,	,	,
cord-310847-63gh2tg4	111	52	to	to	TO
cord-310847-63gh2tg4	111	53	which	which	WDT
cord-310847-63gh2tg4	111	54	the	the	DT
cord-310847-63gh2tg4	111	55	H	H	NNP
cord-310847-63gh2tg4	111	56	-	-	HYPH
cord-310847-63gh2tg4	111	57	atom	atom	NN
cord-310847-63gh2tg4	111	58	has	have	VBZ
cord-310847-63gh2tg4	111	59	a	a	DT
cord-310847-63gh2tg4	111	60	weaker	weak	JJR
cord-310847-63gh2tg4	111	61	bond	bond	NN
cord-310847-63gh2tg4	111	62	,	,	,
cord-310847-63gh2tg4	111	63	serves	serve	VBZ
cord-310847-63gh2tg4	111	64	as	as	IN
cord-310847-63gh2tg4	111	65	the	the	DT
cord-310847-63gh2tg4	111	66	acceptor	acceptor	NN
cord-310847-63gh2tg4	111	67	,	,	,
cord-310847-63gh2tg4	111	68	A.	A.	NNP
cord-310847-63gh2tg4	111	69	Hydrogen	Hydrogen	NNP
cord-310847-63gh2tg4	111	70	bond	bond	NN
cord-310847-63gh2tg4	111	71	is	be	VBZ
cord-310847-63gh2tg4	111	72	weaker	weak	JJR
cord-310847-63gh2tg4	111	73	than	than	IN
cord-310847-63gh2tg4	111	74	a	a	DT
cord-310847-63gh2tg4	111	75	covalent	covalent	JJ
cord-310847-63gh2tg4	111	76	bond	bond	NN
cord-310847-63gh2tg4	111	77	but	but	CC
cord-310847-63gh2tg4	111	78	stronger	strong	JJR
cord-310847-63gh2tg4	111	79	than	than	IN
cord-310847-63gh2tg4	111	80	a	a	DT
cord-310847-63gh2tg4	111	81	van	van	NNP
cord-310847-63gh2tg4	111	82	der	der	NNP
cord-310847-63gh2tg4	111	83	Waals	Waals	NNP
cord-310847-63gh2tg4	111	84	bond	bond	NN
cord-310847-63gh2tg4	111	85	.	.	.
cord-310847-63gh2tg4	112	1	Similar	similar	JJ
cord-310847-63gh2tg4	112	2	to	to	IN
cord-310847-63gh2tg4	112	3	electrostatic	electrostatic	JJ
cord-310847-63gh2tg4	112	4	interactions	interaction	NNS
cord-310847-63gh2tg4	112	5	,	,	,
cord-310847-63gh2tg4	112	6	H	h	NN
cord-310847-63gh2tg4	112	7	-	-	HYPH
cord-310847-63gh2tg4	112	8	bonds	bond	NNS
cord-310847-63gh2tg4	112	9	can	can	MD
cord-310847-63gh2tg4	112	10	easily	easily	RB
cord-310847-63gh2tg4	112	11	be	be	VB
cord-310847-63gh2tg4	112	12	broken	break	VBN
cord-310847-63gh2tg4	112	13	and	and	CC
cord-310847-63gh2tg4	112	14	reformed	reform	VBN
cord-310847-63gh2tg4	112	15	.	.	.
cord-310847-63gh2tg4	113	1	Among	among	IN
cord-310847-63gh2tg4	113	2	established	establish	VBN
cord-310847-63gh2tg4	113	3	geometrical	geometrical	JJ
cord-310847-63gh2tg4	113	4	criteria	criterion	NNS
cord-310847-63gh2tg4	113	5	for	for	IN
cord-310847-63gh2tg4	113	6	H	h	NN
cord-310847-63gh2tg4	113	7	-	-	HYPH
cord-310847-63gh2tg4	113	8	bond	bond	NN
cord-310847-63gh2tg4	113	9	are	be	VBP
cord-310847-63gh2tg4	113	10	a	a	DT
cord-310847-63gh2tg4	113	11	set	set	NN
cord-310847-63gh2tg4	113	12	of	of	IN
cord-310847-63gh2tg4	113	13	optimal	optimal	JJ
cord-310847-63gh2tg4	113	14	distances	distance	NNS
cord-310847-63gh2tg4	113	15	between	between	IN
cord-310847-63gh2tg4	113	16	the	the	DT
cord-310847-63gh2tg4	113	17	non	non	JJ
cord-310847-63gh2tg4	113	18	-	-	JJ
cord-310847-63gh2tg4	113	19	H	h	JJ
cord-310847-63gh2tg4	113	20	atom	atom	NN
cord-310847-63gh2tg4	113	21	of	of	IN
cord-310847-63gh2tg4	113	22	donor	donor	NN
cord-310847-63gh2tg4	113	23	and	and	CC
cord-310847-63gh2tg4	113	24	acceptor	acceptor	NN
cord-310847-63gh2tg4	114	1	(	(	-LRB-
cord-310847-63gh2tg4	114	2	Dono	Dono	NNP
cord-310847-63gh2tg4	114	3	-	-	HYPH
cord-310847-63gh2tg4	114	4	Acceptor	Acceptor	NNP
cord-310847-63gh2tg4	114	5	<	<	XX
cord-310847-63gh2tg4	114	6	3.9	3.9	CD
cord-310847-63gh2tg4	114	7	Å	å	NN
cord-310847-63gh2tg4	114	8	)	)	-RRB-
cord-310847-63gh2tg4	114	9	and	and	CC
cord-310847-63gh2tg4	114	10	between	between	IN
cord-310847-63gh2tg4	114	11	the	the	DT
cord-310847-63gh2tg4	114	12	H	h	NN
cord-310847-63gh2tg4	114	13	atom	atom	NN
cord-310847-63gh2tg4	114	14	of	of	IN
cord-310847-63gh2tg4	114	15	donor	donor	NN
cord-310847-63gh2tg4	114	16	and	and	CC
cord-310847-63gh2tg4	114	17	acceptor	acceptor	NN
cord-310847-63gh2tg4	114	18	(	(	-LRB-
cord-310847-63gh2tg4	114	19	H	H	NNP
cord-310847-63gh2tg4	114	20	-	-	HYPH
cord-310847-63gh2tg4	114	21	Acceptor	Acceptor	NNP
cord-310847-63gh2tg4	114	22	<	<	XX
cord-310847-63gh2tg4	114	23	2.5	2.5	CD
cord-310847-63gh2tg4	114	24	Å	å	NN
cord-310847-63gh2tg4	114	25	)	)	-RRB-
cord-310847-63gh2tg4	114	26	.	.	.
cord-310847-63gh2tg4	115	1	65	65	CD
cord-310847-63gh2tg4	116	1	Being	be	VBG
cord-310847-63gh2tg4	116	2	negatively	negatively	RB
cord-310847-63gh2tg4	116	3	charged	charge	VBN
cord-310847-63gh2tg4	116	4	at	at	IN
cord-310847-63gh2tg4	116	5	physiological	physiological	JJ
cord-310847-63gh2tg4	116	6	pH	ph	NN
cord-310847-63gh2tg4	116	7	,	,	,
cord-310847-63gh2tg4	116	8	glutamic	glutamic	NN
cord-310847-63gh2tg4	116	9	acid	acid	NN
cord-310847-63gh2tg4	116	10	can	can	MD
cord-310847-63gh2tg4	116	11	serve	serve	VB
cord-310847-63gh2tg4	116	12	as	as	IN
cord-310847-63gh2tg4	116	13	a	a	DT
cord-310847-63gh2tg4	116	14	hydrogen	hydrogen	NN
cord-310847-63gh2tg4	116	15	bond	bond	NN
cord-310847-63gh2tg4	116	16	acceptor	acceptor	NN
cord-310847-63gh2tg4	116	17	,	,	,
cord-310847-63gh2tg4	116	18	whereas	whereas	IN
cord-310847-63gh2tg4	116	19	at	at	IN
cord-310847-63gh2tg4	116	20	acidic	acidic	JJ
cord-310847-63gh2tg4	116	21	pH	ph	NN
cord-310847-63gh2tg4	116	22	,	,	,
cord-310847-63gh2tg4	116	23	it	-PRON-	PRP
cord-310847-63gh2tg4	116	24	also	also	RB
cord-310847-63gh2tg4	116	25	can	can	MD
cord-310847-63gh2tg4	116	26	be	be	VB
cord-310847-63gh2tg4	116	27	a	a	DT
cord-310847-63gh2tg4	116	28	hydrogen	hydrogen	NN
cord-310847-63gh2tg4	116	29	bond	bond	NN
cord-310847-63gh2tg4	116	30	donor	donor	NN
cord-310847-63gh2tg4	116	31	.	.	.
cord-310847-63gh2tg4	117	1	Glutamic	glutamic	NN
cord-310847-63gh2tg4	117	2	acid	acid	NN
cord-310847-63gh2tg4	117	3	in	in	IN
cord-310847-63gh2tg4	117	4	the	the	DT
cord-310847-63gh2tg4	117	5	Ramachandran	Ramachandran	NNP
cord-310847-63gh2tg4	117	6	plot	plot	NN
cord-310847-63gh2tg4	117	7	.	.	.
cord-310847-63gh2tg4	118	1	The	the	DT
cord-310847-63gh2tg4	118	2	structure	structure	NN
cord-310847-63gh2tg4	118	3	of	of	IN
cord-310847-63gh2tg4	118	4	a	a	DT
cord-310847-63gh2tg4	118	5	protein	protein	NN
cord-310847-63gh2tg4	118	6	can	can	MD
cord-310847-63gh2tg4	118	7	be	be	VB
cord-310847-63gh2tg4	118	8	described	describe	VBN
cord-310847-63gh2tg4	118	9	using	use	VBG
cord-310847-63gh2tg4	118	10	torsion	torsion	NN
cord-310847-63gh2tg4	118	11	angles	angle	NNS
cord-310847-63gh2tg4	118	12	-	-	HYPH
cord-310847-63gh2tg4	118	13	φ	φ	NN
cord-310847-63gh2tg4	118	14	and	and	CC
cord-310847-63gh2tg4	118	15	ψ	ψ	NN
cord-310847-63gh2tg4	118	16	-	-	:
cord-310847-63gh2tg4	118	17	of	of	IN
cord-310847-63gh2tg4	118	18	its	-PRON-	PRP$
cord-310847-63gh2tg4	118	19	backbone	backbone	NN
cord-310847-63gh2tg4	118	20	that	that	WDT
cord-310847-63gh2tg4	118	21	provides	provide	VBZ
cord-310847-63gh2tg4	118	22	a	a	DT
cord-310847-63gh2tg4	118	23	simple	simple	JJ
cord-310847-63gh2tg4	118	24	view	view	NN
cord-310847-63gh2tg4	118	25	of	of	IN
cord-310847-63gh2tg4	118	26	the	the	DT
cord-310847-63gh2tg4	118	27	conformation	conformation	NN
cord-310847-63gh2tg4	118	28	of	of	IN
cord-310847-63gh2tg4	118	29	a	a	DT
cord-310847-63gh2tg4	118	30	protein	protein	NN
cord-310847-63gh2tg4	118	31	.	.	.
cord-310847-63gh2tg4	119	1	In	in	IN
cord-310847-63gh2tg4	119	2	sequence	sequence	NN
cord-310847-63gh2tg4	119	3	order	order	NN
cord-310847-63gh2tg4	119	4	,	,	,
cord-310847-63gh2tg4	119	5	φ	φ	NN
cord-310847-63gh2tg4	119	6	is	be	VBZ
cord-310847-63gh2tg4	119	7	the	the	DT
cord-310847-63gh2tg4	119	8	N	N	NNP
cord-310847-63gh2tg4	119	9	i-1	i-1	NN
cord-310847-63gh2tg4	119	10	-C	-C	VBZ
cord-310847-63gh2tg4	120	1	i	i	PRP
cord-310847-63gh2tg4	120	2	-Cα	-Cα	NNP
cord-310847-63gh2tg4	121	1	i	i	PRP
cord-310847-63gh2tg4	121	2	-N	-N	NFP
cord-310847-63gh2tg4	122	1	i	i	PRP
cord-310847-63gh2tg4	122	2	torsion	torsion	NN
cord-310847-63gh2tg4	122	3	angle	angle	NN
cord-310847-63gh2tg4	122	4	,	,	,
cord-310847-63gh2tg4	122	5	and	and	CC
cord-310847-63gh2tg4	122	6	ψ	ψ	NN
cord-310847-63gh2tg4	122	7	is	be	VBZ
cord-310847-63gh2tg4	122	8	the	the	DT
cord-310847-63gh2tg4	122	9	C	C	NNP
cord-310847-63gh2tg4	123	1	i	i	PRP
cord-310847-63gh2tg4	124	1	-Cα	-Cα	NNP
cord-310847-63gh2tg4	125	1	i	i	PRP
cord-310847-63gh2tg4	125	2	-N	-N	NFP
cord-310847-63gh2tg4	126	1	i	i	PRP
cord-310847-63gh2tg4	127	1	-C	-c	ADD
cord-310847-63gh2tg4	127	2	i+1	i+1	ADD
cord-310847-63gh2tg4	128	1	torsion	torsion	NN
cord-310847-63gh2tg4	128	2	angle	angle	NN
cord-310847-63gh2tg4	128	3	.	.	.
cord-310847-63gh2tg4	129	1	Since	since	IN
cord-310847-63gh2tg4	129	2	most	most	JJS
cord-310847-63gh2tg4	129	3	combinations	combination	NNS
cord-310847-63gh2tg4	129	4	of	of	IN
cord-310847-63gh2tg4	129	5	φ	φ	NN
cord-310847-63gh2tg4	129	6	and	and	CC
cord-310847-63gh2tg4	129	7	ψ	ψ	NNP
cord-310847-63gh2tg4	129	8	are	be	VBP
cord-310847-63gh2tg4	129	9	sterically	sterically	RB
cord-310847-63gh2tg4	129	10	forbidden	forbid	VBN
cord-310847-63gh2tg4	129	11	,	,	,
cord-310847-63gh2tg4	129	12	the	the	DT
cord-310847-63gh2tg4	129	13	2D	2d	JJ
cord-310847-63gh2tg4	129	14	plot	plot	NN
cord-310847-63gh2tg4	129	15	of	of	IN
cord-310847-63gh2tg4	129	16	the	the	DT
cord-310847-63gh2tg4	129	17	torsion	torsion	NN
cord-310847-63gh2tg4	129	18	angles	angle	NNS
cord-310847-63gh2tg4	129	19	of	of	IN
cord-310847-63gh2tg4	129	20	the	the	DT
cord-310847-63gh2tg4	129	21	protein	protein	NN
cord-310847-63gh2tg4	129	22	backbone	backbone	NN
cord-310847-63gh2tg4	129	23	,	,	,
cord-310847-63gh2tg4	129	24	known	know	VBN
cord-310847-63gh2tg4	129	25	as	as	IN
cord-310847-63gh2tg4	129	26	the	the	DT
cord-310847-63gh2tg4	129	27	Ramachandran	Ramachandran	NNP
cord-310847-63gh2tg4	129	28	plot	plot	NN
cord-310847-63gh2tg4	129	29	,	,	,
cord-310847-63gh2tg4	129	30	61	61	CD
cord-310847-63gh2tg4	129	31	provides	provide	VBZ
cord-310847-63gh2tg4	129	32	a	a	DT
cord-310847-63gh2tg4	129	33	simple	simple	JJ
cord-310847-63gh2tg4	129	34	view	view	NN
cord-310847-63gh2tg4	129	35	of	of	IN
cord-310847-63gh2tg4	129	36	the	the	DT
cord-310847-63gh2tg4	129	37	conformation	conformation	NN
cord-310847-63gh2tg4	129	38	of	of	IN
cord-310847-63gh2tg4	129	39	a	a	DT
cord-310847-63gh2tg4	129	40	protein	protein	NN
cord-310847-63gh2tg4	129	41	,	,	,
cord-310847-63gh2tg4	129	42	since	since	IN
cord-310847-63gh2tg4	129	43	the	the	DT
cord-310847-63gh2tg4	129	44	φ	φ	NN
cord-310847-63gh2tg4	129	45	-	-	HYPH
cord-310847-63gh2tg4	129	46	ψ	ψ	JJS
cord-310847-63gh2tg4	129	47	angles	angle	NNS
cord-310847-63gh2tg4	129	48	cluster	cluster	JJ
cord-310847-63gh2tg4	129	49	into	into	IN
cord-310847-63gh2tg4	129	50	distinct	distinct	JJ
cord-310847-63gh2tg4	129	51	regions	region	NNS
cord-310847-63gh2tg4	129	52	in	in	IN
cord-310847-63gh2tg4	129	53	the	the	DT
cord-310847-63gh2tg4	129	54	Ramachandran	Ramachandran	NNP
cord-310847-63gh2tg4	129	55	plot	plot	NN
cord-310847-63gh2tg4	129	56	,	,	,
cord-310847-63gh2tg4	129	57	where	where	WRB
cord-310847-63gh2tg4	129	58	each	each	DT
cord-310847-63gh2tg4	129	59	region	region	NN
cord-310847-63gh2tg4	129	60	corresponds	correspond	VBZ
cord-310847-63gh2tg4	129	61	to	to	IN
cord-310847-63gh2tg4	129	62	a	a	DT
cord-310847-63gh2tg4	129	63	particular	particular	JJ
cord-310847-63gh2tg4	129	64	secondary	secondary	JJ
cord-310847-63gh2tg4	129	65	structure	structure	NN
cord-310847-63gh2tg4	129	66	.	.	.
cord-310847-63gh2tg4	130	1	In	in	IN
cord-310847-63gh2tg4	130	2	the	the	DT
cord-310847-63gh2tg4	130	3	generic	generic	JJ
cord-310847-63gh2tg4	130	4	Ramachandran	Ramachandran	NNP
cord-310847-63gh2tg4	130	5	plot	plot	NN
cord-310847-63gh2tg4	130	6	(	(	-LRB-
cord-310847-63gh2tg4	130	7	see	see	VB
cord-310847-63gh2tg4	130	8	Fig	Fig	NNP
cord-310847-63gh2tg4	130	9	.	.	.
cord-310847-63gh2tg4	130	10	2B	2b	CD
cord-310847-63gh2tg4	130	11	)	)	-RRB-
cord-310847-63gh2tg4	131	1	that	that	DT
cord-310847-63gh2tg4	131	2	refers	refer	VBZ
cord-310847-63gh2tg4	131	3	to	to	IN
cord-310847-63gh2tg4	131	4	the	the	DT
cord-310847-63gh2tg4	131	5	18	18	CD
cord-310847-63gh2tg4	131	6	non	non	JJ
cord-310847-63gh2tg4	131	7	-	-	JJ
cord-310847-63gh2tg4	131	8	glycine	glycine	JJ
cord-310847-63gh2tg4	131	9	and	and	CC
cord-310847-63gh2tg4	131	10	non	non	JJ
cord-310847-63gh2tg4	131	11	-	-	JJ
cord-310847-63gh2tg4	131	12	proline	proline	JJ
cord-310847-63gh2tg4	131	13	amino	amino	NN
cord-310847-63gh2tg4	131	14	acids	acid	NNS
cord-310847-63gh2tg4	131	15	,	,	,
cord-310847-63gh2tg4	131	16	there	there	EX
cord-310847-63gh2tg4	131	17	are	be	VBP
cord-310847-63gh2tg4	131	18	four	four	CD
cord-310847-63gh2tg4	131	19	distinct	distinct	JJ
cord-310847-63gh2tg4	131	20	regions	region	NNS
cord-310847-63gh2tg4	131	21	of	of	IN
cord-310847-63gh2tg4	131	22	density	density	NN
cord-310847-63gh2tg4	131	23	(	(	-LRB-
cord-310847-63gh2tg4	131	24	the	the	DT
cord-310847-63gh2tg4	131	25	α	α	NN
cord-310847-63gh2tg4	131	26	(	(	-LRB-
cord-310847-63gh2tg4	131	27	right	right	RB
cord-310847-63gh2tg4	131	28	-	-	HYPH
cord-310847-63gh2tg4	131	29	handed	handed	JJ
cord-310847-63gh2tg4	131	30	α	α	NN
cord-310847-63gh2tg4	131	31	-	-	HYPH
cord-310847-63gh2tg4	131	32	helix	helix	NN
cord-310847-63gh2tg4	131	33	region	region	NN
cord-310847-63gh2tg4	131	34	)	)	-RRB-
cord-310847-63gh2tg4	131	35	,	,	,
cord-310847-63gh2tg4	131	36	α	α	NNP
cord-310847-63gh2tg4	131	37	L	l	NN
cord-310847-63gh2tg4	131	38	(	(	-LRB-
cord-310847-63gh2tg4	131	39	mirror	mirror	NN
cord-310847-63gh2tg4	131	40	image	image	NN
cord-310847-63gh2tg4	131	41	of	of	IN
cord-310847-63gh2tg4	131	42	α	α	NNP
cord-310847-63gh2tg4	131	43	)	)	-RRB-
cord-310847-63gh2tg4	131	44	,	,	,
cord-310847-63gh2tg4	131	45	β	β	NNP
cord-310847-63gh2tg4	131	46	S	S	NNP
cord-310847-63gh2tg4	131	47	(	(	-LRB-
cord-310847-63gh2tg4	131	48	region	region	NN
cord-310847-63gh2tg4	131	49	largely	largely	RB
cord-310847-63gh2tg4	131	50	involved	involve	VBN
cord-310847-63gh2tg4	131	51	in	in	IN
cord-310847-63gh2tg4	131	52	β	β	NN
cord-310847-63gh2tg4	131	53	-	-	HYPH
cord-310847-63gh2tg4	131	54	sheet	sheet	NN
cord-310847-63gh2tg4	131	55	formation	formation	NN
cord-310847-63gh2tg4	131	56	)	)	-RRB-
cord-310847-63gh2tg4	131	57	and	and	CC
cord-310847-63gh2tg4	131	58	β	β	NN
cord-310847-63gh2tg4	131	59	P	p	NN
cord-310847-63gh2tg4	131	60	(	(	-LRB-
cord-310847-63gh2tg4	131	61	region	region	NN
cord-310847-63gh2tg4	131	62	associated	associate	VBN
cord-310847-63gh2tg4	131	63	with	with	IN
cord-310847-63gh2tg4	131	64	extended	extended	JJ
cord-310847-63gh2tg4	131	65	polyproline	polyproline	NN
cord-310847-63gh2tg4	131	66	-	-	HYPH
cord-310847-63gh2tg4	131	67	like	like	JJ
cord-310847-63gh2tg4	131	68	helices	helix	NNS
cord-310847-63gh2tg4	131	69	but	but	CC
cord-310847-63gh2tg4	131	70	also	also	RB
cord-310847-63gh2tg4	131	71	observed	observe	VBD
cord-310847-63gh2tg4	131	72	in	in	IN
cord-310847-63gh2tg4	131	73	β	β	NN
cord-310847-63gh2tg4	131	74	-	-	HYPH
cord-310847-63gh2tg4	131	75	sheet	sheet	NN
cord-310847-63gh2tg4	131	76	)	)	-RRB-
cord-310847-63gh2tg4	131	77	.	.	.
cord-310847-63gh2tg4	132	1	The	the	DT
cord-310847-63gh2tg4	132	2	shape	shape	NN
cord-310847-63gh2tg4	132	3	of	of	IN
cord-310847-63gh2tg4	132	4	the	the	DT
cord-310847-63gh2tg4	132	5	generic	generic	JJ
cord-310847-63gh2tg4	132	6	Ramachandran	Ramachandran	NNP
cord-310847-63gh2tg4	132	7	plot	plot	NN
cord-310847-63gh2tg4	132	8	is	be	VBZ
cord-310847-63gh2tg4	132	9	determined	determine	VBN
cord-310847-63gh2tg4	132	10	mainly	mainly	RB
cord-310847-63gh2tg4	132	11	by	by	IN
cord-310847-63gh2tg4	132	12	the	the	DT
cord-310847-63gh2tg4	132	13	presence	presence	NN
cord-310847-63gh2tg4	132	14	of	of	IN
cord-310847-63gh2tg4	132	15	specific	specific	JJ
cord-310847-63gh2tg4	132	16	steric	steric	JJ
cord-310847-63gh2tg4	132	17	clashes	clash	NNS
cord-310847-63gh2tg4	132	18	61	61	CD
cord-310847-63gh2tg4	132	19	and	and	CC
cord-310847-63gh2tg4	132	20	backbone	backbone	NN
cord-310847-63gh2tg4	132	21	dipole	dipole	NN
cord-310847-63gh2tg4	132	22	-	-	HYPH
cord-310847-63gh2tg4	132	23	dipole	dipole	NN
cord-310847-63gh2tg4	132	24	interactions	interaction	NNS
cord-310847-63gh2tg4	132	25	.	.	.
cord-310847-63gh2tg4	133	1	[	[	-LRB-
cord-310847-63gh2tg4	133	2	62	62	CD
cord-310847-63gh2tg4	133	3	]	]	-RRB-
cord-310847-63gh2tg4	133	4	[	[	-LRB-
cord-310847-63gh2tg4	133	5	63	63	CD
cord-310847-63gh2tg4	133	6	]	]	-RRB-
cord-310847-63gh2tg4	133	7	[	[	-LRB-
cord-310847-63gh2tg4	133	8	64	64	CD
cord-310847-63gh2tg4	133	9	]	]	-RRB-
cord-310847-63gh2tg4	133	10	Glutamic	glutamic	NN
cord-310847-63gh2tg4	133	11	acid	acid	NN
cord-310847-63gh2tg4	133	12	in	in	IN
cord-310847-63gh2tg4	133	13	electrostatic	electrostatic	JJ
cord-310847-63gh2tg4	133	14	interactions	interaction	NNS
cord-310847-63gh2tg4	133	15	and	and	CC
cord-310847-63gh2tg4	133	16	hydrogen	hydrogen	NN
cord-310847-63gh2tg4	133	17	bonds	bond	NNS
cord-310847-63gh2tg4	133	18	.	.	.
cord-310847-63gh2tg4	134	1	Glutamic	glutamic	NN
cord-310847-63gh2tg4	134	2	acid	acid	NN
cord-310847-63gh2tg4	134	3	participates	participate	VBZ
cord-310847-63gh2tg4	134	4	in	in	IN
cord-310847-63gh2tg4	134	5	electrostatic	electrostatic	JJ
cord-310847-63gh2tg4	134	6	interactions	interaction	NNS
cord-310847-63gh2tg4	134	7	,	,	,
cord-310847-63gh2tg4	134	8	which	which	WDT
cord-310847-63gh2tg4	134	9	are	be	VBP
cord-310847-63gh2tg4	134	10	also	also	RB
cord-310847-63gh2tg4	134	11	known	know	VBN
cord-310847-63gh2tg4	134	12	as	as	IN
cord-310847-63gh2tg4	134	13	ionic	ionic	JJ
cord-310847-63gh2tg4	134	14	bonds	bond	NNS
cord-310847-63gh2tg4	134	15	,	,	,
cord-310847-63gh2tg4	134	16	or	or	CC
cord-310847-63gh2tg4	134	17	salt	salt	NN
cord-310847-63gh2tg4	134	18	bridges	bridge	NNS
cord-310847-63gh2tg4	134	19	,	,	,
cord-310847-63gh2tg4	134	20	or	or	CC
cord-310847-63gh2tg4	134	21	salt	salt	NN
cord-310847-63gh2tg4	134	22	GCN4	GCN4	NNP
cord-310847-63gh2tg4	134	23	leucine	leucine	NN
cord-310847-63gh2tg4	134	24	zipper	zipper	NN
cord-310847-63gh2tg4	134	25	dimer	dimer	NN
cord-310847-63gh2tg4	134	26	revealed	reveal	VBD
cord-310847-63gh2tg4	134	27	that	that	IN
cord-310847-63gh2tg4	134	28	the	the	DT
cord-310847-63gh2tg4	134	29	free	free	JJ
cord-310847-63gh2tg4	134	30	energy	energy	NN
cord-310847-63gh2tg4	134	31	of	of	IN
cord-310847-63gh2tg4	134	32	helix	helix	NN
cord-310847-63gh2tg4	134	33	stabilization	stabilization	NN
cord-310847-63gh2tg4	134	34	associated	associate	VBN
cord-310847-63gh2tg4	134	35	with	with	IN
cord-310847-63gh2tg4	134	36	the	the	DT
cord-310847-63gh2tg4	134	37	hydrogen	hydrogen	NN
cord-310847-63gh2tg4	134	38	-	-	HYPH
cord-310847-63gh2tg4	134	39	bonding	bonding	NN
cord-310847-63gh2tg4	134	40	and	and	CC
cord-310847-63gh2tg4	134	41	hydrophobic	hydrophobic	JJ
cord-310847-63gh2tg4	134	42	interactions	interaction	NNS
cord-310847-63gh2tg4	134	43	in	in	IN
cord-310847-63gh2tg4	134	44	this	this	DT
cord-310847-63gh2tg4	134	45	capping	cap	VBG
cord-310847-63gh2tg4	134	46	structure	structure	NN
cord-310847-63gh2tg4	134	47	is	be	VBZ
cord-310847-63gh2tg4	134	48	−1.2	−1.2	NN
cord-310847-63gh2tg4	134	49	kcal/	kcal/	CD
cord-310847-63gh2tg4	134	50	mol	mol	NN
cord-310847-63gh2tg4	134	51	,	,	,
cord-310847-63gh2tg4	134	52	illustrating	illustrate	VBG
cord-310847-63gh2tg4	134	53	that	that	IN
cord-310847-63gh2tg4	134	54	helix	helix	NN
cord-310847-63gh2tg4	134	55	capping	capping	NN
cord-310847-63gh2tg4	134	56	might	may	MD
cord-310847-63gh2tg4	134	57	play	play	VB
cord-310847-63gh2tg4	134	58	a	a	DT
cord-310847-63gh2tg4	134	59	significant	significant	JJ
cord-310847-63gh2tg4	134	60	role	role	NN
cord-310847-63gh2tg4	134	61	in	in	IN
cord-310847-63gh2tg4	134	62	protein	protein	NN
cord-310847-63gh2tg4	134	63	folding	folding	NN
cord-310847-63gh2tg4	134	64	.	.	.
cord-310847-63gh2tg4	135	1	72	72	CD
cord-310847-63gh2tg4	136	1	Based	base	VBN
cord-310847-63gh2tg4	136	2	on	on	IN
cord-310847-63gh2tg4	136	3	the	the	DT
cord-310847-63gh2tg4	136	4	analysis	analysis	NN
cord-310847-63gh2tg4	136	5	of	of	IN
cord-310847-63gh2tg4	136	6	431	431	CD
cord-310847-63gh2tg4	136	7	α	α	NN
cord-310847-63gh2tg4	136	8	-	-	HYPH
cord-310847-63gh2tg4	136	9	helices	helix	NNS
cord-310847-63gh2tg4	136	10	the	the	DT
cord-310847-63gh2tg4	136	11	normalized	normalized	JJ
cord-310847-63gh2tg4	136	12	frequencies	frequency	NNS
cord-310847-63gh2tg4	136	13	for	for	IN
cord-310847-63gh2tg4	136	14	finding	find	VBG
cord-310847-63gh2tg4	136	15	particular	particular	JJ
cord-310847-63gh2tg4	136	16	residues	residue	NNS
cord-310847-63gh2tg4	136	17	at	at	IN
cord-310847-63gh2tg4	136	18	the	the	DT
cord-310847-63gh2tg4	136	19	C	C	NNP
cord-310847-63gh2tg4	136	20	cap	cap	NN
cord-310847-63gh2tg4	136	21	position	position	NN
cord-310847-63gh2tg4	136	22	,	,	,
cord-310847-63gh2tg4	136	23	the	the	DT
cord-310847-63gh2tg4	136	24	average	average	JJ
cord-310847-63gh2tg4	136	25	fraction	fraction	NN
cord-310847-63gh2tg4	136	26	of	of	IN
cord-310847-63gh2tg4	136	27	buried	bury	VBN
cord-310847-63gh2tg4	136	28	surface	surface	NN
cord-310847-63gh2tg4	136	29	area	area	NN
cord-310847-63gh2tg4	136	30	and	and	CC
cord-310847-63gh2tg4	136	31	the	the	DT
cord-310847-63gh2tg4	136	32	hydrogen	hydrogen	NN
cord-310847-63gh2tg4	136	33	bonding	bonding	NN
cord-310847-63gh2tg4	136	34	patterns	pattern	NNS
cord-310847-63gh2tg4	136	35	of	of	IN
cord-310847-63gh2tg4	136	36	the	the	DT
cord-310847-63gh2tg4	136	37	C	C	NNP
cord-310847-63gh2tg4	136	38	cap	cap	NN
cord-310847-63gh2tg4	136	39	residue	residue	NN
cord-310847-63gh2tg4	136	40	side	side	NN
cord-310847-63gh2tg4	136	41	-	-	HYPH
cord-310847-63gh2tg4	136	42	chain	chain	NN
cord-310847-63gh2tg4	136	43	were	be	VBD
cord-310847-63gh2tg4	136	44	calculated	calculate	VBN
cord-310847-63gh2tg4	136	45	.	.	.
cord-310847-63gh2tg4	137	1	74	74	CD
cord-310847-63gh2tg4	138	1	This	this	DT
cord-310847-63gh2tg4	138	2	analysis	analysis	NN
cord-310847-63gh2tg4	138	3	revealed	reveal	VBD
cord-310847-63gh2tg4	138	4	that	that	IN
cord-310847-63gh2tg4	138	5	the	the	DT
cord-310847-63gh2tg4	138	6	residue	residue	NN
cord-310847-63gh2tg4	138	7	found	find	VBN
cord-310847-63gh2tg4	138	8	in	in	IN
cord-310847-63gh2tg4	138	9	the	the	DT
cord-310847-63gh2tg4	138	10	C	C	NNP
cord-310847-63gh2tg4	138	11	cap	cap	NN
cord-310847-63gh2tg4	138	12	position	position	NN
cord-310847-63gh2tg4	138	13	is	be	VBZ
cord-310847-63gh2tg4	138	14	on	on	IN
cord-310847-63gh2tg4	138	15	average	average	JJ
cord-310847-63gh2tg4	138	16	70	70	CD
cord-310847-63gh2tg4	138	17	%	%	NN
cord-310847-63gh2tg4	138	18	buried	bury	VBN
cord-310847-63gh2tg4	138	19	and	and	CC
cord-310847-63gh2tg4	138	20	that	that	IN
cord-310847-63gh2tg4	138	21	there	there	EX
cord-310847-63gh2tg4	138	22	is	be	VBZ
cord-310847-63gh2tg4	138	23	a	a	DT
cord-310847-63gh2tg4	138	24	noticeable	noticeable	JJ
cord-310847-63gh2tg4	138	25	correlation	correlation	NN
cord-310847-63gh2tg4	138	26	between	between	IN
cord-310847-63gh2tg4	138	27	the	the	DT
cord-310847-63gh2tg4	138	28	relative	relative	JJ
cord-310847-63gh2tg4	138	29	burial	burial	NN
cord-310847-63gh2tg4	138	30	of	of	IN
cord-310847-63gh2tg4	138	31	this	this	DT
cord-310847-63gh2tg4	138	32	residue	residue	NN
cord-310847-63gh2tg4	138	33	and	and	CC
cord-310847-63gh2tg4	138	34	its	-PRON-	PRP$
cord-310847-63gh2tg4	138	35	hydrophobicity	hydrophobicity	NN
cord-310847-63gh2tg4	138	36	.	.	.
cord-310847-63gh2tg4	139	1	74	74	CD
cord-310847-63gh2tg4	140	1	Furthermore	furthermore	RB
cord-310847-63gh2tg4	140	2	,	,	,
cord-310847-63gh2tg4	140	3	C	c	NN
cord-310847-63gh2tg4	140	4	cap	cap	NN
cord-310847-63gh2tg4	140	5	residues	residue	NNS
cord-310847-63gh2tg4	140	6	with	with	IN
cord-310847-63gh2tg4	140	7	polar	polar	JJ
cord-310847-63gh2tg4	140	8	sidechains	sidechain	NNS
cord-310847-63gh2tg4	140	9	were	be	VBD
cord-310847-63gh2tg4	140	10	shown	show	VBN
cord-310847-63gh2tg4	140	11	to	to	TO
cord-310847-63gh2tg4	140	12	be	be	VB
cord-310847-63gh2tg4	140	13	involved	involve	VBN
cord-310847-63gh2tg4	140	14	in	in	IN
cord-310847-63gh2tg4	140	15	hydrogen	hydrogen	NN
cord-310847-63gh2tg4	140	16	bonding	bonding	NN
cord-310847-63gh2tg4	140	17	,	,	,
cord-310847-63gh2tg4	140	18	where	where	WRB
cord-310847-63gh2tg4	140	19	the	the	DT
cord-310847-63gh2tg4	140	20	longer	long	JJR
cord-310847-63gh2tg4	140	21	side	side	NN
cord-310847-63gh2tg4	140	22	-	-	HYPH
cord-310847-63gh2tg4	140	23	chains	chain	NNS
cord-310847-63gh2tg4	140	24	of	of	IN
cord-310847-63gh2tg4	140	25	glutamic	glutamic	NN
cord-310847-63gh2tg4	140	26	acid	acid	NN
cord-310847-63gh2tg4	140	27	,	,	,
cord-310847-63gh2tg4	140	28	glutamin	glutamin	NN
cord-310847-63gh2tg4	140	29	,	,	,
cord-310847-63gh2tg4	140	30	arginine	arginine	NN
cord-310847-63gh2tg4	140	31	,	,	,
cord-310847-63gh2tg4	140	32	lysine	lysine	NN
cord-310847-63gh2tg4	140	33	and	and	CC
cord-310847-63gh2tg4	140	34	histidine	histidine	NN
cord-310847-63gh2tg4	140	35	form	form	NN
cord-310847-63gh2tg4	140	36	hydrogen	hydrogen	NN
cord-310847-63gh2tg4	140	37	bonds	bond	NNS
cord-310847-63gh2tg4	140	38	with	with	IN
cord-310847-63gh2tg4	140	39	residues	residue	NNS
cord-310847-63gh2tg4	140	40	located	locate	VBN
cord-310847-63gh2tg4	140	41	more	more	JJR
cord-310847-63gh2tg4	140	42	than	than	IN
cord-310847-63gh2tg4	140	43	four	four	CD
cord-310847-63gh2tg4	140	44	residues	residue	NNS
cord-310847-63gh2tg4	140	45	apart	apart	RB
cord-310847-63gh2tg4	140	46	,	,	,
cord-310847-63gh2tg4	140	47	whereas	whereas	IN
cord-310847-63gh2tg4	140	48	the	the	DT
cord-310847-63gh2tg4	140	49	shorter	short	JJR
cord-310847-63gh2tg4	140	50	side	side	NN
cord-310847-63gh2tg4	140	51	-	-	HYPH
cord-310847-63gh2tg4	140	52	chains	chain	NNS
cord-310847-63gh2tg4	140	53	Glutamic	Glutamic	NNP
cord-310847-63gh2tg4	140	54	acid	acid	NN
cord-310847-63gh2tg4	140	55	and	and	CC
cord-310847-63gh2tg4	140	56	protein	protein	NN
cord-310847-63gh2tg4	140	57	secondary	secondary	JJ
cord-310847-63gh2tg4	140	58	structure	structure	NN
cord-310847-63gh2tg4	140	59	.	.	.
cord-310847-63gh2tg4	141	1	Although	although	IN
cord-310847-63gh2tg4	141	2	protein	protein	NN
cord-310847-63gh2tg4	141	3	secondary	secondary	JJ
cord-310847-63gh2tg4	141	4	structure	structure	NN
cord-310847-63gh2tg4	141	5	is	be	VBZ
cord-310847-63gh2tg4	141	6	determined	determine	VBN
cord-310847-63gh2tg4	141	7	by	by	IN
cord-310847-63gh2tg4	141	8	hydrogen	hydrogen	NN
cord-310847-63gh2tg4	141	9	bonds	bond	NNS
cord-310847-63gh2tg4	141	10	between	between	IN
cord-310847-63gh2tg4	141	11	donor	donor	NN
cord-310847-63gh2tg4	141	12	and	and	CC
cord-310847-63gh2tg4	141	13	acceptor	acceptor	NN
cord-310847-63gh2tg4	141	14	groups	group	NNS
cord-310847-63gh2tg4	141	15	in	in	IN
cord-310847-63gh2tg4	141	16	the	the	DT
cord-310847-63gh2tg4	141	17	protein	protein	NN
cord-310847-63gh2tg4	141	18	backbone	backbone	NN
cord-310847-63gh2tg4	141	19	,	,	,
cord-310847-63gh2tg4	141	20	different	different	JJ
cord-310847-63gh2tg4	141	21	amino	amino	NN
cord-310847-63gh2tg4	141	22	acids	acid	NNS
cord-310847-63gh2tg4	141	23	are	be	VBP
cord-310847-63gh2tg4	141	24	known	know	VBN
cord-310847-63gh2tg4	141	25	to	to	TO
cord-310847-63gh2tg4	141	26	favor	favor	VB
cord-310847-63gh2tg4	141	27	the	the	DT
cord-310847-63gh2tg4	141	28	formation	formation	NN
cord-310847-63gh2tg4	141	29	of	of	IN
cord-310847-63gh2tg4	141	30	different	different	JJ
cord-310847-63gh2tg4	141	31	secondary	secondary	JJ
cord-310847-63gh2tg4	141	32	structure	structure	NN
cord-310847-63gh2tg4	141	33	elements	element	NNS
cord-310847-63gh2tg4	141	34	,	,	,
cord-310847-63gh2tg4	141	35	such	such	JJ
cord-310847-63gh2tg4	141	36	as	as	IN
cord-310847-63gh2tg4	141	37	α	α	NN
cord-310847-63gh2tg4	141	38	-	-	HYPH
cord-310847-63gh2tg4	141	39	helices	helix	NNS
cord-310847-63gh2tg4	141	40	,	,	,
cord-310847-63gh2tg4	141	41	β	β	NN
cord-310847-63gh2tg4	141	42	-	-	HYPH
cord-310847-63gh2tg4	141	43	pleated	pleated	JJ
cord-310847-63gh2tg4	141	44	sheets	sheet	NNS
cord-310847-63gh2tg4	141	45	or	or	CC
cord-310847-63gh2tg4	141	46	loops	loop	NNS
cord-310847-63gh2tg4	141	47	.	.	.
cord-310847-63gh2tg4	142	1	The	the	DT
cord-310847-63gh2tg4	142	2	α	α	NN
cord-310847-63gh2tg4	142	3	-	-	HYPH
cord-310847-63gh2tg4	142	4	helix	helix	NN
cord-310847-63gh2tg4	142	5	-	-	HYPH
cord-310847-63gh2tg4	142	6	formers	former	NNS
cord-310847-63gh2tg4	142	7	include	include	VBP
cord-310847-63gh2tg4	142	8	alanine	alanine	NN
cord-310847-63gh2tg4	142	9	,	,	,
cord-310847-63gh2tg4	142	10	cysteine	cysteine	NN
cord-310847-63gh2tg4	142	11	,	,	,
cord-310847-63gh2tg4	142	12	leucine	leucine	NN
cord-310847-63gh2tg4	142	13	,	,	,
cord-310847-63gh2tg4	142	14	methionine	methionine	NN
cord-310847-63gh2tg4	142	15	,	,	,
cord-310847-63gh2tg4	142	16	glutamic	glutamic	NN
cord-310847-63gh2tg4	142	17	acid	acid	NN
cord-310847-63gh2tg4	142	18	,	,	,
cord-310847-63gh2tg4	142	19	glutamine	glutamine	NN
cord-310847-63gh2tg4	142	20	,	,	,
cord-310847-63gh2tg4	142	21	histidine	histidine	NN
cord-310847-63gh2tg4	142	22	and	and	CC
cord-310847-63gh2tg4	142	23	lysine	lysine	NN
cord-310847-63gh2tg4	142	24	,	,	,
cord-310847-63gh2tg4	142	25	whereas	whereas	IN
cord-310847-63gh2tg4	142	26	valine	valine	NN
cord-310847-63gh2tg4	142	27	,	,	,
cord-310847-63gh2tg4	142	28	isoleucine	isoleucine	NN
cord-310847-63gh2tg4	142	29	,	,	,
cord-310847-63gh2tg4	142	30	phenylalanine	phenylalanine	NN
cord-310847-63gh2tg4	142	31	,	,	,
cord-310847-63gh2tg4	142	32	tyrosine	tyrosine	NN
cord-310847-63gh2tg4	142	33	,	,	,
cord-310847-63gh2tg4	142	34	tryptophan	tryptophan	NN
cord-310847-63gh2tg4	142	35	and	and	CC
cord-310847-63gh2tg4	142	36	threonine	threonine	NN
cord-310847-63gh2tg4	142	37	favor	favor	NN
cord-310847-63gh2tg4	142	38	β	β	NN
cord-310847-63gh2tg4	142	39	-	-	HYPH
cord-310847-63gh2tg4	142	40	structure	structure	NN
cord-310847-63gh2tg4	142	41	formation	formation	NN
cord-310847-63gh2tg4	142	42	,	,	,
cord-310847-63gh2tg4	142	43	and	and	CC
cord-310847-63gh2tg4	142	44	serine	serine	NN
cord-310847-63gh2tg4	142	45	,	,	,
cord-310847-63gh2tg4	142	46	glycine	glycine	NN
cord-310847-63gh2tg4	142	47	,	,	,
cord-310847-63gh2tg4	142	48	uncharged	uncharged	JJ
cord-310847-63gh2tg4	142	49	aspartic	aspartic	JJ
cord-310847-63gh2tg4	142	50	acid	acid	NN
cord-310847-63gh2tg4	142	51	,	,	,
cord-310847-63gh2tg4	142	52	asparagine	asparagine	NN
cord-310847-63gh2tg4	142	53	and	and	CC
cord-310847-63gh2tg4	142	54	proline	proline	NN
cord-310847-63gh2tg4	142	55	are	be	VBP
cord-310847-63gh2tg4	142	56	found	find	VBN
cord-310847-63gh2tg4	142	57	most	most	RBS
cord-310847-63gh2tg4	142	58	often	often	RB
cord-310847-63gh2tg4	142	59	in	in	IN
cord-310847-63gh2tg4	142	60	β	β	NN
cord-310847-63gh2tg4	142	61	-	-	HYPH
cord-310847-63gh2tg4	142	62	turns	turn	NNS
cord-310847-63gh2tg4	142	63	.	.	.
cord-310847-63gh2tg4	143	1	It	-PRON-	PRP
cord-310847-63gh2tg4	143	2	was	be	VBD
cord-310847-63gh2tg4	143	3	pointed	point	VBN
cord-310847-63gh2tg4	143	4	out	out	RP
cord-310847-63gh2tg4	143	5	that	that	IN
cord-310847-63gh2tg4	143	6	there	there	EX
cord-310847-63gh2tg4	143	7	is	be	VBZ
cord-310847-63gh2tg4	143	8	no	no	DT
cord-310847-63gh2tg4	143	9	apparent	apparent	JJ
cord-310847-63gh2tg4	143	10	relationship	relationship	NN
cord-310847-63gh2tg4	143	11	between	between	IN
cord-310847-63gh2tg4	143	12	the	the	DT
cord-310847-63gh2tg4	143	13	chemical	chemical	JJ
cord-310847-63gh2tg4	143	14	nature	nature	NN
cord-310847-63gh2tg4	143	15	of	of	IN
cord-310847-63gh2tg4	143	16	the	the	DT
cord-310847-63gh2tg4	143	17	amino	amino	NN
cord-310847-63gh2tg4	143	18	acid	acid	NN
cord-310847-63gh2tg4	143	19	side	side	NN
cord-310847-63gh2tg4	143	20	chain	chain	NN
cord-310847-63gh2tg4	143	21	and	and	CC
cord-310847-63gh2tg4	143	22	its	-PRON-	PRP$
cord-310847-63gh2tg4	143	23	secondary	secondary	JJ
cord-310847-63gh2tg4	143	24	structure	structure	NN
cord-310847-63gh2tg4	143	25	preferences	preference	NNS
cord-310847-63gh2tg4	143	26	.	.	.
cord-310847-63gh2tg4	144	1	For	for	IN
cord-310847-63gh2tg4	144	2	example	example	NN
cord-310847-63gh2tg4	144	3	,	,	,
cord-310847-63gh2tg4	144	4	although	although	IN
cord-310847-63gh2tg4	144	5	glutamic	glutamic	NN
cord-310847-63gh2tg4	144	6	and	and	CC
cord-310847-63gh2tg4	144	7	aspartic	aspartic	JJ
cord-310847-63gh2tg4	144	8	acids	acid	NNS
cord-310847-63gh2tg4	144	9	are	be	VBP
cord-310847-63gh2tg4	144	10	closely	closely	RB
cord-310847-63gh2tg4	144	11	related	relate	VBN
cord-310847-63gh2tg4	144	12	chemically	chemically	RB
cord-310847-63gh2tg4	144	13	,	,	,
cord-310847-63gh2tg4	144	14	glutamic	glutamic	NN
cord-310847-63gh2tg4	144	15	acid	acid	NN
cord-310847-63gh2tg4	144	16	is	be	VBZ
cord-310847-63gh2tg4	144	17	more	more	RBR
cord-310847-63gh2tg4	144	18	likely	likely	JJ
cord-310847-63gh2tg4	144	19	to	to	TO
cord-310847-63gh2tg4	144	20	be	be	VB
cord-310847-63gh2tg4	144	21	found	find	VBN
cord-310847-63gh2tg4	144	22	in	in	IN
cord-310847-63gh2tg4	144	23	helices	helix	NNS
cord-310847-63gh2tg4	144	24	and	and	CC
cord-310847-63gh2tg4	144	25	aspartic	aspartic	JJ
cord-310847-63gh2tg4	144	26	acid	acid	NN
cord-310847-63gh2tg4	144	27	is	be	VBZ
cord-310847-63gh2tg4	144	28	predominantly	predominantly	RB
cord-310847-63gh2tg4	144	29	located	locate	VBN
cord-310847-63gh2tg4	144	30	in	in	IN
cord-310847-63gh2tg4	144	31	β	β	NN
cord-310847-63gh2tg4	144	32	-	-	HYPH
cord-310847-63gh2tg4	144	33	turns	turn	NNS
cord-310847-63gh2tg4	144	34	.	.	.
cord-310847-63gh2tg4	145	1	In	in	IN
cord-310847-63gh2tg4	145	2	fact	fact	NN
cord-310847-63gh2tg4	145	3	,	,	,
cord-310847-63gh2tg4	145	4	the	the	DT
cord-310847-63gh2tg4	145	5	helical	helical	JJ
cord-310847-63gh2tg4	145	6	propensity	propensity	NN
cord-310847-63gh2tg4	145	7	of	of	IN
cord-310847-63gh2tg4	145	8	glutamic	glutamic	NN
cord-310847-63gh2tg4	145	9	acid	acid	NN
cord-310847-63gh2tg4	145	10	is	be	VBZ
cord-310847-63gh2tg4	145	11	0.40	0.40	CD
cord-310847-63gh2tg4	145	12	,	,	,
cord-310847-63gh2tg4	145	13	whereas	whereas	IN
cord-310847-63gh2tg4	145	14	aspartic	aspartic	JJ
cord-310847-63gh2tg4	145	15	acid	acid	NN
cord-310847-63gh2tg4	145	16	has	have	VBZ
cord-310847-63gh2tg4	145	17	an	an	DT
cord-310847-63gh2tg4	145	18	helical	helical	JJ
cord-310847-63gh2tg4	145	19	propensity	propensity	NN
cord-310847-63gh2tg4	145	20	of	of	IN
cord-310847-63gh2tg4	145	21	0.69	0.69	CD
cord-310847-63gh2tg4	145	22	,	,	,
cord-310847-63gh2tg4	145	23	the	the	DT
cord-310847-63gh2tg4	145	24	third	third	RB
cord-310847-63gh2tg4	145	25	largest	large	JJS
cord-310847-63gh2tg4	145	26	value	value	NN
cord-310847-63gh2tg4	145	27	after	after	IN
cord-310847-63gh2tg4	145	28	proline	proline	NN
cord-310847-63gh2tg4	145	29	and	and	CC
cord-310847-63gh2tg4	145	30	glycine	glycine	NN
cord-310847-63gh2tg4	145	31	.	.	.
cord-310847-63gh2tg4	146	1	66	66	CD
cord-310847-63gh2tg4	147	1	Note	note	VB
cord-310847-63gh2tg4	147	2	that	that	IN
cord-310847-63gh2tg4	147	3	the	the	DT
cord-310847-63gh2tg4	147	4	helical	helical	JJ
cord-310847-63gh2tg4	147	5	propensity	propensity	NN
cord-310847-63gh2tg4	147	6	is	be	VBZ
cord-310847-63gh2tg4	147	7	defined	define	VBN
cord-310847-63gh2tg4	147	8	as	as	IN
cord-310847-63gh2tg4	147	9	the	the	DT
cord-310847-63gh2tg4	147	10	difference	difference	NN
cord-310847-63gh2tg4	147	11	in	in	IN
cord-310847-63gh2tg4	147	12	free	free	JJ
cord-310847-63gh2tg4	147	13	energy	energy	NN
cord-310847-63gh2tg4	147	14	Δ(ΔG	Δ(ΔG	NNP
cord-310847-63gh2tg4	147	15	)	)	-RRB-
cord-310847-63gh2tg4	147	16	estimated	estimate	VBN
cord-310847-63gh2tg4	147	17	in	in	IN
cord-310847-63gh2tg4	147	18	kcal	kcal	NNP
cord-310847-63gh2tg4	147	19	/	/	SYM
cord-310847-63gh2tg4	147	20	mol	mol	NN
cord-310847-63gh2tg4	147	21	per	per	IN
cord-310847-63gh2tg4	147	22	residue	residue	NN
cord-310847-63gh2tg4	147	23	in	in	IN
cord-310847-63gh2tg4	147	24	an	an	DT
cord-310847-63gh2tg4	147	25	α	α	NN
cord-310847-63gh2tg4	147	26	-	-	HYPH
cord-310847-63gh2tg4	147	27	helical	helical	JJ
cord-310847-63gh2tg4	147	28	configuration	configuration	NN
cord-310847-63gh2tg4	147	29	relative	relative	JJ
cord-310847-63gh2tg4	147	30	to	to	IN
cord-310847-63gh2tg4	147	31	alanine	alanine	NN
cord-310847-63gh2tg4	147	32	,	,	,
cord-310847-63gh2tg4	147	33	which	which	WDT
cord-310847-63gh2tg4	147	34	has	have	VBZ
cord-310847-63gh2tg4	147	35	been	be	VBN
cord-310847-63gh2tg4	147	36	set	set	VBN
cord-310847-63gh2tg4	147	37	to	to	IN
cord-310847-63gh2tg4	147	38	zero	zero	CD
cord-310847-63gh2tg4	147	39	because	because	IN
cord-310847-63gh2tg4	147	40	it	-PRON-	PRP
cord-310847-63gh2tg4	147	41	is	be	VBZ
cord-310847-63gh2tg4	147	42	usually	usually	RB
cord-310847-63gh2tg4	147	43	the	the	DT
cord-310847-63gh2tg4	147	44	amino	amino	NN
cord-310847-63gh2tg4	147	45	acid	acid	NN
cord-310847-63gh2tg4	147	46	with	with	IN
cord-310847-63gh2tg4	147	47	the	the	DT
cord-310847-63gh2tg4	147	48	most	most	RBS
cord-310847-63gh2tg4	147	49	favorable	favorable	JJ
cord-310847-63gh2tg4	147	50	helix	helix	NN
cord-310847-63gh2tg4	147	51	propensity	propensity	NN
cord-310847-63gh2tg4	147	52	.	.	.
cord-310847-63gh2tg4	148	1	66	66	CD
cord-310847-63gh2tg4	149	1	Here	here	RB
cord-310847-63gh2tg4	149	2	,	,	,
cord-310847-63gh2tg4	149	3	the	the	DT
cord-310847-63gh2tg4	149	4	higher	high	JJR
cord-310847-63gh2tg4	149	5	helical	helical	JJ
cord-310847-63gh2tg4	149	6	propensity	propensity	NN
cord-310847-63gh2tg4	149	7	values	value	NNS
cord-310847-63gh2tg4	149	8	correspond	correspond	VBP
cord-310847-63gh2tg4	149	9	to	to	IN
cord-310847-63gh2tg4	149	10	more	more	RBR
cord-310847-63gh2tg4	149	11	positive	positive	JJ
cord-310847-63gh2tg4	149	12	free	free	JJ
cord-310847-63gh2tg4	149	13	energies	energy	NNS
cord-310847-63gh2tg4	149	14	and	and	CC
cord-310847-63gh2tg4	149	15	therefore	therefore	RB
cord-310847-63gh2tg4	149	16	are	be	VBP
cord-310847-63gh2tg4	149	17	related	relate	VBN
cord-310847-63gh2tg4	149	18	to	to	IN
cord-310847-63gh2tg4	149	19	residues	residue	NNS
cord-310847-63gh2tg4	149	20	which	which	WDT
cord-310847-63gh2tg4	149	21	are	be	VBP
cord-310847-63gh2tg4	149	22	less	less	RBR
cord-310847-63gh2tg4	149	23	favored	favor	VBN
cord-310847-63gh2tg4	149	24	in	in	IN
cord-310847-63gh2tg4	149	25	α	α	NN
cord-310847-63gh2tg4	149	26	-	-	HYPH
cord-310847-63gh2tg4	149	27	helix	helix	NN
cord-310847-63gh2tg4	149	28	.	.	.
cord-310847-63gh2tg4	150	1	Glutamic	glutamic	NN
cord-310847-63gh2tg4	150	2	acid	acid	NN
cord-310847-63gh2tg4	150	3	in	in	IN
cord-310847-63gh2tg4	150	4	α	α	NN
cord-310847-63gh2tg4	150	5	-	-	HYPH
cord-310847-63gh2tg4	150	6	helix	helix	NN
cord-310847-63gh2tg4	150	7	caps	cap	NNS
cord-310847-63gh2tg4	150	8	.	.	.
cord-310847-63gh2tg4	151	1	Since	since	IN
cord-310847-63gh2tg4	151	2	α	α	NN
cord-310847-63gh2tg4	151	3	-	-	HYPH
cord-310847-63gh2tg4	151	4	helices	helix	NNS
cord-310847-63gh2tg4	151	5	in	in	IN
cord-310847-63gh2tg4	151	6	peptides	peptide	NNS
cord-310847-63gh2tg4	151	7	and	and	CC
cord-310847-63gh2tg4	151	8	proteins	protein	NNS
cord-310847-63gh2tg4	151	9	have	have	VBP
cord-310847-63gh2tg4	151	10	an	an	DT
cord-310847-63gh2tg4	151	11	overall	overall	JJ
cord-310847-63gh2tg4	151	12	dipole	dipole	NN
cord-310847-63gh2tg4	151	13	moments	moment	NNS
cord-310847-63gh2tg4	151	14	caused	cause	VBN
cord-310847-63gh2tg4	151	15	by	by	IN
cord-310847-63gh2tg4	151	16	the	the	DT
cord-310847-63gh2tg4	151	17	cumulative	cumulative	JJ
cord-310847-63gh2tg4	151	18	effects	effect	NNS
cord-310847-63gh2tg4	151	19	of	of	IN
cord-310847-63gh2tg4	151	20	all	all	PDT
cord-310847-63gh2tg4	151	21	the	the	DT
cord-310847-63gh2tg4	151	22	individual	individual	JJ
cord-310847-63gh2tg4	151	23	dipoles	dipole	NNS
cord-310847-63gh2tg4	151	24	from	from	IN
cord-310847-63gh2tg4	151	25	the	the	DT
cord-310847-63gh2tg4	151	26	carbonyl	carbonyl	NN
cord-310847-63gh2tg4	151	27	groups	group	NNS
cord-310847-63gh2tg4	151	28	of	of	IN
cord-310847-63gh2tg4	151	29	the	the	DT
cord-310847-63gh2tg4	151	30	peptide	peptide	NN
cord-310847-63gh2tg4	151	31	bond	bond	NN
cord-310847-63gh2tg4	151	32	pointing	point	VBG
cord-310847-63gh2tg4	151	33	along	along	IN
cord-310847-63gh2tg4	151	34	the	the	DT
cord-310847-63gh2tg4	151	35	helix	helix	NN
cord-310847-63gh2tg4	151	36	axis	axis	NN
cord-310847-63gh2tg4	151	37	,	,	,
cord-310847-63gh2tg4	151	38	the	the	DT
cord-310847-63gh2tg4	151	39	overall	overall	JJ
cord-310847-63gh2tg4	151	40	helical	helical	JJ
cord-310847-63gh2tg4	151	41	structure	structure	NN
cord-310847-63gh2tg4	151	42	is	be	VBZ
cord-310847-63gh2tg4	151	43	destabilized	destabilize	VBN
cord-310847-63gh2tg4	151	44	due	due	IN
cord-310847-63gh2tg4	151	45	to	to	IN
cord-310847-63gh2tg4	151	46	the	the	DT
cord-310847-63gh2tg4	151	47	noticeable	noticeable	JJ
cord-310847-63gh2tg4	151	48	entropic	entropic	JJ
cord-310847-63gh2tg4	151	49	effects	effect	NNS
cord-310847-63gh2tg4	151	50	.	.	.
cord-310847-63gh2tg4	152	1	The	the	DT
cord-310847-63gh2tg4	152	2	effect	effect	NN
cord-310847-63gh2tg4	152	3	of	of	IN
cord-310847-63gh2tg4	152	4	this	this	DT
cord-310847-63gh2tg4	152	5	helical	helical	JJ
cord-310847-63gh2tg4	152	6	dipole	dipole	NN
cord-310847-63gh2tg4	152	7	moment	moment	NN
cord-310847-63gh2tg4	152	8	can	can	MD
cord-310847-63gh2tg4	152	9	be	be	VB
cord-310847-63gh2tg4	152	10	approximated	approximate	VBN
cord-310847-63gh2tg4	152	11	by	by	IN
cord-310847-63gh2tg4	152	12	placing	place	VBG
cord-310847-63gh2tg4	152	13	0.5	0.5	CD
cord-310847-63gh2tg4	152	14	-	-	HYPH
cord-310847-63gh2tg4	152	15	0.7	0.7	CD
cord-310847-63gh2tg4	152	16	positive	positive	JJ
cord-310847-63gh2tg4	152	17	unit	unit	NN
cord-310847-63gh2tg4	152	18	charge	charge	NN
cord-310847-63gh2tg4	152	19	near	near	IN
cord-310847-63gh2tg4	152	20	the	the	DT
cord-310847-63gh2tg4	152	21	N	N	NNP
cord-310847-63gh2tg4	152	22	-	-	HYPH
cord-310847-63gh2tg4	152	23	terminus	terminus	NN
cord-310847-63gh2tg4	152	24	and	and	CC
cord-310847-63gh2tg4	152	25	0.5	0.5	CD
cord-310847-63gh2tg4	152	26	-	-	HYPH
cord-310847-63gh2tg4	152	27	0.7	0.7	CD
cord-310847-63gh2tg4	152	28	negative	negative	JJ
cord-310847-63gh2tg4	152	29	unit	unit	NN
cord-310847-63gh2tg4	152	30	charge	charge	NN
cord-310847-63gh2tg4	152	31	near	near	IN
cord-310847-63gh2tg4	152	32	the	the	DT
cord-310847-63gh2tg4	152	33	C	c	NN
cord-310847-63gh2tg4	152	34	-	-	HYPH
cord-310847-63gh2tg4	152	35	terminus	terminus	NN
cord-310847-63gh2tg4	152	36	of	of	IN
cord-310847-63gh2tg4	152	37	the	the	DT
cord-310847-63gh2tg4	152	38	helix	helix	NN
cord-310847-63gh2tg4	152	39	.	.	.
cord-310847-63gh2tg4	153	1	67	67	CD
cord-310847-63gh2tg4	154	1	,	,	,
cord-310847-63gh2tg4	154	2	68	68	CD
cord-310847-63gh2tg4	154	3	One	one	CD
cord-310847-63gh2tg4	154	4	of	of	IN
cord-310847-63gh2tg4	154	5	the	the	DT
cord-310847-63gh2tg4	154	6	Nature	Nature	NNP
cord-310847-63gh2tg4	154	7	's	's	POS
cord-310847-63gh2tg4	154	8	strategies	strategy	NNS
cord-310847-63gh2tg4	154	9	to	to	TO
cord-310847-63gh2tg4	154	10	neutralize	neutralize	VB
cord-310847-63gh2tg4	154	11	this	this	DT
cord-310847-63gh2tg4	154	12	helix	helix	NN
cord-310847-63gh2tg4	154	13	dipole	dipole	NN
cord-310847-63gh2tg4	154	14	is	be	VBZ
cord-310847-63gh2tg4	154	15	the	the	DT
cord-310847-63gh2tg4	154	16	specific	specific	JJ
cord-310847-63gh2tg4	154	17	capping	capping	NN
cord-310847-63gh2tg4	154	18	of	of	IN
cord-310847-63gh2tg4	154	19	the	the	DT
cord-310847-63gh2tg4	154	20	N	n	CD
cord-310847-63gh2tg4	154	21	-	-	HYPH
cord-310847-63gh2tg4	154	22	terminal	terminal	NN
cord-310847-63gh2tg4	154	23	ends	end	NNS
cord-310847-63gh2tg4	154	24	of	of	IN
cord-310847-63gh2tg4	154	25	α	α	NN
cord-310847-63gh2tg4	154	26	-	-	HYPH
cord-310847-63gh2tg4	154	27	helices	helix	NNS
cord-310847-63gh2tg4	154	28	by	by	IN
cord-310847-63gh2tg4	154	29	negatively	negatively	RB
cord-310847-63gh2tg4	154	30	charged	charge	VBN
cord-310847-63gh2tg4	154	31	residues	residue	NNS
cord-310847-63gh2tg4	154	32	,	,	,
cord-310847-63gh2tg4	154	33	such	such	JJ
cord-310847-63gh2tg4	154	34	as	as	IN
cord-310847-63gh2tg4	154	35	glutamic	glutamic	NN
cord-310847-63gh2tg4	154	36	acids	acid	NNS
cord-310847-63gh2tg4	154	37	.	.	.
cord-310847-63gh2tg4	155	1	67	67	CD
cord-310847-63gh2tg4	156	1	,	,	,
cord-310847-63gh2tg4	156	2	68	68	CD
cord-310847-63gh2tg4	157	1	Furthermore	furthermore	RB
cord-310847-63gh2tg4	157	2	,	,	,
cord-310847-63gh2tg4	157	3	careful	careful	JJ
cord-310847-63gh2tg4	157	4	analysis	analysis	NN
cord-310847-63gh2tg4	157	5	of	of	IN
cord-310847-63gh2tg4	157	6	α	α	NN
cord-310847-63gh2tg4	157	7	-	-	HYPH
cord-310847-63gh2tg4	157	8	helices	helix	NNS
cord-310847-63gh2tg4	157	9	revealed	reveal	VBD
cord-310847-63gh2tg4	157	10	that	that	IN
cord-310847-63gh2tg4	157	11	their	-PRON-	PRP$
cord-310847-63gh2tg4	157	12	first	first	JJ
cord-310847-63gh2tg4	157	13	and	and	CC
cord-310847-63gh2tg4	157	14	last	last	JJ
cord-310847-63gh2tg4	157	15	four	four	CD
cord-310847-63gh2tg4	157	16	residues	residue	NNS
cord-310847-63gh2tg4	157	17	differ	differ	VBP
cord-310847-63gh2tg4	157	18	from	from	IN
cord-310847-63gh2tg4	157	19	the	the	DT
cord-310847-63gh2tg4	157	20	remaining	remain	VBG
cord-310847-63gh2tg4	157	21	residues	residue	NNS
cord-310847-63gh2tg4	157	22	by	by	IN
cord-310847-63gh2tg4	157	23	being	be	VBG
cord-310847-63gh2tg4	157	24	unable	unable	JJ
cord-310847-63gh2tg4	157	25	to	to	TO
cord-310847-63gh2tg4	157	26	make	make	VB
cord-310847-63gh2tg4	157	27	intrα	intrα	NN
cord-310847-63gh2tg4	157	28	-	-	HYPH
cord-310847-63gh2tg4	157	29	helical	helical	JJ
cord-310847-63gh2tg4	157	30	hydrogen	hydrogen	NN
cord-310847-63gh2tg4	157	31	bonds	bond	NNS
cord-310847-63gh2tg4	157	32	.	.	.
cord-310847-63gh2tg4	158	1	Instead	instead	RB
cord-310847-63gh2tg4	158	2	,	,	,
cord-310847-63gh2tg4	158	3	these	these	DT
cord-310847-63gh2tg4	158	4	first	first	JJ
cord-310847-63gh2tg4	158	5	four	four	CD
cord-310847-63gh2tg4	158	6	(	(	-LRB-
cord-310847-63gh2tg4	158	7	>	>	XX
cord-310847-63gh2tg4	158	8	N	n	NN
cord-310847-63gh2tg4	158	9	-	-	HYPH
cord-310847-63gh2tg4	158	10	H	H	NNP
cord-310847-63gh2tg4	158	11	)	)	-RRB-
cord-310847-63gh2tg4	158	12	groups	group	NNS
cord-310847-63gh2tg4	158	13	and	and	CC
cord-310847-63gh2tg4	158	14	last	last	JJ
cord-310847-63gh2tg4	158	15	four	four	CD
cord-310847-63gh2tg4	158	16	(	(	-LRB-
cord-310847-63gh2tg4	158	17	>	>	XX
cord-310847-63gh2tg4	158	18	C	c	NN
cord-310847-63gh2tg4	158	19	=	=	SYM
cord-310847-63gh2tg4	158	20	O	o	NN
cord-310847-63gh2tg4	158	21	)	)	-RRB-
cord-310847-63gh2tg4	158	22	groups	group	NNS
cord-310847-63gh2tg4	158	23	in	in	IN
cord-310847-63gh2tg4	158	24	an	an	DT
cord-310847-63gh2tg4	158	25	α	α	NN
cord-310847-63gh2tg4	158	26	-	-	HYPH
cord-310847-63gh2tg4	158	27	helix	helix	NN
cord-310847-63gh2tg4	158	28	are	be	VBP
cord-310847-63gh2tg4	158	29	often	often	RB
cord-310847-63gh2tg4	158	30	capped	cap	VBN
cord-310847-63gh2tg4	158	31	by	by	IN
cord-310847-63gh2tg4	158	32	alternative	alternative	JJ
cord-310847-63gh2tg4	158	33	hydrogen	hydrogen	NN
cord-310847-63gh2tg4	158	34	bond	bond	NN
cord-310847-63gh2tg4	158	35	partners	partner	NNS
cord-310847-63gh2tg4	158	36	.	.	.
cord-310847-63gh2tg4	159	1	[	[	-LRB-
cord-310847-63gh2tg4	159	2	69	69	CD
cord-310847-63gh2tg4	159	3	]	]	-RRB-
cord-310847-63gh2tg4	159	4	[	[	-LRB-
cord-310847-63gh2tg4	159	5	70	70	CD
cord-310847-63gh2tg4	159	6	]	]	-RRB-
cord-310847-63gh2tg4	159	7	[	[	-LRB-
cord-310847-63gh2tg4	159	8	71	71	CD
cord-310847-63gh2tg4	159	9	]	]	-RRB-
cord-310847-63gh2tg4	159	10	Physico	Physico	NNP
cord-310847-63gh2tg4	159	11	-	-	HYPH
cord-310847-63gh2tg4	159	12	chemical	chemical	NN
cord-310847-63gh2tg4	159	13	and	and	CC
cord-310847-63gh2tg4	159	14	statistical	statistical	JJ
cord-310847-63gh2tg4	159	15	analysis	analysis	NN
cord-310847-63gh2tg4	159	16	suggested	suggest	VBD
cord-310847-63gh2tg4	159	17	that	that	IN
cord-310847-63gh2tg4	159	18	certain	certain	JJ
cord-310847-63gh2tg4	159	19	residues	residue	NNS
cord-310847-63gh2tg4	159	20	are	be	VBP
cord-310847-63gh2tg4	159	21	more	more	RBR
cord-310847-63gh2tg4	159	22	preferable	preferable	JJ
cord-310847-63gh2tg4	159	23	at	at	IN
cord-310847-63gh2tg4	159	24	the	the	DT
cord-310847-63gh2tg4	159	25	C	C	NNP
cord-310847-63gh2tg4	159	26	-	-	HYPH
cord-310847-63gh2tg4	159	27	and	and	CC
cord-310847-63gh2tg4	159	28	N	N	NNP
cord-310847-63gh2tg4	159	29	-	-	HYPH
cord-310847-63gh2tg4	159	30	termini	termini	NNP
cord-310847-63gh2tg4	159	31	of	of	IN
cord-310847-63gh2tg4	159	32	an	an	DT
cord-310847-63gh2tg4	159	33	α	α	NN
cord-310847-63gh2tg4	159	34	-	-	HYPH
cord-310847-63gh2tg4	159	35	helix	helix	NN
cord-310847-63gh2tg4	159	36	(	(	-LRB-
cord-310847-63gh2tg4	159	37	the	the	DT
cord-310847-63gh2tg4	159	38	helical	helical	JJ
cord-310847-63gh2tg4	159	39	C	C	NNP
cord-310847-63gh2tg4	159	40	-	-	HYPH
cord-310847-63gh2tg4	159	41	and	and	CC
cord-310847-63gh2tg4	159	42	N	N	NNP
cord-310847-63gh2tg4	159	43	-	-	HYPH
cord-310847-63gh2tg4	159	44	caps	cap	NNS
cord-310847-63gh2tg4	159	45	)	)	-RRB-
cord-310847-63gh2tg4	159	46	.	.	.
cord-310847-63gh2tg4	160	1	70	70	CD
cord-310847-63gh2tg4	161	1	For	for	IN
cord-310847-63gh2tg4	161	2	example	example	NN
cord-310847-63gh2tg4	161	3	,	,	,
cord-310847-63gh2tg4	161	4	based	base	VBN
cord-310847-63gh2tg4	161	5	on	on	IN
cord-310847-63gh2tg4	161	6	the	the	DT
cord-310847-63gh2tg4	161	7	analysis	analysis	NN
cord-310847-63gh2tg4	161	8	of	of	IN
cord-310847-63gh2tg4	161	9	series	series	NN
cord-310847-63gh2tg4	161	10	of	of	IN
cord-310847-63gh2tg4	161	11	mutations	mutation	NNS
cord-310847-63gh2tg4	161	12	in	in	IN
cord-310847-63gh2tg4	161	13	the	the	DT
cord-310847-63gh2tg4	161	14	two	two	CD
cord-310847-63gh2tg4	161	15	N	n	NN
cord-310847-63gh2tg4	161	16	-	-	HYPH
cord-310847-63gh2tg4	161	17	caps	cap	NNS
cord-310847-63gh2tg4	161	18	of	of	IN
cord-310847-63gh2tg4	161	19	barnase	barnase	NNP
cord-310847-63gh2tg4	161	20	,	,	,
cord-310847-63gh2tg4	161	21	it	-PRON-	PRP
cord-310847-63gh2tg4	161	22	was	be	VBD
cord-310847-63gh2tg4	161	23	concluded	conclude	VBN
cord-310847-63gh2tg4	161	24	that	that	IN
cord-310847-63gh2tg4	161	25	a	a	DT
cord-310847-63gh2tg4	161	26	single	single	JJ
cord-310847-63gh2tg4	161	27	N	n	CD
cord-310847-63gh2tg4	161	28	-	-	HYPH
cord-310847-63gh2tg4	161	29	cap	cap	NN
cord-310847-63gh2tg4	161	30	can	can	MD
cord-310847-63gh2tg4	161	31	stabilize	stabilize	VB
cord-310847-63gh2tg4	161	32	the	the	DT
cord-310847-63gh2tg4	161	33	protein	protein	NN
cord-310847-63gh2tg4	161	34	by	by	IN
cord-310847-63gh2tg4	161	35	up	up	IN
cord-310847-63gh2tg4	161	36	to	to	IN
cord-310847-63gh2tg4	161	37	~2.5	~2.5	CD
cord-310847-63gh2tg4	161	38	kcal	kcal	NNP
cord-310847-63gh2tg4	161	39	/	/	SYM
cord-310847-63gh2tg4	161	40	mol	mol	NN
cord-310847-63gh2tg4	161	41	.	.	.
cord-310847-63gh2tg4	162	1	70	70	CD
cord-310847-63gh2tg4	163	1	Importantly	importantly	RB
cord-310847-63gh2tg4	163	2	,	,	,
cord-310847-63gh2tg4	163	3	the	the	DT
cord-310847-63gh2tg4	163	4	presence	presence	NN
cord-310847-63gh2tg4	163	5	of	of	IN
cord-310847-63gh2tg4	163	6	a	a	DT
cord-310847-63gh2tg4	163	7	negative	negative	JJ
cord-310847-63gh2tg4	163	8	charge	charge	NN
cord-310847-63gh2tg4	163	9	of	of	IN
cord-310847-63gh2tg4	163	10	the	the	DT
cord-310847-63gh2tg4	163	11	N	N	NNP
cord-310847-63gh2tg4	163	12	-	-	HYPH
cord-310847-63gh2tg4	163	13	cap	cap	NN
cord-310847-63gh2tg4	163	14	was	be	VBD
cord-310847-63gh2tg4	163	15	shown	show	VBN
cord-310847-63gh2tg4	163	16	to	to	TO
cord-310847-63gh2tg4	163	17	add	add	VB
cord-310847-63gh2tg4	163	18	~1.6	~1.6	NFP
cord-310847-63gh2tg4	163	19	kcal	kcal	NNP
cord-310847-63gh2tg4	163	20	/	/	SYM
cord-310847-63gh2tg4	163	21	mol	mol	NN
cord-310847-63gh2tg4	163	22	of	of	IN
cord-310847-63gh2tg4	163	23	stabilization	stabilization	NN
cord-310847-63gh2tg4	163	24	energy	energy	NN
cord-310847-63gh2tg4	163	25	mostly	mostly	RB
cord-310847-63gh2tg4	163	26	due	due	JJ
cord-310847-63gh2tg4	163	27	to	to	IN
cord-310847-63gh2tg4	163	28	the	the	DT
cord-310847-63gh2tg4	163	29	compensation	compensation	NN
cord-310847-63gh2tg4	163	30	effects	effect	NNS
cord-310847-63gh2tg4	163	31	for	for	IN
cord-310847-63gh2tg4	163	32	the	the	DT
cord-310847-63gh2tg4	163	33	macroscopic	macroscopic	JJ
cord-310847-63gh2tg4	163	34	electrostatic	electrostatic	JJ
cord-310847-63gh2tg4	163	35	dipole	dipole	NN
cord-310847-63gh2tg4	163	36	of	of	IN
cord-310847-63gh2tg4	163	37	the	the	DT
cord-310847-63gh2tg4	163	38	helix	helix	NN
cord-310847-63gh2tg4	163	39	.	.	.
cord-310847-63gh2tg4	164	1	70	70	CD
cord-310847-63gh2tg4	165	1	From	from	IN
cord-310847-63gh2tg4	165	2	a	a	DT
cord-310847-63gh2tg4	165	3	global	global	JJ
cord-310847-63gh2tg4	165	4	survey	survey	NN
cord-310847-63gh2tg4	165	5	among	among	IN
cord-310847-63gh2tg4	165	6	proteins	protein	NNS
cord-310847-63gh2tg4	165	7	of	of	IN
cord-310847-63gh2tg4	165	8	known	know	VBN
cord-310847-63gh2tg4	165	9	structure	structure	NN
cord-310847-63gh2tg4	165	10	,	,	,
cord-310847-63gh2tg4	165	11	seven	seven	CD
cord-310847-63gh2tg4	165	12	distinct	distinct	JJ
cord-310847-63gh2tg4	165	13	capping	cap	VBG
cord-310847-63gh2tg4	165	14	motifs	motif	NNS
cord-310847-63gh2tg4	165	15	are	be	VBP
cord-310847-63gh2tg4	165	16	identified	identify	VBN
cord-310847-63gh2tg4	165	17	-	-	HYPH
cord-310847-63gh2tg4	165	18	three	three	CD
cord-310847-63gh2tg4	165	19	at	at	IN
cord-310847-63gh2tg4	165	20	the	the	DT
cord-310847-63gh2tg4	165	21	helix	helix	NN
cord-310847-63gh2tg4	165	22	N	n	CD
cord-310847-63gh2tg4	165	23	-	-	HYPH
cord-310847-63gh2tg4	165	24	terminus	terminus	NN
cord-310847-63gh2tg4	165	25	and	and	CC
cord-310847-63gh2tg4	165	26	four	four	CD
cord-310847-63gh2tg4	165	27	at	at	IN
cord-310847-63gh2tg4	165	28	the	the	DT
cord-310847-63gh2tg4	165	29	C	c	NN
cord-310847-63gh2tg4	165	30	-	-	HYPH
cord-310847-63gh2tg4	165	31	terminus	terminus	NN
cord-310847-63gh2tg4	165	32	.	.	.
cord-310847-63gh2tg4	166	1	71	71	CD
cord-310847-63gh2tg4	166	2	One	one	CD
cord-310847-63gh2tg4	166	3	of	of	IN
cord-310847-63gh2tg4	166	4	these	these	DT
cord-310847-63gh2tg4	166	5	motifs	motif	NNS
cord-310847-63gh2tg4	166	6	is	be	VBZ
cord-310847-63gh2tg4	166	7	the	the	DT
cord-310847-63gh2tg4	166	8	helix	helix	NN
cord-310847-63gh2tg4	166	9	-	-	HYPH
cord-310847-63gh2tg4	166	10	capping	cap	VBG
cord-310847-63gh2tg4	166	11	motif	motif	NN
cord-310847-63gh2tg4	166	12	Ser	Ser	NNP
cord-310847-63gh2tg4	166	13	-	-	HYPH
cord-310847-63gh2tg4	166	14	X	x	NN
cord-310847-63gh2tg4	166	15	-	-	HYPH
cord-310847-63gh2tg4	166	16	X	X	NNP
cord-310847-63gh2tg4	166	17	-	-	HYPH
cord-310847-63gh2tg4	166	18	Glu	Glu	NNP
cord-310847-63gh2tg4	166	19	,	,	,
cord-310847-63gh2tg4	166	20	a	a	DT
cord-310847-63gh2tg4	166	21	sequence	sequence	NN
cord-310847-63gh2tg4	166	22	that	that	WDT
cord-310847-63gh2tg4	166	23	occurs	occur	VBZ
cord-310847-63gh2tg4	166	24	frequently	frequently	RB
cord-310847-63gh2tg4	166	25	at	at	IN
cord-310847-63gh2tg4	166	26	the	the	DT
cord-310847-63gh2tg4	166	27	N	N	NNP
cord-310847-63gh2tg4	166	28	-	-	HYPH
cord-310847-63gh2tg4	166	29	termini	termini	NNP
cord-310847-63gh2tg4	166	30	of	of	IN
cord-310847-63gh2tg4	166	31	α	α	NN
cord-310847-63gh2tg4	166	32	-	-	HYPH
cord-310847-63gh2tg4	166	33	helices	helix	NNS
cord-310847-63gh2tg4	166	34	in	in	IN
cord-310847-63gh2tg4	166	35	proteins	protein	NNS
cord-310847-63gh2tg4	166	36	.	.	.
cord-310847-63gh2tg4	167	1	[	[	-LRB-
cord-310847-63gh2tg4	167	2	71	71	CD
cord-310847-63gh2tg4	167	3	]	]	-RRB-
cord-310847-63gh2tg4	167	4	[	[	-LRB-
cord-310847-63gh2tg4	167	5	72	72	CD
cord-310847-63gh2tg4	167	6	]	]	-RRB-
cord-310847-63gh2tg4	168	1	[	[	-LRB-
cord-310847-63gh2tg4	168	2	73	73	CD
cord-310847-63gh2tg4	168	3	]	]	-RRB-
cord-310847-63gh2tg4	169	1	Thermodynamic	thermodynamic	JJ
cord-310847-63gh2tg4	169	2	analysis	analysis	NN
cord-310847-63gh2tg4	169	3	of	of	IN
cord-310847-63gh2tg4	169	4	this	this	DT
cord-310847-63gh2tg4	169	5	Ser	Ser	NNP
cord-310847-63gh2tg4	169	6	-	-	HYPH
cord-310847-63gh2tg4	169	7	X	x	NN
cord-310847-63gh2tg4	169	8	-	-	HYPH
cord-310847-63gh2tg4	169	9	X	x	NN
cord-310847-63gh2tg4	169	10	-	-	HYPH
cord-310847-63gh2tg4	169	11	Glu	glu	NN
cord-310847-63gh2tg4	169	12	motif	motif	NN
cord-310847-63gh2tg4	169	13	from	from	IN
cord-310847-63gh2tg4	169	14	the	the	DT
cord-310847-63gh2tg4	169	15	ramachandran	ramachandran	NNP
cord-310847-63gh2tg4	169	16	plots	plot	NNS
cord-310847-63gh2tg4	169	17	for	for	IN
cord-310847-63gh2tg4	169	18	backbone	backbone	NN
cord-310847-63gh2tg4	169	19	conformations	conformation	NNS
cord-310847-63gh2tg4	169	20	of	of	IN
cord-310847-63gh2tg4	169	21	the	the	DT
cord-310847-63gh2tg4	169	22	18	18	CD
cord-310847-63gh2tg4	169	23	non	non	JJ
cord-310847-63gh2tg4	169	24	-	-	JJ
cord-310847-63gh2tg4	169	25	glycine	glycine	JJ
cord-310847-63gh2tg4	169	26	and	and	CC
cord-310847-63gh2tg4	169	27	non	non	JJ
cord-310847-63gh2tg4	169	28	-	-	JJ
cord-310847-63gh2tg4	169	29	proline	proline	JJ
cord-310847-63gh2tg4	169	30	amino	amino	NN
cord-310847-63gh2tg4	169	31	acids	acid	NNS
cord-310847-63gh2tg4	169	32	.	.	.
cord-310847-63gh2tg4	170	1	Marked	marked	JJ
cord-310847-63gh2tg4	170	2	regions	region	NNS
cord-310847-63gh2tg4	170	3	of	of	IN
cord-310847-63gh2tg4	170	4	density	density	NN
cord-310847-63gh2tg4	170	5	correspond	correspond	VBP
cord-310847-63gh2tg4	170	6	to	to	IN
cord-310847-63gh2tg4	170	7	the	the	DT
cord-310847-63gh2tg4	170	8	right	right	RB
cord-310847-63gh2tg4	170	9	-	-	HYPH
cord-310847-63gh2tg4	170	10	handed	handed	JJ
cord-310847-63gh2tg4	170	11	α	α	NN
cord-310847-63gh2tg4	170	12	-	-	HYPH
cord-310847-63gh2tg4	170	13	helix	helix	NN
cord-310847-63gh2tg4	170	14	region	region	NN
cord-310847-63gh2tg4	170	15	(	(	-LRB-
cord-310847-63gh2tg4	170	16	α	α	NN
cord-310847-63gh2tg4	170	17	)	)	-RRB-
cord-310847-63gh2tg4	170	18	,	,	,
cord-310847-63gh2tg4	170	19	mirror	mirror	NN
cord-310847-63gh2tg4	170	20	image	image	NN
cord-310847-63gh2tg4	170	21	of	of	IN
cord-310847-63gh2tg4	170	22	α	α	NN
cord-310847-63gh2tg4	170	23	(	(	-LRB-
cord-310847-63gh2tg4	170	24	α	α	NNP
cord-310847-63gh2tg4	170	25	L	L	NNP
cord-310847-63gh2tg4	170	26	)	)	-RRB-
cord-310847-63gh2tg4	170	27	,	,	,
cord-310847-63gh2tg4	170	28	region	region	NN
cord-310847-63gh2tg4	170	29	largely	largely	RB
cord-310847-63gh2tg4	170	30	involved	involve	VBN
cord-310847-63gh2tg4	170	31	in	in	IN
cord-310847-63gh2tg4	170	32	β	β	NN
cord-310847-63gh2tg4	170	33	-	-	HYPH
cord-310847-63gh2tg4	170	34	sheet	sheet	NN
cord-310847-63gh2tg4	170	35	formation	formation	NN
cord-310847-63gh2tg4	170	36	(	(	-LRB-
cord-310847-63gh2tg4	170	37	β	β	NNP
cord-310847-63gh2tg4	170	38	S	S	NNP
cord-310847-63gh2tg4	170	39	)	)	-RRB-
cord-310847-63gh2tg4	170	40	,	,	,
cord-310847-63gh2tg4	170	41	and	and	CC
cord-310847-63gh2tg4	170	42	region	region	NN
cord-310847-63gh2tg4	170	43	associated	associate	VBN
cord-310847-63gh2tg4	170	44	with	with	IN
cord-310847-63gh2tg4	170	45	extended	extended	JJ
cord-310847-63gh2tg4	170	46	polyproline	polyproline	NN
cord-310847-63gh2tg4	170	47	-	-	HYPH
cord-310847-63gh2tg4	170	48	like	like	JJ
cord-310847-63gh2tg4	170	49	helices	helix	NNS
cord-310847-63gh2tg4	170	50	,	,	,
cord-310847-63gh2tg4	170	51	but	but	CC
cord-310847-63gh2tg4	170	52	also	also	RB
cord-310847-63gh2tg4	170	53	observed	observe	VBD
cord-310847-63gh2tg4	170	54	in	in	IN
cord-310847-63gh2tg4	170	55	β	β	NN
cord-310847-63gh2tg4	170	56	-	-	HYPH
cord-310847-63gh2tg4	170	57	sheet	sheet	NN
cord-310847-63gh2tg4	170	58	(	(	-LRB-
cord-310847-63gh2tg4	170	59	β	β	NN
cord-310847-63gh2tg4	170	60	P	p	NN
cord-310847-63gh2tg4	170	61	)	)	-RRB-
cord-310847-63gh2tg4	170	62	.	.	.
cord-310847-63gh2tg4	171	1	by	by	IN
cord-310847-63gh2tg4	171	2	the	the	DT
cord-310847-63gh2tg4	171	3	four	four	CD
cord-310847-63gh2tg4	171	4	glutamic	glutamic	NN
cord-310847-63gh2tg4	171	5	acid	acid	NN
cord-310847-63gh2tg4	171	6	residues	residue	NNS
cord-310847-63gh2tg4	171	7	located	locate	VBN
cord-310847-63gh2tg4	171	8	at	at	IN
cord-310847-63gh2tg4	171	9	homologous	homologous	JJ
cord-310847-63gh2tg4	171	10	positions	position	NNS
cord-310847-63gh2tg4	171	11	within	within	IN
cord-310847-63gh2tg4	171	12	each	each	DT
cord-310847-63gh2tg4	171	13	of	of	IN
cord-310847-63gh2tg4	171	14	the	the	DT
cord-310847-63gh2tg4	171	15	four	four	CD
cord-310847-63gh2tg4	171	16	pore	pore	NN
cord-310847-63gh2tg4	171	17	-	-	HYPH
cord-310847-63gh2tg4	171	18	forming	form	VBG
cord-310847-63gh2tg4	171	19	segments	segment	NNS
cord-310847-63gh2tg4	171	20	and	and	CC
cord-310847-63gh2tg4	171	21	which	which	WDT
cord-310847-63gh2tg4	171	22	form	form	VBP
cord-310847-63gh2tg4	171	23	a	a	DT
cord-310847-63gh2tg4	171	24	single	single	JJ
cord-310847-63gh2tg4	171	25	or	or	CC
cord-310847-63gh2tg4	171	26	multiple	multiple	JJ
cord-310847-63gh2tg4	172	1	Ca	ca	NN
cord-310847-63gh2tg4	172	2	2	2	CD
cord-310847-63gh2tg4	172	3	+	+	CD
cord-310847-63gh2tg4	172	4	-binding	-binding	NNP
cord-310847-63gh2tg4	172	5	site(s	site(s	RB
cord-310847-63gh2tg4	172	6	)	)	-RRB-
cord-310847-63gh2tg4	172	7	that	that	WDT
cord-310847-63gh2tg4	172	8	entrap	entrap	VBP
cord-310847-63gh2tg4	172	9	calcium	calcium	NN
cord-310847-63gh2tg4	172	10	ions	ion	NNS
cord-310847-63gh2tg4	172	11	,	,	,
cord-310847-63gh2tg4	172	12	thus	thus	RB
cord-310847-63gh2tg4	172	13	giving	give	VBG
cord-310847-63gh2tg4	172	14	them	-PRON-	PRP
cord-310847-63gh2tg4	172	15	a	a	DT
cord-310847-63gh2tg4	172	16	possibility	possibility	NN
cord-310847-63gh2tg4	172	17	to	to	TO
cord-310847-63gh2tg4	172	18	be	be	VB
cord-310847-63gh2tg4	172	19	electrostatically	electrostatically	RB
cord-310847-63gh2tg4	172	20	repulsed	repulse	VBN
cord-310847-63gh2tg4	172	21	through	through	IN
cord-310847-63gh2tg4	172	22	the	the	DT
cord-310847-63gh2tg4	172	23	intracellular	intracellular	JJ
cord-310847-63gh2tg4	172	24	opening	opening	NN
cord-310847-63gh2tg4	172	25	of	of	IN
cord-310847-63gh2tg4	172	26	the	the	DT
cord-310847-63gh2tg4	172	27	pore	pore	NN
cord-310847-63gh2tg4	172	28	.	.	.
cord-310847-63gh2tg4	173	1	87	87	CD
cord-310847-63gh2tg4	174	1	In	in	IN
cord-310847-63gh2tg4	174	2	the	the	DT
cord-310847-63gh2tg4	174	3	bacterial	bacterial	JJ
cord-310847-63gh2tg4	174	4	KcsA	KcsA	NNP
cord-310847-63gh2tg4	174	5	and	and	CC
cord-310847-63gh2tg4	174	6	inwardly	inwardly	RB
cord-310847-63gh2tg4	174	7	rectifying	rectify	VBG
cord-310847-63gh2tg4	174	8	K	k	NN
cord-310847-63gh2tg4	174	9	+	+	CC
cord-310847-63gh2tg4	174	10	(	(	-LRB-
cord-310847-63gh2tg4	174	11	Kir	Kir	NNP
cord-310847-63gh2tg4	174	12	)	)	-RRB-
cord-310847-63gh2tg4	174	13	channels	channel	NNS
cord-310847-63gh2tg4	174	14	,	,	,
cord-310847-63gh2tg4	174	15	glutamic	glutamic	NN
cord-310847-63gh2tg4	174	16	acid	acid	NN
cord-310847-63gh2tg4	174	17	is	be	VBZ
cord-310847-63gh2tg4	174	18	also	also	RB
cord-310847-63gh2tg4	174	19	involved	involve	VBN
cord-310847-63gh2tg4	174	20	in	in	IN
cord-310847-63gh2tg4	174	21	the	the	DT
cord-310847-63gh2tg4	174	22	action	action	NN
cord-310847-63gh2tg4	174	23	of	of	IN
cord-310847-63gh2tg4	174	24	the	the	DT
cord-310847-63gh2tg4	174	25	selectivity	selectivity	NN
cord-310847-63gh2tg4	174	26	filter	filter	NN
cord-310847-63gh2tg4	174	27	.	.	.
cord-310847-63gh2tg4	175	1	88	88	CD
cord-310847-63gh2tg4	176	1	Here	here	RB
cord-310847-63gh2tg4	176	2	,	,	,
cord-310847-63gh2tg4	176	3	the	the	DT
cord-310847-63gh2tg4	176	4	network	network	NN
cord-310847-63gh2tg4	176	5	of	of	IN
cord-310847-63gh2tg4	176	6	residues	residue	NNS
cord-310847-63gh2tg4	176	7	stabilizing	stabilize	VBG
cord-310847-63gh2tg4	176	8	the	the	DT
cord-310847-63gh2tg4	176	9	pore	pore	NN
cord-310847-63gh2tg4	176	10	of	of	IN
cord-310847-63gh2tg4	176	11	KcsA	KcsA	NNP
cord-310847-63gh2tg4	176	12	involves	involve	VBZ
cord-310847-63gh2tg4	176	13	a	a	DT
cord-310847-63gh2tg4	176	14	Glu71-Asp80	Glu71-Asp80	NNP
cord-310847-63gh2tg4	176	15	carboxyl	carboxyl	NN
cord-310847-63gh2tg4	176	16	-	-	HYPH
cord-310847-63gh2tg4	176	17	carboxylate	carboxylate	VBG
cord-310847-63gh2tg4	176	18	interaction	interaction	NN
cord-310847-63gh2tg4	176	19	behind	behind	IN
cord-310847-63gh2tg4	176	20	the	the	DT
cord-310847-63gh2tg4	176	21	selectivity	selectivity	NN
cord-310847-63gh2tg4	176	22	filter	filter	NN
cord-310847-63gh2tg4	176	23	,	,	,
cord-310847-63gh2tg4	176	24	whereas	whereas	IN
cord-310847-63gh2tg4	176	25	the	the	DT
cord-310847-63gh2tg4	176	26	structure	structure	NN
cord-310847-63gh2tg4	176	27	of	of	IN
cord-310847-63gh2tg4	176	28	the	the	DT
cord-310847-63gh2tg4	176	29	pore	pore	NN
cord-310847-63gh2tg4	176	30	in	in	IN
cord-310847-63gh2tg4	176	31	Kir	Kir	NNP
cord-310847-63gh2tg4	176	32	channels	channel	NNS
cord-310847-63gh2tg4	176	33	is	be	VBZ
cord-310847-63gh2tg4	176	34	stabilized	stabilize	VBN
cord-310847-63gh2tg4	176	35	by	by	IN
cord-310847-63gh2tg4	176	36	a	a	DT
cord-310847-63gh2tg4	176	37	Glu	Glu	NNP
cord-310847-63gh2tg4	176	38	-	-	HYPH
cord-310847-63gh2tg4	176	39	Arg	Arg	NNP
cord-310847-63gh2tg4	176	40	salt	salt	NN
cord-310847-63gh2tg4	176	41	bridge	bridge	NN
cord-310847-63gh2tg4	176	42	.	.	.
cord-310847-63gh2tg4	177	1	88	88	CD
cord-310847-63gh2tg4	178	1	Therefore	therefore	RB
cord-310847-63gh2tg4	178	2	,	,	,
cord-310847-63gh2tg4	178	3	although	although	IN
cord-310847-63gh2tg4	178	4	Glu	Glu	NNP
cord-310847-63gh2tg4	178	5	is	be	VBZ
cord-310847-63gh2tg4	178	6	quite	quite	RB
cord-310847-63gh2tg4	178	7	conserved	conserved	JJ
cord-310847-63gh2tg4	178	8	among	among	IN
cord-310847-63gh2tg4	178	9	both	both	DT
cord-310847-63gh2tg4	178	10	types	type	NNS
cord-310847-63gh2tg4	178	11	of	of	IN
cord-310847-63gh2tg4	178	12	channels	channel	NNS
cord-310847-63gh2tg4	178	13	,	,	,
cord-310847-63gh2tg4	178	14	the	the	DT
cord-310847-63gh2tg4	178	15	network	network	NN
cord-310847-63gh2tg4	178	16	of	of	IN
cord-310847-63gh2tg4	178	17	interactions	interaction	NNS
cord-310847-63gh2tg4	178	18	is	be	VBZ
cord-310847-63gh2tg4	178	19	not	not	RB
cord-310847-63gh2tg4	178	20	translatable	translatable	JJ
cord-310847-63gh2tg4	178	21	from	from	IN
cord-310847-63gh2tg4	178	22	one	one	CD
cord-310847-63gh2tg4	178	23	channel	channel	NN
cord-310847-63gh2tg4	178	24	to	to	IN
cord-310847-63gh2tg4	178	25	the	the	DT
cord-310847-63gh2tg4	178	26	other	other	JJ
cord-310847-63gh2tg4	178	27	.	.	.
cord-310847-63gh2tg4	179	1	This	this	DT
cord-310847-63gh2tg4	179	2	clearly	clearly	RB
cord-310847-63gh2tg4	179	3	shows	show	VBZ
cord-310847-63gh2tg4	179	4	that	that	IN
cord-310847-63gh2tg4	179	5	different	different	JJ
cord-310847-63gh2tg4	179	6	potassium	potassium	NN
cord-310847-63gh2tg4	179	7	channels	channel	NNS
cord-310847-63gh2tg4	179	8	are	be	VBP
cord-310847-63gh2tg4	179	9	characterized	characterize	VBN
cord-310847-63gh2tg4	179	10	by	by	IN
cord-310847-63gh2tg4	179	11	diverse	diverse	JJ
cord-310847-63gh2tg4	179	12	gating	gating	NN
cord-310847-63gh2tg4	179	13	patterns	pattern	NNS
cord-310847-63gh2tg4	179	14	.	.	.
cord-310847-63gh2tg4	180	1	88	88	CD
cord-310847-63gh2tg4	181	1	The	the	DT
cord-310847-63gh2tg4	181	2	presence	presence	NN
cord-310847-63gh2tg4	181	3	of	of	IN
cord-310847-63gh2tg4	181	4	a	a	DT
cord-310847-63gh2tg4	181	5	highly	highly	RB
cord-310847-63gh2tg4	181	6	conserved	conserved	JJ
cord-310847-63gh2tg4	181	7	glutamic	glutamic	NN
cord-310847-63gh2tg4	181	8	acid	acid	NN
cord-310847-63gh2tg4	181	9	residue	residue	NN
cord-310847-63gh2tg4	181	10	in	in	IN
cord-310847-63gh2tg4	181	11	the	the	DT
cord-310847-63gh2tg4	181	12	middle	middle	NN
cord-310847-63gh2tg4	181	13	of	of	IN
cord-310847-63gh2tg4	181	14	a	a	DT
cord-310847-63gh2tg4	181	15	transmembrane	transmembrane	NN
cord-310847-63gh2tg4	181	16	domain	domain	NN
cord-310847-63gh2tg4	181	17	is	be	VBZ
cord-310847-63gh2tg4	181	18	a	a	DT
cord-310847-63gh2tg4	181	19	characteristic	characteristic	JJ
cord-310847-63gh2tg4	181	20	feature	feature	NN
cord-310847-63gh2tg4	181	21	of	of	IN
cord-310847-63gh2tg4	181	22	a	a	DT
cord-310847-63gh2tg4	181	23	family	family	NN
cord-310847-63gh2tg4	181	24	of	of	IN
cord-310847-63gh2tg4	181	25	transmembrane	transmembrane	JJ
cord-310847-63gh2tg4	181	26	glycoproteins	glycoprotein	NNS
cord-310847-63gh2tg4	181	27	with	with	IN
cord-310847-63gh2tg4	181	28	two	two	CD
cord-310847-63gh2tg4	181	29	immunoglobulin	immunoglobulin	NN
cord-310847-63gh2tg4	181	30	-	-	HYPH
cord-310847-63gh2tg4	181	31	like	like	JJ
cord-310847-63gh2tg4	181	32	domains	domain	NNS
cord-310847-63gh2tg4	181	33	,	,	,
cord-310847-63gh2tg4	181	34	such	such	JJ
cord-310847-63gh2tg4	181	35	as	as	IN
cord-310847-63gh2tg4	181	36	basigin	basigin	NNP
cord-310847-63gh2tg4	181	37	(	(	-LRB-
cord-310847-63gh2tg4	181	38	Bsg	Bsg	NNP
cord-310847-63gh2tg4	181	39	,	,	,
cord-310847-63gh2tg4	181	40	also	also	RB
cord-310847-63gh2tg4	181	41	known	know	VBN
cord-310847-63gh2tg4	181	42	as	as	IN
cord-310847-63gh2tg4	181	43	CD147	CD147	NNP
cord-310847-63gh2tg4	181	44	or	or	CC
cord-310847-63gh2tg4	181	45	EMMPRIN	EMMPRIN	NNP
cord-310847-63gh2tg4	181	46	)	)	-RRB-
cord-310847-63gh2tg4	181	47	,	,	,
cord-310847-63gh2tg4	181	48	embigin	embigin	NNP
cord-310847-63gh2tg4	181	49	and	and	CC
cord-310847-63gh2tg4	181	50	neuroplastin	neuroplastin	NNP
cord-310847-63gh2tg4	181	51	.	.	.
cord-310847-63gh2tg4	182	1	89	89	CD
cord-310847-63gh2tg4	183	1	Finally	finally	RB
cord-310847-63gh2tg4	183	2	,	,	,
cord-310847-63gh2tg4	183	3	a	a	DT
cord-310847-63gh2tg4	183	4	critical	critical	JJ
cord-310847-63gh2tg4	183	5	glutamic	glutamic	NN
cord-310847-63gh2tg4	183	6	acid	acid	NN
cord-310847-63gh2tg4	183	7	residue	residue	NN
cord-310847-63gh2tg4	183	8	was	be	VBD
cord-310847-63gh2tg4	183	9	recently	recently	RB
cord-310847-63gh2tg4	183	10	identified	identify	VBN
cord-310847-63gh2tg4	183	11	in	in	IN
cord-310847-63gh2tg4	183	12	CLC	CLC	NNP
cord-310847-63gh2tg4	183	13	proteins	protein	NNS
cord-310847-63gh2tg4	183	14	,	,	,
cord-310847-63gh2tg4	183	15	which	which	WDT
cord-310847-63gh2tg4	183	16	constitute	constitute	VBP
cord-310847-63gh2tg4	183	17	a	a	DT
cord-310847-63gh2tg4	183	18	large	large	JJ
cord-310847-63gh2tg4	183	19	structurally	structurally	RB
cord-310847-63gh2tg4	183	20	defined	define	VBN
cord-310847-63gh2tg4	183	21	family	family	NN
cord-310847-63gh2tg4	183	22	of	of	IN
cord-310847-63gh2tg4	183	23	Cl	Cl	NNP
cord-310847-63gh2tg4	183	24	−	−	NNP
cord-310847-63gh2tg4	183	25	ion	ion	NN
cord-310847-63gh2tg4	183	26	channels	channel	NNS
cord-310847-63gh2tg4	183	27	and	and	CC
cord-310847-63gh2tg4	183	28	H	h	NN
cord-310847-63gh2tg4	183	29	+	+	CC
cord-310847-63gh2tg4	183	30	/Cl	/cl	NN
cord-310847-63gh2tg4	183	31	−	−	NNP
cord-310847-63gh2tg4	183	32	antiporters	antiporter	NNS
cord-310847-63gh2tg4	183	33	which	which	WDT
cord-310847-63gh2tg4	183	34	are	be	VBP
cord-310847-63gh2tg4	183	35	found	find	VBN
cord-310847-63gh2tg4	183	36	in	in	IN
cord-310847-63gh2tg4	183	37	prokaryotes	prokaryote	NNS
cord-310847-63gh2tg4	183	38	and	and	CC
cord-310847-63gh2tg4	183	39	eukaryotes	eukaryote	NNS
cord-310847-63gh2tg4	183	40	,	,	,
cord-310847-63gh2tg4	183	41	90	90	CD
cord-310847-63gh2tg4	183	42	and	and	CC
cord-310847-63gh2tg4	183	43	which	which	WDT
cord-310847-63gh2tg4	183	44	perform	perform	VBP
cord-310847-63gh2tg4	183	45	their	-PRON-	PRP$
cord-310847-63gh2tg4	183	46	functions	function	NNS
cord-310847-63gh2tg4	183	47	in	in	IN
cord-310847-63gh2tg4	183	48	the	the	DT
cord-310847-63gh2tg4	183	49	plasma	plasma	NN
cord-310847-63gh2tg4	183	50	membrane	membrane	NN
cord-310847-63gh2tg4	183	51	or	or	CC
cord-310847-63gh2tg4	183	52	in	in	IN
cord-310847-63gh2tg4	183	53	various	various	JJ
cord-310847-63gh2tg4	183	54	intracellular	intracellular	JJ
cord-310847-63gh2tg4	183	55	organelles	organelle	NNS
cord-310847-63gh2tg4	183	56	such	such	JJ
cord-310847-63gh2tg4	183	57	as	as	IN
cord-310847-63gh2tg4	183	58	vesicles	vesicle	NNS
cord-310847-63gh2tg4	183	59	of	of	IN
cord-310847-63gh2tg4	183	60	the	the	DT
cord-310847-63gh2tg4	183	61	endosomal	endosomal	NNP
cord-310847-63gh2tg4	183	62	/	/	SYM
cord-310847-63gh2tg4	183	63	lysosomal	lysosomal	JJ
cord-310847-63gh2tg4	183	64	pathway	pathway	NN
cord-310847-63gh2tg4	183	65	or	or	CC
cord-310847-63gh2tg4	183	66	in	in	IN
cord-310847-63gh2tg4	183	67	synaptic	synaptic	JJ
cord-310847-63gh2tg4	183	68	vesicles	vesicle	NNS
cord-310847-63gh2tg4	183	69	.	.	.
cord-310847-63gh2tg4	184	1	91	91	CD
cord-310847-63gh2tg4	184	2	Mutations	mutation	NNS
cord-310847-63gh2tg4	184	3	in	in	IN
cord-310847-63gh2tg4	184	4	human	human	JJ
cord-310847-63gh2tg4	184	5	CLC	CLC	NNP
cord-310847-63gh2tg4	184	6	channels	channel	NNS
cord-310847-63gh2tg4	184	7	are	be	VBP
cord-310847-63gh2tg4	184	8	known	know	VBN
cord-310847-63gh2tg4	184	9	to	to	TO
cord-310847-63gh2tg4	184	10	cause	cause	VB
cord-310847-63gh2tg4	184	11	a	a	DT
cord-310847-63gh2tg4	184	12	set	set	NN
cord-310847-63gh2tg4	184	13	of	of	IN
cord-310847-63gh2tg4	184	14	very	very	RB
cord-310847-63gh2tg4	184	15	diverse	diverse	JJ
cord-310847-63gh2tg4	184	16	diseases	disease	NNS
cord-310847-63gh2tg4	184	17	such	such	JJ
cord-310847-63gh2tg4	184	18	as	as	IN
cord-310847-63gh2tg4	184	19	myotonia	myotonia	NN
cord-310847-63gh2tg4	184	20	(	(	-LRB-
cord-310847-63gh2tg4	184	21	muscle	muscle	NN
cord-310847-63gh2tg4	184	22	stiffness	stiffness	NN
cord-310847-63gh2tg4	184	23	)	)	-RRB-
cord-310847-63gh2tg4	184	24	,	,	,
cord-310847-63gh2tg4	184	25	Bartter	Bartter	NNP
cord-310847-63gh2tg4	184	26	syndrome	syndrome	NN
cord-310847-63gh2tg4	184	27	(	(	-LRB-
cord-310847-63gh2tg4	184	28	renal	renal	JJ
cord-310847-63gh2tg4	184	29	salt	salt	NN
cord-310847-63gh2tg4	184	30	loss	loss	NN
cord-310847-63gh2tg4	184	31	)	)	-RRB-
cord-310847-63gh2tg4	184	32	with	with	IN
cord-310847-63gh2tg4	184	33	or	or	CC
cord-310847-63gh2tg4	184	34	without	without	IN
cord-310847-63gh2tg4	184	35	deafness	deafness	NN
cord-310847-63gh2tg4	184	36	,	,	,
cord-310847-63gh2tg4	184	37	Dent	Dent	NNP
cord-310847-63gh2tg4	184	38	's	's	POS
cord-310847-63gh2tg4	184	39	disease	disease	NN
cord-310847-63gh2tg4	184	40	(	(	-LRB-
cord-310847-63gh2tg4	184	41	proteinuria	proteinuria	NN
cord-310847-63gh2tg4	184	42	and	and	CC
cord-310847-63gh2tg4	184	43	kidney	kidney	NN
cord-310847-63gh2tg4	184	44	stones	stone	NNS
cord-310847-63gh2tg4	184	45	)	)	-RRB-
cord-310847-63gh2tg4	184	46	,	,	,
cord-310847-63gh2tg4	184	47	osteopetrosis	osteopetrosis	NN
cord-310847-63gh2tg4	184	48	and	and	CC
cord-310847-63gh2tg4	184	49	neurodegeneration	neurodegeneration	NN
cord-310847-63gh2tg4	184	50	,	,	,
cord-310847-63gh2tg4	184	51	and	and	CC
cord-310847-63gh2tg4	184	52	possibly	possibly	RB
cord-310847-63gh2tg4	184	53	epilepsy	epilepsy	VB
cord-310847-63gh2tg4	184	54	.	.	.
cord-310847-63gh2tg4	185	1	91	91	CD
cord-310847-63gh2tg4	186	1	The	the	DT
cord-310847-63gh2tg4	186	2	side	side	NN
cord-310847-63gh2tg4	186	3	chain	chain	NN
cord-310847-63gh2tg4	186	4	of	of	IN
cord-310847-63gh2tg4	186	5	the	the	DT
cord-310847-63gh2tg4	186	6	aforementioned	aforementioned	JJ
cord-310847-63gh2tg4	186	7	critical	critical	JJ
cord-310847-63gh2tg4	186	8	glutamic	glutamic	NN
cord-310847-63gh2tg4	186	9	acid	acid	NN
cord-310847-63gh2tg4	186	10	occupies	occupy	VBZ
cord-310847-63gh2tg4	186	11	a	a	DT
cord-310847-63gh2tg4	186	12	third	third	JJ
cord-310847-63gh2tg4	186	13	Cl	Cl	NNP
cord-310847-63gh2tg4	186	14	−	−	NNP
cord-310847-63gh2tg4	186	15	ion	ion	NN
cord-310847-63gh2tg4	186	16	binding	bind	VBG
cord-310847-63gh2tg4	186	17	site	site	NN
cord-310847-63gh2tg4	186	18	in	in	IN
cord-310847-63gh2tg4	186	19	the	the	DT
cord-310847-63gh2tg4	186	20	closed	closed	JJ
cord-310847-63gh2tg4	186	21	state	state	NN
cord-310847-63gh2tg4	186	22	of	of	IN
cord-310847-63gh2tg4	186	23	the	the	DT
cord-310847-63gh2tg4	186	24	channel	channel	NN
cord-310847-63gh2tg4	186	25	and	and	CC
cord-310847-63gh2tg4	186	26	moves	move	NNS
cord-310847-63gh2tg4	186	27	away	away	RB
cord-310847-63gh2tg4	186	28	to	to	TO
cord-310847-63gh2tg4	186	29	allow	allow	VB
cord-310847-63gh2tg4	186	30	Cl	Cl	NNP
cord-310847-63gh2tg4	186	31	−	−	NNP
cord-310847-63gh2tg4	186	32	binding	bind	VBG
cord-310847-63gh2tg4	186	33	.	.	.
cord-310847-63gh2tg4	187	1	90	90	CD
cord-310847-63gh2tg4	187	2	Glutamic	glutamic	NN
cord-310847-63gh2tg4	187	3	acid	acid	NN
cord-310847-63gh2tg4	187	4	valve	valve	NN
cord-310847-63gh2tg4	187	5	.	.	.
cord-310847-63gh2tg4	188	1	Glutamic	glutamic	NN
cord-310847-63gh2tg4	188	2	acid	acid	NN
cord-310847-63gh2tg4	188	3	is	be	VBZ
cord-310847-63gh2tg4	188	4	known	know	VBN
cord-310847-63gh2tg4	188	5	to	to	TO
cord-310847-63gh2tg4	188	6	play	play	VB
cord-310847-63gh2tg4	188	7	a	a	DT
cord-310847-63gh2tg4	188	8	unique	unique	JJ
cord-310847-63gh2tg4	188	9	role	role	NN
cord-310847-63gh2tg4	188	10	in	in	IN
cord-310847-63gh2tg4	188	11	regulation	regulation	NN
cord-310847-63gh2tg4	188	12	of	of	IN
cord-310847-63gh2tg4	188	13	the	the	DT
cord-310847-63gh2tg4	188	14	cytochrome	cytochrome	NN
cord-310847-63gh2tg4	188	15	-	-	HYPH
cord-310847-63gh2tg4	188	16	c	c	NN
cord-310847-63gh2tg4	188	17	oxidase	oxidase	NN
cord-310847-63gh2tg4	188	18	(	(	-LRB-
cord-310847-63gh2tg4	188	19	CcO	CcO	NNP
cord-310847-63gh2tg4	188	20	)	)	-RRB-
cord-310847-63gh2tg4	188	21	activity	activity	NN
cord-310847-63gh2tg4	188	22	.	.	.
cord-310847-63gh2tg4	189	1	CcO	CcO	NNP
cord-310847-63gh2tg4	189	2	is	be	VBZ
cord-310847-63gh2tg4	189	3	the	the	DT
cord-310847-63gh2tg4	189	4	last	last	JJ
cord-310847-63gh2tg4	189	5	enzyme	enzyme	NN
cord-310847-63gh2tg4	189	6	of	of	IN
cord-310847-63gh2tg4	189	7	the	the	DT
cord-310847-63gh2tg4	189	8	respiratory	respiratory	JJ
cord-310847-63gh2tg4	189	9	electron	electron	NN
cord-310847-63gh2tg4	189	10	transport	transport	NN
cord-310847-63gh2tg4	189	11	chain	chain	NN
cord-310847-63gh2tg4	189	12	in	in	IN
cord-310847-63gh2tg4	189	13	mitochondria	mitochondrion	NNS
cord-310847-63gh2tg4	189	14	(	(	-LRB-
cord-310847-63gh2tg4	189	15	or	or	CC
cord-310847-63gh2tg4	189	16	bacteria	bacteria	NNS
cord-310847-63gh2tg4	189	17	)	)	-RRB-
cord-310847-63gh2tg4	189	18	located	locate	VBN
cord-310847-63gh2tg4	189	19	in	in	IN
cord-310847-63gh2tg4	189	20	the	the	DT
cord-310847-63gh2tg4	189	21	inner	inner	JJ
cord-310847-63gh2tg4	189	22	mitochondrial	mitochondrial	NN
cord-310847-63gh2tg4	189	23	(	(	-LRB-
cord-310847-63gh2tg4	189	24	or	or	CC
cord-310847-63gh2tg4	189	25	bacterial	bacterial	JJ
cord-310847-63gh2tg4	189	26	)	)	-RRB-
cord-310847-63gh2tg4	189	27	membrane	membrane	NN
cord-310847-63gh2tg4	189	28	,	,	,
cord-310847-63gh2tg4	189	29	and	and	CC
cord-310847-63gh2tg4	189	30	it	-PRON-	PRP
cord-310847-63gh2tg4	189	31	is	be	VBZ
cord-310847-63gh2tg4	189	32	responsible	responsible	JJ
cord-310847-63gh2tg4	189	33	for	for	IN
cord-310847-63gh2tg4	189	34	reducing	reduce	VBG
cord-310847-63gh2tg4	189	35	~90	~90	CD
cord-310847-63gh2tg4	189	36	%	%	NN
cord-310847-63gh2tg4	189	37	of	of	IN
cord-310847-63gh2tg4	189	38	the	the	DT
cord-310847-63gh2tg4	189	39	oxygen	oxygen	NN
cord-310847-63gh2tg4	189	40	taken	take	VBN
cord-310847-63gh2tg4	189	41	up	up	RP
cord-310847-63gh2tg4	189	42	in	in	IN
cord-310847-63gh2tg4	189	43	aerobic	aerobic	JJ
cord-310847-63gh2tg4	189	44	life	life	NN
cord-310847-63gh2tg4	189	45	.	.	.
cord-310847-63gh2tg4	190	1	This	this	DT
cord-310847-63gh2tg4	190	2	protein	protein	NN
cord-310847-63gh2tg4	190	3	powers	power	VBZ
cord-310847-63gh2tg4	190	4	the	the	DT
cord-310847-63gh2tg4	190	5	production	production	NN
cord-310847-63gh2tg4	190	6	of	of	IN
cord-310847-63gh2tg4	190	7	ATP	ATP	NNP
cord-310847-63gh2tg4	190	8	by	by	IN
cord-310847-63gh2tg4	190	9	generating	generate	VBG
cord-310847-63gh2tg4	190	10	an	an	DT
cord-310847-63gh2tg4	190	11	electrochemical	electrochemical	JJ
cord-310847-63gh2tg4	190	12	proton	proton	NN
cord-310847-63gh2tg4	190	13	gradient	gradient	NN
cord-310847-63gh2tg4	190	14	across	across	IN
cord-310847-63gh2tg4	190	15	the	the	DT
cord-310847-63gh2tg4	190	16	membrane	membrane	NN
cord-310847-63gh2tg4	190	17	via	via	IN
cord-310847-63gh2tg4	190	18	the	the	DT
cord-310847-63gh2tg4	190	19	catalysis	catalysis	NN
cord-310847-63gh2tg4	190	20	of	of	IN
cord-310847-63gh2tg4	190	21	the	the	DT
cord-310847-63gh2tg4	190	22	oxygen	oxygen	NN
cord-310847-63gh2tg4	190	23	reduction	reduction	NN
cord-310847-63gh2tg4	190	24	to	to	IN
cord-310847-63gh2tg4	190	25	water	water	NN
cord-310847-63gh2tg4	190	26	that	that	WDT
cord-310847-63gh2tg4	190	27	takes	take	VBZ
cord-310847-63gh2tg4	190	28	place	place	NN
cord-310847-63gh2tg4	190	29	in	in	IN
cord-310847-63gh2tg4	190	30	the	the	DT
cord-310847-63gh2tg4	190	31	binuclear	binuclear	NNP
cord-310847-63gh2tg4	190	32	center	center	NN
cord-310847-63gh2tg4	190	33	(	(	-LRB-
cord-310847-63gh2tg4	190	34	BNC	BNC	NNP
cord-310847-63gh2tg4	190	35	)	)	-RRB-
cord-310847-63gh2tg4	190	36	of	of	IN
cord-310847-63gh2tg4	190	37	the	the	DT
cord-310847-63gh2tg4	190	38	enzyme	enzyme	NN
cord-310847-63gh2tg4	190	39	.	.	.
cord-310847-63gh2tg4	191	1	CcO	CcO	NNP
cord-310847-63gh2tg4	191	2	uses	use	VBZ
cord-310847-63gh2tg4	191	3	four	four	CD
cord-310847-63gh2tg4	191	4	electrons	electron	NNS
cord-310847-63gh2tg4	191	5	taken	take	VBN
cord-310847-63gh2tg4	191	6	up	up	RP
cord-310847-63gh2tg4	191	7	from	from	IN
cord-310847-63gh2tg4	191	8	the	the	DT
cord-310847-63gh2tg4	191	9	cytochrome	cytochrome	NN
cord-310847-63gh2tg4	191	10	c	c	NN
cord-310847-63gh2tg4	191	11	located	locate	VBN
cord-310847-63gh2tg4	191	12	at	at	IN
cord-310847-63gh2tg4	191	13	the	the	DT
cord-310847-63gh2tg4	191	14	positively	positively	RB
cord-310847-63gh2tg4	191	15	charged	charge	VBN
cord-310847-63gh2tg4	191	16	P	p	NN
cord-310847-63gh2tg4	191	17	-	-	HYPH
cord-310847-63gh2tg4	191	18	side	side	NN
cord-310847-63gh2tg4	191	19	(	(	-LRB-
cord-310847-63gh2tg4	191	20	outside	outside	NN
cord-310847-63gh2tg4	191	21	)	)	-RRB-
cord-310847-63gh2tg4	191	22	of	of	IN
cord-310847-63gh2tg4	191	23	the	the	DT
cord-310847-63gh2tg4	191	24	membrane	membrane	NN
cord-310847-63gh2tg4	191	25	and	and	CC
cord-310847-63gh2tg4	191	26	four	four	CD
cord-310847-63gh2tg4	191	27	"	"	``
cord-310847-63gh2tg4	191	28	chemical	chemical	NN
cord-310847-63gh2tg4	191	29	"	"	''
cord-310847-63gh2tg4	191	30	protons	proton	NNS
cord-310847-63gh2tg4	191	31	taken	take	VBN
cord-310847-63gh2tg4	191	32	from	from	IN
cord-310847-63gh2tg4	191	33	the	the	DT
cord-310847-63gh2tg4	191	34	negatively	negatively	RB
cord-310847-63gh2tg4	191	35	charged	charge	VBN
cord-310847-63gh2tg4	191	36	N	n	CD
cord-310847-63gh2tg4	191	37	-	-	HYPH
cord-310847-63gh2tg4	191	38	side	side	NN
cord-310847-63gh2tg4	191	39	(	(	-LRB-
cord-310847-63gh2tg4	191	40	inside	inside	RB
cord-310847-63gh2tg4	191	41	)	)	-RRB-
cord-310847-63gh2tg4	191	42	to	to	TO
cord-310847-63gh2tg4	191	43	reduce	reduce	VB
cord-310847-63gh2tg4	191	44	the	the	DT
cord-310847-63gh2tg4	191	45	dioxygen	dioxygen	NN
cord-310847-63gh2tg4	191	46	to	to	IN
cord-310847-63gh2tg4	191	47	two	two	CD
cord-310847-63gh2tg4	191	48	water	water	NN
cord-310847-63gh2tg4	191	49	molecules	molecule	NNS
cord-310847-63gh2tg4	191	50	.	.	.
cord-310847-63gh2tg4	192	1	In	in	IN
cord-310847-63gh2tg4	192	2	addition	addition	NN
cord-310847-63gh2tg4	192	3	to	to	IN
cord-310847-63gh2tg4	192	4	this	this	DT
cord-310847-63gh2tg4	192	5	oxygen	oxygen	NN
cord-310847-63gh2tg4	192	6	reduction	reduction	NN
cord-310847-63gh2tg4	192	7	reaction	reaction	NN
cord-310847-63gh2tg4	192	8	,	,	,
cord-310847-63gh2tg4	192	9	four	four	CD
cord-310847-63gh2tg4	192	10	"	"	``
cord-310847-63gh2tg4	192	11	pump	pump	NN
cord-310847-63gh2tg4	192	12	"	"	''
cord-310847-63gh2tg4	192	13	protons	proton	NNS
cord-310847-63gh2tg4	192	14	are	be	VBP
cord-310847-63gh2tg4	192	15	translocated	translocate	VBN
cord-310847-63gh2tg4	192	16	from	from	IN
cord-310847-63gh2tg4	192	17	the	the	DT
cord-310847-63gh2tg4	192	18	N	n	CD
cord-310847-63gh2tg4	192	19	-	-	HYPH
cord-310847-63gh2tg4	192	20	side	side	NN
cord-310847-63gh2tg4	192	21	to	to	IN
cord-310847-63gh2tg4	192	22	the	the	DT
cord-310847-63gh2tg4	192	23	P	p	NN
cord-310847-63gh2tg4	192	24	-	-	HYPH
cord-310847-63gh2tg4	192	25	side	side	NN
cord-310847-63gh2tg4	192	26	across	across	IN
cord-310847-63gh2tg4	192	27	the	the	DT
cord-310847-63gh2tg4	192	28	membrane	membrane	NN
cord-310847-63gh2tg4	192	29	against	against	IN
cord-310847-63gh2tg4	192	30	the	the	DT
cord-310847-63gh2tg4	192	31	opposing	oppose	VBG
cord-310847-63gh2tg4	192	32	membrane	membrane	NN
cord-310847-63gh2tg4	192	33	potential	potential	NN
cord-310847-63gh2tg4	192	34	,	,	,
cord-310847-63gh2tg4	192	35	doubling	double	VBG
cord-310847-63gh2tg4	192	36	the	the	DT
cord-310847-63gh2tg4	192	37	total	total	JJ
cord-310847-63gh2tg4	192	38	amount	amount	NN
cord-310847-63gh2tg4	192	39	of	of	IN
cord-310847-63gh2tg4	192	40	charge	charge	NN
cord-310847-63gh2tg4	192	41	separated	separate	VBN
cord-310847-63gh2tg4	192	42	by	by	IN
cord-310847-63gh2tg4	192	43	the	the	DT
cord-310847-63gh2tg4	192	44	enzyme	enzyme	NN
cord-310847-63gh2tg4	192	45	.	.	.
cord-310847-63gh2tg4	193	1	[	[	-LRB-
cord-310847-63gh2tg4	193	2	92	92	CD
cord-310847-63gh2tg4	193	3	]	]	-RRB-
cord-310847-63gh2tg4	193	4	[	[	-LRB-
cord-310847-63gh2tg4	193	5	93	93	CD
cord-310847-63gh2tg4	193	6	]	]	-RRB-
cord-310847-63gh2tg4	194	1	[	[	-LRB-
cord-310847-63gh2tg4	194	2	94	94	CD
cord-310847-63gh2tg4	194	3	]	]	-RRB-
cord-310847-63gh2tg4	194	4	[	[	-LRB-
cord-310847-63gh2tg4	194	5	95	95	CD
cord-310847-63gh2tg4	194	6	]	]	-RRB-
cord-310847-63gh2tg4	195	1	Therefore	therefore	RB
cord-310847-63gh2tg4	195	2	,	,	,
cord-310847-63gh2tg4	195	3	the	the	DT
cord-310847-63gh2tg4	195	4	main	main	JJ
cord-310847-63gh2tg4	195	5	role	role	NN
cord-310847-63gh2tg4	195	6	of	of	IN
cord-310847-63gh2tg4	195	7	CcO	CcO	NNP
cord-310847-63gh2tg4	195	8	is	be	VBZ
cord-310847-63gh2tg4	195	9	to	to	TO
cord-310847-63gh2tg4	195	10	serve	serve	VB
cord-310847-63gh2tg4	195	11	as	as	IN
cord-310847-63gh2tg4	195	12	a	a	DT
cord-310847-63gh2tg4	195	13	proton	proton	NN
cord-310847-63gh2tg4	195	14	pump	pump	NN
cord-310847-63gh2tg4	195	15	and	and	CC
cord-310847-63gh2tg4	195	16	a	a	DT
cord-310847-63gh2tg4	195	17	generator	generator	NN
cord-310847-63gh2tg4	195	18	of	of	IN
cord-310847-63gh2tg4	195	19	the	the	DT
cord-310847-63gh2tg4	195	20	electrochemical	electrochemical	JJ
cord-310847-63gh2tg4	195	21	proton	proton	NN
cord-310847-63gh2tg4	195	22	gradient	gradient	NN
cord-310847-63gh2tg4	195	23	or	or	CC
cord-310847-63gh2tg4	195	24	charge	charge	NN
cord-310847-63gh2tg4	195	25	separation	separation	NN
cord-310847-63gh2tg4	195	26	across	across	IN
cord-310847-63gh2tg4	195	27	the	the	DT
cord-310847-63gh2tg4	195	28	membrane	membrane	NN
cord-310847-63gh2tg4	195	29	,	,	,
cord-310847-63gh2tg4	195	30	which	which	WDT
cord-310847-63gh2tg4	195	31	is	be	VBZ
cord-310847-63gh2tg4	195	32	achieved	achieve	VBN
cord-310847-63gh2tg4	195	33	via	via	IN
cord-310847-63gh2tg4	195	34	two	two	CD
cord-310847-63gh2tg4	195	35	separate	separate	JJ
cord-310847-63gh2tg4	195	36	processes	process	NNS
cord-310847-63gh2tg4	195	37	.	.	.
cord-310847-63gh2tg4	196	1	First	first	RB
cord-310847-63gh2tg4	196	2	,	,	,
cord-310847-63gh2tg4	196	3	the	the	DT
cord-310847-63gh2tg4	196	4	reduction	reduction	NN
cord-310847-63gh2tg4	196	5	of	of	IN
cord-310847-63gh2tg4	196	6	oxygen	oxygen	NN
cord-310847-63gh2tg4	196	7	to	to	IN
cord-310847-63gh2tg4	196	8	water	water	NN
cord-310847-63gh2tg4	196	9	by	by	IN
cord-310847-63gh2tg4	196	10	electrons	electron	NNS
cord-310847-63gh2tg4	196	11	and	and	CC
cord-310847-63gh2tg4	196	12	protons	proton	NNS
cord-310847-63gh2tg4	196	13	taken	take	VBN
cord-310847-63gh2tg4	196	14	up	up	RP
cord-310847-63gh2tg4	196	15	from	from	IN
cord-310847-63gh2tg4	196	16	opposite	opposite	JJ
cord-310847-63gh2tg4	196	17	sides	side	NNS
cord-310847-63gh2tg4	196	18	of	of	IN
cord-310847-63gh2tg4	196	19	the	the	DT
cord-310847-63gh2tg4	196	20	membrane	membrane	NN
cord-310847-63gh2tg4	196	21	leads	lead	NNS
cord-310847-63gh2tg4	196	22	of	of	IN
cord-310847-63gh2tg4	196	23	aspartic	aspartic	JJ
cord-310847-63gh2tg4	196	24	acid	acid	NN
cord-310847-63gh2tg4	196	25	,	,	,
cord-310847-63gh2tg4	196	26	asparagine	asparagine	NN
cord-310847-63gh2tg4	196	27	,	,	,
cord-310847-63gh2tg4	196	28	serine	serine	NN
cord-310847-63gh2tg4	196	29	and	and	CC
cord-310847-63gh2tg4	196	30	threonine	threonine	NN
cord-310847-63gh2tg4	196	31	form	form	NN
cord-310847-63gh2tg4	196	32	hydrogen	hydrogen	NN
cord-310847-63gh2tg4	196	33	bonds	bond	NNS
cord-310847-63gh2tg4	196	34	with	with	IN
cord-310847-63gh2tg4	196	35	residues	residue	NNS
cord-310847-63gh2tg4	196	36	located	locate	VBN
cord-310847-63gh2tg4	196	37	close	close	RB
cord-310847-63gh2tg4	196	38	in	in	IN
cord-310847-63gh2tg4	196	39	sequence	sequence	NN
cord-310847-63gh2tg4	196	40	.	.	.
cord-310847-63gh2tg4	197	1	74	74	CD
cord-310847-63gh2tg4	197	2	Finally	finally	RB
cord-310847-63gh2tg4	197	3	,	,	,
cord-310847-63gh2tg4	197	4	based	base	VBN
cord-310847-63gh2tg4	197	5	on	on	IN
cord-310847-63gh2tg4	197	6	the	the	DT
cord-310847-63gh2tg4	197	7	analysis	analysis	NN
cord-310847-63gh2tg4	197	8	of	of	IN
cord-310847-63gh2tg4	197	9	α	α	NN
cord-310847-63gh2tg4	197	10	-	-	HYPH
cord-310847-63gh2tg4	197	11	helical	helical	JJ
cord-310847-63gh2tg4	197	12	propensity	propensity	NN
cord-310847-63gh2tg4	197	13	of	of	IN
cord-310847-63gh2tg4	197	14	a	a	DT
cord-310847-63gh2tg4	197	15	series	series	NN
cord-310847-63gh2tg4	197	16	of	of	IN
cord-310847-63gh2tg4	197	17	dodecapeptides	dodecapeptides	NNP
cord-310847-63gh2tg4	197	18	containing	contain	VBG
cord-310847-63gh2tg4	197	19	alanine	alanine	NNP
cord-310847-63gh2tg4	197	20	,	,	,
cord-310847-63gh2tg4	197	21	asparagine	asparagine	NN
cord-310847-63gh2tg4	197	22	,	,	,
cord-310847-63gh2tg4	197	23	aspartate	aspartate	NN
cord-310847-63gh2tg4	197	24	,	,	,
cord-310847-63gh2tg4	197	25	glutamine	glutamine	NN
cord-310847-63gh2tg4	197	26	,	,	,
cord-310847-63gh2tg4	197	27	glutamate	glutamate	NN
cord-310847-63gh2tg4	197	28	and	and	CC
cord-310847-63gh2tg4	197	29	serine	serine	NN
cord-310847-63gh2tg4	197	30	at	at	IN
cord-310847-63gh2tg4	197	31	the	the	DT
cord-310847-63gh2tg4	197	32	N	n	CD
cord-310847-63gh2tg4	197	33	-	-	HYPH
cord-310847-63gh2tg4	197	34	terminus	terminus	NN
cord-310847-63gh2tg4	197	35	and	and	CC
cord-310847-63gh2tg4	197	36	arginine	arginine	NN
cord-310847-63gh2tg4	197	37	,	,	,
cord-310847-63gh2tg4	197	38	lysine	lysine	NN
cord-310847-63gh2tg4	197	39	and	and	CC
cord-310847-63gh2tg4	197	40	alanine	alanine	NN
cord-310847-63gh2tg4	197	41	at	at	IN
cord-310847-63gh2tg4	197	42	the	the	DT
cord-310847-63gh2tg4	197	43	C	C	NNP
cord-310847-63gh2tg4	197	44	-	-	HYPH
cord-310847-63gh2tg4	197	45	terminus	terminus	NN
cord-310847-63gh2tg4	197	46	,	,	,
cord-310847-63gh2tg4	197	47	it	-PRON-	PRP
cord-310847-63gh2tg4	197	48	was	be	VBD
cord-310847-63gh2tg4	197	49	concluded	conclude	VBN
cord-310847-63gh2tg4	197	50	that	that	IN
cord-310847-63gh2tg4	197	51	the	the	DT
cord-310847-63gh2tg4	197	52	α	α	NN
cord-310847-63gh2tg4	197	53	-	-	HYPH
cord-310847-63gh2tg4	197	54	helix	helix	NN
cord-310847-63gh2tg4	197	55	-	-	HYPH
cord-310847-63gh2tg4	197	56	stabilizing	stabilize	VBG
cord-310847-63gh2tg4	197	57	abilities	ability	NNS
cord-310847-63gh2tg4	197	58	of	of	IN
cord-310847-63gh2tg4	197	59	these	these	DT
cord-310847-63gh2tg4	197	60	residues	residue	NNS
cord-310847-63gh2tg4	197	61	can	can	MD
cord-310847-63gh2tg4	197	62	be	be	VB
cord-310847-63gh2tg4	197	63	ranged	range	VBN
cord-310847-63gh2tg4	197	64	as	as	IN
cord-310847-63gh2tg4	197	65	follows	follow	VBZ
cord-310847-63gh2tg4	197	66	:	:	:
cord-310847-63gh2tg4	198	1	aspartate	aspartate	NNP
cord-310847-63gh2tg4	198	2	>	>	XX
cord-310847-63gh2tg4	198	3	asparagine	asparagine	NN
cord-310847-63gh2tg4	199	1	>	>	XX
cord-310847-63gh2tg4	200	1	serine	serine	NN
cord-310847-63gh2tg4	200	2	>	>	XX
cord-310847-63gh2tg4	201	1	glutamate	glutamate	NN
cord-310847-63gh2tg4	202	1	>	>	XX
cord-310847-63gh2tg4	203	1	glutamine	glutamine	NN
cord-310847-63gh2tg4	203	2	>	>	XX
cord-310847-63gh2tg4	204	1	alanine	alanine	NNP
cord-310847-63gh2tg4	204	2	at	at	IN
cord-310847-63gh2tg4	204	3	the	the	DT
cord-310847-63gh2tg4	204	4	N	N	NNP
cord-310847-63gh2tg4	204	5	-	-	HYPH
cord-310847-63gh2tg4	204	6	terminus	terminus	NN
cord-310847-63gh2tg4	204	7	and	and	CC
cord-310847-63gh2tg4	204	8	arginine	arginine	NN
cord-310847-63gh2tg4	205	1	>	>	XX
cord-310847-63gh2tg4	206	1	lysine	lysine	NNP
cord-310847-63gh2tg4	206	2	>	>	XX
cord-310847-63gh2tg4	206	3	alanine	alanine	NN
cord-310847-63gh2tg4	206	4	at	at	IN
cord-310847-63gh2tg4	206	5	the	the	DT
cord-310847-63gh2tg4	206	6	C	C	NNP
cord-310847-63gh2tg4	206	7	-	-	HYPH
cord-310847-63gh2tg4	206	8	terminus	terminus	NN
cord-310847-63gh2tg4	206	9	.	.	.
cord-310847-63gh2tg4	207	1	75	75	CD
cord-310847-63gh2tg4	207	2	Glutamic	glutamic	NN
cord-310847-63gh2tg4	207	3	acid	acid	NN
cord-310847-63gh2tg4	207	4	and	and	CC
cord-310847-63gh2tg4	207	5	protein	protein	NN
cord-310847-63gh2tg4	207	6	solubility	solubility	NN
cord-310847-63gh2tg4	207	7	.	.	.
cord-310847-63gh2tg4	208	1	Based	base	VBN
cord-310847-63gh2tg4	208	2	on	on	IN
cord-310847-63gh2tg4	208	3	the	the	DT
cord-310847-63gh2tg4	208	4	analysis	analysis	NN
cord-310847-63gh2tg4	208	5	of	of	IN
cord-310847-63gh2tg4	208	6	solubility	solubility	NN
cord-310847-63gh2tg4	208	7	-	-	HYPH
cord-310847-63gh2tg4	208	8	changing	change	VBG
cord-310847-63gh2tg4	208	9	substitutions	substitution	NNS
cord-310847-63gh2tg4	208	10	in	in	IN
cord-310847-63gh2tg4	208	11	proteins	protein	NNS
cord-310847-63gh2tg4	208	12	it	-PRON-	PRP
cord-310847-63gh2tg4	208	13	has	have	VBZ
cord-310847-63gh2tg4	208	14	been	be	VBN
cord-310847-63gh2tg4	208	15	pointed	point	VBN
cord-310847-63gh2tg4	208	16	out	out	RP
cord-310847-63gh2tg4	208	17	that	that	IN
cord-310847-63gh2tg4	208	18	together	together	RB
cord-310847-63gh2tg4	208	19	with	with	IN
cord-310847-63gh2tg4	208	20	two	two	CD
cord-310847-63gh2tg4	208	21	other	other	JJ
cord-310847-63gh2tg4	208	22	hydrophilic	hydrophilic	JJ
cord-310847-63gh2tg4	208	23	residues	residue	NNS
cord-310847-63gh2tg4	208	24	(	(	-LRB-
cord-310847-63gh2tg4	208	25	aspartic	aspartic	JJ
cord-310847-63gh2tg4	208	26	acid	acid	NN
cord-310847-63gh2tg4	208	27	and	and	CC
cord-310847-63gh2tg4	208	28	serine	serine	NN
cord-310847-63gh2tg4	208	29	)	)	-RRB-
cord-310847-63gh2tg4	209	1	glutamic	glutamic	NN
cord-310847-63gh2tg4	209	2	acid	acid	NN
cord-310847-63gh2tg4	209	3	contributes	contribute	VBZ
cord-310847-63gh2tg4	209	4	significantly	significantly	RB
cord-310847-63gh2tg4	209	5	more	more	RBR
cord-310847-63gh2tg4	209	6	favorably	favorably	RB
cord-310847-63gh2tg4	209	7	to	to	IN
cord-310847-63gh2tg4	209	8	protein	protein	NN
cord-310847-63gh2tg4	209	9	solubility	solubility	NN
cord-310847-63gh2tg4	209	10	than	than	IN
cord-310847-63gh2tg4	209	11	other	other	JJ
cord-310847-63gh2tg4	209	12	hydrophilic	hydrophilic	JJ
cord-310847-63gh2tg4	209	13	residues	residue	NNS
cord-310847-63gh2tg4	209	14	(	(	-LRB-
cord-310847-63gh2tg4	209	15	asparagine	asparagine	NN
cord-310847-63gh2tg4	209	16	,	,	,
cord-310847-63gh2tg4	209	17	glutamine	glutamine	NN
cord-310847-63gh2tg4	209	18	,	,	,
cord-310847-63gh2tg4	209	19	threonine	threonine	NN
cord-310847-63gh2tg4	209	20	,	,	,
cord-310847-63gh2tg4	209	21	lysine	lysine	NN
cord-310847-63gh2tg4	209	22	and	and	CC
cord-310847-63gh2tg4	209	23	arginine	arginine	NN
cord-310847-63gh2tg4	209	24	)	)	-RRB-
cord-310847-63gh2tg4	209	25	.	.	.
cord-310847-63gh2tg4	210	1	76	76	CD
cord-310847-63gh2tg4	211	1	Based	base	VBN
cord-310847-63gh2tg4	211	2	on	on	IN
cord-310847-63gh2tg4	211	3	this	this	DT
cord-310847-63gh2tg4	211	4	observation	observation	NN
cord-310847-63gh2tg4	211	5	,	,	,
cord-310847-63gh2tg4	211	6	an	an	DT
cord-310847-63gh2tg4	211	7	important	important	JJ
cord-310847-63gh2tg4	211	8	strategy	strategy	NN
cord-310847-63gh2tg4	211	9	for	for	IN
cord-310847-63gh2tg4	211	10	solubility	solubility	NN
cord-310847-63gh2tg4	211	11	enhancement	enhancement	NN
cord-310847-63gh2tg4	211	12	was	be	VBD
cord-310847-63gh2tg4	211	13	proposed	propose	VBN
cord-310847-63gh2tg4	211	14	,	,	,
cord-310847-63gh2tg4	211	15	were	be	VBD
cord-310847-63gh2tg4	212	1	the	the	DT
cord-310847-63gh2tg4	212	2	hydrophilic	hydrophilic	JJ
cord-310847-63gh2tg4	212	3	residues	residue	NNS
cord-310847-63gh2tg4	212	4	that	that	WDT
cord-310847-63gh2tg4	212	5	do	do	VBP
cord-310847-63gh2tg4	212	6	not	not	RB
cord-310847-63gh2tg4	212	7	contribute	contribute	VB
cord-310847-63gh2tg4	212	8	favorably	favorably	RB
cord-310847-63gh2tg4	212	9	to	to	IN
cord-310847-63gh2tg4	212	10	protein	protein	NN
cord-310847-63gh2tg4	212	11	solubility	solubility	NN
cord-310847-63gh2tg4	212	12	can	can	MD
cord-310847-63gh2tg4	212	13	be	be	VB
cord-310847-63gh2tg4	212	14	replaced	replace	VBN
cord-310847-63gh2tg4	212	15	with	with	IN
cord-310847-63gh2tg4	212	16	the	the	DT
cord-310847-63gh2tg4	212	17	hydrophilic	hydrophilic	JJ
cord-310847-63gh2tg4	212	18	residues	residue	NNS
cord-310847-63gh2tg4	212	19	that	that	WDT
cord-310847-63gh2tg4	212	20	contribute	contribute	VBP
cord-310847-63gh2tg4	212	21	more	more	RBR
cord-310847-63gh2tg4	212	22	favorably	favorably	RB
cord-310847-63gh2tg4	212	23	.	.	.
cord-310847-63gh2tg4	213	1	76	76	CD
cord-310847-63gh2tg4	214	1	Glutamic	glutamic	NN
cord-310847-63gh2tg4	214	2	acids	acid	NNS
cord-310847-63gh2tg4	214	3	inside	inside	IN
cord-310847-63gh2tg4	214	4	the	the	DT
cord-310847-63gh2tg4	214	5	pores	pore	NNS
cord-310847-63gh2tg4	214	6	of	of	IN
cord-310847-63gh2tg4	214	7	ion	ion	NN
cord-310847-63gh2tg4	214	8	channels	channel	NNS
cord-310847-63gh2tg4	214	9	.	.	.
cord-310847-63gh2tg4	215	1	Being	be	VBG
cord-310847-63gh2tg4	215	2	negatively	negatively	RB
cord-310847-63gh2tg4	215	3	charged	charge	VBN
cord-310847-63gh2tg4	215	4	at	at	IN
cord-310847-63gh2tg4	215	5	physiological	physiological	JJ
cord-310847-63gh2tg4	215	6	pH	ph	NN
cord-310847-63gh2tg4	215	7	,	,	,
cord-310847-63gh2tg4	215	8	glutamic	glutamic	JJ
cord-310847-63gh2tg4	215	9	acid	acid	NN
cord-310847-63gh2tg4	215	10	is	be	VBZ
cord-310847-63gh2tg4	215	11	perfectly	perfectly	RB
cord-310847-63gh2tg4	215	12	suited	suited	JJ
cord-310847-63gh2tg4	215	13	for	for	IN
cord-310847-63gh2tg4	215	14	binding	bind	VBG
cord-310847-63gh2tg4	215	15	metal	metal	NN
cord-310847-63gh2tg4	215	16	ions	ion	NNS
cord-310847-63gh2tg4	215	17	.	.	.
cord-310847-63gh2tg4	216	1	This	this	DT
cord-310847-63gh2tg4	216	2	property	property	NN
cord-310847-63gh2tg4	216	3	is	be	VBZ
cord-310847-63gh2tg4	216	4	used	use	VBN
cord-310847-63gh2tg4	216	5	in	in	IN
cord-310847-63gh2tg4	216	6	specific	specific	JJ
cord-310847-63gh2tg4	216	7	regulation	regulation	NN
cord-310847-63gh2tg4	216	8	of	of	IN
cord-310847-63gh2tg4	216	9	a	a	DT
cord-310847-63gh2tg4	216	10	variety	variety	NN
cord-310847-63gh2tg4	216	11	of	of	IN
cord-310847-63gh2tg4	216	12	ion	ion	NN
cord-310847-63gh2tg4	216	13	channels	channel	NNS
cord-310847-63gh2tg4	216	14	.	.	.
cord-310847-63gh2tg4	217	1	For	for	IN
cord-310847-63gh2tg4	217	2	example	example	NN
cord-310847-63gh2tg4	217	3	,	,	,
cord-310847-63gh2tg4	217	4	in	in	IN
cord-310847-63gh2tg4	217	5	cyclic	cyclic	JJ
cord-310847-63gh2tg4	217	6	nucleotide	nucleotide	RB
cord-310847-63gh2tg4	217	7	-	-	HYPH
cord-310847-63gh2tg4	217	8	gated	gate	VBN
cord-310847-63gh2tg4	217	9	(	(	-LRB-
cord-310847-63gh2tg4	217	10	CNG	CNG	NNP
cord-310847-63gh2tg4	217	11	)	)	-RRB-
cord-310847-63gh2tg4	217	12	channels	channel	NNS
cord-310847-63gh2tg4	217	13	(	(	-LRB-
cord-310847-63gh2tg4	217	14	which	which	WDT
cord-310847-63gh2tg4	217	15	are	be	VBP
cord-310847-63gh2tg4	217	16	found	find	VBN
cord-310847-63gh2tg4	217	17	in	in	IN
cord-310847-63gh2tg4	217	18	vertebrate	vertebrate	JJ
cord-310847-63gh2tg4	217	19	photoreceptors	photoreceptor	NNS
cord-310847-63gh2tg4	217	20	and	and	CC
cord-310847-63gh2tg4	217	21	olfactory	olfactory	JJ
cord-310847-63gh2tg4	217	22	epithelium	epithelium	NN
cord-310847-63gh2tg4	217	23	,	,	,
cord-310847-63gh2tg4	217	24	77	77	CD
cord-310847-63gh2tg4	217	25	elsewhere	elsewhere	RB
cord-310847-63gh2tg4	217	26	in	in	IN
cord-310847-63gh2tg4	217	27	the	the	DT
cord-310847-63gh2tg4	217	28	nervous	nervous	JJ
cord-310847-63gh2tg4	217	29	system	system	NN
cord-310847-63gh2tg4	217	30	[	[	-LRB-
cord-310847-63gh2tg4	217	31	78	78	CD
cord-310847-63gh2tg4	217	32	]	]	-RRB-
cord-310847-63gh2tg4	217	33	[	[	-LRB-
cord-310847-63gh2tg4	217	34	79	79	CD
cord-310847-63gh2tg4	217	35	]	]	-RRB-
cord-310847-63gh2tg4	217	36	[	[	-LRB-
cord-310847-63gh2tg4	217	37	80	80	CD
cord-310847-63gh2tg4	217	38	]	]	-RRB-
cord-310847-63gh2tg4	217	39	and	and	CC
cord-310847-63gh2tg4	217	40	in	in	IN
cord-310847-63gh2tg4	217	41	a	a	DT
cord-310847-63gh2tg4	217	42	variety	variety	NN
cord-310847-63gh2tg4	217	43	of	of	IN
cord-310847-63gh2tg4	217	44	other	other	JJ
cord-310847-63gh2tg4	217	45	cell	cell	NN
cord-310847-63gh2tg4	217	46	types	type	NNS
cord-310847-63gh2tg4	217	47	including	include	VBG
cord-310847-63gh2tg4	217	48	kidney	kidney	NN
cord-310847-63gh2tg4	217	49	,	,	,
cord-310847-63gh2tg4	217	50	testis	testis	NN
cord-310847-63gh2tg4	217	51	and	and	CC
cord-310847-63gh2tg4	217	52	heart	heart	NN
cord-310847-63gh2tg4	217	53	,	,	,
cord-310847-63gh2tg4	217	54	81	81	CD
cord-310847-63gh2tg4	217	55	and	and	CC
cord-310847-63gh2tg4	217	56	whose	whose	WP$
cord-310847-63gh2tg4	217	57	activation	activation	NN
cord-310847-63gh2tg4	217	58	represents	represent	VBZ
cord-310847-63gh2tg4	217	59	the	the	DT
cord-310847-63gh2tg4	217	60	final	final	JJ
cord-310847-63gh2tg4	217	61	step	step	NN
cord-310847-63gh2tg4	217	62	in	in	IN
cord-310847-63gh2tg4	217	63	the	the	DT
cord-310847-63gh2tg4	217	64	transduction	transduction	NN
cord-310847-63gh2tg4	217	65	pathways	pathway	NNS
cord-310847-63gh2tg4	217	66	in	in	IN
cord-310847-63gh2tg4	217	67	both	both	DT
cord-310847-63gh2tg4	217	68	vision	vision	NN
cord-310847-63gh2tg4	217	69	and	and	CC
cord-310847-63gh2tg4	217	70	olfaction	olfaction	NN
cord-310847-63gh2tg4	217	71	[	[	-LRB-
cord-310847-63gh2tg4	217	72	82	82	CD
cord-310847-63gh2tg4	217	73	]	]	-RRB-
cord-310847-63gh2tg4	217	74	[	[	-LRB-
cord-310847-63gh2tg4	217	75	83	83	CD
cord-310847-63gh2tg4	217	76	]	]	-RRB-
cord-310847-63gh2tg4	217	77	[	[	-LRB-
cord-310847-63gh2tg4	217	78	84	84	CD
cord-310847-63gh2tg4	217	79	]	]	-RRB-
cord-310847-63gh2tg4	217	80	)	)	-RRB-
cord-310847-63gh2tg4	217	81	,	,	.
cord-310847-63gh2tg4	218	1	a	a	DT
cord-310847-63gh2tg4	218	2	single	single	JJ
cord-310847-63gh2tg4	218	3	glutamic	glutamic	NN
cord-310847-63gh2tg4	218	4	acid	acid	NN
cord-310847-63gh2tg4	218	5	strategically	strategically	RB
cord-310847-63gh2tg4	218	6	located	locate	VBN
cord-310847-63gh2tg4	218	7	in	in	IN
cord-310847-63gh2tg4	218	8	the	the	DT
cord-310847-63gh2tg4	218	9	pore	pore	NN
cord-310847-63gh2tg4	218	10	represents	represent	VBZ
cord-310847-63gh2tg4	218	11	the	the	DT
cord-310847-63gh2tg4	218	12	binding	binding	NN
cord-310847-63gh2tg4	218	13	site	site	NN
cord-310847-63gh2tg4	218	14	for	for	IN
cord-310847-63gh2tg4	218	15	multiple	multiple	JJ
cord-310847-63gh2tg4	218	16	monovalent	monovalent	JJ
cord-310847-63gh2tg4	218	17	cations	cation	NNS
cord-310847-63gh2tg4	218	18	,	,	,
cord-310847-63gh2tg4	218	19	the	the	DT
cord-310847-63gh2tg4	218	20	blocking	block	VBG
cord-310847-63gh2tg4	218	21	site	site	NN
cord-310847-63gh2tg4	218	22	for	for	IN
cord-310847-63gh2tg4	218	23	external	external	JJ
cord-310847-63gh2tg4	218	24	divalent	divalent	JJ
cord-310847-63gh2tg4	218	25	cations	cation	NNS
cord-310847-63gh2tg4	218	26	and	and	CC
cord-310847-63gh2tg4	218	27	the	the	DT
cord-310847-63gh2tg4	218	28	site	site	NN
cord-310847-63gh2tg4	218	29	for	for	IN
cord-310847-63gh2tg4	218	30	the	the	DT
cord-310847-63gh2tg4	218	31	effect	effect	NN
cord-310847-63gh2tg4	218	32	of	of	IN
cord-310847-63gh2tg4	218	33	protons	proton	NNS
cord-310847-63gh2tg4	218	34	on	on	IN
cord-310847-63gh2tg4	218	35	permeation	permeation	NN
cord-310847-63gh2tg4	218	36	.	.	.
cord-310847-63gh2tg4	219	1	82	82	CD
cord-310847-63gh2tg4	220	1	This	this	DT
cord-310847-63gh2tg4	220	2	is	be	VBZ
cord-310847-63gh2tg4	220	3	not	not	RB
cord-310847-63gh2tg4	220	4	too	too	RB
cord-310847-63gh2tg4	220	5	surprising	surprising	JJ
cord-310847-63gh2tg4	220	6	since	since	IN
cord-310847-63gh2tg4	220	7	the	the	DT
cord-310847-63gh2tg4	220	8	pore	pore	NN
cord-310847-63gh2tg4	220	9	region	region	NN
cord-310847-63gh2tg4	220	10	of	of	IN
cord-310847-63gh2tg4	220	11	the	the	DT
cord-310847-63gh2tg4	220	12	channel	channel	NN
cord-310847-63gh2tg4	220	13	controls	control	VBZ
cord-310847-63gh2tg4	220	14	both	both	CC
cord-310847-63gh2tg4	220	15	the	the	DT
cord-310847-63gh2tg4	220	16	singlechannel	singlechannel	NNP
cord-310847-63gh2tg4	220	17	conductance	conductance	NN
cord-310847-63gh2tg4	220	18	and	and	CC
cord-310847-63gh2tg4	220	19	the	the	DT
cord-310847-63gh2tg4	220	20	pore	pore	NN
cord-310847-63gh2tg4	220	21	diameter	diameter	NN
cord-310847-63gh2tg4	220	22	of	of	IN
cord-310847-63gh2tg4	220	23	the	the	DT
cord-310847-63gh2tg4	220	24	channel	channel	NN
cord-310847-63gh2tg4	220	25	.	.	.
cord-310847-63gh2tg4	221	1	85	85	CD
cord-310847-63gh2tg4	222	1	Importantly	importantly	RB
cord-310847-63gh2tg4	222	2	,	,	,
cord-310847-63gh2tg4	222	3	CNG	CNG	NNP
cord-310847-63gh2tg4	222	4	channels	channel	NNS
cord-310847-63gh2tg4	222	5	are	be	VBP
cord-310847-63gh2tg4	222	6	permeable	permeable	JJ
cord-310847-63gh2tg4	222	7	to	to	IN
cord-310847-63gh2tg4	222	8	Ca	Ca	NNP
cord-310847-63gh2tg4	222	9	2	2	CD
cord-310847-63gh2tg4	222	10	+	+	CC
cord-310847-63gh2tg4	222	11	,	,	,
cord-310847-63gh2tg4	222	12	which	which	WDT
cord-310847-63gh2tg4	222	13	is	be	VBZ
cord-310847-63gh2tg4	222	14	an	an	DT
cord-310847-63gh2tg4	222	15	important	important	JJ
cord-310847-63gh2tg4	222	16	element	element	NN
cord-310847-63gh2tg4	222	17	in	in	IN
cord-310847-63gh2tg4	222	18	the	the	DT
cord-310847-63gh2tg4	222	19	activation	activation	NN
cord-310847-63gh2tg4	222	20	of	of	IN
cord-310847-63gh2tg4	222	21	intracellular	intracellular	JJ
cord-310847-63gh2tg4	222	22	targets	target	NNS
cord-310847-63gh2tg4	222	23	,	,	,
cord-310847-63gh2tg4	222	24	and	and	CC
cord-310847-63gh2tg4	222	25	which	which	WDT
cord-310847-63gh2tg4	222	26	in	in	IN
cord-310847-63gh2tg4	222	27	addition	addition	NN
cord-310847-63gh2tg4	222	28	to	to	IN
cord-310847-63gh2tg4	222	29	permeating	permeate	VBG
cord-310847-63gh2tg4	222	30	CNG	CNG	NNP
cord-310847-63gh2tg4	222	31	channels	channel	NNS
cord-310847-63gh2tg4	222	32	can	can	MD
cord-310847-63gh2tg4	222	33	profoundly	profoundly	RB
cord-310847-63gh2tg4	222	34	block	block	VB
cord-310847-63gh2tg4	222	35	the	the	DT
cord-310847-63gh2tg4	222	36	current	current	JJ
cord-310847-63gh2tg4	222	37	flow	flow	NN
cord-310847-63gh2tg4	222	38	carried	carry	VBN
cord-310847-63gh2tg4	222	39	by	by	IN
cord-310847-63gh2tg4	222	40	monovalent	monovalent	JJ
cord-310847-63gh2tg4	222	41	cations	cation	NNS
cord-310847-63gh2tg4	222	42	through	through	IN
cord-310847-63gh2tg4	222	43	the	the	DT
cord-310847-63gh2tg4	222	44	CNG	CNG	NNP
cord-310847-63gh2tg4	222	45	channels	channel	NNS
cord-310847-63gh2tg4	222	46	.	.	.
cord-310847-63gh2tg4	223	1	83	83	CD
cord-310847-63gh2tg4	224	1	This	this	DT
cord-310847-63gh2tg4	224	2	capability	capability	NN
cord-310847-63gh2tg4	224	3	of	of	IN
cord-310847-63gh2tg4	224	4	Ca	Ca	NNP
cord-310847-63gh2tg4	224	5	2	2	CD
cord-310847-63gh2tg4	224	6	+	+	SYM
cord-310847-63gh2tg4	224	7	to	to	TO
cord-310847-63gh2tg4	224	8	block	block	VB
cord-310847-63gh2tg4	224	9	the	the	DT
cord-310847-63gh2tg4	224	10	monovalent	monovalent	NNP
cord-310847-63gh2tg4	224	11	cation	cation	NNP
cord-310847-63gh2tg4	224	12	flow	flow	NNP
cord-310847-63gh2tg4	224	13	is	be	VBZ
cord-310847-63gh2tg4	224	14	determined	determine	VBN
cord-310847-63gh2tg4	224	15	by	by	IN
cord-310847-63gh2tg4	224	16	the	the	DT
cord-310847-63gh2tg4	224	17	high	high	JJ
cord-310847-63gh2tg4	224	18	-	-	HYPH
cord-310847-63gh2tg4	224	19	affinity	affinity	NN
cord-310847-63gh2tg4	224	20	binding	binding	NN
cord-310847-63gh2tg4	224	21	of	of	IN
cord-310847-63gh2tg4	224	22	Ca	Ca	NNP
cord-310847-63gh2tg4	224	23	2	2	CD
cord-310847-63gh2tg4	224	24	+	+	CC
cord-310847-63gh2tg4	224	25	to	to	IN
cord-310847-63gh2tg4	224	26	a	a	DT
cord-310847-63gh2tg4	224	27	single	single	JJ
cord-310847-63gh2tg4	224	28	acidic	acidic	JJ
cord-310847-63gh2tg4	224	29	amino	amino	NN
cord-310847-63gh2tg4	224	30	acid	acid	NN
cord-310847-63gh2tg4	224	31	residue	residue	NN
cord-310847-63gh2tg4	224	32	located	locate	VBN
cord-310847-63gh2tg4	224	33	in	in	IN
cord-310847-63gh2tg4	224	34	the	the	DT
cord-310847-63gh2tg4	224	35	pore	pore	NN
cord-310847-63gh2tg4	224	36	of	of	IN
cord-310847-63gh2tg4	224	37	the	the	DT
cord-310847-63gh2tg4	224	38	channel	channel	NN
cord-310847-63gh2tg4	224	39	,	,	,
cord-310847-63gh2tg4	224	40	which	which	WDT
cord-310847-63gh2tg4	224	41	is	be	VBZ
cord-310847-63gh2tg4	224	42	Glu363	glu363	CD
cord-310847-63gh2tg4	224	43	for	for	IN
cord-310847-63gh2tg4	224	44	the	the	DT
cord-310847-63gh2tg4	224	45	rod	rod	NNP
cord-310847-63gh2tg4	224	46	CNG	CNG	NNP
cord-310847-63gh2tg4	224	47	channel	channel	NNP
cord-310847-63gh2tg4	224	48	and	and	CC
cord-310847-63gh2tg4	224	49	Glu333	Glu333	.
cord-310847-63gh2tg4	224	50	for	for	IN
cord-310847-63gh2tg4	224	51	the	the	DT
cord-310847-63gh2tg4	224	52	catfish	catfish	NN
cord-310847-63gh2tg4	224	53	olfactory	olfactory	NN
cord-310847-63gh2tg4	224	54	CNG	CNG	NNP
cord-310847-63gh2tg4	224	55	channel	channel	NNP
cord-310847-63gh2tg4	224	56	.	.	.
cord-310847-63gh2tg4	225	1	86	86	CD
cord-310847-63gh2tg4	226	1	This	this	DT
cord-310847-63gh2tg4	226	2	same	same	JJ
cord-310847-63gh2tg4	226	3	glutamic	glutamic	NN
cord-310847-63gh2tg4	226	4	acid	acid	NN
cord-310847-63gh2tg4	226	5	residue	residue	NN
cord-310847-63gh2tg4	226	6	is	be	VBZ
cord-310847-63gh2tg4	226	7	also	also	RB
cord-310847-63gh2tg4	226	8	responsible	responsible	JJ
cord-310847-63gh2tg4	226	9	for	for	IN
cord-310847-63gh2tg4	226	10	the	the	DT
cord-310847-63gh2tg4	226	11	external	external	JJ
cord-310847-63gh2tg4	226	12	rapid	rapid	JJ
cord-310847-63gh2tg4	226	13	proton	proton	NN
cord-310847-63gh2tg4	226	14	block	block	NN
cord-310847-63gh2tg4	226	15	of	of	IN
cord-310847-63gh2tg4	226	16	CNG	CNG	NNP
cord-310847-63gh2tg4	226	17	channels	channel	NNS
cord-310847-63gh2tg4	226	18	,	,	,
cord-310847-63gh2tg4	226	19	another	another	DT
cord-310847-63gh2tg4	226	20	characteristic	characteristic	NN
cord-310847-63gh2tg4	226	21	that	that	IN
cord-310847-63gh2tg4	226	22	the	the	DT
cord-310847-63gh2tg4	226	23	CNG	CNG	NNP
cord-310847-63gh2tg4	226	24	channels	channel	NNS
cord-310847-63gh2tg4	226	25	share	share	VBP
cord-310847-63gh2tg4	226	26	with	with	IN
cord-310847-63gh2tg4	226	27	Ca	Ca	NNP
cord-310847-63gh2tg4	226	28	2	2	CD
cord-310847-63gh2tg4	226	29	+	+	SYM
cord-310847-63gh2tg4	226	30	channels	channel	NNS
cord-310847-63gh2tg4	226	31	.	.	.
cord-310847-63gh2tg4	227	1	86	86	CD
cord-310847-63gh2tg4	227	2	Glutamic	glutamic	NN
cord-310847-63gh2tg4	227	3	acid	acid	NN
cord-310847-63gh2tg4	227	4	also	also	RB
cord-310847-63gh2tg4	227	5	plays	play	VBZ
cord-310847-63gh2tg4	227	6	an	an	DT
cord-310847-63gh2tg4	227	7	important	important	JJ
cord-310847-63gh2tg4	227	8	regulatory	regulatory	JJ
cord-310847-63gh2tg4	227	9	role	role	NN
cord-310847-63gh2tg4	227	10	in	in	IN
cord-310847-63gh2tg4	227	11	the	the	DT
cord-310847-63gh2tg4	227	12	voltage	voltage	NN
cord-310847-63gh2tg4	227	13	-	-	HYPH
cord-310847-63gh2tg4	227	14	dependent	dependent	JJ
cord-310847-63gh2tg4	227	15	calcium	calcium	NN
cord-310847-63gh2tg4	227	16	channels	channel	NNS
cord-310847-63gh2tg4	227	17	that	that	WDT
cord-310847-63gh2tg4	227	18	are	be	VBP
cord-310847-63gh2tg4	227	19	located	locate	VBN
cord-310847-63gh2tg4	227	20	in	in	IN
cord-310847-63gh2tg4	227	21	the	the	DT
cord-310847-63gh2tg4	227	22	plasma	plasma	NN
cord-310847-63gh2tg4	227	23	membrane	membrane	NN
cord-310847-63gh2tg4	227	24	and	and	CC
cord-310847-63gh2tg4	227	25	form	form	VB
cord-310847-63gh2tg4	227	26	a	a	DT
cord-310847-63gh2tg4	227	27	highly	highly	RB
cord-310847-63gh2tg4	227	28	selective	selective	JJ
cord-310847-63gh2tg4	227	29	conduit	conduit	NN
cord-310847-63gh2tg4	227	30	by	by	IN
cord-310847-63gh2tg4	227	31	which	which	WDT
cord-310847-63gh2tg4	228	1	Ca	ca	NN
cord-310847-63gh2tg4	228	2	2	2	CD
cord-310847-63gh2tg4	228	3	+	+	SYM
cord-310847-63gh2tg4	228	4	ions	ion	NNS
cord-310847-63gh2tg4	228	5	enter	enter	VBP
cord-310847-63gh2tg4	228	6	all	all	DT
cord-310847-63gh2tg4	228	7	excitable	excitable	JJ
cord-310847-63gh2tg4	228	8	cells	cell	NNS
cord-310847-63gh2tg4	228	9	and	and	CC
cord-310847-63gh2tg4	228	10	some	some	DT
cord-310847-63gh2tg4	228	11	nonexcitable	nonexcitable	JJ
cord-310847-63gh2tg4	228	12	cells	cell	NNS
cord-310847-63gh2tg4	228	13	.	.	.
cord-310847-63gh2tg4	229	1	87	87	CD
cord-310847-63gh2tg4	230	1	For	for	IN
cord-310847-63gh2tg4	230	2	these	these	DT
cord-310847-63gh2tg4	230	3	channels	channel	NNS
cord-310847-63gh2tg4	230	4	to	to	TO
cord-310847-63gh2tg4	230	5	operate	operate	VB
cord-310847-63gh2tg4	230	6	,	,	,
cord-310847-63gh2tg4	230	7	Ca	Ca	NNP
cord-310847-63gh2tg4	230	8	2	2	CD
cord-310847-63gh2tg4	230	9	+	+	SYM
cord-310847-63gh2tg4	230	10	ions	ion	NNS
cord-310847-63gh2tg4	230	11	must	must	MD
cord-310847-63gh2tg4	230	12	enter	enter	VB
cord-310847-63gh2tg4	230	13	selectively	selectively	RB
cord-310847-63gh2tg4	230	14	through	through	IN
cord-310847-63gh2tg4	230	15	the	the	DT
cord-310847-63gh2tg4	230	16	pore	pore	NN
cord-310847-63gh2tg4	230	17	,	,	,
cord-310847-63gh2tg4	230	18	bypassing	bypass	VBG
cord-310847-63gh2tg4	230	19	competition	competition	NN
cord-310847-63gh2tg4	230	20	with	with	IN
cord-310847-63gh2tg4	230	21	other	other	JJ
cord-310847-63gh2tg4	230	22	extracellular	extracellular	JJ
cord-310847-63gh2tg4	230	23	ions	ion	NNS
cord-310847-63gh2tg4	230	24	.	.	.
cord-310847-63gh2tg4	231	1	The	the	DT
cord-310847-63gh2tg4	231	2	high	high	JJ
cord-310847-63gh2tg4	231	3	selectivity	selectivity	NN
cord-310847-63gh2tg4	231	4	of	of	IN
cord-310847-63gh2tg4	231	5	a	a	DT
cord-310847-63gh2tg4	231	6	unique	unique	JJ
cord-310847-63gh2tg4	231	7	Ca	Ca	NNP
cord-310847-63gh2tg4	231	8	2	2	CD
cord-310847-63gh2tg4	231	9	+	+	CC
cord-310847-63gh2tg4	231	10	filter	filter	NN
cord-310847-63gh2tg4	231	11	is	be	VBZ
cord-310847-63gh2tg4	231	12	determined	determine	VBN
cord-310847-63gh2tg4	231	13	pathway	pathway	NN
cord-310847-63gh2tg4	231	14	for	for	IN
cord-310847-63gh2tg4	231	15	protons	proton	NNS
cord-310847-63gh2tg4	231	16	utilized	utilize	VBN
cord-310847-63gh2tg4	231	17	in	in	IN
cord-310847-63gh2tg4	231	18	the	the	DT
cord-310847-63gh2tg4	231	19	catalytic	catalytic	JJ
cord-310847-63gh2tg4	231	20	NO	no	DT
cord-310847-63gh2tg4	231	21	reduction	reduction	NN
cord-310847-63gh2tg4	231	22	;	;	:
cord-310847-63gh2tg4	231	23	the	the	DT
cord-310847-63gh2tg4	231	24	carboxylate	carboxylate	NNP
cord-310847-63gh2tg4	231	25	group	group	NN
cord-310847-63gh2tg4	231	26	of	of	IN
cord-310847-63gh2tg4	231	27	Glu215	Glu215	NNP
cord-310847-63gh2tg4	231	28	,	,	,
cord-310847-63gh2tg4	231	29	which	which	WDT
cord-310847-63gh2tg4	231	30	is	be	VBZ
cord-310847-63gh2tg4	231	31	located	locate	VBN
cord-310847-63gh2tg4	231	32	at	at	IN
cord-310847-63gh2tg4	231	33	the	the	DT
cord-310847-63gh2tg4	231	34	backside	backside	NN
cord-310847-63gh2tg4	231	35	of	of	IN
cord-310847-63gh2tg4	231	36	Glu211	glu211	CD
cord-310847-63gh2tg4	231	37	,	,	,
cord-310847-63gh2tg4	231	38	contributes	contribute	VBZ
cord-310847-63gh2tg4	231	39	to	to	IN
cord-310847-63gh2tg4	231	40	the	the	DT
cord-310847-63gh2tg4	231	41	electro	electro	JJ
cord-310847-63gh2tg4	231	42	-	-	HYPH
cord-310847-63gh2tg4	231	43	negative	negative	JJ
cord-310847-63gh2tg4	231	44	environment	environment	NN
cord-310847-63gh2tg4	231	45	of	of	IN
cord-310847-63gh2tg4	231	46	the	the	DT
cord-310847-63gh2tg4	231	47	binuclear	binuclear	NNP
cord-310847-63gh2tg4	231	48	center	center	NN
cord-310847-63gh2tg4	231	49	of	of	IN
cord-310847-63gh2tg4	231	50	cNOR	cNOR	NNP
cord-310847-63gh2tg4	231	51	,	,	,
cord-310847-63gh2tg4	231	52	and	and	CC
cord-310847-63gh2tg4	231	53	to	to	IN
cord-310847-63gh2tg4	231	54	the	the	DT
cord-310847-63gh2tg4	231	55	low	low	JJ
cord-310847-63gh2tg4	231	56	redox	redox	NN
cord-310847-63gh2tg4	231	57	potential	potential	NN
cord-310847-63gh2tg4	231	58	of	of	IN
cord-310847-63gh2tg4	231	59	heme	heme	NN
cord-310847-63gh2tg4	231	60	b	b	NN
cord-310847-63gh2tg4	231	61	3	3	CD
cord-310847-63gh2tg4	231	62	iron	iron	NN
cord-310847-63gh2tg4	231	63	;	;	:
cord-310847-63gh2tg4	231	64	finally	finally	RB
cord-310847-63gh2tg4	231	65	Glu135	Glu135	NNS
cord-310847-63gh2tg4	231	66	and	and	CC
cord-310847-63gh2tg4	231	67	Glu138	Glu138	NNP
cord-310847-63gh2tg4	231	68	are	be	VBP
cord-310847-63gh2tg4	231	69	positioned	position	VBN
cord-310847-63gh2tg4	231	70	in	in	IN
cord-310847-63gh2tg4	231	71	the	the	DT
cord-310847-63gh2tg4	231	72	loop	loop	NN
cord-310847-63gh2tg4	231	73	connecting	connect	VBG
cord-310847-63gh2tg4	231	74	the	the	DT
cord-310847-63gh2tg4	231	75	transmembrane	transmembrane	NN
cord-310847-63gh2tg4	231	76	helices	helix	NNS
cord-310847-63gh2tg4	231	77	III	III	NNP
cord-310847-63gh2tg4	231	78	and	and	CC
cord-310847-63gh2tg4	231	79	IV	IV	NNP
cord-310847-63gh2tg4	231	80	,	,	,
cord-310847-63gh2tg4	231	81	with	with	IN
cord-310847-63gh2tg4	231	82	Glu135	Glu135	NNS
cord-310847-63gh2tg4	231	83	serving	serve	VBG
cord-310847-63gh2tg4	231	84	as	as	IN
cord-310847-63gh2tg4	231	85	one	one	CD
cord-310847-63gh2tg4	231	86	of	of	IN
cord-310847-63gh2tg4	231	87	the	the	DT
cord-310847-63gh2tg4	231	88	Ca	Ca	NNP
cord-310847-63gh2tg4	231	89	2	2	CD
cord-310847-63gh2tg4	231	90	+	+	SYM
cord-310847-63gh2tg4	231	91	ligands	ligand	NNS
cord-310847-63gh2tg4	231	92	(	(	-LRB-
cord-310847-63gh2tg4	231	93	which	which	WDT
cord-310847-63gh2tg4	231	94	is	be	VBZ
cord-310847-63gh2tg4	231	95	crucial	crucial	JJ
cord-310847-63gh2tg4	231	96	for	for	IN
cord-310847-63gh2tg4	231	97	maintaining	maintain	VBG
cord-310847-63gh2tg4	231	98	the	the	DT
cord-310847-63gh2tg4	231	99	configuration	configuration	NN
cord-310847-63gh2tg4	231	100	of	of	IN
cord-310847-63gh2tg4	231	101	heme	heme	NN
cord-310847-63gh2tg4	231	102	b	b	NN
cord-310847-63gh2tg4	231	103	and	and	CC
cord-310847-63gh2tg4	231	104	b	b	NN
cord-310847-63gh2tg4	231	105	3	3	CD
cord-310847-63gh2tg4	231	106	)	)	-RRB-
cord-310847-63gh2tg4	231	107	and	and	CC
cord-310847-63gh2tg4	231	108	assisting	assist	VBG
cord-310847-63gh2tg4	231	109	in	in	IN
cord-310847-63gh2tg4	231	110	the	the	DT
cord-310847-63gh2tg4	231	111	water	water	NN
cord-310847-63gh2tg4	231	112	-	-	HYPH
cord-310847-63gh2tg4	231	113	mediated	mediate	VBN
cord-310847-63gh2tg4	231	114	proton	proton	NN
cord-310847-63gh2tg4	231	115	transfer	transfer	NN
cord-310847-63gh2tg4	231	116	through	through	IN
cord-310847-63gh2tg4	231	117	interactions	interaction	NNS
cord-310847-63gh2tg4	231	118	with	with	IN
cord-310847-63gh2tg4	231	119	a	a	DT
cord-310847-63gh2tg4	231	120	number	number	NN
cord-310847-63gh2tg4	231	121	of	of	IN
cord-310847-63gh2tg4	231	122	water	water	NN
cord-310847-63gh2tg4	231	123	molecules	molecule	NNS
cord-310847-63gh2tg4	231	124	,	,	,
cord-310847-63gh2tg4	231	125	and	and	CC
cord-310847-63gh2tg4	231	126	with	with	IN
cord-310847-63gh2tg4	231	127	Glu138	glu138	ADD
cord-310847-63gh2tg4	231	128	serving	serve	VBG
cord-310847-63gh2tg4	231	129	as	as	IN
cord-310847-63gh2tg4	231	130	a	a	DT
cord-310847-63gh2tg4	231	131	key	key	JJ
cord-310847-63gh2tg4	231	132	residue	residue	NN
cord-310847-63gh2tg4	231	133	for	for	IN
cord-310847-63gh2tg4	231	134	maintaining	maintain	VBG
cord-310847-63gh2tg4	231	135	the	the	DT
cord-310847-63gh2tg4	231	136	unique	unique	JJ
cord-310847-63gh2tg4	231	137	conformation	conformation	NN
cord-310847-63gh2tg4	231	138	of	of	IN
cord-310847-63gh2tg4	231	139	the	the	DT
cord-310847-63gh2tg4	231	140	long	long	JJ
cord-310847-63gh2tg4	231	141	loop	loop	NN
cord-310847-63gh2tg4	231	142	through	through	IN
cord-310847-63gh2tg4	231	143	interactions	interaction	NNS
cord-310847-63gh2tg4	231	144	with	with	IN
cord-310847-63gh2tg4	231	145	the	the	DT
cord-310847-63gh2tg4	231	146	residues	residue	NNS
cord-310847-63gh2tg4	231	147	in	in	IN
cord-310847-63gh2tg4	231	148	transmembrane	transmembrane	NNP
cord-310847-63gh2tg4	231	149	helix	helix	NN
cord-310847-63gh2tg4	231	150	II	II	NNP
cord-310847-63gh2tg4	231	151	,	,	,
cord-310847-63gh2tg4	231	152	which	which	WDT
cord-310847-63gh2tg4	231	153	would	would	MD
cord-310847-63gh2tg4	231	154	stabilize	stabilize	VB
cord-310847-63gh2tg4	231	155	the	the	DT
cord-310847-63gh2tg4	231	156	coordination	coordination	NN
cord-310847-63gh2tg4	231	157	of	of	IN
cord-310847-63gh2tg4	231	158	Glu135	glu135	CD
cord-310847-63gh2tg4	231	159	to	to	IN
cord-310847-63gh2tg4	231	160	Ca	Ca	NNP
cord-310847-63gh2tg4	231	161	2	2	CD
cord-310847-63gh2tg4	232	1	+	+	UH
cord-310847-63gh2tg4	232	2	.	.	.
cord-310847-63gh2tg4	233	1	100	100	CD
cord-310847-63gh2tg4	233	2	Mono	mono	JJ
cord-310847-63gh2tg4	233	3	-	-	HYPH
cord-310847-63gh2tg4	233	4	ADP	adp	NN
cord-310847-63gh2tg4	233	5	-	-	HYPH
cord-310847-63gh2tg4	233	6	ribosyltransferase	ribosyltransferase	NNP
cord-310847-63gh2tg4	233	7	,	,	,
cord-310847-63gh2tg4	233	8	which	which	WDT
cord-310847-63gh2tg4	233	9	is	be	VBZ
cord-310847-63gh2tg4	233	10	responsible	responsible	JJ
cord-310847-63gh2tg4	233	11	for	for	IN
cord-310847-63gh2tg4	233	12	the	the	DT
cord-310847-63gh2tg4	233	13	mono	mono	JJ
cord-310847-63gh2tg4	233	14	-	-	HYPH
cord-310847-63gh2tg4	233	15	ADP	adp	NN
cord-310847-63gh2tg4	233	16	-	-	HYPH
cord-310847-63gh2tg4	233	17	ribosylation	ribosylation	NN
cord-310847-63gh2tg4	233	18	of	of	IN
cord-310847-63gh2tg4	233	19	proteins	protein	NNS
cord-310847-63gh2tg4	233	20	,	,	,
cord-310847-63gh2tg4	233	21	possesses	possess	VBZ
cord-310847-63gh2tg4	233	22	a	a	DT
cord-310847-63gh2tg4	233	23	critical	critical	JJ
cord-310847-63gh2tg4	233	24	glutamic	glutamic	NN
cord-310847-63gh2tg4	233	25	acid	acid	NN
cord-310847-63gh2tg4	233	26	at	at	IN
cord-310847-63gh2tg4	233	27	the	the	DT
cord-310847-63gh2tg4	233	28	catalytic	catalytic	JJ
cord-310847-63gh2tg4	233	29	cleft	cleft	NN
cord-310847-63gh2tg4	233	30	which	which	WDT
cord-310847-63gh2tg4	233	31	functions	function	VBZ
cord-310847-63gh2tg4	233	32	to	to	TO
cord-310847-63gh2tg4	233	33	position	position	VB
cord-310847-63gh2tg4	233	34	NAD	NAD	NNP
cord-310847-63gh2tg4	233	35	for	for	IN
cord-310847-63gh2tg4	233	36	nucleophilic	nucleophilic	JJ
cord-310847-63gh2tg4	233	37	attack	attack	NN
cord-310847-63gh2tg4	233	38	at	at	IN
cord-310847-63gh2tg4	233	39	the	the	DT
cord-310847-63gh2tg4	233	40	N	n	CD
cord-310847-63gh2tg4	233	41	-	-	HYPH
cord-310847-63gh2tg4	233	42	glycosidic	glycosidic	NN
cord-310847-63gh2tg4	233	43	linkage	linkage	NN
cord-310847-63gh2tg4	233	44	for	for	IN
cord-310847-63gh2tg4	233	45	either	either	CC
cord-310847-63gh2tg4	233	46	ADPribose	ADPribose	NNP
cord-310847-63gh2tg4	233	47	transfer	transfer	NN
cord-310847-63gh2tg4	233	48	or	or	CC
cord-310847-63gh2tg4	233	49	NAD	NAD	NNP
cord-310847-63gh2tg4	233	50	hydrolysis	hydrolysis	NN
cord-310847-63gh2tg4	233	51	.	.	.
cord-310847-63gh2tg4	234	1	101	101	CD
cord-310847-63gh2tg4	235	1	The	the	DT
cord-310847-63gh2tg4	235	2	pronounced	pronounced	JJ
cord-310847-63gh2tg4	235	3	Na	Na	NNP
cord-310847-63gh2tg4	235	4	+	+	CC
cord-310847-63gh2tg4	235	5	/K	/k	NN
cord-310847-63gh2tg4	235	6	+	+	CC
cord-310847-63gh2tg4	235	7	selectivity	selectivity	NN
cord-310847-63gh2tg4	235	8	of	of	IN
cord-310847-63gh2tg4	235	9	Na	Na	NNP
cord-310847-63gh2tg4	235	10	,	,	,
cord-310847-63gh2tg4	235	11	K	K	NNP
cord-310847-63gh2tg4	235	12	-	-	HYPH
cord-310847-63gh2tg4	235	13	ATPase	ATPase	NNP
cord-310847-63gh2tg4	235	14	relies	rely	VBZ
cord-310847-63gh2tg4	235	15	on	on	IN
cord-310847-63gh2tg4	235	16	the	the	DT
cord-310847-63gh2tg4	235	17	strategic	strategic	JJ
cord-310847-63gh2tg4	235	18	positioning	positioning	NN
cord-310847-63gh2tg4	235	19	of	of	IN
cord-310847-63gh2tg4	235	20	glutamic	glutamic	NN
cord-310847-63gh2tg4	235	21	acid	acid	NN
cord-310847-63gh2tg4	235	22	residues	residue	NNS
cord-310847-63gh2tg4	235	23	.	.	.
cord-310847-63gh2tg4	236	1	102	102	CD
cord-310847-63gh2tg4	237	1	Here	here	RB
cord-310847-63gh2tg4	237	2	,	,	,
cord-310847-63gh2tg4	237	3	intramembrane	intramembrane	NNP
cord-310847-63gh2tg4	237	4	Glu327	glu327	NN
cord-310847-63gh2tg4	237	5	in	in	IN
cord-310847-63gh2tg4	237	6	transmembrane	transmembrane	NNP
cord-310847-63gh2tg4	237	7	segment	segment	NN
cord-310847-63gh2tg4	237	8	M4	M4	NNP
cord-310847-63gh2tg4	237	9	,	,	,
cord-310847-63gh2tg4	237	10	Glu779	glu779	CD
cord-310847-63gh2tg4	237	11	in	in	IN
cord-310847-63gh2tg4	237	12	M5	M5	NNP
cord-310847-63gh2tg4	237	13	,	,	,
cord-310847-63gh2tg4	237	14	Asp804	asp804	CD
cord-310847-63gh2tg4	237	15	and	and	CC
cord-310847-63gh2tg4	237	16	Asp808	asp808	NN
cord-310847-63gh2tg4	237	17	in	in	IN
cord-310847-63gh2tg4	237	18	M6	M6	NNP
cord-310847-63gh2tg4	237	19	are	be	VBP
cord-310847-63gh2tg4	237	20	essential	essential	JJ
cord-310847-63gh2tg4	237	21	for	for	IN
cord-310847-63gh2tg4	237	22	tight	tight	JJ
cord-310847-63gh2tg4	237	23	binding	binding	NN
cord-310847-63gh2tg4	237	24	of	of	IN
cord-310847-63gh2tg4	237	25	K	k	NN
cord-310847-63gh2tg4	237	26	+	+	CC
cord-310847-63gh2tg4	238	1	and	and	CC
cord-310847-63gh2tg4	238	2	Na	Na	NNP
cord-310847-63gh2tg4	239	1	+	+	CC
cord-310847-63gh2tg4	239	2	,	,	,
cord-310847-63gh2tg4	239	3	whereas	whereas	IN
cord-310847-63gh2tg4	239	4	Asn324	asn324	NN
cord-310847-63gh2tg4	239	5	and	and	CC
cord-310847-63gh2tg4	239	6	Glu327	glu327	NN
cord-310847-63gh2tg4	239	7	in	in	IN
cord-310847-63gh2tg4	239	8	M4	M4	NNP
cord-310847-63gh2tg4	239	9	,	,	,
cord-310847-63gh2tg4	239	10	together	together	RB
cord-310847-63gh2tg4	239	11	with	with	IN
cord-310847-63gh2tg4	239	12	Thr774	thr774	CD
cord-310847-63gh2tg4	239	13	,	,	,
cord-310847-63gh2tg4	239	14	Asn776	asn776	CD
cord-310847-63gh2tg4	239	15	and	and	CC
cord-310847-63gh2tg4	239	16	Glu779	glu779	CD
cord-310847-63gh2tg4	239	17	in	in	IN
cord-310847-63gh2tg4	239	18	the	the	DT
cord-310847-63gh2tg4	239	19	771-YTLTSNIPEITP	771-ytltsnipeitp	CD
cord-310847-63gh2tg4	239	20	motif	motif	NN
cord-310847-63gh2tg4	239	21	of	of	IN
cord-310847-63gh2tg4	239	22	M5	M5	NNS
cord-310847-63gh2tg4	239	23	contribute	contribute	VB
cord-310847-63gh2tg4	239	24	to	to	IN
cord-310847-63gh2tg4	239	25	the	the	DT
cord-310847-63gh2tg4	239	26	Na	Na	NNP
cord-310847-63gh2tg4	240	1	+	+	CC
cord-310847-63gh2tg4	241	1	/	/	NFP
cord-310847-63gh2tg4	241	2	K	k	NN
cord-310847-63gh2tg4	241	3	+	+	CC
cord-310847-63gh2tg4	241	4	selectivity	selectivity	NN
cord-310847-63gh2tg4	241	5	.	.	.
cord-310847-63gh2tg4	242	1	102	102	CD
cord-310847-63gh2tg4	243	1	In	in	IN
cord-310847-63gh2tg4	243	2	the	the	DT
cord-310847-63gh2tg4	243	3	family	family	NN
cord-310847-63gh2tg4	243	4	of	of	IN
cord-310847-63gh2tg4	243	5	thiamin	thiamin	NN
cord-310847-63gh2tg4	243	6	diphosphate	diphosphate	NN
cord-310847-63gh2tg4	243	7	enzymes	enzyme	NNS
cord-310847-63gh2tg4	243	8	,	,	,
cord-310847-63gh2tg4	243	9	a	a	DT
cord-310847-63gh2tg4	243	10	highly	highly	RB
cord-310847-63gh2tg4	243	11	conserved	conserve	VBN
cord-310847-63gh2tg4	243	12	glutamate	glutamate	NN
cord-310847-63gh2tg4	243	13	is	be	VBZ
cord-310847-63gh2tg4	243	14	known	know	VBN
cord-310847-63gh2tg4	243	15	to	to	TO
cord-310847-63gh2tg4	243	16	promote	promote	VB
cord-310847-63gh2tg4	243	17	the	the	DT
cord-310847-63gh2tg4	243	18	C	c	NN
cord-310847-63gh2tg4	243	19	2	2	CD
cord-310847-63gh2tg4	243	20	-H	-H	.
cord-310847-63gh2tg4	243	21	ionization	ionization	NN
cord-310847-63gh2tg4	243	22	and	and	CC
cord-310847-63gh2tg4	243	23	the	the	DT
cord-310847-63gh2tg4	243	24	thiamin	thiamin	NN
cord-310847-63gh2tg4	243	25	diphosphate	diphosphate	NN
cord-310847-63gh2tg4	243	26	activation	activation	NN
cord-310847-63gh2tg4	243	27	.	.	.
cord-310847-63gh2tg4	244	1	103	103	CD
cord-310847-63gh2tg4	245	1	The	the	DT
cord-310847-63gh2tg4	245	2	direct	direct	JJ
cord-310847-63gh2tg4	245	3	catalytic	catalytic	JJ
cord-310847-63gh2tg4	245	4	role	role	NN
cord-310847-63gh2tg4	245	5	of	of	IN
cord-310847-63gh2tg4	245	6	glutamic	glutamic	NN
cord-310847-63gh2tg4	245	7	acid	acid	NN
cord-310847-63gh2tg4	245	8	can	can	MD
cord-310847-63gh2tg4	245	9	be	be	VB
cord-310847-63gh2tg4	245	10	seen	see	VBN
cord-310847-63gh2tg4	245	11	in	in	IN
cord-310847-63gh2tg4	245	12	matrix	matrix	NN
cord-310847-63gh2tg4	245	13	metalloproteinases	metalloproteinase	NNS
cord-310847-63gh2tg4	245	14	,	,	,
cord-310847-63gh2tg4	245	15	which	which	WDT
cord-310847-63gh2tg4	245	16	are	be	VBP
cord-310847-63gh2tg4	245	17	ubiquitous	ubiquitous	JJ
cord-310847-63gh2tg4	245	18	endopeptidases	endopeptidase	NNS
cord-310847-63gh2tg4	245	19	characterized	characterize	VBN
cord-310847-63gh2tg4	245	20	by	by	IN
cord-310847-63gh2tg4	245	21	an	an	DT
cord-310847-63gh2tg4	245	22	active	active	JJ
cord-310847-63gh2tg4	245	23	site	site	NN
cord-310847-63gh2tg4	245	24	where	where	WRB
cord-310847-63gh2tg4	245	25	a	a	DT
cord-310847-63gh2tg4	245	26	Zn	Zn	NNP
cord-310847-63gh2tg4	245	27	2	2	CD
cord-310847-63gh2tg4	245	28	+	+	NN
cord-310847-63gh2tg4	245	29	atom	atom	NN
cord-310847-63gh2tg4	245	30	,	,	,
cord-310847-63gh2tg4	245	31	coordinated	coordinate	VBN
cord-310847-63gh2tg4	245	32	by	by	IN
cord-310847-63gh2tg4	245	33	three	three	CD
cord-310847-63gh2tg4	245	34	histidines	histidine	NNS
cord-310847-63gh2tg4	245	35	,	,	,
cord-310847-63gh2tg4	245	36	plays	play	VBZ
cord-310847-63gh2tg4	245	37	the	the	DT
cord-310847-63gh2tg4	245	38	catalytic	catalytic	JJ
cord-310847-63gh2tg4	245	39	role	role	NN
cord-310847-63gh2tg4	245	40	,	,	,
cord-310847-63gh2tg4	245	41	assisted	assist	VBN
cord-310847-63gh2tg4	245	42	by	by	IN
cord-310847-63gh2tg4	245	43	a	a	DT
cord-310847-63gh2tg4	245	44	glutamic	glutamic	NN
cord-310847-63gh2tg4	245	45	acid	acid	NN
cord-310847-63gh2tg4	245	46	that	that	WDT
cord-310847-63gh2tg4	245	47	acts	act	VBZ
cord-310847-63gh2tg4	245	48	as	as	IN
cord-310847-63gh2tg4	245	49	a	a	DT
cord-310847-63gh2tg4	245	50	general	general	JJ
cord-310847-63gh2tg4	245	51	base	base	NN
cord-310847-63gh2tg4	245	52	.	.	.
cord-310847-63gh2tg4	246	1	104	104	CD
cord-310847-63gh2tg4	247	1	For	for	IN
cord-310847-63gh2tg4	247	2	example	example	NN
cord-310847-63gh2tg4	247	3	,	,	,
cord-310847-63gh2tg4	247	4	one	one	CD
cord-310847-63gh2tg4	247	5	of	of	IN
cord-310847-63gh2tg4	247	6	the	the	DT
cord-310847-63gh2tg4	247	7	wellknown	wellknown	JJ
cord-310847-63gh2tg4	247	8	zinc	zinc	NN
cord-310847-63gh2tg4	247	9	-	-	HYPH
cord-310847-63gh2tg4	247	10	binding	bind	VBG
cord-310847-63gh2tg4	247	11	metalloproteases	metalloprotease	NNS
cord-310847-63gh2tg4	247	12	that	that	WDT
cord-310847-63gh2tg4	247	13	uses	use	VBZ
cord-310847-63gh2tg4	247	14	a	a	DT
cord-310847-63gh2tg4	247	15	glutamic	glutamic	NN
cord-310847-63gh2tg4	247	16	acid	acid	NN
cord-310847-63gh2tg4	247	17	residue	residue	NN
cord-310847-63gh2tg4	247	18	as	as	IN
cord-310847-63gh2tg4	247	19	the	the	DT
cord-310847-63gh2tg4	247	20	fourth	fourth	JJ
cord-310847-63gh2tg4	247	21	ligand	ligand	NN
cord-310847-63gh2tg4	247	22	to	to	TO
cord-310847-63gh2tg4	247	23	coordinate	coordinate	VB
cord-310847-63gh2tg4	247	24	the	the	DT
cord-310847-63gh2tg4	247	25	zinc	zinc	NN
cord-310847-63gh2tg4	247	26	ion	ion	NN
cord-310847-63gh2tg4	247	27	is	be	VBZ
cord-310847-63gh2tg4	247	28	thermolysin	thermolysin	NNP
cord-310847-63gh2tg4	247	29	.	.	.
cord-310847-63gh2tg4	248	1	In	in	IN
cord-310847-63gh2tg4	248	2	thermolysin	thermolysin	NNP
cord-310847-63gh2tg4	248	3	,	,	,
cord-310847-63gh2tg4	248	4	glutamic	glutamic	NN
cord-310847-63gh2tg4	248	5	acid	acid	NN
cord-310847-63gh2tg4	248	6	is	be	VBZ
cord-310847-63gh2tg4	248	7	20	20	CD
cord-310847-63gh2tg4	248	8	amino	amino	NN
cord-310847-63gh2tg4	248	9	acids	acid	NNS
cord-310847-63gh2tg4	248	10	downstream	downstream	RB
cord-310847-63gh2tg4	248	11	from	from	IN
cord-310847-63gh2tg4	248	12	the	the	DT
cord-310847-63gh2tg4	248	13	second	second	JJ
cord-310847-63gh2tg4	248	14	histidine	histidine	NN
cord-310847-63gh2tg4	248	15	in	in	IN
cord-310847-63gh2tg4	248	16	the	the	DT
cord-310847-63gh2tg4	248	17	first	first	JJ
cord-310847-63gh2tg4	248	18	motif	motif	NN
cord-310847-63gh2tg4	248	19	and	and	CC
cord-310847-63gh2tg4	248	20	present	present	JJ
cord-310847-63gh2tg4	248	21	in	in	IN
cord-310847-63gh2tg4	248	22	a	a	DT
cord-310847-63gh2tg4	248	23	small	small	JJ
cord-310847-63gh2tg4	248	24	conserved	conserve	VBN
cord-310847-63gh2tg4	248	25	motif	motif	NN
cord-310847-63gh2tg4	248	26	(	(	-LRB-
cord-310847-63gh2tg4	248	27	NEXXSD	NEXXSD	NNP
cord-310847-63gh2tg4	248	28	)	)	-RRB-
cord-310847-63gh2tg4	248	29	.	.	.
cord-310847-63gh2tg4	249	1	105	105	CD
cord-310847-63gh2tg4	250	1	In	in	IN
cord-310847-63gh2tg4	250	2	the	the	DT
cord-310847-63gh2tg4	250	3	zincin	zincin	NNS
cord-310847-63gh2tg4	250	4	and	and	CC
cord-310847-63gh2tg4	250	5	PDF	PDF	NNP
cord-310847-63gh2tg4	250	6	groups	group	NNS
cord-310847-63gh2tg4	250	7	of	of	IN
cord-310847-63gh2tg4	250	8	metalloproteases	metalloprotease	NNS
cord-310847-63gh2tg4	250	9	,	,	,
cord-310847-63gh2tg4	250	10	the	the	DT
cord-310847-63gh2tg4	250	11	catalytic	catalytic	JJ
cord-310847-63gh2tg4	250	12	zinc	zinc	NN
cord-310847-63gh2tg4	250	13	-	-	HYPH
cord-310847-63gh2tg4	250	14	binding	bind	VBG
cord-310847-63gh2tg4	250	15	site	site	NN
cord-310847-63gh2tg4	250	16	contains	contain	VBZ
cord-310847-63gh2tg4	250	17	the	the	DT
cord-310847-63gh2tg4	250	18	HEXXHXXG	HEXXHXXG	NNP
cord-310847-63gh2tg4	250	19	motif	motif	NN
cord-310847-63gh2tg4	250	20	.	.	.
cord-310847-63gh2tg4	251	1	105	105	CD
cord-310847-63gh2tg4	252	1	Also	also	RB
cord-310847-63gh2tg4	252	2	,	,	,
cord-310847-63gh2tg4	252	3	a	a	DT
cord-310847-63gh2tg4	252	4	glutamic	glutamic	NN
cord-310847-63gh2tg4	252	5	acid	acid	NN
cord-310847-63gh2tg4	252	6	residue	residue	NN
cord-310847-63gh2tg4	252	7	may	may	MD
cord-310847-63gh2tg4	252	8	be	be	VB
cord-310847-63gh2tg4	252	9	catalytically	catalytically	RB
cord-310847-63gh2tg4	252	10	active	active	JJ
cord-310847-63gh2tg4	252	11	in	in	IN
cord-310847-63gh2tg4	252	12	the	the	DT
cord-310847-63gh2tg4	252	13	substrate	substrate	NN
cord-310847-63gh2tg4	252	14	-	-	HYPH
cord-310847-63gh2tg4	252	15	binding	bind	VBG
cord-310847-63gh2tg4	252	16	cleft	cleft	NN
cord-310847-63gh2tg4	252	17	of	of	IN
cord-310847-63gh2tg4	252	18	plant	plant	NN
cord-310847-63gh2tg4	252	19	lysozymes	lysozyme	NNS
cord-310847-63gh2tg4	252	20	.	.	.
cord-310847-63gh2tg4	253	1	106	106	CD
cord-310847-63gh2tg4	254	1	Each	each	DT
cord-310847-63gh2tg4	254	2	enzyme	enzyme	NN
cord-310847-63gh2tg4	254	3	in	in	IN
cord-310847-63gh2tg4	254	4	the	the	DT
cord-310847-63gh2tg4	254	5	α	α	NN
cord-310847-63gh2tg4	254	6	-	-	HYPH
cord-310847-63gh2tg4	254	7	amylase	amylase	NN
cord-310847-63gh2tg4	254	8	family	family	NN
cord-310847-63gh2tg4	254	9	of	of	IN
cord-310847-63gh2tg4	254	10	multidomain	multidomain	NNP
cord-310847-63gh2tg4	254	11	hydrolases	hydrolase	NNS
cord-310847-63gh2tg4	254	12	and	and	CC
cord-310847-63gh2tg4	254	13	transferases	transferase	NNS
cord-310847-63gh2tg4	254	14	has	have	VBZ
cord-310847-63gh2tg4	254	15	one	one	CD
cord-310847-63gh2tg4	254	16	glutamic	glutamic	NN
cord-310847-63gh2tg4	254	17	acid	acid	NN
cord-310847-63gh2tg4	254	18	and	and	CC
cord-310847-63gh2tg4	254	19	two	two	CD
cord-310847-63gh2tg4	254	20	aspartic	aspartic	JJ
cord-310847-63gh2tg4	254	21	acid	acid	NN
cord-310847-63gh2tg4	254	22	residues	residue	NNS
cord-310847-63gh2tg4	254	23	necessary	necessary	JJ
cord-310847-63gh2tg4	254	24	for	for	IN
cord-310847-63gh2tg4	254	25	activity	activity	NN
cord-310847-63gh2tg4	254	26	.	.	.
cord-310847-63gh2tg4	255	1	107	107	CD
cord-310847-63gh2tg4	256	1	The	the	DT
cord-310847-63gh2tg4	256	2	irreversible	irreversible	JJ
cord-310847-63gh2tg4	256	3	dealkylation	dealkylation	NN
cord-310847-63gh2tg4	256	4	reaction	reaction	NN
cord-310847-63gh2tg4	256	5	catalyzed	catalyze	VBN
cord-310847-63gh2tg4	256	6	by	by	IN
cord-310847-63gh2tg4	256	7	the	the	DT
cord-310847-63gh2tg4	256	8	O	O	NNP
cord-310847-63gh2tg4	256	9	6	6	CD
cord-310847-63gh2tg4	256	10	-alkylguanine	-alkylguanine	JJ
cord-310847-63gh2tg4	256	11	-	-	HYPH
cord-310847-63gh2tg4	256	12	DNA	dna	NN
cord-310847-63gh2tg4	256	13	alkyltransferase	alkyltransferase	NN
cord-310847-63gh2tg4	256	14	(	(	-LRB-
cord-310847-63gh2tg4	256	15	AGT	AGT	NNP
cord-310847-63gh2tg4	256	16	)	)	-RRB-
cord-310847-63gh2tg4	256	17	that	that	WDT
cord-310847-63gh2tg4	256	18	directly	directly	RB
cord-310847-63gh2tg4	256	19	repairs	repair	VBZ
cord-310847-63gh2tg4	256	20	alkylation	alkylation	NN
cord-310847-63gh2tg4	256	21	damage	damage	NN
cord-310847-63gh2tg4	256	22	at	at	IN
cord-310847-63gh2tg4	256	23	the	the	DT
cord-310847-63gh2tg4	256	24	O	o	NN
cord-310847-63gh2tg4	256	25	6	6	CD
cord-310847-63gh2tg4	256	26	-position	-position	NN
cord-310847-63gh2tg4	256	27	of	of	IN
cord-310847-63gh2tg4	256	28	guanine	guanine	NN
cord-310847-63gh2tg4	256	29	is	be	VBZ
cord-310847-63gh2tg4	256	30	accomplished	accomplish	VBN
cord-310847-63gh2tg4	256	31	by	by	IN
cord-310847-63gh2tg4	256	32	an	an	DT
cord-310847-63gh2tg4	256	33	active	active	JJ
cord-310847-63gh2tg4	256	34	-	-	HYPH
cord-310847-63gh2tg4	256	35	site	site	NN
cord-310847-63gh2tg4	256	36	cysteine	cysteine	NN
cord-310847-63gh2tg4	256	37	that	that	WDT
cord-310847-63gh2tg4	256	38	participates	participate	VBZ
cord-310847-63gh2tg4	256	39	in	in	IN
cord-310847-63gh2tg4	256	40	a	a	DT
cord-310847-63gh2tg4	256	41	hydrogen	hydrogen	NN
cord-310847-63gh2tg4	256	42	bond	bond	NN
cord-310847-63gh2tg4	256	43	network	network	NN
cord-310847-63gh2tg4	256	44	with	with	IN
cord-310847-63gh2tg4	256	45	invariant	invariant	JJ
cord-310847-63gh2tg4	256	46	histidine	histidine	NN
cord-310847-63gh2tg4	256	47	and	and	CC
cord-310847-63gh2tg4	256	48	glutamic	glutamic	NN
cord-310847-63gh2tg4	256	49	acid	acid	NN
cord-310847-63gh2tg4	256	50	residues	residue	NNS
cord-310847-63gh2tg4	256	51	,	,	,
cord-310847-63gh2tg4	256	52	reminiscent	reminiscent	JJ
cord-310847-63gh2tg4	256	53	of	of	IN
cord-310847-63gh2tg4	256	54	the	the	DT
cord-310847-63gh2tg4	256	55	serine	serine	NN
cord-310847-63gh2tg4	256	56	protease	protease	NN
cord-310847-63gh2tg4	256	57	catalytic	catalytic	JJ
cord-310847-63gh2tg4	256	58	triad	triad	NN
cord-310847-63gh2tg4	256	59	.	.	.
cord-310847-63gh2tg4	257	1	108	108	CD
cord-310847-63gh2tg4	258	1	The	the	DT
cord-310847-63gh2tg4	258	2	spore	spore	NN
cord-310847-63gh2tg4	258	3	germination	germination	NN
cord-310847-63gh2tg4	258	4	protease	protease	NN
cord-310847-63gh2tg4	258	5	(	(	-LRB-
cord-310847-63gh2tg4	258	6	GPR	GPR	NNP
cord-310847-63gh2tg4	258	7	)	)	-RRB-
cord-310847-63gh2tg4	258	8	that	that	WDT
cord-310847-63gh2tg4	258	9	degrades	degrade	VBZ
cord-310847-63gh2tg4	258	10	small	small	JJ
cord-310847-63gh2tg4	258	11	,	,	,
cord-310847-63gh2tg4	258	12	acid	acid	JJ
cord-310847-63gh2tg4	258	13	soluble	soluble	JJ
cord-310847-63gh2tg4	258	14	proteins	protein	NNS
cord-310847-63gh2tg4	258	15	(	(	-LRB-
cord-310847-63gh2tg4	258	16	SASP	SASP	NNP
cord-310847-63gh2tg4	258	17	)	)	-RRB-
cord-310847-63gh2tg4	258	18	protecting	protect	VBG
cord-310847-63gh2tg4	258	19	spore	spore	NN
cord-310847-63gh2tg4	258	20	's	's	POS
cord-310847-63gh2tg4	258	21	DNA	dna	NN
cord-310847-63gh2tg4	258	22	against	against	IN
cord-310847-63gh2tg4	258	23	damage	damage	NN
cord-310847-63gh2tg4	258	24	,	,	,
cord-310847-63gh2tg4	258	25	is	be	VBZ
cord-310847-63gh2tg4	258	26	a	a	DT
cord-310847-63gh2tg4	258	27	structurally	structurally	RB
cord-310847-63gh2tg4	258	28	and	and	CC
cord-310847-63gh2tg4	258	29	functionally	functionally	RB
cord-310847-63gh2tg4	258	30	unique	unique	JJ
cord-310847-63gh2tg4	258	31	protease	protease	NN
cord-310847-63gh2tg4	258	32	that	that	WDT
cord-310847-63gh2tg4	258	33	utilizes	utilize	VBZ
cord-310847-63gh2tg4	258	34	glutamic	glutamic	NN
cord-310847-63gh2tg4	258	35	acid	acid	NN
cord-310847-63gh2tg4	258	36	residue	residue	NN
cord-310847-63gh2tg4	258	37	to	to	TO
cord-310847-63gh2tg4	258	38	catalyze	catalyze	VB
cord-310847-63gh2tg4	258	39	SASP	SASP	NNP
cord-310847-63gh2tg4	258	40	degradation	degradation	NN
cord-310847-63gh2tg4	258	41	.	.	.
cord-310847-63gh2tg4	259	1	109	109	CD
cord-310847-63gh2tg4	260	1	In	in	IN
cord-310847-63gh2tg4	260	2	the	the	DT
cord-310847-63gh2tg4	260	3	hydrolytic	hydrolytic	JJ
cord-310847-63gh2tg4	260	4	aldehyde	aldehyde	NN
cord-310847-63gh2tg4	260	5	dehydrogenases	dehydrogenase	NNS
cord-310847-63gh2tg4	260	6	(	(	-LRB-
cord-310847-63gh2tg4	260	7	ALDHs	ALDHs	NNP
cord-310847-63gh2tg4	260	8	)	)	-RRB-
cord-310847-63gh2tg4	260	9	,	,	,
cord-310847-63gh2tg4	260	10	catalytic	catalytic	JJ
cord-310847-63gh2tg4	260	11	but	but	CC
cord-310847-63gh2tg4	260	12	flexible	flexible	JJ
cord-310847-63gh2tg4	260	13	glutamic	glutamic	NN
cord-310847-63gh2tg4	260	14	acid	acid	NN
cord-310847-63gh2tg4	260	15	residues	residue	NNS
cord-310847-63gh2tg4	260	16	located	locate	VBN
cord-310847-63gh2tg4	260	17	within	within	IN
cord-310847-63gh2tg4	260	18	the	the	DT
cord-310847-63gh2tg4	260	19	active	active	JJ
cord-310847-63gh2tg4	260	20	site	site	NN
cord-310847-63gh2tg4	260	21	serve	serve	VBP
cord-310847-63gh2tg4	260	22	as	as	IN
cord-310847-63gh2tg4	260	23	the	the	DT
cord-310847-63gh2tg4	260	24	general	general	JJ
cord-310847-63gh2tg4	260	25	base	base	NN
cord-310847-63gh2tg4	260	26	that	that	WDT
cord-310847-63gh2tg4	260	27	activates	activate	VBZ
cord-310847-63gh2tg4	260	28	the	the	DT
cord-310847-63gh2tg4	260	29	hydrolytic	hydrolytic	JJ
cord-310847-63gh2tg4	260	30	water	water	NN
cord-310847-63gh2tg4	260	31	molecule	molecule	NN
cord-310847-63gh2tg4	260	32	in	in	IN
cord-310847-63gh2tg4	260	33	the	the	DT
cord-310847-63gh2tg4	260	34	deacylation	deacylation	NN
cord-310847-63gh2tg4	260	35	step	step	NN
cord-310847-63gh2tg4	260	36	.	.	.
cord-310847-63gh2tg4	261	1	110	110	CD
cord-310847-63gh2tg4	261	2	to	to	IN
cord-310847-63gh2tg4	261	3	the	the	DT
cord-310847-63gh2tg4	261	4	net	net	JJ
cord-310847-63gh2tg4	261	5	translocation	translocation	NN
cord-310847-63gh2tg4	261	6	of	of	IN
cord-310847-63gh2tg4	261	7	one	one	CD
cord-310847-63gh2tg4	261	8	electrical	electrical	JJ
cord-310847-63gh2tg4	261	9	charge	charge	NN
cord-310847-63gh2tg4	261	10	across	across	IN
cord-310847-63gh2tg4	261	11	the	the	DT
cord-310847-63gh2tg4	261	12	membrane	membrane	NN
cord-310847-63gh2tg4	261	13	per	per	IN
cord-310847-63gh2tg4	261	14	electron	electron	NN
cord-310847-63gh2tg4	261	15	consumed	consume	VBN
cord-310847-63gh2tg4	261	16	.	.	.
cord-310847-63gh2tg4	262	1	Second	second	RB
cord-310847-63gh2tg4	262	2	,	,	,
cord-310847-63gh2tg4	262	3	an	an	DT
cord-310847-63gh2tg4	262	4	additional	additional	JJ
cord-310847-63gh2tg4	262	5	proton	proton	NN
cord-310847-63gh2tg4	262	6	is	be	VBZ
cord-310847-63gh2tg4	262	7	translocated	translocate	VBN
cord-310847-63gh2tg4	262	8	vectorially	vectorially	RB
cord-310847-63gh2tg4	262	9	across	across	IN
cord-310847-63gh2tg4	262	10	the	the	DT
cord-310847-63gh2tg4	262	11	membrane	membrane	NN
cord-310847-63gh2tg4	262	12	for	for	IN
cord-310847-63gh2tg4	262	13	each	each	DT
cord-310847-63gh2tg4	262	14	electron	electron	NN
cord-310847-63gh2tg4	262	15	consumed	consume	VBN
cord-310847-63gh2tg4	262	16	,	,	,
cord-310847-63gh2tg4	262	17	resulting	result	VBG
cord-310847-63gh2tg4	262	18	in	in	IN
cord-310847-63gh2tg4	262	19	a	a	DT
cord-310847-63gh2tg4	262	20	net	net	JJ
cord-310847-63gh2tg4	262	21	transport	transport	NN
cord-310847-63gh2tg4	262	22	of	of	IN
cord-310847-63gh2tg4	262	23	two	two	CD
cord-310847-63gh2tg4	262	24	electrical	electrical	JJ
cord-310847-63gh2tg4	262	25	charges	charge	NNS
cord-310847-63gh2tg4	262	26	per	per	IN
cord-310847-63gh2tg4	262	27	electron	electron	NN
cord-310847-63gh2tg4	262	28	.	.	.
cord-310847-63gh2tg4	263	1	96	96	CD
cord-310847-63gh2tg4	264	1	The	the	DT
cord-310847-63gh2tg4	264	2	protons	proton	NNS
cord-310847-63gh2tg4	264	3	for	for	IN
cord-310847-63gh2tg4	264	4	the	the	DT
cord-310847-63gh2tg4	264	5	chemical	chemical	JJ
cord-310847-63gh2tg4	264	6	reaction	reaction	NN
cord-310847-63gh2tg4	264	7	are	be	VBP
cord-310847-63gh2tg4	264	8	extracted	extract	VBN
cord-310847-63gh2tg4	264	9	from	from	IN
cord-310847-63gh2tg4	264	10	the	the	DT
cord-310847-63gh2tg4	264	11	N	n	CD
cord-310847-63gh2tg4	264	12	-	-	HYPH
cord-310847-63gh2tg4	264	13	side	side	NN
cord-310847-63gh2tg4	264	14	of	of	IN
cord-310847-63gh2tg4	264	15	the	the	DT
cord-310847-63gh2tg4	264	16	membrane	membrane	NN
cord-310847-63gh2tg4	264	17	via	via	IN
cord-310847-63gh2tg4	264	18	two	two	CD
cord-310847-63gh2tg4	264	19	proton	proton	NN
cord-310847-63gh2tg4	264	20	pathways	pathway	NNS
cord-310847-63gh2tg4	264	21	,	,	,
cord-310847-63gh2tg4	264	22	the	the	DT
cord-310847-63gh2tg4	264	23	D	d	NN
cord-310847-63gh2tg4	264	24	-	-	:
cord-310847-63gh2tg4	264	25	and	and	CC
cord-310847-63gh2tg4	264	26	K	K	NNP
cord-310847-63gh2tg4	264	27	-	-	HYPH
cord-310847-63gh2tg4	264	28	channels	channel	NNS
cord-310847-63gh2tg4	264	29	.	.	.
cord-310847-63gh2tg4	265	1	The	the	DT
cord-310847-63gh2tg4	265	2	D	d	NN
cord-310847-63gh2tg4	265	3	-	-	HYPH
cord-310847-63gh2tg4	265	4	channel	channel	NN
cord-310847-63gh2tg4	265	5	starts	start	NNS
cord-310847-63gh2tg4	265	6	at	at	IN
cord-310847-63gh2tg4	265	7	a	a	DT
cord-310847-63gh2tg4	265	8	highly	highly	RB
cord-310847-63gh2tg4	265	9	conserved	conserved	JJ
cord-310847-63gh2tg4	265	10	residue	residue	NN
cord-310847-63gh2tg4	265	11	,	,	,
cord-310847-63gh2tg4	265	12	Asp	Asp	NNP
cord-310847-63gh2tg4	265	13	91	91	CD
cord-310847-63gh2tg4	265	14	(	(	-LRB-
cord-310847-63gh2tg4	265	15	bovine	bovine	JJ
cord-310847-63gh2tg4	265	16	numbering	numbering	NN
cord-310847-63gh2tg4	265	17	;	;	,
cord-310847-63gh2tg4	265	18	subunit	subunit	NN
cord-310847-63gh2tg4	265	19	I	I	NNP
cord-310847-63gh2tg4	265	20	)	)	-RRB-
cord-310847-63gh2tg4	265	21	near	near	IN
cord-310847-63gh2tg4	265	22	the	the	DT
cord-310847-63gh2tg4	265	23	N	n	CD
cord-310847-63gh2tg4	265	24	side	side	NN
cord-310847-63gh2tg4	265	25	,	,	,
cord-310847-63gh2tg4	265	26	and	and	CC
cord-310847-63gh2tg4	265	27	continues	continue	VBZ
cord-310847-63gh2tg4	265	28	to	to	IN
cord-310847-63gh2tg4	265	29	another	another	DT
cord-310847-63gh2tg4	265	30	highly	highly	RB
cord-310847-63gh2tg4	265	31	conserved	conserved	JJ
cord-310847-63gh2tg4	265	32	residue	residue	NN
cord-310847-63gh2tg4	265	33	Glu242	Glu242	NFP
cord-310847-63gh2tg4	265	34	that	that	WDT
cord-310847-63gh2tg4	265	35	donates	donate	VBZ
cord-310847-63gh2tg4	265	36	protons	proton	NNS
cord-310847-63gh2tg4	265	37	to	to	IN
cord-310847-63gh2tg4	265	38	the	the	DT
cord-310847-63gh2tg4	265	39	BNC	bnc	NN
cord-310847-63gh2tg4	265	40	,	,	,
cord-310847-63gh2tg4	265	41	whereas	whereas	IN
cord-310847-63gh2tg4	265	42	the	the	DT
cord-310847-63gh2tg4	265	43	key	key	JJ
cord-310847-63gh2tg4	265	44	residue	residue	NN
cord-310847-63gh2tg4	265	45	in	in	IN
cord-310847-63gh2tg4	265	46	the	the	DT
cord-310847-63gh2tg4	265	47	K	K	NNP
cord-310847-63gh2tg4	265	48	-	-	HYPH
cord-310847-63gh2tg4	265	49	channel	channel	NNP
cord-310847-63gh2tg4	265	50	is	be	VBZ
cord-310847-63gh2tg4	265	51	a	a	DT
cord-310847-63gh2tg4	265	52	highly	highly	RB
cord-310847-63gh2tg4	265	53	conserved	conserved	JJ
cord-310847-63gh2tg4	265	54	lysine	lysine	NN
cord-310847-63gh2tg4	265	55	(	(	-LRB-
cord-310847-63gh2tg4	265	56	K319	k319	CD
cord-310847-63gh2tg4	265	57	)	)	-RRB-
cord-310847-63gh2tg4	265	58	.	.	.
cord-310847-63gh2tg4	266	1	95	95	CD
cord-310847-63gh2tg4	267	1	The	the	DT
cord-310847-63gh2tg4	267	2	D	d	NN
cord-310847-63gh2tg4	267	3	-	-	HYPH
cord-310847-63gh2tg4	267	4	channel	channel	NN
cord-310847-63gh2tg4	267	5	is	be	VBZ
cord-310847-63gh2tg4	267	6	responsible	responsible	JJ
cord-310847-63gh2tg4	267	7	for	for	IN
cord-310847-63gh2tg4	267	8	the	the	DT
cord-310847-63gh2tg4	267	9	delivery	delivery	NN
cord-310847-63gh2tg4	267	10	of	of	IN
cord-310847-63gh2tg4	267	11	four	four	CD
cord-310847-63gh2tg4	267	12	"	"	``
cord-310847-63gh2tg4	267	13	pump	pump	NN
cord-310847-63gh2tg4	267	14	"	"	''
cord-310847-63gh2tg4	267	15	protons	proton	NNS
cord-310847-63gh2tg4	267	16	that	that	WDT
cord-310847-63gh2tg4	267	17	are	be	VBP
cord-310847-63gh2tg4	267	18	first	first	RB
cord-310847-63gh2tg4	267	19	transferred	transfer	VBN
cord-310847-63gh2tg4	267	20	from	from	IN
cord-310847-63gh2tg4	267	21	Glu242	glu242	CD
cord-310847-63gh2tg4	267	22	to	to	IN
cord-310847-63gh2tg4	267	23	a	a	DT
cord-310847-63gh2tg4	267	24	"	"	``
cord-310847-63gh2tg4	267	25	loading	loading	NN
cord-310847-63gh2tg4	267	26	"	"	''
cord-310847-63gh2tg4	267	27	site	site	NN
cord-310847-63gh2tg4	267	28	above	above	IN
cord-310847-63gh2tg4	267	29	the	the	DT
cord-310847-63gh2tg4	267	30	BNC	BNC	NNP
cord-310847-63gh2tg4	267	31	and	and	CC
cord-310847-63gh2tg4	267	32	then	then	RB
cord-310847-63gh2tg4	267	33	delivered	deliver	VBD
cord-310847-63gh2tg4	267	34	to	to	IN
cord-310847-63gh2tg4	267	35	the	the	DT
cord-310847-63gh2tg4	267	36	P	p	NN
cord-310847-63gh2tg4	267	37	side	side	NN
cord-310847-63gh2tg4	267	38	via	via	IN
cord-310847-63gh2tg4	267	39	a	a	DT
cord-310847-63gh2tg4	267	40	proton	proton	NN
cord-310847-63gh2tg4	267	41	-	-	HYPH
cord-310847-63gh2tg4	267	42	exit	exit	NN
cord-310847-63gh2tg4	267	43	channel	channel	NN
cord-310847-63gh2tg4	267	44	.	.	.
cord-310847-63gh2tg4	268	1	The	the	DT
cord-310847-63gh2tg4	268	2	mystery	mystery	NN
cord-310847-63gh2tg4	268	3	of	of	IN
cord-310847-63gh2tg4	268	4	this	this	DT
cord-310847-63gh2tg4	268	5	mechanism	mechanism	NN
cord-310847-63gh2tg4	268	6	is	be	VBZ
cord-310847-63gh2tg4	268	7	in	in	IN
cord-310847-63gh2tg4	268	8	the	the	DT
cord-310847-63gh2tg4	268	9	ability	ability	NN
cord-310847-63gh2tg4	268	10	of	of	IN
cord-310847-63gh2tg4	268	11	Glu242	glu242	CD
cord-310847-63gh2tg4	268	12	located	locate	VBN
cord-310847-63gh2tg4	268	13	at	at	IN
cord-310847-63gh2tg4	268	14	the	the	DT
cord-310847-63gh2tg4	268	15	end	end	NN
cord-310847-63gh2tg4	268	16	of	of	IN
cord-310847-63gh2tg4	268	17	the	the	DT
cord-310847-63gh2tg4	268	18	D	d	NN
cord-310847-63gh2tg4	268	19	-	-	HYPH
cord-310847-63gh2tg4	268	20	channel	channel	NN
cord-310847-63gh2tg4	268	21	to	to	TO
cord-310847-63gh2tg4	268	22	somehow	somehow	RB
cord-310847-63gh2tg4	268	23	sort	sort	VB
cord-310847-63gh2tg4	268	24	"	"	``
cord-310847-63gh2tg4	268	25	pump	pump	NN
cord-310847-63gh2tg4	268	26	"	"	''
cord-310847-63gh2tg4	268	27	protons	proton	NNS
cord-310847-63gh2tg4	268	28	from	from	IN
cord-310847-63gh2tg4	268	29	"	"	``
cord-310847-63gh2tg4	268	30	chemical	chemical	JJ
cord-310847-63gh2tg4	268	31	"	"	''
cord-310847-63gh2tg4	268	32	protons	proton	NNS
cord-310847-63gh2tg4	268	33	.	.	.
cord-310847-63gh2tg4	269	1	95	95	CD
cord-310847-63gh2tg4	270	1	To	to	TO
cord-310847-63gh2tg4	270	2	explain	explain	VB
cord-310847-63gh2tg4	270	3	this	this	DT
cord-310847-63gh2tg4	270	4	behavior	behavior	NN
cord-310847-63gh2tg4	270	5	,	,	,
cord-310847-63gh2tg4	270	6	the	the	DT
cord-310847-63gh2tg4	270	7	glutamate	glutamate	NN
cord-310847-63gh2tg4	270	8	valve	valve	NN
cord-310847-63gh2tg4	270	9	model	model	NN
cord-310847-63gh2tg4	270	10	has	have	VBZ
cord-310847-63gh2tg4	270	11	been	be	VBN
cord-310847-63gh2tg4	270	12	proposed	propose	VBN
cord-310847-63gh2tg4	270	13	according	accord	VBG
cord-310847-63gh2tg4	270	14	to	to	IN
cord-310847-63gh2tg4	270	15	which	which	WDT
cord-310847-63gh2tg4	270	16	the	the	DT
cord-310847-63gh2tg4	270	17	side	side	NN
cord-310847-63gh2tg4	270	18	chain	chain	NN
cord-310847-63gh2tg4	270	19	of	of	IN
cord-310847-63gh2tg4	270	20	Glu242	glu242	CD
cord-310847-63gh2tg4	270	21	shuttles	shuttle	NNS
cord-310847-63gh2tg4	270	22	between	between	IN
cord-310847-63gh2tg4	270	23	a	a	DT
cord-310847-63gh2tg4	270	24	state	state	NN
cord-310847-63gh2tg4	270	25	protonically	protonically	RB
cord-310847-63gh2tg4	270	26	connected	connect	VBN
cord-310847-63gh2tg4	270	27	to	to	IN
cord-310847-63gh2tg4	270	28	the	the	DT
cord-310847-63gh2tg4	270	29	D	D	NNP
cord-310847-63gh2tg4	270	30	channel	channel	NN
cord-310847-63gh2tg4	270	31	,	,	,
cord-310847-63gh2tg4	270	32	and	and	CC
cord-310847-63gh2tg4	270	33	a	a	DT
cord-310847-63gh2tg4	270	34	state	state	NN
cord-310847-63gh2tg4	270	35	connected	connect	VBN
cord-310847-63gh2tg4	270	36	to	to	IN
cord-310847-63gh2tg4	270	37	the	the	DT
cord-310847-63gh2tg4	270	38	BNC	bnc	NN
cord-310847-63gh2tg4	270	39	and	and	CC
cord-310847-63gh2tg4	270	40	the	the	DT
cord-310847-63gh2tg4	270	41	pump	pump	NN
cord-310847-63gh2tg4	270	42	site	site	NN
cord-310847-63gh2tg4	270	43	.	.	.
cord-310847-63gh2tg4	271	1	97	97	CD
cord-310847-63gh2tg4	272	1	In	in	IN
cord-310847-63gh2tg4	272	2	this	this	DT
cord-310847-63gh2tg4	272	3	proton	proton	NN
cord-310847-63gh2tg4	272	4	valve	valve	NN
cord-310847-63gh2tg4	272	5	model	model	NN
cord-310847-63gh2tg4	272	6	,	,	,
cord-310847-63gh2tg4	272	7	the	the	DT
cord-310847-63gh2tg4	272	8	Glu242	glu242	CD
cord-310847-63gh2tg4	272	9	motion	motion	NN
cord-310847-63gh2tg4	272	10	depends	depend	VBZ
cord-310847-63gh2tg4	272	11	on	on	IN
cord-310847-63gh2tg4	272	12	its	-PRON-	PRP$
cord-310847-63gh2tg4	272	13	protonation	protonation	JJ
cord-310847-63gh2tg4	272	14	state	state	NN
cord-310847-63gh2tg4	272	15	,	,	,
cord-310847-63gh2tg4	272	16	where	where	WRB
cord-310847-63gh2tg4	272	17	the	the	DT
cord-310847-63gh2tg4	272	18	unprotonated	unprotonated	JJ
cord-310847-63gh2tg4	272	19	residue	residue	NN
cord-310847-63gh2tg4	272	20	remains	remain	VBZ
cord-310847-63gh2tg4	272	21	predominantly	predominantly	RB
cord-310847-63gh2tg4	272	22	in	in	IN
cord-310847-63gh2tg4	272	23	a	a	DT
cord-310847-63gh2tg4	272	24	"	"	``
cord-310847-63gh2tg4	272	25	down	down	JJ
cord-310847-63gh2tg4	272	26	"	"	''
cord-310847-63gh2tg4	272	27	conformation	conformation	NN
cord-310847-63gh2tg4	272	28	,	,	,
cord-310847-63gh2tg4	272	29	pointing	point	VBG
cord-310847-63gh2tg4	272	30	toward	toward	IN
cord-310847-63gh2tg4	272	31	the	the	DT
cord-310847-63gh2tg4	272	32	N	n	CD
cord-310847-63gh2tg4	272	33	side	side	NN
cord-310847-63gh2tg4	272	34	,	,	,
cord-310847-63gh2tg4	272	35	and	and	CC
cord-310847-63gh2tg4	272	36	therefore	therefore	RB
cord-310847-63gh2tg4	272	37	facilitating	facilitate	VBG
cord-310847-63gh2tg4	272	38	the	the	DT
cord-310847-63gh2tg4	272	39	uptake	uptake	NN
cord-310847-63gh2tg4	272	40	of	of	IN
cord-310847-63gh2tg4	272	41	a	a	DT
cord-310847-63gh2tg4	272	42	proton	proton	NN
cord-310847-63gh2tg4	272	43	,	,	,
cord-310847-63gh2tg4	272	44	whereas	whereas	IN
cord-310847-63gh2tg4	272	45	protonation	protonation	NN
cord-310847-63gh2tg4	272	46	shifts	shift	VBZ
cord-310847-63gh2tg4	272	47	the	the	DT
cord-310847-63gh2tg4	272	48	Glu242	glu242	CD
cord-310847-63gh2tg4	272	49	to	to	IN
cord-310847-63gh2tg4	272	50	the	the	DT
cord-310847-63gh2tg4	272	51	"	"	``
cord-310847-63gh2tg4	272	52	up	up	JJ
cord-310847-63gh2tg4	272	53	"	"	''
cord-310847-63gh2tg4	272	54	conformation	conformation	NN
cord-310847-63gh2tg4	272	55	,	,	,
cord-310847-63gh2tg4	272	56	where	where	WRB
cord-310847-63gh2tg4	272	57	the	the	DT
cord-310847-63gh2tg4	272	58	side	side	NN
cord-310847-63gh2tg4	272	59	chain	chain	NN
cord-310847-63gh2tg4	272	60	of	of	IN
cord-310847-63gh2tg4	272	61	this	this	DT
cord-310847-63gh2tg4	272	62	important	important	JJ
cord-310847-63gh2tg4	272	63	residue	residue	NN
cord-310847-63gh2tg4	272	64	is	be	VBZ
cord-310847-63gh2tg4	272	65	swung	swing	VBN
cord-310847-63gh2tg4	272	66	toward	toward	IN
cord-310847-63gh2tg4	272	67	the	the	DT
cord-310847-63gh2tg4	272	68	P	p	NN
cord-310847-63gh2tg4	272	69	side	side	NN
cord-310847-63gh2tg4	272	70	by	by	IN
cord-310847-63gh2tg4	272	71	~4	~4	CD
cord-310847-63gh2tg4	272	72	Å.	Å.	NNP
cord-310847-63gh2tg4	272	73	97	97	CD
cord-310847-63gh2tg4	272	74	Glutamic	glutamic	NN
cord-310847-63gh2tg4	272	75	acid	acid	NN
cord-310847-63gh2tg4	272	76	in	in	IN
cord-310847-63gh2tg4	272	77	the	the	DT
cord-310847-63gh2tg4	272	78	active	active	JJ
cord-310847-63gh2tg4	272	79	sites	site	NNS
cord-310847-63gh2tg4	272	80	of	of	IN
cord-310847-63gh2tg4	272	81	enzymes	enzyme	NNS
cord-310847-63gh2tg4	272	82	.	.	.
cord-310847-63gh2tg4	273	1	In	in	IN
cord-310847-63gh2tg4	273	2	addition	addition	NN
cord-310847-63gh2tg4	273	3	to	to	TO
cord-310847-63gh2tg4	273	4	serve	serve	VB
cord-310847-63gh2tg4	273	5	multiple	multiple	JJ
cord-310847-63gh2tg4	273	6	structural	structural	JJ
cord-310847-63gh2tg4	273	7	roles	role	NNS
cord-310847-63gh2tg4	273	8	and	and	CC
cord-310847-63gh2tg4	273	9	being	be	VBG
cord-310847-63gh2tg4	273	10	involved	involve	VBN
cord-310847-63gh2tg4	273	11	in	in	IN
cord-310847-63gh2tg4	273	12	regulation	regulation	NN
cord-310847-63gh2tg4	273	13	of	of	IN
cord-310847-63gh2tg4	273	14	various	various	JJ
cord-310847-63gh2tg4	273	15	channels	channel	NNS
cord-310847-63gh2tg4	273	16	,	,	,
cord-310847-63gh2tg4	273	17	glutamic	glutamic	NN
cord-310847-63gh2tg4	273	18	acid	acid	NN
cord-310847-63gh2tg4	273	19	residues	residue	NNS
cord-310847-63gh2tg4	273	20	,	,	,
cord-310847-63gh2tg4	273	21	being	be	VBG
cord-310847-63gh2tg4	273	22	positioned	position	VBN
cord-310847-63gh2tg4	273	23	within	within	IN
cord-310847-63gh2tg4	273	24	or	or	CC
cord-310847-63gh2tg4	273	25	in	in	IN
cord-310847-63gh2tg4	273	26	the	the	DT
cord-310847-63gh2tg4	273	27	close	close	JJ
cord-310847-63gh2tg4	273	28	proximity	proximity	NN
cord-310847-63gh2tg4	273	29	to	to	IN
cord-310847-63gh2tg4	273	30	the	the	DT
cord-310847-63gh2tg4	273	31	active	active	JJ
cord-310847-63gh2tg4	273	32	sites	site	NNS
cord-310847-63gh2tg4	273	33	,	,	,
cord-310847-63gh2tg4	273	34	might	may	MD
cord-310847-63gh2tg4	273	35	have	have	VB
cord-310847-63gh2tg4	273	36	roles	role	NNS
cord-310847-63gh2tg4	273	37	in	in	IN
cord-310847-63gh2tg4	273	38	the	the	DT
cord-310847-63gh2tg4	273	39	catalytic	catalytic	JJ
cord-310847-63gh2tg4	273	40	activities	activity	NNS
cord-310847-63gh2tg4	273	41	of	of	IN
cord-310847-63gh2tg4	273	42	various	various	JJ
cord-310847-63gh2tg4	273	43	enzymes	enzyme	NNS
cord-310847-63gh2tg4	273	44	.	.	.
cord-310847-63gh2tg4	274	1	One	one	CD
cord-310847-63gh2tg4	274	2	of	of	IN
cord-310847-63gh2tg4	274	3	the	the	DT
cord-310847-63gh2tg4	274	4	illustrative	illustrative	JJ
cord-310847-63gh2tg4	274	5	examples	example	NNS
cord-310847-63gh2tg4	274	6	of	of	IN
cord-310847-63gh2tg4	274	7	the	the	DT
cord-310847-63gh2tg4	274	8	functional	functional	JJ
cord-310847-63gh2tg4	274	9	roles	role	NNS
cord-310847-63gh2tg4	274	10	of	of	IN
cord-310847-63gh2tg4	274	11	glutamic	glutamic	NN
cord-310847-63gh2tg4	274	12	acid	acid	NN
cord-310847-63gh2tg4	274	13	can	can	MD
cord-310847-63gh2tg4	274	14	be	be	VB
cord-310847-63gh2tg4	274	15	found	find	VBN
cord-310847-63gh2tg4	274	16	in	in	IN
cord-310847-63gh2tg4	274	17	bacterial	bacterial	JJ
cord-310847-63gh2tg4	274	18	nitric	nitric	NN
cord-310847-63gh2tg4	274	19	oxide	oxide	NN
cord-310847-63gh2tg4	274	20	reductase	reductase	NN
cord-310847-63gh2tg4	274	21	(	(	-LRB-
cord-310847-63gh2tg4	275	1	NOR	nor	CC
cord-310847-63gh2tg4	275	2	)	)	-RRB-
cord-310847-63gh2tg4	275	3	,	,	,
cord-310847-63gh2tg4	275	4	which	which	WDT
cord-310847-63gh2tg4	275	5	is	be	VBZ
cord-310847-63gh2tg4	275	6	a	a	DT
cord-310847-63gh2tg4	275	7	membraneintegrated	membraneintegrate	VBN
cord-310847-63gh2tg4	275	8	enzyme	enzyme	NN
cord-310847-63gh2tg4	275	9	that	that	WDT
cord-310847-63gh2tg4	275	10	catalyzes	catalyze	VBZ
cord-310847-63gh2tg4	275	11	the	the	DT
cord-310847-63gh2tg4	275	12	reduction	reduction	NN
cord-310847-63gh2tg4	275	13	of	of	IN
cord-310847-63gh2tg4	275	14	nitric	nitric	NN
cord-310847-63gh2tg4	275	15	oxide	oxide	NN
cord-310847-63gh2tg4	276	1	NO	no	RB
cord-310847-63gh2tg4	276	2	to	to	IN
cord-310847-63gh2tg4	276	3	nitrous	nitrous	JJ
cord-310847-63gh2tg4	276	4	oxide	oxide	NN
cord-310847-63gh2tg4	276	5	N	n	CD
cord-310847-63gh2tg4	276	6	2	2	CD
cord-310847-63gh2tg4	276	7	O	o	NN
cord-310847-63gh2tg4	276	8	using	use	VBG
cord-310847-63gh2tg4	276	9	a	a	DT
cord-310847-63gh2tg4	276	10	type	type	NN
cord-310847-63gh2tg4	276	11	of	of	IN
cord-310847-63gh2tg4	276	12	anaerobic	anaerobic	JJ
cord-310847-63gh2tg4	276	13	respiration	respiration	NN
cord-310847-63gh2tg4	276	14	where	where	WRB
cord-310847-63gh2tg4	276	15	cytotoxic	cytotoxic	JJ
cord-310847-63gh2tg4	276	16	NO	no	NN
cord-310847-63gh2tg4	276	17	is	be	VBZ
cord-310847-63gh2tg4	276	18	immediately	immediately	RB
cord-310847-63gh2tg4	276	19	decomposed	decompose	VBN
cord-310847-63gh2tg4	276	20	after	after	IN
cord-310847-63gh2tg4	276	21	its	-PRON-	PRP$
cord-310847-63gh2tg4	276	22	production	production	NN
cord-310847-63gh2tg4	276	23	from	from	IN
cord-310847-63gh2tg4	276	24	nitrite	nitrite	NN
cord-310847-63gh2tg4	276	25	NO	no	DT
cord-310847-63gh2tg4	276	26	2	2	CD
cord-310847-63gh2tg4	276	27	−	−	NN
cord-310847-63gh2tg4	276	28	via	via	IN
cord-310847-63gh2tg4	276	29	the	the	DT
cord-310847-63gh2tg4	276	30	nitrite	nitrite	NN
cord-310847-63gh2tg4	276	31	reductase	reductase	NN
cord-310847-63gh2tg4	276	32	-	-	HYPH
cord-310847-63gh2tg4	276	33	catalyzed	catalyze	VBN
cord-310847-63gh2tg4	276	34	reaction	reaction	NN
cord-310847-63gh2tg4	276	35	.	.	.
cord-310847-63gh2tg4	277	1	[	[	-LRB-
cord-310847-63gh2tg4	277	2	98	98	CD
cord-310847-63gh2tg4	277	3	]	]	-RRB-
cord-310847-63gh2tg4	277	4	[	[	-LRB-
cord-310847-63gh2tg4	277	5	99	99	CD
cord-310847-63gh2tg4	277	6	]	]	-RRB-
cord-310847-63gh2tg4	278	1	[	[	-LRB-
cord-310847-63gh2tg4	278	2	100	100	CD
cord-310847-63gh2tg4	278	3	]	]	-RRB-
cord-310847-63gh2tg4	279	1	Three	three	CD
cord-310847-63gh2tg4	279	2	different	different	JJ
cord-310847-63gh2tg4	279	3	NOR	nor	CC
cord-310847-63gh2tg4	279	4	types	type	NNS
cord-310847-63gh2tg4	279	5	are	be	VBP
cord-310847-63gh2tg4	279	6	found	find	VBN
cord-310847-63gh2tg4	279	7	in	in	IN
cord-310847-63gh2tg4	279	8	bacteria	bacteria	NNS
cord-310847-63gh2tg4	279	9	,	,	,
cord-310847-63gh2tg4	279	10	with	with	IN
cord-310847-63gh2tg4	279	11	the	the	DT
cord-310847-63gh2tg4	279	12	cytochrome	cytochrome	NN
cord-310847-63gh2tg4	279	13	c	c	NN
cord-310847-63gh2tg4	279	14	dependent	dependent	JJ
cord-310847-63gh2tg4	279	15	NOR	NOR	.
cord-310847-63gh2tg4	280	1	(	(	-LRB-
cord-310847-63gh2tg4	280	2	cNOR	cnor	LS
cord-310847-63gh2tg4	280	3	)	)	-RRB-
cord-310847-63gh2tg4	280	4	that	that	WDT
cord-310847-63gh2tg4	280	5	consists	consist	VBZ
cord-310847-63gh2tg4	280	6	of	of	IN
cord-310847-63gh2tg4	280	7	two	two	CD
cord-310847-63gh2tg4	280	8	subunits	subunit	NNS
cord-310847-63gh2tg4	280	9	,	,	,
cord-310847-63gh2tg4	280	10	NorB	NorB	NNP
cord-310847-63gh2tg4	280	11	and	and	CC
cord-310847-63gh2tg4	280	12	NorC	NorC	NNP
cord-310847-63gh2tg4	280	13	,	,	,
cord-310847-63gh2tg4	280	14	being	be	VBG
cord-310847-63gh2tg4	280	15	the	the	DT
cord-310847-63gh2tg4	280	16	most	most	RBS
cord-310847-63gh2tg4	280	17	extensively	extensively	RB
cord-310847-63gh2tg4	280	18	studied	study	VBN
cord-310847-63gh2tg4	280	19	enzyme	enzyme	NN
cord-310847-63gh2tg4	280	20	.	.	.
cord-310847-63gh2tg4	281	1	Precise	precise	JJ
cord-310847-63gh2tg4	281	2	description	description	NN
cord-310847-63gh2tg4	281	3	of	of	IN
cord-310847-63gh2tg4	281	4	the	the	DT
cord-310847-63gh2tg4	281	5	complex	complex	JJ
cord-310847-63gh2tg4	281	6	catalytic	catalytic	JJ
cord-310847-63gh2tg4	281	7	mechanism	mechanism	NN
cord-310847-63gh2tg4	281	8	of	of	IN
cord-310847-63gh2tg4	281	9	this	this	DT
cord-310847-63gh2tg4	281	10	important	important	JJ
cord-310847-63gh2tg4	281	11	enzyme	enzyme	NN
cord-310847-63gh2tg4	281	12	is	be	VBZ
cord-310847-63gh2tg4	281	13	outside	outside	IN
cord-310847-63gh2tg4	281	14	the	the	DT
cord-310847-63gh2tg4	281	15	scopes	scope	NNS
cord-310847-63gh2tg4	281	16	of	of	IN
cord-310847-63gh2tg4	281	17	this	this	DT
cord-310847-63gh2tg4	281	18	review	review	NN
cord-310847-63gh2tg4	281	19	,	,	,
cord-310847-63gh2tg4	281	20	and	and	CC
cord-310847-63gh2tg4	281	21	therefore	therefore	RB
cord-310847-63gh2tg4	281	22	only	only	RB
cord-310847-63gh2tg4	281	23	a	a	DT
cord-310847-63gh2tg4	281	24	small	small	JJ
cord-310847-63gh2tg4	281	25	piece	piece	NN
cord-310847-63gh2tg4	281	26	of	of	IN
cord-310847-63gh2tg4	281	27	the	the	DT
cord-310847-63gh2tg4	281	28	entire	entire	JJ
cord-310847-63gh2tg4	281	29	picture	picture	NN
cord-310847-63gh2tg4	281	30	,	,	,
cord-310847-63gh2tg4	281	31	where	where	WRB
cord-310847-63gh2tg4	281	32	the	the	DT
cord-310847-63gh2tg4	281	33	roles	role	NNS
cord-310847-63gh2tg4	281	34	of	of	IN
cord-310847-63gh2tg4	281	35	glutamic	glutamic	NN
cord-310847-63gh2tg4	281	36	acid	acid	NN
cord-310847-63gh2tg4	281	37	are	be	VBP
cord-310847-63gh2tg4	281	38	emphasized	emphasize	VBN
cord-310847-63gh2tg4	281	39	,	,	,
cord-310847-63gh2tg4	281	40	is	be	VBZ
cord-310847-63gh2tg4	281	41	briefly	briefly	RB
cord-310847-63gh2tg4	281	42	described	describe	VBN
cord-310847-63gh2tg4	281	43	below	below	RB
cord-310847-63gh2tg4	281	44	.	.	.
cord-310847-63gh2tg4	282	1	The	the	DT
cord-310847-63gh2tg4	282	2	characteristic	characteristic	JJ
cord-310847-63gh2tg4	282	3	feature	feature	NN
cord-310847-63gh2tg4	282	4	of	of	IN
cord-310847-63gh2tg4	282	5	cNORs	cNORs	NNP
cord-310847-63gh2tg4	282	6	is	be	VBZ
cord-310847-63gh2tg4	282	7	the	the	DT
cord-310847-63gh2tg4	282	8	presence	presence	NN
cord-310847-63gh2tg4	282	9	of	of	IN
cord-310847-63gh2tg4	282	10	five	five	CD
cord-310847-63gh2tg4	282	11	conserved	conserved	JJ
cord-310847-63gh2tg4	282	12	glutamic	glutamic	NN
cord-310847-63gh2tg4	282	13	acid	acid	NN
cord-310847-63gh2tg4	282	14	residues	residue	NNS
cord-310847-63gh2tg4	282	15	(	(	-LRB-
cord-310847-63gh2tg4	282	16	Glu135	Glu135	NNS
cord-310847-63gh2tg4	282	17	,	,	,
cord-310847-63gh2tg4	282	18	Glu138	glu138	ADD
cord-310847-63gh2tg4	282	19	,	,	,
cord-310847-63gh2tg4	282	20	Glu211	glu211	CD
cord-310847-63gh2tg4	282	21	,	,	,
cord-310847-63gh2tg4	282	22	Glu215	Glu215	,
cord-310847-63gh2tg4	282	23	and	and	CC
cord-310847-63gh2tg4	282	24	Glu280	glu280	CD
cord-310847-63gh2tg4	282	25	in	in	IN
cord-310847-63gh2tg4	282	26	P.	P.	NNP
cord-310847-63gh2tg4	282	27	aeruginosa	aeruginosa	NNP
cord-310847-63gh2tg4	282	28	cNOR	cNOR	NNP
cord-310847-63gh2tg4	282	29	)	)	-RRB-
cord-310847-63gh2tg4	282	30	within	within	IN
cord-310847-63gh2tg4	282	31	the	the	DT
cord-310847-63gh2tg4	282	32	NorB	NorB	NNP
cord-310847-63gh2tg4	282	33	subunit	subunit	NN
cord-310847-63gh2tg4	282	34	consisting	consist	VBG
cord-310847-63gh2tg4	282	35	of	of	IN
cord-310847-63gh2tg4	282	36	12	12	CD
cord-310847-63gh2tg4	282	37	trans	trans	NN
cord-310847-63gh2tg4	282	38	-	-	NN
cord-310847-63gh2tg4	282	39	membrane	membrane	NN
cord-310847-63gh2tg4	282	40	helices	helix	NNS
cord-310847-63gh2tg4	282	41	and	and	CC
cord-310847-63gh2tg4	282	42	containing	contain	VBG
cord-310847-63gh2tg4	282	43	the	the	DT
cord-310847-63gh2tg4	282	44	heme	heme	NN
cord-310847-63gh2tg4	282	45	b	b	NN
cord-310847-63gh2tg4	282	46	and	and	CC
cord-310847-63gh2tg4	282	47	the	the	DT
cord-310847-63gh2tg4	282	48	binuclear	binuclear	NNP
cord-310847-63gh2tg4	282	49	center	center	NN
cord-310847-63gh2tg4	282	50	(	(	-LRB-
cord-310847-63gh2tg4	282	51	heme	heme	NN
cord-310847-63gh2tg4	282	52	b	b	NNP
cord-310847-63gh2tg4	282	53	3	3	CD
cord-310847-63gh2tg4	283	1	/Fe	/fe	JJ
cord-310847-63gh2tg4	284	1	B	b	NN
cord-310847-63gh2tg4	284	2	)	)	-RRB-
cord-310847-63gh2tg4	285	1	buried	bury	VBN
cord-310847-63gh2tg4	285	2	in	in	IN
cord-310847-63gh2tg4	285	3	the	the	DT
cord-310847-63gh2tg4	285	4	hydrophobic	hydrophobic	JJ
cord-310847-63gh2tg4	285	5	interior	interior	NN
cord-310847-63gh2tg4	285	6	of	of	IN
cord-310847-63gh2tg4	285	7	its	-PRON-	PRP$
cord-310847-63gh2tg4	285	8	trans	trans	JJ
cord-310847-63gh2tg4	285	9	-	-	NN
cord-310847-63gh2tg4	285	10	membrane	membrane	NN
cord-310847-63gh2tg4	285	11	region	region	NN
cord-310847-63gh2tg4	285	12	.	.	.
cord-310847-63gh2tg4	286	1	100	100	CD
cord-310847-63gh2tg4	287	1	Here	here	RB
cord-310847-63gh2tg4	287	2	,	,	,
cord-310847-63gh2tg4	287	3	Glu211	glu211	ADD
cord-310847-63gh2tg4	287	4	is	be	VBZ
cord-310847-63gh2tg4	287	5	involved	involve	VBN
cord-310847-63gh2tg4	287	6	in	in	IN
cord-310847-63gh2tg4	287	7	the	the	DT
cord-310847-63gh2tg4	287	8	coordination	coordination	NN
cord-310847-63gh2tg4	287	9	of	of	IN
cord-310847-63gh2tg4	287	10	Fe	Fe	NNP
cord-310847-63gh2tg4	287	11	B	B	NNP
cord-310847-63gh2tg4	287	12	and	and	CC
cord-310847-63gh2tg4	287	13	its	-PRON-	PRP$
cord-310847-63gh2tg4	287	14	carboxylate	carboxylate	NN
cord-310847-63gh2tg4	287	15	functions	function	NNS
cord-310847-63gh2tg4	287	16	as	as	IN
cord-310847-63gh2tg4	287	17	the	the	DT
cord-310847-63gh2tg4	287	18	shuttle	shuttle	NN
cord-310847-63gh2tg4	287	19	for	for	IN
cord-310847-63gh2tg4	287	20	catalytic	catalytic	JJ
cord-310847-63gh2tg4	287	21	protons	proton	NNS
cord-310847-63gh2tg4	287	22	from	from	IN
cord-310847-63gh2tg4	287	23	Glu280	glu280	CD
cord-310847-63gh2tg4	287	24	to	to	IN
cord-310847-63gh2tg4	287	25	the	the	DT
cord-310847-63gh2tg4	287	26	bound	bind	VBN
cord-310847-63gh2tg4	287	27	-	-	HYPH
cord-310847-63gh2tg4	287	28	NO	no	NN
cord-310847-63gh2tg4	287	29	;	;	:
cord-310847-63gh2tg4	287	30	Glu280	glu280	CD
cord-310847-63gh2tg4	287	31	,	,	,
cord-310847-63gh2tg4	287	32	which	which	WDT
cord-310847-63gh2tg4	287	33	interacts	interact	VBZ
cord-310847-63gh2tg4	287	34	with	with	IN
cord-310847-63gh2tg4	287	35	Glu211	Glu211	NNS
cord-310847-63gh2tg4	287	36	but	but	CC
cord-310847-63gh2tg4	287	37	is	be	VBZ
cord-310847-63gh2tg4	287	38	not	not	RB
cord-310847-63gh2tg4	287	39	involved	involve	VBN
cord-310847-63gh2tg4	287	40	in	in	IN
cord-310847-63gh2tg4	287	41	direct	direct	JJ
cord-310847-63gh2tg4	287	42	interaction	interaction	NN
cord-310847-63gh2tg4	287	43	with	with	IN
cord-310847-63gh2tg4	287	44	Fe	Fe	NNP
cord-310847-63gh2tg4	287	45	B	B	NNP
cord-310847-63gh2tg4	287	46	,	,	,
cord-310847-63gh2tg4	287	47	is	be	VBZ
cord-310847-63gh2tg4	287	48	an	an	DT
cord-310847-63gh2tg4	287	49	important	important	JJ
cord-310847-63gh2tg4	287	50	player	player	NN
cord-310847-63gh2tg4	287	51	of	of	IN
cord-310847-63gh2tg4	287	52	the	the	DT
cord-310847-63gh2tg4	287	53	Thr330-Ser277-Glu280-Glu211	thr330-ser277-glu280-glu211	CD
cord-310847-63gh2tg4	287	54	network	network	NN
cord-310847-63gh2tg4	287	55	that	that	WDT
cord-310847-63gh2tg4	287	56	acts	act	VBZ
cord-310847-63gh2tg4	287	57	as	as	IN
cord-310847-63gh2tg4	287	58	a	a	DT
cord-310847-63gh2tg4	287	59	delivery	delivery	NN
cord-310847-63gh2tg4	287	60	matrix	matrix	NN
cord-310847-63gh2tg4	287	61	communication	communication	NN
cord-310847-63gh2tg4	287	62	)	)	-RRB-
cord-310847-63gh2tg4	287	63	and	and	CC
cord-310847-63gh2tg4	287	64	their	-PRON-	PRP$
cord-310847-63gh2tg4	287	65	ligands	ligand	NNS
cord-310847-63gh2tg4	287	66	,	,	,
cord-310847-63gh2tg4	287	67	it	-PRON-	PRP
cord-310847-63gh2tg4	287	68	has	have	VBZ
cord-310847-63gh2tg4	287	69	been	be	VBN
cord-310847-63gh2tg4	287	70	concluded	conclude	VBN
cord-310847-63gh2tg4	287	71	that	that	IN
cord-310847-63gh2tg4	287	72	divalent	divalent	JJ
cord-310847-63gh2tg4	287	73	cations	cation	NNS
cord-310847-63gh2tg4	287	74	are	be	VBP
cord-310847-63gh2tg4	287	75	critical	critical	JJ
cord-310847-63gh2tg4	287	76	for	for	IN
cord-310847-63gh2tg4	287	77	integrin	integrin	JJ
cord-310847-63gh2tg4	287	78	interactions	interaction	NNS
cord-310847-63gh2tg4	287	79	with	with	IN
cord-310847-63gh2tg4	287	80	almost	almost	RB
cord-310847-63gh2tg4	287	81	all	all	DT
cord-310847-63gh2tg4	287	82	ligands	ligand	NNS
cord-310847-63gh2tg4	287	83	.	.	.
cord-310847-63gh2tg4	288	1	Importantly	importantly	RB
cord-310847-63gh2tg4	288	2	,	,	,
cord-310847-63gh2tg4	288	3	although	although	IN
cord-310847-63gh2tg4	288	4	divalent	divalent	JJ
cord-310847-63gh2tg4	288	5	cations	cation	NNS
cord-310847-63gh2tg4	288	6	are	be	VBP
cord-310847-63gh2tg4	288	7	bound	bind	VBN
cord-310847-63gh2tg4	288	8	to	to	IN
cord-310847-63gh2tg4	288	9	integrins	integrin	NNS
cord-310847-63gh2tg4	288	10	,	,	,
cord-310847-63gh2tg4	288	11	their	-PRON-	PRP$
cord-310847-63gh2tg4	288	12	coordination	coordination	NN
cord-310847-63gh2tg4	288	13	sphere	sphere	NN
cord-310847-63gh2tg4	288	14	is	be	VBZ
cord-310847-63gh2tg4	288	15	not	not	RB
cord-310847-63gh2tg4	288	16	completed	complete	VBN
cord-310847-63gh2tg4	288	17	and	and	CC
cord-310847-63gh2tg4	288	18	the	the	DT
cord-310847-63gh2tg4	288	19	interactions	interaction	NNS
cord-310847-63gh2tg4	288	20	between	between	IN
cord-310847-63gh2tg4	288	21	integrin	integrin	NN
cord-310847-63gh2tg4	288	22	and	and	CC
cord-310847-63gh2tg4	288	23	its	-PRON-	PRP$
cord-310847-63gh2tg4	288	24	ligands	ligand	NNS
cord-310847-63gh2tg4	288	25	typically	typically	RB
cord-310847-63gh2tg4	288	26	involve	involve	VBP
cord-310847-63gh2tg4	288	27	completing	complete	VBG
cord-310847-63gh2tg4	288	28	the	the	DT
cord-310847-63gh2tg4	288	29	metal	metal	NN
cord-310847-63gh2tg4	288	30	ion	ion	NN
cord-310847-63gh2tg4	288	31	coordination	coordination	NN
cord-310847-63gh2tg4	288	32	with	with	IN
cord-310847-63gh2tg4	288	33	an	an	DT
cord-310847-63gh2tg4	288	34	acidic	acidic	JJ
cord-310847-63gh2tg4	288	35	ligand	ligand	NN
cord-310847-63gh2tg4	288	36	residue	residue	NN
cord-310847-63gh2tg4	288	37	.	.	.
cord-310847-63gh2tg4	289	1	115	115	CD
cord-310847-63gh2tg4	290	1	For	for	IN
cord-310847-63gh2tg4	290	2	example	example	NN
cord-310847-63gh2tg4	290	3	,	,	,
cord-310847-63gh2tg4	290	4	complexes	complex	NNS
cord-310847-63gh2tg4	290	5	between	between	IN
cord-310847-63gh2tg4	290	6	the	the	DT
cord-310847-63gh2tg4	290	7	human	human	JJ
cord-310847-63gh2tg4	290	8	intercellular	intercellular	JJ
cord-310847-63gh2tg4	290	9	adhesion	adhesion	NN
cord-310847-63gh2tg4	290	10	molecule-1	molecule-1	NNP
cord-310847-63gh2tg4	290	11	(	(	-LRB-
cord-310847-63gh2tg4	290	12	ICAM-1	ICAM-1	NNP
cord-310847-63gh2tg4	290	13	)	)	-RRB-
cord-310847-63gh2tg4	290	14	and	and	CC
cord-310847-63gh2tg4	290	15	the	the	DT
cord-310847-63gh2tg4	290	16	I	I	NNP
cord-310847-63gh2tg4	290	17	domain	domain	NN
cord-310847-63gh2tg4	290	18	of	of	IN
cord-310847-63gh2tg4	290	19	its	-PRON-	PRP$
cord-310847-63gh2tg4	290	20	integrin	integrin	NN
cord-310847-63gh2tg4	290	21	receptor	receptor	NN
cord-310847-63gh2tg4	290	22	αLβ2	αLβ2	''
cord-310847-63gh2tg4	290	23	are	be	VBP
cord-310847-63gh2tg4	290	24	stabilized	stabilize	VBN
cord-310847-63gh2tg4	290	25	by	by	IN
cord-310847-63gh2tg4	290	26	a	a	DT
cord-310847-63gh2tg4	290	27	critical	critical	JJ
cord-310847-63gh2tg4	290	28	glutamate	glutamate	NN
cord-310847-63gh2tg4	290	29	residue	residue	NN
cord-310847-63gh2tg4	290	30	that	that	WDT
cord-310847-63gh2tg4	290	31	completes	complete	VBZ
cord-310847-63gh2tg4	290	32	the	the	DT
cord-310847-63gh2tg4	290	33	magnesium	magnesium	NN
cord-310847-63gh2tg4	290	34	coordination	coordination	NN
cord-310847-63gh2tg4	290	35	in	in	IN
cord-310847-63gh2tg4	290	36	integrin	integrin	NN
cord-310847-63gh2tg4	290	37	.	.	.
cord-310847-63gh2tg4	291	1	116	116	CD
cord-310847-63gh2tg4	291	2	Similarly	similarly	RB
cord-310847-63gh2tg4	291	3	,	,	,
cord-310847-63gh2tg4	291	4	in	in	IN
cord-310847-63gh2tg4	291	5	the	the	DT
cord-310847-63gh2tg4	291	6	crystal	crystal	JJ
cord-310847-63gh2tg4	291	7	structure	structure	NN
cord-310847-63gh2tg4	291	8	of	of	IN
cord-310847-63gh2tg4	291	9	a	a	DT
cord-310847-63gh2tg4	291	10	complex	complex	NN
cord-310847-63gh2tg4	291	11	between	between	IN
cord-310847-63gh2tg4	291	12	the	the	DT
cord-310847-63gh2tg4	291	13	I	I	NNP
cord-310847-63gh2tg4	291	14	domain	domain	NN
cord-310847-63gh2tg4	291	15	of	of	IN
cord-310847-63gh2tg4	291	16	a2b1	a2b1	JJ
cord-310847-63gh2tg4	291	17	integrin	integrin	NN
cord-310847-63gh2tg4	291	18	and	and	CC
cord-310847-63gh2tg4	291	19	a	a	DT
cord-310847-63gh2tg4	291	20	triple	triple	JJ
cord-310847-63gh2tg4	291	21	-	-	HYPH
cord-310847-63gh2tg4	291	22	helical	helical	JJ
cord-310847-63gh2tg4	291	23	collagen	collagen	NN
cord-310847-63gh2tg4	291	24	peptide	peptide	NN
cord-310847-63gh2tg4	291	25	containing	contain	VBG
cord-310847-63gh2tg4	291	26	a	a	DT
cord-310847-63gh2tg4	291	27	critical	critical	JJ
cord-310847-63gh2tg4	291	28	GFOGER	GFOGER	NNP
cord-310847-63gh2tg4	291	29	motif	motif	NN
cord-310847-63gh2tg4	291	30	,	,	,
cord-310847-63gh2tg4	291	31	glutamate	glutamate	NN
cord-310847-63gh2tg4	291	32	residue	residue	NN
cord-310847-63gh2tg4	291	33	from	from	IN
cord-310847-63gh2tg4	291	34	the	the	DT
cord-310847-63gh2tg4	291	35	collagen	collagen	NN
cord-310847-63gh2tg4	291	36	peptide	peptide	NN
cord-310847-63gh2tg4	291	37	completes	complete	VBZ
cord-310847-63gh2tg4	291	38	the	the	DT
cord-310847-63gh2tg4	291	39	coordination	coordination	NN
cord-310847-63gh2tg4	291	40	sphere	sphere	NN
cord-310847-63gh2tg4	291	41	of	of	IN
cord-310847-63gh2tg4	291	42	the	the	DT
cord-310847-63gh2tg4	291	43	I	I	NNP
cord-310847-63gh2tg4	291	44	domain	domain	NN
cord-310847-63gh2tg4	291	45	metal	metal	NN
cord-310847-63gh2tg4	291	46	ion	ion	NN
cord-310847-63gh2tg4	291	47	.	.	.
cord-310847-63gh2tg4	292	1	117	117	CD
cord-310847-63gh2tg4	293	1	Based	base	VBN
cord-310847-63gh2tg4	293	2	on	on	IN
cord-310847-63gh2tg4	293	3	these	these	DT
cord-310847-63gh2tg4	293	4	observations	observation	NNS
cord-310847-63gh2tg4	293	5	it	-PRON-	PRP
cord-310847-63gh2tg4	293	6	has	have	VBZ
cord-310847-63gh2tg4	293	7	been	be	VBN
cord-310847-63gh2tg4	293	8	concluded	conclude	VBN
cord-310847-63gh2tg4	293	9	that	that	IN
cord-310847-63gh2tg4	293	10	a	a	DT
cord-310847-63gh2tg4	293	11	metalglutamate	metalglutamate	JJ
cord-310847-63gh2tg4	293	12	handshake	handshake	NN
cord-310847-63gh2tg4	293	13	represents	represent	VBZ
cord-310847-63gh2tg4	293	14	a	a	DT
cord-310847-63gh2tg4	293	15	basic	basic	JJ
cord-310847-63gh2tg4	293	16	mechanism	mechanism	NN
cord-310847-63gh2tg4	293	17	of	of	IN
cord-310847-63gh2tg4	293	18	integrin	integrin	NN
cord-310847-63gh2tg4	293	19	I	-PRON-	PRP
cord-310847-63gh2tg4	293	20	domain	domain	VBP
cord-310847-63gh2tg4	293	21	interaction	interaction	NN
cord-310847-63gh2tg4	293	22	with	with	IN
cord-310847-63gh2tg4	293	23	its	-PRON-	PRP$
cord-310847-63gh2tg4	293	24	binding	bind	VBG
cord-310847-63gh2tg4	293	25	partners	partner	NNS
cord-310847-63gh2tg4	293	26	.	.	.
cord-310847-63gh2tg4	294	1	115	115	CD
cord-310847-63gh2tg4	295	1	Furthermore	furthermore	RB
cord-310847-63gh2tg4	295	2	,	,	,
cord-310847-63gh2tg4	295	3	it	-PRON-	PRP
cord-310847-63gh2tg4	295	4	is	be	VBZ
cord-310847-63gh2tg4	295	5	believed	believe	VBN
cord-310847-63gh2tg4	295	6	now	now	RB
cord-310847-63gh2tg4	295	7	that	that	IN
cord-310847-63gh2tg4	295	8	the	the	DT
cord-310847-63gh2tg4	295	9	general	general	JJ
cord-310847-63gh2tg4	295	10	mechanism	mechanism	NN
cord-310847-63gh2tg4	295	11	by	by	IN
cord-310847-63gh2tg4	295	12	which	which	WDT
cord-310847-63gh2tg4	295	13	integrins	integrin	NNS
cord-310847-63gh2tg4	295	14	,	,	,
cord-310847-63gh2tg4	295	15	these	these	DT
cord-310847-63gh2tg4	295	16	αβ	αβ	JJ
cord-310847-63gh2tg4	295	17	-	-	HYPH
cord-310847-63gh2tg4	295	18	heterodimeric	heterodimeric	JJ
cord-310847-63gh2tg4	295	19	cell	cell	NN
cord-310847-63gh2tg4	295	20	-	-	HYPH
cord-310847-63gh2tg4	295	21	surface	surface	NN
cord-310847-63gh2tg4	295	22	receptors	receptor	NNS
cord-310847-63gh2tg4	295	23	that	that	WDT
cord-310847-63gh2tg4	295	24	are	be	VBP
cord-310847-63gh2tg4	295	25	vital	vital	JJ
cord-310847-63gh2tg4	295	26	to	to	IN
cord-310847-63gh2tg4	295	27	the	the	DT
cord-310847-63gh2tg4	295	28	survival	survival	NN
cord-310847-63gh2tg4	295	29	and	and	CC
cord-310847-63gh2tg4	295	30	function	function	NN
cord-310847-63gh2tg4	295	31	of	of	IN
cord-310847-63gh2tg4	295	32	nucleated	nucleated	JJ
cord-310847-63gh2tg4	295	33	cells	cell	NNS
cord-310847-63gh2tg4	295	34	,	,	,
cord-310847-63gh2tg4	295	35	recognize	recognize	VBP
cord-310847-63gh2tg4	295	36	their	-PRON-	PRP$
cord-310847-63gh2tg4	295	37	structurally	structurally	RB
cord-310847-63gh2tg4	295	38	diverse	diverse	JJ
cord-310847-63gh2tg4	295	39	ligands	ligand	NNS
cord-310847-63gh2tg4	295	40	relies	rely	VBZ
cord-310847-63gh2tg4	295	41	on	on	IN
cord-310847-63gh2tg4	295	42	specific	specific	JJ
cord-310847-63gh2tg4	295	43	glutamic	glutamic	NN
cord-310847-63gh2tg4	295	44	-	-	HYPH
cord-310847-63gh2tg4	295	45	acid	acid	NN
cord-310847-63gh2tg4	295	46	-	-	HYPH
cord-310847-63gh2tg4	295	47	or	or	CC
cord-310847-63gh2tg4	295	48	aspartic	aspartic	JJ
cord-310847-63gh2tg4	295	49	-	-	HYPH
cord-310847-63gh2tg4	295	50	acid	acid	NN
cord-310847-63gh2tg4	295	51	-	-	HYPH
cord-310847-63gh2tg4	295	52	based	base	VBN
cord-310847-63gh2tg4	295	53	sequence	sequence	NN
cord-310847-63gh2tg4	295	54	motifs	motif	NNS
cord-310847-63gh2tg4	295	55	that	that	WDT
cord-310847-63gh2tg4	295	56	function	function	VBP
cord-310847-63gh2tg4	295	57	in	in	IN
cord-310847-63gh2tg4	295	58	a	a	DT
cord-310847-63gh2tg4	295	59	divalent	divalent	JJ
cord-310847-63gh2tg4	295	60	cation	cation	NN
cord-310847-63gh2tg4	295	61	-	-	HYPH
cord-310847-63gh2tg4	295	62	dependent	dependent	JJ
cord-310847-63gh2tg4	295	63	and	and	CC
cord-310847-63gh2tg4	295	64	conformationally	conformationally	RB
cord-310847-63gh2tg4	295	65	sensitive	sensitive	JJ
cord-310847-63gh2tg4	295	66	manner	manner	NN
cord-310847-63gh2tg4	295	67	.	.	.
cord-310847-63gh2tg4	296	1	118	118	CD
cord-310847-63gh2tg4	297	1	The	the	DT
cord-310847-63gh2tg4	297	2	levels	level	NNS
cord-310847-63gh2tg4	297	3	of	of	IN
cord-310847-63gh2tg4	297	4	intracellular	intracellular	JJ
cord-310847-63gh2tg4	297	5	zinc	zinc	NN
cord-310847-63gh2tg4	297	6	in	in	IN
cord-310847-63gh2tg4	297	7	living	living	NN
cord-310847-63gh2tg4	297	8	cells	cell	NNS
cord-310847-63gh2tg4	297	9	are	be	VBP
cord-310847-63gh2tg4	297	10	crucial	crucial	JJ
cord-310847-63gh2tg4	297	11	for	for	IN
cord-310847-63gh2tg4	297	12	managing	manage	VBG
cord-310847-63gh2tg4	297	13	various	various	JJ
cord-310847-63gh2tg4	297	14	cellular	cellular	JJ
cord-310847-63gh2tg4	297	15	processes	process	NNS
cord-310847-63gh2tg4	297	16	,	,	,
cord-310847-63gh2tg4	297	17	such	such	JJ
cord-310847-63gh2tg4	297	18	as	as	IN
cord-310847-63gh2tg4	297	19	growth	growth	NN
cord-310847-63gh2tg4	297	20	,	,	,
cord-310847-63gh2tg4	297	21	development	development	NN
cord-310847-63gh2tg4	297	22	and	and	CC
cord-310847-63gh2tg4	297	23	differentiation	differentiation	NN
cord-310847-63gh2tg4	297	24	.	.	.
cord-310847-63gh2tg4	298	1	Zinc	zinc	NN
cord-310847-63gh2tg4	298	2	is	be	VBZ
cord-310847-63gh2tg4	298	3	involved	involve	VBN
cord-310847-63gh2tg4	298	4	in	in	IN
cord-310847-63gh2tg4	298	5	protein	protein	NN
cord-310847-63gh2tg4	298	6	,	,	,
cord-310847-63gh2tg4	298	7	nucleic	nucleic	JJ
cord-310847-63gh2tg4	298	8	acid	acid	NN
cord-310847-63gh2tg4	298	9	,	,	,
cord-310847-63gh2tg4	298	10	carbohydrate	carbohydrate	NN
cord-310847-63gh2tg4	298	11	and	and	CC
cord-310847-63gh2tg4	298	12	lipid	lipid	NN
cord-310847-63gh2tg4	298	13	metabolism	metabolism	NN
cord-310847-63gh2tg4	298	14	and	and	CC
cord-310847-63gh2tg4	298	15	also	also	RB
cord-310847-63gh2tg4	298	16	plays	play	VBZ
cord-310847-63gh2tg4	298	17	a	a	DT
cord-310847-63gh2tg4	298	18	role	role	NN
cord-310847-63gh2tg4	298	19	in	in	IN
cord-310847-63gh2tg4	298	20	the	the	DT
cord-310847-63gh2tg4	298	21	control	control	NN
cord-310847-63gh2tg4	298	22	of	of	IN
cord-310847-63gh2tg4	298	23	gene	gene	NN
cord-310847-63gh2tg4	298	24	transcription	transcription	NN
cord-310847-63gh2tg4	298	25	and	and	CC
cord-310847-63gh2tg4	298	26	the	the	DT
cord-310847-63gh2tg4	298	27	coordination	coordination	NN
cord-310847-63gh2tg4	298	28	of	of	IN
cord-310847-63gh2tg4	298	29	other	other	JJ
cord-310847-63gh2tg4	298	30	biological	biological	JJ
cord-310847-63gh2tg4	298	31	processes	process	NNS
cord-310847-63gh2tg4	298	32	controlled	control	VBN
cord-310847-63gh2tg4	298	33	by	by	IN
cord-310847-63gh2tg4	298	34	proteins	protein	NNS
cord-310847-63gh2tg4	298	35	containing	contain	VBG
cord-310847-63gh2tg4	298	36	DNA	dna	NN
cord-310847-63gh2tg4	298	37	-	-	HYPH
cord-310847-63gh2tg4	298	38	binding	bind	VBG
cord-310847-63gh2tg4	298	39	zinc	zinc	NN
cord-310847-63gh2tg4	298	40	finger	finger	NN
cord-310847-63gh2tg4	298	41	motifs	motif	NNS
cord-310847-63gh2tg4	298	42	,	,	,
cord-310847-63gh2tg4	298	43	RING	ring	VB
cord-310847-63gh2tg4	298	44	fingers	finger	NNS
cord-310847-63gh2tg4	298	45	and	and	CC
cord-310847-63gh2tg4	298	46	LIM	LIM	NNP
cord-310847-63gh2tg4	298	47	domains	domain	NNS
cord-310847-63gh2tg4	298	48	.	.	.
cord-310847-63gh2tg4	299	1	119	119	CD
cord-310847-63gh2tg4	300	1	The	the	DT
cord-310847-63gh2tg4	300	2	physiologically	physiologically	RB
cord-310847-63gh2tg4	300	3	relevant	relevant	JJ
cord-310847-63gh2tg4	300	4	intracellular	intracellular	JJ
cord-310847-63gh2tg4	300	5	levels	level	NNS
cord-310847-63gh2tg4	300	6	of	of	IN
cord-310847-63gh2tg4	300	7	zinc	zinc	NN
cord-310847-63gh2tg4	300	8	are	be	VBP
cord-310847-63gh2tg4	300	9	controlled	control	VBN
cord-310847-63gh2tg4	300	10	by	by	IN
cord-310847-63gh2tg4	300	11	specific	specific	JJ
cord-310847-63gh2tg4	300	12	zinc	zinc	NN
cord-310847-63gh2tg4	300	13	transporters	transporter	NNS
cord-310847-63gh2tg4	300	14	which	which	WDT
cord-310847-63gh2tg4	300	15	mostly	mostly	RB
cord-310847-63gh2tg4	300	16	transport	transport	VBP
cord-310847-63gh2tg4	300	17	zinc	zinc	NN
cord-310847-63gh2tg4	300	18	into	into	IN
cord-310847-63gh2tg4	300	19	cells	cell	NNS
cord-310847-63gh2tg4	300	20	from	from	IN
cord-310847-63gh2tg4	300	21	outside	outside	RB
cord-310847-63gh2tg4	300	22	.	.	.
cord-310847-63gh2tg4	301	1	105	105	CD
cord-310847-63gh2tg4	301	2	Members	member	NNS
cord-310847-63gh2tg4	301	3	of	of	IN
cord-310847-63gh2tg4	301	4	one	one	CD
cord-310847-63gh2tg4	301	5	of	of	IN
cord-310847-63gh2tg4	301	6	the	the	DT
cord-310847-63gh2tg4	301	7	subfamilies	subfamily	NNS
cord-310847-63gh2tg4	301	8	of	of	IN
cord-310847-63gh2tg4	301	9	these	these	DT
cord-310847-63gh2tg4	301	10	transporters	transporter	NNS
cord-310847-63gh2tg4	301	11	,	,	,
cord-310847-63gh2tg4	301	12	LIV-1	LIV-1	NNP
cord-310847-63gh2tg4	301	13	subfamily	subfamily	NN
cord-310847-63gh2tg4	301	14	of	of	IN
cord-310847-63gh2tg4	301	15	ZIP	zip	NN
cord-310847-63gh2tg4	301	16	zinc	zinc	NN
cord-310847-63gh2tg4	301	17	Transporters	transporter	NNS
cord-310847-63gh2tg4	301	18	(	(	-LRB-
cord-310847-63gh2tg4	301	19	LZT	LZT	NNP
cord-310847-63gh2tg4	301	20	)	)	-RRB-
cord-310847-63gh2tg4	301	21	,	,	,
cord-310847-63gh2tg4	301	22	being	be	VBG
cord-310847-63gh2tg4	301	23	similar	similar	JJ
cord-310847-63gh2tg4	301	24	to	to	IN
cord-310847-63gh2tg4	301	25	other	other	JJ
cord-310847-63gh2tg4	301	26	ZIP	zip	NN
cord-310847-63gh2tg4	301	27	transporters	transporter	NNS
cord-310847-63gh2tg4	301	28	in	in	IN
cord-310847-63gh2tg4	301	29	secondary	secondary	JJ
cord-310847-63gh2tg4	301	30	structure	structure	NN
cord-310847-63gh2tg4	301	31	and	and	CC
cord-310847-63gh2tg4	301	32	ability	ability	NN
cord-310847-63gh2tg4	301	33	to	to	TO
cord-310847-63gh2tg4	301	34	transport	transport	VB
cord-310847-63gh2tg4	301	35	metal	metal	NN
cord-310847-63gh2tg4	301	36	ions	ion	NNS
cord-310847-63gh2tg4	301	37	across	across	IN
cord-310847-63gh2tg4	301	38	the	the	DT
cord-310847-63gh2tg4	301	39	plasma	plasma	NN
cord-310847-63gh2tg4	301	40	membrane	membrane	NN
cord-310847-63gh2tg4	301	41	or	or	CC
cord-310847-63gh2tg4	301	42	intracellular	intracellular	JJ
cord-310847-63gh2tg4	301	43	membranes	membrane	NNS
cord-310847-63gh2tg4	301	44	,	,	,
cord-310847-63gh2tg4	301	45	possess	possess	VBP
cord-310847-63gh2tg4	301	46	a	a	DT
cord-310847-63gh2tg4	301	47	unique	unique	JJ
cord-310847-63gh2tg4	301	48	HEXPHEXGD	hexphexgd	NN
cord-310847-63gh2tg4	301	49	motif	motif	NN
cord-310847-63gh2tg4	301	50	containing	contain	VBG
cord-310847-63gh2tg4	301	51	conserved	conserve	VBN
cord-310847-63gh2tg4	301	52	proline	proline	NN
cord-310847-63gh2tg4	301	53	and	and	CC
cord-310847-63gh2tg4	301	54	glutamic	glutamic	NN
cord-310847-63gh2tg4	301	55	acid	acid	NN
cord-310847-63gh2tg4	301	56	residues	residue	NNS
cord-310847-63gh2tg4	301	57	,	,	,
cord-310847-63gh2tg4	301	58	that	that	WDT
cord-310847-63gh2tg4	301	59	fits	fit	VBZ
cord-310847-63gh2tg4	301	60	the	the	DT
cord-310847-63gh2tg4	301	61	consensus	consensus	NN
cord-310847-63gh2tg4	301	62	sequence	sequence	NN
cord-310847-63gh2tg4	301	63	for	for	IN
cord-310847-63gh2tg4	301	64	the	the	DT
cord-310847-63gh2tg4	301	65	catalytic	catalytic	JJ
cord-310847-63gh2tg4	301	66	zinc	zinc	NN
cord-310847-63gh2tg4	301	67	-	-	HYPH
cord-310847-63gh2tg4	301	68	biding	bide	VBG
cord-310847-63gh2tg4	301	69	site	site	NN
cord-310847-63gh2tg4	301	70	of	of	IN
cord-310847-63gh2tg4	301	71	matrix	matrix	NN
cord-310847-63gh2tg4	301	72	metalloproteinases	metalloproteinase	NNS
cord-310847-63gh2tg4	301	73	(	(	-LRB-
cord-310847-63gh2tg4	301	74	HEXXHXXGXXH	HEXXHXXGXXH	NNP
cord-310847-63gh2tg4	301	75	)	)	-RRB-
cord-310847-63gh2tg4	301	76	,	,	,
cord-310847-63gh2tg4	301	77	and	and	CC
cord-310847-63gh2tg4	301	78	which	which	WDT
cord-310847-63gh2tg4	301	79	is	be	VBZ
cord-310847-63gh2tg4	301	80	unprecedented	unprecedented	JJ
cord-310847-63gh2tg4	301	81	in	in	IN
cord-310847-63gh2tg4	301	82	other	other	JJ
cord-310847-63gh2tg4	301	83	zinc	zinc	NN
cord-310847-63gh2tg4	301	84	transporters	transporter	NNS
cord-310847-63gh2tg4	301	85	.	.	.
cord-310847-63gh2tg4	302	1	105	105	CD
cord-310847-63gh2tg4	303	1	In	in	IN
cord-310847-63gh2tg4	303	2	addition	addition	NN
cord-310847-63gh2tg4	303	3	to	to	IN
cord-310847-63gh2tg4	303	4	this	this	DT
cord-310847-63gh2tg4	303	5	set	set	NN
cord-310847-63gh2tg4	303	6	of	of	IN
cord-310847-63gh2tg4	303	7	specific	specific	JJ
cord-310847-63gh2tg4	303	8	examples	example	NNS
cord-310847-63gh2tg4	303	9	,	,	,
cord-310847-63gh2tg4	303	10	one	one	PRP
cord-310847-63gh2tg4	303	11	should	should	MD
cord-310847-63gh2tg4	303	12	keep	keep	VB
cord-310847-63gh2tg4	303	13	in	in	IN
cord-310847-63gh2tg4	303	14	mind	mind	NN
cord-310847-63gh2tg4	303	15	that	that	IN
cord-310847-63gh2tg4	303	16	all	all	DT
cord-310847-63gh2tg4	303	17	structures	structure	NNS
cord-310847-63gh2tg4	303	18	of	of	IN
cord-310847-63gh2tg4	303	19	the	the	DT
cord-310847-63gh2tg4	303	20	Ca	Ca	NNP
cord-310847-63gh2tg4	303	21	2	2	CD
cord-310847-63gh2tg4	303	22	+	+	SYM
cord-310847-63gh2tg4	303	23	-binding	-binding	NN
cord-310847-63gh2tg4	303	24	domains	domain	NNS
cord-310847-63gh2tg4	303	25	have	have	VBP
cord-310847-63gh2tg4	303	26	in	in	IN
cord-310847-63gh2tg4	303	27	common	common	JJ
cord-310847-63gh2tg4	303	28	a	a	DT
cord-310847-63gh2tg4	303	29	high	high	JJ
cord-310847-63gh2tg4	303	30	negative	negative	JJ
cord-310847-63gh2tg4	303	31	surface	surface	NN
cord-310847-63gh2tg4	303	32	potential	potential	NN
cord-310847-63gh2tg4	303	33	usually	usually	RB
cord-310847-63gh2tg4	303	34	associated	associate	VBN
cord-310847-63gh2tg4	303	35	with	with	IN
cord-310847-63gh2tg4	303	36	Asp	Asp	NNP
cord-310847-63gh2tg4	303	37	or	or	CC
cord-310847-63gh2tg4	303	38	Glu	Glu	NNP
cord-310847-63gh2tg4	303	39	residues	residue	NNS
cord-310847-63gh2tg4	303	40	.	.	.
cord-310847-63gh2tg4	304	1	120	120	CD
cord-310847-63gh2tg4	305	1	Therefore	therefore	RB
cord-310847-63gh2tg4	305	2	,	,	,
cord-310847-63gh2tg4	305	3	important	important	JJ
cord-310847-63gh2tg4	305	4	glutamic	glutamic	NN
cord-310847-63gh2tg4	305	5	acid	acid	NN
cord-310847-63gh2tg4	305	6	residues	residue	NNS
cord-310847-63gh2tg4	305	7	responsible	responsible	JJ
cord-310847-63gh2tg4	305	8	for	for	IN
cord-310847-63gh2tg4	305	9	calcium	calcium	NN
cord-310847-63gh2tg4	305	10	coordination	coordination	NN
cord-310847-63gh2tg4	305	11	can	can	MD
cord-310847-63gh2tg4	305	12	be	be	VB
cord-310847-63gh2tg4	305	13	found	find	VBN
cord-310847-63gh2tg4	305	14	in	in	IN
cord-310847-63gh2tg4	305	15	various	various	JJ
cord-310847-63gh2tg4	305	16	members	member	NNS
cord-310847-63gh2tg4	305	17	of	of	IN
cord-310847-63gh2tg4	305	18	the	the	DT
cord-310847-63gh2tg4	305	19	major	major	JJ
cord-310847-63gh2tg4	306	1	Ca	ca	NN
cord-310847-63gh2tg4	306	2	2	2	CD
cord-310847-63gh2tg4	306	3	+	+	SYM
cord-310847-63gh2tg4	306	4	-binding	-binding	NN
cord-310847-63gh2tg4	306	5	proteins	protein	NNS
cord-310847-63gh2tg4	306	6	,	,	,
cord-310847-63gh2tg4	306	7	such	such	JJ
cord-310847-63gh2tg4	306	8	as	as	IN
cord-310847-63gh2tg4	306	9	EF	ef	NN
cord-310847-63gh2tg4	306	10	-	-	HYPH
cord-310847-63gh2tg4	306	11	hand	hand	NN
cord-310847-63gh2tg4	306	12	domains	domain	NNS
cord-310847-63gh2tg4	306	13	,	,	,
cord-310847-63gh2tg4	306	14	EGF	EGF	NNP
cord-310847-63gh2tg4	306	15	-	-	HYPH
cord-310847-63gh2tg4	306	16	like	like	JJ
cord-310847-63gh2tg4	306	17	domains	domain	NNS
cord-310847-63gh2tg4	306	18	,	,	,
cord-310847-63gh2tg4	306	19	γ	γ	NN
cord-310847-63gh2tg4	306	20	-	-	HYPH
cord-310847-63gh2tg4	306	21	carboxyl	carboxyl	NN
cord-310847-63gh2tg4	306	22	glutamic	glutamic	NN
cord-310847-63gh2tg4	306	23	acid	acid	NN
cord-310847-63gh2tg4	306	24	(	(	-LRB-
cord-310847-63gh2tg4	306	25	GLA)-rich	gla)-rich	ADD
cord-310847-63gh2tg4	306	26	domains	domain	NNS
cord-310847-63gh2tg4	306	27	,	,	,
cord-310847-63gh2tg4	306	28	cadherin	cadherin	NN
cord-310847-63gh2tg4	306	29	domains	domain	NNS
cord-310847-63gh2tg4	306	30	,	,	,
cord-310847-63gh2tg4	307	1	Ca	ca	RB
cord-310847-63gh2tg4	307	2	2	2	CD
cord-310847-63gh2tg4	308	1	+	+	CC
cord-310847-63gh2tg4	309	1	-dependent	-dependent	JJ
cord-310847-63gh2tg4	309	2	(	(	-LRB-
cord-310847-63gh2tg4	309	3	C)-type	C)-type	NNP
cord-310847-63gh2tg4	309	4	lectin	lectin	NN
cord-310847-63gh2tg4	309	5	-	-	HYPH
cord-310847-63gh2tg4	309	6	like	like	JJ
cord-310847-63gh2tg4	309	7	domains	domain	NNS
cord-310847-63gh2tg4	309	8	and	and	CC
cord-310847-63gh2tg4	309	9	Ca	Ca	NNP
cord-310847-63gh2tg4	309	10	2	2	CD
cord-310847-63gh2tg4	309	11	+	+	SYM
cord-310847-63gh2tg4	309	12	-binding	-binde	VBG
cord-310847-63gh2tg4	309	13	pockets	pocket	NNS
cord-310847-63gh2tg4	309	14	of	of	IN
cord-310847-63gh2tg4	309	15	family	family	NN
cord-310847-63gh2tg4	309	16	C	c	NN
cord-310847-63gh2tg4	309	17	G	g	NN
cord-310847-63gh2tg4	309	18	-	-	HYPH
cord-310847-63gh2tg4	309	19	protein	protein	NN
cord-310847-63gh2tg4	309	20	-	-	HYPH
cord-310847-63gh2tg4	309	21	coupled	couple	VBN
cord-310847-63gh2tg4	309	22	receptors	receptor	NNS
cord-310847-63gh2tg4	309	23	.	.	.
cord-310847-63gh2tg4	310	1	120	120	CD
cord-310847-63gh2tg4	311	1	A	a	DT
cord-310847-63gh2tg4	311	2	particularly	particularly	RB
cord-310847-63gh2tg4	311	3	intriguing	intriguing	JJ
cord-310847-63gh2tg4	311	4	role	role	NN
cord-310847-63gh2tg4	311	5	was	be	VBD
cord-310847-63gh2tg4	311	6	described	describe	VBN
cord-310847-63gh2tg4	311	7	for	for	IN
cord-310847-63gh2tg4	311	8	the	the	DT
cord-310847-63gh2tg4	311	9	N	n	CD
cord-310847-63gh2tg4	311	10	-	-	HYPH
cord-310847-63gh2tg4	311	11	terminal	terminal	JJ
cord-310847-63gh2tg4	311	12	glutamic	glutamic	NN
cord-310847-63gh2tg4	311	13	acid	acid	NN
cord-310847-63gh2tg4	311	14	residues	residue	NNS
cord-310847-63gh2tg4	311	15	in	in	IN
cord-310847-63gh2tg4	311	16	the	the	DT
cord-310847-63gh2tg4	311	17	canonical	canonical	JJ
cord-310847-63gh2tg4	311	18	Ca	Ca	NNP
cord-310847-63gh2tg4	311	19	2	2	CD
cord-310847-63gh2tg4	311	20	+	+	CC
cord-310847-63gh2tg4	311	21	-protein	-protein	UH
cord-310847-63gh2tg4	311	22	,	,	,
cord-310847-63gh2tg4	311	23	α	α	NN
cord-310847-63gh2tg4	311	24	-	-	HYPH
cord-310847-63gh2tg4	311	25	lactabumin	lactabumin	NNP
cord-310847-63gh2tg4	311	26	,	,	,
cord-310847-63gh2tg4	311	27	121	121	CD
cord-310847-63gh2tg4	311	28	which	which	WDT
cord-310847-63gh2tg4	311	29	is	be	VBZ
cord-310847-63gh2tg4	311	30	frequently	frequently	RB
cord-310847-63gh2tg4	311	31	used	use	VBN
cord-310847-63gh2tg4	311	32	as	as	IN
cord-310847-63gh2tg4	311	33	a	a	DT
cord-310847-63gh2tg4	311	34	model	model	NN
cord-310847-63gh2tg4	311	35	protein	protein	NN
cord-310847-63gh2tg4	311	36	in	in	IN
cord-310847-63gh2tg4	311	37	folding	fold	VBG
cord-310847-63gh2tg4	311	38	studies	study	NNS
cord-310847-63gh2tg4	311	39	and	and	CC
cord-310847-63gh2tg4	311	40	in	in	IN
cord-310847-63gh2tg4	311	41	studies	study	NNS
cord-310847-63gh2tg4	311	42	on	on	IN
cord-310847-63gh2tg4	311	43	the	the	DT
cord-310847-63gh2tg4	311	44	effect	effect	NN
cord-310847-63gh2tg4	311	45	of	of	IN
cord-310847-63gh2tg4	311	46	calcium	calcium	NN
cord-310847-63gh2tg4	311	47	binding	bind	VBG
cord-310847-63gh2tg4	311	48	on	on	IN
cord-310847-63gh2tg4	311	49	protein	protein	NN
cord-310847-63gh2tg4	311	50	structure	structure	NN
cord-310847-63gh2tg4	311	51	,	,	,
cord-310847-63gh2tg4	311	52	stability	stability	NN
cord-310847-63gh2tg4	311	53	and	and	CC
cord-310847-63gh2tg4	311	54	folding	folding	NN
cord-310847-63gh2tg4	311	55	.	.	.
cord-310847-63gh2tg4	312	1	For	for	IN
cord-310847-63gh2tg4	312	2	example	example	NN
cord-310847-63gh2tg4	312	3	,	,	,
cord-310847-63gh2tg4	312	4	In	in	IN
cord-310847-63gh2tg4	312	5	nudix	nudix	NN
cord-310847-63gh2tg4	312	6	hydrolases	hydrolase	NNS
cord-310847-63gh2tg4	312	7	(	(	-LRB-
cord-310847-63gh2tg4	312	8	which	which	WDT
cord-310847-63gh2tg4	312	9	is	be	VBZ
cord-310847-63gh2tg4	312	10	a	a	DT
cord-310847-63gh2tg4	312	11	family	family	NN
cord-310847-63gh2tg4	312	12	of	of	IN
cord-310847-63gh2tg4	312	13	Mg	Mg	NNP
cord-310847-63gh2tg4	312	14	2	2	CD
cord-310847-63gh2tg4	312	15	+	+	SYM
cord-310847-63gh2tg4	312	16	-requiring	-require	VBG
cord-310847-63gh2tg4	312	17	enzymes	enzyme	NNS
cord-310847-63gh2tg4	312	18	that	that	WDT
cord-310847-63gh2tg4	312	19	catalyze	catalyze	VBP
cord-310847-63gh2tg4	312	20	the	the	DT
cord-310847-63gh2tg4	312	21	hydrolysis	hydrolysis	NN
cord-310847-63gh2tg4	312	22	of	of	IN
cord-310847-63gh2tg4	312	23	nucleoside	nucleoside	NN
cord-310847-63gh2tg4	312	24	diphosphates	diphosphate	NNS
cord-310847-63gh2tg4	312	25	linked	link	VBN
cord-310847-63gh2tg4	312	26	to	to	IN
cord-310847-63gh2tg4	312	27	other	other	JJ
cord-310847-63gh2tg4	312	28	moieties	moiety	NNS
cord-310847-63gh2tg4	312	29	)	)	-RRB-
cord-310847-63gh2tg4	312	30	there	there	EX
cord-310847-63gh2tg4	312	31	is	be	VBZ
cord-310847-63gh2tg4	312	32	a	a	DT
cord-310847-63gh2tg4	312	33	specific	specific	JJ
cord-310847-63gh2tg4	312	34	motif	motif	NN
cord-310847-63gh2tg4	312	35	,	,	,
cord-310847-63gh2tg4	312	36	Nudix	Nudix	NNP
cord-310847-63gh2tg4	312	37	box	box	NN
cord-310847-63gh2tg4	312	38	(	(	-LRB-
cord-310847-63gh2tg4	312	39	GX	GX	NNP
cord-310847-63gh2tg4	312	40	5	5	CD
cord-310847-63gh2tg4	312	41	EX	EX	NNP
cord-310847-63gh2tg4	312	42	7	7	CD
cord-310847-63gh2tg4	312	43	REUXEEXGU	REUXEEXGU	NNP
cord-310847-63gh2tg4	312	44	,	,	,
cord-310847-63gh2tg4	312	45	where	where	WRB
cord-310847-63gh2tg4	312	46	U	U	NNP
cord-310847-63gh2tg4	312	47	is	be	VBZ
cord-310847-63gh2tg4	312	48	a	a	DT
cord-310847-63gh2tg4	312	49	bulky	bulky	JJ
cord-310847-63gh2tg4	312	50	hydrophobic	hydrophobic	JJ
cord-310847-63gh2tg4	312	51	residue	residue	NN
cord-310847-63gh2tg4	312	52	)	)	-RRB-
cord-310847-63gh2tg4	312	53	,	,	,
cord-310847-63gh2tg4	312	54	that	that	WDT
cord-310847-63gh2tg4	312	55	forms	form	VBZ
cord-310847-63gh2tg4	312	56	a	a	DT
cord-310847-63gh2tg4	312	57	loop	loop	NN
cord-310847-63gh2tg4	312	58	-	-	HYPH
cord-310847-63gh2tg4	312	59	α	α	VBG
cord-310847-63gh2tg4	312	60	helix	helix	NN
cord-310847-63gh2tg4	312	61	-	-	HYPH
cord-310847-63gh2tg4	312	62	loop	loop	NN
cord-310847-63gh2tg4	312	63	structural	structural	JJ
cord-310847-63gh2tg4	312	64	motif	motif	NN
cord-310847-63gh2tg4	312	65	that	that	WDT
cord-310847-63gh2tg4	312	66	functions	function	VBZ
cord-310847-63gh2tg4	312	67	as	as	IN
cord-310847-63gh2tg4	312	68	a	a	DT
cord-310847-63gh2tg4	312	69	common	common	JJ
cord-310847-63gh2tg4	312	70	Mg	Mg	NNP
cord-310847-63gh2tg4	312	71	2	2	CD
cord-310847-63gh2tg4	312	72	+	+	SYM
cord-310847-63gh2tg4	312	73	-binding	-binding	NN
cord-310847-63gh2tg4	312	74	and	and	CC
cord-310847-63gh2tg4	312	75	catalytic	catalytic	JJ
cord-310847-63gh2tg4	312	76	site	site	NN
cord-310847-63gh2tg4	312	77	.	.	.
cord-310847-63gh2tg4	313	1	111	111	CD
cord-310847-63gh2tg4	314	1	It	-PRON-	PRP
cord-310847-63gh2tg4	314	2	was	be	VBD
cord-310847-63gh2tg4	314	3	emphasized	emphasize	VBN
cord-310847-63gh2tg4	314	4	that	that	IN
cord-310847-63gh2tg4	314	5	the	the	DT
cord-310847-63gh2tg4	314	6	overall	overall	JJ
cord-310847-63gh2tg4	314	7	catalytic	catalytic	JJ
cord-310847-63gh2tg4	314	8	powers	power	NNS
cord-310847-63gh2tg4	314	9	of	of	IN
cord-310847-63gh2tg4	314	10	Nudix	Nudix	NNP
cord-310847-63gh2tg4	314	11	hydrolases	hydrolase	NNS
cord-310847-63gh2tg4	314	12	consists	consist	VBZ
cord-310847-63gh2tg4	314	13	in	in	IN
cord-310847-63gh2tg4	314	14	accelerating	accelerate	VBG
cord-310847-63gh2tg4	314	15	the	the	DT
cord-310847-63gh2tg4	314	16	reaction	reaction	NN
cord-310847-63gh2tg4	314	17	rate	rate	NN
cord-310847-63gh2tg4	314	18	by	by	IN
cord-310847-63gh2tg4	314	19	10	10	CD
cord-310847-63gh2tg4	314	20	9	9	CD
cord-310847-63gh2tg4	314	21	to	to	TO
cord-310847-63gh2tg4	314	22	10	10	CD
cord-310847-63gh2tg4	314	23	12	12	CD
cord-310847-63gh2tg4	314	24	times	time	NNS
cord-310847-63gh2tg4	314	25	.	.	.
cord-310847-63gh2tg4	315	1	The	the	DT
cord-310847-63gh2tg4	315	2	reactions	reaction	NNS
cord-310847-63gh2tg4	315	3	are	be	VBP
cord-310847-63gh2tg4	315	4	accelerated	accelerate	VBN
cord-310847-63gh2tg4	315	5	10	10	CD
cord-310847-63gh2tg4	315	6	3	3	CD
cord-310847-63gh2tg4	315	7	-10	-10	CD
cord-310847-63gh2tg4	315	8	5	5	CD
cord-310847-63gh2tg4	315	9	-times	-times	CD
cord-310847-63gh2tg4	315	10	by	by	IN
cord-310847-63gh2tg4	315	11	general	general	JJ
cord-310847-63gh2tg4	315	12	base	base	NN
cord-310847-63gh2tg4	315	13	catalysis	catalysis	NN
cord-310847-63gh2tg4	315	14	by	by	IN
cord-310847-63gh2tg4	315	15	a	a	DT
cord-310847-63gh2tg4	315	16	glutamate	glutamate	NN
cord-310847-63gh2tg4	315	17	residue	residue	NN
cord-310847-63gh2tg4	315	18	within	within	IN
cord-310847-63gh2tg4	315	19	,	,	,
cord-310847-63gh2tg4	315	20	or	or	CC
cord-310847-63gh2tg4	315	21	beyond	beyond	IN
cord-310847-63gh2tg4	315	22	the	the	DT
cord-310847-63gh2tg4	315	23	Nudix	Nudix	NNP
cord-310847-63gh2tg4	315	24	box	box	NN
cord-310847-63gh2tg4	315	25	,	,	,
cord-310847-63gh2tg4	315	26	or	or	CC
cord-310847-63gh2tg4	315	27	by	by	IN
cord-310847-63gh2tg4	315	28	a	a	DT
cord-310847-63gh2tg4	315	29	histidine	histidine	NN
cord-310847-63gh2tg4	315	30	beyond	beyond	IN
cord-310847-63gh2tg4	315	31	the	the	DT
cord-310847-63gh2tg4	315	32	Nudix	Nudix	NNP
cord-310847-63gh2tg4	315	33	box	box	NN
cord-310847-63gh2tg4	315	34	.	.	.
cord-310847-63gh2tg4	316	1	The	the	DT
cord-310847-63gh2tg4	316	2	additional	additional	JJ
cord-310847-63gh2tg4	316	3	10	10	CD
cord-310847-63gh2tg4	316	4	3	3	CD
cord-310847-63gh2tg4	316	5	-10	-10	SYM
cord-310847-63gh2tg4	316	6	5	5	CD
cord-310847-63gh2tg4	316	7	-fold	-fold	NN
cord-310847-63gh2tg4	316	8	rate	rate	NN
cord-310847-63gh2tg4	316	9	acceleration	acceleration	NN
cord-310847-63gh2tg4	316	10	is	be	VBZ
cord-310847-63gh2tg4	316	11	due	due	JJ
cord-310847-63gh2tg4	316	12	to	to	IN
cord-310847-63gh2tg4	316	13	the	the	DT
cord-310847-63gh2tg4	316	14	Lewis	Lewis	NNP
cord-310847-63gh2tg4	316	15	acid	acid	NN
cord-310847-63gh2tg4	316	16	catalysis	catalysis	NN
cord-310847-63gh2tg4	316	17	provided	provide	VBN
cord-310847-63gh2tg4	316	18	by	by	IN
cord-310847-63gh2tg4	316	19	one	one	CD
cord-310847-63gh2tg4	316	20	,	,	,
cord-310847-63gh2tg4	316	21	two	two	CD
cord-310847-63gh2tg4	316	22	,	,	,
cord-310847-63gh2tg4	316	23	or	or	CC
cord-310847-63gh2tg4	316	24	three	three	CD
cord-310847-63gh2tg4	316	25	divalent	divalent	JJ
cord-310847-63gh2tg4	316	26	cations	cation	NNS
cord-310847-63gh2tg4	316	27	.	.	.
cord-310847-63gh2tg4	317	1	One	one	CD
cord-310847-63gh2tg4	317	2	divalent	divalent	JJ
cord-310847-63gh2tg4	317	3	cation	cation	NN
cord-310847-63gh2tg4	317	4	is	be	VBZ
cord-310847-63gh2tg4	317	5	coordinated	coordinate	VBN
cord-310847-63gh2tg4	317	6	by	by	IN
cord-310847-63gh2tg4	317	7	two	two	CD
cord-310847-63gh2tg4	317	8	or	or	CC
cord-310847-63gh2tg4	317	9	three	three	CD
cord-310847-63gh2tg4	317	10	conserved	conserved	JJ
cord-310847-63gh2tg4	317	11	residues	residue	NNS
cord-310847-63gh2tg4	317	12	of	of	IN
cord-310847-63gh2tg4	317	13	the	the	DT
cord-310847-63gh2tg4	317	14	Nudix	Nudix	NNP
cord-310847-63gh2tg4	317	15	box	box	NN
cord-310847-63gh2tg4	317	16	,	,	,
cord-310847-63gh2tg4	317	17	the	the	DT
cord-310847-63gh2tg4	317	18	initial	initial	JJ
cord-310847-63gh2tg4	317	19	glycine	glycine	NN
cord-310847-63gh2tg4	317	20	and	and	CC
cord-310847-63gh2tg4	317	21	one	one	CD
cord-310847-63gh2tg4	317	22	or	or	CC
cord-310847-63gh2tg4	317	23	two	two	CD
cord-310847-63gh2tg4	317	24	glutamate	glutamate	NN
cord-310847-63gh2tg4	317	25	residues	residue	NNS
cord-310847-63gh2tg4	317	26	,	,	,
cord-310847-63gh2tg4	317	27	together	together	RB
cord-310847-63gh2tg4	317	28	with	with	IN
cord-310847-63gh2tg4	317	29	a	a	DT
cord-310847-63gh2tg4	317	30	remote	remote	JJ
cord-310847-63gh2tg4	317	31	glutamate	glutamate	NN
cord-310847-63gh2tg4	317	32	or	or	CC
cord-310847-63gh2tg4	317	33	glutamine	glutamine	NN
cord-310847-63gh2tg4	317	34	ligand	ligand	NN
cord-310847-63gh2tg4	317	35	located	locate	VBN
cord-310847-63gh2tg4	317	36	outside	outside	IN
cord-310847-63gh2tg4	317	37	the	the	DT
cord-310847-63gh2tg4	317	38	Nudix	Nudix	NNP
cord-310847-63gh2tg4	317	39	box	box	NN
cord-310847-63gh2tg4	317	40	.	.	.
cord-310847-63gh2tg4	318	1	111	111	CD
cord-310847-63gh2tg4	318	2	Glutamic	Glutamic	NNP
cord-310847-63gh2tg4	318	3	acids	acid	NNS
cord-310847-63gh2tg4	318	4	at	at	IN
cord-310847-63gh2tg4	318	5	various	various	JJ
cord-310847-63gh2tg4	318	6	binding	binding	NN
cord-310847-63gh2tg4	318	7	sites	site	NNS
cord-310847-63gh2tg4	318	8	.	.	.
cord-310847-63gh2tg4	319	1	Hemopexin	Hemopexin	NNP
cord-310847-63gh2tg4	319	2	is	be	VBZ
cord-310847-63gh2tg4	319	3	an	an	DT
cord-310847-63gh2tg4	319	4	important	important	JJ
cord-310847-63gh2tg4	319	5	multifunctional	multifunctional	JJ
cord-310847-63gh2tg4	319	6	plasma	plasma	NN
cord-310847-63gh2tg4	319	7	protein	protein	NN
cord-310847-63gh2tg4	319	8	involved	involve	VBN
cord-310847-63gh2tg4	319	9	in	in	IN
cord-310847-63gh2tg4	319	10	the	the	DT
cord-310847-63gh2tg4	319	11	sequestering	sequestering	NN
cord-310847-63gh2tg4	319	12	of	of	IN
cord-310847-63gh2tg4	319	13	heme	heme	NN
cord-310847-63gh2tg4	319	14	released	release	VBN
cord-310847-63gh2tg4	319	15	into	into	IN
cord-310847-63gh2tg4	319	16	the	the	DT
cord-310847-63gh2tg4	319	17	plasma	plasma	NN
cord-310847-63gh2tg4	319	18	from	from	IN
cord-310847-63gh2tg4	319	19	hemoglobin	hemoglobin	NN
cord-310847-63gh2tg4	319	20	and	and	CC
cord-310847-63gh2tg4	319	21	myoglobin	myoglobin	NN
cord-310847-63gh2tg4	319	22	as	as	IN
cord-310847-63gh2tg4	319	23	the	the	DT
cord-310847-63gh2tg4	319	24	result	result	NN
cord-310847-63gh2tg4	319	25	of	of	IN
cord-310847-63gh2tg4	319	26	intravascular	intravascular	JJ
cord-310847-63gh2tg4	319	27	or	or	CC
cord-310847-63gh2tg4	319	28	extravascular	extravascular	JJ
cord-310847-63gh2tg4	319	29	hemolysis	hemolysis	NN
cord-310847-63gh2tg4	319	30	and	and	CC
cord-310847-63gh2tg4	319	31	due	due	IN
cord-310847-63gh2tg4	319	32	to	to	IN
cord-310847-63gh2tg4	319	33	skeletal	skeletal	JJ
cord-310847-63gh2tg4	319	34	muscle	muscle	NN
cord-310847-63gh2tg4	319	35	trauma	trauma	NN
cord-310847-63gh2tg4	319	36	or	or	CC
cord-310847-63gh2tg4	319	37	neuromuscular	neuromuscular	JJ
cord-310847-63gh2tg4	319	38	disease	disease	NN
cord-310847-63gh2tg4	319	39	.	.	.
cord-310847-63gh2tg4	320	1	It	-PRON-	PRP
cord-310847-63gh2tg4	320	2	also	also	RB
cord-310847-63gh2tg4	320	3	possesses	possess	VBZ
cord-310847-63gh2tg4	320	4	hyaluronidase	hyaluronidase	NN
cord-310847-63gh2tg4	320	5	activity	activity	NN
cord-310847-63gh2tg4	320	6	,	,	,
cord-310847-63gh2tg4	320	7	serine	serine	NN
cord-310847-63gh2tg4	320	8	protease	protease	NN
cord-310847-63gh2tg4	320	9	activity	activity	NN
cord-310847-63gh2tg4	320	10	,	,	,
cord-310847-63gh2tg4	320	11	pro	pro	JJ
cord-310847-63gh2tg4	320	12	-	-	JJ
cord-310847-63gh2tg4	320	13	inflammatory	inflammatory	JJ
cord-310847-63gh2tg4	320	14	and	and	CC
cord-310847-63gh2tg4	320	15	anti	anti	JJ
cord-310847-63gh2tg4	320	16	-	-	JJ
cord-310847-63gh2tg4	320	17	inflammatory	inflammatory	JJ
cord-310847-63gh2tg4	320	18	activity	activity	NN
cord-310847-63gh2tg4	320	19	and	and	CC
cord-310847-63gh2tg4	320	20	is	be	VBZ
cord-310847-63gh2tg4	320	21	involved	involve	VBN
cord-310847-63gh2tg4	320	22	in	in	IN
cord-310847-63gh2tg4	320	23	the	the	DT
cord-310847-63gh2tg4	320	24	suppression	suppression	NN
cord-310847-63gh2tg4	320	25	of	of	IN
cord-310847-63gh2tg4	320	26	lymphocyte	lymphocyte	NN
cord-310847-63gh2tg4	320	27	necrosis	necrosis	NN
cord-310847-63gh2tg4	320	28	,	,	,
cord-310847-63gh2tg4	320	29	inhibition	inhibition	NN
cord-310847-63gh2tg4	320	30	of	of	IN
cord-310847-63gh2tg4	320	31	cellular	cellular	JJ
cord-310847-63gh2tg4	320	32	adhesion	adhesion	NN
cord-310847-63gh2tg4	320	33	,	,	,
cord-310847-63gh2tg4	320	34	and	and	CC
cord-310847-63gh2tg4	320	35	binding	binding	NN
cord-310847-63gh2tg4	320	36	of	of	IN
cord-310847-63gh2tg4	320	37	divalent	divalent	JJ
cord-310847-63gh2tg4	320	38	metal	metal	NN
cord-310847-63gh2tg4	320	39	ions	ion	NNS
cord-310847-63gh2tg4	320	40	.	.	.
cord-310847-63gh2tg4	321	1	Finally	finally	RB
cord-310847-63gh2tg4	321	2	,	,	,
cord-310847-63gh2tg4	321	3	hemopexin	hemopexin	NNP
cord-310847-63gh2tg4	321	4	possesses	possess	VBZ
cord-310847-63gh2tg4	321	5	two	two	CD
cord-310847-63gh2tg4	321	6	highly	highly	RB
cord-310847-63gh2tg4	321	7	exposed	expose	VBN
cord-310847-63gh2tg4	321	8	Arg	arg	NN
cord-310847-63gh2tg4	321	9	-	-	HYPH
cord-310847-63gh2tg4	321	10	Gly	Gly	NNP
cord-310847-63gh2tg4	321	11	-	-	HYPH
cord-310847-63gh2tg4	321	12	Glu	Glu	NNP
cord-310847-63gh2tg4	321	13	sequences	sequence	NNS
cord-310847-63gh2tg4	321	14	that	that	WDT
cord-310847-63gh2tg4	321	15	may	may	MD
cord-310847-63gh2tg4	321	16	promote	promote	VB
cord-310847-63gh2tg4	321	17	interaction	interaction	NN
cord-310847-63gh2tg4	321	18	with	with	IN
cord-310847-63gh2tg4	321	19	cell	cell	NN
cord-310847-63gh2tg4	321	20	surfaces	surface	NNS
cord-310847-63gh2tg4	321	21	.	.	.
cord-310847-63gh2tg4	322	1	112	112	CD
cord-310847-63gh2tg4	322	2	Glutamic	glutamic	NN
cord-310847-63gh2tg4	322	3	acid	acid	NN
cord-310847-63gh2tg4	322	4	plays	play	VBZ
cord-310847-63gh2tg4	322	5	an	an	DT
cord-310847-63gh2tg4	322	6	important	important	JJ
cord-310847-63gh2tg4	322	7	role	role	NN
cord-310847-63gh2tg4	322	8	in	in	IN
cord-310847-63gh2tg4	322	9	defining	define	VBG
cord-310847-63gh2tg4	322	10	the	the	DT
cord-310847-63gh2tg4	322	11	retinal	retinal	JJ
cord-310847-63gh2tg4	322	12	binding	binding	NN
cord-310847-63gh2tg4	322	13	site	site	NN
cord-310847-63gh2tg4	322	14	geometry	geometry	NN
cord-310847-63gh2tg4	322	15	of	of	IN
cord-310847-63gh2tg4	322	16	rhodopsin	rhodopsin	NN
cord-310847-63gh2tg4	322	17	,	,	,
cord-310847-63gh2tg4	322	18	which	which	WDT
cord-310847-63gh2tg4	322	19	is	be	VBZ
cord-310847-63gh2tg4	322	20	the	the	DT
cord-310847-63gh2tg4	322	21	photoreceptor	photoreceptor	NN
cord-310847-63gh2tg4	322	22	in	in	IN
cord-310847-63gh2tg4	322	23	vertebrate	vertebrate	JJ
cord-310847-63gh2tg4	322	24	rod	rod	NN
cord-310847-63gh2tg4	322	25	cells	cell	NNS
cord-310847-63gh2tg4	322	26	responsible	responsible	JJ
cord-310847-63gh2tg4	322	27	for	for	IN
cord-310847-63gh2tg4	322	28	vision	vision	NN
cord-310847-63gh2tg4	322	29	at	at	IN
cord-310847-63gh2tg4	322	30	low	low	JJ
cord-310847-63gh2tg4	322	31	light	light	JJ
cord-310847-63gh2tg4	322	32	intensities	intensity	NNS
cord-310847-63gh2tg4	322	33	.	.	.
cord-310847-63gh2tg4	323	1	11-cis	11-cis	CD
cord-310847-63gh2tg4	323	2	-	-	HYPH
cord-310847-63gh2tg4	323	3	retinal	retinal	NN
cord-310847-63gh2tg4	323	4	is	be	VBZ
cord-310847-63gh2tg4	323	5	the	the	DT
cord-310847-63gh2tg4	323	6	photoreactive	photoreactive	JJ
cord-310847-63gh2tg4	323	7	chromophore	chromophore	NN
cord-310847-63gh2tg4	323	8	located	locate	VBN
cord-310847-63gh2tg4	323	9	in	in	IN
cord-310847-63gh2tg4	323	10	the	the	DT
cord-310847-63gh2tg4	323	11	interior	interior	NN
cord-310847-63gh2tg4	323	12	of	of	IN
cord-310847-63gh2tg4	323	13	the	the	DT
cord-310847-63gh2tg4	323	14	protein	protein	NN
cord-310847-63gh2tg4	323	15	where	where	WRB
cord-310847-63gh2tg4	323	16	it	-PRON-	PRP
cord-310847-63gh2tg4	323	17	is	be	VBZ
cord-310847-63gh2tg4	323	18	covalently	covalently	RB
cord-310847-63gh2tg4	323	19	attached	attach	VBN
cord-310847-63gh2tg4	323	20	to	to	IN
cord-310847-63gh2tg4	323	21	a	a	DT
cord-310847-63gh2tg4	323	22	lysine	lysine	NN
cord-310847-63gh2tg4	323	23	side	side	NN
cord-310847-63gh2tg4	323	24	chain	chain	NN
cord-310847-63gh2tg4	323	25	through	through	IN
cord-310847-63gh2tg4	323	26	a	a	DT
cord-310847-63gh2tg4	323	27	protonated	protonated	JJ
cord-310847-63gh2tg4	323	28	Schiff	Schiff	NNP
cord-310847-63gh2tg4	323	29	base	base	NN
cord-310847-63gh2tg4	323	30	(	(	-LRB-
cord-310847-63gh2tg4	323	31	PSB	PSB	NNP
cord-310847-63gh2tg4	323	32	)	)	-RRB-
cord-310847-63gh2tg4	323	33	linkage	linkage	NN
cord-310847-63gh2tg4	323	34	.	.	.
cord-310847-63gh2tg4	324	1	113	113	CD
cord-310847-63gh2tg4	325	1	Based	base	VBN
cord-310847-63gh2tg4	325	2	on	on	IN
cord-310847-63gh2tg4	325	3	the	the	DT
cord-310847-63gh2tg4	325	4	13	13	CD
cord-310847-63gh2tg4	325	5	C	C	NNP
cord-310847-63gh2tg4	325	6	-	-	HYPH
cord-310847-63gh2tg4	325	7	NMR	NMR	NNP
cord-310847-63gh2tg4	325	8	chemical	chemical	NN
cord-310847-63gh2tg4	325	9	shift	shift	NN
cord-310847-63gh2tg4	325	10	data	datum	NNS
cord-310847-63gh2tg4	325	11	,	,	,
cord-310847-63gh2tg4	325	12	it	-PRON-	PRP
cord-310847-63gh2tg4	325	13	was	be	VBD
cord-310847-63gh2tg4	325	14	concluded	conclude	VBN
cord-310847-63gh2tg4	325	15	that	that	IN
cord-310847-63gh2tg4	325	16	Glu113	glu113	CD
cord-310847-63gh2tg4	325	17	of	of	IN
cord-310847-63gh2tg4	325	18	rhodopsin	rhodopsin	NN
cord-310847-63gh2tg4	325	19	is	be	VBZ
cord-310847-63gh2tg4	325	20	involved	involve	VBN
cord-310847-63gh2tg4	325	21	in	in	IN
cord-310847-63gh2tg4	325	22	charge	charge	NN
cord-310847-63gh2tg4	325	23	interactions	interaction	NNS
cord-310847-63gh2tg4	325	24	with	with	IN
cord-310847-63gh2tg4	325	25	the	the	DT
cord-310847-63gh2tg4	325	26	retinal	retinal	JJ
cord-310847-63gh2tg4	325	27	PSB	PSB	NNP
cord-310847-63gh2tg4	325	28	,	,	,
cord-310847-63gh2tg4	325	29	which	which	WDT
cord-310847-63gh2tg4	325	30	are	be	VBP
cord-310847-63gh2tg4	325	31	crucial	crucial	JJ
cord-310847-63gh2tg4	325	32	for	for	IN
cord-310847-63gh2tg4	325	33	maintaining	maintain	VBG
cord-310847-63gh2tg4	325	34	rhodopsin	rhodopsin	NN
cord-310847-63gh2tg4	325	35	in	in	IN
cord-310847-63gh2tg4	325	36	the	the	DT
cord-310847-63gh2tg4	325	37	inactive	inactive	JJ
cord-310847-63gh2tg4	325	38	state	state	NN
cord-310847-63gh2tg4	325	39	in	in	IN
cord-310847-63gh2tg4	325	40	the	the	DT
cord-310847-63gh2tg4	325	41	dark	dark	NN
cord-310847-63gh2tg4	325	42	and	and	CC
cord-310847-63gh2tg4	325	43	whose	whose	WP$
cord-310847-63gh2tg4	325	44	breaking	breaking	NN
cord-310847-63gh2tg4	325	45	leads	lead	VBZ
cord-310847-63gh2tg4	325	46	to	to	IN
cord-310847-63gh2tg4	325	47	the	the	DT
cord-310847-63gh2tg4	325	48	protein	protein	NN
cord-310847-63gh2tg4	325	49	activation	activation	NN
cord-310847-63gh2tg4	325	50	.	.	.
cord-310847-63gh2tg4	326	1	113	113	CD
cord-310847-63gh2tg4	327	1	A	a	DT
cord-310847-63gh2tg4	327	2	centrally	centrally	RB
cord-310847-63gh2tg4	327	3	located	locate	VBN
cord-310847-63gh2tg4	327	4	glutamic	glutamic	NN
cord-310847-63gh2tg4	327	5	acid	acid	NN
cord-310847-63gh2tg4	327	6	residue	residue	NN
cord-310847-63gh2tg4	327	7	in	in	IN
cord-310847-63gh2tg4	327	8	position	position	NN
cord-310847-63gh2tg4	327	9	6	6	CD
cord-310847-63gh2tg4	327	10	of	of	IN
cord-310847-63gh2tg4	327	11	transmembrane	transmembrane	NN
cord-310847-63gh2tg4	327	12	segment	segment	NN
cord-310847-63gh2tg4	327	13	VII	VII	NNP
cord-310847-63gh2tg4	327	14	of	of	IN
cord-310847-63gh2tg4	327	15	the	the	DT
cord-310847-63gh2tg4	327	16	main	main	JJ
cord-310847-63gh2tg4	327	17	ligand	ligand	NN
cord-310847-63gh2tg4	327	18	-	-	HYPH
cord-310847-63gh2tg4	327	19	binding	bind	VBG
cord-310847-63gh2tg4	327	20	crevice	crevice	NN
cord-310847-63gh2tg4	327	21	of	of	IN
cord-310847-63gh2tg4	327	22	the	the	DT
cord-310847-63gh2tg4	327	23	chemokine	chemokine	NN
cord-310847-63gh2tg4	327	24	7TM	7tm	CD
cord-310847-63gh2tg4	327	25	receptors	receptor	NNS
cord-310847-63gh2tg4	327	26	(	(	-LRB-
cord-310847-63gh2tg4	327	27	GluVII:06	gluvii:06	NN
cord-310847-63gh2tg4	327	28	)	)	-RRB-
cord-310847-63gh2tg4	327	29	is	be	VBZ
cord-310847-63gh2tg4	327	30	crucial	crucial	JJ
cord-310847-63gh2tg4	327	31	for	for	IN
cord-310847-63gh2tg4	327	32	recognition	recognition	NN
cord-310847-63gh2tg4	327	33	and	and	CC
cord-310847-63gh2tg4	327	34	binding	binding	NN
cord-310847-63gh2tg4	327	35	of	of	IN
cord-310847-63gh2tg4	327	36	small	small	JJ
cord-310847-63gh2tg4	327	37	molecule	molecule	NN
cord-310847-63gh2tg4	327	38	non	non	JJ
cord-310847-63gh2tg4	327	39	-	-	JJ
cord-310847-63gh2tg4	327	40	peptide	peptide	JJ
cord-310847-63gh2tg4	327	41	ligands	ligand	NNS
cord-310847-63gh2tg4	327	42	that	that	WDT
cord-310847-63gh2tg4	327	43	contain	contain	VBP
cord-310847-63gh2tg4	327	44	one	one	CD
cord-310847-63gh2tg4	327	45	or	or	CC
cord-310847-63gh2tg4	327	46	two	two	CD
cord-310847-63gh2tg4	327	47	centrally	centrally	RB
cord-310847-63gh2tg4	327	48	located	locate	VBN
cord-310847-63gh2tg4	327	49	,	,	,
cord-310847-63gh2tg4	327	50	positively	positively	RB
cord-310847-63gh2tg4	327	51	charged	charge	VBN
cord-310847-63gh2tg4	327	52	nitrogen	nitrogen	NN
cord-310847-63gh2tg4	327	53	atoms	atom	NNS
cord-310847-63gh2tg4	327	54	and	and	CC
cord-310847-63gh2tg4	327	55	are	be	VBP
cord-310847-63gh2tg4	327	56	characterized	characterize	VBN
cord-310847-63gh2tg4	327	57	by	by	IN
cord-310847-63gh2tg4	327	58	relatively	relatively	RB
cord-310847-63gh2tg4	327	59	similar	similar	JJ
cord-310847-63gh2tg4	327	60	elongated	elongated	JJ
cord-310847-63gh2tg4	327	61	overall	overall	JJ
cord-310847-63gh2tg4	327	62	structure	structure	NN
cord-310847-63gh2tg4	327	63	with	with	IN
cord-310847-63gh2tg4	327	64	terminal	terminal	JJ
cord-310847-63gh2tg4	327	65	aromatic	aromatic	JJ
cord-310847-63gh2tg4	327	66	moieties	moiety	NNS
cord-310847-63gh2tg4	327	67	.	.	.
cord-310847-63gh2tg4	328	1	114	114	CD
cord-310847-63gh2tg4	329	1	Furthermore	furthermore	RB
cord-310847-63gh2tg4	329	2	,	,	,
cord-310847-63gh2tg4	329	3	since	since	IN
cord-310847-63gh2tg4	329	4	this	this	DT
cord-310847-63gh2tg4	329	5	GluVII:06	gluvii:06	NN
cord-310847-63gh2tg4	329	6	is	be	VBZ
cord-310847-63gh2tg4	329	7	crucial	crucial	JJ
cord-310847-63gh2tg4	329	8	for	for	IN
cord-310847-63gh2tg4	329	9	the	the	DT
cord-310847-63gh2tg4	329	10	binding	binding	NN
cord-310847-63gh2tg4	329	11	and	and	CC
cord-310847-63gh2tg4	329	12	hence	hence	RB
cord-310847-63gh2tg4	329	13	the	the	DT
cord-310847-63gh2tg4	329	14	function	function	NN
cord-310847-63gh2tg4	329	15	of	of	IN
cord-310847-63gh2tg4	329	16	a	a	DT
cord-310847-63gh2tg4	329	17	number	number	NN
cord-310847-63gh2tg4	329	18	of	of	IN
cord-310847-63gh2tg4	329	19	non	non	JJ
cord-310847-63gh2tg4	329	20	-	-	JJ
cord-310847-63gh2tg4	329	21	peptide	peptide	JJ
cord-310847-63gh2tg4	329	22	ligands	ligand	NNS
cord-310847-63gh2tg4	329	23	in	in	IN
cord-310847-63gh2tg4	329	24	several	several	JJ
cord-310847-63gh2tg4	329	25	chemokine	chemokine	NN
cord-310847-63gh2tg4	329	26	receptors	receptor	NNS
cord-310847-63gh2tg4	329	27	,	,	,
cord-310847-63gh2tg4	329	28	such	such	JJ
cord-310847-63gh2tg4	329	29	as	as	IN
cord-310847-63gh2tg4	329	30	the	the	DT
cord-310847-63gh2tg4	329	31	CCR1	CCR1	NNP
cord-310847-63gh2tg4	329	32	,	,	,
cord-310847-63gh2tg4	329	33	CCR2	CCR2	NNP
cord-310847-63gh2tg4	329	34	and	and	CC
cord-310847-63gh2tg4	329	35	CCR5	CCR5	NNP
cord-310847-63gh2tg4	329	36	receptors	receptor	NNS
cord-310847-63gh2tg4	329	37	,	,	,
cord-310847-63gh2tg4	329	38	it	-PRON-	PRP
cord-310847-63gh2tg4	329	39	serves	serve	VBZ
cord-310847-63gh2tg4	329	40	as	as	IN
cord-310847-63gh2tg4	329	41	a	a	DT
cord-310847-63gh2tg4	329	42	selective	selective	JJ
cord-310847-63gh2tg4	329	43	anchor	anchor	NN
cord-310847-63gh2tg4	329	44	point	point	NN
cord-310847-63gh2tg4	329	45	for	for	IN
cord-310847-63gh2tg4	329	46	the	the	DT
cord-310847-63gh2tg4	329	47	centrally	centrally	RB
cord-310847-63gh2tg4	329	48	located	locate	VBN
cord-310847-63gh2tg4	329	49	,	,	,
cord-310847-63gh2tg4	329	50	positively	positively	RB
cord-310847-63gh2tg4	329	51	charged	charge	VBN
cord-310847-63gh2tg4	329	52	nitrogen	nitrogen	NN
cord-310847-63gh2tg4	329	53	of	of	IN
cord-310847-63gh2tg4	329	54	the	the	DT
cord-310847-63gh2tg4	329	55	small	small	JJ
cord-310847-63gh2tg4	329	56	molecule	molecule	NN
cord-310847-63gh2tg4	329	57	ligands	ligand	NNS
cord-310847-63gh2tg4	329	58	.	.	.
cord-310847-63gh2tg4	330	1	114	114	CD
cord-310847-63gh2tg4	330	2	Glutamic	glutamic	NN
cord-310847-63gh2tg4	330	3	acid	acid	NN
cord-310847-63gh2tg4	330	4	and	and	CC
cord-310847-63gh2tg4	330	5	metal	metal	NN
cord-310847-63gh2tg4	330	6	binding	binding	NN
cord-310847-63gh2tg4	330	7	.	.	.
cord-310847-63gh2tg4	331	1	The	the	DT
cord-310847-63gh2tg4	331	2	role	role	NN
cord-310847-63gh2tg4	331	3	of	of	IN
cord-310847-63gh2tg4	331	4	glutamic	glutamic	NN
cord-310847-63gh2tg4	331	5	acid	acid	NN
cord-310847-63gh2tg4	331	6	residues	residue	NNS
cord-310847-63gh2tg4	331	7	in	in	IN
cord-310847-63gh2tg4	331	8	coordination	coordination	NN
cord-310847-63gh2tg4	331	9	of	of	IN
cord-310847-63gh2tg4	331	10	various	various	JJ
cord-310847-63gh2tg4	331	11	metal	metal	NN
cord-310847-63gh2tg4	331	12	ions	ion	NNS
cord-310847-63gh2tg4	331	13	was	be	VBD
cord-310847-63gh2tg4	331	14	already	already	RB
cord-310847-63gh2tg4	331	15	emphasized	emphasize	VBN
cord-310847-63gh2tg4	331	16	in	in	IN
cord-310847-63gh2tg4	331	17	sections	section	NNS
cord-310847-63gh2tg4	331	18	discussing	discuss	VBG
cord-310847-63gh2tg4	331	19	ion	ion	NN
cord-310847-63gh2tg4	331	20	channels	channel	NNS
cord-310847-63gh2tg4	331	21	.	.	.
cord-310847-63gh2tg4	332	1	A	a	DT
cord-310847-63gh2tg4	332	2	few	few	JJ
cord-310847-63gh2tg4	332	3	other	other	JJ
cord-310847-63gh2tg4	332	4	illustrative	illustrative	JJ
cord-310847-63gh2tg4	332	5	examples	example	NNS
cord-310847-63gh2tg4	332	6	are	be	VBP
cord-310847-63gh2tg4	332	7	listed	list	VBN
cord-310847-63gh2tg4	332	8	below	below	RB
cord-310847-63gh2tg4	332	9	.	.	.
cord-310847-63gh2tg4	333	1	Based	base	VBN
cord-310847-63gh2tg4	333	2	on	on	IN
cord-310847-63gh2tg4	333	3	the	the	DT
cord-310847-63gh2tg4	333	4	analysis	analysis	NN
cord-310847-63gh2tg4	333	5	of	of	IN
cord-310847-63gh2tg4	333	6	the	the	DT
cord-310847-63gh2tg4	333	7	complexes	complex	NNS
cord-310847-63gh2tg4	333	8	formed	form	VBN
cord-310847-63gh2tg4	333	9	between	between	IN
cord-310847-63gh2tg4	333	10	integrins	integrin	NNS
cord-310847-63gh2tg4	333	11	(	(	-LRB-
cord-310847-63gh2tg4	333	12	which	which	WDT
cord-310847-63gh2tg4	333	13	are	be	VBP
cord-310847-63gh2tg4	333	14	central	central	JJ
cord-310847-63gh2tg4	333	15	molecules	molecule	NNS
cord-310847-63gh2tg4	333	16	in	in	IN
cord-310847-63gh2tg4	333	17	the	the	DT
cord-310847-63gh2tg4	333	18	adhesion	adhesion	NN
cord-310847-63gh2tg4	333	19	processes	process	NNS
cord-310847-63gh2tg4	333	20	that	that	WDT
cord-310847-63gh2tg4	333	21	mediate	mediate	VBP
cord-310847-63gh2tg4	333	22	cell	cell	NN
cord-310847-63gh2tg4	333	23	-	-	HYPH
cord-310847-63gh2tg4	333	24	cell	cell	NN
cord-310847-63gh2tg4	333	25	and	and	CC
cord-310847-63gh2tg4	333	26	cell	cell	NN
cord-310847-63gh2tg4	333	27	-	-	HYPH
cord-310847-63gh2tg4	333	28	extracellular	extracellular	JJ
cord-310847-63gh2tg4	333	29	group	group	NN
cord-310847-63gh2tg4	333	30	giving	give	VBG
cord-310847-63gh2tg4	333	31	rise	rise	NN
cord-310847-63gh2tg4	333	32	to	to	IN
cord-310847-63gh2tg4	333	33	the	the	DT
cord-310847-63gh2tg4	333	34	pyrrolidone	pyrrolidone	JJ
cord-310847-63gh2tg4	333	35	carboxylic	carboxylic	NNP
cord-310847-63gh2tg4	333	36	acid	acid	NN
cord-310847-63gh2tg4	333	37	(	(	-LRB-
cord-310847-63gh2tg4	333	38	pyro	pyro	NN
cord-310847-63gh2tg4	333	39	-	-	HYPH
cord-310847-63gh2tg4	333	40	Glu	Glu	NNP
cord-310847-63gh2tg4	333	41	)	)	-RRB-
cord-310847-63gh2tg4	333	42	.	.	.
cord-310847-63gh2tg4	334	1	However	however	RB
cord-310847-63gh2tg4	334	2	,	,	,
cord-310847-63gh2tg4	334	3	it	-PRON-	PRP
cord-310847-63gh2tg4	334	4	was	be	VBD
cord-310847-63gh2tg4	334	5	emphasized	emphasize	VBN
cord-310847-63gh2tg4	334	6	that	that	IN
cord-310847-63gh2tg4	334	7	pyro	pyro	NN
cord-310847-63gh2tg4	334	8	-	-	HYPH
cord-310847-63gh2tg4	334	9	Glu	Glu	NNP
cord-310847-63gh2tg4	334	10	is	be	VBZ
cord-310847-63gh2tg4	334	11	exclusively	exclusively	RB
cord-310847-63gh2tg4	334	12	found	find	VBN
cord-310847-63gh2tg4	334	13	at	at	IN
cord-310847-63gh2tg4	334	14	the	the	DT
cord-310847-63gh2tg4	334	15	N	n	CD
cord-310847-63gh2tg4	334	16	-	-	HYPH
cord-310847-63gh2tg4	334	17	terminal	terminal	JJ
cord-310847-63gh2tg4	334	18	end	end	NN
cord-310847-63gh2tg4	334	19	of	of	IN
cord-310847-63gh2tg4	334	20	the	the	DT
cord-310847-63gh2tg4	334	21	thermal	thermal	JJ
cord-310847-63gh2tg4	334	22	polymers	polymer	NNS
cord-310847-63gh2tg4	334	23	when	when	WRB
cord-310847-63gh2tg4	334	24	glutamic	glutamic	NN
cord-310847-63gh2tg4	334	25	acid	acid	NN
cord-310847-63gh2tg4	334	26	is	be	VBZ
cord-310847-63gh2tg4	334	27	a	a	DT
cord-310847-63gh2tg4	334	28	predominant	predominant	JJ
cord-310847-63gh2tg4	334	29	amino	amino	NN
cord-310847-63gh2tg4	334	30	acid	acid	NN
cord-310847-63gh2tg4	334	31	in	in	IN
cord-310847-63gh2tg4	334	32	a	a	DT
cord-310847-63gh2tg4	334	33	mixture	mixture	NN
cord-310847-63gh2tg4	334	34	of	of	IN
cord-310847-63gh2tg4	334	35	amino	amino	JJ
cord-310847-63gh2tg4	334	36	acids	acid	NNS
cord-310847-63gh2tg4	334	37	subjected	subject	VBN
cord-310847-63gh2tg4	334	38	to	to	IN
cord-310847-63gh2tg4	334	39	thermal	thermal	JJ
cord-310847-63gh2tg4	334	40	polymerization	polymerization	NN
cord-310847-63gh2tg4	334	41	.	.	.
cord-310847-63gh2tg4	335	1	129	129	CD
cord-310847-63gh2tg4	336	1	Another	another	DT
cord-310847-63gh2tg4	336	2	important	important	JJ
cord-310847-63gh2tg4	336	3	glutamic	glutamic	NN
cord-310847-63gh2tg4	336	4	acid	acid	NN
cord-310847-63gh2tg4	336	5	-	-	HYPH
cord-310847-63gh2tg4	336	6	based	base	VBN
cord-310847-63gh2tg4	336	7	PTM	PTM	NNP
cord-310847-63gh2tg4	336	8	is	be	VBZ
cord-310847-63gh2tg4	336	9	gammacarboxylation	gammacarboxylation	NN
cord-310847-63gh2tg4	336	10	catalyzed	catalyze	VBN
cord-310847-63gh2tg4	336	11	by	by	IN
cord-310847-63gh2tg4	336	12	the	the	DT
cord-310847-63gh2tg4	336	13	vitamin	vitamin	NN
cord-310847-63gh2tg4	336	14	K	k	NN
cord-310847-63gh2tg4	336	15	-	-	HYPH
cord-310847-63gh2tg4	336	16	dependent	dependent	JJ
cord-310847-63gh2tg4	336	17	carboxylase	carboxylase	NN
cord-310847-63gh2tg4	336	18	that	that	WDT
cord-310847-63gh2tg4	336	19	transforms	transform	VBZ
cord-310847-63gh2tg4	336	20	specific	specific	JJ
cord-310847-63gh2tg4	336	21	glutamate	glutamate	NN
cord-310847-63gh2tg4	336	22	residues	residue	NNS
cord-310847-63gh2tg4	336	23	in	in	IN
cord-310847-63gh2tg4	336	24	proteins	protein	NNS
cord-310847-63gh2tg4	336	25	to	to	IN
cord-310847-63gh2tg4	336	26	gammacarboxy	gammacarboxy	VB
cord-310847-63gh2tg4	336	27	glutamic	glutamic	NN
cord-310847-63gh2tg4	336	28	acid	acid	NN
cord-310847-63gh2tg4	336	29	(	(	-LRB-
cord-310847-63gh2tg4	336	30	Gla	Gla	NNP
cord-310847-63gh2tg4	336	31	)	)	-RRB-
cord-310847-63gh2tg4	336	32	in	in	IN
cord-310847-63gh2tg4	336	33	the	the	DT
cord-310847-63gh2tg4	336	34	presence	presence	NN
cord-310847-63gh2tg4	336	35	of	of	IN
cord-310847-63gh2tg4	336	36	reduced	reduce	VBN
cord-310847-63gh2tg4	336	37	vitamin	vitamin	NN
cord-310847-63gh2tg4	336	38	K	k	NN
cord-310847-63gh2tg4	336	39	,	,	,
cord-310847-63gh2tg4	336	40	molecular	molecular	JJ
cord-310847-63gh2tg4	336	41	oxygen	oxygen	NN
cord-310847-63gh2tg4	336	42	and	and	CC
cord-310847-63gh2tg4	336	43	carbon	carbon	NN
cord-310847-63gh2tg4	336	44	dioxide	dioxide	NN
cord-310847-63gh2tg4	336	45	.	.	.
cord-310847-63gh2tg4	337	1	130	130	CD
cord-310847-63gh2tg4	338	1	This	this	DT
cord-310847-63gh2tg4	338	2	modification	modification	NN
cord-310847-63gh2tg4	338	3	is	be	VBZ
cord-310847-63gh2tg4	338	4	widely	widely	RB
cord-310847-63gh2tg4	338	5	distributed	distribute	VBN
cord-310847-63gh2tg4	338	6	in	in	IN
cord-310847-63gh2tg4	338	7	the	the	DT
cord-310847-63gh2tg4	338	8	animal	animal	NN
cord-310847-63gh2tg4	338	9	kingdom	kingdom	NN
cord-310847-63gh2tg4	338	10	and	and	CC
cord-310847-63gh2tg4	338	11	has	have	VBZ
cord-310847-63gh2tg4	338	12	a	a	DT
cord-310847-63gh2tg4	338	13	wide	wide	JJ
cord-310847-63gh2tg4	338	14	range	range	NN
cord-310847-63gh2tg4	338	15	of	of	IN
cord-310847-63gh2tg4	338	16	physiological	physiological	JJ
cord-310847-63gh2tg4	338	17	implications	implication	NNS
cord-310847-63gh2tg4	338	18	,	,	,
cord-310847-63gh2tg4	338	19	such	such	JJ
cord-310847-63gh2tg4	338	20	as	as	IN
cord-310847-63gh2tg4	338	21	hemostasis	hemostasis	NN
cord-310847-63gh2tg4	338	22	,	,	,
cord-310847-63gh2tg4	338	23	bone	bone	NN
cord-310847-63gh2tg4	338	24	calcification	calcification	NN
cord-310847-63gh2tg4	338	25	and	and	CC
cord-310847-63gh2tg4	338	26	signal	signal	NN
cord-310847-63gh2tg4	338	27	transduction	transduction	NN
cord-310847-63gh2tg4	338	28	.	.	.
cord-310847-63gh2tg4	339	1	130	130	CD
cord-310847-63gh2tg4	340	1	In	in	IN
cord-310847-63gh2tg4	340	2	addition	addition	NN
cord-310847-63gh2tg4	340	3	to	to	TO
cord-310847-63gh2tg4	340	4	be	be	VB
cord-310847-63gh2tg4	340	5	a	a	DT
cord-310847-63gh2tg4	340	6	target	target	NN
cord-310847-63gh2tg4	340	7	for	for	IN
cord-310847-63gh2tg4	340	8	various	various	JJ
cord-310847-63gh2tg4	340	9	PTMs	ptm	NNS
cord-310847-63gh2tg4	340	10	,	,	,
cord-310847-63gh2tg4	340	11	glutamic	glutamic	NN
cord-310847-63gh2tg4	340	12	acid	acid	NN
cord-310847-63gh2tg4	340	13	itself	-PRON-	PRP
cord-310847-63gh2tg4	340	14	can	can	MD
cord-310847-63gh2tg4	340	15	be	be	VB
cord-310847-63gh2tg4	340	16	used	use	VBN
cord-310847-63gh2tg4	340	17	as	as	IN
cord-310847-63gh2tg4	340	18	an	an	DT
cord-310847-63gh2tg4	340	19	important	important	JJ
cord-310847-63gh2tg4	340	20	protein	protein	NN
cord-310847-63gh2tg4	340	21	modifier	modifier	NN
cord-310847-63gh2tg4	340	22	,	,	,
cord-310847-63gh2tg4	340	23	giving	give	VBG
cord-310847-63gh2tg4	340	24	raise	raise	NN
cord-310847-63gh2tg4	340	25	to	to	IN
cord-310847-63gh2tg4	340	26	polyglutamylation	polyglutamylation	NN
cord-310847-63gh2tg4	340	27	,	,	,
cord-310847-63gh2tg4	340	28	which	which	WDT
cord-310847-63gh2tg4	340	29	is	be	VBZ
cord-310847-63gh2tg4	340	30	a	a	DT
cord-310847-63gh2tg4	340	31	specific	specific	JJ
cord-310847-63gh2tg4	340	32	PTM	PTM	NNP
cord-310847-63gh2tg4	340	33	where	where	WRB
cord-310847-63gh2tg4	340	34	polyglutamate	polyglutamate	NNP
cord-310847-63gh2tg4	340	35	chains	chain	NNS
cord-310847-63gh2tg4	340	36	of	of	IN
cord-310847-63gh2tg4	340	37	variable	variable	JJ
cord-310847-63gh2tg4	340	38	lengths	length	NNS
cord-310847-63gh2tg4	340	39	are	be	VBP
cord-310847-63gh2tg4	340	40	added	add	VBN
cord-310847-63gh2tg4	340	41	to	to	IN
cord-310847-63gh2tg4	340	42	the	the	DT
cord-310847-63gh2tg4	340	43	modified	modify	VBN
cord-310847-63gh2tg4	340	44	protein	protein	NN
cord-310847-63gh2tg4	340	45	.	.	.
cord-310847-63gh2tg4	341	1	131	131	CD
cord-310847-63gh2tg4	341	2	Polyglutamylation	Polyglutamylation	NNP
cord-310847-63gh2tg4	341	3	is	be	VBZ
cord-310847-63gh2tg4	341	4	evolutionarily	evolutionarily	RB
cord-310847-63gh2tg4	341	5	conserved	conserve	VBN
cord-310847-63gh2tg4	341	6	and	and	CC
cord-310847-63gh2tg4	341	7	is	be	VBZ
cord-310847-63gh2tg4	341	8	commonly	commonly	RB
cord-310847-63gh2tg4	341	9	found	find	VBN
cord-310847-63gh2tg4	341	10	in	in	IN
cord-310847-63gh2tg4	341	11	the	the	DT
cord-310847-63gh2tg4	341	12	microtubule	microtubule	NN
cord-310847-63gh2tg4	341	13	(	(	-LRB-
cord-310847-63gh2tg4	341	14	MT	MT	NNP
cord-310847-63gh2tg4	341	15	)	)	-RRB-
cord-310847-63gh2tg4	341	16	building	building	NN
cord-310847-63gh2tg4	341	17	block	block	NN
cord-310847-63gh2tg4	341	18	,	,	,
cord-310847-63gh2tg4	341	19	tubulin	tubulin	NN
cord-310847-63gh2tg4	341	20	.	.	.
cord-310847-63gh2tg4	342	1	This	this	DT
cord-310847-63gh2tg4	342	2	PTM	PTM	NNP
cord-310847-63gh2tg4	342	3	,	,	,
cord-310847-63gh2tg4	342	4	being	be	VBG
cord-310847-63gh2tg4	342	5	primarily	primarily	RB
cord-310847-63gh2tg4	342	6	found	find	VBN
cord-310847-63gh2tg4	342	7	within	within	IN
cord-310847-63gh2tg4	342	8	the	the	DT
cord-310847-63gh2tg4	342	9	tubulin	tubulin	NN
cord-310847-63gh2tg4	342	10	C	c	NN
cord-310847-63gh2tg4	342	11	-	-	HYPH
cord-310847-63gh2tg4	342	12	terminal	terminal	NN
cord-310847-63gh2tg4	342	13	tail	tail	NN
cord-310847-63gh2tg4	342	14	that	that	WDT
cord-310847-63gh2tg4	342	15	participates	participate	VBZ
cord-310847-63gh2tg4	342	16	in	in	IN
cord-310847-63gh2tg4	342	17	binding	binding	NN
cord-310847-63gh2tg4	342	18	of	of	IN
cord-310847-63gh2tg4	342	19	many	many	JJ
cord-310847-63gh2tg4	342	20	structural	structural	JJ
cord-310847-63gh2tg4	342	21	and	and	CC
cord-310847-63gh2tg4	342	22	motor	motor	NN
cord-310847-63gh2tg4	342	23	MT	MT	NNP
cord-310847-63gh2tg4	342	24	-	-	HYPH
cord-310847-63gh2tg4	342	25	associated	associate	VBN
cord-310847-63gh2tg4	342	26	proteins	protein	NNS
cord-310847-63gh2tg4	342	27	,	,	,
cord-310847-63gh2tg4	342	28	is	be	VBZ
cord-310847-63gh2tg4	342	29	believed	believe	VBN
cord-310847-63gh2tg4	342	30	to	to	TO
cord-310847-63gh2tg4	342	31	be	be	VB
cord-310847-63gh2tg4	342	32	crucial	crucial	JJ
cord-310847-63gh2tg4	342	33	for	for	IN
cord-310847-63gh2tg4	342	34	the	the	DT
cord-310847-63gh2tg4	342	35	functional	functional	JJ
cord-310847-63gh2tg4	342	36	adaptation	adaptation	NN
cord-310847-63gh2tg4	342	37	of	of	IN
cord-310847-63gh2tg4	342	38	MTs	MTs	NNP
cord-310847-63gh2tg4	342	39	.	.	.
cord-310847-63gh2tg4	343	1	Polyglutamylation	Polyglutamylation	NNP
cord-310847-63gh2tg4	343	2	is	be	VBZ
cord-310847-63gh2tg4	343	3	catalyzed	catalyze	VBN
cord-310847-63gh2tg4	343	4	by	by	IN
cord-310847-63gh2tg4	343	5	a	a	DT
cord-310847-63gh2tg4	343	6	family	family	NN
cord-310847-63gh2tg4	343	7	of	of	IN
cord-310847-63gh2tg4	343	8	specific	specific	JJ
cord-310847-63gh2tg4	343	9	enzymes	enzyme	NNS
cord-310847-63gh2tg4	343	10	and	and	CC
cord-310847-63gh2tg4	343	11	in	in	IN
cord-310847-63gh2tg4	343	12	addition	addition	NN
cord-310847-63gh2tg4	343	13	to	to	IN
cord-310847-63gh2tg4	343	14	tubulin	tubulin	NN
cord-310847-63gh2tg4	343	15	can	can	MD
cord-310847-63gh2tg4	343	16	be	be	VB
cord-310847-63gh2tg4	343	17	found	find	VBN
cord-310847-63gh2tg4	343	18	in	in	IN
cord-310847-63gh2tg4	343	19	some	some	DT
cord-310847-63gh2tg4	343	20	other	other	JJ
cord-310847-63gh2tg4	343	21	proteins	protein	NNS
cord-310847-63gh2tg4	343	22	.	.	.
cord-310847-63gh2tg4	344	1	131	131	CD
cord-310847-63gh2tg4	344	2	High	high	JJ
cord-310847-63gh2tg4	344	3	content	content	NN
cord-310847-63gh2tg4	344	4	of	of	IN
cord-310847-63gh2tg4	344	5	charged	charge	VBN
cord-310847-63gh2tg4	344	6	residues	residue	NNS
cord-310847-63gh2tg4	344	7	is	be	VBZ
cord-310847-63gh2tg4	344	8	one	one	CD
cord-310847-63gh2tg4	344	9	of	of	IN
cord-310847-63gh2tg4	344	10	the	the	DT
cord-310847-63gh2tg4	344	11	tricks	trick	NNS
cord-310847-63gh2tg4	344	12	used	use	VBN
cord-310847-63gh2tg4	344	13	by	by	IN
cord-310847-63gh2tg4	344	14	Nature	Nature	NNP
cord-310847-63gh2tg4	344	15	to	to	TO
cord-310847-63gh2tg4	344	16	make	make	VB
cord-310847-63gh2tg4	344	17	stable	stable	JJ
cord-310847-63gh2tg4	344	18	proteins	protein	NNS
cord-310847-63gh2tg4	344	19	in	in	IN
cord-310847-63gh2tg4	344	20	thermophilic	thermophilic	JJ
cord-310847-63gh2tg4	344	21	and	and	CC
cord-310847-63gh2tg4	344	22	hyperthermophilic	hyperthermophilic	JJ
cord-310847-63gh2tg4	344	23	organisms	organism	NNS
cord-310847-63gh2tg4	344	24	.	.	.
cord-310847-63gh2tg4	345	1	132	132	CD
cord-310847-63gh2tg4	346	1	In	in	IN
cord-310847-63gh2tg4	346	2	fact	fact	NN
cord-310847-63gh2tg4	346	3	,	,	,
cord-310847-63gh2tg4	346	4	based	base	VBN
cord-310847-63gh2tg4	346	5	on	on	IN
cord-310847-63gh2tg4	346	6	the	the	DT
cord-310847-63gh2tg4	346	7	correspondence	correspondence	NN
cord-310847-63gh2tg4	346	8	analysis	analysis	NN
cord-310847-63gh2tg4	346	9	of	of	IN
cord-310847-63gh2tg4	346	10	the	the	DT
cord-310847-63gh2tg4	346	11	56	56	CD
cord-310847-63gh2tg4	346	12	completely	completely	RB
cord-310847-63gh2tg4	346	13	sequenced	sequence	VBN
cord-310847-63gh2tg4	346	14	genomes	genome	NNS
cord-310847-63gh2tg4	346	15	available	available	JJ
cord-310847-63gh2tg4	346	16	from	from	IN
cord-310847-63gh2tg4	346	17	the	the	DT
cord-310847-63gh2tg4	346	18	three	three	CD
cord-310847-63gh2tg4	346	19	domains	domain	NNS
cord-310847-63gh2tg4	346	20	of	of	IN
cord-310847-63gh2tg4	346	21	life	life	NN
cord-310847-63gh2tg4	346	22	(	(	-LRB-
cord-310847-63gh2tg4	346	23	seven	seven	CD
cord-310847-63gh2tg4	346	24	eukaryotes	eukaryote	NNS
cord-310847-63gh2tg4	346	25	,	,	,
cord-310847-63gh2tg4	346	26	14	14	CD
cord-310847-63gh2tg4	346	27	archaeal	archaeal	JJ
cord-310847-63gh2tg4	346	28	and	and	CC
cord-310847-63gh2tg4	346	29	35	35	CD
cord-310847-63gh2tg4	346	30	bacterial	bacterial	JJ
cord-310847-63gh2tg4	346	31	species	specie	NNS
cord-310847-63gh2tg4	346	32	)	)	-RRB-
cord-310847-63gh2tg4	346	33	it	-PRON-	PRP
cord-310847-63gh2tg4	346	34	has	have	VBZ
cord-310847-63gh2tg4	346	35	been	be	VBN
cord-310847-63gh2tg4	346	36	concluded	conclude	VBN
cord-310847-63gh2tg4	346	37	and	and	CC
cord-310847-63gh2tg4	346	38	the	the	DT
cord-310847-63gh2tg4	346	39	amino	amino	NN
cord-310847-63gh2tg4	346	40	acid	acid	NN
cord-310847-63gh2tg4	346	41	composition	composition	NN
cord-310847-63gh2tg4	346	42	permits	permit	VBZ
cord-310847-63gh2tg4	346	43	discrimination	discrimination	NN
cord-310847-63gh2tg4	346	44	between	between	IN
cord-310847-63gh2tg4	346	45	the	the	DT
cord-310847-63gh2tg4	346	46	three	three	CD
cord-310847-63gh2tg4	346	47	known	know	VBN
cord-310847-63gh2tg4	346	48	lifestyles	lifestyle	NNS
cord-310847-63gh2tg4	346	49	(	(	-LRB-
cord-310847-63gh2tg4	346	50	mesophily	mesophily	NNP
cord-310847-63gh2tg4	346	51	,	,	,
cord-310847-63gh2tg4	346	52	thermophily	thermophily	NNP
cord-310847-63gh2tg4	346	53	or	or	CC
cord-310847-63gh2tg4	346	54	hyperthermophily	hyperthermophily	NNP
cord-310847-63gh2tg4	346	55	)	)	-RRB-
cord-310847-63gh2tg4	346	56	.	.	.
cord-310847-63gh2tg4	347	1	132	132	CD
cord-310847-63gh2tg4	348	1	The	the	DT
cord-310847-63gh2tg4	348	2	most	most	RBS
cord-310847-63gh2tg4	348	3	specific	specific	JJ
cord-310847-63gh2tg4	348	4	amino	amino	NN
cord-310847-63gh2tg4	348	5	acid	acid	NN
cord-310847-63gh2tg4	348	6	compositional	compositional	JJ
cord-310847-63gh2tg4	348	7	biases	bias	NNS
cord-310847-63gh2tg4	348	8	that	that	WDT
cord-310847-63gh2tg4	348	9	represent	represent	VBP
cord-310847-63gh2tg4	348	10	specific	specific	JJ
cord-310847-63gh2tg4	348	11	signatures	signature	NNS
cord-310847-63gh2tg4	348	12	of	of	IN
cord-310847-63gh2tg4	348	13	thermophilic	thermophilic	JJ
cord-310847-63gh2tg4	348	14	and	and	CC
cord-310847-63gh2tg4	348	15	hyperthermophilic	hyperthermophilic	JJ
cord-310847-63gh2tg4	348	16	proteomes	proteome	NNS
cord-310847-63gh2tg4	348	17	are	be	VBP
cord-310847-63gh2tg4	348	18	a	a	DT
cord-310847-63gh2tg4	348	19	relative	relative	JJ
cord-310847-63gh2tg4	348	20	abundance	abundance	NN
cord-310847-63gh2tg4	348	21	in	in	IN
cord-310847-63gh2tg4	348	22	glutamic	glutamic	NN
cord-310847-63gh2tg4	348	23	acid	acid	NN
cord-310847-63gh2tg4	348	24	,	,	,
cord-310847-63gh2tg4	348	25	concomitantly	concomitantly	RB
cord-310847-63gh2tg4	348	26	with	with	IN
cord-310847-63gh2tg4	348	27	a	a	DT
cord-310847-63gh2tg4	348	28	depletion	depletion	NN
cord-310847-63gh2tg4	348	29	in	in	IN
cord-310847-63gh2tg4	348	30	glutamine	glutamine	NN
cord-310847-63gh2tg4	348	31	and	and	CC
cord-310847-63gh2tg4	348	32	a	a	DT
cord-310847-63gh2tg4	348	33	significant	significant	JJ
cord-310847-63gh2tg4	348	34	correlation	correlation	NN
cord-310847-63gh2tg4	348	35	between	between	IN
cord-310847-63gh2tg4	348	36	the	the	DT
cord-310847-63gh2tg4	348	37	relative	relative	JJ
cord-310847-63gh2tg4	348	38	abundance	abundance	NN
cord-310847-63gh2tg4	348	39	in	in	IN
cord-310847-63gh2tg4	348	40	glutamic	glutamic	NN
cord-310847-63gh2tg4	348	41	acid	acid	NN
cord-310847-63gh2tg4	348	42	(	(	-LRB-
cord-310847-63gh2tg4	348	43	negative	negative	JJ
cord-310847-63gh2tg4	348	44	charge	charge	NN
cord-310847-63gh2tg4	348	45	)	)	-RRB-
cord-310847-63gh2tg4	348	46	and	and	CC
cord-310847-63gh2tg4	348	47	the	the	DT
cord-310847-63gh2tg4	348	48	increase	increase	NN
cord-310847-63gh2tg4	348	49	in	in	IN
cord-310847-63gh2tg4	348	50	the	the	DT
cord-310847-63gh2tg4	348	51	lumped	lumped	JJ
cord-310847-63gh2tg4	348	52	"	"	``
cord-310847-63gh2tg4	348	53	pool	pool	NN
cord-310847-63gh2tg4	348	54	"	"	''
cord-310847-63gh2tg4	348	55	lysine	lysine	NN
cord-310847-63gh2tg4	348	56	+	+	CC
cord-310847-63gh2tg4	348	57	arginine	arginine	NN
cord-310847-63gh2tg4	348	58	(	(	-LRB-
cord-310847-63gh2tg4	348	59	positive	positive	JJ
cord-310847-63gh2tg4	348	60	charges	charge	NNS
cord-310847-63gh2tg4	348	61	)	)	-RRB-
cord-310847-63gh2tg4	348	62	.	.	.
cord-310847-63gh2tg4	349	1	Being	be	VBG
cord-310847-63gh2tg4	349	2	absent	absent	JJ
cord-310847-63gh2tg4	349	3	in	in	IN
cord-310847-63gh2tg4	349	4	mesophiles	mesophile	NNS
cord-310847-63gh2tg4	349	5	,	,	,
cord-310847-63gh2tg4	349	6	these	these	DT
cord-310847-63gh2tg4	349	7	correlations	correlation	NNS
cord-310847-63gh2tg4	349	8	could	could	MD
cord-310847-63gh2tg4	349	9	represent	represent	VB
cord-310847-63gh2tg4	349	10	a	a	DT
cord-310847-63gh2tg4	349	11	physico	physico	NN
cord-310847-63gh2tg4	349	12	-	-	HYPH
cord-310847-63gh2tg4	349	13	chemical	chemical	NN
cord-310847-63gh2tg4	349	14	basis	basis	NN
cord-310847-63gh2tg4	349	15	of	of	IN
cord-310847-63gh2tg4	349	16	protein	protein	NN
cord-310847-63gh2tg4	349	17	thermostability	thermostability	NN
cord-310847-63gh2tg4	349	18	.	.	.
cord-310847-63gh2tg4	350	1	Curiously	curiously	RB
cord-310847-63gh2tg4	350	2	,	,	,
cord-310847-63gh2tg4	350	3	the	the	DT
cord-310847-63gh2tg4	350	4	distribution	distribution	NN
cord-310847-63gh2tg4	350	5	of	of	IN
cord-310847-63gh2tg4	350	6	the	the	DT
cord-310847-63gh2tg4	350	7	remaining	remain	VBG
cord-310847-63gh2tg4	350	8	charged	charge	VBN
cord-310847-63gh2tg4	350	9	amino	amino	NN
cord-310847-63gh2tg4	350	10	acid	acid	NN
cord-310847-63gh2tg4	350	11	,	,	,
cord-310847-63gh2tg4	350	12	i.e.	i.e.	FW
cord-310847-63gh2tg4	350	13	,	,	,
cord-310847-63gh2tg4	350	14	aspartic	aspartic	JJ
cord-310847-63gh2tg4	350	15	acid	acid	NN
cord-310847-63gh2tg4	350	16	,	,	,
cord-310847-63gh2tg4	350	17	appears	appear	VBZ
cord-310847-63gh2tg4	350	18	to	to	TO
cord-310847-63gh2tg4	350	19	be	be	VB
cord-310847-63gh2tg4	350	20	quite	quite	RB
cord-310847-63gh2tg4	350	21	homogeneous	homogeneous	JJ
cord-310847-63gh2tg4	350	22	throughout	throughout	IN
cord-310847-63gh2tg4	350	23	all	all	PDT
cord-310847-63gh2tg4	350	24	the	the	DT
cord-310847-63gh2tg4	350	25	species	specie	NNS
cord-310847-63gh2tg4	350	26	suggesting	suggest	VBG
cord-310847-63gh2tg4	350	27	that	that	IN
cord-310847-63gh2tg4	350	28	this	this	DT
cord-310847-63gh2tg4	350	29	residue	residue	NN
cord-310847-63gh2tg4	350	30	does	do	VBZ
cord-310847-63gh2tg4	350	31	not	not	RB
cord-310847-63gh2tg4	350	32	participate	participate	VB
cord-310847-63gh2tg4	350	33	significantly	significantly	RB
cord-310847-63gh2tg4	350	34	in	in	IN
cord-310847-63gh2tg4	350	35	the	the	DT
cord-310847-63gh2tg4	350	36	aforementioned	aforementioned	JJ
cord-310847-63gh2tg4	350	37	compensatory	compensatory	JJ
cord-310847-63gh2tg4	350	38	negative	negative	JJ
cord-310847-63gh2tg4	350	39	/	/	SYM
cord-310847-63gh2tg4	350	40	positive	positive	JJ
cord-310847-63gh2tg4	350	41	(	(	-LRB-
cord-310847-63gh2tg4	350	42	charged	charge	VBN
cord-310847-63gh2tg4	350	43	)	)	-RRB-
cord-310847-63gh2tg4	350	44	correlation	correlation	NN
cord-310847-63gh2tg4	350	45	in	in	IN
cord-310847-63gh2tg4	350	46	thermophiles	thermophile	NNS
cord-310847-63gh2tg4	350	47	and	and	CC
cord-310847-63gh2tg4	350	48	hyperthermophiles	hyperthermophile	NNS
cord-310847-63gh2tg4	350	49	.	.	.
cord-310847-63gh2tg4	351	1	132	132	CD
cord-310847-63gh2tg4	352	1	On	on	IN
cord-310847-63gh2tg4	352	2	average	average	JJ
cord-310847-63gh2tg4	352	3	,	,	,
cord-310847-63gh2tg4	352	4	thermophilic	thermophilic	JJ
cord-310847-63gh2tg4	352	5	and	and	CC
cord-310847-63gh2tg4	352	6	hyperthermophilic	hyperthermophilic	JJ
cord-310847-63gh2tg4	352	7	proteomes	proteome	NNS
cord-310847-63gh2tg4	352	8	were	be	VBD
cord-310847-63gh2tg4	352	9	shown	show	VBN
cord-310847-63gh2tg4	352	10	to	to	TO
cord-310847-63gh2tg4	352	11	contain	contain	VB
cord-310847-63gh2tg4	352	12	1.9	1.9	CD
cord-310847-63gh2tg4	352	13	%	%	NN
cord-310847-63gh2tg4	352	14	,	,	,
cord-310847-63gh2tg4	352	15	7.8	7.8	CD
cord-310847-63gh2tg4	352	16	%	%	NN
cord-310847-63gh2tg4	352	17	,	,	,
cord-310847-63gh2tg4	352	18	4.8	4.8	CD
cord-310847-63gh2tg4	352	19	%	%	NN
cord-310847-63gh2tg4	352	20	and	and	CC
cord-310847-63gh2tg4	352	21	12.6	12.6	CD
cord-310847-63gh2tg4	352	22	%	%	NN
cord-310847-63gh2tg4	352	23	of	of	IN
cord-310847-63gh2tg4	352	24	glutamine	glutamine	NN
cord-310847-63gh2tg4	352	25	,	,	,
cord-310847-63gh2tg4	352	26	glutamic	glutamic	NN
cord-310847-63gh2tg4	352	27	acid	acid	NN
cord-310847-63gh2tg4	352	28	,	,	,
cord-310847-63gh2tg4	352	29	aspartic	aspartic	JJ
cord-310847-63gh2tg4	352	30	acid	acid	NN
cord-310847-63gh2tg4	352	31	and	and	CC
cord-310847-63gh2tg4	352	32	lysine	lysine	NN
cord-310847-63gh2tg4	352	33	+	+	CC
cord-310847-63gh2tg4	352	34	arginine	arginine	NN
cord-310847-63gh2tg4	352	35	residues	residue	NNS
cord-310847-63gh2tg4	352	36	,	,	,
cord-310847-63gh2tg4	352	37	respectively	respectively	RB
cord-310847-63gh2tg4	352	38	.	.	.
cord-310847-63gh2tg4	353	1	Importantly	importantly	RB
cord-310847-63gh2tg4	353	2	,	,	,
cord-310847-63gh2tg4	353	3	some	some	DT
cord-310847-63gh2tg4	353	4	of	of	IN
cord-310847-63gh2tg4	353	5	these	these	DT
cord-310847-63gh2tg4	353	6	numbers	number	NNS
cord-310847-63gh2tg4	353	7	are	be	VBP
cord-310847-63gh2tg4	353	8	rather	rather	RB
cord-310847-63gh2tg4	353	9	different	different	JJ
cord-310847-63gh2tg4	353	10	from	from	IN
cord-310847-63gh2tg4	353	11	those	those	DT
cord-310847-63gh2tg4	353	12	found	find	VBN
cord-310847-63gh2tg4	353	13	in	in	IN
cord-310847-63gh2tg4	353	14	IDPs	IDPs	NNP
cord-310847-63gh2tg4	353	15	/	/	SYM
cord-310847-63gh2tg4	353	16	IDPRs	IDPRs	NNP
cord-310847-63gh2tg4	353	17	,	,	,
cord-310847-63gh2tg4	353	18	as	as	IN
cord-310847-63gh2tg4	353	19	shown	show	VBN
cord-310847-63gh2tg4	353	20	in	in	IN
cord-310847-63gh2tg4	353	21	Table	Table	NNP
cord-310847-63gh2tg4	353	22	1	1	CD
cord-310847-63gh2tg4	353	23	.	.	.
cord-310847-63gh2tg4	354	1	α	α	NNP
cord-310847-63gh2tg4	354	2	-	-	HYPH
cord-310847-63gh2tg4	354	3	lactabumin	lactabumin	NNP
cord-310847-63gh2tg4	354	4	was	be	VBD
cord-310847-63gh2tg4	354	5	shown	show	VBN
cord-310847-63gh2tg4	354	6	to	to	TO
cord-310847-63gh2tg4	354	7	possess	possess	VB
cord-310847-63gh2tg4	354	8	significantly	significantly	RB
cord-310847-63gh2tg4	354	9	different	different	JJ
cord-310847-63gh2tg4	354	10	thermal	thermal	JJ
cord-310847-63gh2tg4	354	11	and	and	CC
cord-310847-63gh2tg4	354	12	structural	structural	JJ
cord-310847-63gh2tg4	354	13	stability	stability	NN
cord-310847-63gh2tg4	354	14	in	in	IN
cord-310847-63gh2tg4	354	15	its	-PRON-	PRP$
cord-310847-63gh2tg4	354	16	calcium	calcium	NN
cord-310847-63gh2tg4	354	17	-	-	HYPH
cord-310847-63gh2tg4	354	18	bound	bind	VBN
cord-310847-63gh2tg4	354	19	and	and	CC
cord-310847-63gh2tg4	354	20	calciumfree	calciumfree	NNP
cord-310847-63gh2tg4	354	21	apo	apo	NNP
cord-310847-63gh2tg4	354	22	-	-	HYPH
cord-310847-63gh2tg4	354	23	forms	form	NNS
cord-310847-63gh2tg4	354	24	,	,	,
cord-310847-63gh2tg4	354	25	122	122	CD
cord-310847-63gh2tg4	354	26	with	with	IN
cord-310847-63gh2tg4	354	27	the	the	DT
cord-310847-63gh2tg4	354	28	apo	apo	NNP
cord-310847-63gh2tg4	354	29	-	-	HYPH
cord-310847-63gh2tg4	354	30	protein	protein	NNP
cord-310847-63gh2tg4	354	31	possessing	possess	VBG
cord-310847-63gh2tg4	354	32	molten	molten	JJ
cord-310847-63gh2tg4	354	33	globule	globule	NN
cord-310847-63gh2tg4	354	34	-	-	HYPH
cord-310847-63gh2tg4	354	35	like	like	JJ
cord-310847-63gh2tg4	354	36	properties	property	NNS
cord-310847-63gh2tg4	354	37	at	at	IN
cord-310847-63gh2tg4	354	38	slightly	slightly	RB
cord-310847-63gh2tg4	354	39	elevated	elevated	JJ
cord-310847-63gh2tg4	354	40	temperatures	temperature	NNS
cord-310847-63gh2tg4	354	41	.	.	.
cord-310847-63gh2tg4	355	1	123	123	CD
cord-310847-63gh2tg4	355	2	,	,	,
cord-310847-63gh2tg4	355	3	124	124	CD
cord-310847-63gh2tg4	356	1	This	this	DT
cord-310847-63gh2tg4	356	2	strong	strong	JJ
cord-310847-63gh2tg4	356	3	dependence	dependence	NN
cord-310847-63gh2tg4	356	4	of	of	IN
cord-310847-63gh2tg4	356	5	the	the	DT
cord-310847-63gh2tg4	356	6	α	α	XX
cord-310847-63gh2tg4	356	7	-	-	HYPH
cord-310847-63gh2tg4	356	8	lactabumin	lactabumin	NN
cord-310847-63gh2tg4	356	9	structural	structural	JJ
cord-310847-63gh2tg4	356	10	properties	property	NNS
cord-310847-63gh2tg4	356	11	on	on	IN
cord-310847-63gh2tg4	356	12	metal	metal	NN
cord-310847-63gh2tg4	356	13	-	-	HYPH
cord-310847-63gh2tg4	356	14	binding	binding	NN
cord-310847-63gh2tg4	356	15	is	be	VBZ
cord-310847-63gh2tg4	356	16	determined	determine	VBN
cord-310847-63gh2tg4	356	17	by	by	IN
cord-310847-63gh2tg4	356	18	the	the	DT
cord-310847-63gh2tg4	356	19	simple	simple	JJ
cord-310847-63gh2tg4	356	20	fact	fact	NN
cord-310847-63gh2tg4	356	21	that	that	IN
cord-310847-63gh2tg4	356	22	in	in	IN
cord-310847-63gh2tg4	356	23	the	the	DT
cord-310847-63gh2tg4	356	24	apo	apo	NNP
cord-310847-63gh2tg4	356	25	-	-	HYPH
cord-310847-63gh2tg4	356	26	form	form	NN
cord-310847-63gh2tg4	356	27	,	,	,
cord-310847-63gh2tg4	356	28	many	many	JJ
cord-310847-63gh2tg4	356	29	acidic	acidic	JJ
cord-310847-63gh2tg4	356	30	side	side	NN
cord-310847-63gh2tg4	356	31	chains	chain	NNS
cord-310847-63gh2tg4	356	32	have	have	VBP
cord-310847-63gh2tg4	356	33	unfavorable	unfavorable	JJ
cord-310847-63gh2tg4	356	34	chargecharge	chargecharge	NN
cord-310847-63gh2tg4	356	35	interactions	interaction	NNS
cord-310847-63gh2tg4	356	36	,	,	,
cord-310847-63gh2tg4	356	37	with	with	IN
cord-310847-63gh2tg4	356	38	11	11	CD
cord-310847-63gh2tg4	356	39	residues	residue	NNS
cord-310847-63gh2tg4	356	40	(	(	-LRB-
cord-310847-63gh2tg4	356	41	Glu1	Glu1	NNP
cord-310847-63gh2tg4	356	42	,	,	,
cord-310847-63gh2tg4	356	43	Glu7	Glu7	NNP
cord-310847-63gh2tg4	356	44	,	,	,
cord-310847-63gh2tg4	356	45	Glu11	Glu11	NNP
cord-310847-63gh2tg4	356	46	,	,	,
cord-310847-63gh2tg4	356	47	Asp63	Asp63	NNP
cord-310847-63gh2tg4	356	48	,	,	,
cord-310847-63gh2tg4	356	49	Asp64	Asp64	NNP
cord-310847-63gh2tg4	356	50	,	,	,
cord-310847-63gh2tg4	356	51	Asp78	Asp78	NNP
cord-310847-63gh2tg4	356	52	,	,	,
cord-310847-63gh2tg4	356	53	Asp82	Asp82	NNP
cord-310847-63gh2tg4	356	54	,	,	,
cord-310847-63gh2tg4	356	55	Asp83	Asp83	NNP
cord-310847-63gh2tg4	356	56	,	,	,
cord-310847-63gh2tg4	356	57	Asp84	Asp84	NNP
cord-310847-63gh2tg4	356	58	,	,	,
cord-310847-63gh2tg4	356	59	Asp87	Asp87	NNP
cord-310847-63gh2tg4	356	60	and	and	CC
cord-310847-63gh2tg4	356	61	Asp88	Asp88	NNP
cord-310847-63gh2tg4	356	62	)	)	-RRB-
cord-310847-63gh2tg4	356	63	possessing	possess	VBG
cord-310847-63gh2tg4	356	64	significantly	significantly	RB
cord-310847-63gh2tg4	356	65	unfavorable	unfavorable	JJ
cord-310847-63gh2tg4	356	66	charge	charge	NN
cord-310847-63gh2tg4	356	67	-	-	HYPH
cord-310847-63gh2tg4	356	68	charge	charge	NN
cord-310847-63gh2tg4	356	69	repultion	repultion	NN
cord-310847-63gh2tg4	356	70	.	.	.
cord-310847-63gh2tg4	357	1	125	125	CD
cord-310847-63gh2tg4	358	1	Although	although	IN
cord-310847-63gh2tg4	358	2	calcium	calcium	NN
cord-310847-63gh2tg4	358	3	binding	binding	NN
cord-310847-63gh2tg4	358	4	has	have	VBZ
cord-310847-63gh2tg4	358	5	the	the	DT
cord-310847-63gh2tg4	358	6	most	most	RBS
cord-310847-63gh2tg4	358	7	pronounced	pronounce	VBN
cord-310847-63gh2tg4	358	8	effect	effect	NN
cord-310847-63gh2tg4	358	9	on	on	IN
cord-310847-63gh2tg4	358	10	residues	residue	NNS
cord-310847-63gh2tg4	358	11	directly	directly	RB
cord-310847-63gh2tg4	358	12	involved	involve	VBN
cord-310847-63gh2tg4	358	13	in	in	IN
cord-310847-63gh2tg4	358	14	cation	cation	NN
cord-310847-63gh2tg4	358	15	coordination	coordination	NN
cord-310847-63gh2tg4	358	16	(	(	-LRB-
cord-310847-63gh2tg4	358	17	Asp82	Asp82	NNP
cord-310847-63gh2tg4	358	18	,	,	,
cord-310847-63gh2tg4	358	19	Asp87	Asp87	NNP
cord-310847-63gh2tg4	358	20	and	and	CC
cord-310847-63gh2tg4	358	21	Asp88	Asp88	NNP
cord-310847-63gh2tg4	358	22	)	)	-RRB-
cord-310847-63gh2tg4	358	23	and	and	CC
cord-310847-63gh2tg4	358	24	strongly	strongly	RB
cord-310847-63gh2tg4	358	25	affects	affect	VBZ
cord-310847-63gh2tg4	358	26	the	the	DT
cord-310847-63gh2tg4	358	27	other	other	JJ
cord-310847-63gh2tg4	358	28	two	two	CD
cord-310847-63gh2tg4	358	29	residues	residue	NNS
cord-310847-63gh2tg4	358	30	in	in	IN
cord-310847-63gh2tg4	358	31	the	the	DT
cord-310847-63gh2tg4	358	32	Ca	Ca	NNP
cord-310847-63gh2tg4	358	33	2	2	CD
cord-310847-63gh2tg4	358	34	+	+	SYM
cord-310847-63gh2tg4	358	35	-binding	-binding	NN
cord-310847-63gh2tg4	358	36	loop	loop	NN
cord-310847-63gh2tg4	358	37	,	,	,
cord-310847-63gh2tg4	358	38	Asp83	Asp83	NNP
cord-310847-63gh2tg4	358	39	and	and	CC
cord-310847-63gh2tg4	358	40	Asp84	Asp84	NNP
cord-310847-63gh2tg4	358	41	,	,	,
cord-310847-63gh2tg4	359	1	Ca	ca	NN
cord-310847-63gh2tg4	359	2	2	2	CD
cord-310847-63gh2tg4	359	3	+	+	CC
cord-310847-63gh2tg4	359	4	binding	binding	NN
cord-310847-63gh2tg4	359	5	has	have	VBZ
cord-310847-63gh2tg4	359	6	relatively	relatively	RB
cord-310847-63gh2tg4	359	7	minor	minor	JJ
cord-310847-63gh2tg4	359	8	effects	effect	NNS
cord-310847-63gh2tg4	359	9	on	on	IN
cord-310847-63gh2tg4	359	10	residues	residue	NNS
cord-310847-63gh2tg4	359	11	more	more	RBR
cord-310847-63gh2tg4	359	12	distant	distant	JJ
cord-310847-63gh2tg4	359	13	from	from	IN
cord-310847-63gh2tg4	359	14	the	the	DT
cord-310847-63gh2tg4	359	15	Ca	Ca	NNP
cord-310847-63gh2tg4	359	16	2	2	CD
cord-310847-63gh2tg4	359	17	+	+	SYM
cord-310847-63gh2tg4	359	18	-binding	-binding	NN
cord-310847-63gh2tg4	359	19	site	site	NN
cord-310847-63gh2tg4	359	20	(	(	-LRB-
cord-310847-63gh2tg4	359	21	Glu1	Glu1	NNP
cord-310847-63gh2tg4	359	22	,	,	,
cord-310847-63gh2tg4	359	23	Glu7	Glu7	NNP
cord-310847-63gh2tg4	359	24	,	,	,
cord-310847-63gh2tg4	359	25	Glu11	Glu11	NNP
cord-310847-63gh2tg4	359	26	,	,	,
cord-310847-63gh2tg4	359	27	Asp63	Asp63	NNP
cord-310847-63gh2tg4	359	28	and	and	CC
cord-310847-63gh2tg4	359	29	Asp64	Asp64	NNP
cord-310847-63gh2tg4	359	30	)	)	-RRB-
cord-310847-63gh2tg4	359	31	,	,	,
cord-310847-63gh2tg4	359	32	which	which	WDT
cord-310847-63gh2tg4	359	33	mostly	mostly	RB
cord-310847-63gh2tg4	359	34	preserve	preserve	VBP
cord-310847-63gh2tg4	359	35	unfavorable	unfavorable	JJ
cord-310847-63gh2tg4	359	36	electrostatic	electrostatic	JJ
cord-310847-63gh2tg4	359	37	interactions	interaction	NNS
cord-310847-63gh2tg4	359	38	seen	see	VBN
cord-310847-63gh2tg4	359	39	in	in	IN
cord-310847-63gh2tg4	359	40	the	the	DT
cord-310847-63gh2tg4	359	41	apo	apo	NNP
cord-310847-63gh2tg4	359	42	-	-	HYPH
cord-310847-63gh2tg4	359	43	form	form	NN
cord-310847-63gh2tg4	359	44	.	.	.
cord-310847-63gh2tg4	360	1	125	125	CD
cord-310847-63gh2tg4	361	1	It	-PRON-	PRP
cord-310847-63gh2tg4	361	2	was	be	VBD
cord-310847-63gh2tg4	361	3	also	also	RB
cord-310847-63gh2tg4	361	4	shown	show	VBN
cord-310847-63gh2tg4	361	5	that	that	IN
cord-310847-63gh2tg4	361	6	the	the	DT
cord-310847-63gh2tg4	361	7	mutation	mutation	NN
cord-310847-63gh2tg4	361	8	-	-	HYPH
cord-310847-63gh2tg4	361	9	induced	induce	VBN
cord-310847-63gh2tg4	361	10	neutralization	neutralization	NN
cord-310847-63gh2tg4	361	11	of	of	IN
cord-310847-63gh2tg4	361	12	unfavorable	unfavorable	JJ
cord-310847-63gh2tg4	361	13	charge	charge	NN
cord-310847-63gh2tg4	361	14	-	-	HYPH
cord-310847-63gh2tg4	361	15	charge	charge	NN
cord-310847-63gh2tg4	361	16	interactions	interaction	NNS
cord-310847-63gh2tg4	361	17	in	in	IN
cord-310847-63gh2tg4	361	18	the	the	DT
cord-310847-63gh2tg4	361	19	N	n	CD
cord-310847-63gh2tg4	361	20	-	-	HYPH
cord-310847-63gh2tg4	361	21	terminus	terminus	NN
cord-310847-63gh2tg4	361	22	(	(	-LRB-
cord-310847-63gh2tg4	361	23	residues	residue	NNS
cord-310847-63gh2tg4	361	24	1	1	CD
cord-310847-63gh2tg4	361	25	-	-	SYM
cord-310847-63gh2tg4	361	26	11	11	CD
cord-310847-63gh2tg4	361	27	of	of	IN
cord-310847-63gh2tg4	361	28	which	which	WDT
cord-310847-63gh2tg4	361	29	are	be	VBP
cord-310847-63gh2tg4	361	30	characterized	characterize	VBN
cord-310847-63gh2tg4	361	31	by	by	IN
cord-310847-63gh2tg4	361	32	a	a	DT
cord-310847-63gh2tg4	361	33	high	high	JJ
cord-310847-63gh2tg4	361	34	proportion	proportion	NN
cord-310847-63gh2tg4	361	35	of	of	IN
cord-310847-63gh2tg4	361	36	negatively	negatively	RB
cord-310847-63gh2tg4	361	37	charged	charge	VBN
cord-310847-63gh2tg4	361	38	residues	residue	NNS
cord-310847-63gh2tg4	361	39	that	that	WDT
cord-310847-63gh2tg4	361	40	cluster	cluster	NN
cord-310847-63gh2tg4	361	41	on	on	IN
cord-310847-63gh2tg4	361	42	the	the	DT
cord-310847-63gh2tg4	361	43	surface	surface	NN
cord-310847-63gh2tg4	361	44	of	of	IN
cord-310847-63gh2tg4	361	45	the	the	DT
cord-310847-63gh2tg4	361	46	native	native	JJ
cord-310847-63gh2tg4	361	47	protein	protein	NN
cord-310847-63gh2tg4	361	48	)	)	-RRB-
cord-310847-63gh2tg4	361	49	results	result	NNS
cord-310847-63gh2tg4	361	50	in	in	IN
cord-310847-63gh2tg4	361	51	stabilization	stabilization	NN
cord-310847-63gh2tg4	361	52	of	of	IN
cord-310847-63gh2tg4	361	53	both	both	CC
cord-310847-63gh2tg4	361	54	the	the	DT
cord-310847-63gh2tg4	361	55	apo	apo	NNP
cord-310847-63gh2tg4	361	56	-	-	:
cord-310847-63gh2tg4	361	57	and	and	CC
cord-310847-63gh2tg4	361	58	Ca	Ca	NNP
cord-310847-63gh2tg4	361	59	2+bound	2+bound	CD
cord-310847-63gh2tg4	361	60	protein	protein	NN
cord-310847-63gh2tg4	361	61	.	.	.
cord-310847-63gh2tg4	362	1	125	125	CD
cord-310847-63gh2tg4	363	1	Unexpectedly	unexpectedly	RB
cord-310847-63gh2tg4	363	2	,	,	,
cord-310847-63gh2tg4	363	3	the	the	DT
cord-310847-63gh2tg4	363	4	ΔGlu1	δglu1	CD
cord-310847-63gh2tg4	363	5	mutant	mutant	NN
cord-310847-63gh2tg4	363	6	,	,	,
cord-310847-63gh2tg4	363	7	where	where	WRB
cord-310847-63gh2tg4	363	8	the	the	DT
cord-310847-63gh2tg4	363	9	Glu1	Glu1	NNP
cord-310847-63gh2tg4	363	10	residue	residue	NN
cord-310847-63gh2tg4	363	11	was	be	VBD
cord-310847-63gh2tg4	363	12	removed	remove	VBN
cord-310847-63gh2tg4	363	13	,	,	,
cord-310847-63gh2tg4	363	14	leaving	leave	VBG
cord-310847-63gh2tg4	363	15	an	an	DT
cord-310847-63gh2tg4	363	16	N	n	CD
cord-310847-63gh2tg4	363	17	-	-	HYPH
cord-310847-63gh2tg4	363	18	terminal	terminal	NN
cord-310847-63gh2tg4	363	19	methionine	methionine	NN
cord-310847-63gh2tg4	363	20	in	in	IN
cord-310847-63gh2tg4	363	21	its	-PRON-	PRP$
cord-310847-63gh2tg4	363	22	place	place	NN
cord-310847-63gh2tg4	363	23	,	,	,
cord-310847-63gh2tg4	363	24	possessed	possess	VBD
cord-310847-63gh2tg4	363	25	almost	almost	RB
cord-310847-63gh2tg4	363	26	one	one	CD
cord-310847-63gh2tg4	363	27	order	order	NN
cord-310847-63gh2tg4	363	28	of	of	IN
cord-310847-63gh2tg4	363	29	magnitude	magnitude	NN
cord-310847-63gh2tg4	363	30	higher	high	JJR
cord-310847-63gh2tg4	363	31	affinity	affinity	NN
cord-310847-63gh2tg4	363	32	for	for	IN
cord-310847-63gh2tg4	363	33	calcium	calcium	NN
cord-310847-63gh2tg4	363	34	and	and	CC
cord-310847-63gh2tg4	363	35	higher	high	JJR
cord-310847-63gh2tg4	363	36	thermostability	thermostability	NN
cord-310847-63gh2tg4	363	37	(	(	-LRB-
cord-310847-63gh2tg4	363	38	both	both	DT
cord-310847-63gh2tg4	363	39	in	in	IN
cord-310847-63gh2tg4	363	40	the	the	DT
cord-310847-63gh2tg4	363	41	absence	absence	NN
cord-310847-63gh2tg4	363	42	and	and	CC
cord-310847-63gh2tg4	363	43	presence	presence	NN
cord-310847-63gh2tg4	363	44	of	of	IN
cord-310847-63gh2tg4	363	45	calcium	calcium	NN
cord-310847-63gh2tg4	363	46	)	)	-RRB-
cord-310847-63gh2tg4	363	47	than	than	IN
cord-310847-63gh2tg4	363	48	the	the	DT
cord-310847-63gh2tg4	363	49	native	native	JJ
cord-310847-63gh2tg4	363	50	protein	protein	NN
cord-310847-63gh2tg4	363	51	isolated	isolate	VBN
cord-310847-63gh2tg4	363	52	from	from	IN
cord-310847-63gh2tg4	363	53	milk	milk	NN
cord-310847-63gh2tg4	363	54	.	.	.
cord-310847-63gh2tg4	364	1	121	121	CD
cord-310847-63gh2tg4	365	1	This	this	DT
cord-310847-63gh2tg4	365	2	unique	unique	JJ
cord-310847-63gh2tg4	365	3	tuning	tuning	NN
cord-310847-63gh2tg4	365	4	of	of	IN
cord-310847-63gh2tg4	365	5	the	the	DT
cord-310847-63gh2tg4	365	6	α	α	NNP
cord-310847-63gh2tg4	365	7	-	-	HYPH
cord-310847-63gh2tg4	365	8	lactabumin	lactabumin	NNP
cord-310847-63gh2tg4	365	9	structure	structure	NN
cord-310847-63gh2tg4	365	10	and	and	CC
cord-310847-63gh2tg4	365	11	calcium	calcium	NN
cord-310847-63gh2tg4	365	12	binding	binding	NN
cord-310847-63gh2tg4	365	13	suggested	suggest	VBD
cord-310847-63gh2tg4	365	14	that	that	IN
cord-310847-63gh2tg4	365	15	the	the	DT
cord-310847-63gh2tg4	365	16	N	n	CD
cord-310847-63gh2tg4	365	17	-	-	HYPH
cord-310847-63gh2tg4	365	18	terminal	terminal	NN
cord-310847-63gh2tg4	365	19	region	region	NN
cord-310847-63gh2tg4	365	20	of	of	IN
cord-310847-63gh2tg4	365	21	this	this	DT
cord-310847-63gh2tg4	365	22	protein	protein	NN
cord-310847-63gh2tg4	365	23	might	may	MD
cord-310847-63gh2tg4	365	24	have	have	VB
cord-310847-63gh2tg4	365	25	a	a	DT
cord-310847-63gh2tg4	365	26	direct	direct	JJ
cord-310847-63gh2tg4	365	27	effect	effect	NN
cord-310847-63gh2tg4	365	28	on	on	IN
cord-310847-63gh2tg4	365	29	the	the	DT
cord-310847-63gh2tg4	365	30	calcium	calcium	NN
cord-310847-63gh2tg4	365	31	-	-	HYPH
cord-310847-63gh2tg4	365	32	binding	bind	VBG
cord-310847-63gh2tg4	365	33	loop	loop	NN
cord-310847-63gh2tg4	365	34	(	(	-LRB-
cord-310847-63gh2tg4	365	35	and	and	CC
cord-310847-63gh2tg4	365	36	perhaps	perhaps	RB
cord-310847-63gh2tg4	365	37	other	other	JJ
cord-310847-63gh2tg4	365	38	regions	region	NNS
cord-310847-63gh2tg4	365	39	of	of	IN
cord-310847-63gh2tg4	365	40	the	the	DT
cord-310847-63gh2tg4	365	41	structure	structure	NN
cord-310847-63gh2tg4	365	42	)	)	-RRB-
cord-310847-63gh2tg4	365	43	.	.	.
cord-310847-63gh2tg4	366	1	121	121	CD
cord-310847-63gh2tg4	367	1	The	the	DT
cord-310847-63gh2tg4	367	2	side	side	NN
cord-310847-63gh2tg4	367	3	chains	chain	NNS
cord-310847-63gh2tg4	367	4	of	of	IN
cord-310847-63gh2tg4	367	5	glutamic	glutamic	NN
cord-310847-63gh2tg4	367	6	acid	acid	NN
cord-310847-63gh2tg4	367	7	residues	residue	NNS
cord-310847-63gh2tg4	367	8	are	be	VBP
cord-310847-63gh2tg4	367	9	subjected	subject	VBN
cord-310847-63gh2tg4	367	10	to	to	IN
cord-310847-63gh2tg4	367	11	several	several	JJ
cord-310847-63gh2tg4	367	12	PTMs	ptm	NNS
cord-310847-63gh2tg4	367	13	.	.	.
cord-310847-63gh2tg4	368	1	Some	some	DT
cord-310847-63gh2tg4	368	2	cytoplasmic	cytoplasmic	JJ
cord-310847-63gh2tg4	368	3	and	and	CC
cord-310847-63gh2tg4	368	4	nuclear	nuclear	JJ
cord-310847-63gh2tg4	368	5	proteins	protein	NNS
cord-310847-63gh2tg4	368	6	are	be	VBP
cord-310847-63gh2tg4	368	7	known	know	VBN
cord-310847-63gh2tg4	368	8	to	to	TO
cord-310847-63gh2tg4	368	9	be	be	VB
cord-310847-63gh2tg4	368	10	methylated	methylate	VBN
cord-310847-63gh2tg4	368	11	,	,	,
cord-310847-63gh2tg4	368	12	i.e.	i.e.	FW
cord-310847-63gh2tg4	368	13	,	,	,
cord-310847-63gh2tg4	368	14	enzymatically	enzymatically	RB
cord-310847-63gh2tg4	368	15	modified	modify	VBN
cord-310847-63gh2tg4	368	16	by	by	IN
cord-310847-63gh2tg4	368	17	the	the	DT
cord-310847-63gh2tg4	368	18	addition	addition	NN
cord-310847-63gh2tg4	368	19	of	of	IN
cord-310847-63gh2tg4	368	20	methyl	methyl	NN
cord-310847-63gh2tg4	368	21	groups	group	NNS
cord-310847-63gh2tg4	368	22	from	from	IN
cord-310847-63gh2tg4	368	23	S	S	NNP
cord-310847-63gh2tg4	368	24	-	-	HYPH
cord-310847-63gh2tg4	368	25	adenosylmethionine	adenosylmethionine	NNP
cord-310847-63gh2tg4	368	26	.	.	.
cord-310847-63gh2tg4	369	1	Methylation	methylation	NN
cord-310847-63gh2tg4	369	2	reactions	reaction	NNS
cord-310847-63gh2tg4	369	3	typically	typically	RB
cord-310847-63gh2tg4	369	4	occur	occur	VBP
cord-310847-63gh2tg4	369	5	on	on	IN
cord-310847-63gh2tg4	369	6	carboxyl	carboxyl	NN
cord-310847-63gh2tg4	369	7	groups	group	NNS
cord-310847-63gh2tg4	369	8	(	(	-LRB-
cord-310847-63gh2tg4	369	9	such	such	JJ
cord-310847-63gh2tg4	369	10	as	as	IN
cord-310847-63gh2tg4	369	11	the	the	DT
cord-310847-63gh2tg4	369	12	side	side	NN
cord-310847-63gh2tg4	369	13	chain	chain	NN
cord-310847-63gh2tg4	369	14	of	of	IN
cord-310847-63gh2tg4	369	15	glutamic	glutamic	NN
cord-310847-63gh2tg4	369	16	acid	acid	NN
cord-310847-63gh2tg4	369	17	)	)	-RRB-
cord-310847-63gh2tg4	369	18	and	and	CC
cord-310847-63gh2tg4	369	19	modulate	modulate	VB
cord-310847-63gh2tg4	369	20	the	the	DT
cord-310847-63gh2tg4	369	21	activity	activity	NN
cord-310847-63gh2tg4	369	22	of	of	IN
cord-310847-63gh2tg4	369	23	the	the	DT
cord-310847-63gh2tg4	369	24	target	target	NN
cord-310847-63gh2tg4	369	25	protein	protein	NN
cord-310847-63gh2tg4	369	26	.	.	.
cord-310847-63gh2tg4	370	1	Glutamate	glutamate	NN
cord-310847-63gh2tg4	370	2	methyl	methyl	NN
cord-310847-63gh2tg4	370	3	ester	ester	NN
cord-310847-63gh2tg4	370	4	formation	formation	NN
cord-310847-63gh2tg4	370	5	plays	play	VBZ
cord-310847-63gh2tg4	370	6	a	a	DT
cord-310847-63gh2tg4	370	7	major	major	JJ
cord-310847-63gh2tg4	370	8	role	role	NN
cord-310847-63gh2tg4	370	9	in	in	IN
cord-310847-63gh2tg4	370	10	chemotactic	chemotactic	JJ
cord-310847-63gh2tg4	370	11	signal	signal	NN
cord-310847-63gh2tg4	370	12	transduction	transduction	NN
cord-310847-63gh2tg4	370	13	in	in	IN
cord-310847-63gh2tg4	370	14	prokaryotes	prokaryote	NNS
cord-310847-63gh2tg4	370	15	.	.	.
cord-310847-63gh2tg4	371	1	For	for	IN
cord-310847-63gh2tg4	371	2	example	example	NN
cord-310847-63gh2tg4	371	3	,	,	,
cord-310847-63gh2tg4	371	4	methyl	methyl	NN
cord-310847-63gh2tg4	371	5	-	-	HYPH
cord-310847-63gh2tg4	371	6	accepting	accept	VBG
cord-310847-63gh2tg4	371	7	chemotaxis	chemotaxis	NN
cord-310847-63gh2tg4	371	8	proteins	protein	NNS
cord-310847-63gh2tg4	371	9	are	be	VBP
cord-310847-63gh2tg4	371	10	a	a	DT
cord-310847-63gh2tg4	371	11	family	family	NN
cord-310847-63gh2tg4	371	12	of	of	IN
cord-310847-63gh2tg4	371	13	chemotactic	chemotactic	JJ
cord-310847-63gh2tg4	371	14	-	-	HYPH
cord-310847-63gh2tg4	371	15	signal	signal	NN
cord-310847-63gh2tg4	371	16	transducers	transducer	NNS
cord-310847-63gh2tg4	371	17	that	that	WDT
cord-310847-63gh2tg4	371	18	respond	respond	VBP
cord-310847-63gh2tg4	371	19	to	to	IN
cord-310847-63gh2tg4	371	20	changes	change	NNS
cord-310847-63gh2tg4	371	21	in	in	IN
cord-310847-63gh2tg4	371	22	the	the	DT
cord-310847-63gh2tg4	371	23	concentration	concentration	NN
cord-310847-63gh2tg4	371	24	of	of	IN
cord-310847-63gh2tg4	371	25	attractants	attractant	NNS
cord-310847-63gh2tg4	371	26	and	and	CC
cord-310847-63gh2tg4	371	27	repellents	repellent	NNS
cord-310847-63gh2tg4	371	28	in	in	IN
cord-310847-63gh2tg4	371	29	the	the	DT
cord-310847-63gh2tg4	371	30	environment	environment	NN
cord-310847-63gh2tg4	371	31	,	,	,
cord-310847-63gh2tg4	371	32	transduce	transduce	VB
cord-310847-63gh2tg4	371	33	a	a	DT
cord-310847-63gh2tg4	371	34	signal	signal	NN
cord-310847-63gh2tg4	371	35	from	from	IN
cord-310847-63gh2tg4	371	36	the	the	DT
cord-310847-63gh2tg4	371	37	outside	outside	NN
cord-310847-63gh2tg4	371	38	to	to	IN
cord-310847-63gh2tg4	371	39	the	the	DT
cord-310847-63gh2tg4	371	40	inside	inside	NN
cord-310847-63gh2tg4	371	41	of	of	IN
cord-310847-63gh2tg4	371	42	the	the	DT
cord-310847-63gh2tg4	371	43	cell	cell	NN
cord-310847-63gh2tg4	371	44	,	,	,
cord-310847-63gh2tg4	371	45	and	and	CC
cord-310847-63gh2tg4	371	46	facilitate	facilitate	VB
cord-310847-63gh2tg4	371	47	sensory	sensory	JJ
cord-310847-63gh2tg4	371	48	adaptation	adaptation	NN
cord-310847-63gh2tg4	371	49	through	through	IN
cord-310847-63gh2tg4	371	50	the	the	DT
cord-310847-63gh2tg4	371	51	variation	variation	NN
cord-310847-63gh2tg4	371	52	of	of	IN
cord-310847-63gh2tg4	371	53	the	the	DT
cord-310847-63gh2tg4	371	54	level	level	NN
cord-310847-63gh2tg4	371	55	of	of	IN
cord-310847-63gh2tg4	371	56	methylation	methylation	NN
cord-310847-63gh2tg4	371	57	.	.	.
cord-310847-63gh2tg4	372	1	126	126	CD
cord-310847-63gh2tg4	372	2	,	,	,
cord-310847-63gh2tg4	372	3	127	127	CD
cord-310847-63gh2tg4	373	1	In	in	IN
cord-310847-63gh2tg4	373	2	some	some	DT
cord-310847-63gh2tg4	373	3	proteins	protein	NNS
cord-310847-63gh2tg4	373	4	and	and	CC
cord-310847-63gh2tg4	373	5	peptides	peptide	NNS
cord-310847-63gh2tg4	373	6	,	,	,
cord-310847-63gh2tg4	373	7	glutamic	glutamic	NN
cord-310847-63gh2tg4	373	8	acids	acid	NNS
cord-310847-63gh2tg4	373	9	can	can	MD
cord-310847-63gh2tg4	373	10	be	be	VB
cord-310847-63gh2tg4	373	11	amidated	amidate	VBN
cord-310847-63gh2tg4	373	12	.	.	.
cord-310847-63gh2tg4	374	1	Also	also	RB
cord-310847-63gh2tg4	374	2	,	,	,
cord-310847-63gh2tg4	374	3	some	some	DT
cord-310847-63gh2tg4	374	4	glutamine	glutamine	NN
cord-310847-63gh2tg4	374	5	residues	residue	NNS
cord-310847-63gh2tg4	374	6	in	in	IN
cord-310847-63gh2tg4	374	7	proteins	protein	NNS
cord-310847-63gh2tg4	374	8	undergo	undergo	VBP
cord-310847-63gh2tg4	374	9	spontaneous	spontaneous	JJ
cord-310847-63gh2tg4	374	10	(	(	-LRB-
cord-310847-63gh2tg4	374	11	nonenzymatic	nonenzymatic	JJ
cord-310847-63gh2tg4	374	12	)	)	-RRB-
cord-310847-63gh2tg4	374	13	deamidation	deamidation	NN
cord-310847-63gh2tg4	374	14	to	to	IN
cord-310847-63gh2tg4	374	15	glutamate	glutamate	NN
cord-310847-63gh2tg4	374	16	with	with	IN
cord-310847-63gh2tg4	374	17	rates	rate	NNS
cord-310847-63gh2tg4	374	18	that	that	WDT
cord-310847-63gh2tg4	374	19	depend	depend	VBP
cord-310847-63gh2tg4	374	20	upon	upon	IN
cord-310847-63gh2tg4	374	21	the	the	DT
cord-310847-63gh2tg4	374	22	sequence	sequence	NN
cord-310847-63gh2tg4	374	23	and	and	CC
cord-310847-63gh2tg4	374	24	higher	high	JJR
cord-310847-63gh2tg4	374	25	-	-	HYPH
cord-310847-63gh2tg4	374	26	order	order	NN
cord-310847-63gh2tg4	374	27	structure	structure	NN
cord-310847-63gh2tg4	374	28	of	of	IN
cord-310847-63gh2tg4	374	29	the	the	DT
cord-310847-63gh2tg4	374	30	protein	protein	NN
cord-310847-63gh2tg4	374	31	.	.	.
cord-310847-63gh2tg4	375	1	Functional	functional	JJ
cord-310847-63gh2tg4	375	2	groups	group	NNS
cord-310847-63gh2tg4	375	3	within	within	IN
cord-310847-63gh2tg4	375	4	the	the	DT
cord-310847-63gh2tg4	375	5	protein	protein	NN
cord-310847-63gh2tg4	375	6	can	can	MD
cord-310847-63gh2tg4	375	7	catalyze	catalyze	VB
cord-310847-63gh2tg4	375	8	this	this	DT
cord-310847-63gh2tg4	375	9	reaction	reaction	NN
cord-310847-63gh2tg4	375	10	,	,	,
cord-310847-63gh2tg4	375	11	acting	act	VBG
cord-310847-63gh2tg4	375	12	as	as	IN
cord-310847-63gh2tg4	375	13	general	general	JJ
cord-310847-63gh2tg4	375	14	acids	acid	NNS
cord-310847-63gh2tg4	375	15	,	,	,
cord-310847-63gh2tg4	375	16	bases	basis	NNS
cord-310847-63gh2tg4	375	17	,	,	,
cord-310847-63gh2tg4	375	18	or	or	CC
cord-310847-63gh2tg4	375	19	stabilizers	stabilizer	NNS
cord-310847-63gh2tg4	375	20	of	of	IN
cord-310847-63gh2tg4	375	21	the	the	DT
cord-310847-63gh2tg4	375	22	transition	transition	NN
cord-310847-63gh2tg4	375	23	state	state	NN
cord-310847-63gh2tg4	375	24	.	.	.
cord-310847-63gh2tg4	376	1	128	128	CD
cord-310847-63gh2tg4	377	1	In	in	IN
cord-310847-63gh2tg4	377	2	rare	rare	JJ
cord-310847-63gh2tg4	377	3	cases	case	NNS
cord-310847-63gh2tg4	377	4	,	,	,
cord-310847-63gh2tg4	377	5	glutamate	glutamate	NN
cord-310847-63gh2tg4	377	6	residues	residue	NNS
cord-310847-63gh2tg4	377	7	can	can	MD
cord-310847-63gh2tg4	377	8	be	be	VB
cord-310847-63gh2tg4	377	9	modified	modify	VBN
cord-310847-63gh2tg4	377	10	by	by	IN
cord-310847-63gh2tg4	377	11	cyclization	cyclization	NN
cord-310847-63gh2tg4	377	12	via	via	IN
cord-310847-63gh2tg4	377	13	condensation	condensation	NN
cord-310847-63gh2tg4	377	14	of	of	IN
cord-310847-63gh2tg4	377	15	the	the	DT
cord-310847-63gh2tg4	377	16	α	α	NN
cord-310847-63gh2tg4	377	17	-	-	HYPH
cord-310847-63gh2tg4	377	18	amino	amino	NN
cord-310847-63gh2tg4	377	19	group	group	NN
cord-310847-63gh2tg4	377	20	with	with	IN
cord-310847-63gh2tg4	377	21	the	the	DT
cord-310847-63gh2tg4	377	22	side	side	NN
cord-310847-63gh2tg4	377	23	-	-	HYPH
cord-310847-63gh2tg4	377	24	chain	chain	NN
cord-310847-63gh2tg4	377	25	carboxyl	carboxyl	NN
cord-310847-63gh2tg4	377	26	neutral	neutral	JJ
cord-310847-63gh2tg4	377	27	pH	pH	NNP
cord-310847-63gh2tg4	377	28	was	be	VBD
cord-310847-63gh2tg4	377	29	shown	show	VBN
cord-310847-63gh2tg4	377	30	to	to	TO
cord-310847-63gh2tg4	377	31	be	be	VB
cord-310847-63gh2tg4	377	32	accompanied	accompany	VBN
cord-310847-63gh2tg4	377	33	by	by	IN
cord-310847-63gh2tg4	377	34	the	the	DT
cord-310847-63gh2tg4	377	35	instantaneous	instantaneous	JJ
cord-310847-63gh2tg4	377	36	formation	formation	NN
cord-310847-63gh2tg4	377	37	of	of	IN
cord-310847-63gh2tg4	377	38	a	a	DT
cord-310847-63gh2tg4	377	39	gel	gel	NN
cord-310847-63gh2tg4	377	40	-	-	HYPH
cord-310847-63gh2tg4	377	41	like	like	JJ
cord-310847-63gh2tg4	377	42	precipitate	precipitate	NN
cord-310847-63gh2tg4	377	43	with	with	IN
cord-310847-63gh2tg4	377	44	intermolecular	intermolecular	NNP
cord-310847-63gh2tg4	377	45	antiparallel	antiparallel	IN
cord-310847-63gh2tg4	377	46	β	β	NN
cord-310847-63gh2tg4	377	47	-	-	HYPH
cord-310847-63gh2tg4	377	48	structure	structure	NN
cord-310847-63gh2tg4	377	49	.	.	.
cord-310847-63gh2tg4	378	1	139	139	CD
cord-310847-63gh2tg4	379	1	In	in	IN
cord-310847-63gh2tg4	379	2	bacteria	bacteria	NNS
cord-310847-63gh2tg4	379	3	,	,	,
cord-310847-63gh2tg4	379	4	PGA	PGA	NNP
cord-310847-63gh2tg4	379	5	may	may	MD
cord-310847-63gh2tg4	379	6	be	be	VB
cord-310847-63gh2tg4	379	7	composed	compose	VBN
cord-310847-63gh2tg4	379	8	of	of	IN
cord-310847-63gh2tg4	379	9	only	only	RB
cord-310847-63gh2tg4	379	10	D-	d-	NN
cord-310847-63gh2tg4	379	11	,	,	,
cord-310847-63gh2tg4	379	12	only	only	RB
cord-310847-63gh2tg4	379	13	L	l	NN
cord-310847-63gh2tg4	379	14	-	-	,
cord-310847-63gh2tg4	379	15	or	or	CC
cord-310847-63gh2tg4	379	16	both	both	CC
cord-310847-63gh2tg4	379	17	D	D	NNP
cord-310847-63gh2tg4	379	18	-	-	:
cord-310847-63gh2tg4	379	19	and	and	CC
cord-310847-63gh2tg4	379	20	L	l	NN
cord-310847-63gh2tg4	379	21	-	-	HYPH
cord-310847-63gh2tg4	379	22	glutamate	glutamate	NN
cord-310847-63gh2tg4	379	23	enantiomers	enantiomer	NNS
cord-310847-63gh2tg4	379	24	,	,	,
cord-310847-63gh2tg4	379	25	and	and	CC
cord-310847-63gh2tg4	379	26	PGA	PGA	NNP
cord-310847-63gh2tg4	379	27	filaments	filament	NNS
cord-310847-63gh2tg4	379	28	may	may	MD
cord-310847-63gh2tg4	379	29	be	be	VB
cord-310847-63gh2tg4	379	30	poly	poly	NNP
cord-310847-63gh2tg4	379	31	-	-	HYPH
cord-310847-63gh2tg4	379	32	γ	γ	NNP
cord-310847-63gh2tg4	379	33	-	-	HYPH
cord-310847-63gh2tg4	379	34	L	l	NN
cord-310847-63gh2tg4	379	35	-	-	HYPH
cord-310847-63gh2tg4	379	36	glutamate	glutamate	NN
cord-310847-63gh2tg4	379	37	filaments	filament	NNS
cord-310847-63gh2tg4	379	38	(	(	-LRB-
cord-310847-63gh2tg4	379	39	PLGA	PLGA	NNP
cord-310847-63gh2tg4	379	40	)	)	-RRB-
cord-310847-63gh2tg4	379	41	,	,	,
cord-310847-63gh2tg4	379	42	PDGA	PDGA	NNP
cord-310847-63gh2tg4	379	43	filaments	filament	NNS
cord-310847-63gh2tg4	379	44	or	or	CC
cord-310847-63gh2tg4	379	45	poly	poly	NNP
cord-310847-63gh2tg4	379	46	-	-	HYPH
cord-310847-63gh2tg4	379	47	γ	γ	NNP
cord-310847-63gh2tg4	379	48	-	-	HYPH
cord-310847-63gh2tg4	379	49	L	l	NN
cord-310847-63gh2tg4	379	50	-	-	HYPH
cord-310847-63gh2tg4	379	51	D	d	NN
cord-310847-63gh2tg4	379	52	-	-	HYPH
cord-310847-63gh2tg4	379	53	glutamate	glutamate	NN
cord-310847-63gh2tg4	379	54	(	(	-LRB-
cord-310847-63gh2tg4	379	55	PLDGA	PLDGA	NNP
cord-310847-63gh2tg4	379	56	)	)	-RRB-
cord-310847-63gh2tg4	379	57	filaments	filament	NNS
cord-310847-63gh2tg4	379	58	.	.	.
cord-310847-63gh2tg4	380	1	135	135	CD
cord-310847-63gh2tg4	381	1	The	the	DT
cord-310847-63gh2tg4	381	2	production	production	NN
cord-310847-63gh2tg4	381	3	and	and	CC
cord-310847-63gh2tg4	381	4	maintenance	maintenance	NN
cord-310847-63gh2tg4	381	5	of	of	IN
cord-310847-63gh2tg4	381	6	sufficient	sufficient	JJ
cord-310847-63gh2tg4	381	7	D	d	NN
cord-310847-63gh2tg4	381	8	-	-	HYPH
cord-310847-63gh2tg4	381	9	glutamate	glutamate	NN
cord-310847-63gh2tg4	381	10	pool	pool	NN
cord-310847-63gh2tg4	381	11	levels	level	NNS
cord-310847-63gh2tg4	381	12	required	require	VBN
cord-310847-63gh2tg4	381	13	for	for	IN
cord-310847-63gh2tg4	381	14	the	the	DT
cord-310847-63gh2tg4	381	15	normal	normal	JJ
cord-310847-63gh2tg4	381	16	bacterial	bacterial	JJ
cord-310847-63gh2tg4	381	17	growth	growth	NN
cord-310847-63gh2tg4	381	18	is	be	VBZ
cord-310847-63gh2tg4	381	19	controlled	control	VBN
cord-310847-63gh2tg4	381	20	by	by	IN
cord-310847-63gh2tg4	381	21	the	the	DT
cord-310847-63gh2tg4	381	22	glutamate	glutamate	NN
cord-310847-63gh2tg4	381	23	racemase	racemase	NN
cord-310847-63gh2tg4	381	24	,	,	,
cord-310847-63gh2tg4	381	25	which	which	WDT
cord-310847-63gh2tg4	381	26	is	be	VBZ
cord-310847-63gh2tg4	381	27	a	a	DT
cord-310847-63gh2tg4	381	28	member	member	NN
cord-310847-63gh2tg4	381	29	of	of	IN
cord-310847-63gh2tg4	381	30	the	the	DT
cord-310847-63gh2tg4	381	31	cofactor	cofactor	NN
cord-310847-63gh2tg4	381	32	-	-	HYPH
cord-310847-63gh2tg4	381	33	independent	independent	JJ
cord-310847-63gh2tg4	381	34	,	,	,
cord-310847-63gh2tg4	381	35	twothiol	twothiol	NNP
cord-310847-63gh2tg4	381	36	-	-	HYPH
cord-310847-63gh2tg4	381	37	based	base	VBN
cord-310847-63gh2tg4	381	38	family	family	NN
cord-310847-63gh2tg4	381	39	of	of	IN
cord-310847-63gh2tg4	381	40	amino	amino	JJ
cord-310847-63gh2tg4	381	41	acid	acid	NN
cord-310847-63gh2tg4	381	42	racemases	racemase	NNS
cord-310847-63gh2tg4	381	43	.	.	.
cord-310847-63gh2tg4	382	1	140	140	CD
cord-310847-63gh2tg4	383	1	This	this	DT
cord-310847-63gh2tg4	383	2	enzyme	enzyme	NN
cord-310847-63gh2tg4	383	3	is	be	VBZ
cord-310847-63gh2tg4	383	4	conserved	conserve	VBN
cord-310847-63gh2tg4	383	5	and	and	CC
cord-310847-63gh2tg4	383	6	essential	essential	JJ
cord-310847-63gh2tg4	383	7	for	for	IN
cord-310847-63gh2tg4	383	8	growth	growth	NN
cord-310847-63gh2tg4	383	9	across	across	IN
cord-310847-63gh2tg4	383	10	the	the	DT
cord-310847-63gh2tg4	383	11	bacterial	bacterial	JJ
cord-310847-63gh2tg4	383	12	kingdom	kingdom	NN
cord-310847-63gh2tg4	383	13	and	and	CC
cord-310847-63gh2tg4	383	14	has	have	VBZ
cord-310847-63gh2tg4	383	15	a	a	DT
cord-310847-63gh2tg4	383	16	conserved	conserved	JJ
cord-310847-63gh2tg4	383	17	overall	overall	JJ
cord-310847-63gh2tg4	383	18	topology	topology	NN
cord-310847-63gh2tg4	383	19	and	and	CC
cord-310847-63gh2tg4	383	20	active	active	JJ
cord-310847-63gh2tg4	383	21	site	site	NN
cord-310847-63gh2tg4	383	22	architecture	architecture	NN
cord-310847-63gh2tg4	383	23	.	.	.
cord-310847-63gh2tg4	384	1	Therefore	therefore	RB
cord-310847-63gh2tg4	384	2	,	,	,
cord-310847-63gh2tg4	384	3	it	-PRON-	PRP
cord-310847-63gh2tg4	384	4	represents	represent	VBZ
cord-310847-63gh2tg4	384	5	an	an	DT
cord-310847-63gh2tg4	384	6	attractive	attractive	JJ
cord-310847-63gh2tg4	384	7	target	target	NN
cord-310847-63gh2tg4	384	8	for	for	IN
cord-310847-63gh2tg4	384	9	the	the	DT
cord-310847-63gh2tg4	384	10	development	development	NN
cord-310847-63gh2tg4	384	11	of	of	IN
cord-310847-63gh2tg4	384	12	specific	specific	JJ
cord-310847-63gh2tg4	384	13	inhibitors	inhibitor	NNS
cord-310847-63gh2tg4	384	14	that	that	WDT
cord-310847-63gh2tg4	384	15	could	could	MD
cord-310847-63gh2tg4	384	16	act	act	VB
cord-310847-63gh2tg4	384	17	as	as	IN
cord-310847-63gh2tg4	384	18	possible	possible	JJ
cord-310847-63gh2tg4	384	19	therapeutic	therapeutic	JJ
cord-310847-63gh2tg4	384	20	agents	agent	NNS
cord-310847-63gh2tg4	384	21	.	.	.
cord-310847-63gh2tg4	385	1	140	140	CD
cord-310847-63gh2tg4	386	1	In	in	IN
cord-310847-63gh2tg4	386	2	Gram	gram	NN
cord-310847-63gh2tg4	386	3	-	-	HYPH
cord-310847-63gh2tg4	386	4	negative	negative	JJ
cord-310847-63gh2tg4	386	5	bacteria	bacteria	NNS
cord-310847-63gh2tg4	386	6	,	,	,
cord-310847-63gh2tg4	386	7	the	the	DT
cord-310847-63gh2tg4	386	8	complex	complex	NN
cord-310847-63gh2tg4	386	9	responsible	responsible	JJ
cord-310847-63gh2tg4	386	10	for	for	IN
cord-310847-63gh2tg4	386	11	the	the	DT
cord-310847-63gh2tg4	386	12	polyglutamate	polyglutamate	NNP
cord-310847-63gh2tg4	386	13	synthesis	synthesis	NN
cord-310847-63gh2tg4	386	14	is	be	VBZ
cord-310847-63gh2tg4	386	15	encoded	encode	VBN
cord-310847-63gh2tg4	386	16	in	in	IN
cord-310847-63gh2tg4	386	17	specific	specific	JJ
cord-310847-63gh2tg4	386	18	loci	locus	NNS
cord-310847-63gh2tg4	386	19	.	.	.
cord-310847-63gh2tg4	387	1	If	if	IN
cord-310847-63gh2tg4	387	2	the	the	DT
cord-310847-63gh2tg4	387	3	PGA	PGA	NNP
cord-310847-63gh2tg4	387	4	is	be	VBZ
cord-310847-63gh2tg4	387	5	associated	associate	VBN
cord-310847-63gh2tg4	387	6	with	with	IN
cord-310847-63gh2tg4	387	7	the	the	DT
cord-310847-63gh2tg4	387	8	bacterial	bacterial	JJ
cord-310847-63gh2tg4	387	9	surface	surface	NN
cord-310847-63gh2tg4	387	10	and	and	CC
cord-310847-63gh2tg4	387	11	forms	form	VBZ
cord-310847-63gh2tg4	387	12	a	a	DT
cord-310847-63gh2tg4	387	13	capsule	capsule	NN
cord-310847-63gh2tg4	387	14	,	,	,
cord-310847-63gh2tg4	387	15	then	then	RB
cord-310847-63gh2tg4	387	16	the	the	DT
cord-310847-63gh2tg4	387	17	corresponding	corresponding	JJ
cord-310847-63gh2tg4	387	18	genes	gene	NNS
cord-310847-63gh2tg4	387	19	are	be	VBP
cord-310847-63gh2tg4	387	20	named	name	VBN
cord-310847-63gh2tg4	387	21	cap	cap	NN
cord-310847-63gh2tg4	387	22	(	(	-LRB-
cord-310847-63gh2tg4	387	23	for	for	IN
cord-310847-63gh2tg4	387	24	"	"	``
cord-310847-63gh2tg4	387	25	capsule	capsule	NN
cord-310847-63gh2tg4	387	26	"	"	''
cord-310847-63gh2tg4	387	27	)	)	-RRB-
cord-310847-63gh2tg4	387	28	;	;	:
cord-310847-63gh2tg4	387	29	however	however	RB
cord-310847-63gh2tg4	387	30	,	,	,
cord-310847-63gh2tg4	387	31	if	if	IN
cord-310847-63gh2tg4	387	32	the	the	DT
cord-310847-63gh2tg4	387	33	PGA	PGA	NNP
cord-310847-63gh2tg4	387	34	is	be	VBZ
cord-310847-63gh2tg4	387	35	released	release	VBN
cord-310847-63gh2tg4	387	36	,	,	,
cord-310847-63gh2tg4	387	37	then	then	RB
cord-310847-63gh2tg4	387	38	the	the	DT
cord-310847-63gh2tg4	387	39	corresponding	corresponding	JJ
cord-310847-63gh2tg4	387	40	genes	gene	NNS
cord-310847-63gh2tg4	387	41	are	be	VBP
cord-310847-63gh2tg4	387	42	named	name	VBN
cord-310847-63gh2tg4	387	43	pgs	pgs	CD
cord-310847-63gh2tg4	387	44	(	(	-LRB-
cord-310847-63gh2tg4	387	45	for	for	IN
cord-310847-63gh2tg4	387	46	polyglutamate	polyglutamate	NNP
cord-310847-63gh2tg4	387	47	synthase	synthase	NNP
cord-310847-63gh2tg4	387	48	)	)	-RRB-
cord-310847-63gh2tg4	387	49	.	.	.
cord-310847-63gh2tg4	388	1	135	135	CD
cord-310847-63gh2tg4	389	1	The	the	DT
cord-310847-63gh2tg4	389	2	minimal	minimal	JJ
cord-310847-63gh2tg4	389	3	gene	gene	NN
cord-310847-63gh2tg4	389	4	sets	set	NNS
cord-310847-63gh2tg4	389	5	contain	contain	VBP
cord-310847-63gh2tg4	389	6	four	four	CD
cord-310847-63gh2tg4	389	7	genes	gene	NNS
cord-310847-63gh2tg4	389	8	termed	term	VBN
cord-310847-63gh2tg4	389	9	cap	cap	NN
cord-310847-63gh2tg4	389	10	or	or	CC
cord-310847-63gh2tg4	389	11	pgs	pgs	NNP
cord-310847-63gh2tg4	389	12	B	B	NNP
cord-310847-63gh2tg4	389	13	,	,	,
cord-310847-63gh2tg4	389	14	C	C	NNP
cord-310847-63gh2tg4	389	15	,	,	,
cord-310847-63gh2tg4	389	16	A	A	NNP
cord-310847-63gh2tg4	389	17	and	and	CC
cord-310847-63gh2tg4	389	18	E	e	NN
cord-310847-63gh2tg4	389	19	,	,	,
cord-310847-63gh2tg4	389	20	with	with	IN
cord-310847-63gh2tg4	389	21	all	all	DT
cord-310847-63gh2tg4	389	22	cap	cap	NN
cord-310847-63gh2tg4	389	23	genes	gene	NNS
cord-310847-63gh2tg4	389	24	and	and	CC
cord-310847-63gh2tg4	389	25	the	the	DT
cord-310847-63gh2tg4	389	26	four	four	CD
cord-310847-63gh2tg4	389	27	pgs	pg	NNS
cord-310847-63gh2tg4	389	28	genes	gene	NNS
cord-310847-63gh2tg4	389	29	(	(	-LRB-
cord-310847-63gh2tg4	389	30	pgsB	pgsb	RB
cord-310847-63gh2tg4	389	31	,	,	,
cord-310847-63gh2tg4	389	32	pgsC	pgsc	XX
cord-310847-63gh2tg4	389	33	,	,	,
cord-310847-63gh2tg4	389	34	pgsAA	pgsaa	NN
cord-310847-63gh2tg4	389	35	,	,	,
cord-310847-63gh2tg4	389	36	pgsE	pgse	JJ
cord-310847-63gh2tg4	389	37	)	)	-RRB-
cord-310847-63gh2tg4	389	38	being	be	VBG
cord-310847-63gh2tg4	389	39	organized	organize	VBN
cord-310847-63gh2tg4	389	40	into	into	IN
cord-310847-63gh2tg4	389	41	operons	operon	NNS
cord-310847-63gh2tg4	389	42	.	.	.
cord-310847-63gh2tg4	390	1	141	141	CD
cord-310847-63gh2tg4	391	1	Since	since	IN
cord-310847-63gh2tg4	391	2	PGA	PGA	NNP
cord-310847-63gh2tg4	391	3	is	be	VBZ
cord-310847-63gh2tg4	391	4	an	an	DT
cord-310847-63gh2tg4	391	5	IDP	IDP	NNP
cord-310847-63gh2tg4	391	6	,	,	,
cord-310847-63gh2tg4	391	7	whose	whose	WP$
cord-310847-63gh2tg4	391	8	biochemical	biochemical	JJ
cord-310847-63gh2tg4	391	9	and	and	CC
cord-310847-63gh2tg4	391	10	biophysical	biophysical	JJ
cord-310847-63gh2tg4	391	11	properties	property	NNS
cord-310847-63gh2tg4	391	12	are	be	VBP
cord-310847-63gh2tg4	391	13	environment	environment	NN
cord-310847-63gh2tg4	391	14	-	-	HYPH
cord-310847-63gh2tg4	391	15	dependent	dependent	JJ
cord-310847-63gh2tg4	391	16	,	,	,
cord-310847-63gh2tg4	391	17	and	and	CC
cord-310847-63gh2tg4	391	18	since	since	IN
cord-310847-63gh2tg4	391	19	PGA	PGA	NNP
cord-310847-63gh2tg4	391	20	can	can	MD
cord-310847-63gh2tg4	391	21	be	be	VB
cord-310847-63gh2tg4	391	22	found	find	VBN
cord-310847-63gh2tg4	391	23	in	in	IN
cord-310847-63gh2tg4	391	24	an	an	DT
cord-310847-63gh2tg4	391	25	anchored	anchor	VBN
cord-310847-63gh2tg4	391	26	to	to	IN
cord-310847-63gh2tg4	391	27	the	the	DT
cord-310847-63gh2tg4	391	28	bacterial	bacterial	JJ
cord-310847-63gh2tg4	391	29	surface	surface	NN
cord-310847-63gh2tg4	391	30	form	form	NN
cord-310847-63gh2tg4	391	31	or	or	CC
cord-310847-63gh2tg4	391	32	in	in	IN
cord-310847-63gh2tg4	391	33	a	a	DT
cord-310847-63gh2tg4	391	34	released	release	VBN
cord-310847-63gh2tg4	391	35	form	form	NN
cord-310847-63gh2tg4	391	36	,	,	,
cord-310847-63gh2tg4	391	37	this	this	DT
cord-310847-63gh2tg4	391	38	biopolymer	biopolymer	NN
cord-310847-63gh2tg4	391	39	can	can	MD
cord-310847-63gh2tg4	391	40	play	play	VB
cord-310847-63gh2tg4	391	41	different	different	JJ
cord-310847-63gh2tg4	391	42	roles	role	NNS
cord-310847-63gh2tg4	391	43	in	in	IN
cord-310847-63gh2tg4	391	44	different	different	JJ
cord-310847-63gh2tg4	391	45	organisms	organism	NNS
cord-310847-63gh2tg4	391	46	and	and	CC
cord-310847-63gh2tg4	391	47	in	in	IN
cord-310847-63gh2tg4	391	48	different	different	JJ
cord-310847-63gh2tg4	391	49	environments	environment	NNS
cord-310847-63gh2tg4	391	50	.	.	.
cord-310847-63gh2tg4	392	1	135	135	CD
cord-310847-63gh2tg4	393	1	For	for	IN
cord-310847-63gh2tg4	393	2	example	example	NN
cord-310847-63gh2tg4	393	3	,	,	,
cord-310847-63gh2tg4	393	4	when	when	WRB
cord-310847-63gh2tg4	393	5	anchored	anchor	VBN
cord-310847-63gh2tg4	393	6	to	to	IN
cord-310847-63gh2tg4	393	7	the	the	DT
cord-310847-63gh2tg4	393	8	bacterial	bacterial	JJ
cord-310847-63gh2tg4	393	9	surface	surface	NN
cord-310847-63gh2tg4	393	10	,	,	,
cord-310847-63gh2tg4	393	11	PGA	PGA	NNP
cord-310847-63gh2tg4	393	12	forms	form	VBZ
cord-310847-63gh2tg4	393	13	a	a	DT
cord-310847-63gh2tg4	393	14	capsule	capsule	NN
cord-310847-63gh2tg4	393	15	and	and	CC
cord-310847-63gh2tg4	393	16	act	act	VB
cord-310847-63gh2tg4	393	17	as	as	IN
cord-310847-63gh2tg4	393	18	a	a	DT
cord-310847-63gh2tg4	393	19	virulence	virulence	NN
cord-310847-63gh2tg4	393	20	factor	factor	NN
cord-310847-63gh2tg4	393	21	.	.	.
cord-310847-63gh2tg4	394	1	135	135	CD
cord-310847-63gh2tg4	394	2	,	,	,
cord-310847-63gh2tg4	394	3	142	142	CD
cord-310847-63gh2tg4	395	1	In	in	IN
cord-310847-63gh2tg4	395	2	fact	fact	NN
cord-310847-63gh2tg4	395	3	,	,	,
cord-310847-63gh2tg4	395	4	the	the	DT
cord-310847-63gh2tg4	395	5	virulence	virulence	NN
cord-310847-63gh2tg4	395	6	of	of	IN
cord-310847-63gh2tg4	395	7	Bacillus	bacillus	NN
cord-310847-63gh2tg4	395	8	anthracis	anthracis	NN
cord-310847-63gh2tg4	395	9	(	(	-LRB-
cord-310847-63gh2tg4	395	10	a	a	DT
cord-310847-63gh2tg4	395	11	Gram	gram	NN
cord-310847-63gh2tg4	395	12	-	-	HYPH
cord-310847-63gh2tg4	395	13	positive	positive	JJ
cord-310847-63gh2tg4	395	14	sporulating	sporulating	NN
cord-310847-63gh2tg4	395	15	bacterium	bacterium	NN
cord-310847-63gh2tg4	395	16	,	,	,
cord-310847-63gh2tg4	395	17	which	which	WDT
cord-310847-63gh2tg4	395	18	is	be	VBZ
cord-310847-63gh2tg4	395	19	the	the	DT
cord-310847-63gh2tg4	395	20	causal	causal	JJ
cord-310847-63gh2tg4	395	21	agent	agent	NN
cord-310847-63gh2tg4	395	22	of	of	IN
cord-310847-63gh2tg4	395	23	anthrax	anthrax	NN
cord-310847-63gh2tg4	395	24	)	)	-RRB-
cord-310847-63gh2tg4	395	25	was	be	VBD
cord-310847-63gh2tg4	395	26	found	find	VBN
cord-310847-63gh2tg4	395	27	to	to	TO
cord-310847-63gh2tg4	395	28	be	be	VB
cord-310847-63gh2tg4	395	29	determined	determine	VBN
cord-310847-63gh2tg4	395	30	by	by	IN
cord-310847-63gh2tg4	395	31	its	-PRON-	PRP$
cord-310847-63gh2tg4	395	32	capsule	capsule	NN
cord-310847-63gh2tg4	395	33	composed	compose	VBN
cord-310847-63gh2tg4	395	34	solely	solely	RB
cord-310847-63gh2tg4	395	35	of	of	IN
cord-310847-63gh2tg4	395	36	PGA	PGA	NNP
cord-310847-63gh2tg4	395	37	.	.	.
cord-310847-63gh2tg4	396	1	143	143	CD
cord-310847-63gh2tg4	397	1	Similarly	similarly	RB
cord-310847-63gh2tg4	397	2	,	,	,
cord-310847-63gh2tg4	397	3	the	the	DT
cord-310847-63gh2tg4	397	4	virulence	virulence	NN
cord-310847-63gh2tg4	397	5	of	of	IN
cord-310847-63gh2tg4	397	6	Staphylococcus	Staphylococcus	NNP
cord-310847-63gh2tg4	397	7	epidermidis	epidermidi	NNS
cord-310847-63gh2tg4	397	8	(	(	-LRB-
cord-310847-63gh2tg4	397	9	another	another	DT
cord-310847-63gh2tg4	397	10	Gram	gram	NN
cord-310847-63gh2tg4	397	11	-	-	HYPH
cord-310847-63gh2tg4	397	12	positive	positive	JJ
cord-310847-63gh2tg4	397	13	bacterium	bacterium	NN
cord-310847-63gh2tg4	397	14	that	that	WDT
cord-310847-63gh2tg4	397	15	causes	cause	VBZ
cord-310847-63gh2tg4	397	16	severe	severe	JJ
cord-310847-63gh2tg4	397	17	infection	infection	NN
cord-310847-63gh2tg4	397	18	after	after	IN
cord-310847-63gh2tg4	397	19	penetrating	penetrate	VBG
cord-310847-63gh2tg4	397	20	the	the	DT
cord-310847-63gh2tg4	397	21	protective	protective	JJ
cord-310847-63gh2tg4	397	22	epidermal	epidermal	JJ
cord-310847-63gh2tg4	397	23	barriers	barrier	NNS
cord-310847-63gh2tg4	397	24	of	of	IN
cord-310847-63gh2tg4	397	25	the	the	DT
cord-310847-63gh2tg4	397	26	human	human	JJ
cord-310847-63gh2tg4	397	27	body	body	NN
cord-310847-63gh2tg4	397	28	)	)	-RRB-
cord-310847-63gh2tg4	397	29	is	be	VBZ
cord-310847-63gh2tg4	397	30	dependent	dependent	JJ
cord-310847-63gh2tg4	397	31	on	on	IN
cord-310847-63gh2tg4	397	32	the	the	DT
cord-310847-63gh2tg4	397	33	PGA	PGA	NNP
cord-310847-63gh2tg4	397	34	-	-	HYPH
cord-310847-63gh2tg4	397	35	based	base	VBN
cord-310847-63gh2tg4	397	36	capsule	capsule	NN
cord-310847-63gh2tg4	397	37	.	.	.
cord-310847-63gh2tg4	398	1	144	144	CD
cord-310847-63gh2tg4	399	1	Furthermore	furthermore	RB
cord-310847-63gh2tg4	399	2	,	,	,
cord-310847-63gh2tg4	399	3	PGA	PGA	NNP
cord-310847-63gh2tg4	399	4	in	in	IN
cord-310847-63gh2tg4	399	5	capsules	capsule	NNS
cord-310847-63gh2tg4	399	6	of	of	IN
cord-310847-63gh2tg4	399	7	these	these	DT
cord-310847-63gh2tg4	399	8	bacteria	bacteria	NNS
cord-310847-63gh2tg4	399	9	consists	consist	VBZ
cord-310847-63gh2tg4	399	10	of	of	IN
cord-310847-63gh2tg4	399	11	either	either	CC
cord-310847-63gh2tg4	399	12	a	a	DT
cord-310847-63gh2tg4	399	13	mixture	mixture	NN
cord-310847-63gh2tg4	399	14	of	of	IN
cord-310847-63gh2tg4	399	15	L	l	NN
cord-310847-63gh2tg4	399	16	-	-	:
cord-310847-63gh2tg4	399	17	and	and	CC
cord-310847-63gh2tg4	399	18	D	D	NNP
cord-310847-63gh2tg4	399	19	-	-	HYPH
cord-310847-63gh2tg4	399	20	enantiomers	enantiomer	NNS
cord-310847-63gh2tg4	399	21	(	(	-LRB-
cord-310847-63gh2tg4	399	22	S.	S.	NNP
cord-310847-63gh2tg4	399	23	epidermidis	epidermidi	NNS
cord-310847-63gh2tg4	399	24	)	)	-RRB-
cord-310847-63gh2tg4	400	1	144	144	CD
cord-310847-63gh2tg4	400	2	or	or	CC
cord-310847-63gh2tg4	400	3	solely	solely	RB
cord-310847-63gh2tg4	400	4	D	d	NN
cord-310847-63gh2tg4	400	5	-	-	HYPH
cord-310847-63gh2tg4	400	6	enantiomer	enantiomer	JJ
cord-310847-63gh2tg4	400	7	(	(	-LRB-
cord-310847-63gh2tg4	400	8	B.	B.	NNP
cord-310847-63gh2tg4	400	9	anthracis	anthracis	NNP
cord-310847-63gh2tg4	400	10	)	)	-RRB-
cord-310847-63gh2tg4	400	11	,	,	,
cord-310847-63gh2tg4	400	12	145	145	CD
cord-310847-63gh2tg4	400	13	which	which	WDT
cord-310847-63gh2tg4	400	14	makes	make	VBZ
cord-310847-63gh2tg4	400	15	them	-PRON-	PRP
cord-310847-63gh2tg4	400	16	particularly	particularly	RB
cord-310847-63gh2tg4	400	17	non	non	JJ
cord-310847-63gh2tg4	400	18	-	-	JJ
cord-310847-63gh2tg4	400	19	immunogenic	immunogenic	JJ
cord-310847-63gh2tg4	400	20	.	.	.
cord-310847-63gh2tg4	401	1	135	135	CD
cord-310847-63gh2tg4	402	1	The	the	DT
cord-310847-63gh2tg4	402	2	released	release	VBN
cord-310847-63gh2tg4	402	3	form	form	NN
cord-310847-63gh2tg4	402	4	of	of	IN
cord-310847-63gh2tg4	402	5	PGA	PGA	NNP
cord-310847-63gh2tg4	402	6	is	be	VBZ
cord-310847-63gh2tg4	402	7	used	use	VBN
cord-310847-63gh2tg4	402	8	by	by	IN
cord-310847-63gh2tg4	402	9	the	the	DT
cord-310847-63gh2tg4	402	10	producing	produce	VBG
cord-310847-63gh2tg4	402	11	organism	organism	NN
cord-310847-63gh2tg4	402	12	for	for	IN
cord-310847-63gh2tg4	402	13	rather	rather	RB
cord-310847-63gh2tg4	402	14	different	different	JJ
cord-310847-63gh2tg4	402	15	purposes	purpose	NNS
cord-310847-63gh2tg4	402	16	,	,	,
cord-310847-63gh2tg4	402	17	starting	start	VBG
cord-310847-63gh2tg4	402	18	from	from	IN
cord-310847-63gh2tg4	402	19	the	the	DT
cord-310847-63gh2tg4	402	20	sequestration	sequestration	NN
cord-310847-63gh2tg4	402	21	of	of	IN
cord-310847-63gh2tg4	402	22	toxic	toxic	JJ
cord-310847-63gh2tg4	402	23	metal	metal	NN
cord-310847-63gh2tg4	402	24	ions	ion	NNS
cord-310847-63gh2tg4	402	25	that	that	WDT
cord-310847-63gh2tg4	402	26	increases	increase	VBZ
cord-310847-63gh2tg4	402	27	the	the	DT
cord-310847-63gh2tg4	402	28	resistance	resistance	NN
cord-310847-63gh2tg4	402	29	of	of	IN
cord-310847-63gh2tg4	402	30	some	some	DT
cord-310847-63gh2tg4	402	31	soil	soil	NN
cord-310847-63gh2tg4	402	32	bacteria	bacteria	NNS
cord-310847-63gh2tg4	402	33	to	to	IN
cord-310847-63gh2tg4	402	34	harsh	harsh	JJ
cord-310847-63gh2tg4	402	35	conditions	condition	NNS
cord-310847-63gh2tg4	402	36	,	,	,
cord-310847-63gh2tg4	402	37	146	146	CD
cord-310847-63gh2tg4	402	38	to	to	IN
cord-310847-63gh2tg4	402	39	serving	serve	VBG
cord-310847-63gh2tg4	402	40	as	as	IN
cord-310847-63gh2tg4	402	41	a	a	DT
cord-310847-63gh2tg4	402	42	source	source	NN
cord-310847-63gh2tg4	402	43	of	of	IN
cord-310847-63gh2tg4	402	44	glutamate	glutamate	NN
cord-310847-63gh2tg4	402	45	for	for	IN
cord-310847-63gh2tg4	402	46	bacteria	bacteria	NNS
cord-310847-63gh2tg4	402	47	in	in	IN
cord-310847-63gh2tg4	402	48	a	a	DT
cord-310847-63gh2tg4	402	49	starvation	starvation	NN
cord-310847-63gh2tg4	402	50	state	state	NN
cord-310847-63gh2tg4	402	51	during	during	IN
cord-310847-63gh2tg4	402	52	late	late	JJ
cord-310847-63gh2tg4	402	53	stationary	stationary	JJ
cord-310847-63gh2tg4	402	54	phase	phase	NN
cord-310847-63gh2tg4	402	55	,	,	,
cord-310847-63gh2tg4	402	56	147	147	CD
cord-310847-63gh2tg4	402	57	to	to	IN
cord-310847-63gh2tg4	402	58	playing	play	VBG
cord-310847-63gh2tg4	402	59	a	a	DT
cord-310847-63gh2tg4	402	60	role	role	NN
cord-310847-63gh2tg4	402	61	in	in	IN
cord-310847-63gh2tg4	402	62	decrease	decrease	NN
cord-310847-63gh2tg4	402	63	of	of	IN
cord-310847-63gh2tg4	402	64	the	the	DT
cord-310847-63gh2tg4	402	65	high	high	JJ
cord-310847-63gh2tg4	402	66	local	local	JJ
cord-310847-63gh2tg4	402	67	salt	salt	NN
cord-310847-63gh2tg4	402	68	concentrations	concentration	NNS
cord-310847-63gh2tg4	402	69	that	that	WDT
cord-310847-63gh2tg4	402	70	helps	help	VBZ
cord-310847-63gh2tg4	402	71	extremophilic	extremophilic	JJ
cord-310847-63gh2tg4	402	72	bacteria	bacteria	NNS
cord-310847-63gh2tg4	402	73	and	and	CC
cord-310847-63gh2tg4	402	74	archaea	archaea	NNS
cord-310847-63gh2tg4	402	75	to	to	TO
cord-310847-63gh2tg4	402	76	survive	survive	VB
cord-310847-63gh2tg4	402	77	in	in	IN
cord-310847-63gh2tg4	402	78	a	a	DT
cord-310847-63gh2tg4	402	79	hostile	hostile	JJ
cord-310847-63gh2tg4	402	80	environment	environment	NN
cord-310847-63gh2tg4	402	81	,	,	,
cord-310847-63gh2tg4	402	82	148	148	CD
cord-310847-63gh2tg4	402	83	,	,	,
cord-310847-63gh2tg4	402	84	149	149	CD
cord-310847-63gh2tg4	402	85	and	and	CC
cord-310847-63gh2tg4	402	86	in	in	IN
cord-310847-63gh2tg4	402	87	Hydra	Hydra	NNP
cord-310847-63gh2tg4	402	88	,	,	,
cord-310847-63gh2tg4	402	89	to	to	TO
cord-310847-63gh2tg4	402	90	control	control	VB
cord-310847-63gh2tg4	402	91	explosion	explosion	NN
cord-310847-63gh2tg4	402	92	of	of	IN
cord-310847-63gh2tg4	402	93	the	the	DT
cord-310847-63gh2tg4	402	94	special	special	JJ
cord-310847-63gh2tg4	402	95	stringing	stringing	NN
cord-310847-63gh2tg4	402	96	cells	cell	NNS
cord-310847-63gh2tg4	402	97	,	,	,
cord-310847-63gh2tg4	402	98	nematocysts	nematocyst	NNS
cord-310847-63gh2tg4	402	99	,	,	,
cord-310847-63gh2tg4	402	100	that	that	WDT
cord-310847-63gh2tg4	402	101	are	be	VBP
cord-310847-63gh2tg4	402	102	used	use	VBN
cord-310847-63gh2tg4	402	103	to	to	TO
cord-310847-63gh2tg4	402	104	capture	capture	VB
cord-310847-63gh2tg4	402	105	prey	prey	NN
cord-310847-63gh2tg4	402	106	,	,	,
cord-310847-63gh2tg4	402	107	for	for	IN
cord-310847-63gh2tg4	402	108	locomotion	locomotion	NN
cord-310847-63gh2tg4	402	109	and	and	CC
cord-310847-63gh2tg4	402	110	for	for	IN
cord-310847-63gh2tg4	402	111	defense	defense	NN
cord-310847-63gh2tg4	402	112	.	.	.
cord-310847-63gh2tg4	403	1	150	150	CD
cord-310847-63gh2tg4	404	1	In	in	IN
cord-310847-63gh2tg4	404	2	addition	addition	NN
cord-310847-63gh2tg4	404	3	to	to	TO
cord-310847-63gh2tg4	404	4	have	have	VB
cord-310847-63gh2tg4	404	5	multiple	multiple	JJ
cord-310847-63gh2tg4	404	6	functional	functional	JJ
cord-310847-63gh2tg4	404	7	roles	role	NNS
cord-310847-63gh2tg4	404	8	,	,	,
cord-310847-63gh2tg4	404	9	bacterially	bacterially	RB
cord-310847-63gh2tg4	404	10	produced	produce	VBD
cord-310847-63gh2tg4	404	11	PGA	PGA	NNP
cord-310847-63gh2tg4	404	12	has	have	VBZ
cord-310847-63gh2tg4	404	13	found	find	VBN
cord-310847-63gh2tg4	404	14	its	-PRON-	PRP$
cord-310847-63gh2tg4	404	15	way	way	NN
cord-310847-63gh2tg4	404	16	to	to	TO
cord-310847-63gh2tg4	404	17	serve	serve	VB
cord-310847-63gh2tg4	404	18	as	as	IN
cord-310847-63gh2tg4	404	19	an	an	DT
cord-310847-63gh2tg4	404	20	important	important	JJ
cord-310847-63gh2tg4	404	21	biodegradable	biodegradable	JJ
cord-310847-63gh2tg4	404	22	component	component	NN
cord-310847-63gh2tg4	404	23	151	151	CD
cord-310847-63gh2tg4	404	24	with	with	IN
cord-310847-63gh2tg4	404	25	multifarious	multifarious	JJ
cord-310847-63gh2tg4	404	26	potential	potential	JJ
cord-310847-63gh2tg4	404	27	applications	application	NNS
cord-310847-63gh2tg4	404	28	in	in	IN
cord-310847-63gh2tg4	404	29	foods	food	NNS
cord-310847-63gh2tg4	404	30	,	,	,
cord-310847-63gh2tg4	404	31	pharmaceuticals	pharmaceutical	NNS
cord-310847-63gh2tg4	404	32	,	,	,
cord-310847-63gh2tg4	404	33	healthcare	healthcare	NN
cord-310847-63gh2tg4	404	34	,	,	,
cord-310847-63gh2tg4	404	35	water	water	NN
cord-310847-63gh2tg4	404	36	treatment	treatment	NN
cord-310847-63gh2tg4	404	37	and	and	CC
cord-310847-63gh2tg4	404	38	other	other	JJ
cord-310847-63gh2tg4	404	39	fields	field	NNS
cord-310847-63gh2tg4	404	40	.	.	.
cord-310847-63gh2tg4	405	1	152	152	CD
cord-310847-63gh2tg4	406	1	,	,	,
cord-310847-63gh2tg4	406	2	153	153	CD
cord-310847-63gh2tg4	406	3	A	a	DT
cord-310847-63gh2tg4	406	4	large	large	JJ
cord-310847-63gh2tg4	406	5	commercial	commercial	JJ
cord-310847-63gh2tg4	406	6	advantage	advantage	NN
cord-310847-63gh2tg4	406	7	of	of	IN
cord-310847-63gh2tg4	406	8	PGA	PGA	NNP
cord-310847-63gh2tg4	406	9	is	be	VBZ
cord-310847-63gh2tg4	406	10	that	that	IN
cord-310847-63gh2tg4	406	11	this	this	DT
cord-310847-63gh2tg4	406	12	Although	although	IN
cord-310847-63gh2tg4	406	13	some	some	DT
cord-310847-63gh2tg4	406	14	amount	amount	NN
cord-310847-63gh2tg4	406	15	of	of	IN
cord-310847-63gh2tg4	406	16	glutamic	glutamic	NN
cord-310847-63gh2tg4	406	17	acid	acid	NN
cord-310847-63gh2tg4	406	18	residues	residue	NNS
cord-310847-63gh2tg4	406	19	is	be	VBZ
cord-310847-63gh2tg4	406	20	crucial	crucial	JJ
cord-310847-63gh2tg4	406	21	for	for	IN
cord-310847-63gh2tg4	406	22	the	the	DT
cord-310847-63gh2tg4	406	23	structure	structure	NN
cord-310847-63gh2tg4	406	24	and	and	CC
cord-310847-63gh2tg4	406	25	function	function	NN
cord-310847-63gh2tg4	406	26	of	of	IN
cord-310847-63gh2tg4	406	27	ordered	order	VBN
cord-310847-63gh2tg4	406	28	proteins	protein	NNS
cord-310847-63gh2tg4	406	29	/	/	SYM
cord-310847-63gh2tg4	406	30	domains	domain	NNS
cord-310847-63gh2tg4	406	31	,	,	,
cord-310847-63gh2tg4	406	32	when	when	WRB
cord-310847-63gh2tg4	406	33	a	a	DT
cord-310847-63gh2tg4	406	34	protein	protein	NN
cord-310847-63gh2tg4	406	35	or	or	CC
cord-310847-63gh2tg4	406	36	a	a	DT
cord-310847-63gh2tg4	406	37	peptide	peptide	NN
cord-310847-63gh2tg4	406	38	contains	contain	VBZ
cord-310847-63gh2tg4	406	39	a	a	DT
cord-310847-63gh2tg4	406	40	large	large	JJ
cord-310847-63gh2tg4	406	41	number	number	NN
cord-310847-63gh2tg4	406	42	of	of	IN
cord-310847-63gh2tg4	406	43	glutamic	glutamic	NN
cord-310847-63gh2tg4	406	44	acid	acid	NN
cord-310847-63gh2tg4	406	45	residues	residue	NNS
cord-310847-63gh2tg4	406	46	and	and	CC
cord-310847-63gh2tg4	406	47	,	,	,
cord-310847-63gh2tg4	406	48	as	as	IN
cord-310847-63gh2tg4	406	49	a	a	DT
cord-310847-63gh2tg4	406	50	consequence	consequence	NN
cord-310847-63gh2tg4	406	51	,	,	,
cord-310847-63gh2tg4	406	52	possesses	possess	VBZ
cord-310847-63gh2tg4	406	53	a	a	DT
cord-310847-63gh2tg4	406	54	small	small	JJ
cord-310847-63gh2tg4	406	55	number	number	NN
cord-310847-63gh2tg4	406	56	of	of	IN
cord-310847-63gh2tg4	406	57	hydrophobic	hydrophobic	JJ
cord-310847-63gh2tg4	406	58	residues	residue	NNS
cord-310847-63gh2tg4	406	59	,	,	,
cord-310847-63gh2tg4	406	60	it	-PRON-	PRP
cord-310847-63gh2tg4	406	61	is	be	VBZ
cord-310847-63gh2tg4	406	62	likely	likely	JJ
cord-310847-63gh2tg4	406	63	to	to	TO
cord-310847-63gh2tg4	406	64	be	be	VB
cord-310847-63gh2tg4	406	65	disordered	disorder	VBN
cord-310847-63gh2tg4	406	66	at	at	IN
cord-310847-63gh2tg4	406	67	physiological	physiological	JJ
cord-310847-63gh2tg4	406	68	pH	ph	NN
cord-310847-63gh2tg4	406	69	due	due	JJ
cord-310847-63gh2tg4	406	70	to	to	IN
cord-310847-63gh2tg4	406	71	strong	strong	JJ
cord-310847-63gh2tg4	406	72	charge	charge	NN
cord-310847-63gh2tg4	406	73	-	-	HYPH
cord-310847-63gh2tg4	406	74	charge	charge	NN
cord-310847-63gh2tg4	406	75	repulsion	repulsion	NN
cord-310847-63gh2tg4	406	76	and	and	CC
cord-310847-63gh2tg4	406	77	weak	weak	JJ
cord-310847-63gh2tg4	406	78	hydrophobic	hydrophobic	JJ
cord-310847-63gh2tg4	406	79	attraction	attraction	NN
cord-310847-63gh2tg4	406	80	.	.	.
cord-310847-63gh2tg4	407	1	An	an	DT
cord-310847-63gh2tg4	407	2	illustrative	illustrative	JJ
cord-310847-63gh2tg4	407	3	example	example	NN
cord-310847-63gh2tg4	407	4	of	of	IN
cord-310847-63gh2tg4	407	5	such	such	JJ
cord-310847-63gh2tg4	407	6	charge	charge	NN
cord-310847-63gh2tg4	407	7	-	-	HYPH
cord-310847-63gh2tg4	407	8	infused	infuse	VBN
cord-310847-63gh2tg4	407	9	proteins	protein	NNS
cord-310847-63gh2tg4	407	10	is	be	VBZ
cord-310847-63gh2tg4	407	11	Glurich	Glurich	NNP
cord-310847-63gh2tg4	407	12	human	human	JJ
cord-310847-63gh2tg4	407	13	prothymosin	prothymosin	NNS
cord-310847-63gh2tg4	407	14	α	α	NNP
cord-310847-63gh2tg4	407	15	,	,	,
cord-310847-63gh2tg4	407	16	in	in	IN
cord-310847-63gh2tg4	407	17	which	which	WDT
cord-310847-63gh2tg4	407	18	64	64	CD
cord-310847-63gh2tg4	407	19	out	out	IN
cord-310847-63gh2tg4	407	20	of	of	IN
cord-310847-63gh2tg4	407	21	111	111	CD
cord-310847-63gh2tg4	407	22	residues	residue	NNS
cord-310847-63gh2tg4	407	23	are	be	VBP
cord-310847-63gh2tg4	407	24	charged	charge	VBN
cord-310847-63gh2tg4	407	25	(	(	-LRB-
cord-310847-63gh2tg4	407	26	there	there	EX
cord-310847-63gh2tg4	407	27	are	be	VBP
cord-310847-63gh2tg4	407	28	19	19	CD
cord-310847-63gh2tg4	407	29	Asp	Asp	NNP
cord-310847-63gh2tg4	407	30	,	,	,
cord-310847-63gh2tg4	407	31	35	35	CD
cord-310847-63gh2tg4	407	32	Glu	Glu	NNP
cord-310847-63gh2tg4	407	33	,	,	,
cord-310847-63gh2tg4	407	34	2	2	CD
cord-310847-63gh2tg4	407	35	Arg	arg	NN
cord-310847-63gh2tg4	407	36	and	and	CC
cord-310847-63gh2tg4	407	37	8	8	CD
cord-310847-63gh2tg4	407	38	Lys	Lys	NNP
cord-310847-63gh2tg4	407	39	residues	residue	NNS
cord-310847-63gh2tg4	407	40	)	)	-RRB-
cord-310847-63gh2tg4	407	41	,	,	,
cord-310847-63gh2tg4	407	42	the	the	DT
cord-310847-63gh2tg4	407	43	overall	overall	JJ
cord-310847-63gh2tg4	407	44	content	content	NN
cord-310847-63gh2tg4	407	45	of	of	IN
cord-310847-63gh2tg4	407	46	hydrophobic	hydrophobic	JJ
cord-310847-63gh2tg4	407	47	residues	residue	NNS
cord-310847-63gh2tg4	407	48	(	(	-LRB-
cord-310847-63gh2tg4	407	49	Leu	Leu	NNP
cord-310847-63gh2tg4	407	50	,	,	,
cord-310847-63gh2tg4	407	51	Ile	Ile	NNP
cord-310847-63gh2tg4	407	52	and	and	CC
cord-310847-63gh2tg4	407	53	Val	Val	NNP
cord-310847-63gh2tg4	407	54	)	)	-RRB-
cord-310847-63gh2tg4	407	55	is	be	VBZ
cord-310847-63gh2tg4	407	56	very	very	RB
cord-310847-63gh2tg4	407	57	low	low	JJ
cord-310847-63gh2tg4	407	58	,	,	,
cord-310847-63gh2tg4	407	59	and	and	CC
cord-310847-63gh2tg4	407	60	aromatic	aromatic	JJ
cord-310847-63gh2tg4	407	61	residues	residue	NNS
cord-310847-63gh2tg4	407	62	(	(	-LRB-
cord-310847-63gh2tg4	407	63	Trp	Trp	NNP
cord-310847-63gh2tg4	407	64	,	,	,
cord-310847-63gh2tg4	407	65	Tyr	Tyr	NNP
cord-310847-63gh2tg4	407	66	,	,	,
cord-310847-63gh2tg4	407	67	Phe	Phe	NNP
cord-310847-63gh2tg4	407	68	and	and	CC
cord-310847-63gh2tg4	407	69	His	-PRON-	PRP$
cord-310847-63gh2tg4	407	70	)	)	-RRB-
cord-310847-63gh2tg4	407	71	and	and	CC
cord-310847-63gh2tg4	407	72	cystein	cystein	NNP
cord-310847-63gh2tg4	407	73	are	be	VBP
cord-310847-63gh2tg4	407	74	absent	absent	JJ
cord-310847-63gh2tg4	407	75	.	.	.
cord-310847-63gh2tg4	408	1	133	133	CD
cord-310847-63gh2tg4	409	1	Based	base	VBN
cord-310847-63gh2tg4	409	2	on	on	IN
cord-310847-63gh2tg4	409	3	this	this	DT
cord-310847-63gh2tg4	409	4	amino	amino	NN
cord-310847-63gh2tg4	409	5	acid	acid	NN
cord-310847-63gh2tg4	409	6	composition	composition	NN
cord-310847-63gh2tg4	409	7	,	,	,
cord-310847-63gh2tg4	409	8	it	-PRON-	PRP
cord-310847-63gh2tg4	409	9	was	be	VBD
cord-310847-63gh2tg4	409	10	not	not	RB
cord-310847-63gh2tg4	409	11	a	a	DT
cord-310847-63gh2tg4	409	12	big	big	JJ
cord-310847-63gh2tg4	409	13	surprise	surprise	NN
cord-310847-63gh2tg4	409	14	to	to	TO
cord-310847-63gh2tg4	409	15	find	find	VB
cord-310847-63gh2tg4	409	16	that	that	IN
cord-310847-63gh2tg4	409	17	prothymosin	prothymosin	NNP
cord-310847-63gh2tg4	409	18	α	α	NNP
cord-310847-63gh2tg4	409	19	behaved	behave	VBD
cord-310847-63gh2tg4	409	20	as	as	IN
cord-310847-63gh2tg4	409	21	a	a	DT
cord-310847-63gh2tg4	409	22	highly	highly	RB
cord-310847-63gh2tg4	409	23	disordered	disordered	JJ
cord-310847-63gh2tg4	409	24	coil	coil	NN
cord-310847-63gh2tg4	409	25	-	-	HYPH
cord-310847-63gh2tg4	409	26	like	like	JJ
cord-310847-63gh2tg4	409	27	chain	chain	NN
cord-310847-63gh2tg4	409	28	,	,	,
cord-310847-63gh2tg4	409	29	since	since	IN
cord-310847-63gh2tg4	409	30	one	one	PRP
cord-310847-63gh2tg4	409	31	can	can	MD
cord-310847-63gh2tg4	409	32	not	not	RB
cord-310847-63gh2tg4	409	33	expect	expect	VB
cord-310847-63gh2tg4	409	34	that	that	IN
cord-310847-63gh2tg4	409	35	a	a	DT
cord-310847-63gh2tg4	409	36	highly	highly	RB
cord-310847-63gh2tg4	409	37	charged	charge	VBN
cord-310847-63gh2tg4	409	38	polypeptide	polypeptide	NN
cord-310847-63gh2tg4	409	39	(	(	-LRB-
cord-310847-63gh2tg4	409	40	that	that	DT
cord-310847-63gh2tg4	409	41	contains	contain	VBZ
cord-310847-63gh2tg4	409	42	60	60	CD
cord-310847-63gh2tg4	409	43	%	%	NN
cord-310847-63gh2tg4	409	44	of	of	IN
cord-310847-63gh2tg4	409	45	Glu+Asp	Glu+Asp	NNP
cord-310847-63gh2tg4	409	46	residues	residue	NNS
cord-310847-63gh2tg4	409	47	)	)	-RRB-
cord-310847-63gh2tg4	409	48	will	will	MD
cord-310847-63gh2tg4	409	49	have	have	VB
cord-310847-63gh2tg4	409	50	a	a	DT
cord-310847-63gh2tg4	409	51	strong	strong	JJ
cord-310847-63gh2tg4	409	52	tendency	tendency	NN
cord-310847-63gh2tg4	409	53	to	to	TO
cord-310847-63gh2tg4	409	54	fold	fold	VB
cord-310847-63gh2tg4	409	55	under	under	IN
cord-310847-63gh2tg4	409	56	physiological	physiological	JJ
cord-310847-63gh2tg4	409	57	conditions	condition	NNS
cord-310847-63gh2tg4	409	58	.	.	.
cord-310847-63gh2tg4	410	1	133	133	CD
cord-310847-63gh2tg4	410	2	,	,	,
cord-310847-63gh2tg4	410	3	134	134	CD
cord-310847-63gh2tg4	411	1	The	the	DT
cord-310847-63gh2tg4	411	2	lack	lack	NN
cord-310847-63gh2tg4	411	3	of	of	IN
cord-310847-63gh2tg4	411	4	stable	stable	JJ
cord-310847-63gh2tg4	411	5	structure	structure	NN
cord-310847-63gh2tg4	411	6	also	also	RB
cord-310847-63gh2tg4	411	7	explains	explain	VBZ
cord-310847-63gh2tg4	411	8	the	the	DT
cord-310847-63gh2tg4	411	9	extreme	extreme	JJ
cord-310847-63gh2tg4	411	10	thermal	thermal	JJ
cord-310847-63gh2tg4	411	11	and	and	CC
cord-310847-63gh2tg4	411	12	acid	acid	JJ
cord-310847-63gh2tg4	411	13	stability	stability	NN
cord-310847-63gh2tg4	411	14	of	of	IN
cord-310847-63gh2tg4	411	15	prothymosin	prothymosin	NNP
cord-310847-63gh2tg4	411	16	α	α	NNP
cord-310847-63gh2tg4	411	17	,	,	,
cord-310847-63gh2tg4	411	18	since	since	IN
cord-310847-63gh2tg4	411	19	one	one	PRP
cord-310847-63gh2tg4	411	20	can	can	MD
cord-310847-63gh2tg4	411	21	not	not	RB
cord-310847-63gh2tg4	411	22	break	break	VB
cord-310847-63gh2tg4	411	23	what	what	WP
cord-310847-63gh2tg4	411	24	is	be	VBZ
cord-310847-63gh2tg4	411	25	non	non	JJ
cord-310847-63gh2tg4	411	26	-	-	JJ
cord-310847-63gh2tg4	411	27	existent	existent	JJ
cord-310847-63gh2tg4	411	28	.	.	.
cord-310847-63gh2tg4	412	1	133	133	CD
cord-310847-63gh2tg4	413	1	The	the	DT
cord-310847-63gh2tg4	413	2	peculiar	peculiar	JJ
cord-310847-63gh2tg4	413	3	amino	amino	NN
cord-310847-63gh2tg4	413	4	acid	acid	NN
cord-310847-63gh2tg4	413	5	composition	composition	NN
cord-310847-63gh2tg4	413	6	of	of	IN
cord-310847-63gh2tg4	413	7	prothymosin	prothymosin	NNP
cord-310847-63gh2tg4	413	8	α	α	NNP
cord-310847-63gh2tg4	413	9	,	,	,
cord-310847-63gh2tg4	413	10	this	this	DT
cord-310847-63gh2tg4	413	11	biologically	biologically	RB
cord-310847-63gh2tg4	413	12	active	active	JJ
cord-310847-63gh2tg4	413	13	random	random	JJ
cord-310847-63gh2tg4	413	14	coil	coil	NN
cord-310847-63gh2tg4	413	15	,	,	,
cord-310847-63gh2tg4	413	16	was	be	VBD
cord-310847-63gh2tg4	413	17	one	one	CD
cord-310847-63gh2tg4	413	18	of	of	IN
cord-310847-63gh2tg4	413	19	the	the	DT
cord-310847-63gh2tg4	413	20	defining	define	VBG
cord-310847-63gh2tg4	413	21	factors	factor	NNS
cord-310847-63gh2tg4	413	22	behind	behind	IN
cord-310847-63gh2tg4	413	23	the	the	DT
cord-310847-63gh2tg4	413	24	charge	charge	NN
cord-310847-63gh2tg4	413	25	-	-	HYPH
cord-310847-63gh2tg4	413	26	hydropathy	hydropathy	JJ
cord-310847-63gh2tg4	413	27	plot	plot	NN
cord-310847-63gh2tg4	413	28	(	(	-LRB-
cord-310847-63gh2tg4	413	29	CH	ch	NN
cord-310847-63gh2tg4	413	30	-	-	HYPH
cord-310847-63gh2tg4	413	31	plot	plot	NN
cord-310847-63gh2tg4	413	32	)	)	-RRB-
cord-310847-63gh2tg4	413	33	development	development	NN
cord-310847-63gh2tg4	413	34	.	.	.
cord-310847-63gh2tg4	414	1	5	5	LS
cord-310847-63gh2tg4	415	1	In	in	IN
cord-310847-63gh2tg4	415	2	fact	fact	NN
cord-310847-63gh2tg4	415	3	,	,	,
cord-310847-63gh2tg4	415	4	based	base	VBN
cord-310847-63gh2tg4	415	5	on	on	IN
cord-310847-63gh2tg4	415	6	the	the	DT
cord-310847-63gh2tg4	415	7	analysis	analysis	NN
cord-310847-63gh2tg4	415	8	of	of	IN
cord-310847-63gh2tg4	415	9	prothymosin	prothymosin	NNP
cord-310847-63gh2tg4	415	10	α	α	NNP
cord-310847-63gh2tg4	415	11	and	and	CC
cord-310847-63gh2tg4	415	12	of	of	IN
cord-310847-63gh2tg4	415	13	90	90	CD
cord-310847-63gh2tg4	415	14	other	other	JJ
cord-310847-63gh2tg4	415	15	non	non	JJ
cord-310847-63gh2tg4	415	16	-	-	JJ
cord-310847-63gh2tg4	415	17	globular	globular	JJ
cord-310847-63gh2tg4	415	18	proteins	protein	NNS
cord-310847-63gh2tg4	415	19	that	that	WDT
cord-310847-63gh2tg4	415	20	lacked	lack	VBD
cord-310847-63gh2tg4	415	21	almost	almost	RB
cord-310847-63gh2tg4	415	22	any	any	DT
cord-310847-63gh2tg4	415	23	ordered	order	VBN
cord-310847-63gh2tg4	415	24	secondary	secondary	JJ
cord-310847-63gh2tg4	415	25	structure	structure	NN
cord-310847-63gh2tg4	415	26	under	under	IN
cord-310847-63gh2tg4	415	27	physiological	physiological	JJ
cord-310847-63gh2tg4	415	28	conditions	condition	NNS
cord-310847-63gh2tg4	415	29	in	in	IN
cord-310847-63gh2tg4	415	30	vitro	vitro	FW
cord-310847-63gh2tg4	415	31	,	,	,
cord-310847-63gh2tg4	415	32	it	-PRON-	PRP
cord-310847-63gh2tg4	415	33	was	be	VBD
cord-310847-63gh2tg4	415	34	concluded	conclude	VBN
cord-310847-63gh2tg4	415	35	that	that	IN
cord-310847-63gh2tg4	415	36	a	a	DT
cord-310847-63gh2tg4	415	37	combination	combination	NN
cord-310847-63gh2tg4	415	38	of	of	IN
cord-310847-63gh2tg4	415	39	high	high	JJ
cord-310847-63gh2tg4	415	40	net	net	JJ
cord-310847-63gh2tg4	415	41	charge	charge	NN
cord-310847-63gh2tg4	415	42	and	and	CC
cord-310847-63gh2tg4	415	43	low	low	JJ
cord-310847-63gh2tg4	415	44	hydropathy	hydropathy	NNP
cord-310847-63gh2tg4	415	45	represents	represent	VBZ
cord-310847-63gh2tg4	415	46	the	the	DT
cord-310847-63gh2tg4	415	47	necessary	necessary	JJ
cord-310847-63gh2tg4	415	48	and	and	CC
cord-310847-63gh2tg4	415	49	sufficient	sufficient	JJ
cord-310847-63gh2tg4	415	50	factor	factor	NN
cord-310847-63gh2tg4	415	51	for	for	IN
cord-310847-63gh2tg4	415	52	a	a	DT
cord-310847-63gh2tg4	415	53	polypeptide	polypeptide	NN
cord-310847-63gh2tg4	415	54	to	to	TO
cord-310847-63gh2tg4	415	55	behave	behave	VB
cord-310847-63gh2tg4	415	56	as	as	IN
cord-310847-63gh2tg4	415	57	a	a	DT
cord-310847-63gh2tg4	415	58	natively	natively	RB
cord-310847-63gh2tg4	415	59	unfolded	unfold	VBN
cord-310847-63gh2tg4	415	60	protein	protein	NN
cord-310847-63gh2tg4	415	61	.	.	.
cord-310847-63gh2tg4	416	1	5	5	LS
cord-310847-63gh2tg4	417	1	Strategically	strategically	RB
cord-310847-63gh2tg4	417	2	positioned	position	VBN
cord-310847-63gh2tg4	417	3	glutamic	glutamic	NN
cord-310847-63gh2tg4	417	4	acid	acid	NN
cord-310847-63gh2tg4	417	5	residues	residue	NNS
cord-310847-63gh2tg4	417	6	can	can	MD
cord-310847-63gh2tg4	417	7	modulate	modulate	VB
cord-310847-63gh2tg4	417	8	conformational	conformational	JJ
cord-310847-63gh2tg4	417	9	stability	stability	NN
cord-310847-63gh2tg4	417	10	and	and	CC
cord-310847-63gh2tg4	417	11	function	function	NN
cord-310847-63gh2tg4	417	12	of	of	IN
cord-310847-63gh2tg4	417	13	ordered	order	VBN
cord-310847-63gh2tg4	417	14	proteins	protein	NNS
cord-310847-63gh2tg4	417	15	too	too	RB
cord-310847-63gh2tg4	417	16	.	.	.
cord-310847-63gh2tg4	418	1	In	in	IN
cord-310847-63gh2tg4	418	2	fact	fact	NN
cord-310847-63gh2tg4	418	3	,	,	,
cord-310847-63gh2tg4	418	4	the	the	DT
cord-310847-63gh2tg4	418	5	role	role	NN
cord-310847-63gh2tg4	418	6	of	of	IN
cord-310847-63gh2tg4	418	7	a	a	DT
cord-310847-63gh2tg4	418	8	glutamic	glutamic	NN
cord-310847-63gh2tg4	418	9	/	/	SYM
cord-310847-63gh2tg4	418	10	aspartic	aspartic	JJ
cord-310847-63gh2tg4	418	11	acid	acid	NN
cord-310847-63gh2tg4	418	12	cluster	cluster	NN
cord-310847-63gh2tg4	418	13	located	locate	VBN
cord-310847-63gh2tg4	418	14	outside	outside	IN
cord-310847-63gh2tg4	418	15	the	the	DT
cord-310847-63gh2tg4	418	16	Ca	Ca	NNP
cord-310847-63gh2tg4	418	17	2	2	CD
cord-310847-63gh2tg4	418	18	+	+	SYM
cord-310847-63gh2tg4	418	19	-binding	-binding	NN
cord-310847-63gh2tg4	418	20	site	site	NN
cord-310847-63gh2tg4	418	21	,	,	,
cord-310847-63gh2tg4	418	22	and	and	CC
cord-310847-63gh2tg4	418	23	of	of	IN
cord-310847-63gh2tg4	418	24	the	the	DT
cord-310847-63gh2tg4	418	25	N	n	CD
cord-310847-63gh2tg4	418	26	-	-	HYPH
cord-310847-63gh2tg4	418	27	terminal	terminal	NN
cord-310847-63gh2tg4	418	28	Glu1	Glu1	NNP
cord-310847-63gh2tg4	418	29	residue	residue	NN
cord-310847-63gh2tg4	418	30	in	in	IN
cord-310847-63gh2tg4	418	31	destabilizing	destabilize	VBG
cord-310847-63gh2tg4	418	32	the	the	DT
cord-310847-63gh2tg4	418	33	structure	structure	NN
cord-310847-63gh2tg4	418	34	and	and	CC
cord-310847-63gh2tg4	418	35	weakening	weaken	VBG
cord-310847-63gh2tg4	418	36	the	the	DT
cord-310847-63gh2tg4	418	37	calcium	calcium	NN
cord-310847-63gh2tg4	418	38	-	-	HYPH
cord-310847-63gh2tg4	418	39	binding	bind	VBG
cord-310847-63gh2tg4	418	40	capabilities	capability	NNS
cord-310847-63gh2tg4	418	41	of	of	IN
cord-310847-63gh2tg4	418	42	α	α	NN
cord-310847-63gh2tg4	418	43	-	-	HYPH
cord-310847-63gh2tg4	418	44	lactabumin	lactabumin	NNP
cord-310847-63gh2tg4	418	45	has	have	VBZ
cord-310847-63gh2tg4	418	46	been	be	VBN
cord-310847-63gh2tg4	418	47	already	already	RB
cord-310847-63gh2tg4	418	48	discussed	discuss	VBN
cord-310847-63gh2tg4	418	49	(	(	-LRB-
cord-310847-63gh2tg4	418	50	see	see	VB
cord-310847-63gh2tg4	418	51	above	above	RB
cord-310847-63gh2tg4	418	52	)	)	-RRB-
cord-310847-63gh2tg4	418	53	.	.	.
cord-310847-63gh2tg4	419	1	121	121	CD
cord-310847-63gh2tg4	419	2	,	,	,
cord-310847-63gh2tg4	419	3	125	125	CD
cord-310847-63gh2tg4	419	4	Therefore	therefore	RB
cord-310847-63gh2tg4	419	5	based	base	VBN
cord-310847-63gh2tg4	419	6	on	on	IN
cord-310847-63gh2tg4	419	7	these	these	DT
cord-310847-63gh2tg4	419	8	observations	observation	NNS
cord-310847-63gh2tg4	419	9	,	,	,
cord-310847-63gh2tg4	419	10	protein	protein	NN
cord-310847-63gh2tg4	419	11	regions	region	NNS
cord-310847-63gh2tg4	419	12	and	and	CC
cord-310847-63gh2tg4	419	13	whole	whole	JJ
cord-310847-63gh2tg4	419	14	proteins	protein	NNS
cord-310847-63gh2tg4	419	15	enriched	enrich	VBN
cord-310847-63gh2tg4	419	16	in	in	IN
cord-310847-63gh2tg4	419	17	glutamic	glutamic	NN
cord-310847-63gh2tg4	419	18	acids	acid	NNS
cord-310847-63gh2tg4	419	19	are	be	VBP
cord-310847-63gh2tg4	419	20	expected	expect	VBN
cord-310847-63gh2tg4	419	21	to	to	TO
cord-310847-63gh2tg4	419	22	be	be	VB
cord-310847-63gh2tg4	419	23	substantially	substantially	RB
cord-310847-63gh2tg4	419	24	disordered	disordered	JJ
cord-310847-63gh2tg4	419	25	.	.	.
cord-310847-63gh2tg4	420	1	Poly	Poly	NNP
cord-310847-63gh2tg4	420	2	-	-	HYPH
cord-310847-63gh2tg4	420	3	γ	γ	NN
cord-310847-63gh2tg4	420	4	-	-	HYPH
cord-310847-63gh2tg4	420	5	glutamate	glutamate	NN
cord-310847-63gh2tg4	420	6	(	(	-LRB-
cord-310847-63gh2tg4	420	7	PGA	PGA	NNP
cord-310847-63gh2tg4	420	8	)	)	-RRB-
cord-310847-63gh2tg4	420	9	is	be	VBZ
cord-310847-63gh2tg4	420	10	a	a	DT
cord-310847-63gh2tg4	420	11	natural	natural	JJ
cord-310847-63gh2tg4	420	12	homopolymer	homopolymer	NN
cord-310847-63gh2tg4	420	13	synthesized	synthesize	VBN
cord-310847-63gh2tg4	420	14	by	by	IN
cord-310847-63gh2tg4	420	15	several	several	JJ
cord-310847-63gh2tg4	420	16	bacteria	bacteria	NNS
cord-310847-63gh2tg4	420	17	,	,	,
cord-310847-63gh2tg4	420	18	one	one	CD
cord-310847-63gh2tg4	420	19	archaea	archaea	JJ
cord-310847-63gh2tg4	420	20	(	(	-LRB-
cord-310847-63gh2tg4	420	21	Natrialba	Natrialba	NNP
cord-310847-63gh2tg4	420	22	aegyptiaca	aegyptiaca	NN
cord-310847-63gh2tg4	420	23	)	)	-RRB-
cord-310847-63gh2tg4	420	24	and	and	CC
cord-310847-63gh2tg4	420	25	one	one	CD
cord-310847-63gh2tg4	420	26	eukaryote	eukaryote	NN
cord-310847-63gh2tg4	420	27	(	(	-LRB-
cord-310847-63gh2tg4	420	28	Cnidaria	Cnidaria	NNP
cord-310847-63gh2tg4	420	29	)	)	-RRB-
cord-310847-63gh2tg4	420	30	.	.	.
cord-310847-63gh2tg4	421	1	135	135	CD
cord-310847-63gh2tg4	421	2	One	one	CD
cord-310847-63gh2tg4	421	3	of	of	IN
cord-310847-63gh2tg4	421	4	the	the	DT
cord-310847-63gh2tg4	421	5	most	most	RBS
cord-310847-63gh2tg4	421	6	known	know	VBN
cord-310847-63gh2tg4	421	7	sources	source	NNS
cord-310847-63gh2tg4	421	8	of	of	IN
cord-310847-63gh2tg4	421	9	PGA	PGA	NNP
cord-310847-63gh2tg4	421	10	is	be	VBZ
cord-310847-63gh2tg4	421	11	the	the	DT
cord-310847-63gh2tg4	421	12	Japanese	japanese	JJ
cord-310847-63gh2tg4	421	13	specialty	specialty	NN
cord-310847-63gh2tg4	421	14	natto	natto	NN
cord-310847-63gh2tg4	421	15	,	,	,
cord-310847-63gh2tg4	421	16	a	a	DT
cord-310847-63gh2tg4	421	17	fermentation	fermentation	NN
cord-310847-63gh2tg4	421	18	product	product	NN
cord-310847-63gh2tg4	421	19	made	make	VBN
cord-310847-63gh2tg4	421	20	by	by	IN
cord-310847-63gh2tg4	421	21	Bacillus	bacillus	NN
cord-310847-63gh2tg4	421	22	subtilis	subtili	NNS
cord-310847-63gh2tg4	421	23	grown	grow	VBN
cord-310847-63gh2tg4	421	24	on	on	IN
cord-310847-63gh2tg4	421	25	soybean	soybean	NN
cord-310847-63gh2tg4	421	26	.	.	.
cord-310847-63gh2tg4	422	1	135	135	CD
cord-310847-63gh2tg4	422	2	PGA	PGA	NNP
cord-310847-63gh2tg4	422	3	is	be	VBZ
cord-310847-63gh2tg4	422	4	a	a	DT
cord-310847-63gh2tg4	422	5	highly	highly	RB
cord-310847-63gh2tg4	422	6	soluble	soluble	JJ
cord-310847-63gh2tg4	422	7	polyanionic	polyanionic	NN
cord-310847-63gh2tg4	422	8	polymer	polymer	NN
cord-310847-63gh2tg4	422	9	that	that	WDT
cord-310847-63gh2tg4	422	10	sequesters	sequester	VBZ
cord-310847-63gh2tg4	422	11	water	water	NN
cord-310847-63gh2tg4	422	12	molecules	molecule	NNS
cord-310847-63gh2tg4	422	13	and	and	CC
cord-310847-63gh2tg4	422	14	can	can	MD
cord-310847-63gh2tg4	422	15	be	be	VB
cord-310847-63gh2tg4	422	16	found	find	VBN
cord-310847-63gh2tg4	422	17	in	in	IN
cord-310847-63gh2tg4	422	18	surface	surface	NN
cord-310847-63gh2tg4	422	19	-	-	HYPH
cord-310847-63gh2tg4	422	20	bound	bind	VBN
cord-310847-63gh2tg4	422	21	and	and	CC
cord-310847-63gh2tg4	422	22	released	release	VBN
cord-310847-63gh2tg4	422	23	forms	form	NNS
cord-310847-63gh2tg4	422	24	.	.	.
cord-310847-63gh2tg4	423	1	In	in	IN
cord-310847-63gh2tg4	423	2	structural	structural	JJ
cord-310847-63gh2tg4	423	3	studies	study	NNS
cord-310847-63gh2tg4	423	4	,	,	,
cord-310847-63gh2tg4	423	5	polyglutamic	polyglutamic	JJ
cord-310847-63gh2tg4	423	6	acid	acid	NN
cord-310847-63gh2tg4	423	7	is	be	VBZ
cord-310847-63gh2tg4	423	8	traditionally	traditionally	RB
cord-310847-63gh2tg4	423	9	used	use	VBN
cord-310847-63gh2tg4	423	10	as	as	IN
cord-310847-63gh2tg4	423	11	a	a	DT
cord-310847-63gh2tg4	423	12	biopolymer	biopolymer	NN
cord-310847-63gh2tg4	423	13	with	with	IN
cord-310847-63gh2tg4	423	14	a	a	DT
cord-310847-63gh2tg4	423	15	well	well	RB
cord-310847-63gh2tg4	423	16	-	-	HYPH
cord-310847-63gh2tg4	423	17	characterized	characterize	VBN
cord-310847-63gh2tg4	423	18	secondary	secondary	JJ
cord-310847-63gh2tg4	423	19	structure	structure	NN
cord-310847-63gh2tg4	423	20	response	response	NN
cord-310847-63gh2tg4	423	21	to	to	IN
cord-310847-63gh2tg4	423	22	changes	change	NNS
cord-310847-63gh2tg4	423	23	in	in	IN
cord-310847-63gh2tg4	423	24	the	the	DT
cord-310847-63gh2tg4	423	25	environmental	environmental	JJ
cord-310847-63gh2tg4	423	26	pH	ph	NN
cord-310847-63gh2tg4	423	27	,	,	,
cord-310847-63gh2tg4	423	28	where	where	WRB
cord-310847-63gh2tg4	423	29	PGA	PGA	NNP
cord-310847-63gh2tg4	423	30	is	be	VBZ
cord-310847-63gh2tg4	423	31	in	in	IN
cord-310847-63gh2tg4	423	32	a	a	DT
cord-310847-63gh2tg4	423	33	random	random	JJ
cord-310847-63gh2tg4	423	34	coil	coil	NN
cord-310847-63gh2tg4	423	35	-	-	HYPH
cord-310847-63gh2tg4	423	36	like	like	JJ
cord-310847-63gh2tg4	423	37	conformation	conformation	NN
cord-310847-63gh2tg4	423	38	at	at	IN
cord-310847-63gh2tg4	423	39	neutral	neutral	JJ
cord-310847-63gh2tg4	423	40	pH	pH	NNP
cord-310847-63gh2tg4	423	41	,	,	,
cord-310847-63gh2tg4	423	42	but	but	CC
cord-310847-63gh2tg4	423	43	gains	gain	NNS
cord-310847-63gh2tg4	423	44	monomeric	monomeric	JJ
cord-310847-63gh2tg4	423	45	α	α	NN
cord-310847-63gh2tg4	423	46	-	-	HYPH
cord-310847-63gh2tg4	423	47	helical	helical	JJ
cord-310847-63gh2tg4	423	48	structure	structure	NN
cord-310847-63gh2tg4	423	49	at	at	IN
cord-310847-63gh2tg4	423	50	acidic	acidic	JJ
cord-310847-63gh2tg4	423	51	pH	pH	NNP
cord-310847-63gh2tg4	423	52	and	and	CC
cord-310847-63gh2tg4	423	53	is	be	VBZ
cord-310847-63gh2tg4	423	54	transformed	transform	VBN
cord-310847-63gh2tg4	423	55	into	into	IN
cord-310847-63gh2tg4	423	56	a	a	DT
cord-310847-63gh2tg4	423	57	β	β	NN
cord-310847-63gh2tg4	423	58	-	-	HYPH
cord-310847-63gh2tg4	423	59	sheet	sheet	NN
cord-310847-63gh2tg4	423	60	structure	structure	NN
cord-310847-63gh2tg4	423	61	at	at	IN
cord-310847-63gh2tg4	423	62	alkaline	alkaline	JJ
cord-310847-63gh2tg4	423	63	pH.	ph.	NN
cord-310847-63gh2tg4	423	64	[	[	-LRB-
cord-310847-63gh2tg4	423	65	136	136	CD
cord-310847-63gh2tg4	423	66	]	]	-RRB-
cord-310847-63gh2tg4	423	67	[	[	-LRB-
cord-310847-63gh2tg4	423	68	137	137	CD
cord-310847-63gh2tg4	423	69	]	]	-RRB-
cord-310847-63gh2tg4	423	70	[	[	-LRB-
cord-310847-63gh2tg4	423	71	138	138	CD
cord-310847-63gh2tg4	423	72	]	]	-RRB-
cord-310847-63gh2tg4	424	1	Curiously	curiously	RB
cord-310847-63gh2tg4	424	2	,	,	,
cord-310847-63gh2tg4	424	3	the	the	DT
cord-310847-63gh2tg4	424	4	addition	addition	NN
cord-310847-63gh2tg4	424	5	of	of	IN
cord-310847-63gh2tg4	424	6	polylysine	polylysine	NN
cord-310847-63gh2tg4	424	7	to	to	IN
cord-310847-63gh2tg4	424	8	an	an	DT
cord-310847-63gh2tg4	424	9	aqueous	aqueous	JJ
cord-310847-63gh2tg4	424	10	solution	solution	NN
cord-310847-63gh2tg4	424	11	of	of	IN
cord-310847-63gh2tg4	424	12	polyglutamic	polyglutamic	JJ
cord-310847-63gh2tg4	424	13	acid	acid	NN
cord-310847-63gh2tg4	424	14	homopolypeptide	homopolypeptide	RB
cord-310847-63gh2tg4	424	15	at	at	IN
cord-310847-63gh2tg4	424	16	EBD	EBD	NNP
cord-310847-63gh2tg4	424	17	is	be	VBZ
cord-310847-63gh2tg4	424	18	not	not	RB
cord-310847-63gh2tg4	424	19	a	a	DT
cord-310847-63gh2tg4	424	20	structurally	structurally	RB
cord-310847-63gh2tg4	424	21	stable	stable	JJ
cord-310847-63gh2tg4	424	22	entity	entity	NN
cord-310847-63gh2tg4	424	23	in	in	IN
cord-310847-63gh2tg4	424	24	the	the	DT
cord-310847-63gh2tg4	424	25	conventional	conventional	JJ
cord-310847-63gh2tg4	424	26	sense	sense	NN
cord-310847-63gh2tg4	424	27	,	,	,
cord-310847-63gh2tg4	424	28	since	since	IN
cord-310847-63gh2tg4	424	29	for	for	IN
cord-310847-63gh2tg4	424	30	this	this	DT
cord-310847-63gh2tg4	424	31	protein	protein	NN
cord-310847-63gh2tg4	424	32	region	region	NN
cord-310847-63gh2tg4	424	33	there	there	EX
cord-310847-63gh2tg4	424	34	are	be	VBP
cord-310847-63gh2tg4	424	35	no	no	DT
cord-310847-63gh2tg4	424	36	folded	fold	VBN
cord-310847-63gh2tg4	424	37	states	state	NNS
cord-310847-63gh2tg4	424	38	that	that	WDT
cord-310847-63gh2tg4	424	39	exist	exist	VBP
cord-310847-63gh2tg4	424	40	for	for	IN
cord-310847-63gh2tg4	424	41	any	any	DT
cord-310847-63gh2tg4	424	42	appreciable	appreciable	JJ
cord-310847-63gh2tg4	424	43	amount	amount	NN
cord-310847-63gh2tg4	424	44	of	of	IN
cord-310847-63gh2tg4	424	45	time	time	NN
cord-310847-63gh2tg4	424	46	.	.	.
cord-310847-63gh2tg4	425	1	Instead	instead	RB
cord-310847-63gh2tg4	425	2	,	,	,
cord-310847-63gh2tg4	425	3	the	the	DT
cord-310847-63gh2tg4	425	4	EBD	EBD	NNP
cord-310847-63gh2tg4	425	5	represents	represent	VBZ
cord-310847-63gh2tg4	425	6	a	a	DT
cord-310847-63gh2tg4	425	7	time	time	NN
cord-310847-63gh2tg4	425	8	-	-	HYPH
cord-310847-63gh2tg4	425	9	average	average	JJ
cord-310847-63gh2tg4	425	10	3D	3d	JJ
cord-310847-63gh2tg4	425	11	region	region	NN
cord-310847-63gh2tg4	425	12	of	of	IN
cord-310847-63gh2tg4	425	13	a	a	DT
cord-310847-63gh2tg4	425	14	protein	protein	NN
cord-310847-63gh2tg4	425	15	derived	derive	VBN
cord-310847-63gh2tg4	425	16	from	from	IN
cord-310847-63gh2tg4	425	17	the	the	DT
cord-310847-63gh2tg4	425	18	thermally	thermally	RB
cord-310847-63gh2tg4	425	19	driven	drive	VBN
cord-310847-63gh2tg4	425	20	motion	motion	NN
cord-310847-63gh2tg4	425	21	of	of	IN
cord-310847-63gh2tg4	425	22	certain	certain	JJ
cord-310847-63gh2tg4	425	23	polypeptide	polypeptide	NN
cord-310847-63gh2tg4	425	24	chains	chain	NNS
cord-310847-63gh2tg4	425	25	,	,	,
cord-310847-63gh2tg4	425	26	including	include	VBG
cord-310847-63gh2tg4	425	27	those	those	DT
cord-310847-63gh2tg4	425	28	that	that	WDT
cord-310847-63gh2tg4	425	29	are	be	VBP
cord-310847-63gh2tg4	425	30	part	part	NN
cord-310847-63gh2tg4	425	31	of	of	IN
cord-310847-63gh2tg4	425	32	an	an	DT
cord-310847-63gh2tg4	425	33	otherwise	otherwise	RB
cord-310847-63gh2tg4	425	34	stable	stable	JJ
cord-310847-63gh2tg4	425	35	folded	fold	VBN
cord-310847-63gh2tg4	425	36	protein	protein	NN
cord-310847-63gh2tg4	425	37	.	.	.
cord-310847-63gh2tg4	426	1	163	163	CD
cord-310847-63gh2tg4	427	1	Therefore	therefore	RB
cord-310847-63gh2tg4	427	2	,	,	,
cord-310847-63gh2tg4	427	3	the	the	DT
cord-310847-63gh2tg4	427	4	EBD	EBD	NNP
cord-310847-63gh2tg4	427	5	which	which	WDT
cord-310847-63gh2tg4	427	6	is	be	VBZ
cord-310847-63gh2tg4	427	7	defined	define	VBN
cord-310847-63gh2tg4	427	8	by	by	IN
cord-310847-63gh2tg4	427	9	the	the	DT
cord-310847-63gh2tg4	427	10	time	time	NN
cord-310847-63gh2tg4	427	11	-	-	HYPH
cord-310847-63gh2tg4	427	12	averaged	average	VBN
cord-310847-63gh2tg4	427	13	occupancy	occupancy	NN
cord-310847-63gh2tg4	427	14	of	of	IN
cord-310847-63gh2tg4	427	15	space	space	NN
cord-310847-63gh2tg4	427	16	by	by	IN
cord-310847-63gh2tg4	427	17	a	a	DT
cord-310847-63gh2tg4	427	18	polypeptide	polypeptide	NN
cord-310847-63gh2tg4	427	19	chain	chain	NN
cord-310847-63gh2tg4	427	20	,	,	,
cord-310847-63gh2tg4	427	21	can	can	MD
cord-310847-63gh2tg4	427	22	exclude	exclude	VB
cord-310847-63gh2tg4	427	23	lager	lager	NN
cord-310847-63gh2tg4	427	24	molecules	molecule	NNS
cord-310847-63gh2tg4	427	25	while	while	IN
cord-310847-63gh2tg4	427	26	allowing	allow	VBG
cord-310847-63gh2tg4	427	27	small	small	JJ
cord-310847-63gh2tg4	427	28	molecules	molecule	NNS
cord-310847-63gh2tg4	427	29	and	and	CC
cord-310847-63gh2tg4	427	30	water	water	NN
cord-310847-63gh2tg4	427	31	to	to	TO
cord-310847-63gh2tg4	427	32	move	move	VB
cord-310847-63gh2tg4	427	33	freely	freely	RB
cord-310847-63gh2tg4	427	34	through	through	IN
cord-310847-63gh2tg4	427	35	it	-PRON-	PRP
cord-310847-63gh2tg4	427	36	.	.	.
cord-310847-63gh2tg4	428	1	It	-PRON-	PRP
cord-310847-63gh2tg4	428	2	was	be	VBD
cord-310847-63gh2tg4	428	3	proposed	propose	VBN
cord-310847-63gh2tg4	428	4	that	that	IN
cord-310847-63gh2tg4	428	5	since	since	IN
cord-310847-63gh2tg4	428	6	functions	function	NNS
cord-310847-63gh2tg4	428	7	of	of	IN
cord-310847-63gh2tg4	428	8	EBD	EBD	NNP
cord-310847-63gh2tg4	428	9	depend	depend	VBP
cord-310847-63gh2tg4	428	10	on	on	IN
cord-310847-63gh2tg4	428	11	the	the	DT
cord-310847-63gh2tg4	428	12	intrinsically	intrinsically	RB
cord-310847-63gh2tg4	428	13	rapid	rapid	JJ
cord-310847-63gh2tg4	428	14	thermal	thermal	JJ
cord-310847-63gh2tg4	428	15	motion	motion	NN
cord-310847-63gh2tg4	428	16	of	of	IN
cord-310847-63gh2tg4	428	17	the	the	DT
cord-310847-63gh2tg4	428	18	polypeptide	polypeptide	NN
cord-310847-63gh2tg4	428	19	,	,	,
cord-310847-63gh2tg4	428	20	and	and	CC
cord-310847-63gh2tg4	428	21	the	the	DT
cord-310847-63gh2tg4	428	22	free	free	JJ
cord-310847-63gh2tg4	428	23	energy	energy	NN
cord-310847-63gh2tg4	428	24	changes	change	NNS
cord-310847-63gh2tg4	428	25	that	that	WDT
cord-310847-63gh2tg4	428	26	result	result	VBP
cord-310847-63gh2tg4	428	27	when	when	WRB
cord-310847-63gh2tg4	428	28	that	that	DT
cord-310847-63gh2tg4	428	29	motion	motion	NN
cord-310847-63gh2tg4	428	30	is	be	VBZ
cord-310847-63gh2tg4	428	31	confined	confine	VBN
cord-310847-63gh2tg4	428	32	,	,	,
cord-310847-63gh2tg4	428	33	this	this	DT
cord-310847-63gh2tg4	428	34	domain	domain	NN
cord-310847-63gh2tg4	428	35	can	can	MD
cord-310847-63gh2tg4	428	36	be	be	VB
cord-310847-63gh2tg4	428	37	used	use	VBN
cord-310847-63gh2tg4	428	38	to	to	TO
cord-310847-63gh2tg4	428	39	control	control	VB
cord-310847-63gh2tg4	428	40	binding	binding	JJ
cord-310847-63gh2tg4	428	41	events	event	NNS
cord-310847-63gh2tg4	428	42	,	,	,
cord-310847-63gh2tg4	428	43	confer	confer	VB
cord-310847-63gh2tg4	428	44	mechanical	mechanical	JJ
cord-310847-63gh2tg4	428	45	properties	property	NNS
cord-310847-63gh2tg4	428	46	,	,	,
cord-310847-63gh2tg4	428	47	and	and	CC
cord-310847-63gh2tg4	428	48	sterically	sterically	RB
cord-310847-63gh2tg4	428	49	control	control	VBP
cord-310847-63gh2tg4	428	50	molecular	molecular	JJ
cord-310847-63gh2tg4	428	51	interactions	interaction	NNS
cord-310847-63gh2tg4	428	52	.	.	.
cord-310847-63gh2tg4	429	1	163	163	CD
cord-310847-63gh2tg4	429	2	Obviously	obviously	RB
cord-310847-63gh2tg4	429	3	,	,	,
cord-310847-63gh2tg4	429	4	to	to	TO
cord-310847-63gh2tg4	429	5	be	be	VB
cord-310847-63gh2tg4	429	6	able	able	JJ
cord-310847-63gh2tg4	429	7	to	to	TO
cord-310847-63gh2tg4	429	8	serve	serve	VB
cord-310847-63gh2tg4	429	9	as	as	IN
cord-310847-63gh2tg4	429	10	an	an	DT
cord-310847-63gh2tg4	429	11	EBD	EBD	NNP
cord-310847-63gh2tg4	429	12	,	,	,
cord-310847-63gh2tg4	429	13	a	a	DT
cord-310847-63gh2tg4	429	14	given	give	VBN
cord-310847-63gh2tg4	429	15	fragment	fragment	NN
cord-310847-63gh2tg4	429	16	of	of	IN
cord-310847-63gh2tg4	429	17	a	a	DT
cord-310847-63gh2tg4	429	18	protein	protein	NN
cord-310847-63gh2tg4	429	19	has	have	VBZ
cord-310847-63gh2tg4	429	20	to	to	TO
cord-310847-63gh2tg4	429	21	possess	possess	VB
cord-310847-63gh2tg4	429	22	specific	specific	JJ
cord-310847-63gh2tg4	429	23	amino	amino	NN
cord-310847-63gh2tg4	429	24	acid	acid	NN
cord-310847-63gh2tg4	429	25	composition	composition	NN
cord-310847-63gh2tg4	429	26	that	that	WDT
cord-310847-63gh2tg4	429	27	would	would	MD
cord-310847-63gh2tg4	429	28	preclude	preclude	VB
cord-310847-63gh2tg4	429	29	it	-PRON-	PRP
cord-310847-63gh2tg4	429	30	from	from	IN
cord-310847-63gh2tg4	429	31	folding	fold	VBG
cord-310847-63gh2tg4	429	32	.	.	.
cord-310847-63gh2tg4	430	1	Therefore	therefore	RB
cord-310847-63gh2tg4	430	2	,	,	,
cord-310847-63gh2tg4	430	3	EBDs	ebd	NNS
cord-310847-63gh2tg4	430	4	are	be	VBP
cord-310847-63gh2tg4	430	5	expected	expect	VBN
cord-310847-63gh2tg4	430	6	to	to	TO
cord-310847-63gh2tg4	430	7	possess	possess	VB
cord-310847-63gh2tg4	430	8	low	low	JJ
cord-310847-63gh2tg4	430	9	hydropathy	hydropathy	JJ
cord-310847-63gh2tg4	430	10	and	and	CC
cord-310847-63gh2tg4	430	11	high	high	JJ
cord-310847-63gh2tg4	430	12	net	net	JJ
cord-310847-63gh2tg4	430	13	charge	charge	NN
cord-310847-63gh2tg4	430	14	;	;	:
cord-310847-63gh2tg4	430	15	i.e.	i.e.	FW
cord-310847-63gh2tg4	430	16	,	,	,
cord-310847-63gh2tg4	430	17	in	in	IN
cord-310847-63gh2tg4	430	18	the	the	DT
cord-310847-63gh2tg4	430	19	CH	ch	NN
cord-310847-63gh2tg4	430	20	-	-	HYPH
cord-310847-63gh2tg4	430	21	plot	plot	NN
cord-310847-63gh2tg4	430	22	,	,	,
cord-310847-63gh2tg4	430	23	they	-PRON-	PRP
cord-310847-63gh2tg4	430	24	can	can	MD
cord-310847-63gh2tg4	430	25	be	be	VB
cord-310847-63gh2tg4	430	26	found	find	VBN
cord-310847-63gh2tg4	430	27	well	well	RB
cord-310847-63gh2tg4	430	28	above	above	IN
cord-310847-63gh2tg4	430	29	the	the	DT
cord-310847-63gh2tg4	430	30	boundary	boundary	NN
cord-310847-63gh2tg4	430	31	separating	separate	VBG
cord-310847-63gh2tg4	430	32	compact	compact	RB
cord-310847-63gh2tg4	430	33	and	and	CC
cord-310847-63gh2tg4	430	34	extended	extended	JJ
cord-310847-63gh2tg4	430	35	disordered	disordered	JJ
cord-310847-63gh2tg4	430	36	proteins	protein	NNS
cord-310847-63gh2tg4	430	37	.	.	.
cord-310847-63gh2tg4	431	1	One	one	CD
cord-310847-63gh2tg4	431	2	of	of	IN
cord-310847-63gh2tg4	431	3	the	the	DT
cord-310847-63gh2tg4	431	4	illustrative	illustrative	JJ
cord-310847-63gh2tg4	431	5	examples	example	NNS
cord-310847-63gh2tg4	431	6	of	of	IN
cord-310847-63gh2tg4	431	7	biologically	biologically	RB
cord-310847-63gh2tg4	431	8	active	active	JJ
cord-310847-63gh2tg4	431	9	EBDs	ebd	NNS
cord-310847-63gh2tg4	431	10	(	(	-LRB-
cord-310847-63gh2tg4	431	11	which	which	WDT
cord-310847-63gh2tg4	431	12	are	be	VBP
cord-310847-63gh2tg4	431	13	not	not	RB
cord-310847-63gh2tg4	431	14	tightly	tightly	RB
cord-310847-63gh2tg4	431	15	folded	fold	VBN
cord-310847-63gh2tg4	431	16	,	,	,
cord-310847-63gh2tg4	431	17	but	but	CC
cord-310847-63gh2tg4	431	18	expected	expect	VBN
cord-310847-63gh2tg4	431	19	to	to	TO
cord-310847-63gh2tg4	431	20	have	have	VB
cord-310847-63gh2tg4	431	21	a	a	DT
cord-310847-63gh2tg4	431	22	very	very	RB
cord-310847-63gh2tg4	431	23	extended	extended	JJ
cord-310847-63gh2tg4	431	24	conformation	conformation	NN
cord-310847-63gh2tg4	431	25	)	)	-RRB-
cord-310847-63gh2tg4	431	26	is	be	VBZ
cord-310847-63gh2tg4	431	27	given	give	VBN
cord-310847-63gh2tg4	431	28	by	by	IN
cord-310847-63gh2tg4	431	29	side	side	NN
cord-310847-63gh2tg4	431	30	-	-	HYPH
cord-310847-63gh2tg4	431	31	arms	arm	NNS
cord-310847-63gh2tg4	431	32	of	of	IN
cord-310847-63gh2tg4	431	33	neurofilament	neurofilament	NN
cord-310847-63gh2tg4	431	34	(	(	-LRB-
cord-310847-63gh2tg4	431	35	NF	NF	NNP
cord-310847-63gh2tg4	431	36	)	)	-RRB-
cord-310847-63gh2tg4	431	37	proteins	protein	NNS
cord-310847-63gh2tg4	431	38	.	.	.
cord-310847-63gh2tg4	432	1	164	164	CD
cord-310847-63gh2tg4	433	1	The	the	DT
cord-310847-63gh2tg4	433	2	side	side	NN
cord-310847-63gh2tg4	433	3	-	-	HYPH
cord-310847-63gh2tg4	433	4	arms	arm	NNS
cord-310847-63gh2tg4	433	5	of	of	IN
cord-310847-63gh2tg4	433	6	the	the	DT
cord-310847-63gh2tg4	433	7	NF	nf	NN
cord-310847-63gh2tg4	433	8	heavy	heavy	JJ
cord-310847-63gh2tg4	433	9	polypeptide	polypeptide	NN
cord-310847-63gh2tg4	433	10	,	,	,
cord-310847-63gh2tg4	433	11	NF	NF	NNP
cord-310847-63gh2tg4	433	12	-	-	HYPH
cord-310847-63gh2tg4	433	13	H	H	NNP
cord-310847-63gh2tg4	433	14	(	(	-LRB-
cord-310847-63gh2tg4	433	15	which	which	WDT
cord-310847-63gh2tg4	433	16	are	be	VBP
cord-310847-63gh2tg4	433	17	~600	~600	NFP
cord-310847-63gh2tg4	433	18	amino	amino	NN
cord-310847-63gh2tg4	433	19	acids	acid	NNS
cord-310847-63gh2tg4	433	20	long	long	JJ
cord-310847-63gh2tg4	433	21	)	)	-RRB-
cord-310847-63gh2tg4	433	22	,	,	,
cord-310847-63gh2tg4	433	23	were	be	VBD
cord-310847-63gh2tg4	433	24	shown	show	VBN
cord-310847-63gh2tg4	433	25	by	by	IN
cord-310847-63gh2tg4	433	26	rotary	rotary	JJ
cord-310847-63gh2tg4	433	27	shadow	shadow	NN
cord-310847-63gh2tg4	433	28	electron	electron	NN
cord-310847-63gh2tg4	433	29	microscopy	microscopy	NN
cord-310847-63gh2tg4	433	30	to	to	TO
cord-310847-63gh2tg4	433	31	be	be	VB
cord-310847-63gh2tg4	433	32	~85	~85	NFP
cord-310847-63gh2tg4	433	33	nm	nm	RB
cord-310847-63gh2tg4	433	34	long	long	RB
cord-310847-63gh2tg4	433	35	.	.	.
cord-310847-63gh2tg4	434	1	Since	since	IN
cord-310847-63gh2tg4	434	2	there	there	EX
cord-310847-63gh2tg4	434	3	was	be	VBD
cord-310847-63gh2tg4	434	4	not	not	RB
cord-310847-63gh2tg4	434	5	enough	enough	JJ
cord-310847-63gh2tg4	434	6	mass	mass	NN
cord-310847-63gh2tg4	434	7	to	to	TO
cord-310847-63gh2tg4	434	8	form	form	VB
cord-310847-63gh2tg4	434	9	a	a	DT
cord-310847-63gh2tg4	434	10	stiff	stiff	JJ
cord-310847-63gh2tg4	434	11	folded	fold	VBN
cord-310847-63gh2tg4	434	12	structure	structure	NN
cord-310847-63gh2tg4	434	13	to	to	TO
cord-310847-63gh2tg4	434	14	occupy	occupy	VB
cord-310847-63gh2tg4	434	15	such	such	PDT
cord-310847-63gh2tg4	434	16	a	a	DT
cord-310847-63gh2tg4	434	17	volume	volume	NN
cord-310847-63gh2tg4	434	18	,	,	,
cord-310847-63gh2tg4	434	19	it	-PRON-	PRP
cord-310847-63gh2tg4	434	20	was	be	VBD
cord-310847-63gh2tg4	434	21	proposed	propose	VBN
cord-310847-63gh2tg4	434	22	that	that	IN
cord-310847-63gh2tg4	434	23	the	the	DT
cord-310847-63gh2tg4	434	24	side	side	NN
cord-310847-63gh2tg4	434	25	-	-	HYPH
cord-310847-63gh2tg4	434	26	arms	arm	NNS
cord-310847-63gh2tg4	434	27	were	be	VBD
cord-310847-63gh2tg4	434	28	not	not	RB
cord-310847-63gh2tg4	434	29	folded	fold	VBN
cord-310847-63gh2tg4	434	30	but	but	CC
cord-310847-63gh2tg4	434	31	were	be	VBD
cord-310847-63gh2tg4	434	32	in	in	IN
cord-310847-63gh2tg4	434	33	constant	constant	JJ
cord-310847-63gh2tg4	434	34	thermal	thermal	JJ
cord-310847-63gh2tg4	434	35	motion	motion	NN
cord-310847-63gh2tg4	434	36	.	.	.
cord-310847-63gh2tg4	435	1	164	164	CD
cord-310847-63gh2tg4	435	2	Analysis	Analysis	NNP
cord-310847-63gh2tg4	435	3	of	of	IN
cord-310847-63gh2tg4	435	4	the	the	DT
cord-310847-63gh2tg4	435	5	amino	amino	NN
cord-310847-63gh2tg4	435	6	acid	acid	NN
cord-310847-63gh2tg4	435	7	sequence	sequence	NN
cord-310847-63gh2tg4	435	8	of	of	IN
cord-310847-63gh2tg4	435	9	the	the	DT
cord-310847-63gh2tg4	435	10	porcine	porcine	JJ
cord-310847-63gh2tg4	435	11	NF	nf	NN
cord-310847-63gh2tg4	435	12	medium	medium	NN
cord-310847-63gh2tg4	435	13	polypeptide	polypeptide	NN
cord-310847-63gh2tg4	435	14	(	(	-LRB-
cord-310847-63gh2tg4	435	15	NF	NF	NNP
cord-310847-63gh2tg4	435	16	-	-	HYPH
cord-310847-63gh2tg4	435	17	M	M	NNP
cord-310847-63gh2tg4	435	18	,	,	,
cord-310847-63gh2tg4	435	19	which	which	WDT
cord-310847-63gh2tg4	435	20	has	have	VBZ
cord-310847-63gh2tg4	435	21	an	an	DT
cord-310847-63gh2tg4	435	22	apparent	apparent	JJ
cord-310847-63gh2tg4	435	23	molecular	molecular	JJ
cord-310847-63gh2tg4	435	24	mass	mass	NN
cord-310847-63gh2tg4	435	25	of	of	IN
cord-310847-63gh2tg4	435	26	160	160	CD
cord-310847-63gh2tg4	435	27	kDa	kDa	NNS
cord-310847-63gh2tg4	435	28	and	and	CC
cord-310847-63gh2tg4	435	29	is	be	VBZ
cord-310847-63gh2tg4	435	30	one	one	CD
cord-310847-63gh2tg4	435	31	of	of	IN
cord-310847-63gh2tg4	435	32	the	the	DT
cord-310847-63gh2tg4	435	33	two	two	CD
cord-310847-63gh2tg4	435	34	high	high	JJ
cord-310847-63gh2tg4	435	35	molecular	molecular	JJ
cord-310847-63gh2tg4	435	36	mass	mass	NN
cord-310847-63gh2tg4	435	37	components	component	NNS
cord-310847-63gh2tg4	435	38	of	of	IN
cord-310847-63gh2tg4	435	39	mammalian	mammalian	JJ
cord-310847-63gh2tg4	435	40	neurofilaments	neurofilament	NNS
cord-310847-63gh2tg4	435	41	)	)	-RRB-
cord-310847-63gh2tg4	435	42	revealed	reveal	VBD
cord-310847-63gh2tg4	435	43	that	that	IN
cord-310847-63gh2tg4	435	44	this	this	DT
cord-310847-63gh2tg4	435	45	protein	protein	NN
cord-310847-63gh2tg4	435	46	has	have	VBZ
cord-310847-63gh2tg4	435	47	several	several	JJ
cord-310847-63gh2tg4	435	48	peculiar	peculiar	JJ
cord-310847-63gh2tg4	435	49	features	feature	NNS
cord-310847-63gh2tg4	435	50	.	.	.
cord-310847-63gh2tg4	436	1	165	165	CD
cord-310847-63gh2tg4	437	1	The	the	DT
cord-310847-63gh2tg4	437	2	N	n	CD
cord-310847-63gh2tg4	437	3	-	-	HYPH
cord-310847-63gh2tg4	437	4	terminal	terminal	NN
cord-310847-63gh2tg4	437	5	436	436	CD
cord-310847-63gh2tg4	437	6	residues	residue	NNS
cord-310847-63gh2tg4	437	7	contain	contain	VBP
cord-310847-63gh2tg4	437	8	a	a	DT
cord-310847-63gh2tg4	437	9	non	non	JJ
cord-310847-63gh2tg4	437	10	-	-	JJ
cord-310847-63gh2tg4	437	11	α	α	JJ
cord-310847-63gh2tg4	437	12	-	-	HYPH
cord-310847-63gh2tg4	437	13	helical	helical	JJ
cord-310847-63gh2tg4	437	14	arginine	arginine	NN
cord-310847-63gh2tg4	437	15	-	-	HYPH
cord-310847-63gh2tg4	437	16	rich	rich	JJ
cord-310847-63gh2tg4	437	17	headpiece	headpiece	NN
cord-310847-63gh2tg4	437	18	(	(	-LRB-
cord-310847-63gh2tg4	437	19	residues	residue	NNS
cord-310847-63gh2tg4	437	20	1	1	CD
cord-310847-63gh2tg4	437	21	-	-	SYM
cord-310847-63gh2tg4	437	22	98	98	CD
cord-310847-63gh2tg4	437	23	)	)	-RRB-
cord-310847-63gh2tg4	437	24	with	with	IN
cord-310847-63gh2tg4	437	25	multiple	multiple	JJ
cord-310847-63gh2tg4	437	26	β	β	NN
cord-310847-63gh2tg4	437	27	-	-	HYPH
cord-310847-63gh2tg4	437	28	turns	turn	NNS
cord-310847-63gh2tg4	437	29	followed	follow	VBN
cord-310847-63gh2tg4	437	30	by	by	IN
cord-310847-63gh2tg4	437	31	a	a	DT
cord-310847-63gh2tg4	437	32	highly	highly	RB
cord-310847-63gh2tg4	437	33	α	α	NN
cord-310847-63gh2tg4	437	34	-	-	HYPH
cord-310847-63gh2tg4	437	35	helical	helical	JJ
cord-310847-63gh2tg4	437	36	rod	rod	NN
cord-310847-63gh2tg4	437	37	domain	domain	NN
cord-310847-63gh2tg4	437	38	that	that	WDT
cord-310847-63gh2tg4	437	39	forms	form	VBZ
cord-310847-63gh2tg4	437	40	double	double	RB
cord-310847-63gh2tg4	437	41	-	-	HYPH
cord-310847-63gh2tg4	437	42	stranded	strand	VBN
cord-310847-63gh2tg4	437	43	coiled	coiled	JJ
cord-310847-63gh2tg4	437	44	-	-	HYPH
cord-310847-63gh2tg4	437	45	coils	coil	NNS
cord-310847-63gh2tg4	437	46	(	(	-LRB-
cord-310847-63gh2tg4	437	47	residues	residue	NNS
cord-310847-63gh2tg4	437	48	99	99	CD
cord-310847-63gh2tg4	437	49	-	-	SYM
cord-310847-63gh2tg4	437	50	412	412	CD
cord-310847-63gh2tg4	437	51	)	)	-RRB-
cord-310847-63gh2tg4	437	52	,	,	,
cord-310847-63gh2tg4	437	53	followed	follow	VBN
cord-310847-63gh2tg4	437	54	by	by	IN
cord-310847-63gh2tg4	437	55	a	a	DT
cord-310847-63gh2tg4	437	56	C	c	NN
cord-310847-63gh2tg4	437	57	-	-	HYPH
cord-310847-63gh2tg4	437	58	terminal	terminal	NN
cord-310847-63gh2tg4	437	59	tailpiece	tailpiece	NN
cord-310847-63gh2tg4	437	60	extension	extension	NN
cord-310847-63gh2tg4	437	61	(	(	-LRB-
cord-310847-63gh2tg4	437	62	approximately	approximately	RB
cord-310847-63gh2tg4	437	63	500	500	CD
cord-310847-63gh2tg4	437	64	residues	residue	NNS
cord-310847-63gh2tg4	437	65	)	)	-RRB-
cord-310847-63gh2tg4	437	66	that	that	WDT
cord-310847-63gh2tg4	437	67	represents	represent	VBZ
cord-310847-63gh2tg4	437	68	an	an	DT
cord-310847-63gh2tg4	437	69	autonomous	autonomous	JJ
cord-310847-63gh2tg4	437	70	domain	domain	NN
cord-310847-63gh2tg4	437	71	of	of	IN
cord-310847-63gh2tg4	437	72	unique	unique	JJ
cord-310847-63gh2tg4	437	73	amino	amino	NN
cord-310847-63gh2tg4	437	74	acid	acid	NN
cord-310847-63gh2tg4	437	75	composition	composition	NN
cord-310847-63gh2tg4	437	76	,	,	,
cord-310847-63gh2tg4	437	77	being	be	VBG
cord-310847-63gh2tg4	437	78	characterized	characterize	VBN
cord-310847-63gh2tg4	437	79	by	by	IN
cord-310847-63gh2tg4	437	80	a	a	DT
cord-310847-63gh2tg4	437	81	high	high	JJ
cord-310847-63gh2tg4	437	82	content	content	NN
cord-310847-63gh2tg4	437	83	of	of	IN
cord-310847-63gh2tg4	437	84	lysines	lysine	NNS
cord-310847-63gh2tg4	437	85	and	and	CC
cord-310847-63gh2tg4	437	86	particularly	particularly	RB
cord-310847-63gh2tg4	437	87	glutamic	glutamic	JJ
cord-310847-63gh2tg4	437	88	acids	acid	NNS
cord-310847-63gh2tg4	437	89	.	.	.
cord-310847-63gh2tg4	438	1	165	165	CD
cord-310847-63gh2tg4	439	1	In	in	IN
cord-310847-63gh2tg4	439	2	human	human	JJ
cord-310847-63gh2tg4	439	3	NF	nf	NN
cord-310847-63gh2tg4	439	4	-	-	HYPH
cord-310847-63gh2tg4	439	5	M	M	NNP
cord-310847-63gh2tg4	439	6	,	,	,
cord-310847-63gh2tg4	439	7	there	there	EX
cord-310847-63gh2tg4	439	8	are	be	VBP
cord-310847-63gh2tg4	439	9	185	185	CD
cord-310847-63gh2tg4	439	10	glutamic	glutamic	NN
cord-310847-63gh2tg4	439	11	acids	acid	NNS
cord-310847-63gh2tg4	439	12	(	(	-LRB-
cord-310847-63gh2tg4	439	13	20.2	20.2	CD
cord-310847-63gh2tg4	439	14	%	%	NN
cord-310847-63gh2tg4	439	15	)	)	-RRB-
cord-310847-63gh2tg4	439	16	,	,	,
cord-310847-63gh2tg4	439	17	most	most	JJS
cord-310847-63gh2tg4	439	18	of	of	IN
cord-310847-63gh2tg4	439	19	which	which	WDT
cord-310847-63gh2tg4	439	20	are	be	VBP
cord-310847-63gh2tg4	439	21	concentrated	concentrate	VBN
cord-310847-63gh2tg4	439	22	within	within	IN
cord-310847-63gh2tg4	439	23	the	the	DT
cord-310847-63gh2tg4	439	24	C	c	NN
cord-310847-63gh2tg4	439	25	-	-	HYPH
cord-310847-63gh2tg4	439	26	terminal	terminal	NN
cord-310847-63gh2tg4	439	27	tail	tail	NN
cord-310847-63gh2tg4	439	28	,	,	,
cord-310847-63gh2tg4	439	29	where	where	WRB
cord-310847-63gh2tg4	439	30	glutamate	glutamate	NN
cord-310847-63gh2tg4	439	31	accounts	account	VBZ
cord-310847-63gh2tg4	439	32	for	for	IN
cord-310847-63gh2tg4	439	33	26.4	26.4	CD
cord-310847-63gh2tg4	439	34	%	%	NN
cord-310847-63gh2tg4	439	35	(	(	-LRB-
cord-310847-63gh2tg4	439	36	133	133	CD
cord-310847-63gh2tg4	439	37	out	out	IN
cord-310847-63gh2tg4	439	38	of	of	IN
cord-310847-63gh2tg4	439	39	504	504	CD
cord-310847-63gh2tg4	439	40	residues	residue	NNS
cord-310847-63gh2tg4	439	41	)	)	-RRB-
cord-310847-63gh2tg4	439	42	.	.	.
cord-310847-63gh2tg4	440	1	Similarly	similarly	RB
cord-310847-63gh2tg4	440	2	,	,	,
cord-310847-63gh2tg4	440	3	human	human	JJ
cord-310847-63gh2tg4	440	4	NF	nf	NN
cord-310847-63gh2tg4	440	5	-	-	HYPH
cord-310847-63gh2tg4	440	6	H	H	NNP
cord-310847-63gh2tg4	440	7	(	(	-LRB-
cord-310847-63gh2tg4	440	8	a	a	DT
cord-310847-63gh2tg4	440	9	polypeptide	polypeptide	NN
cord-310847-63gh2tg4	440	10	comprising	comprise	VBG
cord-310847-63gh2tg4	440	11	1,026	1,026	CD
cord-310847-63gh2tg4	440	12	residues	residue	NNS
cord-310847-63gh2tg4	440	13	)	)	-RRB-
cord-310847-63gh2tg4	440	14	has	have	VBZ
cord-310847-63gh2tg4	440	15	189	189	CD
cord-310847-63gh2tg4	440	16	glutamic	glutamic	NN
cord-310847-63gh2tg4	440	17	acids	acid	NNS
cord-310847-63gh2tg4	440	18	,	,	,
cord-310847-63gh2tg4	440	19	143	143	CD
cord-310847-63gh2tg4	440	20	of	of	IN
cord-310847-63gh2tg4	440	21	which	which	WDT
cord-310847-63gh2tg4	440	22	are	be	VBP
cord-310847-63gh2tg4	440	23	found	find	VBN
cord-310847-63gh2tg4	440	24	in	in	IN
cord-310847-63gh2tg4	440	25	the	the	DT
cord-310847-63gh2tg4	440	26	613	613	CD
cord-310847-63gh2tg4	440	27	residues	residue	NNS
cord-310847-63gh2tg4	440	28	-	-	HYPH
cord-310847-63gh2tg4	440	29	long	long	JJ
cord-310847-63gh2tg4	440	30	C	c	NN
cord-310847-63gh2tg4	440	31	-	-	HYPH
cord-310847-63gh2tg4	440	32	terminal	terminal	NN
cord-310847-63gh2tg4	440	33	tail	tail	NN
cord-310847-63gh2tg4	440	34	of	of	IN
cord-310847-63gh2tg4	440	35	this	this	DT
cord-310847-63gh2tg4	440	36	protein	protein	NN
cord-310847-63gh2tg4	440	37	,	,	,
cord-310847-63gh2tg4	440	38	whereas	whereas	IN
cord-310847-63gh2tg4	440	39	in	in	IN
cord-310847-63gh2tg4	440	40	the	the	DT
cord-310847-63gh2tg4	440	41	human	human	JJ
cord-310847-63gh2tg4	440	42	NF	nf	NN
cord-310847-63gh2tg4	440	43	-	-	HYPH
cord-310847-63gh2tg4	440	44	L	L	NNP
cord-310847-63gh2tg4	440	45	(	(	-LRB-
cord-310847-63gh2tg4	440	46	NF	NF	NNP
cord-310847-63gh2tg4	440	47	light	light	JJ
cord-310847-63gh2tg4	440	48	polypeptide	polypeptide	NN
cord-310847-63gh2tg4	440	49	which	which	WDT
cord-310847-63gh2tg4	440	50	has	have	VBZ
cord-310847-63gh2tg4	440	51	543	543	CD
cord-310847-63gh2tg4	440	52	residues	residue	NNS
cord-310847-63gh2tg4	440	53	)	)	-RRB-
cord-310847-63gh2tg4	440	54	,	,	,
cord-310847-63gh2tg4	440	55	there	there	EX
cord-310847-63gh2tg4	440	56	are	be	VBP
cord-310847-63gh2tg4	440	57	99	99	CD
cord-310847-63gh2tg4	440	58	glutamic	glutamic	NN
cord-310847-63gh2tg4	440	59	acids	acid	NNS
cord-310847-63gh2tg4	440	60	,	,	,
cord-310847-63gh2tg4	440	61	with	with	IN
cord-310847-63gh2tg4	440	62	almost	almost	RB
cord-310847-63gh2tg4	440	63	half	half	NN
cord-310847-63gh2tg4	440	64	of	of	IN
cord-310847-63gh2tg4	440	65	which	which	WDT
cord-310847-63gh2tg4	440	66	(	(	-LRB-
cord-310847-63gh2tg4	440	67	46	46	CD
cord-310847-63gh2tg4	440	68	)	)	-RRB-
cord-310847-63gh2tg4	440	69	being	be	VBG
cord-310847-63gh2tg4	440	70	located	locate	VBN
cord-310847-63gh2tg4	440	71	within	within	IN
cord-310847-63gh2tg4	440	72	the	the	DT
cord-310847-63gh2tg4	440	73	acidic	acidic	JJ
cord-310847-63gh2tg4	440	74	C	c	NN
cord-310847-63gh2tg4	440	75	-	-	HYPH
cord-310847-63gh2tg4	440	76	terminal	terminal	NN
cord-310847-63gh2tg4	440	77	subdomain	subdomain	NN
cord-310847-63gh2tg4	440	78	(	(	-LRB-
cord-310847-63gh2tg4	440	79	the	the	DT
cord-310847-63gh2tg4	440	80	last	last	JJ
cord-310847-63gh2tg4	440	81	100	100	CD
cord-310847-63gh2tg4	440	82	residues	residue	NNS
cord-310847-63gh2tg4	440	83	of	of	IN
cord-310847-63gh2tg4	440	84	the	the	DT
cord-310847-63gh2tg4	440	85	protein	protein	NN
cord-310847-63gh2tg4	440	86	)	)	-RRB-
cord-310847-63gh2tg4	440	87	.	.	.
cord-310847-63gh2tg4	441	1	In	in	IN
cord-310847-63gh2tg4	441	2	addition	addition	NN
cord-310847-63gh2tg4	441	3	to	to	IN
cord-310847-63gh2tg4	441	4	neurofilament	neurofilament	NNP
cord-310847-63gh2tg4	441	5	polypeptides	polypeptide	NNS
cord-310847-63gh2tg4	441	6	,	,	,
cord-310847-63gh2tg4	441	7	EBDs	ebd	NNS
cord-310847-63gh2tg4	441	8	were	be	VBD
cord-310847-63gh2tg4	441	9	found	find	VBN
cord-310847-63gh2tg4	441	10	in	in	IN
cord-310847-63gh2tg4	441	11	microtubuleassociated	microtubuleassociated	JJ
cord-310847-63gh2tg4	441	12	protein	protein	NN
cord-310847-63gh2tg4	441	13	2	2	CD
cord-310847-63gh2tg4	441	14	(	(	-LRB-
cord-310847-63gh2tg4	441	15	MAP2	MAP2	NNP
cord-310847-63gh2tg4	441	16	)	)	-RRB-
cord-310847-63gh2tg4	441	17	166	166	CD
cord-310847-63gh2tg4	441	18	and	and	CC
cord-310847-63gh2tg4	441	19	NuMa	NuMa	NNP
cord-310847-63gh2tg4	441	20	.	.	.
cord-310847-63gh2tg4	442	1	167	167	CD
cord-310847-63gh2tg4	442	2	Analysis	Analysis	NNP
cord-310847-63gh2tg4	442	3	of	of	IN
cord-310847-63gh2tg4	442	4	the	the	DT
cord-310847-63gh2tg4	442	5	amino	amino	NN
cord-310847-63gh2tg4	442	6	acid	acid	NN
cord-310847-63gh2tg4	442	7	compositions	composition	NNS
cord-310847-63gh2tg4	442	8	of	of	IN
cord-310847-63gh2tg4	442	9	these	these	DT
cord-310847-63gh2tg4	442	10	proteins	protein	NNS
cord-310847-63gh2tg4	442	11	revealed	reveal	VBD
cord-310847-63gh2tg4	442	12	that	that	IN
cord-310847-63gh2tg4	442	13	they	-PRON-	PRP
cord-310847-63gh2tg4	442	14	follow	follow	VBP
cord-310847-63gh2tg4	442	15	the	the	DT
cord-310847-63gh2tg4	442	16	trend	trend	NN
cord-310847-63gh2tg4	442	17	established	establish	VBN
cord-310847-63gh2tg4	442	18	by	by	IN
cord-310847-63gh2tg4	442	19	NFs	nfs	NN
cord-310847-63gh2tg4	442	20	and	and	CC
cord-310847-63gh2tg4	442	21	contain	contain	VBP
cord-310847-63gh2tg4	442	22	significant	significant	JJ
cord-310847-63gh2tg4	442	23	amount	amount	NN
cord-310847-63gh2tg4	442	24	of	of	IN
cord-310847-63gh2tg4	442	25	glutamic	glutamic	NN
cord-310847-63gh2tg4	442	26	acid	acid	NN
cord-310847-63gh2tg4	442	27	residues	residue	NNS
cord-310847-63gh2tg4	442	28	(	(	-LRB-
cord-310847-63gh2tg4	442	29	220	220	CD
cord-310847-63gh2tg4	442	30	out	out	IN
cord-310847-63gh2tg4	442	31	of	of	IN
cord-310847-63gh2tg4	442	32	1,827	1,827	CD
cord-310847-63gh2tg4	442	33	residues	residue	NNS
cord-310847-63gh2tg4	442	34	in	in	IN
cord-310847-63gh2tg4	442	35	human	human	JJ
cord-310847-63gh2tg4	442	36	MAP2	map2	CD
cord-310847-63gh2tg4	442	37	are	be	VBP
cord-310847-63gh2tg4	442	38	glutamates	glutamate	NNS
cord-310847-63gh2tg4	442	39	and	and	CC
cord-310847-63gh2tg4	442	40	there	there	EX
cord-310847-63gh2tg4	442	41	are	be	VBP
cord-310847-63gh2tg4	442	42	291	291	CD
cord-310847-63gh2tg4	442	43	glutamic	glutamic	NN
cord-310847-63gh2tg4	442	44	acids	acid	NNS
cord-310847-63gh2tg4	442	45	in	in	IN
cord-310847-63gh2tg4	442	46	the	the	DT
cord-310847-63gh2tg4	442	47	2,115	2,115	CD
cord-310847-63gh2tg4	442	48	residues	residue	NNS
cord-310847-63gh2tg4	442	49	-	-	HYPH
cord-310847-63gh2tg4	442	50	long	long	JJ
cord-310847-63gh2tg4	442	51	human	human	JJ
cord-310847-63gh2tg4	442	52	NuMa	NuMa	NNP
cord-310847-63gh2tg4	442	53	)	)	-RRB-
cord-310847-63gh2tg4	442	54	.	.	.
cord-310847-63gh2tg4	443	1	natural	natural	JJ
cord-310847-63gh2tg4	443	2	biopolymer	biopolymer	NNP
cord-310847-63gh2tg4	443	3	is	be	VBZ
cord-310847-63gh2tg4	443	4	nontoxic	nontoxic	JJ
cord-310847-63gh2tg4	443	5	,	,	,
cord-310847-63gh2tg4	443	6	biocompatible	biocompatible	JJ
cord-310847-63gh2tg4	443	7	and	and	CC
cord-310847-63gh2tg4	443	8	nonimmunogenic	nonimmunogenic	NNP
cord-310847-63gh2tg4	443	9	.	.	.
cord-310847-63gh2tg4	444	1	It	-PRON-	PRP
cord-310847-63gh2tg4	444	2	can	can	MD
cord-310847-63gh2tg4	444	3	be	be	VB
cord-310847-63gh2tg4	444	4	produced	produce	VBN
cord-310847-63gh2tg4	444	5	by	by	IN
cord-310847-63gh2tg4	444	6	various	various	JJ
cord-310847-63gh2tg4	444	7	bacterial	bacterial	JJ
cord-310847-63gh2tg4	444	8	strains	strain	NNS
cord-310847-63gh2tg4	444	9	in	in	IN
cord-310847-63gh2tg4	444	10	a	a	DT
cord-310847-63gh2tg4	444	11	controllable	controllable	JJ
cord-310847-63gh2tg4	444	12	way	way	NN
cord-310847-63gh2tg4	444	13	.	.	.
cord-310847-63gh2tg4	445	1	152	152	CD
cord-310847-63gh2tg4	446	1	As	as	IN
cord-310847-63gh2tg4	446	2	a	a	DT
cord-310847-63gh2tg4	446	3	result	result	NN
cord-310847-63gh2tg4	446	4	,	,	,
cord-310847-63gh2tg4	446	5	PGA	PGA	NNP
cord-310847-63gh2tg4	446	6	is	be	VBZ
cord-310847-63gh2tg4	446	7	commonly	commonly	RB
cord-310847-63gh2tg4	446	8	used	use	VBN
cord-310847-63gh2tg4	446	9	in	in	IN
cord-310847-63gh2tg4	446	10	cosmetics/	cosmetics/	``
cord-310847-63gh2tg4	446	11	skin	skin	NN
cord-310847-63gh2tg4	446	12	care	care	NN
cord-310847-63gh2tg4	446	13	,	,	,
cord-310847-63gh2tg4	446	14	bone	bone	NN
cord-310847-63gh2tg4	446	15	care	care	NN
cord-310847-63gh2tg4	446	16	,	,	,
cord-310847-63gh2tg4	446	17	nanoparticle	nanoparticle	NN
cord-310847-63gh2tg4	446	18	for	for	IN
cord-310847-63gh2tg4	446	19	drug	drug	NN
cord-310847-63gh2tg4	446	20	delivery	delivery	NN
cord-310847-63gh2tg4	446	21	system	system	NN
cord-310847-63gh2tg4	446	22	,	,	,
cord-310847-63gh2tg4	446	23	hydrogel	hydrogel	NN
cord-310847-63gh2tg4	446	24	,	,	,
cord-310847-63gh2tg4	446	25	etc	etc	FW
cord-310847-63gh2tg4	446	26	.	.	.
cord-310847-63gh2tg4	447	1	154	154	CD
cord-310847-63gh2tg4	448	1	For	for	IN
cord-310847-63gh2tg4	448	2	example	example	NN
cord-310847-63gh2tg4	448	3	,	,	,
cord-310847-63gh2tg4	448	4	the	the	DT
cord-310847-63gh2tg4	448	5	PGA	PGA	NNP
cord-310847-63gh2tg4	448	6	-	-	HYPH
cord-310847-63gh2tg4	448	7	based	base	VBN
cord-310847-63gh2tg4	448	8	Medusa	Medusa	NNP
cord-310847-63gh2tg4	448	9	system	system	NN
cord-310847-63gh2tg4	448	10	has	have	VBZ
cord-310847-63gh2tg4	448	11	been	be	VBN
cord-310847-63gh2tg4	448	12	recently	recently	RB
cord-310847-63gh2tg4	448	13	developed	develop	VBN
cord-310847-63gh2tg4	448	14	for	for	IN
cord-310847-63gh2tg4	448	15	slow	slow	JJ
cord-310847-63gh2tg4	448	16	release	release	NN
cord-310847-63gh2tg4	448	17	of	of	IN
cord-310847-63gh2tg4	448	18	therapeutic	therapeutic	JJ
cord-310847-63gh2tg4	448	19	proteins	protein	NNS
cord-310847-63gh2tg4	448	20	and	and	CC
cord-310847-63gh2tg4	448	21	peptides	peptide	NNS
cord-310847-63gh2tg4	448	22	.	.	.
cord-310847-63gh2tg4	449	1	155	155	CD
cord-310847-63gh2tg4	450	1	Here	here	RB
cord-310847-63gh2tg4	450	2	,	,	,
cord-310847-63gh2tg4	450	3	a	a	DT
cord-310847-63gh2tg4	450	4	poly	poly	JJ
cord-310847-63gh2tg4	450	5	L	l	NN
cord-310847-63gh2tg4	450	6	-	-	HYPH
cord-310847-63gh2tg4	450	7	glutamate	glutamate	NN
cord-310847-63gh2tg4	450	8	backbone	backbone	NN
cord-310847-63gh2tg4	450	9	is	be	VBZ
cord-310847-63gh2tg4	450	10	grafted	graft	VBN
cord-310847-63gh2tg4	450	11	with	with	IN
cord-310847-63gh2tg4	450	12	hydrophobic	hydrophobic	JJ
cord-310847-63gh2tg4	450	13	α	α	NN
cord-310847-63gh2tg4	450	14	-	-	HYPH
cord-310847-63gh2tg4	450	15	tocopherol	tocopherol	NN
cord-310847-63gh2tg4	450	16	molecules	molecule	NNS
cord-310847-63gh2tg4	450	17	,	,	,
cord-310847-63gh2tg4	450	18	creating	create	VBG
cord-310847-63gh2tg4	450	19	a	a	DT
cord-310847-63gh2tg4	450	20	colloidal	colloidal	JJ
cord-310847-63gh2tg4	450	21	suspension	suspension	NN
cord-310847-63gh2tg4	450	22	of	of	IN
cord-310847-63gh2tg4	450	23	nanoparticles	nanoparticle	NNS
cord-310847-63gh2tg4	450	24	in	in	IN
cord-310847-63gh2tg4	450	25	water	water	NN
cord-310847-63gh2tg4	450	26	that	that	WDT
cord-310847-63gh2tg4	450	27	contain	contain	VBP
cord-310847-63gh2tg4	450	28	hydrophobic	hydrophobic	JJ
cord-310847-63gh2tg4	450	29	nanodomains	nanodomain	NNS
cord-310847-63gh2tg4	450	30	suitable	suitable	JJ
cord-310847-63gh2tg4	450	31	for	for	IN
cord-310847-63gh2tg4	450	32	the	the	DT
cord-310847-63gh2tg4	450	33	reversible	reversible	JJ
cord-310847-63gh2tg4	450	34	binding	binding	NN
cord-310847-63gh2tg4	450	35	of	of	IN
cord-310847-63gh2tg4	450	36	various	various	JJ
cord-310847-63gh2tg4	450	37	drug	drug	NN
cord-310847-63gh2tg4	450	38	molecules	molecule	NNS
cord-310847-63gh2tg4	450	39	.	.	.
cord-310847-63gh2tg4	451	1	155	155	CD
cord-310847-63gh2tg4	452	1	The	the	DT
cord-310847-63gh2tg4	452	2	potential	potential	JJ
cord-310847-63gh2tg4	452	3	multifarious	multifarious	JJ
cord-310847-63gh2tg4	452	4	applications	application	NNS
cord-310847-63gh2tg4	452	5	of	of	IN
cord-310847-63gh2tg4	452	6	PGA	PGA	NNP
cord-310847-63gh2tg4	452	7	in	in	IN
cord-310847-63gh2tg4	452	8	the	the	DT
cord-310847-63gh2tg4	452	9	areas	area	NNS
cord-310847-63gh2tg4	452	10	of	of	IN
cord-310847-63gh2tg4	452	11	biomedical	biomedical	JJ
cord-310847-63gh2tg4	452	12	materials	material	NNS
cord-310847-63gh2tg4	452	13	,	,	,
cord-310847-63gh2tg4	452	14	drug	drug	NN
cord-310847-63gh2tg4	452	15	delivery	delivery	NN
cord-310847-63gh2tg4	452	16	carriers	carrier	NNS
cord-310847-63gh2tg4	452	17	,	,	,
cord-310847-63gh2tg4	452	18	and	and	CC
cord-310847-63gh2tg4	452	19	biological	biological	JJ
cord-310847-63gh2tg4	452	20	adhesives	adhesive	NNS
cord-310847-63gh2tg4	452	21	have	have	VBP
cord-310847-63gh2tg4	452	22	been	be	VBN
cord-310847-63gh2tg4	452	23	studied	study	VBN
cord-310847-63gh2tg4	452	24	extensively	extensively	RB
cord-310847-63gh2tg4	452	25	.	.	.
cord-310847-63gh2tg4	453	1	156	156	CD
cord-310847-63gh2tg4	454	1	In	in	IN
cord-310847-63gh2tg4	454	2	general	general	JJ
cord-310847-63gh2tg4	454	3	,	,	,
cord-310847-63gh2tg4	454	4	γ	γ	NNP
cord-310847-63gh2tg4	454	5	-	-	HYPH
cord-310847-63gh2tg4	454	6	PGA	PGA	NNP
cord-310847-63gh2tg4	454	7	is	be	VBZ
cord-310847-63gh2tg4	454	8	recognized	recognize	VBN
cord-310847-63gh2tg4	454	9	now	now	RB
cord-310847-63gh2tg4	454	10	as	as	IN
cord-310847-63gh2tg4	454	11	an	an	DT
cord-310847-63gh2tg4	454	12	important	important	JJ
cord-310847-63gh2tg4	454	13	biomaterial	biomaterial	NN
cord-310847-63gh2tg4	454	14	in	in	IN
cord-310847-63gh2tg4	454	15	drug	drug	NN
cord-310847-63gh2tg4	454	16	delivery	delivery	NN
cord-310847-63gh2tg4	454	17	applications	application	NNS
cord-310847-63gh2tg4	454	18	,	,	,
cord-310847-63gh2tg4	454	19	with	with	IN
cord-310847-63gh2tg4	454	20	γ	γ	NNP
cord-310847-63gh2tg4	454	21	-	-	HYPH
cord-310847-63gh2tg4	454	22	PGA	PGA	NNP
cord-310847-63gh2tg4	454	23	-	-	HYPH
cord-310847-63gh2tg4	454	24	based	base	VBN
cord-310847-63gh2tg4	454	25	nanoparticles	nanoparticle	NNS
cord-310847-63gh2tg4	454	26	being	be	VBG
cord-310847-63gh2tg4	454	27	considered	consider	VBN
cord-310847-63gh2tg4	454	28	as	as	IN
cord-310847-63gh2tg4	454	29	promising	promising	JJ
cord-310847-63gh2tg4	454	30	delivery	delivery	NN
cord-310847-63gh2tg4	454	31	carriers	carrier	NNS
cord-310847-63gh2tg4	454	32	for	for	IN
cord-310847-63gh2tg4	454	33	anticancer	anticancer	JJ
cord-310847-63gh2tg4	454	34	therapeutics	therapeutic	NNS
cord-310847-63gh2tg4	454	35	.	.	.
cord-310847-63gh2tg4	455	1	157	157	CD
cord-310847-63gh2tg4	456	1	Recently	recently	RB
cord-310847-63gh2tg4	456	2	,	,	,
cord-310847-63gh2tg4	456	3	a	a	DT
cord-310847-63gh2tg4	456	4	high	high	JJ
cord-310847-63gh2tg4	456	5	molecular	molecular	JJ
cord-310847-63gh2tg4	456	6	weight	weight	NN
cord-310847-63gh2tg4	456	7	γ	γ	NNP
cord-310847-63gh2tg4	456	8	-	-	:
cord-310847-63gh2tg4	456	9	PGA	PGA	NNP
cord-310847-63gh2tg4	456	10	was	be	VBD
cord-310847-63gh2tg4	456	11	shown	show	VBN
cord-310847-63gh2tg4	456	12	to	to	TO
cord-310847-63gh2tg4	456	13	be	be	VB
cord-310847-63gh2tg4	456	14	used	use	VBN
cord-310847-63gh2tg4	456	15	as	as	IN
cord-310847-63gh2tg4	456	16	an	an	DT
cord-310847-63gh2tg4	456	17	immune	immune	NN
cord-310847-63gh2tg4	456	18	-	-	HYPH
cord-310847-63gh2tg4	456	19	stimulating	stimulate	VBG
cord-310847-63gh2tg4	456	20	agent	agent	NN
cord-310847-63gh2tg4	456	21	.	.	.
cord-310847-63gh2tg4	457	1	154	154	CD
cord-310847-63gh2tg4	458	1	Finally	finally	RB
cord-310847-63gh2tg4	458	2	,	,	,
cord-310847-63gh2tg4	458	3	conjugation	conjugation	NN
cord-310847-63gh2tg4	458	4	of	of	IN
cord-310847-63gh2tg4	458	5	paclitaxel	paclitaxel	NN
cord-310847-63gh2tg4	458	6	,	,	,
cord-310847-63gh2tg4	458	7	a	a	DT
cord-310847-63gh2tg4	458	8	widely	widely	RB
cord-310847-63gh2tg4	458	9	used	use	VBN
cord-310847-63gh2tg4	458	10	chemotherapeutic	chemotherapeutic	JJ
cord-310847-63gh2tg4	458	11	agent	agent	NN
cord-310847-63gh2tg4	458	12	whose	whose	WP$
cord-310847-63gh2tg4	458	13	therapeutic	therapeutic	JJ
cord-310847-63gh2tg4	458	14	index	index	NN
cord-310847-63gh2tg4	458	15	is	be	VBZ
cord-310847-63gh2tg4	458	16	limited	limit	VBN
cord-310847-63gh2tg4	458	17	by	by	IN
cord-310847-63gh2tg4	458	18	low	low	JJ
cord-310847-63gh2tg4	458	19	tumor	tumor	NN
cord-310847-63gh2tg4	458	20	exposure	exposure	NN
cord-310847-63gh2tg4	458	21	and	and	CC
cord-310847-63gh2tg4	458	22	high	high	JJ
cord-310847-63gh2tg4	458	23	systemic	systemic	JJ
cord-310847-63gh2tg4	458	24	exposure	exposure	NN
cord-310847-63gh2tg4	458	25	,	,	,
cord-310847-63gh2tg4	458	26	with	with	IN
cord-310847-63gh2tg4	459	1	biodegradable	biodegradable	JJ
cord-310847-63gh2tg4	459	2	poly	poly	JJ
cord-310847-63gh2tg4	459	3	-	-	HYPH
cord-310847-63gh2tg4	459	4	lglutamic	lglutamic	JJ
cord-310847-63gh2tg4	459	5	acid	acid	NN
cord-310847-63gh2tg4	459	6	generates	generate	VBZ
cord-310847-63gh2tg4	459	7	paclitaxel	paclitaxel	NNP
cord-310847-63gh2tg4	459	8	poliglumex	poliglumex	NNP
cord-310847-63gh2tg4	459	9	(	(	-LRB-
cord-310847-63gh2tg4	459	10	PPX	PPX	NNP
cord-310847-63gh2tg4	459	11	,	,	,
cord-310847-63gh2tg4	459	12	CT-2103	CT-2103	NNP
cord-310847-63gh2tg4	459	13	)	)	-RRB-
cord-310847-63gh2tg4	459	14	.	.	.
cord-310847-63gh2tg4	460	1	158	158	CD
cord-310847-63gh2tg4	461	1	This	this	DT
cord-310847-63gh2tg4	461	2	macromolecular	macromolecular	JJ
cord-310847-63gh2tg4	461	3	drug	drug	NN
cord-310847-63gh2tg4	461	4	conjugate	conjugate	NN
cord-310847-63gh2tg4	461	5	enhances	enhance	VBZ
cord-310847-63gh2tg4	461	6	tumor	tumor	NN
cord-310847-63gh2tg4	461	7	exposure	exposure	NN
cord-310847-63gh2tg4	461	8	to	to	IN
cord-310847-63gh2tg4	461	9	the	the	DT
cord-310847-63gh2tg4	461	10	drug	drug	NN
cord-310847-63gh2tg4	461	11	,	,	,
cord-310847-63gh2tg4	461	12	since	since	IN
cord-310847-63gh2tg4	461	13	the	the	DT
cord-310847-63gh2tg4	461	14	release	release	NN
cord-310847-63gh2tg4	461	15	of	of	IN
cord-310847-63gh2tg4	461	16	paclitaxel	paclitaxel	NN
cord-310847-63gh2tg4	461	17	from	from	IN
cord-310847-63gh2tg4	461	18	the	the	DT
cord-310847-63gh2tg4	461	19	polymeric	polymeric	JJ
cord-310847-63gh2tg4	461	20	backbone	backbone	NN
cord-310847-63gh2tg4	461	21	was	be	VBD
cord-310847-63gh2tg4	461	22	shown	show	VBN
cord-310847-63gh2tg4	461	23	to	to	TO
cord-310847-63gh2tg4	461	24	be	be	VB
cord-310847-63gh2tg4	461	25	dependent	dependent	JJ
cord-310847-63gh2tg4	461	26	on	on	IN
cord-310847-63gh2tg4	461	27	the	the	DT
cord-310847-63gh2tg4	461	28	PPX	PPX	NNP
cord-310847-63gh2tg4	461	29	degradation	degradation	NN
cord-310847-63gh2tg4	461	30	by	by	IN
cord-310847-63gh2tg4	461	31	the	the	DT
cord-310847-63gh2tg4	461	32	lysosomal	lysosomal	JJ
cord-310847-63gh2tg4	461	33	protease	protease	NN
cord-310847-63gh2tg4	461	34	cathepsin	cathepsin	NN
cord-310847-63gh2tg4	461	35	B	b	NN
cord-310847-63gh2tg4	461	36	,	,	,
cord-310847-63gh2tg4	461	37	which	which	WDT
cord-310847-63gh2tg4	461	38	is	be	VBZ
cord-310847-63gh2tg4	461	39	upregulated	upregulate	VBN
cord-310847-63gh2tg4	461	40	in	in	IN
cord-310847-63gh2tg4	461	41	many	many	JJ
cord-310847-63gh2tg4	461	42	tumor	tumor	NN
cord-310847-63gh2tg4	461	43	types	type	NNS
cord-310847-63gh2tg4	461	44	.	.	.
cord-310847-63gh2tg4	462	1	158	158	CD
cord-310847-63gh2tg4	462	2	Glutamic	glutamic	NN
cord-310847-63gh2tg4	462	3	acid	acid	NN
cord-310847-63gh2tg4	462	4	as	as	IN
cord-310847-63gh2tg4	462	5	a	a	DT
cord-310847-63gh2tg4	462	6	part	part	NN
cord-310847-63gh2tg4	462	7	of	of	IN
cord-310847-63gh2tg4	462	8	the	the	DT
cord-310847-63gh2tg4	462	9	protein	protein	NN
cord-310847-63gh2tg4	462	10	degradation	degradation	NN
cord-310847-63gh2tg4	462	11	targeting	target	VBG
cord-310847-63gh2tg4	462	12	signals	signal	NNS
cord-310847-63gh2tg4	462	13	,	,	,
cord-310847-63gh2tg4	462	14	PEST	pest	NN
cord-310847-63gh2tg4	462	15	motifs	motif	NNS
cord-310847-63gh2tg4	462	16	.	.	.
cord-310847-63gh2tg4	463	1	PEST	PEST	NNP
cord-310847-63gh2tg4	463	2	sequences	sequence	NNS
cord-310847-63gh2tg4	463	3	(	(	-LRB-
cord-310847-63gh2tg4	463	4	i.e.	i.e.	FW
cord-310847-63gh2tg4	463	5	,	,	,
cord-310847-63gh2tg4	463	6	sequences	sequence	NNS
cord-310847-63gh2tg4	463	7	enriched	enrich	VBN
cord-310847-63gh2tg4	463	8	in	in	IN
cord-310847-63gh2tg4	463	9	proline	proline	NN
cord-310847-63gh2tg4	463	10	(	(	-LRB-
cord-310847-63gh2tg4	463	11	P	p	NN
cord-310847-63gh2tg4	463	12	)	)	-RRB-
cord-310847-63gh2tg4	463	13	,	,	,
cord-310847-63gh2tg4	463	14	glutamic	glutamic	NN
cord-310847-63gh2tg4	463	15	acid	acid	NN
cord-310847-63gh2tg4	463	16	(	(	-LRB-
cord-310847-63gh2tg4	463	17	E	E	NNP
cord-310847-63gh2tg4	463	18	)	)	-RRB-
cord-310847-63gh2tg4	463	19	,	,	,
cord-310847-63gh2tg4	463	20	serine	serine	NN
cord-310847-63gh2tg4	463	21	(	(	-LRB-
cord-310847-63gh2tg4	463	22	S	S	NNP
cord-310847-63gh2tg4	463	23	)	)	-RRB-
cord-310847-63gh2tg4	463	24	and	and	CC
cord-310847-63gh2tg4	463	25	threonine	threonine	NN
cord-310847-63gh2tg4	463	26	(	(	-LRB-
cord-310847-63gh2tg4	463	27	T	T	NNP
cord-310847-63gh2tg4	463	28	)	)	-RRB-
cord-310847-63gh2tg4	463	29	)	)	-RRB-
cord-310847-63gh2tg4	463	30	are	be	VBP
cord-310847-63gh2tg4	463	31	known	know	VBN
cord-310847-63gh2tg4	463	32	to	to	TO
cord-310847-63gh2tg4	463	33	serve	serve	VB
cord-310847-63gh2tg4	463	34	as	as	IN
cord-310847-63gh2tg4	463	35	specific	specific	JJ
cord-310847-63gh2tg4	463	36	degradation	degradation	NN
cord-310847-63gh2tg4	463	37	signals	signal	NNS
cord-310847-63gh2tg4	463	38	.	.	.
cord-310847-63gh2tg4	464	1	[	[	-LRB-
cord-310847-63gh2tg4	464	2	159	159	CD
cord-310847-63gh2tg4	464	3	]	]	-RRB-
cord-310847-63gh2tg4	464	4	[	[	-LRB-
cord-310847-63gh2tg4	464	5	160	160	CD
cord-310847-63gh2tg4	464	6	]	]	-RRB-
cord-310847-63gh2tg4	464	7	[	[	-LRB-
cord-310847-63gh2tg4	464	8	161	161	CD
cord-310847-63gh2tg4	464	9	]	]	-RRB-
cord-310847-63gh2tg4	465	1	[	[	-LRB-
cord-310847-63gh2tg4	465	2	162	162	CD
cord-310847-63gh2tg4	465	3	]	]	-RRB-
cord-310847-63gh2tg4	466	1	These	these	DT
cord-310847-63gh2tg4	466	2	degradation	degradation	NN
cord-310847-63gh2tg4	466	3	signals	signal	NNS
cord-310847-63gh2tg4	466	4	define	define	VBP
cord-310847-63gh2tg4	466	5	cellular	cellular	JJ
cord-310847-63gh2tg4	466	6	instability	instability	NN
cord-310847-63gh2tg4	466	7	of	of	IN
cord-310847-63gh2tg4	466	8	many	many	JJ
cord-310847-63gh2tg4	466	9	proteins	protein	NNS
cord-310847-63gh2tg4	466	10	and	and	CC
cord-310847-63gh2tg4	466	11	direct	direct	VB
cord-310847-63gh2tg4	466	12	them	-PRON-	PRP
cord-310847-63gh2tg4	466	13	either	either	CC
cord-310847-63gh2tg4	466	14	to	to	IN
cord-310847-63gh2tg4	466	15	the	the	DT
cord-310847-63gh2tg4	466	16	ubiquitin	ubiquitin	NN
cord-310847-63gh2tg4	466	17	-	-	HYPH
cord-310847-63gh2tg4	466	18	proteasome	proteasome	VBN
cord-310847-63gh2tg4	466	19	degradation	degradation	NN
cord-310847-63gh2tg4	466	20	or	or	CC
cord-310847-63gh2tg4	466	21	to	to	IN
cord-310847-63gh2tg4	466	22	the	the	DT
cord-310847-63gh2tg4	466	23	calpain	calpain	NN
cord-310847-63gh2tg4	466	24	cleavage	cleavage	NN
cord-310847-63gh2tg4	466	25	.	.	.
cord-310847-63gh2tg4	467	1	161	161	CD
cord-310847-63gh2tg4	467	2	,	,	,
cord-310847-63gh2tg4	467	3	162	162	CD
cord-310847-63gh2tg4	468	1	This	this	DT
cord-310847-63gh2tg4	468	2	controlled	control	VBN
cord-310847-63gh2tg4	468	3	protein	protein	NN
cord-310847-63gh2tg4	468	4	degradation	degradation	NN
cord-310847-63gh2tg4	468	5	is	be	VBZ
cord-310847-63gh2tg4	468	6	important	important	JJ
cord-310847-63gh2tg4	468	7	for	for	IN
cord-310847-63gh2tg4	468	8	activation	activation	NN
cord-310847-63gh2tg4	468	9	and	and	CC
cord-310847-63gh2tg4	468	10	deactivation	deactivation	NN
cord-310847-63gh2tg4	468	11	of	of	IN
cord-310847-63gh2tg4	468	12	regulatory	regulatory	JJ
cord-310847-63gh2tg4	468	13	proteins	protein	NNS
cord-310847-63gh2tg4	468	14	involved	involve	VBN
cord-310847-63gh2tg4	468	15	in	in	IN
cord-310847-63gh2tg4	468	16	signaling	signal	VBG
cord-310847-63gh2tg4	468	17	pathways	pathway	NNS
cord-310847-63gh2tg4	468	18	that	that	WDT
cord-310847-63gh2tg4	468	19	control	control	VBP
cord-310847-63gh2tg4	468	20	cell	cell	NN
cord-310847-63gh2tg4	468	21	growth	growth	NN
cord-310847-63gh2tg4	468	22	,	,	,
cord-310847-63gh2tg4	468	23	differentiation	differentiation	NN
cord-310847-63gh2tg4	468	24	,	,	,
cord-310847-63gh2tg4	468	25	stress	stress	NN
cord-310847-63gh2tg4	468	26	responses	response	NNS
cord-310847-63gh2tg4	468	27	and	and	CC
cord-310847-63gh2tg4	468	28	physiological	physiological	JJ
cord-310847-63gh2tg4	468	29	cell	cell	NN
cord-310847-63gh2tg4	468	30	death	death	NN
cord-310847-63gh2tg4	468	31	.	.	.
cord-310847-63gh2tg4	469	1	[	[	-LRB-
cord-310847-63gh2tg4	469	2	159	159	CD
cord-310847-63gh2tg4	469	3	]	]	-RRB-
cord-310847-63gh2tg4	469	4	[	[	-LRB-
cord-310847-63gh2tg4	469	5	160	160	CD
cord-310847-63gh2tg4	469	6	]	]	-RRB-
cord-310847-63gh2tg4	469	7	[	[	-LRB-
cord-310847-63gh2tg4	469	8	161	161	CD
cord-310847-63gh2tg4	469	9	]	]	-RRB-
cord-310847-63gh2tg4	469	10	[	[	-LRB-
cord-310847-63gh2tg4	469	11	162	162	CD
cord-310847-63gh2tg4	469	12	]	]	-RRB-
cord-310847-63gh2tg4	469	13	PEST	pest	NN
cord-310847-63gh2tg4	469	14	-	-	HYPH
cord-310847-63gh2tg4	469	15	containing	contain	VBG
cord-310847-63gh2tg4	469	16	sequences	sequence	NNS
cord-310847-63gh2tg4	469	17	were	be	VBD
cord-310847-63gh2tg4	469	18	shown	show	VBN
cord-310847-63gh2tg4	469	19	to	to	TO
cord-310847-63gh2tg4	469	20	be	be	VB
cord-310847-63gh2tg4	469	21	solvent	solvent	NN
cord-310847-63gh2tg4	469	22	exposed	expose	VBN
cord-310847-63gh2tg4	469	23	and	and	CC
cord-310847-63gh2tg4	469	24	conformationally	conformationally	RB
cord-310847-63gh2tg4	469	25	flexible	flexible	JJ
cord-310847-63gh2tg4	469	26	,	,	,
cord-310847-63gh2tg4	469	27	which	which	WDT
cord-310847-63gh2tg4	469	28	preclude	preclude	VBP
cord-310847-63gh2tg4	469	29	them	-PRON-	PRP
cord-310847-63gh2tg4	469	30	from	from	IN
cord-310847-63gh2tg4	469	31	been	be	VBN
cord-310847-63gh2tg4	469	32	resolved	resolve	VBN
cord-310847-63gh2tg4	469	33	in	in	IN
cord-310847-63gh2tg4	469	34	X	x	NN
cord-310847-63gh2tg4	469	35	-	-	NN
cord-310847-63gh2tg4	469	36	ray	ray	JJ
cord-310847-63gh2tg4	469	37	structures	structure	NNS
cord-310847-63gh2tg4	469	38	.	.	.
cord-310847-63gh2tg4	470	1	159	159	CD
cord-310847-63gh2tg4	471	1	Based	base	VBN
cord-310847-63gh2tg4	471	2	on	on	IN
cord-310847-63gh2tg4	471	3	the	the	DT
cord-310847-63gh2tg4	471	4	comprehensive	comprehensive	JJ
cord-310847-63gh2tg4	471	5	bioinformatics	bioinformatic	NNS
cord-310847-63gh2tg4	471	6	analysis	analysis	NN
cord-310847-63gh2tg4	471	7	of	of	IN
cord-310847-63gh2tg4	471	8	experimentally	experimentally	RB
cord-310847-63gh2tg4	471	9	characterized	characterize	VBN
cord-310847-63gh2tg4	471	10	disordered	disordered	JJ
cord-310847-63gh2tg4	471	11	and	and	CC
cord-310847-63gh2tg4	471	12	globular	globular	JJ
cord-310847-63gh2tg4	471	13	regions	region	NNS
cord-310847-63gh2tg4	471	14	and	and	CC
cord-310847-63gh2tg4	471	15	of	of	IN
cord-310847-63gh2tg4	471	16	PDB	PDB	NNP
cord-310847-63gh2tg4	471	17	chains	chain	NNS
cord-310847-63gh2tg4	471	18	containing	contain	VBG
cord-310847-63gh2tg4	471	19	PEST	pest	NN
cord-310847-63gh2tg4	471	20	regions	region	NNS
cord-310847-63gh2tg4	471	21	,	,	,
cord-310847-63gh2tg4	471	22	it	-PRON-	PRP
cord-310847-63gh2tg4	471	23	has	have	VBZ
cord-310847-63gh2tg4	471	24	been	be	VBN
cord-310847-63gh2tg4	471	25	concluded	conclude	VBN
cord-310847-63gh2tg4	471	26	that	that	IN
cord-310847-63gh2tg4	471	27	the	the	DT
cord-310847-63gh2tg4	471	28	PEST	PEST	NNP
cord-310847-63gh2tg4	471	29	motif	motif	NN
cord-310847-63gh2tg4	471	30	is	be	VBZ
cord-310847-63gh2tg4	471	31	most	most	RBS
cord-310847-63gh2tg4	471	32	frequently	frequently	RB
cord-310847-63gh2tg4	471	33	located	locate	VBN
cord-310847-63gh2tg4	471	34	within	within	IN
cord-310847-63gh2tg4	471	35	IDPRs	idpr	NNS
cord-310847-63gh2tg4	471	36	.	.	.
cord-310847-63gh2tg4	472	1	161	161	CD
cord-310847-63gh2tg4	473	1	Furthermore	furthermore	RB
cord-310847-63gh2tg4	473	2	,	,	,
cord-310847-63gh2tg4	473	3	analysis	analysis	NN
cord-310847-63gh2tg4	473	4	of	of	IN
cord-310847-63gh2tg4	473	5	the	the	DT
cord-310847-63gh2tg4	473	6	prolinerich	prolinerich	JJ
cord-310847-63gh2tg4	473	7	motif	motif	NN
cord-310847-63gh2tg4	473	8	Pro	pro	JJ
cord-310847-63gh2tg4	473	9	-	-	JJ
cord-310847-63gh2tg4	473	10	X	x	JJ
cord-310847-63gh2tg4	473	11	-	-	HYPH
cord-310847-63gh2tg4	473	12	Pro	pro	JJ
cord-310847-63gh2tg4	473	13	-	-	JJ
cord-310847-63gh2tg4	473	14	X	x	JJ
cord-310847-63gh2tg4	473	15	-	-	HYPH
cord-310847-63gh2tg4	473	16	Pro	pro	JJ
cord-310847-63gh2tg4	473	17	in	in	IN
cord-310847-63gh2tg4	473	18	PEST	PEST	NNP
cord-310847-63gh2tg4	473	19	sequences	sequence	NNS
cord-310847-63gh2tg4	473	20	revealed	reveal	VBD
cord-310847-63gh2tg4	473	21	that	that	IN
cord-310847-63gh2tg4	473	22	these	these	DT
cord-310847-63gh2tg4	473	23	sequences	sequence	NNS
cord-310847-63gh2tg4	473	24	contain	contain	VBP
cord-310847-63gh2tg4	473	25	glutamic	glutamic	NN
cord-310847-63gh2tg4	473	26	acids	acid	NNS
cord-310847-63gh2tg4	473	27	much	much	RB
cord-310847-63gh2tg4	473	28	more	more	RBR
cord-310847-63gh2tg4	473	29	often	often	RB
cord-310847-63gh2tg4	473	30	than	than	IN
cord-310847-63gh2tg4	473	31	aspartic	aspartic	JJ
cord-310847-63gh2tg4	473	32	acids	acid	NNS
cord-310847-63gh2tg4	473	33	.	.	.
cord-310847-63gh2tg4	474	1	161	161	CD
cord-310847-63gh2tg4	475	1	In	in	IN
cord-310847-63gh2tg4	475	2	addition	addition	NN
cord-310847-63gh2tg4	475	3	to	to	IN
cord-310847-63gh2tg4	475	4	this	this	DT
cord-310847-63gh2tg4	475	5	Pro	pro	JJ
cord-310847-63gh2tg4	475	6	-	-	JJ
cord-310847-63gh2tg4	475	7	X	x	JJ
cord-310847-63gh2tg4	475	8	-	-	HYPH
cord-310847-63gh2tg4	475	9	Pro	pro	JJ
cord-310847-63gh2tg4	475	10	-	-	JJ
cord-310847-63gh2tg4	475	11	X	x	JJ
cord-310847-63gh2tg4	475	12	-	-	HYPH
cord-310847-63gh2tg4	475	13	Pro	pro	JJ
cord-310847-63gh2tg4	475	14	motif	motif	NN
cord-310847-63gh2tg4	475	15	,	,	,
cord-310847-63gh2tg4	475	16	many	many	JJ
cord-310847-63gh2tg4	475	17	PEST	pest	NN
cord-310847-63gh2tg4	475	18	sequences	sequence	NNS
cord-310847-63gh2tg4	475	19	are	be	VBP
cord-310847-63gh2tg4	475	20	highly	highly	RB
cord-310847-63gh2tg4	475	21	enriched	enrich	VBN
cord-310847-63gh2tg4	475	22	in	in	IN
cord-310847-63gh2tg4	475	23	negatively	negatively	RB
cord-310847-63gh2tg4	475	24	charged	charge	VBN
cord-310847-63gh2tg4	475	25	residues	residue	NNS
cord-310847-63gh2tg4	475	26	and	and	CC
cord-310847-63gh2tg4	475	27	are	be	VBP
cord-310847-63gh2tg4	475	28	characterized	characterize	VBN
cord-310847-63gh2tg4	475	29	by	by	IN
cord-310847-63gh2tg4	475	30	a	a	DT
cord-310847-63gh2tg4	475	31	very	very	RB
cord-310847-63gh2tg4	475	32	specific	specific	JJ
cord-310847-63gh2tg4	475	33	distribution	distribution	NN
cord-310847-63gh2tg4	475	34	of	of	IN
cord-310847-63gh2tg4	475	35	negative	negative	JJ
cord-310847-63gh2tg4	475	36	charged	charge	VBN
cord-310847-63gh2tg4	475	37	patterns	pattern	NNS
cord-310847-63gh2tg4	475	38	.	.	.
cord-310847-63gh2tg4	476	1	161	161	CD
cord-310847-63gh2tg4	476	2	Glutamic	Glutamic	NNP
cord-310847-63gh2tg4	476	3	acids	acid	NNS
cord-310847-63gh2tg4	476	4	in	in	IN
cord-310847-63gh2tg4	476	5	entropic	entropic	JJ
cord-310847-63gh2tg4	476	6	bristle	bristle	NN
cord-310847-63gh2tg4	476	7	domains	domain	NNS
cord-310847-63gh2tg4	476	8	.	.	.
cord-310847-63gh2tg4	477	1	The	the	DT
cord-310847-63gh2tg4	477	2	entropic	entropic	JJ
cord-310847-63gh2tg4	477	3	bristle	bristle	NN
cord-310847-63gh2tg4	477	4	domain	domain	NN
cord-310847-63gh2tg4	477	5	(	(	-LRB-
cord-310847-63gh2tg4	477	6	EBD	EBD	NNP
cord-310847-63gh2tg4	477	7	)	)	-RRB-
cord-310847-63gh2tg4	477	8	concept	concept	NN
cord-310847-63gh2tg4	477	9	was	be	VBD
cord-310847-63gh2tg4	477	10	proposed	propose	VBN
cord-310847-63gh2tg4	477	11	to	to	TO
cord-310847-63gh2tg4	477	12	describe	describe	VB
cord-310847-63gh2tg4	477	13	a	a	DT
cord-310847-63gh2tg4	477	14	characteristic	characteristic	JJ
cord-310847-63gh2tg4	477	15	behavior	behavior	NN
cord-310847-63gh2tg4	477	16	of	of	IN
cord-310847-63gh2tg4	477	17	some	some	DT
cord-310847-63gh2tg4	477	18	highly	highly	RB
cord-310847-63gh2tg4	477	19	mobile	mobile	JJ
cord-310847-63gh2tg4	477	20	protein	protein	NN
cord-310847-63gh2tg4	477	21	regions	region	NNS
cord-310847-63gh2tg4	477	22	.	.	.
cord-310847-63gh2tg4	478	1	The	the	DT
cord-310847-63gh2tg4	478	2	several	several	JJ
cord-310847-63gh2tg4	478	3	metals	metal	NNS
cord-310847-63gh2tg4	478	4	of	of	IN
cord-310847-63gh2tg4	478	5	the	the	DT
cord-310847-63gh2tg4	478	6	transition	transition	NN
cord-310847-63gh2tg4	478	7	and	and	CC
cord-310847-63gh2tg4	478	8	main	main	JJ
cord-310847-63gh2tg4	478	9	groups	group	NNS
cord-310847-63gh2tg4	478	10	(	(	-LRB-
cord-310847-63gh2tg4	478	11	Ib	Ib	NNP
cord-310847-63gh2tg4	478	12	-	-	HYPH
cord-310847-63gh2tg4	478	13	Va	Va	NNP
cord-310847-63gh2tg4	478	14	,	,	,
cord-310847-63gh2tg4	478	15	Z	z	NN
cord-310847-63gh2tg4	478	16	=	=	SYM
cord-310847-63gh2tg4	478	17	29−83	29−83	CD
cord-310847-63gh2tg4	478	18	)	)	-RRB-
cord-310847-63gh2tg4	478	19	of	of	IN
cord-310847-63gh2tg4	478	20	the	the	DT
cord-310847-63gh2tg4	478	21	periodic	periodic	JJ
cord-310847-63gh2tg4	478	22	table	table	NN
cord-310847-63gh2tg4	478	23	of	of	IN
cord-310847-63gh2tg4	478	24	elements	element	NNS
cord-310847-63gh2tg4	478	25	.	.	.
cord-310847-63gh2tg4	479	1	Phytochelatins	phytochelatin	NNS
cord-310847-63gh2tg4	479	2	are	be	VBP
cord-310847-63gh2tg4	479	3	synthesized	synthesize	VBN
cord-310847-63gh2tg4	479	4	by	by	IN
cord-310847-63gh2tg4	479	5	a	a	DT
cord-310847-63gh2tg4	479	6	constitutive	constitutive	JJ
cord-310847-63gh2tg4	479	7	enzyme	enzyme	NN
cord-310847-63gh2tg4	479	8	,	,	,
cord-310847-63gh2tg4	479	9	γ	γ	NN
cord-310847-63gh2tg4	479	10	-	-	HYPH
cord-310847-63gh2tg4	479	11	glutamylcysteine	glutamylcysteine	NNP
cord-310847-63gh2tg4	479	12	dipeptidyl	dipeptidyl	JJ
cord-310847-63gh2tg4	479	13	transpeptidase	transpeptidase	NNP
cord-310847-63gh2tg4	479	14	,	,	,
cord-310847-63gh2tg4	479	15	that	that	WDT
cord-310847-63gh2tg4	479	16	uses	use	VBZ
cord-310847-63gh2tg4	479	17	glutathione	glutathione	NN
cord-310847-63gh2tg4	479	18	(	(	-LRB-
cord-310847-63gh2tg4	479	19	GSH	GSH	NNP
cord-310847-63gh2tg4	479	20	)	)	-RRB-
cord-310847-63gh2tg4	479	21	as	as	IN
cord-310847-63gh2tg4	479	22	a	a	DT
cord-310847-63gh2tg4	479	23	substrate	substrate	NN
cord-310847-63gh2tg4	479	24	and	and	CC
cord-310847-63gh2tg4	479	25	catalyzes	catalyze	VBZ
cord-310847-63gh2tg4	479	26	the	the	DT
cord-310847-63gh2tg4	479	27	following	following	JJ
cord-310847-63gh2tg4	479	28	reaction	reaction	NN
cord-310847-63gh2tg4	479	29	:	:	:
cord-310847-63gh2tg4	479	30	γ	γ	NN
cord-310847-63gh2tg4	479	31	-	-	HYPH
cord-310847-63gh2tg4	479	32	Glu	Glu	NNP
cord-310847-63gh2tg4	479	33	-	-	HYPH
cord-310847-63gh2tg4	479	34	Cys	Cys	NNP
cord-310847-63gh2tg4	479	35	-	-	HYPH
cord-310847-63gh2tg4	479	36	Gly	Gly	NNP
cord-310847-63gh2tg4	479	37	+	+	CC
cord-310847-63gh2tg4	479	38	(	(	-LRB-
cord-310847-63gh2tg4	479	39	γ	γ	NN
cord-310847-63gh2tg4	479	40	-	-	HYPH
cord-310847-63gh2tg4	479	41	Glu	Glu	NNP
cord-310847-63gh2tg4	479	42	-	-	HYPH
cord-310847-63gh2tg4	479	43	Cys	Cys	NNP
cord-310847-63gh2tg4	479	44	)	)	-RRB-
cord-310847-63gh2tg4	479	45	n	n	CC
cord-310847-63gh2tg4	479	46	−	−	NNP
cord-310847-63gh2tg4	479	47	Gly→(γ	Gly→(γ	NNP
cord-310847-63gh2tg4	479	48	-	-	HYPH
cord-310847-63gh2tg4	479	49	Glu	Glu	NNP
cord-310847-63gh2tg4	479	50	-	-	HYPH
cord-310847-63gh2tg4	479	51	Cys	Cys	NNP
cord-310847-63gh2tg4	479	52	)	)	-RRB-
cord-310847-63gh2tg4	479	53	n+1	n+1	NN
cord-310847-63gh2tg4	479	54	−	−	NN
cord-310847-63gh2tg4	479	55	Gly	Gly	NNP
cord-310847-63gh2tg4	479	56	+	+	CC
cord-310847-63gh2tg4	479	57	Gly	Gly	NNP
cord-310847-63gh2tg4	479	58	.	.	.
cord-310847-63gh2tg4	480	1	183	183	CD
cord-310847-63gh2tg4	480	2	Fertilization	fertilization	NN
cord-310847-63gh2tg4	480	3	promoting	promote	VBG
cord-310847-63gh2tg4	480	4	peptide	peptide	NN
cord-310847-63gh2tg4	480	5	.	.	.
cord-310847-63gh2tg4	481	1	Another	another	DT
cord-310847-63gh2tg4	481	2	important	important	JJ
cord-310847-63gh2tg4	481	3	glutamaterich	glutamaterich	NN
cord-310847-63gh2tg4	481	4	peptide	peptide	NN
cord-310847-63gh2tg4	481	5	is	be	VBZ
cord-310847-63gh2tg4	481	6	fertilization	fertilization	NN
cord-310847-63gh2tg4	481	7	promoting	promote	VBG
cord-310847-63gh2tg4	481	8	peptide	peptide	NN
cord-310847-63gh2tg4	481	9	(	(	-LRB-
cord-310847-63gh2tg4	481	10	FPP	FPP	NNP
cord-310847-63gh2tg4	481	11	;	;	:
cord-310847-63gh2tg4	481	12	pGlu	pGlu	NNP
cord-310847-63gh2tg4	481	13	-	-	HYPH
cord-310847-63gh2tg4	481	14	Glu	Glu	NNP
cord-310847-63gh2tg4	481	15	-	-	HYPH
cord-310847-63gh2tg4	481	16	ProNH2	ProNH2	NNP
cord-310847-63gh2tg4	481	17	)	)	-RRB-
cord-310847-63gh2tg4	481	18	,	,	,
cord-310847-63gh2tg4	481	19	which	which	WDT
cord-310847-63gh2tg4	481	20	is	be	VBZ
cord-310847-63gh2tg4	481	21	produced	produce	VBN
cord-310847-63gh2tg4	481	22	by	by	IN
cord-310847-63gh2tg4	481	23	the	the	DT
cord-310847-63gh2tg4	481	24	prostate	prostate	NN
cord-310847-63gh2tg4	481	25	gland	gland	NN
cord-310847-63gh2tg4	481	26	and	and	CC
cord-310847-63gh2tg4	481	27	secreted	secrete	VBN
cord-310847-63gh2tg4	481	28	into	into	IN
cord-310847-63gh2tg4	481	29	seminal	seminal	JJ
cord-310847-63gh2tg4	481	30	plasma	plasma	NN
cord-310847-63gh2tg4	481	31	.	.	.
cord-310847-63gh2tg4	482	1	184	184	CD
cord-310847-63gh2tg4	482	2	FPP	FPP	NNP
cord-310847-63gh2tg4	482	3	was	be	VBD
cord-310847-63gh2tg4	482	4	shown	show	VBN
cord-310847-63gh2tg4	482	5	to	to	TO
cord-310847-63gh2tg4	482	6	stimulate	stimulate	VB
cord-310847-63gh2tg4	482	7	capacitation	capacitation	NN
cord-310847-63gh2tg4	482	8	,	,	,
cord-310847-63gh2tg4	482	9	which	which	WDT
cord-310847-63gh2tg4	482	10	is	be	VBZ
cord-310847-63gh2tg4	482	11	the	the	DT
cord-310847-63gh2tg4	482	12	penultimate	penultimate	JJ
cord-310847-63gh2tg4	482	13	step	step	NN
cord-310847-63gh2tg4	482	14	in	in	IN
cord-310847-63gh2tg4	482	15	the	the	DT
cord-310847-63gh2tg4	482	16	maturation	maturation	NN
cord-310847-63gh2tg4	482	17	of	of	IN
cord-310847-63gh2tg4	482	18	mammalian	mammalian	JJ
cord-310847-63gh2tg4	482	19	spermatozoa	spermatozoon	NNS
cord-310847-63gh2tg4	482	20	required	require	VBN
cord-310847-63gh2tg4	482	21	to	to	TO
cord-310847-63gh2tg4	482	22	render	render	VB
cord-310847-63gh2tg4	482	23	them	-PRON-	PRP
cord-310847-63gh2tg4	482	24	competent	competent	JJ
cord-310847-63gh2tg4	482	25	to	to	TO
cord-310847-63gh2tg4	482	26	fertilize	fertilize	VB
cord-310847-63gh2tg4	482	27	an	an	DT
cord-310847-63gh2tg4	482	28	oocyte	oocyte	NN
cord-310847-63gh2tg4	482	29	.	.	.
cord-310847-63gh2tg4	483	1	Furthermore	furthermore	RB
cord-310847-63gh2tg4	483	2	,	,	,
cord-310847-63gh2tg4	483	3	although	although	IN
cord-310847-63gh2tg4	483	4	FPP	FPP	NNP
cord-310847-63gh2tg4	483	5	inhibits	inhibit	VBZ
cord-310847-63gh2tg4	483	6	spontaneous	spontaneous	JJ
cord-310847-63gh2tg4	483	7	loss	loss	NN
cord-310847-63gh2tg4	483	8	of	of	IN
cord-310847-63gh2tg4	483	9	acrosome	acrosome	NN
cord-310847-63gh2tg4	483	10	(	(	-LRB-
cord-310847-63gh2tg4	483	11	an	an	DT
cord-310847-63gh2tg4	483	12	organelle	organelle	NN
cord-310847-63gh2tg4	483	13	that	that	WDT
cord-310847-63gh2tg4	483	14	develops	develop	VBZ
cord-310847-63gh2tg4	483	15	over	over	IN
cord-310847-63gh2tg4	483	16	the	the	DT
cord-310847-63gh2tg4	483	17	anterior	anterior	JJ
cord-310847-63gh2tg4	483	18	half	half	NN
cord-310847-63gh2tg4	483	19	of	of	IN
cord-310847-63gh2tg4	483	20	the	the	DT
cord-310847-63gh2tg4	483	21	head	head	NN
cord-310847-63gh2tg4	483	22	in	in	IN
cord-310847-63gh2tg4	483	23	the	the	DT
cord-310847-63gh2tg4	483	24	spermatozoa	spermatozoa	NN
cord-310847-63gh2tg4	483	25	)	)	-RRB-
cord-310847-63gh2tg4	483	26	,	,	,
cord-310847-63gh2tg4	483	27	cells	cell	NNS
cord-310847-63gh2tg4	483	28	retain	retain	VBP
cord-310847-63gh2tg4	483	29	high	high	JJ
cord-310847-63gh2tg4	483	30	fertility	fertility	NN
cord-310847-63gh2tg4	483	31	in	in	IN
cord-310847-63gh2tg4	483	32	vitro	vitro	FW
cord-310847-63gh2tg4	483	33	.	.	.
cord-310847-63gh2tg4	484	1	184	184	CD
cord-310847-63gh2tg4	484	2	GALA	gala	NN
cord-310847-63gh2tg4	484	3	peptide	peptide	NN
cord-310847-63gh2tg4	484	4	.	.	.
cord-310847-63gh2tg4	485	1	Recently	recently	RB
cord-310847-63gh2tg4	485	2	,	,	,
cord-310847-63gh2tg4	485	3	a	a	DT
cord-310847-63gh2tg4	485	4	synthetic	synthetic	JJ
cord-310847-63gh2tg4	485	5	30	30	CD
cord-310847-63gh2tg4	485	6	amino	amino	NN
cord-310847-63gh2tg4	485	7	acid	acid	NN
cord-310847-63gh2tg4	485	8	-	-	HYPH
cord-310847-63gh2tg4	485	9	long	long	JJ
cord-310847-63gh2tg4	485	10	GALA	gala	NN
cord-310847-63gh2tg4	485	11	peptide	peptide	NN
cord-310847-63gh2tg4	485	12	with	with	IN
cord-310847-63gh2tg4	485	13	a	a	DT
cord-310847-63gh2tg4	485	14	glutamic	glutamic	JJ
cord-310847-63gh2tg4	485	15	acid	acid	NN
cord-310847-63gh2tg4	485	16	-	-	HYPH
cord-310847-63gh2tg4	485	17	alanine	alanine	NN
cord-310847-63gh2tg4	485	18	-	-	HYPH
cord-310847-63gh2tg4	485	19	leucine	leucine	NN
cord-310847-63gh2tg4	485	20	-	-	HYPH
cord-310847-63gh2tg4	485	21	alanine	alanine	NN
cord-310847-63gh2tg4	485	22	(	(	-LRB-
cord-310847-63gh2tg4	485	23	EALA	EALA	NNP
cord-310847-63gh2tg4	485	24	)	)	-RRB-
cord-310847-63gh2tg4	485	25	repeat	repeat	NN
cord-310847-63gh2tg4	485	26	was	be	VBD
cord-310847-63gh2tg4	485	27	designed	design	VBN
cord-310847-63gh2tg4	485	28	to	to	TO
cord-310847-63gh2tg4	485	29	analyze	analyze	VB
cord-310847-63gh2tg4	485	30	how	how	WRB
cord-310847-63gh2tg4	485	31	viral	viral	JJ
cord-310847-63gh2tg4	485	32	fusion	fusion	NN
cord-310847-63gh2tg4	485	33	protein	protein	NN
cord-310847-63gh2tg4	485	34	sequences	sequence	NNS
cord-310847-63gh2tg4	485	35	interact	interact	VBP
cord-310847-63gh2tg4	485	36	with	with	IN
cord-310847-63gh2tg4	485	37	membranes	membrane	NNS
cord-310847-63gh2tg4	485	38	.	.	.
cord-310847-63gh2tg4	486	1	185	185	CD
cord-310847-63gh2tg4	487	1	This	this	DT
cord-310847-63gh2tg4	487	2	GALA	gala	NN
cord-310847-63gh2tg4	487	3	peptide	peptide	NN
cord-310847-63gh2tg4	487	4	was	be	VBD
cord-310847-63gh2tg4	487	5	long	long	RB
cord-310847-63gh2tg4	487	6	enough	enough	RB
cord-310847-63gh2tg4	487	7	to	to	TO
cord-310847-63gh2tg4	487	8	span	span	VB
cord-310847-63gh2tg4	487	9	a	a	DT
cord-310847-63gh2tg4	487	10	bilayer	bilayer	NN
cord-310847-63gh2tg4	487	11	when	when	WRB
cord-310847-63gh2tg4	487	12	in	in	IN
cord-310847-63gh2tg4	487	13	the	the	DT
cord-310847-63gh2tg4	487	14	α	α	NN
cord-310847-63gh2tg4	487	15	-	-	HYPH
cord-310847-63gh2tg4	487	16	helical	helical	JJ
cord-310847-63gh2tg4	487	17	state	state	NN
cord-310847-63gh2tg4	487	18	,	,	,
cord-310847-63gh2tg4	487	19	and	and	CC
cord-310847-63gh2tg4	487	20	the	the	DT
cord-310847-63gh2tg4	487	21	EALA	EALA	NNP
cord-310847-63gh2tg4	487	22	repeat	repeat	NN
cord-310847-63gh2tg4	487	23	was	be	VBD
cord-310847-63gh2tg4	487	24	adjusted	adjust	VBN
cord-310847-63gh2tg4	487	25	so	so	IN
cord-310847-63gh2tg4	487	26	that	that	IN
cord-310847-63gh2tg4	487	27	the	the	DT
cord-310847-63gh2tg4	487	28	peptide	peptide	NN
cord-310847-63gh2tg4	487	29	would	would	MD
cord-310847-63gh2tg4	487	30	have	have	VB
cord-310847-63gh2tg4	487	31	a	a	DT
cord-310847-63gh2tg4	487	32	hydrophobic	hydrophobic	JJ
cord-310847-63gh2tg4	487	33	face	face	NN
cord-310847-63gh2tg4	487	34	of	of	IN
cord-310847-63gh2tg4	487	35	sufficient	sufficient	JJ
cord-310847-63gh2tg4	487	36	hydrophobicity	hydrophobicity	NN
cord-310847-63gh2tg4	487	37	to	to	TO
cord-310847-63gh2tg4	487	38	interact	interact	VB
cord-310847-63gh2tg4	487	39	with	with	IN
cord-310847-63gh2tg4	487	40	the	the	DT
cord-310847-63gh2tg4	487	41	bilayer	bilayer	NN
cord-310847-63gh2tg4	487	42	when	when	WRB
cord-310847-63gh2tg4	487	43	the	the	DT
cord-310847-63gh2tg4	487	44	peptide	peptide	NN
cord-310847-63gh2tg4	487	45	was	be	VBD
cord-310847-63gh2tg4	487	46	in	in	IN
cord-310847-63gh2tg4	487	47	an	an	DT
cord-310847-63gh2tg4	487	48	α	α	NN
cord-310847-63gh2tg4	487	49	-	-	HYPH
cord-310847-63gh2tg4	487	50	helix	helix	NN
cord-310847-63gh2tg4	487	51	.	.	.
cord-310847-63gh2tg4	488	1	Glu	Glu	NNP
cord-310847-63gh2tg4	488	2	residues	residue	NNS
cord-310847-63gh2tg4	488	3	were	be	VBD
cord-310847-63gh2tg4	488	4	used	use	VBN
cord-310847-63gh2tg4	488	5	in	in	IN
cord-310847-63gh2tg4	488	6	GALA	GALA	NNP
cord-310847-63gh2tg4	488	7	as	as	IN
cord-310847-63gh2tg4	488	8	a	a	DT
cord-310847-63gh2tg4	488	9	pH	ph	JJ
cord-310847-63gh2tg4	488	10	-	-	HYPH
cord-310847-63gh2tg4	488	11	responsive	responsive	JJ
cord-310847-63gh2tg4	488	12	elements	element	NNS
cord-310847-63gh2tg4	488	13	.	.	.
cord-310847-63gh2tg4	489	1	185	185	CD
cord-310847-63gh2tg4	490	1	When	when	WRB
cord-310847-63gh2tg4	490	2	the	the	DT
cord-310847-63gh2tg4	490	3	pH	pH	NNP
cord-310847-63gh2tg4	490	4	is	be	VBZ
cord-310847-63gh2tg4	490	5	reduced	reduce	VBN
cord-310847-63gh2tg4	490	6	from	from	IN
cord-310847-63gh2tg4	490	7	7.0	7.0	CD
cord-310847-63gh2tg4	490	8	to	to	IN
cord-310847-63gh2tg4	490	9	5.0	5.0	CD
cord-310847-63gh2tg4	490	10	,	,	,
cord-310847-63gh2tg4	490	11	GALA	gala	NN
cord-310847-63gh2tg4	490	12	converts	convert	VBZ
cord-310847-63gh2tg4	490	13	from	from	IN
cord-310847-63gh2tg4	490	14	a	a	DT
cord-310847-63gh2tg4	490	15	water	water	NN
cord-310847-63gh2tg4	490	16	soluble	soluble	JJ
cord-310847-63gh2tg4	490	17	random	random	JJ
cord-310847-63gh2tg4	490	18	coil	coil	NN
cord-310847-63gh2tg4	490	19	conformation	conformation	NN
cord-310847-63gh2tg4	490	20	to	to	IN
cord-310847-63gh2tg4	490	21	an	an	DT
cord-310847-63gh2tg4	490	22	amphipathic	amphipathic	JJ
cord-310847-63gh2tg4	490	23	α	α	NN
cord-310847-63gh2tg4	490	24	-	-	HYPH
cord-310847-63gh2tg4	490	25	helix	helix	NNP
cord-310847-63gh2tg4	490	26	that	that	WDT
cord-310847-63gh2tg4	490	27	binds	bind	VBZ
cord-310847-63gh2tg4	490	28	to	to	IN
cord-310847-63gh2tg4	490	29	bilayer	bilayer	NN
cord-310847-63gh2tg4	490	30	membranes	membrane	NNS
cord-310847-63gh2tg4	490	31	.	.	.
cord-310847-63gh2tg4	491	1	Functional	functional	JJ
cord-310847-63gh2tg4	491	2	analysis	analysis	NN
cord-310847-63gh2tg4	491	3	revealed	reveal	VBD
cord-310847-63gh2tg4	491	4	that	that	IN
cord-310847-63gh2tg4	491	5	GALA	GALA	NNP
cord-310847-63gh2tg4	491	6	promoted	promote	VBD
cord-310847-63gh2tg4	491	7	fusion	fusion	NN
cord-310847-63gh2tg4	491	8	between	between	IN
cord-310847-63gh2tg4	491	9	small	small	JJ
cord-310847-63gh2tg4	491	10	unilamellar	unilamellar	NNP
cord-310847-63gh2tg4	491	11	vesicles	vesicle	NNS
cord-310847-63gh2tg4	491	12	and	and	CC
cord-310847-63gh2tg4	491	13	was	be	VBD
cord-310847-63gh2tg4	491	14	able	able	JJ
cord-310847-63gh2tg4	491	15	to	to	TO
cord-310847-63gh2tg4	491	16	form	form	VB
cord-310847-63gh2tg4	491	17	a	a	DT
cord-310847-63gh2tg4	491	18	transmembrane	transmembrane	NN
cord-310847-63gh2tg4	491	19	pore	pore	NN
cord-310847-63gh2tg4	491	20	comprised	comprise	VBN
cord-310847-63gh2tg4	491	21	of	of	IN
cord-310847-63gh2tg4	491	22	~10	~10	CD
cord-310847-63gh2tg4	491	23	GALA	GALA	NNP
cord-310847-63gh2tg4	491	24	α	α	NN
cord-310847-63gh2tg4	491	25	-	-	HYPH
cord-310847-63gh2tg4	491	26	helical	helical	JJ
cord-310847-63gh2tg4	491	27	monomers	monomer	NNS
cord-310847-63gh2tg4	491	28	that	that	WDT
cord-310847-63gh2tg4	491	29	were	be	VBD
cord-310847-63gh2tg4	491	30	oriented	orient	VBN
cord-310847-63gh2tg4	491	31	perpendicularly	perpendicularly	RB
cord-310847-63gh2tg4	491	32	to	to	IN
cord-310847-63gh2tg4	491	33	the	the	DT
cord-310847-63gh2tg4	491	34	plane	plane	NN
cord-310847-63gh2tg4	491	35	of	of	IN
cord-310847-63gh2tg4	491	36	the	the	DT
cord-310847-63gh2tg4	491	37	membrane	membrane	NN
cord-310847-63gh2tg4	491	38	.	.	.
cord-310847-63gh2tg4	492	1	185	185	CD
cord-310847-63gh2tg4	493	1	Based	base	VBN
cord-310847-63gh2tg4	493	2	on	on	IN
cord-310847-63gh2tg4	493	3	these	these	DT
cord-310847-63gh2tg4	493	4	observations	observation	NNS
cord-310847-63gh2tg4	493	5	,	,	,
cord-310847-63gh2tg4	493	6	it	-PRON-	PRP
cord-310847-63gh2tg4	493	7	has	have	VBZ
cord-310847-63gh2tg4	493	8	been	be	VBN
cord-310847-63gh2tg4	493	9	proposed	propose	VBN
cord-310847-63gh2tg4	493	10	that	that	IN
cord-310847-63gh2tg4	493	11	pH	ph	NN
cord-310847-63gh2tg4	493	12	-	-	HYPH
cord-310847-63gh2tg4	493	13	controlled	control	VBN
cord-310847-63gh2tg4	493	14	membrane	membrane	NN
cord-310847-63gh2tg4	493	15	permealization	permealization	NN
cord-310847-63gh2tg4	493	16	induced	induce	VBN
cord-310847-63gh2tg4	493	17	by	by	IN
cord-310847-63gh2tg4	493	18	GALA	GALA	NNP
cord-310847-63gh2tg4	493	19	can	can	MD
cord-310847-63gh2tg4	493	20	serve	serve	VB
cord-310847-63gh2tg4	493	21	as	as	IN
cord-310847-63gh2tg4	493	22	a	a	DT
cord-310847-63gh2tg4	493	23	model	model	NN
cord-310847-63gh2tg4	493	24	for	for	IN
cord-310847-63gh2tg4	493	25	the	the	DT
cord-310847-63gh2tg4	493	26	design	design	NN
cord-310847-63gh2tg4	493	27	of	of	IN
cord-310847-63gh2tg4	493	28	environmentally	environmentally	RB
cord-310847-63gh2tg4	493	29	responsive	responsive	JJ
cord-310847-63gh2tg4	493	30	peptidic	peptidic	JJ
cord-310847-63gh2tg4	493	31	vehicles	vehicle	NNS
cord-310847-63gh2tg4	493	32	for	for	IN
cord-310847-63gh2tg4	493	33	drugs	drug	NNS
cord-310847-63gh2tg4	493	34	and	and	CC
cord-310847-63gh2tg4	493	35	genes	gene	NNS
cord-310847-63gh2tg4	493	36	delivery	delivery	NN
cord-310847-63gh2tg4	493	37	.	.	.
cord-310847-63gh2tg4	494	1	185	185	CD
cord-310847-63gh2tg4	494	2	Other	other	JJ
cord-310847-63gh2tg4	494	3	type	type	NN
cord-310847-63gh2tg4	494	4	of	of	IN
cord-310847-63gh2tg4	494	5	PESTs	pest	NNS
cord-310847-63gh2tg4	494	6	:	:	:
cord-310847-63gh2tg4	494	7	PTP	ptp	NN
cord-310847-63gh2tg4	494	8	-	-	HYPH
cord-310847-63gh2tg4	494	9	PESTs	pest	NNS
cord-310847-63gh2tg4	494	10	.	.	.
cord-310847-63gh2tg4	495	1	Protein	protein	NN
cord-310847-63gh2tg4	495	2	tyrosine	tyrosine	NN
cord-310847-63gh2tg4	495	3	phosphatases	phosphatase	NNS
cord-310847-63gh2tg4	495	4	(	(	-LRB-
cord-310847-63gh2tg4	495	5	PTP	PTP	NNP
cord-310847-63gh2tg4	495	6	)	)	-RRB-
cord-310847-63gh2tg4	495	7	with	with	IN
cord-310847-63gh2tg4	495	8	proline-	proline-	NNP
cord-310847-63gh2tg4	495	9	,	,	,
cord-310847-63gh2tg4	495	10	glutamate-	glutamate-	NNS
cord-310847-63gh2tg4	495	11	,	,	,
cord-310847-63gh2tg4	495	12	serine	serine	NN
cord-310847-63gh2tg4	495	13	-	-	HYPH
cord-310847-63gh2tg4	495	14	and	and	CC
cord-310847-63gh2tg4	495	15	threoninerich	threoninerich	NN
cord-310847-63gh2tg4	495	16	sequence	sequence	NN
cord-310847-63gh2tg4	495	17	,	,	,
cord-310847-63gh2tg4	495	18	PTPs	ptp	NNS
cord-310847-63gh2tg4	495	19	-	-	HYPH
cord-310847-63gh2tg4	495	20	PEST	PEST	NNP
cord-310847-63gh2tg4	495	21	,	,	,
cord-310847-63gh2tg4	495	22	are	be	VBP
cord-310847-63gh2tg4	495	23	a	a	DT
cord-310847-63gh2tg4	495	24	ubiquitously	ubiquitously	RB
cord-310847-63gh2tg4	495	25	expressed	express	VBN
cord-310847-63gh2tg4	495	26	critical	critical	JJ
cord-310847-63gh2tg4	495	27	regulators	regulator	NNS
cord-310847-63gh2tg4	495	28	of	of	IN
cord-310847-63gh2tg4	495	29	cell	cell	NN
cord-310847-63gh2tg4	495	30	adhesion	adhesion	NN
cord-310847-63gh2tg4	495	31	and	and	CC
cord-310847-63gh2tg4	495	32	migration	migration	NN
cord-310847-63gh2tg4	495	33	.	.	.
cord-310847-63gh2tg4	496	1	186	186	CD
cord-310847-63gh2tg4	496	2	,	,	,
cord-310847-63gh2tg4	496	3	187	187	CD
cord-310847-63gh2tg4	497	1	This	this	DT
cord-310847-63gh2tg4	497	2	family	family	NN
cord-310847-63gh2tg4	497	3	of	of	IN
cord-310847-63gh2tg4	497	4	PTPs	ptp	NNS
cord-310847-63gh2tg4	497	5	includes	include	VBZ
cord-310847-63gh2tg4	497	6	three	three	CD
cord-310847-63gh2tg4	497	7	intracellular	intracellular	JJ
cord-310847-63gh2tg4	497	8	phosphatases	phosphatase	NNS
cord-310847-63gh2tg4	497	9	known	know	VBN
cord-310847-63gh2tg4	497	10	as	as	IN
cord-310847-63gh2tg4	497	11	prolineenriched	prolineenriched	NN
cord-310847-63gh2tg4	497	12	phosphatase	phosphatase	NN
cord-310847-63gh2tg4	497	13	(	(	-LRB-
cord-310847-63gh2tg4	497	14	PEP	pep	NN
cord-310847-63gh2tg4	497	15	)	)	-RRB-
cord-310847-63gh2tg4	497	16	in	in	IN
cord-310847-63gh2tg4	497	17	mice	mouse	NNS
cord-310847-63gh2tg4	497	18	or	or	CC
cord-310847-63gh2tg4	497	19	lymphoid	lymphoid	JJ
cord-310847-63gh2tg4	497	20	tyrosine	tyrosine	NN
cord-310847-63gh2tg4	497	21	phosphatase	phosphatase	NN
cord-310847-63gh2tg4	497	22	(	(	-LRB-
cord-310847-63gh2tg4	497	23	LYP	LYP	NNP
cord-310847-63gh2tg4	497	24	)	)	-RRB-
cord-310847-63gh2tg4	497	25	in	in	IN
cord-310847-63gh2tg4	497	26	humans	human	NNS
cord-310847-63gh2tg4	497	27	(	(	-LRB-
cord-310847-63gh2tg4	497	28	also	also	RB
cord-310847-63gh2tg4	497	29	known	know	VBN
cord-310847-63gh2tg4	497	30	as	as	IN
cord-310847-63gh2tg4	497	31	PTPN22	PTPN22	NNP
cord-310847-63gh2tg4	497	32	and	and	CC
cord-310847-63gh2tg4	497	33	PTPN8	PTPN8	NNP
cord-310847-63gh2tg4	497	34	)	)	-RRB-
cord-310847-63gh2tg4	497	35	,	,	,
cord-310847-63gh2tg4	497	36	PTP	PTP	NNP
cord-310847-63gh2tg4	497	37	-	-	HYPH
cord-310847-63gh2tg4	497	38	PEST	PEST	NNP
cord-310847-63gh2tg4	497	39	(	(	-LRB-
cord-310847-63gh2tg4	497	40	also	also	RB
cord-310847-63gh2tg4	497	41	referred	refer	VBN
cord-310847-63gh2tg4	497	42	to	to	IN
cord-310847-63gh2tg4	497	43	as	as	IN
cord-310847-63gh2tg4	497	44	PTPN12	ptpn12	CD
cord-310847-63gh2tg4	497	45	)	)	-RRB-
cord-310847-63gh2tg4	497	46	and	and	CC
cord-310847-63gh2tg4	497	47	PTP	ptp	NN
cord-310847-63gh2tg4	497	48	-	-	HYPH
cord-310847-63gh2tg4	497	49	hematopoietic	hematopoietic	JJ
cord-310847-63gh2tg4	497	50	stem	stem	NN
cord-310847-63gh2tg4	497	51	cell	cell	NN
cord-310847-63gh2tg4	497	52	fraction	fraction	NN
cord-310847-63gh2tg4	497	53	(	(	-LRB-
cord-310847-63gh2tg4	497	54	PTP	PTP	NNP
cord-310847-63gh2tg4	497	55	-	-	HYPH
cord-310847-63gh2tg4	497	56	HSCF	HSCF	NNP
cord-310847-63gh2tg4	497	57	,	,	,
cord-310847-63gh2tg4	497	58	which	which	WDT
cord-310847-63gh2tg4	497	59	is	be	VBZ
cord-310847-63gh2tg4	497	60	also	also	RB
cord-310847-63gh2tg4	497	61	known	know	VBN
cord-310847-63gh2tg4	497	62	by	by	IN
cord-310847-63gh2tg4	497	63	several	several	JJ
cord-310847-63gh2tg4	497	64	other	other	JJ
cord-310847-63gh2tg4	497	65	names	name	NNS
cord-310847-63gh2tg4	497	66	,	,	,
cord-310847-63gh2tg4	497	67	such	such	JJ
cord-310847-63gh2tg4	497	68	as	as	IN
cord-310847-63gh2tg4	497	69	also	also	RB
cord-310847-63gh2tg4	497	70	termed	term	VBN
cord-310847-63gh2tg4	497	71	brain	brain	NN
cord-310847-63gh2tg4	497	72	-	-	HYPH
cord-310847-63gh2tg4	497	73	derived	derive	VBN
cord-310847-63gh2tg4	497	74	phosphatase	phosphatase	NN
cord-310847-63gh2tg4	497	75	1	1	CD
cord-310847-63gh2tg4	497	76	(	(	-LRB-
cord-310847-63gh2tg4	497	77	BDP1	BDP1	NNP
cord-310847-63gh2tg4	497	78	)	)	-RRB-
cord-310847-63gh2tg4	497	79	,	,	,
cord-310847-63gh2tg4	497	80	PTP20	PTP20	NNP
cord-310847-63gh2tg4	497	81	,	,	,
cord-310847-63gh2tg4	497	82	PTP	PTP	NNP
cord-310847-63gh2tg4	497	83	-	-	HYPH
cord-310847-63gh2tg4	497	84	K1	K1	NNP
cord-310847-63gh2tg4	497	85	,	,	,
cord-310847-63gh2tg4	497	86	fetal	fetal	JJ
cord-310847-63gh2tg4	497	87	liver	liver	NN
cord-310847-63gh2tg4	497	88	phosphatase	phosphatase	NN
cord-310847-63gh2tg4	497	89	1	1	CD
cord-310847-63gh2tg4	497	90	(	(	-LRB-
cord-310847-63gh2tg4	497	91	FLP1	FLP1	NNP
cord-310847-63gh2tg4	497	92	)	)	-RRB-
cord-310847-63gh2tg4	497	93	and	and	CC
cord-310847-63gh2tg4	498	1	PTPN18	ptpn18	UH
cord-310847-63gh2tg4	498	2	.	.	.
cord-310847-63gh2tg4	499	1	186	186	CD
cord-310847-63gh2tg4	500	1	All	all	PDT
cord-310847-63gh2tg4	500	2	these	these	DT
cord-310847-63gh2tg4	500	3	phosphatases	phosphatase	NNS
cord-310847-63gh2tg4	500	4	possess	possess	VBP
cord-310847-63gh2tg4	500	5	a	a	DT
cord-310847-63gh2tg4	500	6	common	common	JJ
cord-310847-63gh2tg4	500	7	structural	structural	JJ
cord-310847-63gh2tg4	500	8	organization	organization	NN
cord-310847-63gh2tg4	500	9	that	that	WDT
cord-310847-63gh2tg4	500	10	includes	include	VBZ
cord-310847-63gh2tg4	500	11	an	an	DT
cord-310847-63gh2tg4	500	12	N	n	NN
cord-310847-63gh2tg4	500	13	-	-	HYPH
cord-310847-63gh2tg4	500	14	terminally	terminally	RB
cord-310847-63gh2tg4	500	15	located	locate	VBN
cord-310847-63gh2tg4	500	16	phosphatase	phosphatase	NN
cord-310847-63gh2tg4	500	17	domain	domain	NN
cord-310847-63gh2tg4	500	18	,	,	,
cord-310847-63gh2tg4	500	19	followed	follow	VBN
cord-310847-63gh2tg4	500	20	by	by	IN
cord-310847-63gh2tg4	500	21	a	a	DT
cord-310847-63gh2tg4	500	22	highly	highly	RB
cord-310847-63gh2tg4	500	23	divergent	divergent	JJ
cord-310847-63gh2tg4	500	24	central	central	JJ
cord-310847-63gh2tg4	500	25	region	region	NN
cord-310847-63gh2tg4	500	26	that	that	WDT
cord-310847-63gh2tg4	500	27	contains	contain	VBZ
cord-310847-63gh2tg4	500	28	various	various	JJ
cord-310847-63gh2tg4	500	29	motifs	motif	NNS
cord-310847-63gh2tg4	500	30	for	for	IN
cord-310847-63gh2tg4	500	31	interactions	interaction	NNS
cord-310847-63gh2tg4	500	32	with	with	IN
cord-310847-63gh2tg4	500	33	other	other	JJ
cord-310847-63gh2tg4	500	34	proteins	protein	NNS
cord-310847-63gh2tg4	500	35	,	,	,
cord-310847-63gh2tg4	500	36	and	and	CC
cord-310847-63gh2tg4	500	37	a	a	DT
cord-310847-63gh2tg4	500	38	conserved	conserved	JJ
cord-310847-63gh2tg4	500	39	C	c	NN
cord-310847-63gh2tg4	500	40	-	-	HYPH
cord-310847-63gh2tg4	500	41	terminal	terminal	NN
cord-310847-63gh2tg4	500	42	domain	domain	NN
cord-310847-63gh2tg4	500	43	known	know	VBN
cord-310847-63gh2tg4	500	44	as	as	IN
cord-310847-63gh2tg4	500	45	carboxyl	carboxyl	NN
cord-310847-63gh2tg4	500	46	-	-	HYPH
cord-310847-63gh2tg4	500	47	terminal	terminal	NN
cord-310847-63gh2tg4	500	48	homology	homology	NN
cord-310847-63gh2tg4	500	49	(	(	-LRB-
cord-310847-63gh2tg4	500	50	CTH	CTH	NNP
cord-310847-63gh2tg4	500	51	)	)	-RRB-
cord-310847-63gh2tg4	500	52	domain	domain	NN
cord-310847-63gh2tg4	500	53	.	.	.
cord-310847-63gh2tg4	501	1	186	186	CD
cord-310847-63gh2tg4	501	2	Human	human	JJ
cord-310847-63gh2tg4	501	3	PTP	PTP	NNP
cord-310847-63gh2tg4	501	4	-	-	HYPH
cord-310847-63gh2tg4	501	5	LYP	LYP	NNP
cord-310847-63gh2tg4	501	6	(	(	-LRB-
cord-310847-63gh2tg4	502	1	PTPN22/	PTPN22/	NNP
cord-310847-63gh2tg4	503	1	PTPN8	PTPN8	NNP
cord-310847-63gh2tg4	503	2	)	)	-RRB-
cord-310847-63gh2tg4	503	3	is	be	VBZ
cord-310847-63gh2tg4	503	4	a	a	DT
cord-310847-63gh2tg4	503	5	807	807	CD
cord-310847-63gh2tg4	503	6	residues	residue	NNS
cord-310847-63gh2tg4	503	7	-	-	HYPH
cord-310847-63gh2tg4	503	8	long	long	JJ
cord-310847-63gh2tg4	503	9	protein	protein	NN
cord-310847-63gh2tg4	503	10	that	that	WDT
cord-310847-63gh2tg4	503	11	contains	contain	VBZ
cord-310847-63gh2tg4	503	12	59	59	CD
cord-310847-63gh2tg4	503	13	and	and	CC
cord-310847-63gh2tg4	503	14	40	40	CD
cord-310847-63gh2tg4	503	15	glutamic	glutamic	NN
cord-310847-63gh2tg4	503	16	and	and	CC
cord-310847-63gh2tg4	503	17	aspartic	aspartic	JJ
cord-310847-63gh2tg4	503	18	acids	acid	NNS
cord-310847-63gh2tg4	503	19	and	and	CC
cord-310847-63gh2tg4	503	20	45	45	CD
cord-310847-63gh2tg4	503	21	,	,	,
cord-310847-63gh2tg4	503	22	83	83	CD
cord-310847-63gh2tg4	503	23	and	and	CC
cord-310847-63gh2tg4	503	24	32	32	CD
cord-310847-63gh2tg4	503	25	prolines	proline	NNS
cord-310847-63gh2tg4	503	26	,	,	,
cord-310847-63gh2tg4	503	27	serines	serines	NNPS
cord-310847-63gh2tg4	503	28	and	and	CC
cord-310847-63gh2tg4	503	29	threonines	threonine	NNS
cord-310847-63gh2tg4	503	30	,	,	,
cord-310847-63gh2tg4	503	31	respectively	respectively	RB
cord-310847-63gh2tg4	503	32	.	.	.
cord-310847-63gh2tg4	504	1	Human	human	JJ
cord-310847-63gh2tg4	504	2	PTP	PTP	NNP
cord-310847-63gh2tg4	504	3	-	-	HYPH
cord-310847-63gh2tg4	504	4	PEST	PEST	NNP
cord-310847-63gh2tg4	504	5	(	(	-LRB-
cord-310847-63gh2tg4	504	6	PTPN12	ptpn12	NN
cord-310847-63gh2tg4	504	7	)	)	-RRB-
cord-310847-63gh2tg4	504	8	consists	consist	VBZ
cord-310847-63gh2tg4	504	9	of	of	IN
cord-310847-63gh2tg4	504	10	780	780	CD
cord-310847-63gh2tg4	504	11	residues	residue	NNS
cord-310847-63gh2tg4	504	12	and	and	CC
cord-310847-63gh2tg4	504	13	has	have	VBZ
cord-310847-63gh2tg4	504	14	67	67	CD
cord-310847-63gh2tg4	504	15	,	,	,
cord-310847-63gh2tg4	504	16	49	49	CD
cord-310847-63gh2tg4	504	17	,	,	,
cord-310847-63gh2tg4	504	18	66	66	CD
cord-310847-63gh2tg4	504	19	,	,	,
cord-310847-63gh2tg4	504	20	72	72	CD
cord-310847-63gh2tg4	504	21	and	and	CC
cord-310847-63gh2tg4	504	22	54	54	CD
cord-310847-63gh2tg4	504	23	glutamates	glutamate	NNS
cord-310847-63gh2tg4	504	24	,	,	,
cord-310847-63gh2tg4	504	25	aspartates	aspartates	NNPS
cord-310847-63gh2tg4	504	26	,	,	,
cord-310847-63gh2tg4	504	27	prolines	prolines	NNP
cord-310847-63gh2tg4	504	28	,	,	,
cord-310847-63gh2tg4	504	29	serines	serines	NNPS
cord-310847-63gh2tg4	504	30	and	and	CC
cord-310847-63gh2tg4	504	31	threonines	threonine	NNS
cord-310847-63gh2tg4	504	32	,	,	,
cord-310847-63gh2tg4	504	33	respectively	respectively	RB
cord-310847-63gh2tg4	504	34	,	,	,
cord-310847-63gh2tg4	504	35	most	most	JJS
cord-310847-63gh2tg4	504	36	of	of	IN
cord-310847-63gh2tg4	504	37	Recently	recently	RB
cord-310847-63gh2tg4	504	38	,	,	,
cord-310847-63gh2tg4	504	39	we	-PRON-	PRP
cord-310847-63gh2tg4	504	40	proposed	propose	VBD
cord-310847-63gh2tg4	504	41	that	that	IN
cord-310847-63gh2tg4	504	42	EBDs	ebd	NNS
cord-310847-63gh2tg4	504	43	can	can	MD
cord-310847-63gh2tg4	504	44	be	be	VB
cord-310847-63gh2tg4	504	45	used	use	VBN
cord-310847-63gh2tg4	504	46	as	as	IN
cord-310847-63gh2tg4	504	47	protein	protein	NN
cord-310847-63gh2tg4	504	48	solubility	solubility	NN
cord-310847-63gh2tg4	504	49	enhancers	enhancer	NNS
cord-310847-63gh2tg4	504	50	.	.	.
cord-310847-63gh2tg4	505	1	168	168	CD
cord-310847-63gh2tg4	506	1	In	in	IN
cord-310847-63gh2tg4	506	2	fact	fact	NN
cord-310847-63gh2tg4	506	3	,	,	,
cord-310847-63gh2tg4	506	4	we	-PRON-	PRP
cord-310847-63gh2tg4	506	5	showed	show	VBD
cord-310847-63gh2tg4	506	6	that	that	IN
cord-310847-63gh2tg4	506	7	highly	highly	RB
cord-310847-63gh2tg4	506	8	charged	charge	VBN
cord-310847-63gh2tg4	506	9	protein	protein	NN
cord-310847-63gh2tg4	506	10	sequences	sequence	NNS
cord-310847-63gh2tg4	506	11	(	(	-LRB-
cord-310847-63gh2tg4	506	12	both	both	DT
cord-310847-63gh2tg4	506	13	natural	natural	JJ
cord-310847-63gh2tg4	506	14	and	and	CC
cord-310847-63gh2tg4	506	15	artificial	artificial	JJ
cord-310847-63gh2tg4	506	16	)	)	-RRB-
cord-310847-63gh2tg4	506	17	can	can	MD
cord-310847-63gh2tg4	506	18	act	act	VB
cord-310847-63gh2tg4	506	19	as	as	IN
cord-310847-63gh2tg4	506	20	EBDs	ebd	NNS
cord-310847-63gh2tg4	506	21	,	,	,
cord-310847-63gh2tg4	506	22	and	and	CC
cord-310847-63gh2tg4	506	23	that	that	IN
cord-310847-63gh2tg4	506	24	translational	translational	JJ
cord-310847-63gh2tg4	506	25	fusion	fusion	NN
cord-310847-63gh2tg4	506	26	of	of	IN
cord-310847-63gh2tg4	506	27	such	such	JJ
cord-310847-63gh2tg4	506	28	sequences	sequence	NNS
cord-310847-63gh2tg4	506	29	to	to	TO
cord-310847-63gh2tg4	506	30	target	target	VB
cord-310847-63gh2tg4	506	31	proteins	protein	NNS
cord-310847-63gh2tg4	506	32	can	can	MD
cord-310847-63gh2tg4	506	33	serve	serve	VB
cord-310847-63gh2tg4	506	34	as	as	IN
cord-310847-63gh2tg4	506	35	an	an	DT
cord-310847-63gh2tg4	506	36	effective	effective	JJ
cord-310847-63gh2tg4	506	37	solubilizing	solubilizing	NN
cord-310847-63gh2tg4	506	38	means	mean	NNS
cord-310847-63gh2tg4	506	39	by	by	IN
cord-310847-63gh2tg4	506	40	creating	create	VBG
cord-310847-63gh2tg4	506	41	both	both	DT
cord-310847-63gh2tg4	506	42	large	large	JJ
cord-310847-63gh2tg4	506	43	favorable	favorable	JJ
cord-310847-63gh2tg4	506	44	surface	surface	NN
cord-310847-63gh2tg4	506	45	area	area	NN
cord-310847-63gh2tg4	506	46	for	for	IN
cord-310847-63gh2tg4	506	47	water	water	NN
cord-310847-63gh2tg4	506	48	interactions	interaction	NNS
cord-310847-63gh2tg4	506	49	and	and	CC
cord-310847-63gh2tg4	506	50	large	large	JJ
cord-310847-63gh2tg4	506	51	excluded	exclude	VBN
cord-310847-63gh2tg4	506	52	volumes	volume	NNS
cord-310847-63gh2tg4	506	53	around	around	IN
cord-310847-63gh2tg4	506	54	the	the	DT
cord-310847-63gh2tg4	506	55	partner	partner	NN
cord-310847-63gh2tg4	506	56	.	.	.
cord-310847-63gh2tg4	507	1	168	168	CD
cord-310847-63gh2tg4	508	1	This	this	DT
cord-310847-63gh2tg4	508	2	suggests	suggest	VBZ
cord-310847-63gh2tg4	508	3	that	that	IN
cord-310847-63gh2tg4	508	4	intrinsically	intrinsically	RB
cord-310847-63gh2tg4	508	5	disordered	disordered	JJ
cord-310847-63gh2tg4	508	6	EBDs	ebd	NNS
cord-310847-63gh2tg4	508	7	(	(	-LRB-
cord-310847-63gh2tg4	508	8	which	which	WDT
cord-310847-63gh2tg4	508	9	extend	extend	VBP
cord-310847-63gh2tg4	508	10	away	away	RB
cord-310847-63gh2tg4	508	11	from	from	IN
cord-310847-63gh2tg4	508	12	the	the	DT
cord-310847-63gh2tg4	508	13	partner	partner	NN
cord-310847-63gh2tg4	508	14	and	and	CC
cord-310847-63gh2tg4	508	15	sweep	sweep	VB
cord-310847-63gh2tg4	508	16	out	out	RP
cord-310847-63gh2tg4	508	17	large	large	JJ
cord-310847-63gh2tg4	508	18	molecules	molecule	NNS
cord-310847-63gh2tg4	508	19	)	)	-RRB-
cord-310847-63gh2tg4	508	20	can	can	MD
cord-310847-63gh2tg4	508	21	enable	enable	VB
cord-310847-63gh2tg4	508	22	the	the	DT
cord-310847-63gh2tg4	508	23	target	target	NN
cord-310847-63gh2tg4	508	24	protein	protein	NN
cord-310847-63gh2tg4	508	25	to	to	TO
cord-310847-63gh2tg4	508	26	fold	fold	VB
cord-310847-63gh2tg4	508	27	free	free	JJ
cord-310847-63gh2tg4	508	28	from	from	IN
cord-310847-63gh2tg4	508	29	interference	interference	NN
cord-310847-63gh2tg4	508	30	.	.	.
cord-310847-63gh2tg4	509	1	168	168	CD
cord-310847-63gh2tg4	510	1	All	all	DT
cord-310847-63gh2tg4	510	2	artificial	artificial	JJ
cord-310847-63gh2tg4	510	3	fusions	fusion	NNS
cord-310847-63gh2tg4	510	4	used	use	VBN
cord-310847-63gh2tg4	510	5	in	in	IN
cord-310847-63gh2tg4	510	6	our	-PRON-	PRP$
cord-310847-63gh2tg4	510	7	study	study	NN
cord-310847-63gh2tg4	510	8	had	have	VBD
cord-310847-63gh2tg4	510	9	low	low	JJ
cord-310847-63gh2tg4	510	10	sequence	sequence	NN
cord-310847-63gh2tg4	510	11	complexity	complexity	NN
cord-310847-63gh2tg4	510	12	and	and	CC
cord-310847-63gh2tg4	510	13	high	high	JJ
cord-310847-63gh2tg4	510	14	net	net	JJ
cord-310847-63gh2tg4	510	15	charge	charge	NN
cord-310847-63gh2tg4	510	16	,	,	,
cord-310847-63gh2tg4	510	17	but	but	CC
cord-310847-63gh2tg4	510	18	were	be	VBD
cord-310847-63gh2tg4	510	19	diversified	diversify	VBN
cord-310847-63gh2tg4	510	20	using	use	VBG
cord-310847-63gh2tg4	510	21	distinctive	distinctive	JJ
cord-310847-63gh2tg4	510	22	amino	amino	NN
cord-310847-63gh2tg4	510	23	acid	acid	NN
cord-310847-63gh2tg4	510	24	compositions	composition	NNS
cord-310847-63gh2tg4	510	25	and	and	CC
cord-310847-63gh2tg4	510	26	lengths	length	NNS
cord-310847-63gh2tg4	510	27	.	.	.
cord-310847-63gh2tg4	511	1	168	168	CD
cord-310847-63gh2tg4	512	1	Among	among	IN
cord-310847-63gh2tg4	512	2	successful	successful	JJ
cord-310847-63gh2tg4	512	3	solubilizers	solubilizer	NNS
cord-310847-63gh2tg4	512	4	were	be	VBD
cord-310847-63gh2tg4	512	5	artificial	artificial	JJ
cord-310847-63gh2tg4	512	6	EBDs	ebd	NNS
cord-310847-63gh2tg4	512	7	containing	contain	VBG
cord-310847-63gh2tg4	512	8	the	the	DT
cord-310847-63gh2tg4	512	9	most	most	JJS
cord-310847-63gh2tg4	512	10	disorder	disorder	NN
cord-310847-63gh2tg4	512	11	-	-	HYPH
cord-310847-63gh2tg4	512	12	promoting	promote	VBG
cord-310847-63gh2tg4	512	13	residues	residue	NNS
cord-310847-63gh2tg4	512	14	(	(	-LRB-
cord-310847-63gh2tg4	512	15	Glu	Glu	NNP
cord-310847-63gh2tg4	512	16	,	,	,
cord-310847-63gh2tg4	512	17	Pro	Pro	NNP
cord-310847-63gh2tg4	512	18	,	,	,
cord-310847-63gh2tg4	512	19	Gln	Gln	NNP
cord-310847-63gh2tg4	512	20	and	and	CC
cord-310847-63gh2tg4	512	21	Ser	Ser	NNP
cord-310847-63gh2tg4	512	22	)	)	-RRB-
cord-310847-63gh2tg4	512	23	in	in	IN
cord-310847-63gh2tg4	512	24	the	the	DT
cord-310847-63gh2tg4	512	25	proportion	proportion	NN
cord-310847-63gh2tg4	512	26	Glu	Glu	NNP
cord-310847-63gh2tg4	512	27	:	:	:
cord-310847-63gh2tg4	513	1	Pro	pro	JJ
cord-310847-63gh2tg4	513	2	:	:	:
cord-310847-63gh2tg4	514	1	Gln	Gln	NNP
cord-310847-63gh2tg4	514	2	:	:	:
cord-310847-63gh2tg4	514	3	Ser	Ser	NNP
cord-310847-63gh2tg4	514	4	=	=	SYM
cord-310847-63gh2tg4	514	5	2:2:1:1	2:2:1:1	CD
cord-310847-63gh2tg4	514	6	;	;	:
cord-310847-63gh2tg4	514	7	i.e.	i.e.	FW
cord-310847-63gh2tg4	514	8	,	,	,
cord-310847-63gh2tg4	514	9	sequences	sequence	NNS
cord-310847-63gh2tg4	514	10	containing	contain	VBG
cord-310847-63gh2tg4	514	11	>	>	SYM
cord-310847-63gh2tg4	514	12	33	33	CD
cord-310847-63gh2tg4	514	13	%	%	NN
cord-310847-63gh2tg4	514	14	glutamic	glutamic	NN
cord-310847-63gh2tg4	514	15	acids	acid	NNS
cord-310847-63gh2tg4	514	16	.	.	.
cord-310847-63gh2tg4	515	1	168	168	CD
cord-310847-63gh2tg4	516	1	Therefore	therefore	RB
cord-310847-63gh2tg4	516	2	,	,	,
cord-310847-63gh2tg4	516	3	it	-PRON-	PRP
cord-310847-63gh2tg4	516	4	seems	seem	VBZ
cord-310847-63gh2tg4	516	5	that	that	IN
cord-310847-63gh2tg4	516	6	glutamic	glutamic	NN
cord-310847-63gh2tg4	516	7	acid	acid	NN
cord-310847-63gh2tg4	516	8	is	be	VBZ
cord-310847-63gh2tg4	516	9	crucial	crucial	JJ
cord-310847-63gh2tg4	516	10	for	for	IN
cord-310847-63gh2tg4	516	11	the	the	DT
cord-310847-63gh2tg4	516	12	successful	successful	JJ
cord-310847-63gh2tg4	516	13	function	function	NN
cord-310847-63gh2tg4	516	14	of	of	IN
cord-310847-63gh2tg4	516	15	EBD	EBD	NNP
cord-310847-63gh2tg4	516	16	-	-	HYPH
cord-310847-63gh2tg4	516	17	containing	contain	VBG
cord-310847-63gh2tg4	516	18	proteins	protein	NNS
cord-310847-63gh2tg4	516	19	.	.	.
cord-310847-63gh2tg4	517	1	Glutamic	glutamic	NN
cord-310847-63gh2tg4	517	2	acids	acid	NNS
cord-310847-63gh2tg4	517	3	in	in	IN
cord-310847-63gh2tg4	517	4	intrinsically	intrinsically	RB
cord-310847-63gh2tg4	517	5	disordered	disordered	JJ
cord-310847-63gh2tg4	517	6	chaperones	chaperone	NNS
cord-310847-63gh2tg4	517	7	.	.	.
cord-310847-63gh2tg4	518	1	The	the	DT
cord-310847-63gh2tg4	518	2	high	high	JJ
cord-310847-63gh2tg4	518	3	content	content	NN
cord-310847-63gh2tg4	518	4	of	of	IN
cord-310847-63gh2tg4	518	5	glutamic	glutamic	JJ
cord-310847-63gh2tg4	518	6	acids	acid	NNS
cord-310847-63gh2tg4	518	7	in	in	IN
cord-310847-63gh2tg4	518	8	artificial	artificial	JJ
cord-310847-63gh2tg4	518	9	EBDs	ebd	NNS
cord-310847-63gh2tg4	518	10	designed	design	VBN
cord-310847-63gh2tg4	518	11	as	as	IN
cord-310847-63gh2tg4	518	12	solubilization	solubilization	NN
cord-310847-63gh2tg4	518	13	means	means	NNP
cord-310847-63gh2tg4	518	14	was	be	VBD
cord-310847-63gh2tg4	518	15	chosen	choose	VBN
cord-310847-63gh2tg4	518	16	because	because	IN
cord-310847-63gh2tg4	518	17	of	of	IN
cord-310847-63gh2tg4	518	18	the	the	DT
cord-310847-63gh2tg4	518	19	earlier	early	JJR
cord-310847-63gh2tg4	518	20	observation	observation	NN
cord-310847-63gh2tg4	518	21	that	that	IN
cord-310847-63gh2tg4	518	22	proteins	protein	NNS
cord-310847-63gh2tg4	518	23	with	with	IN
cord-310847-63gh2tg4	518	24	high	high	JJ
cord-310847-63gh2tg4	518	25	net	net	JJ
cord-310847-63gh2tg4	518	26	charge	charge	NN
cord-310847-63gh2tg4	518	27	densities	density	NNS
cord-310847-63gh2tg4	518	28	can	can	MD
cord-310847-63gh2tg4	518	29	function	function	VB
cord-310847-63gh2tg4	518	30	as	as	IN
cord-310847-63gh2tg4	518	31	effective	effective	JJ
cord-310847-63gh2tg4	518	32	intra	intra	JJ
cord-310847-63gh2tg4	518	33	-	-	JJ
cord-310847-63gh2tg4	518	34	and	and	CC
cord-310847-63gh2tg4	518	35	intermolecular	intermolecular	JJ
cord-310847-63gh2tg4	518	36	chaperones	chaperone	NNS
cord-310847-63gh2tg4	518	37	.	.	.
cord-310847-63gh2tg4	519	1	169	169	CD
cord-310847-63gh2tg4	519	2	-	-	SYM
cord-310847-63gh2tg4	519	3	172	172	CD
cord-310847-63gh2tg4	520	1	For	for	IN
cord-310847-63gh2tg4	520	2	example	example	NN
cord-310847-63gh2tg4	520	3	,	,	,
cord-310847-63gh2tg4	520	4	polyglutamate	polyglutamate	NNP
cord-310847-63gh2tg4	520	5	among	among	IN
cord-310847-63gh2tg4	520	6	other	other	JJ
cord-310847-63gh2tg4	520	7	polyanions	polyanion	NNS
cord-310847-63gh2tg4	520	8	was	be	VBD
cord-310847-63gh2tg4	520	9	shown	show	VBN
cord-310847-63gh2tg4	520	10	to	to	TO
cord-310847-63gh2tg4	520	11	act	act	VB
cord-310847-63gh2tg4	520	12	as	as	IN
cord-310847-63gh2tg4	520	13	a	a	DT
cord-310847-63gh2tg4	520	14	chaperone	chaperone	NN
cord-310847-63gh2tg4	520	15	and	and	CC
cord-310847-63gh2tg4	520	16	to	to	TO
cord-310847-63gh2tg4	520	17	accelerate	accelerate	VB
cord-310847-63gh2tg4	520	18	the	the	DT
cord-310847-63gh2tg4	520	19	in	in	FW
cord-310847-63gh2tg4	520	20	vitro	vitro	FW
cord-310847-63gh2tg4	520	21	refolding	refolde	VBG
cord-310847-63gh2tg4	520	22	of	of	IN
cord-310847-63gh2tg4	520	23	the	the	DT
cord-310847-63gh2tg4	520	24	Arc	Arc	NNP
cord-310847-63gh2tg4	520	25	repressor	repressor	NN
cord-310847-63gh2tg4	520	26	protein	protein	NN
cord-310847-63gh2tg4	520	27	.	.	.
cord-310847-63gh2tg4	521	1	173	173	CD
cord-310847-63gh2tg4	521	2	Small	small	JJ
cord-310847-63gh2tg4	521	3	heat	heat	NN
cord-310847-63gh2tg4	521	4	shock	shock	NN
cord-310847-63gh2tg4	521	5	proteins	protein	NNS
cord-310847-63gh2tg4	521	6	(	(	-LRB-
cord-310847-63gh2tg4	521	7	HSPs	hsp	NNS
cord-310847-63gh2tg4	521	8	)	)	-RRB-
cord-310847-63gh2tg4	521	9	have	have	VBP
cord-310847-63gh2tg4	521	10	flexible	flexible	JJ
cord-310847-63gh2tg4	521	11	C	c	NN
cord-310847-63gh2tg4	521	12	-	-	HYPH
cord-310847-63gh2tg4	521	13	terminal	terminal	NN
cord-310847-63gh2tg4	521	14	extensions	extension	NNS
cord-310847-63gh2tg4	521	15	that	that	WDT
cord-310847-63gh2tg4	521	16	,	,	,
cord-310847-63gh2tg4	521	17	although	although	IN
cord-310847-63gh2tg4	521	18	variable	variable	NN
cord-310847-63gh2tg4	521	19	in	in	IN
cord-310847-63gh2tg4	521	20	length	length	NN
cord-310847-63gh2tg4	521	21	and	and	CC
cord-310847-63gh2tg4	521	22	sequence	sequence	NN
cord-310847-63gh2tg4	521	23	,	,	,
cord-310847-63gh2tg4	521	24	are	be	VBP
cord-310847-63gh2tg4	521	25	rich	rich	JJ
cord-310847-63gh2tg4	521	26	in	in	IN
cord-310847-63gh2tg4	521	27	acidic	acidic	JJ
cord-310847-63gh2tg4	521	28	amino	amino	NN
cord-310847-63gh2tg4	521	29	acids	acid	NNS
cord-310847-63gh2tg4	521	30	.	.	.
cord-310847-63gh2tg4	522	1	169	169	CD
cord-310847-63gh2tg4	523	1	The	the	DT
cord-310847-63gh2tg4	523	2	sHSP	shsp	NN
cord-310847-63gh2tg4	523	3	α	α	NNP
cord-310847-63gh2tg4	523	4	-	-	HYPH
cord-310847-63gh2tg4	523	5	crystallin	crystallin	NNP
cord-310847-63gh2tg4	523	6	can	can	MD
cord-310847-63gh2tg4	523	7	act	act	VB
cord-310847-63gh2tg4	523	8	as	as	IN
cord-310847-63gh2tg4	523	9	a	a	DT
cord-310847-63gh2tg4	523	10	chaperone	chaperone	NN
cord-310847-63gh2tg4	523	11	on	on	IN
cord-310847-63gh2tg4	523	12	the	the	DT
cord-310847-63gh2tg4	523	13	fibroblast	fibroblast	NN
cord-310847-63gh2tg4	523	14	growth	growth	NN
cord-310847-63gh2tg4	523	15	factor	factor	NN
cord-310847-63gh2tg4	523	16	1	1	CD
cord-310847-63gh2tg4	523	17	(	(	-LRB-
cord-310847-63gh2tg4	523	18	FGF-1	FGF-1	NNP
cord-310847-63gh2tg4	523	19	)	)	-RRB-
cord-310847-63gh2tg4	523	20	,	,	,
cord-310847-63gh2tg4	523	21	and	and	CC
cord-310847-63gh2tg4	523	22	this	this	DT
cord-310847-63gh2tg4	523	23	chaperone	chaperone	NN
cord-310847-63gh2tg4	523	24	action	action	NN
cord-310847-63gh2tg4	523	25	is	be	VBZ
cord-310847-63gh2tg4	523	26	mediated	mediate	VBN
cord-310847-63gh2tg4	523	27	by	by	IN
cord-310847-63gh2tg4	523	28	electrostatic	electrostatic	JJ
cord-310847-63gh2tg4	523	29	interactions	interaction	NNS
cord-310847-63gh2tg4	523	30	between	between	IN
cord-310847-63gh2tg4	523	31	the	the	DT
cord-310847-63gh2tg4	523	32	basic	basic	JJ
cord-310847-63gh2tg4	523	33	regions	region	NNS
cord-310847-63gh2tg4	523	34	of	of	IN
cord-310847-63gh2tg4	523	35	the	the	DT
cord-310847-63gh2tg4	523	36	growth	growth	NN
cord-310847-63gh2tg4	523	37	factor	factor	NN
cord-310847-63gh2tg4	523	38	and	and	CC
cord-310847-63gh2tg4	523	39	acidic	acidic	JJ
cord-310847-63gh2tg4	523	40	regions	region	NNS
cord-310847-63gh2tg4	523	41	of	of	IN
cord-310847-63gh2tg4	523	42	α	α	NN
cord-310847-63gh2tg4	523	43	-	-	HYPH
cord-310847-63gh2tg4	523	44	crystallin	crystallin	NNP
cord-310847-63gh2tg4	523	45	.	.	.
cord-310847-63gh2tg4	524	1	174	174	CD
cord-310847-63gh2tg4	525	1	Nucleolar	Nucleolar	NNP
cord-310847-63gh2tg4	525	2	chaperone	chaperone	NN
cord-310847-63gh2tg4	525	3	B23	B23	NNP
cord-310847-63gh2tg4	525	4	(	(	-LRB-
cord-310847-63gh2tg4	525	5	294	294	CD
cord-310847-63gh2tg4	525	6	residues	residue	NNS
cord-310847-63gh2tg4	525	7	,	,	,
cord-310847-63gh2tg4	525	8	31	31	CD
cord-310847-63gh2tg4	525	9	of	of	IN
cord-310847-63gh2tg4	525	10	which	which	WDT
cord-310847-63gh2tg4	525	11	are	be	VBP
cord-310847-63gh2tg4	525	12	glutamic	glutamic	JJ
cord-310847-63gh2tg4	525	13	acids	acid	NNS
cord-310847-63gh2tg4	525	14	)	)	-RRB-
cord-310847-63gh2tg4	525	15	has	have	VBZ
cord-310847-63gh2tg4	525	16	two	two	CD
cord-310847-63gh2tg4	525	17	acidic	acidic	JJ
cord-310847-63gh2tg4	525	18	regions	region	NNS
cord-310847-63gh2tg4	525	19	(	(	-LRB-
cord-310847-63gh2tg4	525	20	residues	residue	NNS
cord-310847-63gh2tg4	525	21	120	120	CD
cord-310847-63gh2tg4	525	22	-	-	SYM
cord-310847-63gh2tg4	525	23	132	132	CD
cord-310847-63gh2tg4	525	24	and	and	CC
cord-310847-63gh2tg4	525	25	161	161	CD
cord-310847-63gh2tg4	525	26	-	-	SYM
cord-310847-63gh2tg4	525	27	188	188	CD
cord-310847-63gh2tg4	525	28	)	)	-RRB-
cord-310847-63gh2tg4	525	29	that	that	WDT
cord-310847-63gh2tg4	525	30	contain	contain	VBP
cord-310847-63gh2tg4	525	31	8	8	CD
cord-310847-63gh2tg4	525	32	glutamic	glutamic	NN
cord-310847-63gh2tg4	525	33	residues	residue	NNS
cord-310847-63gh2tg4	525	34	each	each	DT
cord-310847-63gh2tg4	526	1	and	and	CC
cord-310847-63gh2tg4	526	2	that	that	DT
cord-310847-63gh2tg4	526	3	are	be	VBP
cord-310847-63gh2tg4	526	4	necessary	necessary	JJ
cord-310847-63gh2tg4	526	5	for	for	IN
cord-310847-63gh2tg4	526	6	the	the	DT
cord-310847-63gh2tg4	526	7	B23	B23	NNP
cord-310847-63gh2tg4	526	8	chaperone	chaperone	NN
cord-310847-63gh2tg4	526	9	-	-	HYPH
cord-310847-63gh2tg4	526	10	like	like	JJ
cord-310847-63gh2tg4	526	11	activity	activity	NN
cord-310847-63gh2tg4	526	12	.	.	.
cord-310847-63gh2tg4	527	1	175	175	CD
cord-310847-63gh2tg4	528	1	Tubulin	Tubulin	NNP
cord-310847-63gh2tg4	528	2	has	have	VBZ
cord-310847-63gh2tg4	528	3	chaperone	chaperone	NN
cord-310847-63gh2tg4	528	4	-	-	HYPH
cord-310847-63gh2tg4	528	5	like	like	JJ
cord-310847-63gh2tg4	528	6	activity	activity	NN
cord-310847-63gh2tg4	528	7	being	be	VBG
cord-310847-63gh2tg4	528	8	able	able	JJ
cord-310847-63gh2tg4	528	9	to	to	TO
cord-310847-63gh2tg4	528	10	suppress	suppress	VB
cord-310847-63gh2tg4	528	11	the	the	DT
cord-310847-63gh2tg4	528	12	aggregation	aggregation	NN
cord-310847-63gh2tg4	528	13	of	of	IN
cord-310847-63gh2tg4	528	14	soluble	soluble	JJ
cord-310847-63gh2tg4	528	15	lens	lens	NN
cord-310847-63gh2tg4	528	16	proteins	protein	NNS
cord-310847-63gh2tg4	528	17	,	,	,
cord-310847-63gh2tg4	528	18	equine	equine	JJ
cord-310847-63gh2tg4	528	19	liver	liver	NN
cord-310847-63gh2tg4	528	20	alcohol	alcohol	NN
cord-310847-63gh2tg4	528	21	dehydrogenase	dehydrogenase	NN
cord-310847-63gh2tg4	528	22	,	,	,
cord-310847-63gh2tg4	528	23	malic	malic	NN
cord-310847-63gh2tg4	528	24	dehydrogenase	dehydrogenase	NN
cord-310847-63gh2tg4	528	25	and	and	CC
cord-310847-63gh2tg4	528	26	insulin	insulin	NN
cord-310847-63gh2tg4	528	27	,	,	,
cord-310847-63gh2tg4	528	28	but	but	CC
cord-310847-63gh2tg4	528	29	only	only	RB
cord-310847-63gh2tg4	528	30	if	if	IN
cord-310847-63gh2tg4	528	31	its	-PRON-	PRP$
cord-310847-63gh2tg4	528	32	acidic	acidic	JJ
cord-310847-63gh2tg4	528	33	C	c	NN
cord-310847-63gh2tg4	528	34	-	-	HYPH
cord-310847-63gh2tg4	528	35	terminus	terminus	NN
cord-310847-63gh2tg4	528	36	(	(	-LRB-
cord-310847-63gh2tg4	528	37	that	that	DT
cord-310847-63gh2tg4	528	38	contains	contain	VBZ
cord-310847-63gh2tg4	528	39	39	39	CD
cord-310847-63gh2tg4	528	40	%	%	NN
cord-310847-63gh2tg4	528	41	and	and	CC
cord-310847-63gh2tg4	528	42	33.3	33.3	CD
cord-310847-63gh2tg4	528	43	%	%	NN
cord-310847-63gh2tg4	528	44	of	of	IN
cord-310847-63gh2tg4	528	45	glutamic	glutamic	NN
cord-310847-63gh2tg4	528	46	acid	acid	NN
cord-310847-63gh2tg4	528	47	residuess	residuess	NN
cord-310847-63gh2tg4	528	48	in	in	IN
cord-310847-63gh2tg4	528	49	the	the	DT
cord-310847-63gh2tg4	528	50	porcine	porcine	JJ
cord-310847-63gh2tg4	528	51	αand	αand	NN
cord-310847-63gh2tg4	528	52	β	β	NN
cord-310847-63gh2tg4	528	53	-	-	HYPH
cord-310847-63gh2tg4	528	54	tubulins	tubulins	NNP
cord-310847-63gh2tg4	528	55	,	,	,
cord-310847-63gh2tg4	528	56	respectively	respectively	RB
cord-310847-63gh2tg4	528	57	)	)	-RRB-
cord-310847-63gh2tg4	528	58	was	be	VBD
cord-310847-63gh2tg4	528	59	intact	intact	JJ
cord-310847-63gh2tg4	528	60	.	.	.
cord-310847-63gh2tg4	529	1	[	[	-LRB-
cord-310847-63gh2tg4	529	2	176	176	CD
cord-310847-63gh2tg4	529	3	]	]	-RRB-
cord-310847-63gh2tg4	529	4	[	[	-LRB-
cord-310847-63gh2tg4	529	5	177	177	CD
cord-310847-63gh2tg4	529	6	]	]	-RRB-
cord-310847-63gh2tg4	529	7	[	[	-LRB-
cord-310847-63gh2tg4	529	8	178	178	CD
cord-310847-63gh2tg4	529	9	]	]	-RRB-
cord-310847-63gh2tg4	530	1	Many	many	JJ
cord-310847-63gh2tg4	530	2	polyanionic	polyanionic	JJ
cord-310847-63gh2tg4	530	3	propeptides	propeptide	NNS
cord-310847-63gh2tg4	530	4	were	be	VBD
cord-310847-63gh2tg4	530	5	shown	show	VBN
cord-310847-63gh2tg4	530	6	to	to	TO
cord-310847-63gh2tg4	530	7	serve	serve	VB
cord-310847-63gh2tg4	530	8	as	as	IN
cord-310847-63gh2tg4	530	9	intramolecular	intramolecular	JJ
cord-310847-63gh2tg4	530	10	chaperones	chaperone	NNS
cord-310847-63gh2tg4	530	11	to	to	TO
cord-310847-63gh2tg4	530	12	aid	aid	VB
cord-310847-63gh2tg4	530	13	folding	folding	NN
cord-310847-63gh2tg4	530	14	of	of	IN
cord-310847-63gh2tg4	530	15	the	the	DT
cord-310847-63gh2tg4	530	16	respective	respective	JJ
cord-310847-63gh2tg4	530	17	proteins	protein	NNS
cord-310847-63gh2tg4	530	18	.	.	.
cord-310847-63gh2tg4	531	1	[	[	-LRB-
cord-310847-63gh2tg4	531	2	179	179	CD
cord-310847-63gh2tg4	531	3	]	]	-RRB-
cord-310847-63gh2tg4	531	4	[	[	-LRB-
cord-310847-63gh2tg4	531	5	180	180	CD
cord-310847-63gh2tg4	531	6	]	]	-RRB-
cord-310847-63gh2tg4	531	7	[	[	-LRB-
cord-310847-63gh2tg4	531	8	181	181	CD
cord-310847-63gh2tg4	531	9	]	]	-RRB-
cord-310847-63gh2tg4	532	1	[	[	-LRB-
cord-310847-63gh2tg4	532	2	182	182	CD
cord-310847-63gh2tg4	532	3	]	]	-RRB-
cord-310847-63gh2tg4	533	1	For	for	IN
cord-310847-63gh2tg4	533	2	example	example	NN
cord-310847-63gh2tg4	533	3	,	,	,
cord-310847-63gh2tg4	533	4	propeptides	propeptides	NNP
cord-310847-63gh2tg4	533	5	of	of	IN
cord-310847-63gh2tg4	533	6	human	human	JJ
cord-310847-63gh2tg4	533	7	neutrophil	neutrophil	NN
cord-310847-63gh2tg4	533	8	defensins	defensin	NNS
cord-310847-63gh2tg4	533	9	contain	contain	VBP
cord-310847-63gh2tg4	533	10	up	up	IN
cord-310847-63gh2tg4	533	11	to	to	TO
cord-310847-63gh2tg4	533	12	15.8	15.8	CD
cord-310847-63gh2tg4	533	13	%	%	NN
cord-310847-63gh2tg4	533	14	glutamic	glutamic	NN
cord-310847-63gh2tg4	533	15	acids	acid	NNS
cord-310847-63gh2tg4	533	16	.	.	.
cord-310847-63gh2tg4	534	1	Also	also	RB
cord-310847-63gh2tg4	534	2	,	,	,
cord-310847-63gh2tg4	534	3	the	the	DT
cord-310847-63gh2tg4	534	4	C	C	NNP
cord-310847-63gh2tg4	534	5	-	-	HYPH
cord-310847-63gh2tg4	534	6	terminal	terminal	NN
cord-310847-63gh2tg4	534	7	solubilizing	solubilizing	NN
cord-310847-63gh2tg4	534	8	domain	domain	NN
cord-310847-63gh2tg4	534	9	of	of	IN
cord-310847-63gh2tg4	534	10	human	human	JJ
cord-310847-63gh2tg4	534	11	α	α	NNP
cord-310847-63gh2tg4	534	12	-	-	HYPH
cord-310847-63gh2tg4	534	13	synuclein	synuclein	NNP
cord-310847-63gh2tg4	534	14	(	(	-LRB-
cord-310847-63gh2tg4	534	15	residues	residue	NNS
cord-310847-63gh2tg4	534	16	100	100	CD
cord-310847-63gh2tg4	534	17	-	-	SYM
cord-310847-63gh2tg4	534	18	140	140	CD
cord-310847-63gh2tg4	534	19	)	)	-RRB-
cord-310847-63gh2tg4	534	20	contains	contain	VBZ
cord-310847-63gh2tg4	534	21	24.4	24.4	CD
cord-310847-63gh2tg4	534	22	%	%	NN
cord-310847-63gh2tg4	534	23	glutamates	glutamate	NNS
cord-310847-63gh2tg4	534	24	,	,	,
cord-310847-63gh2tg4	534	25	whereas	whereas	IN
cord-310847-63gh2tg4	534	26	ERD10	erd10	NN
cord-310847-63gh2tg4	534	27	(	(	-LRB-
cord-310847-63gh2tg4	534	28	260	260	CD
cord-310847-63gh2tg4	534	29	residues	residue	NNS
cord-310847-63gh2tg4	534	30	)	)	-RRB-
cord-310847-63gh2tg4	534	31	and	and	CC
cord-310847-63gh2tg4	534	32	ERD14	ERD14	NNP
cord-310847-63gh2tg4	534	33	dehydrins	dehydrin	NNS
cord-310847-63gh2tg4	534	34	(	(	-LRB-
cord-310847-63gh2tg4	534	35	185	185	CD
cord-310847-63gh2tg4	534	36	residues	residue	NNS
cord-310847-63gh2tg4	534	37	)	)	-RRB-
cord-310847-63gh2tg4	534	38	from	from	IN
cord-310847-63gh2tg4	534	39	Arabidopsis	Arabidopsis	NNP
cord-310847-63gh2tg4	534	40	thaliana	thaliana	NNS
cord-310847-63gh2tg4	534	41	contain	contain	VBP
cord-310847-63gh2tg4	534	42	19.6	19.6	CD
cord-310847-63gh2tg4	534	43	%	%	NN
cord-310847-63gh2tg4	534	44	and	and	CC
cord-310847-63gh2tg4	534	45	21.1	21.1	CD
cord-310847-63gh2tg4	534	46	%	%	NN
cord-310847-63gh2tg4	534	47	glutamic	glutamic	NN
cord-310847-63gh2tg4	534	48	acids	acid	NNS
cord-310847-63gh2tg4	534	49	respectively	respectively	RB
cord-310847-63gh2tg4	534	50	.	.	.
cord-310847-63gh2tg4	535	1	Some	some	DT
cord-310847-63gh2tg4	535	2	functions	function	NNS
cord-310847-63gh2tg4	535	3	of	of	IN
cord-310847-63gh2tg4	535	4	glutamate	glutamate	NN
cord-310847-63gh2tg4	535	5	-	-	HYPH
cord-310847-63gh2tg4	535	6	rich	rich	JJ
cord-310847-63gh2tg4	535	7	peptides	peptide	NNS
cord-310847-63gh2tg4	535	8	.	.	.
cord-310847-63gh2tg4	536	1	This	this	DT
cord-310847-63gh2tg4	536	2	section	section	NN
cord-310847-63gh2tg4	536	3	presents	present	VBZ
cord-310847-63gh2tg4	536	4	several	several	JJ
cord-310847-63gh2tg4	536	5	illustrative	illustrative	JJ
cord-310847-63gh2tg4	536	6	examples	example	NNS
cord-310847-63gh2tg4	536	7	of	of	IN
cord-310847-63gh2tg4	536	8	important	important	JJ
cord-310847-63gh2tg4	536	9	biological	biological	JJ
cord-310847-63gh2tg4	536	10	functions	function	NNS
cord-310847-63gh2tg4	536	11	attributed	attribute	VBN
cord-310847-63gh2tg4	536	12	to	to	IN
cord-310847-63gh2tg4	536	13	glutamate	glutamate	NN
cord-310847-63gh2tg4	536	14	-	-	HYPH
cord-310847-63gh2tg4	536	15	rich	rich	JJ
cord-310847-63gh2tg4	536	16	peptides	peptide	NNS
cord-310847-63gh2tg4	536	17	.	.	.
cord-310847-63gh2tg4	537	1	Phytochelatins	Phytochelatins	NNP
cord-310847-63gh2tg4	537	2	.	.	.
cord-310847-63gh2tg4	538	1	Heavy	heavy	JJ
cord-310847-63gh2tg4	538	2	metal	metal	NN
cord-310847-63gh2tg4	538	3	detoxification	detoxification	NN
cord-310847-63gh2tg4	538	4	in	in	IN
cord-310847-63gh2tg4	538	5	higher	high	JJR
cord-310847-63gh2tg4	538	6	plants	plant	NNS
cord-310847-63gh2tg4	538	7	is	be	VBZ
cord-310847-63gh2tg4	538	8	dependent	dependent	JJ
cord-310847-63gh2tg4	538	9	on	on	IN
cord-310847-63gh2tg4	538	10	a	a	DT
cord-310847-63gh2tg4	538	11	set	set	NN
cord-310847-63gh2tg4	538	12	of	of	IN
cord-310847-63gh2tg4	538	13	heavy	heavy	JJ
cord-310847-63gh2tg4	538	14	-	-	HYPH
cord-310847-63gh2tg4	538	15	metal	metal	NN
cord-310847-63gh2tg4	538	16	-	-	HYPH
cord-310847-63gh2tg4	538	17	complexing	complexe	VBG
cord-310847-63gh2tg4	538	18	peptides	peptide	NNS
cord-310847-63gh2tg4	538	19	,	,	,
cord-310847-63gh2tg4	538	20	phytochelatins	phytochelatin	NNS
cord-310847-63gh2tg4	538	21	,	,	,
cord-310847-63gh2tg4	538	22	with	with	IN
cord-310847-63gh2tg4	538	23	structure	structure	NN
cord-310847-63gh2tg4	538	24	of	of	IN
cord-310847-63gh2tg4	538	25	(	(	-LRB-
cord-310847-63gh2tg4	538	26	γ	γ	NN
cord-310847-63gh2tg4	538	27	-	-	HYPH
cord-310847-63gh2tg4	538	28	glutamic	glutamic	NN
cord-310847-63gh2tg4	538	29	acid	acid	NN
cord-310847-63gh2tg4	538	30	-	-	HYPH
cord-310847-63gh2tg4	538	31	cysteine	cysteine	NN
cord-310847-63gh2tg4	538	32	)	)	-RRB-
cord-310847-63gh2tg4	538	33	n	n	NN
cord-310847-63gh2tg4	538	34	-glycine	-glycine	CD
cord-310847-63gh2tg4	539	1	(	(	-LRB-
cord-310847-63gh2tg4	539	2	n	n	NN
cord-310847-63gh2tg4	539	3	=	=	SYM
cord-310847-63gh2tg4	539	4	2	2	CD
cord-310847-63gh2tg4	539	5	-	-	SYM
cord-310847-63gh2tg4	539	6	11	11	CD
cord-310847-63gh2tg4	539	7	)	)	-RRB-
cord-310847-63gh2tg4	540	1	[	[	-LRB-
cord-310847-63gh2tg4	540	2	(	(	-LRB-
cord-310847-63gh2tg4	540	3	γ	γ	NN
cord-310847-63gh2tg4	540	4	-	-	HYPH
cord-310847-63gh2tg4	540	5	Glu	Glu	NNP
cord-310847-63gh2tg4	540	6	-	-	HYPH
cord-310847-63gh2tg4	540	7	Cys	Cys	NNP
cord-310847-63gh2tg4	540	8	)	)	-RRB-
cord-310847-63gh2tg4	540	9	n	n	NNP
cord-310847-63gh2tg4	540	10	-Gly	-Gly	NNP
cord-310847-63gh2tg4	540	11	]	]	-RRB-
cord-310847-63gh2tg4	540	12	.	.	.
cord-310847-63gh2tg4	541	1	183	183	CD
cord-310847-63gh2tg4	542	1	The	the	DT
cord-310847-63gh2tg4	542	2	longest	long	JJS
cord-310847-63gh2tg4	542	3	of	of	IN
cord-310847-63gh2tg4	542	4	these	these	DT
cord-310847-63gh2tg4	542	5	peptides	peptide	NNS
cord-310847-63gh2tg4	542	6	possesses	possess	VBZ
cord-310847-63gh2tg4	542	7	a	a	DT
cord-310847-63gh2tg4	542	8	molecular	molecular	JJ
cord-310847-63gh2tg4	542	9	mass	mass	NN
cord-310847-63gh2tg4	542	10	of	of	IN
cord-310847-63gh2tg4	542	11	2.6	2.6	CD
cord-310847-63gh2tg4	542	12	kDa	kDa	NNPS
cord-310847-63gh2tg4	542	13	,	,	,
cord-310847-63gh2tg4	542	14	a	a	DT
cord-310847-63gh2tg4	542	15	pI	pI	NNP
cord-310847-63gh2tg4	542	16	3.26	3.26	CD
cord-310847-63gh2tg4	542	17	and	and	CC
cord-310847-63gh2tg4	542	18	a	a	DT
cord-310847-63gh2tg4	542	19	net	net	JJ
cord-310847-63gh2tg4	542	20	charge	charge	NN
cord-310847-63gh2tg4	542	21	of	of	IN
cord-310847-63gh2tg4	542	22	−11	−11	NNP
cord-310847-63gh2tg4	542	23	.	.	.
cord-310847-63gh2tg4	543	1	These	these	DT
cord-310847-63gh2tg4	543	2	peptides	peptide	NNS
cord-310847-63gh2tg4	543	3	are	be	VBP
cord-310847-63gh2tg4	543	4	induced	induce	VBN
cord-310847-63gh2tg4	543	5	by	by	IN
cord-310847-63gh2tg4	543	6	the	the	DT
cord-310847-63gh2tg4	543	7	exposure	exposure	NN
cord-310847-63gh2tg4	543	8	of	of	IN
cord-310847-63gh2tg4	543	9	plants	plant	NNS
cord-310847-63gh2tg4	543	10	to	to	IN
cord-310847-63gh2tg4	543	11	ARGLU1	ARGLU1	NNP
cord-310847-63gh2tg4	543	12	.	.	.
cord-310847-63gh2tg4	544	1	Transcriptional	Transcriptional	NNP
cord-310847-63gh2tg4	544	2	activators	activator	NNS
cord-310847-63gh2tg4	544	3	and	and	CC
cord-310847-63gh2tg4	544	4	RNA	RNA	NNP
cord-310847-63gh2tg4	544	5	polymerase	polymerase	NN
cord-310847-63gh2tg4	544	6	II	II	NNP
cord-310847-63gh2tg4	544	7	are	be	VBP
cord-310847-63gh2tg4	544	8	bridged	bridge	VBN
cord-310847-63gh2tg4	544	9	via	via	IN
cord-310847-63gh2tg4	544	10	the	the	DT
cord-310847-63gh2tg4	544	11	central	central	JJ
cord-310847-63gh2tg4	544	12	transcriptional	transcriptional	JJ
cord-310847-63gh2tg4	544	13	coactivator	coactivator	NN
cord-310847-63gh2tg4	544	14	complex	complex	NN
cord-310847-63gh2tg4	544	15	,	,	,
cord-310847-63gh2tg4	544	16	the	the	DT
cord-310847-63gh2tg4	544	17	Mediator	Mediator	NNP
cord-310847-63gh2tg4	544	18	complex	complex	NN
cord-310847-63gh2tg4	544	19	.	.	.
cord-310847-63gh2tg4	545	1	It	-PRON-	PRP
cord-310847-63gh2tg4	545	2	has	have	VBZ
cord-310847-63gh2tg4	545	3	been	be	VBN
cord-310847-63gh2tg4	545	4	recently	recently	RB
cord-310847-63gh2tg4	545	5	shown	show	VBN
cord-310847-63gh2tg4	545	6	that	that	IN
cord-310847-63gh2tg4	545	7	the	the	DT
cord-310847-63gh2tg4	545	8	arginine	arginine	NN
cord-310847-63gh2tg4	545	9	and	and	CC
cord-310847-63gh2tg4	545	10	glutamate	glutamate	NN
cord-310847-63gh2tg4	545	11	rich	rich	JJ
cord-310847-63gh2tg4	545	12	1	1	CD
cord-310847-63gh2tg4	545	13	protein	protein	NN
cord-310847-63gh2tg4	545	14	(	(	-LRB-
cord-310847-63gh2tg4	545	15	ARGLU1	ARGLU1	NNP
cord-310847-63gh2tg4	545	16	)	)	-RRB-
cord-310847-63gh2tg4	545	17	colocalizes	colocalizes	NNP
cord-310847-63gh2tg4	545	18	with	with	IN
cord-310847-63gh2tg4	545	19	the	the	DT
cord-310847-63gh2tg4	545	20	Mediator	Mediator	NNP
cord-310847-63gh2tg4	545	21	subunit	subunit	NN
cord-310847-63gh2tg4	545	22	1	1	CD
cord-310847-63gh2tg4	545	23	(	(	-LRB-
cord-310847-63gh2tg4	545	24	MED1	MED1	NNP
cord-310847-63gh2tg4	545	25	)	)	-RRB-
cord-310847-63gh2tg4	545	26	in	in	IN
cord-310847-63gh2tg4	545	27	the	the	DT
cord-310847-63gh2tg4	545	28	nucleus	nucleus	NN
cord-310847-63gh2tg4	545	29	,	,	,
cord-310847-63gh2tg4	545	30	being	be	VBG
cord-310847-63gh2tg4	545	31	in	in	IN
cord-310847-63gh2tg4	545	32	contact	contact	NN
cord-310847-63gh2tg4	545	33	with	with	IN
cord-310847-63gh2tg4	545	34	the	the	DT
cord-310847-63gh2tg4	545	35	far	far	JJ
cord-310847-63gh2tg4	545	36	C	c	NN
cord-310847-63gh2tg4	545	37	-	-	HYPH
cord-310847-63gh2tg4	545	38	terminal	terminal	NN
cord-310847-63gh2tg4	545	39	region	region	NN
cord-310847-63gh2tg4	545	40	of	of	IN
cord-310847-63gh2tg4	545	41	MED1	MED1	NNP
cord-310847-63gh2tg4	545	42	.	.	.
cord-310847-63gh2tg4	546	1	190	190	CD
cord-310847-63gh2tg4	547	1	This	this	DT
cord-310847-63gh2tg4	547	2	ARGLU1-MED1	ARGLU1-MED1	NNP
cord-310847-63gh2tg4	547	3	interaction	interaction	NN
cord-310847-63gh2tg4	547	4	is	be	VBZ
cord-310847-63gh2tg4	547	5	crucial	crucial	JJ
cord-310847-63gh2tg4	547	6	for	for	IN
cord-310847-63gh2tg4	547	7	the	the	DT
cord-310847-63gh2tg4	547	8	estrogen	estrogen	NN
cord-310847-63gh2tg4	547	9	-	-	HYPH
cord-310847-63gh2tg4	547	10	dependent	dependent	JJ
cord-310847-63gh2tg4	547	11	gene	gene	NN
cord-310847-63gh2tg4	547	12	transcription	transcription	NN
cord-310847-63gh2tg4	547	13	and	and	CC
cord-310847-63gh2tg4	547	14	breast	breast	NN
cord-310847-63gh2tg4	547	15	cancer	cancer	NN
cord-310847-63gh2tg4	547	16	cell	cell	NN
cord-310847-63gh2tg4	547	17	growth	growth	NN
cord-310847-63gh2tg4	547	18	.	.	.
cord-310847-63gh2tg4	548	1	190	190	CD
cord-310847-63gh2tg4	548	2	Human	Human	NNP
cord-310847-63gh2tg4	548	3	ARGLU1	ARGLU1	NNP
cord-310847-63gh2tg4	548	4	is	be	VBZ
cord-310847-63gh2tg4	548	5	a	a	DT
cord-310847-63gh2tg4	548	6	270	270	CD
cord-310847-63gh2tg4	548	7	residues	residue	NNS
cord-310847-63gh2tg4	548	8	-	-	HYPH
cord-310847-63gh2tg4	548	9	long	long	JJ
cord-310847-63gh2tg4	548	10	protein	protein	NN
cord-310847-63gh2tg4	548	11	that	that	WDT
cord-310847-63gh2tg4	548	12	contains	contain	VBZ
cord-310847-63gh2tg4	548	13	53	53	CD
cord-310847-63gh2tg4	548	14	arginines	arginine	NNS
cord-310847-63gh2tg4	548	15	and	and	CC
cord-310847-63gh2tg4	548	16	54	54	CD
cord-310847-63gh2tg4	548	17	glutamates	glutamate	NNS
cord-310847-63gh2tg4	548	18	.	.	.
cord-310847-63gh2tg4	549	1	There	there	EX
cord-310847-63gh2tg4	549	2	are	be	VBP
cord-310847-63gh2tg4	549	3	two	two	CD
cord-310847-63gh2tg4	549	4	regions	region	NNS
cord-310847-63gh2tg4	549	5	with	with	IN
cord-310847-63gh2tg4	549	6	significant	significant	JJ
cord-310847-63gh2tg4	549	7	composition	composition	NN
cord-310847-63gh2tg4	549	8	biases	bias	NNS
cord-310847-63gh2tg4	549	9	in	in	IN
cord-310847-63gh2tg4	549	10	this	this	DT
cord-310847-63gh2tg4	549	11	protein	protein	NN
cord-310847-63gh2tg4	549	12	,	,	,
cord-310847-63gh2tg4	549	13	an	an	DT
cord-310847-63gh2tg4	549	14	arginine	arginine	NN
cord-310847-63gh2tg4	549	15	-	-	HYPH
cord-310847-63gh2tg4	549	16	rich	rich	JJ
cord-310847-63gh2tg4	549	17	region	region	NN
cord-310847-63gh2tg4	549	18	(	(	-LRB-
cord-310847-63gh2tg4	549	19	residues	residue	NNS
cord-310847-63gh2tg4	549	20	3	3	CD
cord-310847-63gh2tg4	549	21	-	-	SYM
cord-310847-63gh2tg4	549	22	74	74	CD
cord-310847-63gh2tg4	549	23	)	)	-RRB-
cord-310847-63gh2tg4	549	24	that	that	WDT
cord-310847-63gh2tg4	549	25	contains	contain	VBZ
cord-310847-63gh2tg4	549	26	25	25	CD
cord-310847-63gh2tg4	549	27	arginines	arginine	NNS
cord-310847-63gh2tg4	549	28	and	and	CC
cord-310847-63gh2tg4	549	29	a	a	DT
cord-310847-63gh2tg4	549	30	glutamic	glutamic	NN
cord-310847-63gh2tg4	549	31	acid	acid	NN
cord-310847-63gh2tg4	549	32	-	-	HYPH
cord-310847-63gh2tg4	549	33	rich	rich	JJ
cord-310847-63gh2tg4	549	34	region	region	NN
cord-310847-63gh2tg4	549	35	(	(	-LRB-
cord-310847-63gh2tg4	549	36	residues	residue	NNS
cord-310847-63gh2tg4	549	37	27	27	CD
cord-310847-63gh2tg4	549	38	-	-	HYPH
cord-310847-63gh2tg4	549	39	251	251	CD
cord-310847-63gh2tg4	549	40	)	)	-RRB-
cord-310847-63gh2tg4	549	41	containing	contain	VBG
cord-310847-63gh2tg4	549	42	49	49	CD
cord-310847-63gh2tg4	549	43	glutamic	glutamic	JJ
cord-310847-63gh2tg4	549	44	acids	acid	NNS
cord-310847-63gh2tg4	549	45	.	.	.
cord-310847-63gh2tg4	550	1	PELP1	PELP1	NNP
cord-310847-63gh2tg4	550	2	.	.	.
cord-310847-63gh2tg4	551	1	Proline-	Proline-	NNP
cord-310847-63gh2tg4	551	2	,	,	,
cord-310847-63gh2tg4	552	1	glutamic	glutamic	NNP
cord-310847-63gh2tg4	552	2	acid	acid	NN
cord-310847-63gh2tg4	552	3	-	-	HYPH
cord-310847-63gh2tg4	552	4	and	and	CC
cord-310847-63gh2tg4	552	5	leucine	leucine	NN
cord-310847-63gh2tg4	552	6	-	-	HYPH
cord-310847-63gh2tg4	552	7	rich	rich	JJ
cord-310847-63gh2tg4	552	8	protein-1	protein-1	NNP
cord-310847-63gh2tg4	552	9	(	(	-LRB-
cord-310847-63gh2tg4	552	10	PELP1	PELP1	NNP
cord-310847-63gh2tg4	552	11	)	)	-RRB-
cord-310847-63gh2tg4	552	12	plays	play	VBZ
cord-310847-63gh2tg4	552	13	an	an	DT
cord-310847-63gh2tg4	552	14	important	important	JJ
cord-310847-63gh2tg4	552	15	role	role	NN
cord-310847-63gh2tg4	552	16	in	in	IN
cord-310847-63gh2tg4	552	17	mediation	mediation	NN
cord-310847-63gh2tg4	552	18	of	of	IN
cord-310847-63gh2tg4	552	19	genomic	genomic	JJ
cord-310847-63gh2tg4	552	20	and	and	CC
cord-310847-63gh2tg4	552	21	nongenomic	nongenomic	JJ
cord-310847-63gh2tg4	552	22	signaling	signaling	NN
cord-310847-63gh2tg4	552	23	of	of	IN
cord-310847-63gh2tg4	552	24	β	β	NN
cord-310847-63gh2tg4	552	25	-	-	HYPH
cord-310847-63gh2tg4	552	26	estradiol	estradiol	NNP
cord-310847-63gh2tg4	552	27	.	.	.
cord-310847-63gh2tg4	553	1	191	191	CD
cord-310847-63gh2tg4	554	1	This	this	DT
cord-310847-63gh2tg4	554	2	potential	potential	JJ
cord-310847-63gh2tg4	554	3	protooncogene	protooncogene	JJ
cord-310847-63gh2tg4	554	4	functions	function	NNS
cord-310847-63gh2tg4	554	5	as	as	IN
cord-310847-63gh2tg4	554	6	a	a	DT
cord-310847-63gh2tg4	554	7	co	co	NN
cord-310847-63gh2tg4	554	8	-	-	NN
cord-310847-63gh2tg4	554	9	regulator	regulator	NN
cord-310847-63gh2tg4	554	10	of	of	IN
cord-310847-63gh2tg4	554	11	estrogen	estrogen	NN
cord-310847-63gh2tg4	554	12	receptor	receptor	NN
cord-310847-63gh2tg4	554	13	,	,	,
cord-310847-63gh2tg4	554	14	and	and	CC
cord-310847-63gh2tg4	554	15	expression	expression	NN
cord-310847-63gh2tg4	554	16	of	of	IN
cord-310847-63gh2tg4	554	17	PELP1	PELP1	NNP
cord-310847-63gh2tg4	554	18	is	be	VBZ
cord-310847-63gh2tg4	554	19	deregulated	deregulate	VBN
cord-310847-63gh2tg4	554	20	during	during	IN
cord-310847-63gh2tg4	554	21	breast	breast	NN
cord-310847-63gh2tg4	554	22	cancer	cancer	NN
cord-310847-63gh2tg4	554	23	progression	progression	NN
cord-310847-63gh2tg4	554	24	.	.	.
cord-310847-63gh2tg4	555	1	192	192	CD
cord-310847-63gh2tg4	555	2	PELP1	PELP1	NNP
cord-310847-63gh2tg4	555	3	contains	contain	VBZ
cord-310847-63gh2tg4	555	4	ten	ten	CD
cord-310847-63gh2tg4	555	5	nuclear	nuclear	JJ
cord-310847-63gh2tg4	555	6	receptor	receptor	NN
cord-310847-63gh2tg4	555	7	-	-	HYPH
cord-310847-63gh2tg4	555	8	interacting	interact	VBG
cord-310847-63gh2tg4	555	9	boxes	box	NNS
cord-310847-63gh2tg4	555	10	(	(	-LRB-
cord-310847-63gh2tg4	555	11	LXXLL	LXXLL	NNP
cord-310847-63gh2tg4	555	12	motifs	motif	NNS
cord-310847-63gh2tg4	555	13	)	)	-RRB-
cord-310847-63gh2tg4	555	14	,	,	,
cord-310847-63gh2tg4	555	15	which	which	WDT
cord-310847-63gh2tg4	555	16	allow	allow	VBP
cord-310847-63gh2tg4	555	17	it	-PRON-	PRP
cord-310847-63gh2tg4	555	18	to	to	TO
cord-310847-63gh2tg4	555	19	interact	interact	VB
cord-310847-63gh2tg4	555	20	with	with	IN
cord-310847-63gh2tg4	555	21	estrogen	estrogen	NN
cord-310847-63gh2tg4	555	22	receptor	receptor	NN
cord-310847-63gh2tg4	555	23	and	and	CC
cord-310847-63gh2tg4	555	24	other	other	JJ
cord-310847-63gh2tg4	555	25	nuclear	nuclear	JJ
cord-310847-63gh2tg4	555	26	hormone	hormone	NN
cord-310847-63gh2tg4	555	27	receptors	receptor	NNS
cord-310847-63gh2tg4	555	28	,	,	,
cord-310847-63gh2tg4	555	29	a	a	DT
cord-310847-63gh2tg4	555	30	zinc	zinc	NN
cord-310847-63gh2tg4	555	31	finger	finger	NN
cord-310847-63gh2tg4	555	32	,	,	,
cord-310847-63gh2tg4	555	33	a	a	DT
cord-310847-63gh2tg4	555	34	glutamic	glutamic	NN
cord-310847-63gh2tg4	555	35	acid	acid	NN
cord-310847-63gh2tg4	555	36	-	-	HYPH
cord-310847-63gh2tg4	555	37	rich	rich	JJ
cord-310847-63gh2tg4	555	38	domain	domain	NN
cord-310847-63gh2tg4	555	39	and	and	CC
cord-310847-63gh2tg4	555	40	two	two	CD
cord-310847-63gh2tg4	555	41	proline	proline	JJ
cord-310847-63gh2tg4	555	42	-	-	HYPH
cord-310847-63gh2tg4	555	43	rich	rich	JJ
cord-310847-63gh2tg4	555	44	domains	domain	NNS
cord-310847-63gh2tg4	555	45	.	.	.
cord-310847-63gh2tg4	556	1	191	191	CD
cord-310847-63gh2tg4	557	1	There	there	EX
cord-310847-63gh2tg4	557	2	are	be	VBP
cord-310847-63gh2tg4	557	3	several	several	JJ
cord-310847-63gh2tg4	557	4	consensus	consensus	NN
cord-310847-63gh2tg4	557	5	PXXP	PXXP	NNP
cord-310847-63gh2tg4	557	6	motifs	motif	NNS
cord-310847-63gh2tg4	557	7	within	within	IN
cord-310847-63gh2tg4	557	8	the	the	DT
cord-310847-63gh2tg4	557	9	proline	proline	JJ
cord-310847-63gh2tg4	557	10	-	-	HYPH
cord-310847-63gh2tg4	557	11	rich	rich	JJ
cord-310847-63gh2tg4	557	12	regions	region	NNS
cord-310847-63gh2tg4	557	13	,	,	,
cord-310847-63gh2tg4	557	14	via	via	IN
cord-310847-63gh2tg4	557	15	which	which	WDT
cord-310847-63gh2tg4	557	16	PELP1	PELP1	NNP
cord-310847-63gh2tg4	557	17	couples	couple	VBZ
cord-310847-63gh2tg4	557	18	the	the	DT
cord-310847-63gh2tg4	557	19	estrogen	estrogen	NN
cord-310847-63gh2tg4	557	20	receptor	receptor	NN
cord-310847-63gh2tg4	557	21	(	(	-LRB-
cord-310847-63gh2tg4	557	22	ER	ER	NNP
cord-310847-63gh2tg4	557	23	)	)	-RRB-
cord-310847-63gh2tg4	557	24	with	with	IN
cord-310847-63gh2tg4	557	25	SH3	SH3	NNP
cord-310847-63gh2tg4	557	26	domain	domain	NN
cord-310847-63gh2tg4	557	27	-	-	HYPH
cord-310847-63gh2tg4	557	28	containing	contain	VBG
cord-310847-63gh2tg4	557	29	kinase	kinase	NN
cord-310847-63gh2tg4	557	30	signaling	signal	VBG
cord-310847-63gh2tg4	557	31	proteins	protein	NNS
cord-310847-63gh2tg4	557	32	,	,	,
cord-310847-63gh2tg4	557	33	such	such	JJ
cord-310847-63gh2tg4	557	34	as	as	IN
cord-310847-63gh2tg4	557	35	Src	Src	NNP
cord-310847-63gh2tg4	557	36	and	and	CC
cord-310847-63gh2tg4	557	37	PI3	PI3	NNP
cord-310847-63gh2tg4	557	38	K	K	NNP
cord-310847-63gh2tg4	557	39	P85	P85	NNP
cord-310847-63gh2tg4	557	40	regulatory	regulatory	JJ
cord-310847-63gh2tg4	557	41	subunit	subunit	NN
cord-310847-63gh2tg4	557	42	.	.	.
cord-310847-63gh2tg4	558	1	191	191	CD
cord-310847-63gh2tg4	559	1	There	there	EX
cord-310847-63gh2tg4	559	2	are	be	VBP
cord-310847-63gh2tg4	559	3	148	148	CD
cord-310847-63gh2tg4	559	4	glutamic	glutamic	NN
cord-310847-63gh2tg4	559	5	acids	acid	NNS
cord-310847-63gh2tg4	559	6	in	in	IN
cord-310847-63gh2tg4	559	7	PELP1	PELP1	NNP
cord-310847-63gh2tg4	559	8	(	(	-LRB-
cord-310847-63gh2tg4	559	9	which	which	WDT
cord-310847-63gh2tg4	559	10	is	be	VBZ
cord-310847-63gh2tg4	559	11	1,130	1,130	CD
cord-310847-63gh2tg4	559	12	residues	residue	NNS
cord-310847-63gh2tg4	559	13	long	long	RB
cord-310847-63gh2tg4	559	14	)	)	-RRB-
cord-310847-63gh2tg4	559	15	,	,	,
cord-310847-63gh2tg4	559	16	and	and	CC
cord-310847-63gh2tg4	559	17	the	the	DT
cord-310847-63gh2tg4	559	18	majority	majority	NN
cord-310847-63gh2tg4	559	19	of	of	IN
cord-310847-63gh2tg4	559	20	them	-PRON-	PRP
cord-310847-63gh2tg4	559	21	(	(	-LRB-
cord-310847-63gh2tg4	559	22	99	99	CD
cord-310847-63gh2tg4	559	23	)	)	-RRB-
cord-310847-63gh2tg4	559	24	are	be	VBP
cord-310847-63gh2tg4	559	25	concentrated	concentrate	VBN
cord-310847-63gh2tg4	559	26	within	within	IN
cord-310847-63gh2tg4	559	27	the	the	DT
cord-310847-63gh2tg4	559	28	glutamic	glutamic	NN
cord-310847-63gh2tg4	559	29	acid	acid	NN
cord-310847-63gh2tg4	559	30	-	-	HYPH
cord-310847-63gh2tg4	559	31	rich	rich	JJ
cord-310847-63gh2tg4	559	32	domain	domain	NN
cord-310847-63gh2tg4	559	33	(	(	-LRB-
cord-310847-63gh2tg4	559	34	residues	residue	NNS
cord-310847-63gh2tg4	559	35	888	888	CD
cord-310847-63gh2tg4	559	36	-	-	HYPH
cord-310847-63gh2tg4	559	37	1101	1101	CD
cord-310847-63gh2tg4	559	38	)	)	-RRB-
cord-310847-63gh2tg4	559	39	.	.	.
cord-310847-63gh2tg4	560	1	eIF5	eif5	UH
cord-310847-63gh2tg4	560	2	.	.	.
cord-310847-63gh2tg4	561	1	Eukaryotic	eukaryotic	JJ
cord-310847-63gh2tg4	561	2	translation	translation	NN
cord-310847-63gh2tg4	561	3	initiation	initiation	NN
cord-310847-63gh2tg4	561	4	factor	factor	NN
cord-310847-63gh2tg4	561	5	5	5	CD
cord-310847-63gh2tg4	562	1	(	(	-LRB-
cord-310847-63gh2tg4	562	2	eIF5	eIF5	NNP
cord-310847-63gh2tg4	562	3	)	)	-RRB-
cord-310847-63gh2tg4	562	4	is	be	VBZ
cord-310847-63gh2tg4	562	5	a	a	DT
cord-310847-63gh2tg4	562	6	monomeric	monomeric	JJ
cord-310847-63gh2tg4	562	7	protein	protein	NN
cord-310847-63gh2tg4	562	8	of	of	IN
cord-310847-63gh2tg4	562	9	about	about	RB
cord-310847-63gh2tg4	562	10	49	49	CD
cord-310847-63gh2tg4	562	11	kDa	kDa	NNS
cord-310847-63gh2tg4	562	12	that	that	IN
cord-310847-63gh2tg4	562	13	functions	function	VBZ
cord-310847-63gh2tg4	562	14	as	as	IN
cord-310847-63gh2tg4	562	15	a	a	DT
cord-310847-63gh2tg4	562	16	GTPaseactivating	gtpaseactivate	VBG
cord-310847-63gh2tg4	562	17	protein	protein	NN
cord-310847-63gh2tg4	562	18	(	(	-LRB-
cord-310847-63gh2tg4	562	19	GAP	gap	NN
cord-310847-63gh2tg4	562	20	)	)	-RRB-
cord-310847-63gh2tg4	562	21	in	in	IN
cord-310847-63gh2tg4	562	22	translation	translation	NN
cord-310847-63gh2tg4	562	23	initiation	initiation	NN
cord-310847-63gh2tg4	562	24	.	.	.
cord-310847-63gh2tg4	563	1	eIF5	eif5	IN
cord-310847-63gh2tg4	564	1	is	be	VBZ
cord-310847-63gh2tg4	564	2	involved	involve	VBN
cord-310847-63gh2tg4	564	3	in	in	IN
cord-310847-63gh2tg4	564	4	initiation	initiation	NN
cord-310847-63gh2tg4	564	5	of	of	IN
cord-310847-63gh2tg4	564	6	protein	protein	NN
cord-310847-63gh2tg4	564	7	synthesis	synthesis	NN
cord-310847-63gh2tg4	564	8	in	in	IN
cord-310847-63gh2tg4	564	9	eukaryotic	eukaryotic	JJ
cord-310847-63gh2tg4	564	10	cells	cell	NNS
cord-310847-63gh2tg4	564	11	,	,	,
cord-310847-63gh2tg4	564	12	where	where	WRB
cord-310847-63gh2tg4	564	13	,	,	,
cord-310847-63gh2tg4	564	14	after	after	IN
cord-310847-63gh2tg4	564	15	binding	bind	VBG
cord-310847-63gh2tg4	564	16	to	to	IN
cord-310847-63gh2tg4	564	17	the	the	DT
cord-310847-63gh2tg4	564	18	40S	40s	CD
cord-310847-63gh2tg4	564	19	initiation	initiation	NN
cord-310847-63gh2tg4	564	20	complex	complex	NN
cord-310847-63gh2tg4	564	21	(	(	-LRB-
cord-310847-63gh2tg4	564	22	40S	40s	CD
cord-310847-63gh2tg4	564	23	-	-	HYPH
cord-310847-63gh2tg4	564	24	eIF3-mRNA	eif3-mrna	NN
cord-310847-63gh2tg4	564	25	-	-	HYPH
cord-310847-63gh2tg4	564	26	Met	Met	NNP
cord-310847-63gh2tg4	564	27	-	-	HYPH
cord-310847-63gh2tg4	564	28	tRNA	tRNA	NNP
cord-310847-63gh2tg4	564	29	f	f	NNP
cord-310847-63gh2tg4	564	30	-eIF2-GTP	-eIF2-GTP	''
cord-310847-63gh2tg4	564	31	)	)	-RRB-
cord-310847-63gh2tg4	564	32	at	at	IN
cord-310847-63gh2tg4	564	33	the	the	DT
cord-310847-63gh2tg4	564	34	AUG	AUG	NNP
cord-310847-63gh2tg4	564	35	codon	codon	NN
cord-310847-63gh2tg4	564	36	of	of	IN
cord-310847-63gh2tg4	564	37	an	an	DT
cord-310847-63gh2tg4	564	38	mRNA	mrna	NN
cord-310847-63gh2tg4	564	39	,	,	,
cord-310847-63gh2tg4	564	40	it	-PRON-	PRP
cord-310847-63gh2tg4	564	41	promotes	promote	VBZ
cord-310847-63gh2tg4	564	42	GTP	GTP	NNP
cord-310847-63gh2tg4	564	43	hydrolysis	hydrolysis	NN
cord-310847-63gh2tg4	564	44	.	.	.
cord-310847-63gh2tg4	565	1	This	this	DT
cord-310847-63gh2tg4	565	2	initiates	initiate	VBZ
cord-310847-63gh2tg4	565	3	a	a	DT
cord-310847-63gh2tg4	565	4	cascade	cascade	NN
cord-310847-63gh2tg4	565	5	of	of	IN
cord-310847-63gh2tg4	565	6	events	event	NNS
cord-310847-63gh2tg4	565	7	that	that	WDT
cord-310847-63gh2tg4	565	8	starts	start	VBZ
cord-310847-63gh2tg4	565	9	from	from	IN
cord-310847-63gh2tg4	565	10	the	the	DT
cord-310847-63gh2tg4	565	11	release	release	NN
cord-310847-63gh2tg4	565	12	of	of	IN
cord-310847-63gh2tg4	565	13	bound	bind	VBN
cord-310847-63gh2tg4	565	14	initiation	initiation	NN
cord-310847-63gh2tg4	565	15	factors	factor	NNS
cord-310847-63gh2tg4	565	16	from	from	IN
cord-310847-63gh2tg4	565	17	the	the	DT
cord-310847-63gh2tg4	565	18	40S	40s	CD
cord-310847-63gh2tg4	565	19	subunit	subunit	NN
cord-310847-63gh2tg4	565	20	and	and	CC
cord-310847-63gh2tg4	565	21	ends	end	VBZ
cord-310847-63gh2tg4	565	22	with	with	IN
cord-310847-63gh2tg4	565	23	the	the	DT
cord-310847-63gh2tg4	565	24	joining	joining	NN
cord-310847-63gh2tg4	565	25	of	of	IN
cord-310847-63gh2tg4	565	26	the	the	DT
cord-310847-63gh2tg4	565	27	60S	60s	CD
cord-310847-63gh2tg4	565	28	ribosomal	ribosomal	JJ
cord-310847-63gh2tg4	565	29	subunit	subunit	NN
cord-310847-63gh2tg4	565	30	to	to	IN
cord-310847-63gh2tg4	565	31	the	the	DT
cord-310847-63gh2tg4	565	32	40S	40s	CD
cord-310847-63gh2tg4	565	33	complex	complex	JJ
cord-310847-63gh2tg4	565	34	to	to	TO
cord-310847-63gh2tg4	565	35	form	form	VB
cord-310847-63gh2tg4	565	36	the	the	DT
cord-310847-63gh2tg4	565	37	functional	functional	JJ
cord-310847-63gh2tg4	565	38	80S	80s	CD
cord-310847-63gh2tg4	565	39	initiation	initiation	NN
cord-310847-63gh2tg4	565	40	complex	complex	NN
cord-310847-63gh2tg4	565	41	(	(	-LRB-
cord-310847-63gh2tg4	565	42	80S	80S	NNP
cord-310847-63gh2tg4	565	43	-	-	HYPH
cord-310847-63gh2tg4	565	44	mRNA	mrna	NN
cord-310847-63gh2tg4	565	45	-	-	HYPH
cord-310847-63gh2tg4	565	46	Met	Met	NNP
cord-310847-63gh2tg4	565	47	-	-	HYPH
cord-310847-63gh2tg4	565	48	tRNA	tRNA	NNP
cord-310847-63gh2tg4	565	49	f	f	NNP
cord-310847-63gh2tg4	565	50	)	)	-RRB-
cord-310847-63gh2tg4	565	51	.	.	.
cord-310847-63gh2tg4	566	1	193	193	CD
cord-310847-63gh2tg4	567	1	Although	although	IN
cord-310847-63gh2tg4	567	2	eIF5	eIF5	NNP
cord-310847-63gh2tg4	567	3	binds	bind	VBZ
cord-310847-63gh2tg4	567	4	GTP	GTP	NNP
cord-310847-63gh2tg4	567	5	and	and	CC
cord-310847-63gh2tg4	567	6	is	be	VBZ
cord-310847-63gh2tg4	567	7	able	able	JJ
cord-310847-63gh2tg4	567	8	to	to	TO
cord-310847-63gh2tg4	567	9	promote	promote	VB
cord-310847-63gh2tg4	567	10	GTP	GTP	NNP
cord-310847-63gh2tg4	567	11	hydrolysis	hydrolysis	NN
cord-310847-63gh2tg4	567	12	reaction	reaction	NN
cord-310847-63gh2tg4	567	13	,	,	,
cord-310847-63gh2tg4	567	14	it	-PRON-	PRP
cord-310847-63gh2tg4	567	15	does	do	VBZ
cord-310847-63gh2tg4	567	16	not	not	RB
cord-310847-63gh2tg4	567	17	hydrolyze	hydrolyze	VB
cord-310847-63gh2tg4	567	18	GTP	GTP	NNP
cord-310847-63gh2tg4	567	19	by	by	IN
cord-310847-63gh2tg4	567	20	itself	-PRON-	PRP
cord-310847-63gh2tg4	567	21	acting	act	VBG
cord-310847-63gh2tg4	567	22	as	as	IN
cord-310847-63gh2tg4	567	23	a	a	DT
cord-310847-63gh2tg4	567	24	typical	typical	JJ
cord-310847-63gh2tg4	567	25	GTPase	GTPase	NNP
cord-310847-63gh2tg4	567	26	-	-	HYPH
cord-310847-63gh2tg4	567	27	activating	activate	VBG
cord-310847-63gh2tg4	567	28	protein	protein	NN
cord-310847-63gh2tg4	567	29	(	(	-LRB-
cord-310847-63gh2tg4	567	30	GAP	gap	NN
cord-310847-63gh2tg4	567	31	)	)	-RRB-
cord-310847-63gh2tg4	567	32	.	.	.
cord-310847-63gh2tg4	568	1	In	in	IN
cord-310847-63gh2tg4	568	2	fact	fact	NN
cord-310847-63gh2tg4	568	3	,	,	,
cord-310847-63gh2tg4	568	4	eIF5	eif5	IN
cord-310847-63gh2tg4	568	5	forms	form	VBZ
cord-310847-63gh2tg4	568	6	a	a	DT
cord-310847-63gh2tg4	568	7	complex	complex	NN
cord-310847-63gh2tg4	568	8	with	with	IN
cord-310847-63gh2tg4	568	9	eIF2	eIF2	NNP
cord-310847-63gh2tg4	568	10	via	via	IN
cord-310847-63gh2tg4	568	11	its	-PRON-	PRP$
cord-310847-63gh2tg4	568	12	glutamic	glutamic	NN
cord-310847-63gh2tg4	568	13	acidrich	acidrich	NNP
cord-310847-63gh2tg4	568	14	C	C	NNP
cord-310847-63gh2tg4	568	15	-	-	HYPH
cord-310847-63gh2tg4	568	16	terminal	terminal	NN
cord-310847-63gh2tg4	568	17	region	region	NN
cord-310847-63gh2tg4	568	18	that	that	WDT
cord-310847-63gh2tg4	568	19	binds	bind	VBZ
cord-310847-63gh2tg4	568	20	to	to	IN
cord-310847-63gh2tg4	568	21	the	the	DT
cord-310847-63gh2tg4	568	22	lysine	lysine	NN
cord-310847-63gh2tg4	568	23	-	-	HYPH
cord-310847-63gh2tg4	568	24	rich	rich	JJ
cord-310847-63gh2tg4	568	25	N	n	CD
cord-310847-63gh2tg4	568	26	-	-	HYPH
cord-310847-63gh2tg4	568	27	terminal	terminal	NN
cord-310847-63gh2tg4	568	28	region	region	NN
cord-310847-63gh2tg4	568	29	of	of	IN
cord-310847-63gh2tg4	568	30	the	the	DT
cord-310847-63gh2tg4	568	31	β	β	NN
cord-310847-63gh2tg4	568	32	-	-	HYPH
cord-310847-63gh2tg4	568	33	subunit	subunit	NN
cord-310847-63gh2tg4	568	34	of	of	IN
cord-310847-63gh2tg4	568	35	eIF2	eIF2	NNP
cord-310847-63gh2tg4	568	36	thus	thus	RB
cord-310847-63gh2tg4	568	37	activating	activate	VBG
cord-310847-63gh2tg4	568	38	the	the	DT
cord-310847-63gh2tg4	568	39	GTPase	GTPase	NNP
cord-310847-63gh2tg4	568	40	activity	activity	NN
cord-310847-63gh2tg4	568	41	of	of	IN
cord-310847-63gh2tg4	568	42	eIF2	eIF2	NNP
cord-310847-63gh2tg4	568	43	.	.	.
cord-310847-63gh2tg4	569	1	193	193	CD
cord-310847-63gh2tg4	570	1	In	in	IN
cord-310847-63gh2tg4	570	2	human	human	NN
cord-310847-63gh2tg4	570	3	eIF5	eif5	IN
cord-310847-63gh2tg4	570	4	,	,	,
cord-310847-63gh2tg4	570	5	the	the	DT
cord-310847-63gh2tg4	570	6	3D	3d	JJ
cord-310847-63gh2tg4	570	7	structure	structure	NN
cord-310847-63gh2tg4	570	8	is	be	VBZ
cord-310847-63gh2tg4	570	9	known	know	VBN
cord-310847-63gh2tg4	570	10	for	for	IN
cord-310847-63gh2tg4	570	11	the	the	DT
cord-310847-63gh2tg4	570	12	N	n	CD
cord-310847-63gh2tg4	570	13	-	-	HYPH
cord-310847-63gh2tg4	570	14	terminal	terminal	NN
cord-310847-63gh2tg4	570	15	nucleotide	nucleotide	JJ
cord-310847-63gh2tg4	570	16	binding	bind	VBG
cord-310847-63gh2tg4	570	17	domain	domain	NN
cord-310847-63gh2tg4	570	18	(	(	-LRB-
cord-310847-63gh2tg4	570	19	residues	residue	NNS
cord-310847-63gh2tg4	570	20	1	1	CD
cord-310847-63gh2tg4	570	21	-	-	SYM
cord-310847-63gh2tg4	570	22	150	150	CD
cord-310847-63gh2tg4	570	23	,	,	,
cord-310847-63gh2tg4	570	24	PDB	PDB	NNP
cord-310847-63gh2tg4	570	25	ID	ID	NNP
cord-310847-63gh2tg4	570	26	:	:	:
cord-310847-63gh2tg4	570	27	2E9H	2e9h	CD
cord-310847-63gh2tg4	570	28	)	)	-RRB-
cord-310847-63gh2tg4	570	29	and	and	CC
cord-310847-63gh2tg4	570	30	for	for	IN
cord-310847-63gh2tg4	570	31	the	the	DT
cord-310847-63gh2tg4	570	32	W2	W2	NNP
cord-310847-63gh2tg4	570	33	domain	domain	NN
cord-310847-63gh2tg4	570	34	(	(	-LRB-
cord-310847-63gh2tg4	570	35	residues	residue	NNS
cord-310847-63gh2tg4	570	36	232	232	CD
cord-310847-63gh2tg4	570	37	-	-	SYM
cord-310847-63gh2tg4	570	38	431	431	CD
cord-310847-63gh2tg4	570	39	,	,	,
cord-310847-63gh2tg4	570	40	PDB	PDB	NNP
cord-310847-63gh2tg4	570	41	ID	ID	NNP
cord-310847-63gh2tg4	570	42	:	:	:
cord-310847-63gh2tg4	570	43	2IU1	2iu1	CD
cord-310847-63gh2tg4	570	44	)	)	-RRB-
cord-310847-63gh2tg4	570	45	.	.	.
cord-310847-63gh2tg4	571	1	The	the	DT
cord-310847-63gh2tg4	571	2	linker	linker	NN
cord-310847-63gh2tg4	571	3	region	region	NN
cord-310847-63gh2tg4	571	4	connecting	connect	VBG
cord-310847-63gh2tg4	571	5	these	these	DT
cord-310847-63gh2tg4	571	6	two	two	CD
cord-310847-63gh2tg4	571	7	domains	domain	NNS
cord-310847-63gh2tg4	571	8	is	be	VBZ
cord-310847-63gh2tg4	571	9	highly	highly	RB
cord-310847-63gh2tg4	571	10	disordered	disordered	JJ
cord-310847-63gh2tg4	571	11	and	and	CC
cord-310847-63gh2tg4	571	12	contains	contain	VBZ
cord-310847-63gh2tg4	571	13	one	one	CD
cord-310847-63gh2tg4	571	14	of	of	IN
cord-310847-63gh2tg4	571	15	the	the	DT
cord-310847-63gh2tg4	571	16	functionally	functionally	RB
cord-310847-63gh2tg4	571	17	important	important	JJ
cord-310847-63gh2tg4	571	18	glutamic	glutamic	NN
cord-310847-63gh2tg4	571	19	acid	acid	NN
cord-310847-63gh2tg4	571	20	-	-	HYPH
cord-310847-63gh2tg4	571	21	rich	rich	JJ
cord-310847-63gh2tg4	571	22	regions	region	NNS
cord-310847-63gh2tg4	571	23	(	(	-LRB-
cord-310847-63gh2tg4	571	24	residues	residue	NNS
cord-310847-63gh2tg4	571	25	[	[	-LRB-
cord-310847-63gh2tg4	571	26	196	196	CD
cord-310847-63gh2tg4	571	27	]	]	-RRB-
cord-310847-63gh2tg4	571	28	[	[	-LRB-
cord-310847-63gh2tg4	571	29	197	197	CD
cord-310847-63gh2tg4	571	30	]	]	-RRB-
cord-310847-63gh2tg4	571	31	[	[	-LRB-
cord-310847-63gh2tg4	571	32	198	198	CD
cord-310847-63gh2tg4	571	33	]	]	-RRB-
cord-310847-63gh2tg4	571	34	[	[	-LRB-
cord-310847-63gh2tg4	571	35	199	199	CD
cord-310847-63gh2tg4	571	36	]	]	-RRB-
cord-310847-63gh2tg4	571	37	[	[	-LRB-
cord-310847-63gh2tg4	571	38	200	200	CD
cord-310847-63gh2tg4	571	39	]	]	-RRB-
cord-310847-63gh2tg4	571	40	[	[	-LRB-
cord-310847-63gh2tg4	571	41	201	201	CD
cord-310847-63gh2tg4	571	42	]	]	-RRB-
cord-310847-63gh2tg4	571	43	[	[	-LRB-
cord-310847-63gh2tg4	571	44	202	202	CD
cord-310847-63gh2tg4	571	45	]	]	-RRB-
cord-310847-63gh2tg4	571	46	.	.	.
cord-310847-63gh2tg4	572	1	Overall	overall	RB
cord-310847-63gh2tg4	572	2	,	,	,
cord-310847-63gh2tg4	572	3	there	there	EX
cord-310847-63gh2tg4	572	4	are	be	VBP
cord-310847-63gh2tg4	572	5	11.4	11.4	CD
cord-310847-63gh2tg4	572	6	%	%	NN
cord-310847-63gh2tg4	572	7	glutamic	glutamic	NN
cord-310847-63gh2tg4	572	8	acid	acid	NN
cord-310847-63gh2tg4	572	9	residues	residue	NNS
cord-310847-63gh2tg4	572	10	in	in	IN
cord-310847-63gh2tg4	572	11	the	the	DT
cord-310847-63gh2tg4	572	12	431	431	CD
cord-310847-63gh2tg4	572	13	residues	residue	NNS
cord-310847-63gh2tg4	572	14	-	-	HYPH
cord-310847-63gh2tg4	572	15	long	long	JJ
cord-310847-63gh2tg4	572	16	amino	amino	NN
cord-310847-63gh2tg4	572	17	acid	acid	NN
cord-310847-63gh2tg4	572	18	sequence	sequence	NN
cord-310847-63gh2tg4	572	19	of	of	IN
cord-310847-63gh2tg4	572	20	human	human	NN
cord-310847-63gh2tg4	572	21	eIF5	eif5	IN
cord-310847-63gh2tg4	572	22	.	.	.
cord-310847-63gh2tg4	573	1	Histone	Histone	NNP
cord-310847-63gh2tg4	573	2	-	-	HYPH
cord-310847-63gh2tg4	573	3	interacting	interact	VBG
cord-310847-63gh2tg4	573	4	proteins	protein	NNS
cord-310847-63gh2tg4	573	5	.	.	.
cord-310847-63gh2tg4	574	1	Since	since	IN
cord-310847-63gh2tg4	574	2	histones	histone	NNS
cord-310847-63gh2tg4	574	3	are	be	VBP
cord-310847-63gh2tg4	574	4	polycations	polycation	NNS
cord-310847-63gh2tg4	574	5	,	,	,
cord-310847-63gh2tg4	574	6	they	-PRON-	PRP
cord-310847-63gh2tg4	574	7	are	be	VBP
cord-310847-63gh2tg4	574	8	known	know	VBN
cord-310847-63gh2tg4	574	9	to	to	TO
cord-310847-63gh2tg4	574	10	be	be	VB
cord-310847-63gh2tg4	574	11	involved	involve	VBN
cord-310847-63gh2tg4	574	12	in	in	IN
cord-310847-63gh2tg4	574	13	interactions	interaction	NNS
cord-310847-63gh2tg4	574	14	with	with	IN
cord-310847-63gh2tg4	574	15	several	several	JJ
cord-310847-63gh2tg4	574	16	polyanionic	polyanionic	JJ
cord-310847-63gh2tg4	574	17	proteins	protein	NNS
cord-310847-63gh2tg4	574	18	,	,	,
cord-310847-63gh2tg4	574	19	particularly	particularly	RB
cord-310847-63gh2tg4	574	20	with	with	IN
cord-310847-63gh2tg4	574	21	proteins	protein	NNS
cord-310847-63gh2tg4	574	22	containing	contain	VBG
cord-310847-63gh2tg4	574	23	glutamic	glutamic	NN
cord-310847-63gh2tg4	574	24	which	which	WDT
cord-310847-63gh2tg4	574	25	are	be	VBP
cord-310847-63gh2tg4	574	26	located	locate	VBN
cord-310847-63gh2tg4	574	27	outside	outside	IN
cord-310847-63gh2tg4	574	28	the	the	DT
cord-310847-63gh2tg4	574	29	catalytic	catalytic	JJ
cord-310847-63gh2tg4	574	30	domain	domain	NN
cord-310847-63gh2tg4	574	31	,	,	,
cord-310847-63gh2tg4	574	32	with	with	IN
cord-310847-63gh2tg4	574	33	respectively	respectively	RB
cord-310847-63gh2tg4	574	34	44	44	CD
cord-310847-63gh2tg4	574	35	,	,	,
cord-310847-63gh2tg4	574	36	32	32	CD
cord-310847-63gh2tg4	574	37	,	,	,
cord-310847-63gh2tg4	574	38	53	53	CD
cord-310847-63gh2tg4	574	39	,	,	,
cord-310847-63gh2tg4	574	40	59	59	CD
cord-310847-63gh2tg4	574	41	and	and	CC
cord-310847-63gh2tg4	574	42	39	39	CD
cord-310847-63gh2tg4	574	43	glutamates	glutamate	NNS
cord-310847-63gh2tg4	574	44	,	,	,
cord-310847-63gh2tg4	574	45	aspartates	aspartates	NNPS
cord-310847-63gh2tg4	574	46	,	,	,
cord-310847-63gh2tg4	574	47	prolines	prolines	NNP
cord-310847-63gh2tg4	574	48	,	,	,
cord-310847-63gh2tg4	574	49	serines	serines	NNPS
cord-310847-63gh2tg4	574	50	and	and	CC
cord-310847-63gh2tg4	574	51	threonines	threonine	NNS
cord-310847-63gh2tg4	574	52	being	be	VBG
cord-310847-63gh2tg4	574	53	found	find	VBN
cord-310847-63gh2tg4	574	54	in	in	IN
cord-310847-63gh2tg4	574	55	the	the	DT
cord-310847-63gh2tg4	574	56	non	non	JJ
cord-310847-63gh2tg4	574	57	-	-	JJ
cord-310847-63gh2tg4	574	58	catalytic	catalytic	JJ
cord-310847-63gh2tg4	574	59	region	region	NN
cord-310847-63gh2tg4	574	60	(	(	-LRB-
cord-310847-63gh2tg4	574	61	residues	residue	NNS
cord-310847-63gh2tg4	574	62	294	294	CD
cord-310847-63gh2tg4	574	63	-	-	HYPH
cord-310847-63gh2tg4	574	64	780	780	CD
cord-310847-63gh2tg4	574	65	)	)	-RRB-
cord-310847-63gh2tg4	574	66	.	.	.
cord-310847-63gh2tg4	575	1	Finally	finally	RB
cord-310847-63gh2tg4	575	2	,	,	,
cord-310847-63gh2tg4	575	3	among	among	IN
cord-310847-63gh2tg4	575	4	the	the	DT
cord-310847-63gh2tg4	575	5	460	460	CD
cord-310847-63gh2tg4	575	6	residues	residue	NNS
cord-310847-63gh2tg4	575	7	of	of	IN
cord-310847-63gh2tg4	575	8	the	the	DT
cord-310847-63gh2tg4	575	9	human	human	JJ
cord-310847-63gh2tg4	575	10	PTP	PTP	NNP
cord-310847-63gh2tg4	575	11	-	-	HYPH
cord-310847-63gh2tg4	575	12	HSCF	HSCF	NNP
cord-310847-63gh2tg4	576	1	(	(	-LRB-
cord-310847-63gh2tg4	576	2	BDP1	BDP1	NNP
cord-310847-63gh2tg4	576	3	/	/	SYM
cord-310847-63gh2tg4	576	4	PTP20	PTP20	NNP
cord-310847-63gh2tg4	576	5	/	/	SYM
cord-310847-63gh2tg4	576	6	PTP	PTP	NNP
cord-310847-63gh2tg4	576	7	-	-	HYPH
cord-310847-63gh2tg4	576	8	K1	K1	NNP
cord-310847-63gh2tg4	576	9	/	/	SYM
cord-310847-63gh2tg4	576	10	FLP1	FLP1	NNP
cord-310847-63gh2tg4	576	11	/	/	SYM
cord-310847-63gh2tg4	576	12	PTPN18	PTPN18	NNP
cord-310847-63gh2tg4	576	13	)	)	-RRB-
cord-310847-63gh2tg4	576	14	,	,	,
cord-310847-63gh2tg4	576	15	there	there	EX
cord-310847-63gh2tg4	576	16	are	be	VBP
cord-310847-63gh2tg4	576	17	27	27	CD
cord-310847-63gh2tg4	576	18	glutamic	glutamic	JJ
cord-310847-63gh2tg4	576	19	acids	acid	NNS
cord-310847-63gh2tg4	576	20	,	,	,
cord-310847-63gh2tg4	576	21	21	21	CD
cord-310847-63gh2tg4	576	22	aspartic	aspartic	JJ
cord-310847-63gh2tg4	576	23	acids	acid	NNS
cord-310847-63gh2tg4	576	24	,	,	,
cord-310847-63gh2tg4	576	25	32	32	CD
cord-310847-63gh2tg4	576	26	prolines	proline	NNS
cord-310847-63gh2tg4	576	27	,	,	,
cord-310847-63gh2tg4	576	28	29	29	CD
cord-310847-63gh2tg4	576	29	serines	serine	NNS
cord-310847-63gh2tg4	576	30	and	and	CC
cord-310847-63gh2tg4	576	31	25	25	CD
cord-310847-63gh2tg4	576	32	threonines	threonine	NNS
cord-310847-63gh2tg4	576	33	.	.	.
cord-310847-63gh2tg4	577	1	Importantly	importantly	RB
cord-310847-63gh2tg4	577	2	,	,	,
cord-310847-63gh2tg4	577	3	glutamate	glutamate	NN
cord-310847-63gh2tg4	577	4	-	-	HYPH
cord-310847-63gh2tg4	577	5	rich	rich	JJ
cord-310847-63gh2tg4	577	6	,	,	,
cord-310847-63gh2tg4	577	7	non	non	JJ
cord-310847-63gh2tg4	577	8	-	-	JJ
cord-310847-63gh2tg4	577	9	catalytic	catalytic	JJ
cord-310847-63gh2tg4	577	10	regions	region	NNS
cord-310847-63gh2tg4	577	11	of	of	IN
cord-310847-63gh2tg4	577	12	all	all	PDT
cord-310847-63gh2tg4	577	13	these	these	DT
cord-310847-63gh2tg4	577	14	PTPs	ptp	NNS
cord-310847-63gh2tg4	577	15	are	be	VBP
cord-310847-63gh2tg4	577	16	known	know	VBN
cord-310847-63gh2tg4	577	17	to	to	TO
cord-310847-63gh2tg4	577	18	be	be	VB
cord-310847-63gh2tg4	577	19	involved	involve	VBN
cord-310847-63gh2tg4	577	20	in	in	IN
cord-310847-63gh2tg4	577	21	interactions	interaction	NNS
cord-310847-63gh2tg4	577	22	with	with	IN
cord-310847-63gh2tg4	577	23	multiple	multiple	JJ
cord-310847-63gh2tg4	577	24	binding	bind	VBG
cord-310847-63gh2tg4	577	25	partners	partner	NNS
cord-310847-63gh2tg4	577	26	.	.	.
cord-310847-63gh2tg4	578	1	For	for	IN
cord-310847-63gh2tg4	578	2	example	example	NN
cord-310847-63gh2tg4	578	3	,	,	,
cord-310847-63gh2tg4	578	4	PTP	PTP	NNP
cord-310847-63gh2tg4	578	5	-	-	HYPH
cord-310847-63gh2tg4	578	6	LYP	LYP	NNP
cord-310847-63gh2tg4	578	7	is	be	VBZ
cord-310847-63gh2tg4	578	8	involved	involve	VBN
cord-310847-63gh2tg4	578	9	in	in	IN
cord-310847-63gh2tg4	578	10	interaction	interaction	NN
cord-310847-63gh2tg4	578	11	with	with	IN
cord-310847-63gh2tg4	578	12	Grb2	Grb2	NNP
cord-310847-63gh2tg4	578	13	,	,	,
cord-310847-63gh2tg4	578	14	c	c	NN
cord-310847-63gh2tg4	578	15	-	-	:
cord-310847-63gh2tg4	578	16	Cbl	Cbl	NNP
cord-310847-63gh2tg4	578	17	,	,	,
cord-310847-63gh2tg4	578	18	and	and	CC
cord-310847-63gh2tg4	578	19	the	the	DT
cord-310847-63gh2tg4	578	20	C	C	NNP
cord-310847-63gh2tg4	578	21	-	-	HYPH
cord-310847-63gh2tg4	578	22	terminal	terminal	NN
cord-310847-63gh2tg4	578	23	Src	Src	NNP
cord-310847-63gh2tg4	578	24	kinase	kinase	NN
cord-310847-63gh2tg4	578	25	(	(	-LRB-
cord-310847-63gh2tg4	578	26	Csk	Csk	NNP
cord-310847-63gh2tg4	578	27	)	)	-RRB-
cord-310847-63gh2tg4	578	28	,	,	,
cord-310847-63gh2tg4	578	29	which	which	WDT
cord-310847-63gh2tg4	578	30	is	be	VBZ
cord-310847-63gh2tg4	578	31	the	the	DT
cord-310847-63gh2tg4	578	32	inhibitory	inhibitory	JJ
cord-310847-63gh2tg4	578	33	protein	protein	NN
cord-310847-63gh2tg4	578	34	tyrosine	tyrosine	NN
cord-310847-63gh2tg4	578	35	kinase	kinase	NN
cord-310847-63gh2tg4	578	36	(	(	-LRB-
cord-310847-63gh2tg4	578	37	PTK	PTK	NNP
cord-310847-63gh2tg4	578	38	)	)	-RRB-
cord-310847-63gh2tg4	578	39	.	.	.
cord-310847-63gh2tg4	579	1	The	the	DT
cord-310847-63gh2tg4	579	2	interaction	interaction	NN
cord-310847-63gh2tg4	579	3	between	between	IN
cord-310847-63gh2tg4	579	4	the	the	DT
cord-310847-63gh2tg4	579	5	PTP	PTP	NNP
cord-310847-63gh2tg4	579	6	-	-	HYPH
cord-310847-63gh2tg4	579	7	LYP	LYP	NNP
cord-310847-63gh2tg4	579	8	and	and	CC
cord-310847-63gh2tg4	579	9	Csk	Csk	NNP
cord-310847-63gh2tg4	579	10	is	be	VBZ
cord-310847-63gh2tg4	579	11	mediated	mediate	VBN
cord-310847-63gh2tg4	579	12	by	by	IN
cord-310847-63gh2tg4	579	13	the	the	DT
cord-310847-63gh2tg4	579	14	proline	proline	JJ
cord-310847-63gh2tg4	579	15	-	-	HYPH
cord-310847-63gh2tg4	579	16	rich	rich	JJ
cord-310847-63gh2tg4	579	17	motif	motif	NN
cord-310847-63gh2tg4	579	18	in	in	IN
cord-310847-63gh2tg4	579	19	PEP	pep	NN
cord-310847-63gh2tg4	579	20	and	and	CC
cord-310847-63gh2tg4	579	21	by	by	IN
cord-310847-63gh2tg4	579	22	the	the	DT
cord-310847-63gh2tg4	579	23	Src	Src	NNP
cord-310847-63gh2tg4	579	24	homology	homology	NN
cord-310847-63gh2tg4	579	25	3	3	CD
cord-310847-63gh2tg4	579	26	(	(	-LRB-
cord-310847-63gh2tg4	579	27	SH3	SH3	NNP
cord-310847-63gh2tg4	579	28	)	)	-RRB-
cord-310847-63gh2tg4	579	29	domain	domain	NN
cord-310847-63gh2tg4	579	30	of	of	IN
cord-310847-63gh2tg4	579	31	Csk	Csk	NNP
cord-310847-63gh2tg4	579	32	.	.	.
cord-310847-63gh2tg4	580	1	186	186	CD
cord-310847-63gh2tg4	580	2	PTP	PTP	NNP
cord-310847-63gh2tg4	580	3	-	-	HYPH
cord-310847-63gh2tg4	580	4	PEST	PEST	NNP
cord-310847-63gh2tg4	580	5	promiscuously	promiscuously	RB
cord-310847-63gh2tg4	580	6	associates	associate	VBZ
cord-310847-63gh2tg4	580	7	with	with	IN
cord-310847-63gh2tg4	580	8	various	various	JJ
cord-310847-63gh2tg4	580	9	proteins	protein	NNS
cord-310847-63gh2tg4	580	10	involved	involve	VBN
cord-310847-63gh2tg4	580	11	in	in	IN
cord-310847-63gh2tg4	580	12	the	the	DT
cord-310847-63gh2tg4	580	13	organization	organization	NN
cord-310847-63gh2tg4	580	14	of	of	IN
cord-310847-63gh2tg4	580	15	the	the	DT
cord-310847-63gh2tg4	580	16	cytoskeleton	cytoskeleton	NN
cord-310847-63gh2tg4	580	17	,	,	,
cord-310847-63gh2tg4	580	18	such	such	JJ
cord-310847-63gh2tg4	580	19	as	as	IN
cord-310847-63gh2tg4	580	20	Cas	Cas	NNP
cord-310847-63gh2tg4	580	21	(	(	-LRB-
cord-310847-63gh2tg4	580	22	and	and	CC
cord-310847-63gh2tg4	580	23	Cas	Cas	NNP
cord-310847-63gh2tg4	580	24	-	-	HYPH
cord-310847-63gh2tg4	580	25	related	relate	VBN
cord-310847-63gh2tg4	580	26	proteins	protein	NNS
cord-310847-63gh2tg4	580	27	Sin	sin	VBP
cord-310847-63gh2tg4	580	28	and	and	CC
cord-310847-63gh2tg4	580	29	CasL	CasL	NNP
cord-310847-63gh2tg4	580	30	)	)	-RRB-
cord-310847-63gh2tg4	580	31	,	,	,
cord-310847-63gh2tg4	580	32	paxillin	paxillin	NNP
cord-310847-63gh2tg4	580	33	(	(	-LRB-
cord-310847-63gh2tg4	580	34	and	and	CC
cord-310847-63gh2tg4	580	35	paxillin	paxillin	JJ
cord-310847-63gh2tg4	580	36	-	-	HYPH
cord-310847-63gh2tg4	580	37	related	relate	VBN
cord-310847-63gh2tg4	580	38	polypeptides	polypeptide	NNS
cord-310847-63gh2tg4	580	39	Hic-5	Hic-5	NNP
cord-310847-63gh2tg4	580	40	and	and	CC
cord-310847-63gh2tg4	580	41	leupaxin	leupaxin	NNP
cord-310847-63gh2tg4	580	42	)	)	-RRB-
cord-310847-63gh2tg4	580	43	and	and	CC
cord-310847-63gh2tg4	580	44	the	the	DT
cord-310847-63gh2tg4	580	45	PTKs	PTKs	NNP
cord-310847-63gh2tg4	580	46	FAK	FAK	NNP
cord-310847-63gh2tg4	580	47	and	and	CC
cord-310847-63gh2tg4	580	48	Pyk2	Pyk2	NNP
cord-310847-63gh2tg4	580	49	.	.	.
cord-310847-63gh2tg4	581	1	This	this	DT
cord-310847-63gh2tg4	581	2	protein	protein	NN
cord-310847-63gh2tg4	581	3	also	also	RB
cord-310847-63gh2tg4	581	4	associates	associate	VBZ
cord-310847-63gh2tg4	581	5	with	with	IN
cord-310847-63gh2tg4	581	6	Shc	Shc	NNP
cord-310847-63gh2tg4	581	7	,	,	,
cord-310847-63gh2tg4	581	8	Grb2	Grb2	NNP
cord-310847-63gh2tg4	581	9	and	and	CC
cord-310847-63gh2tg4	581	10	Csk	Csk	NNP
cord-310847-63gh2tg4	581	11	.	.	.
cord-310847-63gh2tg4	582	1	186	186	CD
cord-310847-63gh2tg4	583	1	Finally	finally	RB
cord-310847-63gh2tg4	583	2	,	,	,
cord-310847-63gh2tg4	583	3	PTP	PTP	NNP
cord-310847-63gh2tg4	583	4	-	-	HYPH
cord-310847-63gh2tg4	583	5	HSCF	HSCF	NNP
cord-310847-63gh2tg4	583	6	is	be	VBZ
cord-310847-63gh2tg4	583	7	involved	involve	VBN
cord-310847-63gh2tg4	583	8	in	in	IN
cord-310847-63gh2tg4	583	9	association	association	NN
cord-310847-63gh2tg4	583	10	with	with	IN
cord-310847-63gh2tg4	583	11	Csk	Csk	NNP
cord-310847-63gh2tg4	583	12	and	and	CC
cord-310847-63gh2tg4	583	13	Tec	Tec	NNP
cord-310847-63gh2tg4	583	14	.	.	.
cord-310847-63gh2tg4	584	1	186	186	CD
cord-310847-63gh2tg4	584	2	Multifarious	multifarious	JJ
cord-310847-63gh2tg4	584	3	functions	function	NNS
cord-310847-63gh2tg4	584	4	of	of	IN
cord-310847-63gh2tg4	584	5	glutamic	glutamic	NN
cord-310847-63gh2tg4	584	6	acid	acid	NN
cord-310847-63gh2tg4	584	7	-	-	HYPH
cord-310847-63gh2tg4	584	8	rich	rich	JJ
cord-310847-63gh2tg4	584	9	proteins	protein	NNS
cord-310847-63gh2tg4	584	10	.	.	.
cord-310847-63gh2tg4	585	1	Delta	Delta	NNP
cord-310847-63gh2tg4	585	2	factor	factor	NN
cord-310847-63gh2tg4	585	3	.	.	.
cord-310847-63gh2tg4	586	1	In	in	IN
cord-310847-63gh2tg4	586	2	addition	addition	NN
cord-310847-63gh2tg4	586	3	to	to	IN
cord-310847-63gh2tg4	586	4	γ	γ	NNP
cord-310847-63gh2tg4	586	5	-	-	:
cord-310847-63gh2tg4	586	6	PGA	PGA	NNP
cord-310847-63gh2tg4	586	7	,	,	,
cord-310847-63gh2tg4	586	8	Bacillus	bacillus	NN
cord-310847-63gh2tg4	586	9	subtilis	subtili	NNS
cord-310847-63gh2tg4	586	10	produces	produce	VBZ
cord-310847-63gh2tg4	586	11	another	another	DT
cord-310847-63gh2tg4	586	12	important	important	JJ
cord-310847-63gh2tg4	586	13	polyanion	polyanion	NN
cord-310847-63gh2tg4	586	14	,	,	,
cord-310847-63gh2tg4	586	15	delta	delta	NN
cord-310847-63gh2tg4	586	16	factor	factor	NN
cord-310847-63gh2tg4	586	17	,	,	,
cord-310847-63gh2tg4	586	18	which	which	WDT
cord-310847-63gh2tg4	586	19	is	be	VBZ
cord-310847-63gh2tg4	586	20	an	an	DT
cord-310847-63gh2tg4	586	21	important	important	JJ
cord-310847-63gh2tg4	586	22	component	component	NN
cord-310847-63gh2tg4	586	23	of	of	IN
cord-310847-63gh2tg4	586	24	the	the	DT
cord-310847-63gh2tg4	586	25	bacterial	bacterial	JJ
cord-310847-63gh2tg4	586	26	RNA	RNA	NNP
cord-310847-63gh2tg4	586	27	polymerase	polymerase	NN
cord-310847-63gh2tg4	586	28	.	.	.
cord-310847-63gh2tg4	587	1	188	188	CD
cord-310847-63gh2tg4	588	1	This	this	DT
cord-310847-63gh2tg4	588	2	delta	delta	NN
cord-310847-63gh2tg4	588	3	factor	factor	NN
cord-310847-63gh2tg4	588	4	is	be	VBZ
cord-310847-63gh2tg4	588	5	a	a	DT
cord-310847-63gh2tg4	588	6	20.4	20.4	CD
cord-310847-63gh2tg4	588	7	kDa	kDa	NNS
cord-310847-63gh2tg4	588	8	highly	highly	RB
cord-310847-63gh2tg4	588	9	acidic	acidic	JJ
cord-310847-63gh2tg4	588	10	(	(	-LRB-
cord-310847-63gh2tg4	588	11	pI	pi	NN
cord-310847-63gh2tg4	588	12	=	=	SYM
cord-310847-63gh2tg4	588	13	3.6	3.6	CD
cord-310847-63gh2tg4	588	14	)	)	-RRB-
cord-310847-63gh2tg4	588	15	protein	protein	NN
cord-310847-63gh2tg4	588	16	that	that	WDT
cord-310847-63gh2tg4	588	17	contains	contain	VBZ
cord-310847-63gh2tg4	588	18	two	two	CD
cord-310847-63gh2tg4	588	19	distinct	distinct	JJ
cord-310847-63gh2tg4	588	20	regions	region	NNS
cord-310847-63gh2tg4	588	21	,	,	,
cord-310847-63gh2tg4	588	22	a	a	DT
cord-310847-63gh2tg4	588	23	13	13	CD
cord-310847-63gh2tg4	588	24	kDa	kDa	NNP
cord-310847-63gh2tg4	588	25	N	n	CD
cord-310847-63gh2tg4	588	26	-	-	HYPH
cord-310847-63gh2tg4	588	27	terminal	terminal	NN
cord-310847-63gh2tg4	588	28	domain	domain	NN
cord-310847-63gh2tg4	588	29	with	with	IN
cord-310847-63gh2tg4	588	30	uniform	uniform	JJ
cord-310847-63gh2tg4	588	31	charge	charge	NN
cord-310847-63gh2tg4	588	32	distribution	distribution	NN
cord-310847-63gh2tg4	588	33	and	and	CC
cord-310847-63gh2tg4	588	34	a	a	DT
cord-310847-63gh2tg4	588	35	Glu	Glu	NNP
cord-310847-63gh2tg4	588	36	-	-	HYPH
cord-310847-63gh2tg4	588	37	Asp	Asp	NNP
cord-310847-63gh2tg4	588	38	-	-	HYPH
cord-310847-63gh2tg4	588	39	rich	rich	JJ
cord-310847-63gh2tg4	588	40	C	c	NN
cord-310847-63gh2tg4	588	41	-	-	HYPH
cord-310847-63gh2tg4	588	42	terminal	terminal	NN
cord-310847-63gh2tg4	588	43	region	region	NN
cord-310847-63gh2tg4	588	44	.	.	.
cord-310847-63gh2tg4	589	1	The	the	DT
cord-310847-63gh2tg4	589	2	overall	overall	JJ
cord-310847-63gh2tg4	589	3	contents	content	NNS
cord-310847-63gh2tg4	589	4	of	of	IN
cord-310847-63gh2tg4	589	5	glutamic	glutamic	NN
cord-310847-63gh2tg4	589	6	and	and	CC
cord-310847-63gh2tg4	589	7	aspartic	aspartic	JJ
cord-310847-63gh2tg4	589	8	acids	acid	NNS
cord-310847-63gh2tg4	589	9	in	in	IN
cord-310847-63gh2tg4	589	10	delta	delta	NN
cord-310847-63gh2tg4	589	11	factor	factor	NN
cord-310847-63gh2tg4	589	12	are	be	VBP
cord-310847-63gh2tg4	589	13	20.8	20.8	CD
cord-310847-63gh2tg4	589	14	%	%	NN
cord-310847-63gh2tg4	589	15	and	and	CC
cord-310847-63gh2tg4	589	16	17.9	17.9	CD
cord-310847-63gh2tg4	589	17	%	%	NN
cord-310847-63gh2tg4	589	18	respectively	respectively	RB
cord-310847-63gh2tg4	589	19	,	,	,
cord-310847-63gh2tg4	589	20	whereas	whereas	IN
cord-310847-63gh2tg4	589	21	these	these	DT
cord-310847-63gh2tg4	589	22	numbers	number	NNS
cord-310847-63gh2tg4	589	23	increase	increase	VBP
cord-310847-63gh2tg4	589	24	to	to	IN
cord-310847-63gh2tg4	589	25	34.3	34.3	CD
cord-310847-63gh2tg4	589	26	%	%	NN
cord-310847-63gh2tg4	589	27	and	and	CC
cord-310847-63gh2tg4	589	28	37.3	37.3	CD
cord-310847-63gh2tg4	589	29	%	%	NN
cord-310847-63gh2tg4	589	30	in	in	IN
cord-310847-63gh2tg4	589	31	the	the	DT
cord-310847-63gh2tg4	589	32	Glu	Glu	NNP
cord-310847-63gh2tg4	589	33	-	-	HYPH
cord-310847-63gh2tg4	589	34	Asp	Asp	NNP
cord-310847-63gh2tg4	589	35	-	-	HYPH
cord-310847-63gh2tg4	589	36	rich	rich	JJ
cord-310847-63gh2tg4	589	37	C	c	NN
cord-310847-63gh2tg4	589	38	-	-	HYPH
cord-310847-63gh2tg4	589	39	terminal	terminal	NN
cord-310847-63gh2tg4	589	40	domain	domain	NN
cord-310847-63gh2tg4	589	41	.	.	.
cord-310847-63gh2tg4	590	1	The	the	DT
cord-310847-63gh2tg4	590	2	ordered	order	VBN
cord-310847-63gh2tg4	590	3	N	n	CD
cord-310847-63gh2tg4	590	4	-	-	HYPH
cord-310847-63gh2tg4	590	5	terminal	terminal	NN
cord-310847-63gh2tg4	590	6	domain	domain	NN
cord-310847-63gh2tg4	590	7	contains	contain	VBZ
cord-310847-63gh2tg4	590	8	32	32	CD
cord-310847-63gh2tg4	590	9	%	%	NN
cord-310847-63gh2tg4	590	10	α	α	NN
cord-310847-63gh2tg4	590	11	-	-	HYPH
cord-310847-63gh2tg4	590	12	helix	helix	NN
cord-310847-63gh2tg4	590	13	and	and	CC
cord-310847-63gh2tg4	590	14	16	16	CD
cord-310847-63gh2tg4	590	15	%	%	NN
cord-310847-63gh2tg4	590	16	β	β	NN
cord-310847-63gh2tg4	590	17	-	-	HYPH
cord-310847-63gh2tg4	590	18	sheet	sheet	NN
cord-310847-63gh2tg4	590	19	,	,	,
cord-310847-63gh2tg4	590	20	whereas	whereas	IN
cord-310847-63gh2tg4	590	21	the	the	DT
cord-310847-63gh2tg4	590	22	C	C	NNP
cord-310847-63gh2tg4	590	23	-	-	HYPH
cord-310847-63gh2tg4	590	24	terminal	terminal	NN
cord-310847-63gh2tg4	590	25	8.5	8.5	CD
cord-310847-63gh2tg4	590	26	kDa	kDa	NNP
cord-310847-63gh2tg4	590	27	domain	domain	NN
cord-310847-63gh2tg4	590	28	is	be	VBZ
cord-310847-63gh2tg4	590	29	highly	highly	RB
cord-310847-63gh2tg4	590	30	charged	charge	VBN
cord-310847-63gh2tg4	590	31	(	(	-LRB-
cord-310847-63gh2tg4	590	32	net	net	JJ
cord-310847-63gh2tg4	590	33	charge	charge	NN
cord-310847-63gh2tg4	590	34	of	of	IN
cord-310847-63gh2tg4	590	35	−47	−47	NNP
cord-310847-63gh2tg4	590	36	)	)	-RRB-
cord-310847-63gh2tg4	590	37	and	and	CC
cord-310847-63gh2tg4	590	38	therefore	therefore	RB
cord-310847-63gh2tg4	590	39	is	be	VBZ
cord-310847-63gh2tg4	590	40	largely	largely	RB
cord-310847-63gh2tg4	590	41	unstructured	unstructured	JJ
cord-310847-63gh2tg4	590	42	.	.	.
cord-310847-63gh2tg4	591	1	188	188	CD
cord-310847-63gh2tg4	592	1	Importantly	importantly	RB
cord-310847-63gh2tg4	592	2	,	,	,
cord-310847-63gh2tg4	592	3	the	the	DT
cord-310847-63gh2tg4	592	4	C	c	NN
cord-310847-63gh2tg4	592	5	-	-	HYPH
cord-310847-63gh2tg4	592	6	terminal	terminal	NN
cord-310847-63gh2tg4	592	7	intrinsically	intrinsically	RB
cord-310847-63gh2tg4	592	8	disordered	disordered	JJ
cord-310847-63gh2tg4	592	9	domain	domain	NN
cord-310847-63gh2tg4	592	10	has	have	VBZ
cord-310847-63gh2tg4	592	11	an	an	DT
cord-310847-63gh2tg4	592	12	important	important	JJ
cord-310847-63gh2tg4	592	13	biological	biological	JJ
cord-310847-63gh2tg4	592	14	function	function	NN
cord-310847-63gh2tg4	592	15	,	,	,
cord-310847-63gh2tg4	592	16	since	since	IN
cord-310847-63gh2tg4	592	17	the	the	DT
cord-310847-63gh2tg4	592	18	ability	ability	NN
cord-310847-63gh2tg4	592	19	of	of	IN
cord-310847-63gh2tg4	592	20	delta	delta	NN
cord-310847-63gh2tg4	592	21	factor	factor	NN
cord-310847-63gh2tg4	592	22	to	to	TO
cord-310847-63gh2tg4	592	23	displace	displace	VB
cord-310847-63gh2tg4	592	24	RNA	RNA	NNP
cord-310847-63gh2tg4	592	25	from	from	IN
cord-310847-63gh2tg4	592	26	RNA	RNA	NNP
cord-310847-63gh2tg4	592	27	polymerase	polymerase	NN
cord-310847-63gh2tg4	592	28	requires	require	VBZ
cord-310847-63gh2tg4	592	29	the	the	DT
cord-310847-63gh2tg4	592	30	activities	activity	NNS
cord-310847-63gh2tg4	592	31	of	of	IN
cord-310847-63gh2tg4	592	32	both	both	CC
cord-310847-63gh2tg4	592	33	the	the	DT
cord-310847-63gh2tg4	592	34	N	n	CD
cord-310847-63gh2tg4	592	35	-	-	HYPH
cord-310847-63gh2tg4	592	36	terminal	terminal	NN
cord-310847-63gh2tg4	592	37	core	core	NN
cord-310847-63gh2tg4	592	38	-	-	HYPH
cord-310847-63gh2tg4	592	39	binding	bind	VBG
cord-310847-63gh2tg4	592	40	domain	domain	NN
cord-310847-63gh2tg4	592	41	and	and	CC
cord-310847-63gh2tg4	592	42	the	the	DT
cord-310847-63gh2tg4	592	43	polyanionic	polyanionic	NNP
cord-310847-63gh2tg4	592	44	C	C	NNP
cord-310847-63gh2tg4	592	45	-	-	HYPH
cord-310847-63gh2tg4	592	46	terminal	terminal	NN
cord-310847-63gh2tg4	592	47	region	region	NN
cord-310847-63gh2tg4	592	48	.	.	.
cord-310847-63gh2tg4	593	1	188	188	CD
cord-310847-63gh2tg4	593	2	MARCKS	marck	NNS
cord-310847-63gh2tg4	593	3	.	.	.
cord-310847-63gh2tg4	594	1	Myristoylated	Myristoylated	NNP
cord-310847-63gh2tg4	594	2	alanine	alanine	NN
cord-310847-63gh2tg4	594	3	-	-	HYPH
cord-310847-63gh2tg4	594	4	rich	rich	JJ
cord-310847-63gh2tg4	594	5	C	c	NN
cord-310847-63gh2tg4	594	6	kinase	kinase	NN
cord-310847-63gh2tg4	594	7	substrate	substrate	NN
cord-310847-63gh2tg4	594	8	(	(	-LRB-
cord-310847-63gh2tg4	594	9	MARCKS	MARCKS	NNP
cord-310847-63gh2tg4	594	10	)	)	-RRB-
cord-310847-63gh2tg4	594	11	is	be	VBZ
cord-310847-63gh2tg4	594	12	an	an	DT
cord-310847-63gh2tg4	594	13	abundant	abundant	JJ
cord-310847-63gh2tg4	594	14	32	32	CD
cord-310847-63gh2tg4	594	15	kDa	kda	NN
cord-310847-63gh2tg4	594	16	protein	protein	NN
cord-310847-63gh2tg4	594	17	which	which	WDT
cord-310847-63gh2tg4	594	18	is	be	VBZ
cord-310847-63gh2tg4	594	19	unusually	unusually	RB
cord-310847-63gh2tg4	594	20	rich	rich	JJ
cord-310847-63gh2tg4	594	21	in	in	IN
cord-310847-63gh2tg4	594	22	alanine	alanine	NN
cord-310847-63gh2tg4	594	23	and	and	CC
cord-310847-63gh2tg4	594	24	glutamic	glutamic	NN
cord-310847-63gh2tg4	594	25	acid	acid	NN
cord-310847-63gh2tg4	594	26	,	,	,
cord-310847-63gh2tg4	594	27	with	with	IN
cord-310847-63gh2tg4	594	28	glutamic	glutamic	NN
cord-310847-63gh2tg4	594	29	acid	acid	NN
cord-310847-63gh2tg4	594	30	and	and	CC
cord-310847-63gh2tg4	594	31	alanine	alanine	NN
cord-310847-63gh2tg4	594	32	in	in	IN
cord-310847-63gh2tg4	594	33	this	this	DT
cord-310847-63gh2tg4	594	34	proteins	protein	NNS
cord-310847-63gh2tg4	594	35	accounting	account	VBG
cord-310847-63gh2tg4	594	36	for	for	IN
cord-310847-63gh2tg4	594	37	16.0	16.0	CD
cord-310847-63gh2tg4	594	38	%	%	NN
cord-310847-63gh2tg4	594	39	and	and	CC
cord-310847-63gh2tg4	594	40	30.7	30.7	CD
cord-310847-63gh2tg4	594	41	%	%	NN
cord-310847-63gh2tg4	594	42	residues	residue	NNS
cord-310847-63gh2tg4	594	43	,	,	,
cord-310847-63gh2tg4	594	44	respectively	respectively	RB
cord-310847-63gh2tg4	594	45	.	.	.
cord-310847-63gh2tg4	595	1	MARCKS	MARCKS	NNP
cord-310847-63gh2tg4	595	2	is	be	VBZ
cord-310847-63gh2tg4	595	3	a	a	DT
cord-310847-63gh2tg4	595	4	very	very	RB
cord-310847-63gh2tg4	595	5	prominent	prominent	JJ
cord-310847-63gh2tg4	595	6	cellular	cellular	JJ
cord-310847-63gh2tg4	595	7	substrate	substrate	NN
cord-310847-63gh2tg4	595	8	for	for	IN
cord-310847-63gh2tg4	595	9	protein	protein	NN
cord-310847-63gh2tg4	595	10	kinase	kinase	NN
cord-310847-63gh2tg4	595	11	C	C	NNP
cord-310847-63gh2tg4	595	12	(	(	-LRB-
cord-310847-63gh2tg4	595	13	PKC	PKC	NNP
cord-310847-63gh2tg4	595	14	)	)	-RRB-
cord-310847-63gh2tg4	595	15	,	,	,
cord-310847-63gh2tg4	595	16	and	and	CC
cord-310847-63gh2tg4	595	17	its	-PRON-	PRP$
cord-310847-63gh2tg4	595	18	22	22	CD
cord-310847-63gh2tg4	595	19	serine	serine	NN
cord-310847-63gh2tg4	595	20	residues	residue	NNS
cord-310847-63gh2tg4	595	21	and	and	CC
cord-310847-63gh2tg4	595	22	2	2	CD
cord-310847-63gh2tg4	595	23	threonines	threonine	NNS
cord-310847-63gh2tg4	595	24	are	be	VBP
cord-310847-63gh2tg4	595	25	phosphorylated	phosphorylate	VBN
cord-310847-63gh2tg4	595	26	.	.	.
cord-310847-63gh2tg4	596	1	Human	Human	NNP
cord-310847-63gh2tg4	596	2	MARCKS	MARCKS	NNP
cord-310847-63gh2tg4	596	3	is	be	VBZ
cord-310847-63gh2tg4	596	4	an	an	DT
cord-310847-63gh2tg4	596	5	acidic	acidic	JJ
cord-310847-63gh2tg4	596	6	protein	protein	NN
cord-310847-63gh2tg4	596	7	with	with	IN
cord-310847-63gh2tg4	596	8	a	a	DT
cord-310847-63gh2tg4	596	9	pI	pi	NN
cord-310847-63gh2tg4	596	10	of	of	IN
cord-310847-63gh2tg4	596	11	4.46	4.46	CD
cord-310847-63gh2tg4	596	12	which	which	WDT
cord-310847-63gh2tg4	596	13	in	in	IN
cord-310847-63gh2tg4	596	14	addition	addition	NN
cord-310847-63gh2tg4	596	15	to	to	IN
cord-310847-63gh2tg4	596	16	Ala	Ala	NNP
cord-310847-63gh2tg4	596	17	-	-	HYPH
cord-310847-63gh2tg4	596	18	Glu	Glu	NNP
cord-310847-63gh2tg4	596	19	enriched	enrich	VBD
cord-310847-63gh2tg4	596	20	N	N	NNP
cord-310847-63gh2tg4	596	21	-	-	HYPH
cord-310847-63gh2tg4	596	22	and	and	CC
cord-310847-63gh2tg4	596	23	C	c	NN
cord-310847-63gh2tg4	596	24	-	-	HYPH
cord-310847-63gh2tg4	596	25	terminal	terminal	NN
cord-310847-63gh2tg4	596	26	domains	domain	NNS
cord-310847-63gh2tg4	596	27	possesses	possess	VBZ
cord-310847-63gh2tg4	596	28	a	a	DT
cord-310847-63gh2tg4	596	29	compact	compact	JJ
cord-310847-63gh2tg4	596	30	"	"	``
cord-310847-63gh2tg4	596	31	effector	effector	NN
cord-310847-63gh2tg4	596	32	domain	domain	NN
cord-310847-63gh2tg4	596	33	"	"	''
cord-310847-63gh2tg4	596	34	(	(	-LRB-
cord-310847-63gh2tg4	596	35	ED	ED	NNP
cord-310847-63gh2tg4	596	36	)	)	-RRB-
cord-310847-63gh2tg4	596	37	,	,	,
cord-310847-63gh2tg4	596	38	which	which	WDT
cord-310847-63gh2tg4	596	39	is	be	VBZ
cord-310847-63gh2tg4	596	40	responsible	responsible	JJ
cord-310847-63gh2tg4	596	41	for	for	IN
cord-310847-63gh2tg4	596	42	interaction	interaction	NN
cord-310847-63gh2tg4	596	43	with	with	IN
cord-310847-63gh2tg4	596	44	calmodulin	calmodulin	NN
cord-310847-63gh2tg4	596	45	,	,	,
cord-310847-63gh2tg4	596	46	is	be	VBZ
cord-310847-63gh2tg4	596	47	located	locate	VBN
cord-310847-63gh2tg4	596	48	near	near	IN
cord-310847-63gh2tg4	596	49	the	the	DT
cord-310847-63gh2tg4	596	50	middle	middle	NN
cord-310847-63gh2tg4	596	51	of	of	IN
cord-310847-63gh2tg4	596	52	the	the	DT
cord-310847-63gh2tg4	596	53	sequence	sequence	NN
cord-310847-63gh2tg4	596	54	and	and	CC
cord-310847-63gh2tg4	596	55	is	be	VBZ
cord-310847-63gh2tg4	596	56	enriched	enrich	VBN
cord-310847-63gh2tg4	596	57	in	in	IN
cord-310847-63gh2tg4	596	58	lysines	lysine	NNS
cord-310847-63gh2tg4	596	59	,	,	,
cord-310847-63gh2tg4	596	60	serines	serines	NNPS
cord-310847-63gh2tg4	596	61	and	and	CC
cord-310847-63gh2tg4	596	62	phenylalanines	phenylalanines	NNP
cord-310847-63gh2tg4	596	63	.	.	.
cord-310847-63gh2tg4	597	1	189	189	CD
cord-310847-63gh2tg4	597	2	MARCKS	MARCKS	NNP
cord-310847-63gh2tg4	597	3	is	be	VBZ
cord-310847-63gh2tg4	597	4	a	a	DT
cord-310847-63gh2tg4	597	5	typical	typical	JJ
cord-310847-63gh2tg4	597	6	IDP	IDP	NNP
cord-310847-63gh2tg4	597	7	with	with	IN
cord-310847-63gh2tg4	597	8	a	a	DT
cord-310847-63gh2tg4	597	9	labile	labile	JJ
cord-310847-63gh2tg4	597	10	conformation	conformation	NN
cord-310847-63gh2tg4	597	11	and	and	CC
cord-310847-63gh2tg4	597	12	little	little	JJ
cord-310847-63gh2tg4	597	13	ordered	order	VBN
cord-310847-63gh2tg4	597	14	structure	structure	NN
cord-310847-63gh2tg4	597	15	.	.	.
cord-310847-63gh2tg4	598	1	In	in	IN
cord-310847-63gh2tg4	598	2	addition	addition	NN
cord-310847-63gh2tg4	598	3	to	to	IN
cord-310847-63gh2tg4	598	4	calmodulin	calmodulin	NNP
cord-310847-63gh2tg4	599	1	this	this	DT
cord-310847-63gh2tg4	599	2	protein	protein	NN
cord-310847-63gh2tg4	599	3	can	can	MD
cord-310847-63gh2tg4	599	4	interact	interact	VB
cord-310847-63gh2tg4	599	5	with	with	IN
cord-310847-63gh2tg4	599	6	synapsin	synapsin	NNP
cord-310847-63gh2tg4	599	7	and	and	CC
cord-310847-63gh2tg4	599	8	actin	actin	NN
cord-310847-63gh2tg4	599	9	,	,	,
cord-310847-63gh2tg4	599	10	and	and	CC
cord-310847-63gh2tg4	599	11	can	can	MD
cord-310847-63gh2tg4	599	12	serve	serve	VB
cord-310847-63gh2tg4	599	13	as	as	IN
cord-310847-63gh2tg4	599	14	filamentous	filamentous	JJ
cord-310847-63gh2tg4	599	15	actin	actin	NN
cord-310847-63gh2tg4	599	16	(	(	-LRB-
cord-310847-63gh2tg4	599	17	F	F	NNP
cord-310847-63gh2tg4	599	18	-	-	HYPH
cord-310847-63gh2tg4	599	19	actin	actin	NNP
cord-310847-63gh2tg4	599	20	)	)	-RRB-
cord-310847-63gh2tg4	599	21	cross	cross	JJ
cord-310847-63gh2tg4	599	22	-	-	JJ
cord-310847-63gh2tg4	599	23	linking	link	VBG
cord-310847-63gh2tg4	599	24	protein	protein	NN
cord-310847-63gh2tg4	599	25	.	.	.
cord-310847-63gh2tg4	600	1	Furthermore	furthermore	RB
cord-310847-63gh2tg4	600	2	,	,	,
cord-310847-63gh2tg4	600	3	being	be	VBG
cord-310847-63gh2tg4	600	4	myristoylated	myristoylate	VBN
cord-310847-63gh2tg4	600	5	,	,	,
cord-310847-63gh2tg4	600	6	MARCKS	MARCKS	NNP
cord-310847-63gh2tg4	600	7	is	be	VBZ
cord-310847-63gh2tg4	600	8	able	able	JJ
cord-310847-63gh2tg4	600	9	to	to	TO
cord-310847-63gh2tg4	600	10	interact	interact	VB
cord-310847-63gh2tg4	600	11	with	with	IN
cord-310847-63gh2tg4	600	12	membrane	membrane	NN
cord-310847-63gh2tg4	600	13	and	and	CC
cord-310847-63gh2tg4	600	14	serves	serve	VBZ
cord-310847-63gh2tg4	600	15	as	as	IN
cord-310847-63gh2tg4	600	16	a	a	DT
cord-310847-63gh2tg4	600	17	cytoskeleton	cytoskeleton	NN
cord-310847-63gh2tg4	600	18	-	-	HYPH
cord-310847-63gh2tg4	600	19	membrane	membrane	NN
cord-310847-63gh2tg4	600	20	linkage	linkage	NN
cord-310847-63gh2tg4	600	21	crucial	crucial	JJ
cord-310847-63gh2tg4	600	22	for	for	IN
cord-310847-63gh2tg4	600	23	controlling	control	VBG
cord-310847-63gh2tg4	600	24	cell	cell	NN
cord-310847-63gh2tg4	600	25	shape	shape	NN
cord-310847-63gh2tg4	600	26	changes	change	NNS
cord-310847-63gh2tg4	600	27	.	.	.
cord-310847-63gh2tg4	601	1	189	189	CD
cord-310847-63gh2tg4	601	2	since	since	IN
cord-310847-63gh2tg4	601	3	although	although	IN
cord-310847-63gh2tg4	601	4	the	the	DT
cord-310847-63gh2tg4	601	5	molecular	molecular	JJ
cord-310847-63gh2tg4	601	6	mass	mass	NN
cord-310847-63gh2tg4	601	7	of	of	IN
cord-310847-63gh2tg4	601	8	the	the	DT
cord-310847-63gh2tg4	601	9	phosphoprotein	phosphoprotein	NN
cord-310847-63gh2tg4	601	10	was	be	VBD
cord-310847-63gh2tg4	601	11	shown	show	VBN
cord-310847-63gh2tg4	601	12	to	to	TO
cord-310847-63gh2tg4	601	13	be	be	VB
cord-310847-63gh2tg4	601	14	about	about	RB
cord-310847-63gh2tg4	601	15	44	44	CD
cord-310847-63gh2tg4	601	16	kDa	kDa	NNS
cord-310847-63gh2tg4	601	17	by	by	IN
cord-310847-63gh2tg4	601	18	sedimentation	sedimentation	NN
cord-310847-63gh2tg4	601	19	equilibrium	equilibrium	NNP
cord-310847-63gh2tg4	601	20	analysis	analysis	NN
cord-310847-63gh2tg4	601	21	,	,	,
cord-310847-63gh2tg4	601	22	it	-PRON-	PRP
cord-310847-63gh2tg4	601	23	runs	run	VBZ
cord-310847-63gh2tg4	601	24	on	on	IN
cord-310847-63gh2tg4	601	25	5	5	CD
cord-310847-63gh2tg4	601	26	-	-	SYM
cord-310847-63gh2tg4	601	27	15	15	CD
cord-310847-63gh2tg4	601	28	%	%	NN
cord-310847-63gh2tg4	601	29	SDS	SDS	NNP
cord-310847-63gh2tg4	601	30	-	-	HYPH
cord-310847-63gh2tg4	601	31	PAGE	PAGE	NNP
cord-310847-63gh2tg4	601	32	(	(	-LRB-
cord-310847-63gh2tg4	601	33	SDS	SDS	NNP
cord-310847-63gh2tg4	601	34	-	-	HYPH
cord-310847-63gh2tg4	601	35	PAGE	PAGE	NNP
cord-310847-63gh2tg4	601	36	)	)	-RRB-
cord-310847-63gh2tg4	601	37	as	as	IN
cord-310847-63gh2tg4	601	38	a	a	DT
cord-310847-63gh2tg4	601	39	protein	protein	NN
cord-310847-63gh2tg4	601	40	with	with	IN
cord-310847-63gh2tg4	601	41	a	a	DT
cord-310847-63gh2tg4	601	42	molecular	molecular	JJ
cord-310847-63gh2tg4	601	43	mass	mass	NN
cord-310847-63gh2tg4	601	44	of	of	IN
cord-310847-63gh2tg4	601	45	75	75	CD
cord-310847-63gh2tg4	601	46	kDa	kDa	NNS
cord-310847-63gh2tg4	601	47	.	.	.
cord-310847-63gh2tg4	602	1	197	197	CD
cord-310847-63gh2tg4	603	1	Later	Later	NNP
cord-310847-63gh2tg4	603	2	studies	study	NNS
cord-310847-63gh2tg4	603	3	revealed	reveal	VBD
cord-310847-63gh2tg4	603	4	that	that	IN
cord-310847-63gh2tg4	603	5	BSP	BSP	NNP
cord-310847-63gh2tg4	603	6	is	be	VBZ
cord-310847-63gh2tg4	603	7	capable	capable	JJ
cord-310847-63gh2tg4	603	8	of	of	IN
cord-310847-63gh2tg4	603	9	nucleating	nucleate	VBG
cord-310847-63gh2tg4	603	10	the	the	DT
cord-310847-63gh2tg4	603	11	bone	bone	NN
cord-310847-63gh2tg4	603	12	mineral	mineral	NN
cord-310847-63gh2tg4	603	13	hydroxyapatite	hydroxyapatite	NN
cord-310847-63gh2tg4	603	14	and	and	CC
cord-310847-63gh2tg4	603	15	that	that	IN
cord-310847-63gh2tg4	603	16	this	this	DT
cord-310847-63gh2tg4	603	17	nucleation	nucleation	NN
cord-310847-63gh2tg4	603	18	involves	involve	VBZ
cord-310847-63gh2tg4	603	19	one	one	CD
cord-310847-63gh2tg4	603	20	or	or	CC
cord-310847-63gh2tg4	603	21	both	both	DT
cord-310847-63gh2tg4	603	22	of	of	IN
cord-310847-63gh2tg4	603	23	the	the	DT
cord-310847-63gh2tg4	603	24	glutamic	glutamic	NN
cord-310847-63gh2tg4	603	25	acid	acid	NN
cord-310847-63gh2tg4	603	26	-	-	HYPH
cord-310847-63gh2tg4	603	27	rich	rich	JJ
cord-310847-63gh2tg4	603	28	sequences	sequence	NNS
cord-310847-63gh2tg4	603	29	suggesting	suggest	VBG
cord-310847-63gh2tg4	603	30	that	that	IN
cord-310847-63gh2tg4	603	31	polycarboxylate	polycarboxylate	NNP
cord-310847-63gh2tg4	603	32	sequences	sequence	NNS
cord-310847-63gh2tg4	603	33	might	may	MD
cord-310847-63gh2tg4	603	34	represent	represent	VB
cord-310847-63gh2tg4	603	35	a	a	DT
cord-310847-63gh2tg4	603	36	specific	specific	JJ
cord-310847-63gh2tg4	603	37	site	site	NN
cord-310847-63gh2tg4	603	38	for	for	IN
cord-310847-63gh2tg4	603	39	growth	growth	NN
cord-310847-63gh2tg4	603	40	-	-	HYPH
cord-310847-63gh2tg4	603	41	modulating	modulate	VBG
cord-310847-63gh2tg4	603	42	interactions	interaction	NNS
cord-310847-63gh2tg4	603	43	between	between	IN
cord-310847-63gh2tg4	603	44	proteins	protein	NNS
cord-310847-63gh2tg4	603	45	and	and	CC
cord-310847-63gh2tg4	603	46	biological	biological	JJ
cord-310847-63gh2tg4	603	47	hydroxyapatite	hydroxyapatite	NN
cord-310847-63gh2tg4	603	48	crystals	crystal	NNS
cord-310847-63gh2tg4	603	49	.	.	.
cord-310847-63gh2tg4	604	1	198	198	CD
cord-310847-63gh2tg4	605	1	Similarly	similarly	RB
cord-310847-63gh2tg4	605	2	,	,	,
cord-310847-63gh2tg4	605	3	the	the	DT
cord-310847-63gh2tg4	605	4	ability	ability	NN
cord-310847-63gh2tg4	605	5	of	of	IN
cord-310847-63gh2tg4	605	6	another	another	DT
cord-310847-63gh2tg4	605	7	acidic	acidic	JJ
cord-310847-63gh2tg4	605	8	,	,	,
cord-310847-63gh2tg4	605	9	non	non	JJ
cord-310847-63gh2tg4	605	10	-	-	JJ
cord-310847-63gh2tg4	605	11	collagenous	collagenous	JJ
cord-310847-63gh2tg4	605	12	protein	protein	NN
cord-310847-63gh2tg4	605	13	of	of	IN
cord-310847-63gh2tg4	605	14	bone	bone	NN
cord-310847-63gh2tg4	605	15	and	and	CC
cord-310847-63gh2tg4	605	16	dentin	dentin	NN
cord-310847-63gh2tg4	605	17	,	,	,
cord-310847-63gh2tg4	605	18	osteonectin	osteonectin	NNPS
cord-310847-63gh2tg4	605	19	(	(	-LRB-
cord-310847-63gh2tg4	605	20	also	also	RB
cord-310847-63gh2tg4	605	21	known	know	VBN
cord-310847-63gh2tg4	605	22	as	as	IN
cord-310847-63gh2tg4	605	23	secreted	secrete	VBN
cord-310847-63gh2tg4	605	24	protein	protein	NN
cord-310847-63gh2tg4	605	25	,	,	,
cord-310847-63gh2tg4	605	26	acidic	acidic	JJ
cord-310847-63gh2tg4	605	27	,	,	,
cord-310847-63gh2tg4	605	28	rich	rich	JJ
cord-310847-63gh2tg4	605	29	in	in	IN
cord-310847-63gh2tg4	605	30	cysteine	cysteine	NN
cord-310847-63gh2tg4	605	31	)	)	-RRB-
cord-310847-63gh2tg4	605	32	,	,	,
cord-310847-63gh2tg4	605	33	to	to	TO
cord-310847-63gh2tg4	605	34	bind	bind	VB
cord-310847-63gh2tg4	605	35	to	to	IN
cord-310847-63gh2tg4	605	36	hydroxyapatite	hydroxyapatite	JJ
cord-310847-63gh2tg4	605	37	crystals	crystal	NNS
cord-310847-63gh2tg4	605	38	is	be	VBZ
cord-310847-63gh2tg4	605	39	determined	determine	VBN
cord-310847-63gh2tg4	605	40	by	by	IN
cord-310847-63gh2tg4	605	41	its	-PRON-	PRP$
cord-310847-63gh2tg4	605	42	N	n	CD
cord-310847-63gh2tg4	605	43	-	-	HYPH
cord-310847-63gh2tg4	605	44	terminal	terminal	NN
cord-310847-63gh2tg4	605	45	region	region	NN
cord-310847-63gh2tg4	605	46	containing	contain	VBG
cord-310847-63gh2tg4	605	47	glutamic	glutamic	NN
cord-310847-63gh2tg4	605	48	acid	acid	NN
cord-310847-63gh2tg4	605	49	-	-	HYPH
cord-310847-63gh2tg4	605	50	rich	rich	JJ
cord-310847-63gh2tg4	605	51	sequences	sequence	NNS
cord-310847-63gh2tg4	605	52	.	.	.
cord-310847-63gh2tg4	606	1	199	199	CD
cord-310847-63gh2tg4	606	2	SPARC	SPARC	NNP
cord-310847-63gh2tg4	606	3	is	be	VBZ
cord-310847-63gh2tg4	606	4	a	a	DT
cord-310847-63gh2tg4	606	5	highly	highly	RB
cord-310847-63gh2tg4	606	6	conserved	conserved	JJ
cord-310847-63gh2tg4	606	7	acidic	acidic	JJ
cord-310847-63gh2tg4	606	8	calcium	calcium	NN
cord-310847-63gh2tg4	606	9	-	-	HYPH
cord-310847-63gh2tg4	606	10	binding	bind	VBG
cord-310847-63gh2tg4	606	11	extracellular	extracellular	JJ
cord-310847-63gh2tg4	606	12	-	-	HYPH
cord-310847-63gh2tg4	606	13	matrix	matrix	NN
cord-310847-63gh2tg4	606	14	protein	protein	NN
cord-310847-63gh2tg4	606	15	.	.	.
cord-310847-63gh2tg4	607	1	200	200	CD
cord-310847-63gh2tg4	608	1	This	this	DT
cord-310847-63gh2tg4	608	2	matricellular	matricellular	JJ
cord-310847-63gh2tg4	608	3	glycoprotein	glycoprotein	NN
cord-310847-63gh2tg4	608	4	is	be	VBZ
cord-310847-63gh2tg4	608	5	composed	compose	VBN
cord-310847-63gh2tg4	608	6	of	of	IN
cord-310847-63gh2tg4	608	7	three	three	CD
cord-310847-63gh2tg4	608	8	functional	functional	JJ
cord-310847-63gh2tg4	608	9	domains	domain	NNS
cord-310847-63gh2tg4	608	10	that	that	WDT
cord-310847-63gh2tg4	608	11	are	be	VBP
cord-310847-63gh2tg4	608	12	evolutionarily	evolutionarily	RB
cord-310847-63gh2tg4	608	13	conserved	conserve	VBN
cord-310847-63gh2tg4	608	14	in	in	IN
cord-310847-63gh2tg4	608	15	organisms	organism	NNS
cord-310847-63gh2tg4	608	16	ranging	range	VBG
cord-310847-63gh2tg4	608	17	from	from	IN
cord-310847-63gh2tg4	608	18	nematodes	nematode	NNS
cord-310847-63gh2tg4	608	19	to	to	IN
cord-310847-63gh2tg4	608	20	mammals	mammal	NNS
cord-310847-63gh2tg4	608	21	.	.	.
cord-310847-63gh2tg4	609	1	201	201	CD
cord-310847-63gh2tg4	610	1	Starting	start	VBG
cord-310847-63gh2tg4	610	2	from	from	IN
cord-310847-63gh2tg4	610	3	the	the	DT
cord-310847-63gh2tg4	610	4	N	n	CD
cord-310847-63gh2tg4	610	5	-	-	HYPH
cord-310847-63gh2tg4	610	6	terminus	terminus	NN
cord-310847-63gh2tg4	610	7	,	,	,
cord-310847-63gh2tg4	610	8	these	these	DT
cord-310847-63gh2tg4	610	9	functional	functional	JJ
cord-310847-63gh2tg4	610	10	domains	domain	NNS
cord-310847-63gh2tg4	610	11	are	be	VBP
cord-310847-63gh2tg4	610	12	:	:	:
cord-310847-63gh2tg4	610	13	a	a	DT
cord-310847-63gh2tg4	610	14	Ca	Ca	NNP
cord-310847-63gh2tg4	610	15	2	2	CD
cord-310847-63gh2tg4	610	16	+	+	SYM
cord-310847-63gh2tg4	610	17	-binding	-binde	VBG
cord-310847-63gh2tg4	610	18	glutamic	glutamic	NN
cord-310847-63gh2tg4	610	19	acid	acid	NN
cord-310847-63gh2tg4	610	20	-	-	HYPH
cord-310847-63gh2tg4	610	21	rich	rich	JJ
cord-310847-63gh2tg4	610	22	acidic	acidic	JJ
cord-310847-63gh2tg4	610	23	domain	domain	NN
cord-310847-63gh2tg4	610	24	(	(	-LRB-
cord-310847-63gh2tg4	610	25	domain	domain	NN
cord-310847-63gh2tg4	610	26	I	I	NNP
cord-310847-63gh2tg4	610	27	)	)	-RRB-
cord-310847-63gh2tg4	610	28	,	,	,
cord-310847-63gh2tg4	610	29	a	a	DT
cord-310847-63gh2tg4	610	30	follistatin	follistatin	NN
cord-310847-63gh2tg4	610	31	-	-	HYPH
cord-310847-63gh2tg4	610	32	like	like	JJ
cord-310847-63gh2tg4	610	33	module	module	NN
cord-310847-63gh2tg4	610	34	(	(	-LRB-
cord-310847-63gh2tg4	610	35	domain	domain	NN
cord-310847-63gh2tg4	610	36	II	II	NNP
cord-310847-63gh2tg4	610	37	)	)	-RRB-
cord-310847-63gh2tg4	610	38	,	,	,
cord-310847-63gh2tg4	610	39	and	and	CC
cord-310847-63gh2tg4	610	40	an	an	DT
cord-310847-63gh2tg4	610	41	extracellular	extracellular	JJ
cord-310847-63gh2tg4	610	42	Ca	Ca	NNP
cord-310847-63gh2tg4	610	43	2	2	CD
cord-310847-63gh2tg4	610	44	+	+	SYM
cord-310847-63gh2tg4	610	45	-binding	-binding	NN
cord-310847-63gh2tg4	610	46	(	(	-LRB-
cord-310847-63gh2tg4	610	47	EC	EC	NNP
cord-310847-63gh2tg4	610	48	)	)	-RRB-
cord-310847-63gh2tg4	610	49	module	module	NN
cord-310847-63gh2tg4	610	50	that	that	WDT
cord-310847-63gh2tg4	610	51	contains	contain	VBZ
cord-310847-63gh2tg4	610	52	two	two	CD
cord-310847-63gh2tg4	610	53	EF	EF	NNP
cord-310847-63gh2tg4	610	54	-	-	HYPH
cord-310847-63gh2tg4	610	55	hands	hand	NNS
cord-310847-63gh2tg4	610	56	and	and	CC
cord-310847-63gh2tg4	610	57	two	two	CD
cord-310847-63gh2tg4	610	58	collagen	collagen	NN
cord-310847-63gh2tg4	610	59	-	-	HYPH
cord-310847-63gh2tg4	610	60	binding	bind	VBG
cord-310847-63gh2tg4	610	61	epitopes	epitope	NNS
cord-310847-63gh2tg4	610	62	(	(	-LRB-
cord-310847-63gh2tg4	610	63	domain	domain	NN
cord-310847-63gh2tg4	610	64	III	iii	CD
cord-310847-63gh2tg4	610	65	)	)	-RRB-
cord-310847-63gh2tg4	610	66	.	.	.
cord-310847-63gh2tg4	611	1	Since	since	IN
cord-310847-63gh2tg4	611	2	domain	domain	NN
cord-310847-63gh2tg4	611	3	I	-PRON-	PRP
cord-310847-63gh2tg4	611	4	was	be	VBD
cord-310847-63gh2tg4	611	5	not	not	RB
cord-310847-63gh2tg4	611	6	found	find	VBN
cord-310847-63gh2tg4	611	7	in	in	IN
cord-310847-63gh2tg4	611	8	SPARC	SPARC	NNP
cord-310847-63gh2tg4	611	9	isolated	isolate	VBN
cord-310847-63gh2tg4	611	10	from	from	IN
cord-310847-63gh2tg4	611	11	the	the	DT
cord-310847-63gh2tg4	611	12	starlet	starlet	NN
cord-310847-63gh2tg4	611	13	anemone	anemone	NN
cord-310847-63gh2tg4	611	14	Nematostella	Nematostella	NNP
cord-310847-63gh2tg4	611	15	vectensis	vectensis	NN
cord-310847-63gh2tg4	611	16	,	,	,
cord-310847-63gh2tg4	611	17	it	-PRON-	PRP
cord-310847-63gh2tg4	611	18	has	have	VBZ
cord-310847-63gh2tg4	611	19	been	be	VBN
cord-310847-63gh2tg4	611	20	proposed	propose	VBN
cord-310847-63gh2tg4	611	21	that	that	IN
cord-310847-63gh2tg4	611	22	SPARC	SPARC	NNP
cord-310847-63gh2tg4	611	23	first	first	RB
cord-310847-63gh2tg4	611	24	evolved	evolve	VBD
cord-310847-63gh2tg4	611	25	as	as	IN
cord-310847-63gh2tg4	611	26	a	a	DT
cord-310847-63gh2tg4	611	27	collagen	collagen	NN
cord-310847-63gh2tg4	611	28	-	-	HYPH
cord-310847-63gh2tg4	611	29	binding	bind	VBG
cord-310847-63gh2tg4	611	30	matricellular	matricellular	JJ
cord-310847-63gh2tg4	611	31	glycoprotein	glycoprotein	NN
cord-310847-63gh2tg4	611	32	.	.	.
cord-310847-63gh2tg4	612	1	201	201	CD
cord-310847-63gh2tg4	612	2	Human	Human	NNP
cord-310847-63gh2tg4	612	3	SPARC	SPARC	NNP
cord-310847-63gh2tg4	612	4	is	be	VBZ
cord-310847-63gh2tg4	612	5	a	a	DT
cord-310847-63gh2tg4	612	6	303	303	CD
cord-310847-63gh2tg4	612	7	residueslong	residueslong	NN
cord-310847-63gh2tg4	612	8	protein	protein	NN
cord-310847-63gh2tg4	612	9	that	that	WDT
cord-310847-63gh2tg4	612	10	contains	contain	VBZ
cord-310847-63gh2tg4	612	11	34	34	CD
cord-310847-63gh2tg4	612	12	glutamic	glutamic	NN
cord-310847-63gh2tg4	612	13	acids	acid	NNS
cord-310847-63gh2tg4	612	14	,	,	,
cord-310847-63gh2tg4	612	15	15	15	CD
cord-310847-63gh2tg4	612	16	of	of	IN
cord-310847-63gh2tg4	612	17	which	which	WDT
cord-310847-63gh2tg4	612	18	are	be	VBP
cord-310847-63gh2tg4	612	19	located	locate	VBN
cord-310847-63gh2tg4	612	20	within	within	IN
cord-310847-63gh2tg4	612	21	the	the	DT
cord-310847-63gh2tg4	612	22	N	n	CD
cord-310847-63gh2tg4	612	23	-	-	HYPH
cord-310847-63gh2tg4	612	24	terminal	terminal	NN
cord-310847-63gh2tg4	612	25	calcium	calcium	NN
cord-310847-63gh2tg4	612	26	binding	bind	VBG
cord-310847-63gh2tg4	612	27	region	region	NN
cord-310847-63gh2tg4	612	28	(	(	-LRB-
cord-310847-63gh2tg4	612	29	residues	residue	NNS
cord-310847-63gh2tg4	612	30	22	22	CD
cord-310847-63gh2tg4	612	31	-	-	SYM
cord-310847-63gh2tg4	612	32	69	69	CD
cord-310847-63gh2tg4	612	33	)	)	-RRB-
cord-310847-63gh2tg4	612	34	.	.	.
cord-310847-63gh2tg4	613	1	Although	although	IN
cord-310847-63gh2tg4	613	2	Xenopus	Xenopus	NNP
cord-310847-63gh2tg4	613	3	laevis	laevi	NNS
cord-310847-63gh2tg4	613	4	SPARC	SPARC	NNP
cord-310847-63gh2tg4	613	5	has	have	VBZ
cord-310847-63gh2tg4	613	6	a	a	DT
cord-310847-63gh2tg4	613	7	molecular	molecular	JJ
cord-310847-63gh2tg4	613	8	mass	mass	NN
cord-310847-63gh2tg4	613	9	of	of	IN
cord-310847-63gh2tg4	613	10	32.6	32.6	CD
cord-310847-63gh2tg4	613	11	kDa	kDa	NNPS
cord-310847-63gh2tg4	613	12	,	,	,
cord-310847-63gh2tg4	613	13	based	base	VBN
cord-310847-63gh2tg4	613	14	on	on	IN
cord-310847-63gh2tg4	613	15	SDS	SDS	NNP
cord-310847-63gh2tg4	613	16	-	-	HYPH
cord-310847-63gh2tg4	613	17	PAGE	PAGE	NNP
cord-310847-63gh2tg4	613	18	analysis	analysis	NN
cord-310847-63gh2tg4	613	19	this	this	DT
cord-310847-63gh2tg4	613	20	protein	protein	NN
cord-310847-63gh2tg4	613	21	has	have	VBZ
cord-310847-63gh2tg4	613	22	a	a	DT
cord-310847-63gh2tg4	613	23	molecular	molecular	JJ
cord-310847-63gh2tg4	613	24	mass	mass	NN
cord-310847-63gh2tg4	613	25	of	of	IN
cord-310847-63gh2tg4	613	26	43	43	CD
cord-310847-63gh2tg4	613	27	kDa	kDa	NNS
cord-310847-63gh2tg4	613	28	.	.	.
cord-310847-63gh2tg4	613	29	200	200	CD
cord-310847-63gh2tg4	613	30	NBP-45	NBP-45	NNP
cord-310847-63gh2tg4	613	31	.	.	.
cord-310847-63gh2tg4	614	1	In	in	IN
cord-310847-63gh2tg4	614	2	nuclei	nucleus	NNS
cord-310847-63gh2tg4	614	3	of	of	IN
cord-310847-63gh2tg4	614	4	mice	mouse	NNS
cord-310847-63gh2tg4	614	5	cells	cell	NNS
cord-310847-63gh2tg4	614	6	,	,	,
cord-310847-63gh2tg4	614	7	there	there	EX
cord-310847-63gh2tg4	614	8	is	be	VBZ
cord-310847-63gh2tg4	614	9	a	a	DT
cord-310847-63gh2tg4	614	10	nuclear	nuclear	JJ
cord-310847-63gh2tg4	614	11	protein	protein	NN
cord-310847-63gh2tg4	614	12	NBP-45	NBP-45	NNP
cord-310847-63gh2tg4	614	13	related	relate	VBD
cord-310847-63gh2tg4	614	14	to	to	IN
cord-310847-63gh2tg4	614	15	the	the	DT
cord-310847-63gh2tg4	614	16	nuclear	nuclear	JJ
cord-310847-63gh2tg4	614	17	proteins	protein	NNS
cord-310847-63gh2tg4	614	18	HMG-14/-17	hmg-14/-17	UH
cord-310847-63gh2tg4	614	19	.	.	.
cord-310847-63gh2tg4	615	1	NBP-45	NBP-45	NNP
cord-310847-63gh2tg4	615	2	can	can	MD
cord-310847-63gh2tg4	615	3	function	function	VB
cord-310847-63gh2tg4	615	4	as	as	IN
cord-310847-63gh2tg4	615	5	a	a	DT
cord-310847-63gh2tg4	615	6	transcriptional	transcriptional	JJ
cord-310847-63gh2tg4	615	7	activator	activator	NN
cord-310847-63gh2tg4	615	8	,	,	,
cord-310847-63gh2tg4	615	9	binds	bind	VBZ
cord-310847-63gh2tg4	615	10	specifically	specifically	RB
cord-310847-63gh2tg4	615	11	to	to	TO
cord-310847-63gh2tg4	615	12	nucleosome	nucleosome	VB
cord-310847-63gh2tg4	615	13	core	core	NN
cord-310847-63gh2tg4	615	14	particles	particle	NNS
cord-310847-63gh2tg4	615	15	,	,	,
cord-310847-63gh2tg4	615	16	202	202	CD
cord-310847-63gh2tg4	615	17	preferentially	preferentially	RB
cord-310847-63gh2tg4	615	18	binds	bind	VBZ
cord-310847-63gh2tg4	615	19	to	to	IN
cord-310847-63gh2tg4	615	20	euchromatin	euchromatin	VB
cord-310847-63gh2tg4	615	21	and	and	CC
cord-310847-63gh2tg4	615	22	modulates	modulate	VBZ
cord-310847-63gh2tg4	615	23	cellular	cellular	JJ
cord-310847-63gh2tg4	615	24	transcription	transcription	NN
cord-310847-63gh2tg4	615	25	by	by	IN
cord-310847-63gh2tg4	615	26	counteracting	counteract	VBG
cord-310847-63gh2tg4	615	27	linker	linker	NN
cord-310847-63gh2tg4	615	28	histone	histone	NN
cord-310847-63gh2tg4	615	29	-	-	HYPH
cord-310847-63gh2tg4	615	30	mediated	mediate	VBN
cord-310847-63gh2tg4	615	31	chromatin	chromatin	NN
cord-310847-63gh2tg4	615	32	compaction	compaction	NN
cord-310847-63gh2tg4	615	33	.	.	.
cord-310847-63gh2tg4	616	1	203	203	CD
cord-310847-63gh2tg4	616	2	NBP-45	NBP-45	NNP
cord-310847-63gh2tg4	616	3	is	be	VBZ
cord-310847-63gh2tg4	616	4	composed	compose	VBN
cord-310847-63gh2tg4	616	5	of	of	IN
cord-310847-63gh2tg4	616	6	406	406	CD
cord-310847-63gh2tg4	616	7	amino	amino	JJ
cord-310847-63gh2tg4	616	8	acids	acid	NNS
cord-310847-63gh2tg4	616	9	and	and	CC
cord-310847-63gh2tg4	616	10	has	have	VBZ
cord-310847-63gh2tg4	616	11	several	several	JJ
cord-310847-63gh2tg4	616	12	functional	functional	JJ
cord-310847-63gh2tg4	616	13	regions	region	NNS
cord-310847-63gh2tg4	616	14	and	and	CC
cord-310847-63gh2tg4	616	15	domains	domain	NNS
cord-310847-63gh2tg4	616	16	:	:	:
cord-310847-63gh2tg4	616	17	the	the	DT
cord-310847-63gh2tg4	616	18	N	n	CD
cord-310847-63gh2tg4	616	19	-	-	HYPH
cord-310847-63gh2tg4	616	20	terminal	terminal	NN
cord-310847-63gh2tg4	616	21	region	region	NN
cord-310847-63gh2tg4	616	22	(	(	-LRB-
cord-310847-63gh2tg4	616	23	residues	residue	NNS
cord-310847-63gh2tg4	616	24	1	1	CD
cord-310847-63gh2tg4	616	25	-	-	SYM
cord-310847-63gh2tg4	616	26	85	85	CD
cord-310847-63gh2tg4	616	27	)	)	-RRB-
cord-310847-63gh2tg4	616	28	contains	contain	VBZ
cord-310847-63gh2tg4	616	29	three	three	CD
cord-310847-63gh2tg4	616	30	segments	segment	NNS
cord-310847-63gh2tg4	616	31	that	that	WDT
cord-310847-63gh2tg4	616	32	are	be	VBP
cord-310847-63gh2tg4	616	33	highly	highly	RB
cord-310847-63gh2tg4	616	34	homologous	homologous	JJ
cord-310847-63gh2tg4	616	35	to	to	IN
cord-310847-63gh2tg4	616	36	functionally	functionally	RB
cord-310847-63gh2tg4	616	37	important	important	JJ
cord-310847-63gh2tg4	616	38	domains	domain	NNS
cord-310847-63gh2tg4	616	39	in	in	IN
cord-310847-63gh2tg4	616	40	the	the	DT
cord-310847-63gh2tg4	616	41	HMG-14/-17	HMG-14/-17	NNP
cord-310847-63gh2tg4	616	42	protein	protein	NN
cord-310847-63gh2tg4	616	43	family	family	NN
cord-310847-63gh2tg4	616	44	,	,	,
cord-310847-63gh2tg4	616	45	namely	namely	RB
cord-310847-63gh2tg4	616	46	a	a	DT
cord-310847-63gh2tg4	616	47	nuclear	nuclear	JJ
cord-310847-63gh2tg4	616	48	localization	localization	NN
cord-310847-63gh2tg4	616	49	signal	signal	NN
cord-310847-63gh2tg4	616	50	,	,	,
cord-310847-63gh2tg4	616	51	a	a	DT
cord-310847-63gh2tg4	616	52	nucleosome	nucleosome	NN
cord-310847-63gh2tg4	616	53	binding	bind	VBG
cord-310847-63gh2tg4	616	54	domain	domain	NN
cord-310847-63gh2tg4	616	55	and	and	CC
cord-310847-63gh2tg4	616	56	a	a	DT
cord-310847-63gh2tg4	616	57	chromatin	chromatin	NN
cord-310847-63gh2tg4	616	58	unfolding	unfold	VBG
cord-310847-63gh2tg4	616	59	domain	domain	NN
cord-310847-63gh2tg4	616	60	,	,	,
cord-310847-63gh2tg4	616	61	whereas	whereas	IN
cord-310847-63gh2tg4	616	62	the	the	DT
cord-310847-63gh2tg4	616	63	C	C	NNP
cord-310847-63gh2tg4	616	64	-	-	HYPH
cord-310847-63gh2tg4	616	65	terminal	terminal	NN
cord-310847-63gh2tg4	616	66	region	region	NN
cord-310847-63gh2tg4	616	67	(	(	-LRB-
cord-310847-63gh2tg4	616	68	residues	residue	NNS
cord-310847-63gh2tg4	616	69	86	86	CD
cord-310847-63gh2tg4	616	70	-	-	SYM
cord-310847-63gh2tg4	616	71	406	406	CD
cord-310847-63gh2tg4	616	72	)	)	-RRB-
cord-310847-63gh2tg4	616	73	has	have	VBZ
cord-310847-63gh2tg4	616	74	43.7	43.7	CD
cord-310847-63gh2tg4	616	75	%	%	NN
cord-310847-63gh2tg4	616	76	of	of	IN
cord-310847-63gh2tg4	616	77	negatively	negatively	RB
cord-310847-63gh2tg4	616	78	charged	charge	VBN
cord-310847-63gh2tg4	616	79	residues	residue	NNS
cord-310847-63gh2tg4	616	80	.	.	.
cord-310847-63gh2tg4	617	1	202	202	CD
cord-310847-63gh2tg4	618	1	In	in	IN
cord-310847-63gh2tg4	618	2	fact	fact	NN
cord-310847-63gh2tg4	618	3	,	,	,
cord-310847-63gh2tg4	618	4	of	of	IN
cord-310847-63gh2tg4	618	5	the	the	DT
cord-310847-63gh2tg4	618	6	110	110	CD
cord-310847-63gh2tg4	618	7	glutamic	glutamic	NN
cord-310847-63gh2tg4	618	8	acids	acid	NNS
cord-310847-63gh2tg4	618	9	and	and	CC
cord-310847-63gh2tg4	618	10	44	44	CD
cord-310847-63gh2tg4	618	11	aspartic	aspartic	JJ
cord-310847-63gh2tg4	618	12	acids	acid	NNS
cord-310847-63gh2tg4	618	13	found	find	VBN
cord-310847-63gh2tg4	618	14	in	in	IN
cord-310847-63gh2tg4	618	15	NBP-45	NBP-45	NNP
cord-310847-63gh2tg4	618	16	,	,	,
cord-310847-63gh2tg4	618	17	100	100	CD
cord-310847-63gh2tg4	618	18	glutamic	glutamic	NN
cord-310847-63gh2tg4	618	19	and	and	CC
cord-310847-63gh2tg4	618	20	40	40	CD
cord-310847-63gh2tg4	618	21	aspartic	aspartic	JJ
cord-310847-63gh2tg4	618	22	acids	acid	NNS
cord-310847-63gh2tg4	618	23	are	be	VBP
cord-310847-63gh2tg4	618	24	located	locate	VBN
cord-310847-63gh2tg4	618	25	in	in	IN
cord-310847-63gh2tg4	618	26	this	this	DT
cord-310847-63gh2tg4	618	27	highly	highly	RB
cord-310847-63gh2tg4	618	28	acidic	acidic	JJ
cord-310847-63gh2tg4	618	29	region	region	NN
cord-310847-63gh2tg4	618	30	.	.	.
cord-310847-63gh2tg4	619	1	GARPs	garp	NNS
cord-310847-63gh2tg4	619	2	in	in	IN
cord-310847-63gh2tg4	619	3	rod	rod	NN
cord-310847-63gh2tg4	619	4	photoreceptors	photoreceptor	NNS
cord-310847-63gh2tg4	619	5	.	.	.
cord-310847-63gh2tg4	620	1	Glutamic	glutamic	NN
cord-310847-63gh2tg4	620	2	acid	acid	NN
cord-310847-63gh2tg4	620	3	-	-	HYPH
cord-310847-63gh2tg4	620	4	rich	rich	JJ
cord-310847-63gh2tg4	620	5	proteins	protein	NNS
cord-310847-63gh2tg4	620	6	(	(	-LRB-
cord-310847-63gh2tg4	620	7	GARPs	GARPs	NNP
cord-310847-63gh2tg4	620	8	)	)	-RRB-
cord-310847-63gh2tg4	620	9	are	be	VBP
cord-310847-63gh2tg4	620	10	common	common	JJ
cord-310847-63gh2tg4	620	11	in	in	IN
cord-310847-63gh2tg4	620	12	different	different	JJ
cord-310847-63gh2tg4	620	13	organisms	organism	NNS
cord-310847-63gh2tg4	620	14	and	and	CC
cord-310847-63gh2tg4	620	15	have	have	VBP
cord-310847-63gh2tg4	620	16	numerous	numerous	JJ
cord-310847-63gh2tg4	620	17	biological	biological	JJ
cord-310847-63gh2tg4	620	18	functions	function	NNS
cord-310847-63gh2tg4	620	19	.	.	.
cord-310847-63gh2tg4	621	1	For	for	IN
cord-310847-63gh2tg4	621	2	example	example	NN
cord-310847-63gh2tg4	621	3	,	,	,
cord-310847-63gh2tg4	621	4	rod	rod	NN
cord-310847-63gh2tg4	621	5	photoreceptors	photoreceptor	NNS
cord-310847-63gh2tg4	621	6	contain	contain	VBP
cord-310847-63gh2tg4	621	7	three	three	CD
cord-310847-63gh2tg4	621	8	different	different	JJ
cord-310847-63gh2tg4	621	9	glutamic	glutamic	NN
cord-310847-63gh2tg4	621	10	acid	acid	NN
cord-310847-63gh2tg4	621	11	-	-	HYPH
cord-310847-63gh2tg4	621	12	rich	rich	JJ
cord-310847-63gh2tg4	621	13	proteins	protein	NNS
cord-310847-63gh2tg4	621	14	(	(	-LRB-
cord-310847-63gh2tg4	621	15	GARPs	GARPs	NNP
cord-310847-63gh2tg4	621	16	)	)	-RRB-
cord-310847-63gh2tg4	621	17	,	,	,
cord-310847-63gh2tg4	621	18	two	two	CD
cord-310847-63gh2tg4	621	19	soluble	soluble	JJ
cord-310847-63gh2tg4	621	20	forms	form	NNS
cord-310847-63gh2tg4	621	21	,	,	,
cord-310847-63gh2tg4	621	22	GARP1	GARP1	NNP
cord-310847-63gh2tg4	621	23	and	and	CC
cord-310847-63gh2tg4	621	24	GARP2	GARP2	NNP
cord-310847-63gh2tg4	621	25	,	,	,
cord-310847-63gh2tg4	621	26	and	and	CC
cord-310847-63gh2tg4	621	27	the	the	DT
cord-310847-63gh2tg4	621	28	N	n	CD
cord-310847-63gh2tg4	621	29	-	-	HYPH
cord-310847-63gh2tg4	621	30	terminal	terminal	JJ
cord-310847-63gh2tg4	621	31	cytoplasmic	cytoplasmic	JJ
cord-310847-63gh2tg4	621	32	domain	domain	NN
cord-310847-63gh2tg4	621	33	(	(	-LRB-
cord-310847-63gh2tg4	621	34	GARP	GARP	NNP
cord-310847-63gh2tg4	621	35	part	part	NN
cord-310847-63gh2tg4	621	36	)	)	-RRB-
cord-310847-63gh2tg4	621	37	of	of	IN
cord-310847-63gh2tg4	621	38	the	the	DT
cord-310847-63gh2tg4	621	39	B1	b1	NN
cord-310847-63gh2tg4	621	40	subunit	subunit	NN
cord-310847-63gh2tg4	621	41	of	of	IN
cord-310847-63gh2tg4	621	42	the	the	DT
cord-310847-63gh2tg4	621	43	cyclic	cyclic	JJ
cord-310847-63gh2tg4	621	44	GMP	GMP	NNP
cord-310847-63gh2tg4	621	45	-	-	HYPH
cord-310847-63gh2tg4	621	46	gated	gate	VBN
cord-310847-63gh2tg4	621	47	channel	channel	NN
cord-310847-63gh2tg4	621	48	(	(	-LRB-
cord-310847-63gh2tg4	621	49	also	also	RB
cord-310847-63gh2tg4	621	50	known	know	VBN
cord-310847-63gh2tg4	621	51	as	as	IN
cord-310847-63gh2tg4	621	52	cyclic	cyclic	JJ
cord-310847-63gh2tg4	621	53	nucleotide	nucleotide	RB
cord-310847-63gh2tg4	621	54	-	-	HYPH
cord-310847-63gh2tg4	621	55	gated	gate	VBN
cord-310847-63gh2tg4	621	56	cation	cation	NN
cord-310847-63gh2tg4	621	57	channel	channel	NN
cord-310847-63gh2tg4	621	58	β-1	β-1	NNP
cord-310847-63gh2tg4	621	59	,	,	,
cord-310847-63gh2tg4	621	60	CNGB1	CNGB1	NNP
cord-310847-63gh2tg4	621	61	)	)	-RRB-
cord-310847-63gh2tg4	621	62	,	,	,
cord-310847-63gh2tg4	621	63	that	that	WDT
cord-310847-63gh2tg4	621	64	are	be	VBP
cord-310847-63gh2tg4	621	65	involved	involve	VBN
cord-310847-63gh2tg4	621	66	in	in	IN
cord-310847-63gh2tg4	621	67	the	the	DT
cord-310847-63gh2tg4	621	68	control	control	NN
cord-310847-63gh2tg4	621	69	of	of	IN
cord-310847-63gh2tg4	621	70	the	the	DT
cord-310847-63gh2tg4	621	71	Ca	Ca	NNP
cord-310847-63gh2tg4	621	72	2	2	CD
cord-310847-63gh2tg4	621	73	+	+	CC
cord-310847-63gh2tg4	621	74	propagation	propagation	NN
cord-310847-63gh2tg4	621	75	from	from	IN
cord-310847-63gh2tg4	621	76	the	the	DT
cord-310847-63gh2tg4	621	77	site	site	NN
cord-310847-63gh2tg4	621	78	of	of	IN
cord-310847-63gh2tg4	621	79	its	-PRON-	PRP$
cord-310847-63gh2tg4	621	80	entry	entry	NN
cord-310847-63gh2tg4	621	81	at	at	IN
cord-310847-63gh2tg4	621	82	the	the	DT
cord-310847-63gh2tg4	621	83	cyclic	cyclic	JJ
cord-310847-63gh2tg4	621	84	nucleotidegated	nucleotidegated	JJ
cord-310847-63gh2tg4	621	85	channel	channel	NN
cord-310847-63gh2tg4	621	86	to	to	IN
cord-310847-63gh2tg4	621	87	the	the	DT
cord-310847-63gh2tg4	621	88	cytosol	cytosol	NN
cord-310847-63gh2tg4	621	89	of	of	IN
cord-310847-63gh2tg4	621	90	the	the	DT
cord-310847-63gh2tg4	621	91	outer	outer	JJ
cord-310847-63gh2tg4	621	92	segment	segment	NN
cord-310847-63gh2tg4	621	93	.	.	.
cord-310847-63gh2tg4	622	1	204	204	CD
cord-310847-63gh2tg4	623	1	The	the	DT
cord-310847-63gh2tg4	623	2	cyclic	cyclic	JJ
cord-310847-63gh2tg4	623	3	acid	acid	NN
cord-310847-63gh2tg4	623	4	-	-	HYPH
cord-310847-63gh2tg4	623	5	rich	rich	JJ
cord-310847-63gh2tg4	623	6	domains	domain	NNS
cord-310847-63gh2tg4	623	7	or	or	CC
cord-310847-63gh2tg4	623	8	regions	region	NNS
cord-310847-63gh2tg4	623	9	.	.	.
cord-310847-63gh2tg4	624	1	For	for	IN
cord-310847-63gh2tg4	624	2	example	example	NN
cord-310847-63gh2tg4	624	3	,	,	,
cord-310847-63gh2tg4	624	4	the	the	DT
cord-310847-63gh2tg4	624	5	non	non	JJ
cord-310847-63gh2tg4	624	6	-	-	JJ
cord-310847-63gh2tg4	624	7	epithelial	epithelial	JJ
cord-310847-63gh2tg4	624	8	intermediate	intermediate	JJ
cord-310847-63gh2tg4	624	9	filament	filament	NN
cord-310847-63gh2tg4	624	10	(	(	-LRB-
cord-310847-63gh2tg4	624	11	IF	if	NN
cord-310847-63gh2tg4	624	12	)	)	-RRB-
cord-310847-63gh2tg4	624	13	subunit	subunit	NN
cord-310847-63gh2tg4	624	14	protein	protein	NN
cord-310847-63gh2tg4	624	15	(	(	-LRB-
cord-310847-63gh2tg4	624	16	e.g.	e.g.	RB
cord-310847-63gh2tg4	624	17	,	,	,
cord-310847-63gh2tg4	624	18	human	human	JJ
cord-310847-63gh2tg4	624	19	vimentin	vimentin	NNS
cord-310847-63gh2tg4	624	20	,	,	,
cord-310847-63gh2tg4	624	21	which	which	WDT
cord-310847-63gh2tg4	624	22	is	be	VBZ
cord-310847-63gh2tg4	624	23	attached	attach	VBN
cord-310847-63gh2tg4	624	24	to	to	IN
cord-310847-63gh2tg4	624	25	the	the	DT
cord-310847-63gh2tg4	624	26	nucleus	nucleus	NN
cord-310847-63gh2tg4	624	27	,	,	,
cord-310847-63gh2tg4	624	28	endoplasmic	endoplasmic	NN
cord-310847-63gh2tg4	624	29	reticulum	reticulum	NN
cord-310847-63gh2tg4	624	30	and	and	CC
cord-310847-63gh2tg4	624	31	mitochondria	mitochondrion	NNS
cord-310847-63gh2tg4	624	32	,	,	,
cord-310847-63gh2tg4	624	33	either	either	CC
cord-310847-63gh2tg4	624	34	laterally	laterally	RB
cord-310847-63gh2tg4	624	35	or	or	CC
cord-310847-63gh2tg4	624	36	terminally	terminally	RB
cord-310847-63gh2tg4	624	37	and	and	CC
cord-310847-63gh2tg4	624	38	that	that	DT
cord-310847-63gh2tg4	624	39	contains	contain	VBZ
cord-310847-63gh2tg4	624	40	11.8	11.8	CD
cord-310847-63gh2tg4	624	41	%	%	NN
cord-310847-63gh2tg4	624	42	glutamic	glutamic	NN
cord-310847-63gh2tg4	624	43	acids	acid	NNS
cord-310847-63gh2tg4	624	44	)	)	-RRB-
cord-310847-63gh2tg4	624	45	can	can	MD
cord-310847-63gh2tg4	624	46	specifically	specifically	RB
cord-310847-63gh2tg4	624	47	bind	bind	VB
cord-310847-63gh2tg4	624	48	core	core	NN
cord-310847-63gh2tg4	624	49	histones	histone	NNS
cord-310847-63gh2tg4	624	50	with	with	IN
cord-310847-63gh2tg4	624	51	a	a	DT
cord-310847-63gh2tg4	624	52	stoichiometry	stoichiometry	NN
cord-310847-63gh2tg4	624	53	of	of	IN
cord-310847-63gh2tg4	624	54	8	8	CD
cord-310847-63gh2tg4	624	55	core	core	NN
cord-310847-63gh2tg4	624	56	histones	histone	NNS
cord-310847-63gh2tg4	624	57	per	per	IN
cord-310847-63gh2tg4	624	58	a	a	DT
cord-310847-63gh2tg4	624	59	nonneuronal	nonneuronal	NN
cord-310847-63gh2tg4	624	60	IF	if	IN
cord-310847-63gh2tg4	624	61	protein	protein	NN
cord-310847-63gh2tg4	624	62	dimer	dimer	NN
cord-310847-63gh2tg4	624	63	.	.	.
cord-310847-63gh2tg4	625	1	194	194	CD
cord-310847-63gh2tg4	625	2	Glutamic	glutamic	NN
cord-310847-63gh2tg4	625	3	acids	acid	NNS
cord-310847-63gh2tg4	625	4	clearly	clearly	RB
cord-310847-63gh2tg4	625	5	play	play	VBP
cord-310847-63gh2tg4	625	6	a	a	DT
cord-310847-63gh2tg4	625	7	crucial	crucial	JJ
cord-310847-63gh2tg4	625	8	role	role	NN
cord-310847-63gh2tg4	625	9	in	in	IN
cord-310847-63gh2tg4	625	10	this	this	DT
cord-310847-63gh2tg4	625	11	interaction	interaction	NN
cord-310847-63gh2tg4	625	12	since	since	IN
cord-310847-63gh2tg4	625	13	the	the	DT
cord-310847-63gh2tg4	625	14	68	68	CD
cord-310847-63gh2tg4	625	15	kD	kD	NNP
cord-310847-63gh2tg4	625	16	neurofilament	neurofilament	NNP
cord-310847-63gh2tg4	625	17	protein	protein	NN
cord-310847-63gh2tg4	625	18	,	,	,
cord-310847-63gh2tg4	625	19	which	which	WDT
cord-310847-63gh2tg4	625	20	was	be	VBD
cord-310847-63gh2tg4	625	21	already	already	RB
cord-310847-63gh2tg4	625	22	discussed	discuss	VBN
cord-310847-63gh2tg4	625	23	in	in	IN
cord-310847-63gh2tg4	625	24	the	the	DT
cord-310847-63gh2tg4	625	25	EBD	EBD	NNP
cord-310847-63gh2tg4	625	26	section	section	NN
cord-310847-63gh2tg4	625	27	and	and	CC
cord-310847-63gh2tg4	625	28	contains	contain	VBZ
cord-310847-63gh2tg4	625	29	a	a	DT
cord-310847-63gh2tg4	625	30	glutamic	glutamic	NN
cord-310847-63gh2tg4	625	31	acid	acid	NN
cord-310847-63gh2tg4	625	32	-	-	HYPH
cord-310847-63gh2tg4	625	33	rich	rich	JJ
cord-310847-63gh2tg4	625	34	C	c	NN
cord-310847-63gh2tg4	625	35	-	-	HYPH
cord-310847-63gh2tg4	625	36	terminal	terminal	NN
cord-310847-63gh2tg4	625	37	extension	extension	NN
cord-310847-63gh2tg4	625	38	,	,	,
cord-310847-63gh2tg4	625	39	can	can	MD
cord-310847-63gh2tg4	625	40	bind	bind	VB
cord-310847-63gh2tg4	625	41	more	more	JJR
cord-310847-63gh2tg4	625	42	core	core	NN
cord-310847-63gh2tg4	625	43	histones	histone	NNS
cord-310847-63gh2tg4	625	44	per	per	IN
cord-310847-63gh2tg4	625	45	dimer	dimer	NN
cord-310847-63gh2tg4	625	46	(	(	-LRB-
cord-310847-63gh2tg4	625	47	24	24	CD
cord-310847-63gh2tg4	625	48	molecules	molecule	NNS
cord-310847-63gh2tg4	625	49	of	of	IN
cord-310847-63gh2tg4	625	50	core	core	NN
cord-310847-63gh2tg4	625	51	histones	histone	NNS
cord-310847-63gh2tg4	625	52	)	)	-RRB-
cord-310847-63gh2tg4	625	53	than	than	IN
cord-310847-63gh2tg4	625	54	the	the	DT
cord-310847-63gh2tg4	625	55	dimer	dimer	NN
cord-310847-63gh2tg4	625	56	of	of	IN
cord-310847-63gh2tg4	625	57	the	the	DT
cord-310847-63gh2tg4	625	58	non	non	JJ
cord-310847-63gh2tg4	625	59	-	-	JJ
cord-310847-63gh2tg4	625	60	neuronal	neuronal	JJ
cord-310847-63gh2tg4	625	61	IF	if	IN
cord-310847-63gh2tg4	625	62	proteins	protein	NNS
cord-310847-63gh2tg4	625	63	.	.	.
cord-310847-63gh2tg4	626	1	194	194	CD
cord-310847-63gh2tg4	627	1	In	in	IN
cord-310847-63gh2tg4	627	2	the	the	DT
cord-310847-63gh2tg4	627	3	nuclei	nucleus	NNS
cord-310847-63gh2tg4	627	4	of	of	IN
cord-310847-63gh2tg4	627	5	Physarum	Physarum	NNP
cord-310847-63gh2tg4	627	6	polycephalum	polycephalum	NN
cord-310847-63gh2tg4	627	7	,	,	,
cord-310847-63gh2tg4	627	8	there	there	EX
cord-310847-63gh2tg4	627	9	is	be	VBZ
cord-310847-63gh2tg4	627	10	an	an	DT
cord-310847-63gh2tg4	627	11	alanine	alanine	NN
cord-310847-63gh2tg4	627	12	,	,	,
cord-310847-63gh2tg4	627	13	lysine	lysine	NN
cord-310847-63gh2tg4	627	14	and	and	CC
cord-310847-63gh2tg4	627	15	glutamic	glutamic	NN
cord-310847-63gh2tg4	627	16	acid	acid	NN
cord-310847-63gh2tg4	627	17	-	-	HYPH
cord-310847-63gh2tg4	627	18	rich	rich	JJ
cord-310847-63gh2tg4	627	19	nuclear	nuclear	JJ
cord-310847-63gh2tg4	627	20	protein	protein	NN
cord-310847-63gh2tg4	627	21	(	(	-LRB-
cord-310847-63gh2tg4	627	22	P2	P2	NNP
cord-310847-63gh2tg4	627	23	)	)	-RRB-
cord-310847-63gh2tg4	627	24	with	with	IN
cord-310847-63gh2tg4	627	25	a	a	DT
cord-310847-63gh2tg4	627	26	molecular	molecular	JJ
cord-310847-63gh2tg4	627	27	mass	mass	NN
cord-310847-63gh2tg4	627	28	of	of	IN
cord-310847-63gh2tg4	627	29	~19.5	~19.5	NNP
cord-310847-63gh2tg4	627	30	kDa	kDa	NNP
cord-310847-63gh2tg4	627	31	that	that	WDT
cord-310847-63gh2tg4	627	32	can	can	MD
cord-310847-63gh2tg4	627	33	specifically	specifically	RB
cord-310847-63gh2tg4	627	34	interact	interact	VB
cord-310847-63gh2tg4	627	35	with	with	IN
cord-310847-63gh2tg4	627	36	histones	histone	NNS
cord-310847-63gh2tg4	627	37	and	and	CC
cord-310847-63gh2tg4	627	38	therefore	therefore	RB
cord-310847-63gh2tg4	627	39	is	be	VBZ
cord-310847-63gh2tg4	627	40	co	co	JJ
cord-310847-63gh2tg4	627	41	-	-	VBN
cord-310847-63gh2tg4	627	42	extracted	extract	VBN
cord-310847-63gh2tg4	627	43	with	with	IN
cord-310847-63gh2tg4	627	44	histones	histone	NNS
cord-310847-63gh2tg4	627	45	.	.	.
cord-310847-63gh2tg4	628	1	195	195	CD
cord-310847-63gh2tg4	629	1	Based	base	VBN
cord-310847-63gh2tg4	629	2	on	on	IN
cord-310847-63gh2tg4	629	3	amino	amino	NN
cord-310847-63gh2tg4	629	4	acid	acid	NN
cord-310847-63gh2tg4	629	5	sequence	sequence	NN
cord-310847-63gh2tg4	629	6	analysis	analysis	NN
cord-310847-63gh2tg4	629	7	,	,	,
cord-310847-63gh2tg4	629	8	it	-PRON-	PRP
cord-310847-63gh2tg4	629	9	has	have	VBZ
cord-310847-63gh2tg4	629	10	been	be	VBN
cord-310847-63gh2tg4	629	11	concluded	conclude	VBN
cord-310847-63gh2tg4	629	12	that	that	IN
cord-310847-63gh2tg4	629	13	P2	P2	NNP
cord-310847-63gh2tg4	629	14	is	be	VBZ
cord-310847-63gh2tg4	629	15	a	a	DT
cord-310847-63gh2tg4	629	16	HMG	HMG	NNP
cord-310847-63gh2tg4	629	17	-	-	HYPH
cord-310847-63gh2tg4	629	18	like	like	JJ
cord-310847-63gh2tg4	629	19	protein	protein	NN
cord-310847-63gh2tg4	629	20	,	,	,
cord-310847-63gh2tg4	629	21	which	which	WDT
cord-310847-63gh2tg4	629	22	,	,	,
cord-310847-63gh2tg4	629	23	according	accord	VBG
cord-310847-63gh2tg4	629	24	to	to	IN
cord-310847-63gh2tg4	629	25	CD	cd	NN
cord-310847-63gh2tg4	629	26	measurements	measurement	NNS
cord-310847-63gh2tg4	629	27	,	,	,
cord-310847-63gh2tg4	629	28	contains	contain	VBZ
cord-310847-63gh2tg4	629	29	only	only	RB
cord-310847-63gh2tg4	629	30	5	5	CD
cord-310847-63gh2tg4	629	31	%	%	NN
cord-310847-63gh2tg4	629	32	secondary	secondary	JJ
cord-310847-63gh2tg4	629	33	structure	structure	NN
cord-310847-63gh2tg4	629	34	and	and	CC
cord-310847-63gh2tg4	629	35	is	be	VBZ
cord-310847-63gh2tg4	629	36	,	,	,
cord-310847-63gh2tg4	629	37	therefore	therefore	RB
cord-310847-63gh2tg4	629	38	,	,	,
cord-310847-63gh2tg4	629	39	essentially	essentially	RB
cord-310847-63gh2tg4	629	40	unstructured	unstructured	JJ
cord-310847-63gh2tg4	629	41	under	under	IN
cord-310847-63gh2tg4	629	42	in	in	IN
cord-310847-63gh2tg4	629	43	vivo	vivo	NN
cord-310847-63gh2tg4	629	44	conditions	condition	NNS
cord-310847-63gh2tg4	629	45	.	.	.
cord-310847-63gh2tg4	630	1	195	195	CD
cord-310847-63gh2tg4	630	2	Titin	Titin	NNP
cord-310847-63gh2tg4	630	3	.	.	.
cord-310847-63gh2tg4	631	1	The	the	DT
cord-310847-63gh2tg4	631	2	gigantic	gigantic	JJ
cord-310847-63gh2tg4	631	3	protein	protein	NN
cord-310847-63gh2tg4	631	4	titin	titin	NN
cord-310847-63gh2tg4	631	5	(	(	-LRB-
cord-310847-63gh2tg4	631	6	there	there	EX
cord-310847-63gh2tg4	631	7	are	be	VBP
cord-310847-63gh2tg4	631	8	34,350	34,350	CD
cord-310847-63gh2tg4	631	9	residues	residue	NNS
cord-310847-63gh2tg4	631	10	in	in	IN
cord-310847-63gh2tg4	631	11	the	the	DT
cord-310847-63gh2tg4	631	12	human	human	JJ
cord-310847-63gh2tg4	631	13	protein	protein	NN
cord-310847-63gh2tg4	631	14	)	)	-RRB-
cord-310847-63gh2tg4	631	15	is	be	VBZ
cord-310847-63gh2tg4	631	16	a	a	DT
cord-310847-63gh2tg4	631	17	key	key	JJ
cord-310847-63gh2tg4	631	18	component	component	NN
cord-310847-63gh2tg4	631	19	in	in	IN
cord-310847-63gh2tg4	631	20	the	the	DT
cord-310847-63gh2tg4	631	21	assembly	assembly	NN
cord-310847-63gh2tg4	631	22	and	and	CC
cord-310847-63gh2tg4	631	23	functioning	functioning	NN
cord-310847-63gh2tg4	631	24	of	of	IN
cord-310847-63gh2tg4	631	25	vertebrate	vertebrate	JJ
cord-310847-63gh2tg4	631	26	striated	striated	JJ
cord-310847-63gh2tg4	631	27	muscles	muscle	NNS
cord-310847-63gh2tg4	631	28	.	.	.
cord-310847-63gh2tg4	632	1	Among	among	IN
cord-310847-63gh2tg4	632	2	numerous	numerous	JJ
cord-310847-63gh2tg4	632	3	cellular	cellular	JJ
cord-310847-63gh2tg4	632	4	functions	function	NNS
cord-310847-63gh2tg4	632	5	of	of	IN
cord-310847-63gh2tg4	632	6	titin	titin	NN
cord-310847-63gh2tg4	632	7	(	(	-LRB-
cord-310847-63gh2tg4	632	8	also	also	RB
cord-310847-63gh2tg4	632	9	known	know	VBN
cord-310847-63gh2tg4	632	10	as	as	IN
cord-310847-63gh2tg4	632	11	connectin	connectin	NNP
cord-310847-63gh2tg4	632	12	)	)	-RRB-
cord-310847-63gh2tg4	632	13	are	be	VBP
cord-310847-63gh2tg4	632	14	contribution	contribution	NN
cord-310847-63gh2tg4	632	15	to	to	IN
cord-310847-63gh2tg4	632	16	the	the	DT
cord-310847-63gh2tg4	632	17	fine	fine	JJ
cord-310847-63gh2tg4	632	18	balance	balance	NN
cord-310847-63gh2tg4	632	19	of	of	IN
cord-310847-63gh2tg4	632	20	forces	force	NNS
cord-310847-63gh2tg4	632	21	between	between	IN
cord-310847-63gh2tg4	632	22	the	the	DT
cord-310847-63gh2tg4	632	23	two	two	CD
cord-310847-63gh2tg4	632	24	halves	half	NNS
cord-310847-63gh2tg4	632	25	of	of	IN
cord-310847-63gh2tg4	632	26	the	the	DT
cord-310847-63gh2tg4	632	27	sarcomere	sarcomere	NN
cord-310847-63gh2tg4	632	28	which	which	WDT
cord-310847-63gh2tg4	632	29	is	be	VBZ
cord-310847-63gh2tg4	632	30	crucial	crucial	JJ
cord-310847-63gh2tg4	632	31	for	for	IN
cord-310847-63gh2tg4	632	32	the	the	DT
cord-310847-63gh2tg4	632	33	elasticity	elasticity	NN
cord-310847-63gh2tg4	632	34	of	of	IN
cord-310847-63gh2tg4	632	35	muscle	muscle	NN
cord-310847-63gh2tg4	632	36	cells	cell	NNS
cord-310847-63gh2tg4	632	37	,	,	,
cord-310847-63gh2tg4	632	38	as	as	RB
cord-310847-63gh2tg4	632	39	well	well	RB
cord-310847-63gh2tg4	632	40	as	as	IN
cord-310847-63gh2tg4	632	41	participation	participation	NN
cord-310847-63gh2tg4	632	42	in	in	IN
cord-310847-63gh2tg4	632	43	chromosome	chromosome	NN
cord-310847-63gh2tg4	632	44	condensation	condensation	NN
cord-310847-63gh2tg4	632	45	and	and	CC
cord-310847-63gh2tg4	632	46	chromosome	chromosome	NN
cord-310847-63gh2tg4	632	47	segregation	segregation	NN
cord-310847-63gh2tg4	632	48	during	during	IN
cord-310847-63gh2tg4	632	49	mitosis	mitosis	NN
cord-310847-63gh2tg4	632	50	of	of	IN
cord-310847-63gh2tg4	632	51	non	non	JJ
cord-310847-63gh2tg4	632	52	-	-	JJ
cord-310847-63gh2tg4	632	53	muscle	muscle	JJ
cord-310847-63gh2tg4	632	54	cells	cell	NNS
cord-310847-63gh2tg4	632	55	.	.	.
cord-310847-63gh2tg4	633	1	The	the	DT
cord-310847-63gh2tg4	633	2	ability	ability	NN
cord-310847-63gh2tg4	633	3	of	of	IN
cord-310847-63gh2tg4	633	4	titin	titin	NN
cord-310847-63gh2tg4	633	5	to	to	TO
cord-310847-63gh2tg4	633	6	reversibly	reversibly	RB
cord-310847-63gh2tg4	633	7	extend	extend	VB
cord-310847-63gh2tg4	633	8	relies	relie	NNS
cord-310847-63gh2tg4	633	9	on	on	IN
cord-310847-63gh2tg4	633	10	a	a	DT
cord-310847-63gh2tg4	633	11	set	set	NN
cord-310847-63gh2tg4	633	12	of	of	IN
cord-310847-63gh2tg4	633	13	PEVK	PEVK	NNP
cord-310847-63gh2tg4	633	14	segments	segment	NNS
cord-310847-63gh2tg4	633	15	,	,	,
cord-310847-63gh2tg4	633	16	rich	rich	JJ
cord-310847-63gh2tg4	633	17	in	in	IN
cord-310847-63gh2tg4	633	18	proline	proline	NN
cord-310847-63gh2tg4	633	19	(	(	-LRB-
cord-310847-63gh2tg4	633	20	P	p	NN
cord-310847-63gh2tg4	633	21	)	)	-RRB-
cord-310847-63gh2tg4	633	22	,	,	,
cord-310847-63gh2tg4	633	23	glutamate	glutamate	NN
cord-310847-63gh2tg4	633	24	(	(	-LRB-
cord-310847-63gh2tg4	633	25	E	E	NNP
cord-310847-63gh2tg4	633	26	)	)	-RRB-
cord-310847-63gh2tg4	633	27	,	,	,
cord-310847-63gh2tg4	633	28	valine	valine	FW
cord-310847-63gh2tg4	633	29	(	(	-LRB-
cord-310847-63gh2tg4	633	30	V	v	NN
cord-310847-63gh2tg4	633	31	)	)	-RRB-
cord-310847-63gh2tg4	633	32	and	and	CC
cord-310847-63gh2tg4	633	33	lysine	lysine	NN
cord-310847-63gh2tg4	633	34	(	(	-LRB-
cord-310847-63gh2tg4	633	35	K	K	NNP
cord-310847-63gh2tg4	633	36	)	)	-RRB-
cord-310847-63gh2tg4	633	37	residues	residue	NNS
cord-310847-63gh2tg4	633	38	.	.	.
cord-310847-63gh2tg4	634	1	The	the	DT
cord-310847-63gh2tg4	634	2	single	single	JJ
cord-310847-63gh2tg4	634	3	molecule	molecule	NN
cord-310847-63gh2tg4	634	4	analysis	analysis	NN
cord-310847-63gh2tg4	634	5	of	of	IN
cord-310847-63gh2tg4	634	6	the	the	DT
cord-310847-63gh2tg4	634	7	recombinant	recombinant	JJ
cord-310847-63gh2tg4	634	8	titin	titin	NN
cord-310847-63gh2tg4	634	9	fragment	fragment	NN
cord-310847-63gh2tg4	634	10	,	,	,
cord-310847-63gh2tg4	634	11	containing	contain	VBG
cord-310847-63gh2tg4	634	12	approximately	approximately	RB
cord-310847-63gh2tg4	634	13	28-residue	28-residue	CD
cord-310847-63gh2tg4	634	14	PEVK	PEVK	NNP
cord-310847-63gh2tg4	634	15	repeats	repeat	VBZ
cord-310847-63gh2tg4	634	16	and	and	CC
cord-310847-63gh2tg4	634	17	glutamic	glutamic	JJ
cord-310847-63gh2tg4	634	18	acid	acid	NN
cord-310847-63gh2tg4	634	19	-	-	HYPH
cord-310847-63gh2tg4	634	20	rich	rich	JJ
cord-310847-63gh2tg4	634	21	motifs	motif	NNS
cord-310847-63gh2tg4	634	22	,	,	,
cord-310847-63gh2tg4	634	23	revealed	reveal	VBD
cord-310847-63gh2tg4	634	24	that	that	IN
cord-310847-63gh2tg4	634	25	the	the	DT
cord-310847-63gh2tg4	634	26	bending	bend	VBG
cord-310847-63gh2tg4	634	27	rigidity	rigidity	NN
cord-310847-63gh2tg4	634	28	of	of	IN
cord-310847-63gh2tg4	634	29	the	the	DT
cord-310847-63gh2tg4	634	30	PEVK	PEVK	NNP
cord-310847-63gh2tg4	634	31	fragments	fragment	NNS
cord-310847-63gh2tg4	634	32	can	can	MD
cord-310847-63gh2tg4	634	33	be	be	VB
cord-310847-63gh2tg4	634	34	reduced	reduce	VBN
cord-310847-63gh2tg4	634	35	due	due	IN
cord-310847-63gh2tg4	634	36	to	to	IN
cord-310847-63gh2tg4	634	37	calcium	calcium	NN
cord-310847-63gh2tg4	634	38	-	-	HYPH
cord-310847-63gh2tg4	634	39	induced	induce	VBN
cord-310847-63gh2tg4	634	40	conformational	conformational	JJ
cord-310847-63gh2tg4	634	41	changes	change	NNS
cord-310847-63gh2tg4	634	42	.	.	.
cord-310847-63gh2tg4	635	1	196	196	CD
cord-310847-63gh2tg4	636	1	Furthermore	furthermore	RB
cord-310847-63gh2tg4	636	2	,	,	,
cord-310847-63gh2tg4	636	3	the	the	DT
cord-310847-63gh2tg4	636	4	glutamic	glutamic	NN
cord-310847-63gh2tg4	636	5	acid	acid	NN
cord-310847-63gh2tg4	636	6	-	-	HYPH
cord-310847-63gh2tg4	636	7	rich	rich	JJ
cord-310847-63gh2tg4	636	8	motif	motif	NN
cord-310847-63gh2tg4	636	9	was	be	VBD
cord-310847-63gh2tg4	636	10	shown	show	VBN
cord-310847-63gh2tg4	636	11	to	to	TO
cord-310847-63gh2tg4	636	12	be	be	VB
cord-310847-63gh2tg4	636	13	critical	critical	JJ
cord-310847-63gh2tg4	636	14	for	for	IN
cord-310847-63gh2tg4	636	15	this	this	DT
cord-310847-63gh2tg4	636	16	process	process	NN
cord-310847-63gh2tg4	636	17	.	.	.
cord-310847-63gh2tg4	637	1	Based	base	VBN
cord-310847-63gh2tg4	637	2	on	on	IN
cord-310847-63gh2tg4	637	3	these	these	DT
cord-310847-63gh2tg4	637	4	observations	observation	NNS
cord-310847-63gh2tg4	637	5	,	,	,
cord-310847-63gh2tg4	637	6	it	-PRON-	PRP
cord-310847-63gh2tg4	637	7	has	have	VBZ
cord-310847-63gh2tg4	637	8	been	be	VBN
cord-310847-63gh2tg4	637	9	concluded	conclude	VBN
cord-310847-63gh2tg4	637	10	that	that	IN
cord-310847-63gh2tg4	637	11	the	the	DT
cord-310847-63gh2tg4	637	12	glutamic	glutamic	NN
cord-310847-63gh2tg4	637	13	acid	acid	NN
cord-310847-63gh2tg4	637	14	-	-	HYPH
cord-310847-63gh2tg4	637	15	rich	rich	JJ
cord-310847-63gh2tg4	637	16	motifs	motif	NNS
cord-310847-63gh2tg4	637	17	embedded	embed	VBN
cord-310847-63gh2tg4	637	18	into	into	IN
cord-310847-63gh2tg4	637	19	the	the	DT
cord-310847-63gh2tg4	637	20	PEVK	PEVK	NNP
cord-310847-63gh2tg4	637	21	segments	segment	NNS
cord-310847-63gh2tg4	637	22	make	make	VBP
cord-310847-63gh2tg4	637	23	titin	titin	NN
cord-310847-63gh2tg4	637	24	a	a	DT
cord-310847-63gh2tg4	637	25	calcium	calcium	NN
cord-310847-63gh2tg4	637	26	-	-	HYPH
cord-310847-63gh2tg4	637	27	dependent	dependent	JJ
cord-310847-63gh2tg4	637	28	molecular	molecular	JJ
cord-310847-63gh2tg4	637	29	spring	spring	NN
cord-310847-63gh2tg4	637	30	that	that	WDT
cord-310847-63gh2tg4	637	31	can	can	MD
cord-310847-63gh2tg4	637	32	adapt	adapt	VB
cord-310847-63gh2tg4	637	33	to	to	IN
cord-310847-63gh2tg4	637	34	the	the	DT
cord-310847-63gh2tg4	637	35	physiological	physiological	JJ
cord-310847-63gh2tg4	637	36	state	state	NN
cord-310847-63gh2tg4	637	37	of	of	IN
cord-310847-63gh2tg4	637	38	the	the	DT
cord-310847-63gh2tg4	637	39	cell	cell	NN
cord-310847-63gh2tg4	637	40	.	.	.
cord-310847-63gh2tg4	638	1	196	196	CD
cord-310847-63gh2tg4	639	1	Curiously	curiously	RB
cord-310847-63gh2tg4	639	2	,	,	,
cord-310847-63gh2tg4	639	3	titin	titin	NN
cord-310847-63gh2tg4	639	4	has	have	VBZ
cord-310847-63gh2tg4	639	5	3,193	3,193	CD
cord-310847-63gh2tg4	639	6	glutamic	glutamic	JJ
cord-310847-63gh2tg4	639	7	acids	acid	NNS
cord-310847-63gh2tg4	639	8	,	,	,
cord-310847-63gh2tg4	639	9	449	449	CD
cord-310847-63gh2tg4	639	10	of	of	IN
cord-310847-63gh2tg4	639	11	which	which	WDT
cord-310847-63gh2tg4	639	12	are	be	VBP
cord-310847-63gh2tg4	639	13	found	find	VBN
cord-310847-63gh2tg4	639	14	in	in	IN
cord-310847-63gh2tg4	639	15	the	the	DT
cord-310847-63gh2tg4	639	16	glutamic	glutamic	NN
cord-310847-63gh2tg4	639	17	acid	acid	NN
cord-310847-63gh2tg4	639	18	-	-	HYPH
cord-310847-63gh2tg4	639	19	rich	rich	JJ
cord-310847-63gh2tg4	639	20	region	region	NN
cord-310847-63gh2tg4	639	21	(	(	-LRB-
cord-310847-63gh2tg4	639	22	residues	residue	NNS
cord-310847-63gh2tg4	639	23	9974	9974	CD
cord-310847-63gh2tg4	639	24	-	-	SYM
cord-310847-63gh2tg4	639	25	11917	11917	CD
cord-310847-63gh2tg4	639	26	)	)	-RRB-
cord-310847-63gh2tg4	639	27	that	that	WDT
cord-310847-63gh2tg4	639	28	contains	contain	VBZ
cord-310847-63gh2tg4	639	29	31	31	CD
cord-310847-63gh2tg4	639	30	PEVK	PEVK	NNP
cord-310847-63gh2tg4	639	31	motifs	motif	NNS
cord-310847-63gh2tg4	639	32	.	.	.
cord-310847-63gh2tg4	640	1	Glutamates	glutamate	NNS
cord-310847-63gh2tg4	640	2	are	be	VBP
cord-310847-63gh2tg4	640	3	not	not	RB
cord-310847-63gh2tg4	640	4	evenly	evenly	RB
cord-310847-63gh2tg4	640	5	distributed	distribute	VBN
cord-310847-63gh2tg4	640	6	within	within	IN
cord-310847-63gh2tg4	640	7	the	the	DT
cord-310847-63gh2tg4	640	8	glutamic	glutamic	NN
cord-310847-63gh2tg4	640	9	acid	acid	NN
cord-310847-63gh2tg4	640	10	-	-	HYPH
cord-310847-63gh2tg4	640	11	rich	rich	JJ
cord-310847-63gh2tg4	640	12	region	region	NN
cord-310847-63gh2tg4	640	13	;	;	,
cord-310847-63gh2tg4	640	14	e.g.	e.g.	RB
cord-310847-63gh2tg4	640	15	,	,	,
cord-310847-63gh2tg4	640	16	42	42	CD
cord-310847-63gh2tg4	640	17	glutamic	glutamic	NN
cord-310847-63gh2tg4	640	18	acids	acid	NNS
cord-310847-63gh2tg4	640	19	are	be	VBP
cord-310847-63gh2tg4	640	20	concentrated	concentrate	VBN
cord-310847-63gh2tg4	640	21	within	within	IN
cord-310847-63gh2tg4	640	22	the	the	DT
cord-310847-63gh2tg4	640	23	first	first	JJ
cord-310847-63gh2tg4	640	24	116	116	CD
cord-310847-63gh2tg4	640	25	residues	residue	NNS
cord-310847-63gh2tg4	640	26	of	of	IN
cord-310847-63gh2tg4	640	27	this	this	DT
cord-310847-63gh2tg4	640	28	region	region	NN
cord-310847-63gh2tg4	640	29	(	(	-LRB-
cord-310847-63gh2tg4	640	30	residues	residue	NNS
cord-310847-63gh2tg4	640	31	9974	9974	CD
cord-310847-63gh2tg4	640	32	-	-	SYM
cord-310847-63gh2tg4	640	33	10,089	10,089	CD
cord-310847-63gh2tg4	640	34	)	)	-RRB-
cord-310847-63gh2tg4	640	35	.	.	.
cord-310847-63gh2tg4	641	1	In	in	IN
cord-310847-63gh2tg4	641	2	other	other	JJ
cord-310847-63gh2tg4	641	3	words	word	NNS
cord-310847-63gh2tg4	641	4	,	,	,
cord-310847-63gh2tg4	641	5	although	although	IN
cord-310847-63gh2tg4	641	6	the	the	DT
cord-310847-63gh2tg4	641	7	glutamic	glutamic	NN
cord-310847-63gh2tg4	641	8	acid	acid	NN
cord-310847-63gh2tg4	641	9	-	-	HYPH
cord-310847-63gh2tg4	641	10	rich	rich	JJ
cord-310847-63gh2tg4	641	11	region	region	NN
cord-310847-63gh2tg4	641	12	comprises	comprise	VBZ
cord-310847-63gh2tg4	641	13	just	just	RB
cord-310847-63gh2tg4	641	14	5.6	5.6	CD
cord-310847-63gh2tg4	641	15	%	%	NN
cord-310847-63gh2tg4	641	16	of	of	IN
cord-310847-63gh2tg4	641	17	the	the	DT
cord-310847-63gh2tg4	641	18	whole	whole	JJ
cord-310847-63gh2tg4	641	19	titin	titin	NN
cord-310847-63gh2tg4	641	20	,	,	,
cord-310847-63gh2tg4	641	21	it	-PRON-	PRP
cord-310847-63gh2tg4	641	22	has	have	VBZ
cord-310847-63gh2tg4	641	23	14.1	14.1	CD
cord-310847-63gh2tg4	641	24	%	%	NN
cord-310847-63gh2tg4	641	25	of	of	IN
cord-310847-63gh2tg4	641	26	all	all	PDT
cord-310847-63gh2tg4	641	27	the	the	DT
cord-310847-63gh2tg4	641	28	titin	titin	NN
cord-310847-63gh2tg4	641	29	's	's	POS
cord-310847-63gh2tg4	641	30	glutamates	glutamate	NNS
cord-310847-63gh2tg4	641	31	.	.	.
cord-310847-63gh2tg4	642	1	Bone	bone	NN
cord-310847-63gh2tg4	642	2	phosphoproteins	phosphoprotein	NNS
cord-310847-63gh2tg4	642	3	.	.	.
cord-310847-63gh2tg4	643	1	Bone	Bone	NNP
cord-310847-63gh2tg4	643	2	sialoprotein	sialoprotein	NNP
cord-310847-63gh2tg4	643	3	II	II	NNP
cord-310847-63gh2tg4	643	4	(	(	-LRB-
cord-310847-63gh2tg4	643	5	BSP	BSP	NNP
cord-310847-63gh2tg4	643	6	II	II	NNP
cord-310847-63gh2tg4	643	7	)	)	-RRB-
cord-310847-63gh2tg4	643	8	is	be	VBZ
cord-310847-63gh2tg4	643	9	an	an	DT
cord-310847-63gh2tg4	643	10	important	important	JJ
cord-310847-63gh2tg4	643	11	component	component	NN
cord-310847-63gh2tg4	643	12	of	of	IN
cord-310847-63gh2tg4	643	13	the	the	DT
cord-310847-63gh2tg4	643	14	bone	bone	NN
cord-310847-63gh2tg4	643	15	mineralized	mineralized	JJ
cord-310847-63gh2tg4	643	16	matrix	matrix	NN
cord-310847-63gh2tg4	643	17	.	.	.
cord-310847-63gh2tg4	644	1	This	this	DT
cord-310847-63gh2tg4	644	2	bone	bone	NN
cord-310847-63gh2tg4	644	3	-	-	HYPH
cord-310847-63gh2tg4	644	4	specific	specific	JJ
cord-310847-63gh2tg4	644	5	glycoprotein	glycoprotein	NN
cord-310847-63gh2tg4	644	6	contains	contain	VBZ
cord-310847-63gh2tg4	644	7	phosphoserine	phosphoserine	JJ
cord-310847-63gh2tg4	644	8	and	and	CC
cord-310847-63gh2tg4	644	9	sulphotyrosine	sulphotyrosine	NN
cord-310847-63gh2tg4	644	10	residues	residue	NNS
cord-310847-63gh2tg4	644	11	and	and	CC
cord-310847-63gh2tg4	644	12	two	two	CD
cord-310847-63gh2tg4	644	13	regions	region	NNS
cord-310847-63gh2tg4	644	14	of	of	IN
cord-310847-63gh2tg4	644	15	contiguous	contiguous	JJ
cord-310847-63gh2tg4	644	16	glutamic	glutamic	NN
cord-310847-63gh2tg4	644	17	acid	acid	NN
cord-310847-63gh2tg4	644	18	residues	residue	NNS
cord-310847-63gh2tg4	644	19	(	(	-LRB-
cord-310847-63gh2tg4	644	20	residues	residue	NNS
cord-310847-63gh2tg4	644	21	77	77	CD
cord-310847-63gh2tg4	644	22	-	-	SYM
cord-310847-63gh2tg4	644	23	84	84	CD
cord-310847-63gh2tg4	644	24	and	and	CC
cord-310847-63gh2tg4	644	25	156	156	CD
cord-310847-63gh2tg4	644	26	-	-	SYM
cord-310847-63gh2tg4	644	27	169	169	CD
cord-310847-63gh2tg4	644	28	)	)	-RRB-
cord-310847-63gh2tg4	644	29	.	.	.
cord-310847-63gh2tg4	645	1	In	in	IN
cord-310847-63gh2tg4	645	2	one	one	CD
cord-310847-63gh2tg4	645	3	of	of	IN
cord-310847-63gh2tg4	645	4	the	the	DT
cord-310847-63gh2tg4	645	5	first	first	JJ
cord-310847-63gh2tg4	645	6	studies	study	NNS
cord-310847-63gh2tg4	645	7	dedicated	dedicate	VBN
cord-310847-63gh2tg4	645	8	to	to	IN
cord-310847-63gh2tg4	645	9	the	the	DT
cord-310847-63gh2tg4	645	10	analysis	analysis	NN
cord-310847-63gh2tg4	645	11	of	of	IN
cord-310847-63gh2tg4	645	12	bone	bone	NN
cord-310847-63gh2tg4	645	13	phosphoprotein	phosphoprotein	NN
cord-310847-63gh2tg4	645	14	it	-PRON-	PRP
cord-310847-63gh2tg4	645	15	has	have	VBZ
cord-310847-63gh2tg4	645	16	been	be	VBN
cord-310847-63gh2tg4	645	17	shown	show	VBN
cord-310847-63gh2tg4	645	18	that	that	IN
cord-310847-63gh2tg4	645	19	this	this	DT
cord-310847-63gh2tg4	645	20	glycoprotein	glycoprotein	NN
cord-310847-63gh2tg4	645	21	can	can	MD
cord-310847-63gh2tg4	645	22	be	be	VB
cord-310847-63gh2tg4	645	23	purified	purify	VBN
cord-310847-63gh2tg4	645	24	from	from	IN
cord-310847-63gh2tg4	645	25	the	the	DT
cord-310847-63gh2tg4	645	26	mixture	mixture	NN
cord-310847-63gh2tg4	645	27	of	of	IN
cord-310847-63gh2tg4	645	28	proteins	protein	NNS
cord-310847-63gh2tg4	645	29	extracted	extract	VBN
cord-310847-63gh2tg4	645	30	by	by	IN
cord-310847-63gh2tg4	645	31	demineralization	demineralization	NN
cord-310847-63gh2tg4	645	32	of	of	IN
cord-310847-63gh2tg4	645	33	rat	rat	NN
cord-310847-63gh2tg4	645	34	bone	bone	NN
cord-310847-63gh2tg4	645	35	with	with	IN
cord-310847-63gh2tg4	645	36	0.5	0.5	CD
cord-310847-63gh2tg4	645	37	M	M	NNP
cord-310847-63gh2tg4	645	38	EDTA	EDTA	NNP
cord-310847-63gh2tg4	645	39	in	in	IN
cord-310847-63gh2tg4	645	40	4	4	CD
cord-310847-63gh2tg4	645	41	M	M	NNP
cord-310847-63gh2tg4	645	42	guanidinium	guanidinium	NN
cord-310847-63gh2tg4	645	43	chloride	chloride	NN
cord-310847-63gh2tg4	645	44	.	.	.
cord-310847-63gh2tg4	646	1	197	197	CD
cord-310847-63gh2tg4	647	1	It	-PRON-	PRP
cord-310847-63gh2tg4	647	2	was	be	VBD
cord-310847-63gh2tg4	647	3	also	also	RB
cord-310847-63gh2tg4	647	4	emphasized	emphasize	VBN
cord-310847-63gh2tg4	647	5	that	that	IN
cord-310847-63gh2tg4	647	6	this	this	DT
cord-310847-63gh2tg4	647	7	protein	protein	NN
cord-310847-63gh2tg4	647	8	possessed	possess	VBD
cord-310847-63gh2tg4	647	9	an	an	DT
cord-310847-63gh2tg4	647	10	abnormal	abnormal	JJ
cord-310847-63gh2tg4	647	11	electrophoretic	electrophoretic	JJ
cord-310847-63gh2tg4	647	12	mobility	mobility	NN
cord-310847-63gh2tg4	647	13	This	this	DT
cord-310847-63gh2tg4	647	14	protein	protein	NN
cord-310847-63gh2tg4	647	15	was	be	VBD
cord-310847-63gh2tg4	647	16	shown	show	VBN
cord-310847-63gh2tg4	647	17	to	to	TO
cord-310847-63gh2tg4	647	18	be	be	VB
cord-310847-63gh2tg4	647	19	involved	involve	VBN
cord-310847-63gh2tg4	647	20	in	in	IN
cord-310847-63gh2tg4	647	21	sensing	sense	VBG
cord-310847-63gh2tg4	647	22	infertile	infertile	JJ
cord-310847-63gh2tg4	647	23	nutrient	nutrient	NN
cord-310847-63gh2tg4	647	24	conditions	condition	NNS
cord-310847-63gh2tg4	647	25	in	in	IN
cord-310847-63gh2tg4	647	26	infected	infected	JJ
cord-310847-63gh2tg4	647	27	cells	cell	NNS
cord-310847-63gh2tg4	647	28	to	to	TO
cord-310847-63gh2tg4	647	29	promote	promote	VB
cord-310847-63gh2tg4	647	30	a	a	DT
cord-310847-63gh2tg4	647	31	transfer	transfer	NN
cord-310847-63gh2tg4	647	32	from	from	IN
cord-310847-63gh2tg4	647	33	saprophytic	saprophytic	NN
cord-310847-63gh2tg4	647	34	to	to	IN
cord-310847-63gh2tg4	647	35	dormant	dormant	JJ
cord-310847-63gh2tg4	647	36	microsclerotia	microsclerotia	NN
cord-310847-63gh2tg4	647	37	for	for	IN
cord-310847-63gh2tg4	647	38	long	long	JJ
cord-310847-63gh2tg4	647	39	-	-	HYPH
cord-310847-63gh2tg4	647	40	term	term	NN
cord-310847-63gh2tg4	647	41	survival	survival	NN
cord-310847-63gh2tg4	647	42	.	.	.
cord-310847-63gh2tg4	648	1	213	213	CD
cord-310847-63gh2tg4	648	2	VdGARP1	VdGARP1	NNP
cord-310847-63gh2tg4	648	3	is	be	VBZ
cord-310847-63gh2tg4	648	4	a	a	DT
cord-310847-63gh2tg4	648	5	short	short	JJ
cord-310847-63gh2tg4	648	6	(	(	-LRB-
cord-310847-63gh2tg4	648	7	91	91	CD
cord-310847-63gh2tg4	648	8	residues	residue	NNS
cord-310847-63gh2tg4	648	9	)	)	-RRB-
cord-310847-63gh2tg4	648	10	extremely	extremely	RB
cord-310847-63gh2tg4	648	11	acidic	acidic	JJ
cord-310847-63gh2tg4	648	12	protein	protein	NN
cord-310847-63gh2tg4	648	13	with	with	IN
cord-310847-63gh2tg4	648	14	a	a	DT
cord-310847-63gh2tg4	648	15	pI	pi	NN
cord-310847-63gh2tg4	648	16	of	of	IN
cord-310847-63gh2tg4	648	17	3.3	3.3	CD
cord-310847-63gh2tg4	648	18	that	that	WDT
cord-310847-63gh2tg4	648	19	contains	contain	VBZ
cord-310847-63gh2tg4	648	20	52.8	52.8	CD
cord-310847-63gh2tg4	648	21	%	%	NN
cord-310847-63gh2tg4	648	22	negatively	negatively	RB
cord-310847-63gh2tg4	648	23	charged	charge	VBN
cord-310847-63gh2tg4	648	24	residues	residue	NNS
cord-310847-63gh2tg4	648	25	(	(	-LRB-
cord-310847-63gh2tg4	648	26	31	31	CD
cord-310847-63gh2tg4	648	27	glutamic	glutamic	JJ
cord-310847-63gh2tg4	648	28	acids	acid	NNS
cord-310847-63gh2tg4	648	29	and	and	CC
cord-310847-63gh2tg4	648	30	17	17	CD
cord-310847-63gh2tg4	648	31	aspartic	aspartic	JJ
cord-310847-63gh2tg4	648	32	acids	acid	NNS
cord-310847-63gh2tg4	648	33	)	)	-RRB-
cord-310847-63gh2tg4	648	34	.	.	.
cord-310847-63gh2tg4	649	1	There	there	EX
cord-310847-63gh2tg4	649	2	are	be	VBP
cord-310847-63gh2tg4	649	3	also	also	RB
cord-310847-63gh2tg4	649	4	several	several	JJ
cord-310847-63gh2tg4	649	5	other	other	JJ
cord-310847-63gh2tg4	649	6	GARPs	garp	NNS
cord-310847-63gh2tg4	649	7	in	in	IN
cord-310847-63gh2tg4	649	8	various	various	JJ
cord-310847-63gh2tg4	649	9	organisms	organism	NNS
cord-310847-63gh2tg4	649	10	,	,	,
cord-310847-63gh2tg4	649	11	the	the	DT
cord-310847-63gh2tg4	649	12	functions	function	NNS
cord-310847-63gh2tg4	649	13	of	of	IN
cord-310847-63gh2tg4	649	14	which	which	WDT
cord-310847-63gh2tg4	649	15	are	be	VBP
cord-310847-63gh2tg4	649	16	not	not	RB
cord-310847-63gh2tg4	649	17	known	know	VBN
cord-310847-63gh2tg4	649	18	as	as	IN
cord-310847-63gh2tg4	649	19	of	of	IN
cord-310847-63gh2tg4	649	20	yet	yet	RB
cord-310847-63gh2tg4	649	21	.	.	.
cord-310847-63gh2tg4	650	1	Small	small	JJ
cord-310847-63gh2tg4	650	2	GARP	GARP	NNP
cord-310847-63gh2tg4	650	3	(	(	-LRB-
cord-310847-63gh2tg4	650	4	a	a	DT
cord-310847-63gh2tg4	650	5	112-amino	112-amino	CD
cord-310847-63gh2tg4	650	6	acid	acid	NN
cord-310847-63gh2tg4	650	7	protein	protein	NN
cord-310847-63gh2tg4	650	8	,	,	,
cord-310847-63gh2tg4	650	9	with	with	IN
cord-310847-63gh2tg4	650	10	a	a	DT
cord-310847-63gh2tg4	650	11	molecular	molecular	JJ
cord-310847-63gh2tg4	650	12	mass	mass	NN
cord-310847-63gh2tg4	650	13	of	of	IN
cord-310847-63gh2tg4	650	14	13.1	13.1	CD
cord-310847-63gh2tg4	650	15	kDa	kDa	NNPS
cord-310847-63gh2tg4	650	16	and	and	CC
cord-310847-63gh2tg4	650	17	an	an	DT
cord-310847-63gh2tg4	650	18	isoelectric	isoelectric	JJ
cord-310847-63gh2tg4	650	19	point	point	NN
cord-310847-63gh2tg4	650	20	of	of	IN
cord-310847-63gh2tg4	650	21	3.94	3.94	CD
cord-310847-63gh2tg4	650	22	,	,	,
cord-310847-63gh2tg4	650	23	29	29	CD
cord-310847-63gh2tg4	650	24	residues	residue	NNS
cord-310847-63gh2tg4	650	25	of	of	IN
cord-310847-63gh2tg4	650	26	which	which	WDT
cord-310847-63gh2tg4	650	27	are	be	VBP
cord-310847-63gh2tg4	650	28	glutamic	glutamic	JJ
cord-310847-63gh2tg4	650	29	acids	acid	NNS
cord-310847-63gh2tg4	650	30	)	)	-RRB-
cord-310847-63gh2tg4	650	31	was	be	VBD
cord-310847-63gh2tg4	650	32	found	find	VBN
cord-310847-63gh2tg4	650	33	in	in	IN
cord-310847-63gh2tg4	650	34	Euplotes	Euplotes	NNP
cord-310847-63gh2tg4	650	35	octocarinatus	octocarinatus	NN
cord-310847-63gh2tg4	650	36	.	.	.
cord-310847-63gh2tg4	651	1	214	214	CD
cord-310847-63gh2tg4	652	1	Plasmodium	plasmodium	NN
cord-310847-63gh2tg4	652	2	falciparum	falciparum	NN
cord-310847-63gh2tg4	652	3	GARP	GARP	NNP
cord-310847-63gh2tg4	652	4	consists	consist	VBZ
cord-310847-63gh2tg4	652	5	of	of	IN
cord-310847-63gh2tg4	652	6	679	679	CD
cord-310847-63gh2tg4	652	7	residues	residue	NNS
cord-310847-63gh2tg4	652	8	,	,	,
cord-310847-63gh2tg4	652	9	169	169	CD
cord-310847-63gh2tg4	652	10	of	of	IN
cord-310847-63gh2tg4	652	11	which	which	WDT
cord-310847-63gh2tg4	652	12	are	be	VBP
cord-310847-63gh2tg4	652	13	glutamic	glutamic	JJ
cord-310847-63gh2tg4	652	14	acids	acid	NNS
cord-310847-63gh2tg4	652	15	.	.	.
cord-310847-63gh2tg4	653	1	215	215	CD
cord-310847-63gh2tg4	653	2	Rhox8	rhox8	JJ
cord-310847-63gh2tg4	653	3	/	/	SYM
cord-310847-63gh2tg4	653	4	Tox	Tox	NNP
cord-310847-63gh2tg4	653	5	.	.	.
cord-310847-63gh2tg4	654	1	Reproductive	reproductive	JJ
cord-310847-63gh2tg4	654	2	homeobox	homeobox	NN
cord-310847-63gh2tg4	654	3	8	8	CD
cord-310847-63gh2tg4	654	4	protein	protein	NN
cord-310847-63gh2tg4	654	5	(	(	-LRB-
cord-310847-63gh2tg4	654	6	Rhox8	rhox8	JJ
cord-310847-63gh2tg4	654	7	or	or	CC
cord-310847-63gh2tg4	654	8	Tox	Tox	NNP
cord-310847-63gh2tg4	654	9	)	)	-RRB-
cord-310847-63gh2tg4	654	10	is	be	VBZ
cord-310847-63gh2tg4	654	11	a	a	DT
cord-310847-63gh2tg4	654	12	homeodomain	homeodomain	NN
cord-310847-63gh2tg4	654	13	protein	protein	NN
cord-310847-63gh2tg4	654	14	which	which	WDT
cord-310847-63gh2tg4	654	15	is	be	VBZ
cord-310847-63gh2tg4	654	16	distantly	distantly	RB
cord-310847-63gh2tg4	654	17	related	relate	VBN
cord-310847-63gh2tg4	654	18	to	to	IN
cord-310847-63gh2tg4	654	19	the	the	DT
cord-310847-63gh2tg4	654	20	members	member	NNS
cord-310847-63gh2tg4	654	21	of	of	IN
cord-310847-63gh2tg4	654	22	the	the	DT
cord-310847-63gh2tg4	654	23	Paired	Paired	NNP
cord-310847-63gh2tg4	654	24	/	/	SYM
cord-310847-63gh2tg4	654	25	Pax	Pax	NNP
cord-310847-63gh2tg4	654	26	family	family	NN
cord-310847-63gh2tg4	654	27	belonging	belong	VBG
cord-310847-63gh2tg4	654	28	to	to	IN
cord-310847-63gh2tg4	654	29	the	the	DT
cord-310847-63gh2tg4	654	30	PEPP	PEPP	NNP
cord-310847-63gh2tg4	654	31	subfamily	subfamily	NN
cord-310847-63gh2tg4	654	32	of	of	IN
cord-310847-63gh2tg4	654	33	Paired	Paired	NNP
cord-310847-63gh2tg4	654	34	-	-	HYPH
cord-310847-63gh2tg4	654	35	like	like	JJ
cord-310847-63gh2tg4	654	36	homeobox	homeobox	NN
cord-310847-63gh2tg4	654	37	proteins	protein	NNS
cord-310847-63gh2tg4	654	38	.	.	.
cord-310847-63gh2tg4	655	1	216	216	CD
cord-310847-63gh2tg4	656	1	In	in	IN
cord-310847-63gh2tg4	656	2	mice	mouse	NNS
cord-310847-63gh2tg4	656	3	,	,	,
cord-310847-63gh2tg4	656	4	Tox	Tox	NNP
cord-310847-63gh2tg4	656	5	is	be	VBZ
cord-310847-63gh2tg4	656	6	predominately	predominately	RB
cord-310847-63gh2tg4	656	7	transcribed	transcribe	VBN
cord-310847-63gh2tg4	656	8	in	in	IN
cord-310847-63gh2tg4	656	9	the	the	DT
cord-310847-63gh2tg4	656	10	testis	testis	NN
cord-310847-63gh2tg4	656	11	and	and	CC
cord-310847-63gh2tg4	656	12	ovary	ovary	NN
cord-310847-63gh2tg4	656	13	and	and	CC
cord-310847-63gh2tg4	656	14	potentially	potentially	RB
cord-310847-63gh2tg4	656	15	plays	play	VBZ
cord-310847-63gh2tg4	656	16	an	an	DT
cord-310847-63gh2tg4	656	17	important	important	JJ
cord-310847-63gh2tg4	656	18	role	role	NN
cord-310847-63gh2tg4	656	19	during	during	IN
cord-310847-63gh2tg4	656	20	gametogenesis	gametogenesis	NNP
cord-310847-63gh2tg4	656	21	.	.	.
cord-310847-63gh2tg4	657	1	216	216	CD
cord-310847-63gh2tg4	658	1	This	this	DT
cord-310847-63gh2tg4	658	2	320	320	CD
cord-310847-63gh2tg4	658	3	residues	residue	NNS
cord-310847-63gh2tg4	658	4	-	-	HYPH
cord-310847-63gh2tg4	658	5	long	long	JJ
cord-310847-63gh2tg4	658	6	protein	protein	NN
cord-310847-63gh2tg4	658	7	contains	contain	VBZ
cord-310847-63gh2tg4	658	8	113	113	CD
cord-310847-63gh2tg4	658	9	glutamic	glutamic	NN
cord-310847-63gh2tg4	658	10	acids	acid	NNS
cord-310847-63gh2tg4	658	11	organized	organize	VBN
cord-310847-63gh2tg4	658	12	in	in	IN
cord-310847-63gh2tg4	658	13	two	two	CD
cord-310847-63gh2tg4	658	14	poly	poly	JJ
cord-310847-63gh2tg4	658	15	-	-	HYPH
cord-310847-63gh2tg4	658	16	glutamic	glutamic	NN
cord-310847-63gh2tg4	658	17	acid	acid	NN
cord-310847-63gh2tg4	658	18	stretches	stretch	NNS
cord-310847-63gh2tg4	658	19	(	(	-LRB-
cord-310847-63gh2tg4	658	20	residues	residue	NNS
cord-310847-63gh2tg4	658	21	111	111	CD
cord-310847-63gh2tg4	658	22	-	-	SYM
cord-310847-63gh2tg4	658	23	139	139	CD
cord-310847-63gh2tg4	658	24	and	and	CC
cord-310847-63gh2tg4	658	25	177	177	CD
cord-310847-63gh2tg4	658	26	-	-	SYM
cord-310847-63gh2tg4	658	27	201	201	CD
cord-310847-63gh2tg4	658	28	)	)	-RRB-
cord-310847-63gh2tg4	658	29	and	and	CC
cord-310847-63gh2tg4	658	30	several	several	JJ
cord-310847-63gh2tg4	658	31	Glu	Glu	NNP
cord-310847-63gh2tg4	658	32	-	-	HYPH
cord-310847-63gh2tg4	658	33	rich	rich	JJ
cord-310847-63gh2tg4	658	34	regions	region	NNS
cord-310847-63gh2tg4	658	35	,	,	,
cord-310847-63gh2tg4	658	36	which	which	WDT
cord-310847-63gh2tg4	658	37	together	together	RB
cord-310847-63gh2tg4	658	38	with	with	IN
cord-310847-63gh2tg4	658	39	11	11	CD
cord-310847-63gh2tg4	658	40	aspartic	aspartic	JJ
cord-310847-63gh2tg4	658	41	acids	acid	NNS
cord-310847-63gh2tg4	658	42	makes	make	VBZ
cord-310847-63gh2tg4	658	43	Rhox8	rhox8	JJ
cord-310847-63gh2tg4	658	44	highly	highly	RB
cord-310847-63gh2tg4	658	45	acidic	acidic	JJ
cord-310847-63gh2tg4	658	46	(	(	-LRB-
cord-310847-63gh2tg4	658	47	pI	pI	NNP
cord-310847-63gh2tg4	658	48	3.95	3.95	CD
cord-310847-63gh2tg4	658	49	)	)	-RRB-
cord-310847-63gh2tg4	658	50	.	.	.
cord-310847-63gh2tg4	659	1	KIBRA	KIBRA	NNP
cord-310847-63gh2tg4	659	2	.	.	.
cord-310847-63gh2tg4	660	1	Kidney	kidney	NN
cord-310847-63gh2tg4	660	2	and	and	CC
cord-310847-63gh2tg4	660	3	brain	brain	NN
cord-310847-63gh2tg4	660	4	protein	protein	NN
cord-310847-63gh2tg4	660	5	(	(	-LRB-
cord-310847-63gh2tg4	660	6	KIBRA	KIBRA	NNP
cord-310847-63gh2tg4	660	7	)	)	-RRB-
cord-310847-63gh2tg4	660	8	is	be	VBZ
cord-310847-63gh2tg4	660	9	a	a	DT
cord-310847-63gh2tg4	660	10	large	large	JJ
cord-310847-63gh2tg4	660	11	(	(	-LRB-
cord-310847-63gh2tg4	660	12	1,113	1,113	CD
cord-310847-63gh2tg4	660	13	residues	residue	NNS
cord-310847-63gh2tg4	660	14	)	)	-RRB-
cord-310847-63gh2tg4	660	15	protein	protein	NN
cord-310847-63gh2tg4	660	16	that	that	WDT
cord-310847-63gh2tg4	660	17	serves	serve	VBZ
cord-310847-63gh2tg4	660	18	as	as	IN
cord-310847-63gh2tg4	660	19	a	a	DT
cord-310847-63gh2tg4	660	20	potential	potential	JJ
cord-310847-63gh2tg4	660	21	regulator	regulator	NN
cord-310847-63gh2tg4	660	22	of	of	IN
cord-310847-63gh2tg4	660	23	the	the	DT
cord-310847-63gh2tg4	660	24	Hippo/	Hippo/	NNP
cord-310847-63gh2tg4	660	25	SWH	SWH	NNP
cord-310847-63gh2tg4	660	26	(	(	-LRB-
cord-310847-63gh2tg4	660	27	Sav	Sav	NNP
cord-310847-63gh2tg4	660	28	/	/	SYM
cord-310847-63gh2tg4	660	29	Wts	Wts	NNP
cord-310847-63gh2tg4	660	30	/	/	SYM
cord-310847-63gh2tg4	660	31	Hpo	Hpo	NNP
cord-310847-63gh2tg4	660	32	or	or	CC
cord-310847-63gh2tg4	660	33	Salvador	Salvador	NNP
cord-310847-63gh2tg4	660	34	/	/	SYM
cord-310847-63gh2tg4	660	35	Warts	Warts	NNP
cord-310847-63gh2tg4	660	36	/	/	SYM
cord-310847-63gh2tg4	660	37	Hippo	Hippo	NNP
cord-310847-63gh2tg4	660	38	)	)	-RRB-
cord-310847-63gh2tg4	660	39	signaling	signal	VBG
cord-310847-63gh2tg4	660	40	pathway	pathway	NN
cord-310847-63gh2tg4	660	41	that	that	WDT
cord-310847-63gh2tg4	660	42	restricts	restrict	VBZ
cord-310847-63gh2tg4	660	43	proliferation	proliferation	NN
cord-310847-63gh2tg4	660	44	and	and	CC
cord-310847-63gh2tg4	660	45	promotes	promote	VBZ
cord-310847-63gh2tg4	660	46	apoptosis	apoptosis	NN
cord-310847-63gh2tg4	660	47	therefore	therefore	RB
cord-310847-63gh2tg4	660	48	being	be	VBG
cord-310847-63gh2tg4	660	49	crucial	crucial	JJ
cord-310847-63gh2tg4	660	50	for	for	IN
cord-310847-63gh2tg4	660	51	tumor	tumor	NN
cord-310847-63gh2tg4	660	52	suppression	suppression	NN
cord-310847-63gh2tg4	660	53	.	.	.
cord-310847-63gh2tg4	661	1	217	217	CD
cord-310847-63gh2tg4	661	2	,	,	,
cord-310847-63gh2tg4	661	3	218	218	CD
cord-310847-63gh2tg4	661	4	KIBRA	KIBRA	NNP
cord-310847-63gh2tg4	661	5	has	have	VBZ
cord-310847-63gh2tg4	661	6	111	111	CD
cord-310847-63gh2tg4	661	7	glutamic	glutamic	NN
cord-310847-63gh2tg4	661	8	acids	acid	NNS
cord-310847-63gh2tg4	661	9	and	and	CC
cord-310847-63gh2tg4	661	10	possesses	possess	VBZ
cord-310847-63gh2tg4	661	11	two	two	CD
cord-310847-63gh2tg4	661	12	N	n	CD
cord-310847-63gh2tg4	661	13	-	-	HYPH
cord-310847-63gh2tg4	661	14	terminal	terminal	NN
cord-310847-63gh2tg4	661	15	WW	WW	NNP
cord-310847-63gh2tg4	661	16	domains	domain	NNS
cord-310847-63gh2tg4	661	17	,	,	,
cord-310847-63gh2tg4	661	18	an	an	DT
cord-310847-63gh2tg4	661	19	internal	internal	JJ
cord-310847-63gh2tg4	661	20	C2-like	c2-like	NN
cord-310847-63gh2tg4	661	21	domain	domain	NN
cord-310847-63gh2tg4	661	22	and	and	CC
cord-310847-63gh2tg4	661	23	a	a	DT
cord-310847-63gh2tg4	661	24	C	c	NN
cord-310847-63gh2tg4	661	25	-	-	HYPH
cord-310847-63gh2tg4	661	26	terminal	terminal	NN
cord-310847-63gh2tg4	661	27	Glu	Glu	NNP
cord-310847-63gh2tg4	661	28	-	-	HYPH
cord-310847-63gh2tg4	661	29	rich	rich	JJ
cord-310847-63gh2tg4	661	30	stretch	stretch	NN
cord-310847-63gh2tg4	661	31	(	(	-LRB-
cord-310847-63gh2tg4	661	32	residues	residue	NNS
cord-310847-63gh2tg4	661	33	819	819	CD
cord-310847-63gh2tg4	661	34	-	-	SYM
cord-310847-63gh2tg4	661	35	873	873	CD
cord-310847-63gh2tg4	661	36	)	)	-RRB-
cord-310847-63gh2tg4	661	37	.	.	.
cord-310847-63gh2tg4	662	1	219	219	CD
cord-310847-63gh2tg4	662	2	Cellular	cellular	JJ
cord-310847-63gh2tg4	662	3	functions	function	NNS
cord-310847-63gh2tg4	662	4	of	of	IN
cord-310847-63gh2tg4	662	5	KIBRA	KIBRA	NNP
cord-310847-63gh2tg4	662	6	are	be	VBP
cord-310847-63gh2tg4	662	7	modulated	modulate	VBN
cord-310847-63gh2tg4	662	8	via	via	IN
cord-310847-63gh2tg4	662	9	phosphorylation	phosphorylation	NN
cord-310847-63gh2tg4	662	10	by	by	IN
cord-310847-63gh2tg4	662	11	protein	protein	NN
cord-310847-63gh2tg4	662	12	kinase	kinase	NN
cord-310847-63gh2tg4	662	13	C	C	NNP
cord-310847-63gh2tg4	662	14	zeta	zeta	NN
cord-310847-63gh2tg4	662	15	(	(	-LRB-
cord-310847-63gh2tg4	662	16	PRKCZ	PRKCZ	NNP
cord-310847-63gh2tg4	662	17	)	)	-RRB-
cord-310847-63gh2tg4	662	18	.	.	.
cord-310847-63gh2tg4	663	1	220	220	CD
cord-310847-63gh2tg4	664	1	Some	some	DT
cord-310847-63gh2tg4	664	2	cellular	cellular	JJ
cord-310847-63gh2tg4	664	3	activities	activity	NNS
cord-310847-63gh2tg4	664	4	of	of	IN
cord-310847-63gh2tg4	664	5	KIBRA	KIBRA	NNP
cord-310847-63gh2tg4	664	6	may	may	MD
cord-310847-63gh2tg4	664	7	be	be	VB
cord-310847-63gh2tg4	664	8	associated	associate	VBN
cord-310847-63gh2tg4	664	9	with	with	IN
cord-310847-63gh2tg4	664	10	memory	memory	NN
cord-310847-63gh2tg4	664	11	performance	performance	NN
cord-310847-63gh2tg4	664	12	.	.	.
cord-310847-63gh2tg4	665	1	220	220	CD
cord-310847-63gh2tg4	665	2	,	,	,
cord-310847-63gh2tg4	665	3	221	221	CD
cord-310847-63gh2tg4	665	4	Furthermore	furthermore	RB
cord-310847-63gh2tg4	665	5	,	,	,
cord-310847-63gh2tg4	665	6	in	in	IN
cord-310847-63gh2tg4	665	7	mammalian	mammalian	JJ
cord-310847-63gh2tg4	665	8	cells	cell	NNS
cord-310847-63gh2tg4	665	9	,	,	,
cord-310847-63gh2tg4	665	10	this	this	DT
cord-310847-63gh2tg4	665	11	protein	protein	NN
cord-310847-63gh2tg4	665	12	co	co	VBD
cord-310847-63gh2tg4	665	13	-	-	VBD
cord-310847-63gh2tg4	665	14	activates	activate	VBZ
cord-310847-63gh2tg4	665	15	functions	function	NNS
cord-310847-63gh2tg4	665	16	of	of	IN
cord-310847-63gh2tg4	665	17	the	the	DT
cord-310847-63gh2tg4	665	18	dynein	dynein	JJ
cord-310847-63gh2tg4	665	19	light	light	JJ
cord-310847-63gh2tg4	665	20	chain	chain	NN
cord-310847-63gh2tg4	665	21	1	1	CD
cord-310847-63gh2tg4	665	22	,	,	,
cord-310847-63gh2tg4	665	23	222	222	CD
cord-310847-63gh2tg4	665	24	is	be	VBZ
cord-310847-63gh2tg4	665	25	involved	involve	VBN
cord-310847-63gh2tg4	665	26	in	in	IN
cord-310847-63gh2tg4	665	27	regulation	regulation	NN
cord-310847-63gh2tg4	665	28	of	of	IN
cord-310847-63gh2tg4	665	29	the	the	DT
cord-310847-63gh2tg4	665	30	collagen	collagen	NN
cord-310847-63gh2tg4	665	31	-	-	HYPH
cord-310847-63gh2tg4	665	32	stimulated	stimulate	VBN
cord-310847-63gh2tg4	665	33	activation	activation	NN
cord-310847-63gh2tg4	665	34	of	of	IN
cord-310847-63gh2tg4	665	35	the	the	DT
cord-310847-63gh2tg4	665	36	ERK/	ERK/	NNP
cord-310847-63gh2tg4	665	37	MAPK	MAPK	NNP
cord-310847-63gh2tg4	665	38	cascade	cascade	VBP
cord-310847-63gh2tg4	665	39	223	223	CD
cord-310847-63gh2tg4	665	40	and	and	CC
cord-310847-63gh2tg4	665	41	modulates	modulate	VBZ
cord-310847-63gh2tg4	665	42	directional	directional	JJ
cord-310847-63gh2tg4	665	43	migration	migration	NN
cord-310847-63gh2tg4	665	44	of	of	IN
cord-310847-63gh2tg4	665	45	podocytes	podocyte	NNS
cord-310847-63gh2tg4	665	46	.	.	.
cord-310847-63gh2tg4	666	1	224	224	CD
cord-310847-63gh2tg4	666	2	KIBRA	KIBRA	NNP
cord-310847-63gh2tg4	666	3	interacts	interact	VBZ
cord-310847-63gh2tg4	666	4	with	with	IN
cord-310847-63gh2tg4	666	5	histone	histone	NN
cord-310847-63gh2tg4	666	6	H3	H3	NNP
cord-310847-63gh2tg4	666	7	via	via	IN
cord-310847-63gh2tg4	666	8	its	-PRON-	PRP$
cord-310847-63gh2tg4	666	9	Glu	Glu	NNP
cord-310847-63gh2tg4	666	10	-	-	HYPH
cord-310847-63gh2tg4	666	11	rich	rich	JJ
cord-310847-63gh2tg4	666	12	region	region	NN
cord-310847-63gh2tg4	666	13	,	,	,
cord-310847-63gh2tg4	666	14	and	and	CC
cord-310847-63gh2tg4	666	15	this	this	DT
cord-310847-63gh2tg4	666	16	interaction	interaction	NN
cord-310847-63gh2tg4	666	17	might	may	MD
cord-310847-63gh2tg4	666	18	play	play	VB
cord-310847-63gh2tg4	666	19	an	an	DT
cord-310847-63gh2tg4	666	20	important	important	JJ
cord-310847-63gh2tg4	666	21	role	role	NN
cord-310847-63gh2tg4	666	22	in	in	IN
cord-310847-63gh2tg4	666	23	conferring	confer	VBG
cord-310847-63gh2tg4	666	24	an	an	DT
cord-310847-63gh2tg4	666	25	optimal	optimal	JJ
cord-310847-63gh2tg4	666	26	transactivation	transactivation	NN
cord-310847-63gh2tg4	666	27	function	function	NN
cord-310847-63gh2tg4	666	28	to	to	IN
cord-310847-63gh2tg4	666	29	the	the	DT
cord-310847-63gh2tg4	666	30	estrogen	estrogen	NN
cord-310847-63gh2tg4	666	31	receptor	receptor	NN
cord-310847-63gh2tg4	666	32	-	-	HYPH
cord-310847-63gh2tg4	666	33	α	α	NN
cord-310847-63gh2tg4	666	34	(	(	-LRB-
cord-310847-63gh2tg4	666	35	ER	ER	NNP
cord-310847-63gh2tg4	666	36	)	)	-RRB-
cord-310847-63gh2tg4	666	37	and	and	CC
cord-310847-63gh2tg4	666	38	also	also	RB
cord-310847-63gh2tg4	666	39	may	may	MD
cord-310847-63gh2tg4	666	40	be	be	VB
cord-310847-63gh2tg4	666	41	involved	involve	VBN
cord-310847-63gh2tg4	666	42	in	in	IN
cord-310847-63gh2tg4	666	43	the	the	DT
cord-310847-63gh2tg4	666	44	proliferation	proliferation	NN
cord-310847-63gh2tg4	666	45	of	of	IN
cord-310847-63gh2tg4	666	46	ligand	ligand	NN
cord-310847-63gh2tg4	666	47	-	-	HYPH
cord-310847-63gh2tg4	666	48	stimulated	stimulate	VBN
cord-310847-63gh2tg4	666	49	breast	breast	NN
cord-310847-63gh2tg4	666	50	cancer	cancer	NN
cord-310847-63gh2tg4	666	51	cells	cell	NNS
cord-310847-63gh2tg4	666	52	.	.	.
cord-310847-63gh2tg4	667	1	222	222	CD
cord-310847-63gh2tg4	668	1	SH3BGR	SH3BGR	NNP
cord-310847-63gh2tg4	668	2	.	.	.
cord-310847-63gh2tg4	669	1	SH3	SH3	NNP
cord-310847-63gh2tg4	669	2	domain	domain	NN
cord-310847-63gh2tg4	669	3	-	-	HYPH
cord-310847-63gh2tg4	669	4	binding	bind	VBG
cord-310847-63gh2tg4	669	5	glutamic	glutamic	NN
cord-310847-63gh2tg4	669	6	acid	acid	NN
cord-310847-63gh2tg4	669	7	-	-	HYPH
cord-310847-63gh2tg4	669	8	rich	rich	JJ
cord-310847-63gh2tg4	669	9	protein	protein	NN
cord-310847-63gh2tg4	669	10	(	(	-LRB-
cord-310847-63gh2tg4	669	11	SH3BGR	SH3BGR	NNP
cord-310847-63gh2tg4	669	12	)	)	-RRB-
cord-310847-63gh2tg4	669	13	is	be	VBZ
cord-310847-63gh2tg4	669	14	a	a	DT
cord-310847-63gh2tg4	669	15	highly	highly	RB
cord-310847-63gh2tg4	669	16	acidic	acidic	JJ
cord-310847-63gh2tg4	669	17	(	(	-LRB-
cord-310847-63gh2tg4	669	18	pI	pI	NNP
cord-310847-63gh2tg4	669	19	4.09	4.09	CD
cord-310847-63gh2tg4	669	20	)	)	-RRB-
cord-310847-63gh2tg4	669	21	239	239	CD
cord-310847-63gh2tg4	669	22	residues	residue	NNS
cord-310847-63gh2tg4	669	23	-	-	:
cord-310847-63gh2tg4	669	24	long	long	JJ
cord-310847-63gh2tg4	669	25	protein	protein	NN
cord-310847-63gh2tg4	669	26	that	that	WDT
cord-310847-63gh2tg4	669	27	possesses	possess	VBZ
cord-310847-63gh2tg4	669	28	44	44	CD
cord-310847-63gh2tg4	669	29	glutamates	glutamate	NNS
cord-310847-63gh2tg4	669	30	and	and	CC
cord-310847-63gh2tg4	669	31	15	15	CD
cord-310847-63gh2tg4	669	32	aspartates	aspartate	NNS
cord-310847-63gh2tg4	669	33	and	and	CC
cord-310847-63gh2tg4	669	34	that	that	WDT
cord-310847-63gh2tg4	669	35	is	be	VBZ
cord-310847-63gh2tg4	669	36	expressed	express	VBN
cord-310847-63gh2tg4	669	37	in	in	IN
cord-310847-63gh2tg4	669	38	heart	heart	NN
cord-310847-63gh2tg4	669	39	and	and	CC
cord-310847-63gh2tg4	669	40	skeletal	skeletal	JJ
cord-310847-63gh2tg4	669	41	muscles	muscle	NNS
cord-310847-63gh2tg4	669	42	.	.	.
cord-310847-63gh2tg4	670	1	225	225	CD
cord-310847-63gh2tg4	671	1	The	the	DT
cord-310847-63gh2tg4	671	2	majority	majority	NN
cord-310847-63gh2tg4	671	3	of	of	IN
cord-310847-63gh2tg4	671	4	glutamates	glutamate	NNS
cord-310847-63gh2tg4	671	5	are	be	VBP
cord-310847-63gh2tg4	671	6	located	locate	VBN
cord-310847-63gh2tg4	671	7	within	within	IN
cord-310847-63gh2tg4	671	8	the	the	DT
cord-310847-63gh2tg4	671	9	C	C	NNP
cord-310847-63gh2tg4	671	10	-	-	HYPH
cord-310847-63gh2tg4	671	11	terminal	terminal	NN
cord-310847-63gh2tg4	671	12	Glu	Glu	NNP
cord-310847-63gh2tg4	671	13	-	-	HYPH
cord-310847-63gh2tg4	671	14	rich	rich	JJ
cord-310847-63gh2tg4	671	15	region	region	NN
cord-310847-63gh2tg4	671	16	(	(	-LRB-
cord-310847-63gh2tg4	671	17	residues	residue	NNS
cord-310847-63gh2tg4	671	18	170	170	CD
cord-310847-63gh2tg4	671	19	-	-	HYPH
cord-310847-63gh2tg4	671	20	239	239	CD
cord-310847-63gh2tg4	671	21	)	)	-RRB-
cord-310847-63gh2tg4	671	22	,	,	,
cord-310847-63gh2tg4	671	23	~43	~43	NFP
cord-310847-63gh2tg4	671	24	%	%	NN
cord-310847-63gh2tg4	671	25	of	of	IN
cord-310847-63gh2tg4	671	26	which	which	WDT
cord-310847-63gh2tg4	671	27	are	be	VBP
cord-310847-63gh2tg4	671	28	glutamic	glutamic	JJ
cord-310847-63gh2tg4	671	29	acid	acid	NN
cord-310847-63gh2tg4	671	30	residues	residue	NNS
cord-310847-63gh2tg4	671	31	.	.	.
cord-310847-63gh2tg4	672	1	In	in	IN
cord-310847-63gh2tg4	672	2	addition	addition	NN
cord-310847-63gh2tg4	672	3	to	to	IN
cord-310847-63gh2tg4	672	4	SH3BGR	sh3bgr	NN
cord-310847-63gh2tg4	672	5	,	,	,
cord-310847-63gh2tg4	672	6	several	several	JJ
cord-310847-63gh2tg4	672	7	other	other	JJ
cord-310847-63gh2tg4	672	8	members	member	NNS
cord-310847-63gh2tg4	672	9	of	of	IN
cord-310847-63gh2tg4	672	10	the	the	DT
cord-310847-63gh2tg4	672	11	SH3BGR	SH3BGR	NNP
cord-310847-63gh2tg4	672	12	family	family	NN
cord-310847-63gh2tg4	672	13	were	be	VBD
cord-310847-63gh2tg4	672	14	found	find	VBN
cord-310847-63gh2tg4	672	15	in	in	IN
cord-310847-63gh2tg4	672	16	humans	human	NNS
cord-310847-63gh2tg4	672	17	.	.	.
cord-310847-63gh2tg4	673	1	These	these	DT
cord-310847-63gh2tg4	673	2	are	be	VBP
cord-310847-63gh2tg4	673	3	the	the	DT
cord-310847-63gh2tg4	673	4	so	so	RB
cord-310847-63gh2tg4	673	5	-	-	HYPH
cord-310847-63gh2tg4	673	6	called	call	VBN
cord-310847-63gh2tg4	673	7	SH3BGR	sh3bgr	NN
cord-310847-63gh2tg4	673	8	-	-	HYPH
cord-310847-63gh2tg4	673	9	like	like	JJ
cord-310847-63gh2tg4	673	10	proteins	protein	NNS
cord-310847-63gh2tg4	673	11	,	,	,
cord-310847-63gh2tg4	673	12	such	such	JJ
cord-310847-63gh2tg4	673	13	as	as	IN
cord-310847-63gh2tg4	673	14	SH3BGRL	SH3BGRL	NNP
cord-310847-63gh2tg4	673	15	(	(	-LRB-
cord-310847-63gh2tg4	673	16	114	114	CD
cord-310847-63gh2tg4	673	17	residues	residue	NNS
cord-310847-63gh2tg4	673	18	,	,	,
cord-310847-63gh2tg4	673	19	12	12	CD
cord-310847-63gh2tg4	673	20	glutamic	glutamic	NN
cord-310847-63gh2tg4	673	21	acids	acid	NNS
cord-310847-63gh2tg4	673	22	)	)	-RRB-
cord-310847-63gh2tg4	673	23	,	,	,
cord-310847-63gh2tg4	674	1	SH3BGRL2	sh3bgrl2	CD
cord-310847-63gh2tg4	675	1	(	(	-LRB-
cord-310847-63gh2tg4	675	2	107	107	CD
cord-310847-63gh2tg4	675	3	residues	residue	NNS
cord-310847-63gh2tg4	675	4	,	,	,
cord-310847-63gh2tg4	675	5	10	10	CD
cord-310847-63gh2tg4	675	6	glutamic	glutamic	NN
cord-310847-63gh2tg4	675	7	acids	acid	NNS
cord-310847-63gh2tg4	675	8	)	)	-RRB-
cord-310847-63gh2tg4	675	9	and	and	CC
cord-310847-63gh2tg4	675	10	SH3BGRL3	sh3bgrl3	CD
cord-310847-63gh2tg4	675	11	(	(	-LRB-
cord-310847-63gh2tg4	675	12	93	93	CD
cord-310847-63gh2tg4	675	13	residues	residue	NNS
cord-310847-63gh2tg4	675	14	,	,	,
cord-310847-63gh2tg4	675	15	7	7	CD
cord-310847-63gh2tg4	675	16	glutamic	glutamic	JJ
cord-310847-63gh2tg4	675	17	acids	acid	NNS
cord-310847-63gh2tg4	675	18	)	)	-RRB-
cord-310847-63gh2tg4	675	19	encoded	encode	VBN
cord-310847-63gh2tg4	675	20	by	by	IN
cord-310847-63gh2tg4	675	21	chromosomes	chromosome	NNS
cord-310847-63gh2tg4	676	1	Xq13.3	Xq13.3	NNP
cord-310847-63gh2tg4	676	2	6q13	6q13	CD
cord-310847-63gh2tg4	676	3	-	-	SYM
cord-310847-63gh2tg4	676	4	15	15	CD
cord-310847-63gh2tg4	676	5	,	,	,
cord-310847-63gh2tg4	676	6	and	and	CC
cord-310847-63gh2tg4	676	7	1p34.3	1p34.3	CD
cord-310847-63gh2tg4	676	8	-	-	SYM
cord-310847-63gh2tg4	676	9	35	35	CD
cord-310847-63gh2tg4	676	10	,	,	,
cord-310847-63gh2tg4	676	11	respectively	respectively	RB
cord-310847-63gh2tg4	676	12	.	.	.
cord-310847-63gh2tg4	677	1	226	226	CD
cord-310847-63gh2tg4	678	1	It	-PRON-	PRP
cord-310847-63gh2tg4	678	2	was	be	VBD
cord-310847-63gh2tg4	678	3	shown	show	VBN
cord-310847-63gh2tg4	678	4	that	that	IN
cord-310847-63gh2tg4	678	5	the	the	DT
cord-310847-63gh2tg4	678	6	SH3	SH3	NNP
cord-310847-63gh2tg4	678	7	domainbinding	domainbinde	VBG
cord-310847-63gh2tg4	678	8	glutamic	glutamic	NN
cord-310847-63gh2tg4	678	9	acid	acid	NN
cord-310847-63gh2tg4	678	10	-	-	HYPH
cord-310847-63gh2tg4	678	11	rich	rich	JJ
cord-310847-63gh2tg4	678	12	-	-	HYPH
cord-310847-63gh2tg4	678	13	like	like	JJ
cord-310847-63gh2tg4	678	14	protein	protein	NN
cord-310847-63gh2tg4	678	15	3	3	CD
cord-310847-63gh2tg4	678	16	is	be	VBZ
cord-310847-63gh2tg4	678	17	upregulated	upregulate	VBN
cord-310847-63gh2tg4	678	18	in	in	IN
cord-310847-63gh2tg4	678	19	glioblastoma	glioblastoma	NN
cord-310847-63gh2tg4	678	20	.	.	.
cord-310847-63gh2tg4	679	1	227	227	CD
cord-310847-63gh2tg4	680	1	Also	also	RB
cord-310847-63gh2tg4	680	2	,	,	,
cord-310847-63gh2tg4	680	3	this	this	DT
cord-310847-63gh2tg4	680	4	protein	protein	NN
cord-310847-63gh2tg4	680	5	was	be	VBD
cord-310847-63gh2tg4	680	6	noticeably	noticeably	RB
cord-310847-63gh2tg4	680	7	downregulated	downregulate	VBN
cord-310847-63gh2tg4	680	8	in	in	IN
cord-310847-63gh2tg4	680	9	nucleotide	nucleotide	RB
cord-310847-63gh2tg4	680	10	-	-	HYPH
cord-310847-63gh2tg4	680	11	gated	gate	VBN
cord-310847-63gh2tg4	680	12	(	(	-LRB-
cord-310847-63gh2tg4	680	13	CNG	CNG	NNP
cord-310847-63gh2tg4	680	14	)	)	-RRB-
cord-310847-63gh2tg4	680	15	cation	cation	NNP
cord-310847-63gh2tg4	680	16	channel	channel	NN
cord-310847-63gh2tg4	680	17	of	of	IN
cord-310847-63gh2tg4	680	18	rod	rod	NN
cord-310847-63gh2tg4	680	19	photoreceptors	photoreceptor	NNS
cord-310847-63gh2tg4	680	20	is	be	VBZ
cord-310847-63gh2tg4	680	21	a	a	DT
cord-310847-63gh2tg4	680	22	heterotetramer	heterotetramer	NN
cord-310847-63gh2tg4	680	23	consisting	consisting	NN
cord-310847-63gh2tg4	680	24	of	of	IN
cord-310847-63gh2tg4	680	25	homologous	homologous	JJ
cord-310847-63gh2tg4	680	26	subunits	subunit	NNS
cord-310847-63gh2tg4	680	27	,	,	,
cord-310847-63gh2tg4	680	28	α	α	NN
cord-310847-63gh2tg4	680	29	and	and	CC
cord-310847-63gh2tg4	680	30	β	β	NN
cord-310847-63gh2tg4	680	31	(	(	-LRB-
cord-310847-63gh2tg4	680	32	also	also	RB
cord-310847-63gh2tg4	680	33	known	know	VBN
cord-310847-63gh2tg4	680	34	as	as	IN
cord-310847-63gh2tg4	680	35	CNGA1	CNGA1	NNP
cord-310847-63gh2tg4	680	36	and	and	CC
cord-310847-63gh2tg4	680	37	CNGB1a	CNGB1a	NNP
cord-310847-63gh2tg4	680	38	)	)	-RRB-
cord-310847-63gh2tg4	680	39	.	.	.
cord-310847-63gh2tg4	681	1	CNGA1	CNGA1	NNP
cord-310847-63gh2tg4	681	2	is	be	VBZ
cord-310847-63gh2tg4	681	3	known	know	VBN
cord-310847-63gh2tg4	681	4	to	to	TO
cord-310847-63gh2tg4	681	5	be	be	VB
cord-310847-63gh2tg4	681	6	indispensable	indispensable	JJ
cord-310847-63gh2tg4	681	7	for	for	IN
cord-310847-63gh2tg4	681	8	channel	channel	NN
cord-310847-63gh2tg4	681	9	activation	activation	NN
cord-310847-63gh2tg4	681	10	,	,	,
cord-310847-63gh2tg4	681	11	whereas	whereas	IN
cord-310847-63gh2tg4	681	12	CNGB1a	cngb1a	NN
cord-310847-63gh2tg4	681	13	plays	play	VBZ
cord-310847-63gh2tg4	681	14	mostly	mostly	RB
cord-310847-63gh2tg4	681	15	regulatory	regulatory	JJ
cord-310847-63gh2tg4	681	16	structural	structural	JJ
cord-310847-63gh2tg4	681	17	roles	role	NNS
cord-310847-63gh2tg4	681	18	.	.	.
cord-310847-63gh2tg4	682	1	205	205	CD
cord-310847-63gh2tg4	683	1	In	in	IN
cord-310847-63gh2tg4	683	2	fact	fact	NN
cord-310847-63gh2tg4	683	3	,	,	,
cord-310847-63gh2tg4	683	4	the	the	DT
cord-310847-63gh2tg4	683	5	N	n	CD
cord-310847-63gh2tg4	683	6	-	-	HYPH
cord-310847-63gh2tg4	683	7	terminal	terminal	JJ
cord-310847-63gh2tg4	683	8	glutamic	glutamic	NN
cord-310847-63gh2tg4	683	9	acid	acid	NN
cord-310847-63gh2tg4	683	10	-	-	HYPH
cord-310847-63gh2tg4	683	11	rich	rich	JJ
cord-310847-63gh2tg4	683	12	protein	protein	NN
cord-310847-63gh2tg4	683	13	(	(	-LRB-
cord-310847-63gh2tg4	683	14	GARP	GARP	NNP
cord-310847-63gh2tg4	683	15	)	)	-RRB-
cord-310847-63gh2tg4	683	16	domain	domain	NN
cord-310847-63gh2tg4	683	17	of	of	IN
cord-310847-63gh2tg4	683	18	CNGB1a	cngb1a	NN
cord-310847-63gh2tg4	683	19	and	and	CC
cord-310847-63gh2tg4	683	20	the	the	DT
cord-310847-63gh2tg4	683	21	soluble	soluble	JJ
cord-310847-63gh2tg4	683	22	GARP2	garp2	NN
cord-310847-63gh2tg4	683	23	were	be	VBD
cord-310847-63gh2tg4	683	24	shown	show	VBN
cord-310847-63gh2tg4	683	25	to	to	TO
cord-310847-63gh2tg4	683	26	decrease	decrease	VB
cord-310847-63gh2tg4	683	27	the	the	DT
cord-310847-63gh2tg4	683	28	opening	open	VBG
cord-310847-63gh2tg4	683	29	probability	probability	NN
cord-310847-63gh2tg4	683	30	of	of	IN
cord-310847-63gh2tg4	683	31	the	the	DT
cord-310847-63gh2tg4	683	32	CNG	CNG	NNP
cord-310847-63gh2tg4	683	33	channel	channel	NN
cord-310847-63gh2tg4	683	34	and	and	CC
cord-310847-63gh2tg4	683	35	therefore	therefore	RB
cord-310847-63gh2tg4	683	36	these	these	DT
cord-310847-63gh2tg4	683	37	GARPs	garp	NNS
cord-310847-63gh2tg4	683	38	serve	serve	VBP
cord-310847-63gh2tg4	683	39	as	as	IN
cord-310847-63gh2tg4	683	40	important	important	JJ
cord-310847-63gh2tg4	683	41	autoinhibitors	autoinhibitor	NNS
cord-310847-63gh2tg4	683	42	or	or	CC
cord-310847-63gh2tg4	683	43	molecular	molecular	JJ
cord-310847-63gh2tg4	683	44	gate	gate	NN
cord-310847-63gh2tg4	683	45	keepers	keeper	NNS
cord-310847-63gh2tg4	683	46	that	that	WDT
cord-310847-63gh2tg4	683	47	control	control	VBP
cord-310847-63gh2tg4	683	48	the	the	DT
cord-310847-63gh2tg4	683	49	activation	activation	NN
cord-310847-63gh2tg4	683	50	of	of	IN
cord-310847-63gh2tg4	683	51	heteromeric	heteromeric	NNP
cord-310847-63gh2tg4	683	52	rod	rod	NNP
cord-310847-63gh2tg4	683	53	CNG	CNG	NNP
cord-310847-63gh2tg4	683	54	channels	channel	NNS
cord-310847-63gh2tg4	683	55	.	.	.
cord-310847-63gh2tg4	684	1	205	205	CD
cord-310847-63gh2tg4	685	1	Furthermore	furthermore	RB
cord-310847-63gh2tg4	685	2	,	,	,
cord-310847-63gh2tg4	685	3	CNGB1	CNGB1	NNP
cord-310847-63gh2tg4	685	4	and	and	CC
cord-310847-63gh2tg4	685	5	GARP2	GARP2	NNP
cord-310847-63gh2tg4	685	6	,	,	,
cord-310847-63gh2tg4	685	7	in	in	IN
cord-310847-63gh2tg4	685	8	concert	concert	NN
cord-310847-63gh2tg4	685	9	with	with	IN
cord-310847-63gh2tg4	685	10	a	a	DT
cord-310847-63gh2tg4	685	11	retinal	retinal	JJ
cord-310847-63gh2tg4	685	12	tetraspanin	tetraspanin	NNS
cord-310847-63gh2tg4	685	13	(	(	-LRB-
cord-310847-63gh2tg4	685	14	peripherin-2	peripherin-2	NNP
cord-310847-63gh2tg4	685	15	or	or	CC
cord-310847-63gh2tg4	685	16	peripherin	peripherin	NNP
cord-310847-63gh2tg4	685	17	RDS	RDS	NNP
cord-310847-63gh2tg4	685	18	)	)	-RRB-
cord-310847-63gh2tg4	685	19	,	,	,
cord-310847-63gh2tg4	685	20	were	be	VBD
cord-310847-63gh2tg4	685	21	shown	show	VBN
cord-310847-63gh2tg4	685	22	to	to	TO
cord-310847-63gh2tg4	685	23	contribute	contribute	VB
cord-310847-63gh2tg4	685	24	to	to	IN
cord-310847-63gh2tg4	685	25	the	the	DT
cord-310847-63gh2tg4	685	26	organization	organization	NN
cord-310847-63gh2tg4	685	27	of	of	IN
cord-310847-63gh2tg4	685	28	the	the	DT
cord-310847-63gh2tg4	685	29	specific	specific	JJ
cord-310847-63gh2tg4	685	30	organelle	organelle	NN
cord-310847-63gh2tg4	685	31	,	,	,
cord-310847-63gh2tg4	685	32	outer	outer	JJ
cord-310847-63gh2tg4	685	33	segment	segment	NN
cord-310847-63gh2tg4	685	34	(	(	-LRB-
cord-310847-63gh2tg4	685	35	OS	OS	NNP
cord-310847-63gh2tg4	685	36	)	)	-RRB-
cord-310847-63gh2tg4	685	37	,	,	,
cord-310847-63gh2tg4	685	38	which	which	WDT
cord-310847-63gh2tg4	685	39	possesses	possess	VBZ
cord-310847-63gh2tg4	685	40	a	a	DT
cord-310847-63gh2tg4	685	41	characteristic	characteristic	JJ
cord-310847-63gh2tg4	685	42	membranous	membranous	JJ
cord-310847-63gh2tg4	685	43	"	"	''
cord-310847-63gh2tg4	685	44	stacked	stack	VBN
cord-310847-63gh2tg4	685	45	pancake	pancake	NN
cord-310847-63gh2tg4	685	46	"	"	''
cord-310847-63gh2tg4	685	47	architecture	architecture	NN
cord-310847-63gh2tg4	685	48	that	that	WDT
cord-310847-63gh2tg4	685	49	has	have	VBZ
cord-310847-63gh2tg4	685	50	to	to	TO
cord-310847-63gh2tg4	685	51	be	be	VB
cord-310847-63gh2tg4	685	52	partially	partially	RB
cord-310847-63gh2tg4	685	53	renewed	renew	VBN
cord-310847-63gh2tg4	685	54	daily	daily	RB
cord-310847-63gh2tg4	685	55	to	to	TO
cord-310847-63gh2tg4	685	56	maintain	maintain	VB
cord-310847-63gh2tg4	685	57	cell	cell	NN
cord-310847-63gh2tg4	685	58	function	function	NN
cord-310847-63gh2tg4	685	59	and	and	CC
cord-310847-63gh2tg4	685	60	viability	viability	NN
cord-310847-63gh2tg4	685	61	.	.	.
cord-310847-63gh2tg4	686	1	206	206	CD
cord-310847-63gh2tg4	687	1	In	in	IN
cord-310847-63gh2tg4	687	2	fact	fact	NN
cord-310847-63gh2tg4	687	3	,	,	,
cord-310847-63gh2tg4	687	4	a	a	DT
cord-310847-63gh2tg4	687	5	mouse	mouse	NN
cord-310847-63gh2tg4	687	6	knockout	knockout	NN
cord-310847-63gh2tg4	687	7	of	of	IN
cord-310847-63gh2tg4	687	8	CNGB1	CNGB1	NNP
cord-310847-63gh2tg4	687	9	and	and	CC
cord-310847-63gh2tg4	687	10	GARP2	GARP2	NNP
cord-310847-63gh2tg4	687	11	attenuated	attenuated	JJ
cord-310847-63gh2tg4	687	12	rod	rod	NN
cord-310847-63gh2tg4	687	13	function	function	NN
cord-310847-63gh2tg4	687	14	and	and	CC
cord-310847-63gh2tg4	687	15	caused	cause	VBN
cord-310847-63gh2tg4	687	16	structural	structural	JJ
cord-310847-63gh2tg4	687	17	alterations	alteration	NNS
cord-310847-63gh2tg4	687	18	and	and	CC
cord-310847-63gh2tg4	687	19	slowly	slowly	RB
cord-310847-63gh2tg4	687	20	progressive	progressive	JJ
cord-310847-63gh2tg4	687	21	retinal	retinal	JJ
cord-310847-63gh2tg4	687	22	degeneration	degeneration	NN
cord-310847-63gh2tg4	687	23	.	.	.
cord-310847-63gh2tg4	688	1	207	207	CD
cord-310847-63gh2tg4	688	2	Bovine	bovine	JJ
cord-310847-63gh2tg4	688	3	GARP	garp	NN
cord-310847-63gh2tg4	688	4	(	(	-LRB-
cord-310847-63gh2tg4	688	5	or	or	CC
cord-310847-63gh2tg4	688	6	CNGB1	CNGB1	NNP
cord-310847-63gh2tg4	688	7	)	)	-RRB-
cord-310847-63gh2tg4	688	8	is	be	VBZ
cord-310847-63gh2tg4	688	9	a	a	DT
cord-310847-63gh2tg4	688	10	1,394	1,394	CD
cord-310847-63gh2tg4	688	11	residues	residue	NNS
cord-310847-63gh2tg4	688	12	-	-	HYPH
cord-310847-63gh2tg4	688	13	long	long	JJ
cord-310847-63gh2tg4	688	14	transmembrane	transmembrane	NN
cord-310847-63gh2tg4	688	15	protein	protein	NN
cord-310847-63gh2tg4	688	16	which	which	WDT
cord-310847-63gh2tg4	688	17	plays	play	VBZ
cord-310847-63gh2tg4	688	18	important	important	JJ
cord-310847-63gh2tg4	688	19	roles	role	NNS
cord-310847-63gh2tg4	688	20	in	in	IN
cord-310847-63gh2tg4	688	21	both	both	CC
cord-310847-63gh2tg4	688	22	visual	visual	JJ
cord-310847-63gh2tg4	688	23	and	and	CC
cord-310847-63gh2tg4	688	24	olfactory	olfactory	JJ
cord-310847-63gh2tg4	688	25	signal	signal	NN
cord-310847-63gh2tg4	688	26	transduction	transduction	NN
cord-310847-63gh2tg4	688	27	.	.	.
cord-310847-63gh2tg4	689	1	CNGB1	CNGB1	NNP
cord-310847-63gh2tg4	689	2	has	have	VBZ
cord-310847-63gh2tg4	689	3	209	209	CD
cord-310847-63gh2tg4	689	4	glutamic	glutamic	JJ
cord-310847-63gh2tg4	689	5	acids	acid	NNS
cord-310847-63gh2tg4	689	6	.	.	.
cord-310847-63gh2tg4	690	1	GARP1	GARP1	NNP
cord-310847-63gh2tg4	690	2	is	be	VBZ
cord-310847-63gh2tg4	690	3	a	a	DT
cord-310847-63gh2tg4	690	4	590-residues	590-residues	CD
cord-310847-63gh2tg4	690	5	-	-	HYPH
cord-310847-63gh2tg4	690	6	long	long	JJ
cord-310847-63gh2tg4	690	7	CNGB1	CNGB1	HYPH
cord-310847-63gh2tg4	690	8	splice	splice	NN
cord-310847-63gh2tg4	690	9	variant	variant	NN
cord-310847-63gh2tg4	690	10	that	that	WDT
cord-310847-63gh2tg4	690	11	possesses	possess	VBZ
cord-310847-63gh2tg4	690	12	141	141	CD
cord-310847-63gh2tg4	690	13	glutamic	glutamic	NN
cord-310847-63gh2tg4	690	14	acids	acid	NNS
cord-310847-63gh2tg4	690	15	.	.	.
cord-310847-63gh2tg4	691	1	GARP2	GARP2	NNP
cord-310847-63gh2tg4	691	2	is	be	VBZ
cord-310847-63gh2tg4	691	3	another	another	DT
cord-310847-63gh2tg4	691	4	CNGB1	CNGB1	NNP
cord-310847-63gh2tg4	691	5	splice	splice	NN
cord-310847-63gh2tg4	691	6	variant	variant	NN
cord-310847-63gh2tg4	691	7	that	that	WDT
cord-310847-63gh2tg4	691	8	has	have	VBZ
cord-310847-63gh2tg4	691	9	299	299	CD
cord-310847-63gh2tg4	691	10	residues	residue	NNS
cord-310847-63gh2tg4	691	11	38	38	CD
cord-310847-63gh2tg4	691	12	of	of	IN
cord-310847-63gh2tg4	691	13	which	which	WDT
cord-310847-63gh2tg4	691	14	are	be	VBP
cord-310847-63gh2tg4	691	15	glutamic	glutamic	JJ
cord-310847-63gh2tg4	691	16	acids	acid	NNS
cord-310847-63gh2tg4	691	17	.	.	.
cord-310847-63gh2tg4	692	1	Native	native	JJ
cord-310847-63gh2tg4	692	2	GARP1	GARP1	NNS
cord-310847-63gh2tg4	692	3	and	and	CC
cord-310847-63gh2tg4	692	4	GARP2	GARP2	NNP
cord-310847-63gh2tg4	692	5	purified	purify	VBN
cord-310847-63gh2tg4	692	6	from	from	IN
cord-310847-63gh2tg4	692	7	bovine	bovine	JJ
cord-310847-63gh2tg4	692	8	rod	rod	NN
cord-310847-63gh2tg4	692	9	photoreceptors	photoreceptor	NNS
cord-310847-63gh2tg4	692	10	were	be	VBD
cord-310847-63gh2tg4	692	11	shown	show	VBN
cord-310847-63gh2tg4	692	12	to	to	TO
cord-310847-63gh2tg4	692	13	be	be	VB
cord-310847-63gh2tg4	692	14	typical	typical	JJ
cord-310847-63gh2tg4	692	15	IDPs	idp	NNS
cord-310847-63gh2tg4	692	16	.	.	.
cord-310847-63gh2tg4	693	1	208	208	CD
cord-310847-63gh2tg4	693	2	MGARP	MGARP	NNP
cord-310847-63gh2tg4	693	3	.	.	.
cord-310847-63gh2tg4	694	1	Mitochondria	mitochondria	NN
cord-310847-63gh2tg4	694	2	-	-	HYPH
cord-310847-63gh2tg4	694	3	localized	localize	VBN
cord-310847-63gh2tg4	694	4	glutamic	glutamic	NN
cord-310847-63gh2tg4	694	5	acid	acid	NN
cord-310847-63gh2tg4	694	6	-	-	HYPH
cord-310847-63gh2tg4	694	7	rich	rich	JJ
cord-310847-63gh2tg4	694	8	protein	protein	NN
cord-310847-63gh2tg4	694	9	[	[	-LRB-
cord-310847-63gh2tg4	694	10	MGARP	MGARP	NNP
cord-310847-63gh2tg4	694	11	,	,	,
cord-310847-63gh2tg4	694	12	which	which	WDT
cord-310847-63gh2tg4	694	13	is	be	VBZ
cord-310847-63gh2tg4	694	14	also	also	RB
cord-310847-63gh2tg4	694	15	known	know	VBN
cord-310847-63gh2tg4	694	16	as	as	IN
cord-310847-63gh2tg4	694	17	ovary	ovary	NN
cord-310847-63gh2tg4	694	18	-	-	HYPH
cord-310847-63gh2tg4	694	19	specific	specific	JJ
cord-310847-63gh2tg4	694	20	acidic	acidic	JJ
cord-310847-63gh2tg4	694	21	protein	protein	NN
cord-310847-63gh2tg4	694	22	(	(	-LRB-
cord-310847-63gh2tg4	694	23	OSAP	OSAP	NNP
cord-310847-63gh2tg4	694	24	)	)	-RRB-
cord-310847-63gh2tg4	694	25	,	,	,
cord-310847-63gh2tg4	694	26	corneal	corneal	JJ
cord-310847-63gh2tg4	694	27	endothelium	endothelium	NN
cord-310847-63gh2tg4	694	28	-	-	HYPH
cord-310847-63gh2tg4	694	29	specific	specific	JJ
cord-310847-63gh2tg4	694	30	protein	protein	NN
cord-310847-63gh2tg4	694	31	1	1	CD
cord-310847-63gh2tg4	694	32	(	(	-LRB-
cord-310847-63gh2tg4	694	33	CESP-1	CESP-1	NNP
cord-310847-63gh2tg4	694	34	)	)	-RRB-
cord-310847-63gh2tg4	694	35	and	and	CC
cord-310847-63gh2tg4	694	36	hypoxia	hypoxia	NN
cord-310847-63gh2tg4	694	37	upregulated	upregulate	VBN
cord-310847-63gh2tg4	694	38	mitochondrial	mitochondrial	JJ
cord-310847-63gh2tg4	694	39	movement	movement	NN
cord-310847-63gh2tg4	694	40	regulator	regulator	NN
cord-310847-63gh2tg4	694	41	protein	protein	NN
cord-310847-63gh2tg4	694	42	(	(	-LRB-
cord-310847-63gh2tg4	694	43	HUMMR	HUMMR	NNP
cord-310847-63gh2tg4	694	44	)	)	-RRB-
cord-310847-63gh2tg4	694	45	]	]	-RRB-
cord-310847-63gh2tg4	694	46	is	be	VBZ
cord-310847-63gh2tg4	694	47	one	one	CD
cord-310847-63gh2tg4	694	48	of	of	IN
cord-310847-63gh2tg4	694	49	the	the	DT
cord-310847-63gh2tg4	694	50	highly	highly	RB
cord-310847-63gh2tg4	694	51	expressed	express	VBN
cord-310847-63gh2tg4	694	52	proteins	protein	NNS
cord-310847-63gh2tg4	694	53	in	in	IN
cord-310847-63gh2tg4	694	54	retina	retina	NN
cord-310847-63gh2tg4	694	55	.	.	.
cord-310847-63gh2tg4	695	1	209	209	CD
cord-310847-63gh2tg4	695	2	MGARP	MGARP	NNP
cord-310847-63gh2tg4	695	3	is	be	VBZ
cord-310847-63gh2tg4	695	4	highly	highly	RB
cord-310847-63gh2tg4	695	5	enriched	enrich	VBN
cord-310847-63gh2tg4	695	6	in	in	IN
cord-310847-63gh2tg4	695	7	steroidogenic	steroidogenic	JJ
cord-310847-63gh2tg4	695	8	tissues	tissue	NNS
cord-310847-63gh2tg4	695	9	and	and	CC
cord-310847-63gh2tg4	695	10	the	the	DT
cord-310847-63gh2tg4	695	11	visual	visual	JJ
cord-310847-63gh2tg4	695	12	system	system	NN
cord-310847-63gh2tg4	695	13	,	,	,
cord-310847-63gh2tg4	695	14	and	and	CC
cord-310847-63gh2tg4	695	15	early	early	RB
cord-310847-63gh2tg4	695	16	in	in	IN
cord-310847-63gh2tg4	695	17	development	development	NN
cord-310847-63gh2tg4	695	18	,	,	,
cord-310847-63gh2tg4	695	19	this	this	DT
cord-310847-63gh2tg4	695	20	protein	protein	NN
cord-310847-63gh2tg4	695	21	is	be	VBZ
cord-310847-63gh2tg4	695	22	mainly	mainly	RB
cord-310847-63gh2tg4	695	23	detected	detect	VBN
cord-310847-63gh2tg4	695	24	in	in	IN
cord-310847-63gh2tg4	695	25	the	the	DT
cord-310847-63gh2tg4	695	26	retina	retina	JJ
cord-310847-63gh2tg4	695	27	and	and	CC
cord-310847-63gh2tg4	695	28	adrenal	adrenal	JJ
cord-310847-63gh2tg4	695	29	gland	gland	NN
cord-310847-63gh2tg4	695	30	.	.	.
cord-310847-63gh2tg4	696	1	210	210	CD
cord-310847-63gh2tg4	697	1	During	during	IN
cord-310847-63gh2tg4	697	2	the	the	DT
cord-310847-63gh2tg4	697	3	estrous	estrous	JJ
cord-310847-63gh2tg4	697	4	cycle	cycle	NN
cord-310847-63gh2tg4	697	5	,	,	,
cord-310847-63gh2tg4	697	6	MGARP	MGARP	NNP
cord-310847-63gh2tg4	697	7	levels	level	NNS
cord-310847-63gh2tg4	697	8	correlate	correlate	VBP
cord-310847-63gh2tg4	697	9	with	with	IN
cord-310847-63gh2tg4	697	10	estrogen	estrogen	NN
cord-310847-63gh2tg4	697	11	levels	level	NNS
cord-310847-63gh2tg4	697	12	in	in	IN
cord-310847-63gh2tg4	697	13	the	the	DT
cord-310847-63gh2tg4	697	14	ovaries	ovary	NNS
cord-310847-63gh2tg4	697	15	.	.	.
cord-310847-63gh2tg4	698	1	Furthermore	furthermore	RB
cord-310847-63gh2tg4	698	2	,	,	,
cord-310847-63gh2tg4	698	3	the	the	DT
cord-310847-63gh2tg4	698	4	expression	expression	NN
cord-310847-63gh2tg4	698	5	of	of	IN
cord-310847-63gh2tg4	698	6	MGARP	MGARP	NNP
cord-310847-63gh2tg4	698	7	is	be	VBZ
cord-310847-63gh2tg4	698	8	regulated	regulate	VBN
cord-310847-63gh2tg4	698	9	by	by	IN
cord-310847-63gh2tg4	698	10	estrogen	estrogen	NN
cord-310847-63gh2tg4	698	11	in	in	IN
cord-310847-63gh2tg4	698	12	a	a	DT
cord-310847-63gh2tg4	698	13	tissue	tissue	NN
cord-310847-63gh2tg4	698	14	-	-	HYPH
cord-310847-63gh2tg4	698	15	specific	specific	JJ
cord-310847-63gh2tg4	698	16	manner	manner	NN
cord-310847-63gh2tg4	698	17	and	and	CC
cord-310847-63gh2tg4	698	18	through	through	IN
cord-310847-63gh2tg4	698	19	a	a	DT
cord-310847-63gh2tg4	698	20	feedback	feedback	NN
cord-310847-63gh2tg4	698	21	regulatory	regulatory	JJ
cord-310847-63gh2tg4	698	22	mechanism	mechanism	NN
cord-310847-63gh2tg4	698	23	.	.	.
cord-310847-63gh2tg4	699	1	210	210	CD
cord-310847-63gh2tg4	700	1	As	as	IN
cord-310847-63gh2tg4	700	2	it	-PRON-	PRP
cord-310847-63gh2tg4	700	3	follows	follow	VBZ
cord-310847-63gh2tg4	700	4	from	from	IN
cord-310847-63gh2tg4	700	5	a	a	DT
cord-310847-63gh2tg4	700	6	long	long	JJ
cord-310847-63gh2tg4	700	7	list	list	NN
cord-310847-63gh2tg4	700	8	of	of	IN
cord-310847-63gh2tg4	700	9	names	name	NNS
cord-310847-63gh2tg4	700	10	,	,	,
cord-310847-63gh2tg4	700	11	this	this	DT
cord-310847-63gh2tg4	700	12	protein	protein	NN
cord-310847-63gh2tg4	700	13	has	have	VBZ
cord-310847-63gh2tg4	700	14	numerous	numerous	JJ
cord-310847-63gh2tg4	700	15	important	important	JJ
cord-310847-63gh2tg4	700	16	functions	function	NNS
cord-310847-63gh2tg4	700	17	.	.	.
cord-310847-63gh2tg4	701	1	In	in	IN
cord-310847-63gh2tg4	701	2	fact	fact	NN
cord-310847-63gh2tg4	701	3	,	,	,
cord-310847-63gh2tg4	701	4	among	among	IN
cord-310847-63gh2tg4	701	5	functions	function	NNS
cord-310847-63gh2tg4	701	6	listed	list	VBN
cord-310847-63gh2tg4	701	7	for	for	IN
cord-310847-63gh2tg4	701	8	this	this	DT
cord-310847-63gh2tg4	701	9	protein	protein	NN
cord-310847-63gh2tg4	701	10	in	in	IN
cord-310847-63gh2tg4	701	11	the	the	DT
cord-310847-63gh2tg4	701	12	UniProt	UniProt	NNP
cord-310847-63gh2tg4	701	13	are	be	VBP
cord-310847-63gh2tg4	701	14	(	(	-LRB-
cord-310847-63gh2tg4	701	15	1	1	CD
cord-310847-63gh2tg4	701	16	)	)	-RRB-
cord-310847-63gh2tg4	701	17	plays	play	VBZ
cord-310847-63gh2tg4	701	18	a	a	DT
cord-310847-63gh2tg4	701	19	role	role	NN
cord-310847-63gh2tg4	701	20	in	in	IN
cord-310847-63gh2tg4	701	21	the	the	DT
cord-310847-63gh2tg4	701	22	trafficking	trafficking	NN
cord-310847-63gh2tg4	701	23	of	of	IN
cord-310847-63gh2tg4	701	24	mitochondria	mitochondrion	NNS
cord-310847-63gh2tg4	701	25	along	along	IN
cord-310847-63gh2tg4	701	26	microtubules	microtubule	NNS
cord-310847-63gh2tg4	701	27	,	,	,
cord-310847-63gh2tg4	701	28	(	(	-LRB-
cord-310847-63gh2tg4	701	29	2	2	LS
cord-310847-63gh2tg4	701	30	)	)	-RRB-
cord-310847-63gh2tg4	701	31	regulates	regulate	VBZ
cord-310847-63gh2tg4	701	32	the	the	DT
cord-310847-63gh2tg4	701	33	kinesin	kinesin	NN
cord-310847-63gh2tg4	701	34	-	-	HYPH
cord-310847-63gh2tg4	701	35	mediated	mediate	VBN
cord-310847-63gh2tg4	701	36	axonal	axonal	JJ
cord-310847-63gh2tg4	701	37	transport	transport	NN
cord-310847-63gh2tg4	701	38	of	of	IN
cord-310847-63gh2tg4	701	39	mitochondria	mitochondrion	NNS
cord-310847-63gh2tg4	701	40	to	to	IN
cord-310847-63gh2tg4	701	41	nerve	nerve	NN
cord-310847-63gh2tg4	701	42	terminals	terminal	NNS
cord-310847-63gh2tg4	701	43	along	along	IN
cord-310847-63gh2tg4	701	44	microtubules	microtubule	NNS
cord-310847-63gh2tg4	701	45	during	during	IN
cord-310847-63gh2tg4	701	46	hypoxia	hypoxia	NN
cord-310847-63gh2tg4	701	47	,	,	,
cord-310847-63gh2tg4	701	48	(	(	-LRB-
cord-310847-63gh2tg4	701	49	3	3	LS
cord-310847-63gh2tg4	701	50	)	)	-RRB-
cord-310847-63gh2tg4	701	51	participates	participate	VBZ
cord-310847-63gh2tg4	701	52	in	in	IN
cord-310847-63gh2tg4	701	53	the	the	DT
cord-310847-63gh2tg4	701	54	translocation	translocation	NN
cord-310847-63gh2tg4	701	55	of	of	IN
cord-310847-63gh2tg4	701	56	TRAK2	TRAK2	NNS
cord-310847-63gh2tg4	701	57	/	/	SYM
cord-310847-63gh2tg4	701	58	GRIF1	GRIF1	NNS
cord-310847-63gh2tg4	701	59	from	from	IN
cord-310847-63gh2tg4	701	60	the	the	DT
cord-310847-63gh2tg4	701	61	cytoplasm	cytoplasm	NN
cord-310847-63gh2tg4	701	62	to	to	IN
cord-310847-63gh2tg4	701	63	the	the	DT
cord-310847-63gh2tg4	701	64	mitochondrion	mitochondrion	NN
cord-310847-63gh2tg4	701	65	and	and	CC
cord-310847-63gh2tg4	701	66	(	(	-LRB-
cord-310847-63gh2tg4	701	67	4	4	LS
cord-310847-63gh2tg4	701	68	)	)	-RRB-
cord-310847-63gh2tg4	701	69	plays	play	VBZ
cord-310847-63gh2tg4	701	70	a	a	DT
cord-310847-63gh2tg4	701	71	role	role	NN
cord-310847-63gh2tg4	701	72	in	in	IN
cord-310847-63gh2tg4	701	73	steroidogenesis	steroidogenesis	NN
cord-310847-63gh2tg4	701	74	through	through	IN
cord-310847-63gh2tg4	701	75	maintenance	maintenance	NN
cord-310847-63gh2tg4	701	76	of	of	IN
cord-310847-63gh2tg4	701	77	mitochondrial	mitochondrial	JJ
cord-310847-63gh2tg4	701	78	abundance	abundance	NN
cord-310847-63gh2tg4	701	79	and	and	CC
cord-310847-63gh2tg4	701	80	morphology	morphology	NN
cord-310847-63gh2tg4	701	81	.	.	.
cord-310847-63gh2tg4	702	1	211	211	CD
cord-310847-63gh2tg4	702	2	,	,	,
cord-310847-63gh2tg4	702	3	212	212	CD
cord-310847-63gh2tg4	702	4	There	there	EX
cord-310847-63gh2tg4	702	5	are	be	VBP
cord-310847-63gh2tg4	702	6	283	283	CD
cord-310847-63gh2tg4	702	7	residues	residue	NNS
cord-310847-63gh2tg4	702	8	in	in	IN
cord-310847-63gh2tg4	702	9	mouse	mouse	NN
cord-310847-63gh2tg4	702	10	MGARP	MGARP	NNP
cord-310847-63gh2tg4	702	11	,	,	,
cord-310847-63gh2tg4	702	12	49	49	CD
cord-310847-63gh2tg4	702	13	of	of	IN
cord-310847-63gh2tg4	702	14	which	which	WDT
cord-310847-63gh2tg4	702	15	are	be	VBP
cord-310847-63gh2tg4	702	16	glutamic	glutamic	JJ
cord-310847-63gh2tg4	702	17	acids	acid	NNS
cord-310847-63gh2tg4	702	18	exclusively	exclusively	RB
cord-310847-63gh2tg4	702	19	located	locate	VBN
cord-310847-63gh2tg4	702	20	in	in	IN
cord-310847-63gh2tg4	702	21	the	the	DT
cord-310847-63gh2tg4	702	22	Glu	Glu	NNP
cord-310847-63gh2tg4	702	23	-	-	HYPH
cord-310847-63gh2tg4	702	24	rich	rich	JJ
cord-310847-63gh2tg4	702	25	region	region	NN
cord-310847-63gh2tg4	702	26	(	(	-LRB-
cord-310847-63gh2tg4	702	27	residues	residue	NNS
cord-310847-63gh2tg4	702	28	79	79	CD
cord-310847-63gh2tg4	702	29	-	-	SYM
cord-310847-63gh2tg4	702	30	277	277	CD
cord-310847-63gh2tg4	702	31	)	)	-RRB-
cord-310847-63gh2tg4	702	32	.	.	.
cord-310847-63gh2tg4	703	1	Based	base	VBN
cord-310847-63gh2tg4	703	2	on	on	IN
cord-310847-63gh2tg4	703	3	the	the	DT
cord-310847-63gh2tg4	703	4	spectroscopic	spectroscopic	JJ
cord-310847-63gh2tg4	703	5	analysis	analysis	NN
cord-310847-63gh2tg4	703	6	of	of	IN
cord-310847-63gh2tg4	703	7	this	this	DT
cord-310847-63gh2tg4	703	8	protein	protein	NN
cord-310847-63gh2tg4	703	9	,	,	,
cord-310847-63gh2tg4	703	10	it	-PRON-	PRP
cord-310847-63gh2tg4	703	11	has	have	VBZ
cord-310847-63gh2tg4	703	12	been	be	VBN
cord-310847-63gh2tg4	703	13	concluded	conclude	VBN
cord-310847-63gh2tg4	703	14	that	that	IN
cord-310847-63gh2tg4	703	15	mouse	mouse	NN
cord-310847-63gh2tg4	703	16	GARP	GARP	NNP
cord-310847-63gh2tg4	703	17	is	be	VBZ
cord-310847-63gh2tg4	703	18	an	an	DT
cord-310847-63gh2tg4	703	19	IDP	IDP	NNP
cord-310847-63gh2tg4	703	20	.	.	.
cord-310847-63gh2tg4	704	1	209	209	CD
cord-310847-63gh2tg4	705	1	Some	some	DT
cord-310847-63gh2tg4	705	2	other	other	JJ
cord-310847-63gh2tg4	705	3	GARPs	garp	NNS
cord-310847-63gh2tg4	705	4	.	.	.
cord-310847-63gh2tg4	706	1	The	the	DT
cord-310847-63gh2tg4	706	2	life	life	NN
cord-310847-63gh2tg4	706	3	cycle	cycle	NN
cord-310847-63gh2tg4	706	4	of	of	IN
cord-310847-63gh2tg4	706	5	the	the	DT
cord-310847-63gh2tg4	706	6	phytopathogenic	phytopathogenic	JJ
cord-310847-63gh2tg4	706	7	fungus	fungus	NN
cord-310847-63gh2tg4	706	8	Verticillium	Verticillium	NNP
cord-310847-63gh2tg4	706	9	dahliae	dahliae	NN
cord-310847-63gh2tg4	706	10	Kleb	Kleb	NNP
cord-310847-63gh2tg4	706	11	causing	cause	VBG
cord-310847-63gh2tg4	706	12	wilt	wilt	NN
cord-310847-63gh2tg4	706	13	disease	disease	NN
cord-310847-63gh2tg4	706	14	in	in	IN
cord-310847-63gh2tg4	706	15	a	a	DT
cord-310847-63gh2tg4	706	16	wide	wide	JJ
cord-310847-63gh2tg4	706	17	range	range	NN
cord-310847-63gh2tg4	706	18	of	of	IN
cord-310847-63gh2tg4	706	19	crops	crop	NNS
cord-310847-63gh2tg4	706	20	,	,	,
cord-310847-63gh2tg4	706	21	including	include	VBG
cord-310847-63gh2tg4	706	22	cotton	cotton	NN
cord-310847-63gh2tg4	706	23	,	,	,
cord-310847-63gh2tg4	706	24	includes	include	VBZ
cord-310847-63gh2tg4	706	25	three	three	CD
cord-310847-63gh2tg4	706	26	vegetative	vegetative	JJ
cord-310847-63gh2tg4	706	27	phases	phase	NNS
cord-310847-63gh2tg4	706	28	:	:	:
cord-310847-63gh2tg4	706	29	parasitic	parasitic	JJ
cord-310847-63gh2tg4	706	30	,	,	,
cord-310847-63gh2tg4	706	31	saprophytic	saprophytic	JJ
cord-310847-63gh2tg4	706	32	and	and	CC
cord-310847-63gh2tg4	706	33	dormant	dormant	JJ
cord-310847-63gh2tg4	706	34	.	.	.
cord-310847-63gh2tg4	707	1	213	213	CD
cord-310847-63gh2tg4	707	2	One	one	CD
cord-310847-63gh2tg4	707	3	of	of	IN
cord-310847-63gh2tg4	707	4	the	the	DT
cord-310847-63gh2tg4	707	5	genes	gene	NNS
cord-310847-63gh2tg4	707	6	tagged	tag	VBN
cord-310847-63gh2tg4	707	7	in	in	IN
cord-310847-63gh2tg4	707	8	a	a	DT
cord-310847-63gh2tg4	707	9	pathogenicity	pathogenicity	NN
cord-310847-63gh2tg4	707	10	encoded	encode	VBD
cord-310847-63gh2tg4	707	11	a	a	DT
cord-310847-63gh2tg4	707	12	glutamic	glutamic	JJ
cord-310847-63gh2tg4	707	13	acid	acid	NN
cord-310847-63gh2tg4	707	14	-	-	HYPH
cord-310847-63gh2tg4	707	15	rich	rich	JJ
cord-310847-63gh2tg4	707	16	protein	protein	NN
cord-310847-63gh2tg4	707	17	(	(	-LRB-
cord-310847-63gh2tg4	707	18	VdGARP1	VdGARP1	NNP
cord-310847-63gh2tg4	707	19	)	)	-RRB-
cord-310847-63gh2tg4	707	20	,	,	,
cord-310847-63gh2tg4	707	21	which	which	WDT
cord-310847-63gh2tg4	707	22	shared	share	VBD
cord-310847-63gh2tg4	707	23	no	no	DT
cord-310847-63gh2tg4	707	24	significant	significant	JJ
cord-310847-63gh2tg4	707	25	similarity	similarity	NN
cord-310847-63gh2tg4	707	26	to	to	IN
cord-310847-63gh2tg4	707	27	any	any	DT
cord-310847-63gh2tg4	707	28	known	know	VBN
cord-310847-63gh2tg4	707	29	proteins	protein	NNS
cord-310847-63gh2tg4	707	30	.	.	.
cord-310847-63gh2tg4	708	1	213	213	CD
cord-310847-63gh2tg4	708	2	linked	link	VBD
cord-310847-63gh2tg4	708	3	to	to	IN
cord-310847-63gh2tg4	708	4	a	a	DT
cord-310847-63gh2tg4	708	5	glutamic	glutamic	NN
cord-310847-63gh2tg4	708	6	acid	acid	NN
cord-310847-63gh2tg4	708	7	and	and	CC
cord-310847-63gh2tg4	708	8	alanine	alanine	NN
cord-310847-63gh2tg4	708	9	repeat	repeat	NN
cord-310847-63gh2tg4	708	10	(	(	-LRB-
cord-310847-63gh2tg4	708	11	EG	EG	NNP
cord-310847-63gh2tg4	708	12	-	-	HYPH
cord-310847-63gh2tg4	708	13	EA	EA	NNP
cord-310847-63gh2tg4	708	14	repeat	repeat	NN
cord-310847-63gh2tg4	708	15	)	)	-RRB-
cord-310847-63gh2tg4	708	16	.	.	.
cord-310847-63gh2tg4	709	1	235	235	CD
cord-310847-63gh2tg4	710	1	There	there	EX
cord-310847-63gh2tg4	710	2	are	be	VBP
cord-310847-63gh2tg4	710	3	171	171	CD
cord-310847-63gh2tg4	710	4	,	,	,
cord-310847-63gh2tg4	710	5	83	83	CD
cord-310847-63gh2tg4	710	6	and	and	CC
cord-310847-63gh2tg4	710	7	43	43	CD
cord-310847-63gh2tg4	710	8	glutamic	glutamic	NN
cord-310847-63gh2tg4	710	9	acids	acid	NNS
cord-310847-63gh2tg4	710	10	,	,	,
cord-310847-63gh2tg4	710	11	glycines	glycine	NNS
cord-310847-63gh2tg4	710	12	and	and	CC
cord-310847-63gh2tg4	710	13	alanines	alanine	NNS
cord-310847-63gh2tg4	710	14	in	in	IN
cord-310847-63gh2tg4	710	15	this	this	DT
cord-310847-63gh2tg4	710	16	latency	latency	NN
cord-310847-63gh2tg4	710	17	associated	associate	VBD
cord-310847-63gh2tg4	710	18	nuclear	nuclear	JJ
cord-310847-63gh2tg4	710	19	antigen	antigen	NN
cord-310847-63gh2tg4	710	20	.	.	.
cord-310847-63gh2tg4	711	1	Although	although	IN
cord-310847-63gh2tg4	711	2	there	there	EX
cord-310847-63gh2tg4	711	3	is	be	VBZ
cord-310847-63gh2tg4	711	4	low	low	JJ
cord-310847-63gh2tg4	711	5	sequence	sequence	NN
cord-310847-63gh2tg4	711	6	identity	identity	NN
cord-310847-63gh2tg4	711	7	between	between	IN
cord-310847-63gh2tg4	711	8	LANA1	lana1	NN
cord-310847-63gh2tg4	711	9	,	,	,
cord-310847-63gh2tg4	711	10	EBNA1	EBNA1	NNP
cord-310847-63gh2tg4	711	11	and	and	CC
cord-310847-63gh2tg4	711	12	ORF73	ORF73	NNP
cord-310847-63gh2tg4	711	13	,	,	,
cord-310847-63gh2tg4	711	14	all	all	DT
cord-310847-63gh2tg4	711	15	three	three	CD
cord-310847-63gh2tg4	711	16	proteins	protein	NNS
cord-310847-63gh2tg4	711	17	determine	determine	VBP
cord-310847-63gh2tg4	711	18	the	the	DT
cord-310847-63gh2tg4	711	19	poor	poor	JJ
cord-310847-63gh2tg4	711	20	recognition	recognition	NN
cord-310847-63gh2tg4	711	21	of	of	IN
cord-310847-63gh2tg4	711	22	viruses	virus	NNS
cord-310847-63gh2tg4	711	23	by	by	IN
cord-310847-63gh2tg4	711	24	CD8	CD8	NNP
cord-310847-63gh2tg4	711	25	+	+	CC
cord-310847-63gh2tg4	711	26	cytotoxic	cytotoxic	JJ
cord-310847-63gh2tg4	711	27	T	t	NN
cord-310847-63gh2tg4	711	28	lymphocytes	lymphocyte	NNS
cord-310847-63gh2tg4	711	29	(	(	-LRB-
cord-310847-63gh2tg4	711	30	CTL	CTL	NNP
cord-310847-63gh2tg4	711	31	)	)	-RRB-
cord-310847-63gh2tg4	711	32	.	.	.
cord-310847-63gh2tg4	712	1	However	however	RB
cord-310847-63gh2tg4	712	2	,	,	,
cord-310847-63gh2tg4	712	3	the	the	DT
cord-310847-63gh2tg4	712	4	mechanisms	mechanism	NNS
cord-310847-63gh2tg4	712	5	of	of	IN
cord-310847-63gh2tg4	712	6	their	-PRON-	PRP$
cord-310847-63gh2tg4	712	7	action	action	NN
cord-310847-63gh2tg4	712	8	are	be	VBP
cord-310847-63gh2tg4	712	9	rather	rather	RB
cord-310847-63gh2tg4	712	10	different	different	JJ
cord-310847-63gh2tg4	712	11	.	.	.
cord-310847-63gh2tg4	713	1	In	in	IN
cord-310847-63gh2tg4	713	2	the	the	DT
cord-310847-63gh2tg4	713	3	Epstein	Epstein	NNP
cord-310847-63gh2tg4	713	4	-	-	HYPH
cord-310847-63gh2tg4	713	5	Barr	Barr	NNP
cord-310847-63gh2tg4	713	6	virus	virus	NN
cord-310847-63gh2tg4	713	7	and	and	CC
cord-310847-63gh2tg4	713	8	Kaposi	Kaposi	NNP
cord-310847-63gh2tg4	713	9	's	's	POS
cord-310847-63gh2tg4	713	10	sarcoma	sarcoma	NN
cord-310847-63gh2tg4	713	11	-	-	HYPH
cord-310847-63gh2tg4	713	12	associated	associate	VBN
cord-310847-63gh2tg4	713	13	herpesvirus	herpesvirus	NN
cord-310847-63gh2tg4	713	14	the	the	DT
cord-310847-63gh2tg4	713	15	repeat	repeat	NN
cord-310847-63gh2tg4	713	16	domains	domain	NNS
cord-310847-63gh2tg4	713	17	were	be	VBD
cord-310847-63gh2tg4	713	18	shown	show	VBN
cord-310847-63gh2tg4	713	19	to	to	TO
cord-310847-63gh2tg4	713	20	enhance	enhance	VB
cord-310847-63gh2tg4	713	21	the	the	DT
cord-310847-63gh2tg4	713	22	stability	stability	NN
cord-310847-63gh2tg4	713	23	of	of	IN
cord-310847-63gh2tg4	713	24	EBNA1	EBNA1	NNS
cord-310847-63gh2tg4	713	25	and	and	CC
cord-310847-63gh2tg4	713	26	LANA1	LANA1	NNP
cord-310847-63gh2tg4	713	27	and	and	CC
cord-310847-63gh2tg4	713	28	decrease	decrease	VB
cord-310847-63gh2tg4	713	29	their	-PRON-	PRP$
cord-310847-63gh2tg4	713	30	translation	translation	NN
cord-310847-63gh2tg4	713	31	rates	rate	NNS
cord-310847-63gh2tg4	713	32	,	,	,
cord-310847-63gh2tg4	713	33	whereas	whereas	IN
cord-310847-63gh2tg4	713	34	the	the	DT
cord-310847-63gh2tg4	713	35	EG	EG	NNP
cord-310847-63gh2tg4	713	36	-	-	HYPH
cord-310847-63gh2tg4	713	37	EA	EA	NNP
cord-310847-63gh2tg4	713	38	repeat	repeat	NN
cord-310847-63gh2tg4	713	39	has	have	VBZ
cord-310847-63gh2tg4	713	40	no	no	DT
cord-310847-63gh2tg4	713	41	effect	effect	NN
cord-310847-63gh2tg4	713	42	on	on	IN
cord-310847-63gh2tg4	713	43	the	the	DT
cord-310847-63gh2tg4	713	44	stability	stability	NN
cord-310847-63gh2tg4	713	45	of	of	IN
cord-310847-63gh2tg4	713	46	HVS	HVS	NNP
cord-310847-63gh2tg4	713	47	ORF73	ORF73	NNP
cord-310847-63gh2tg4	713	48	or	or	CC
cord-310847-63gh2tg4	713	49	its	-PRON-	PRP$
cord-310847-63gh2tg4	713	50	rate	rate	NN
cord-310847-63gh2tg4	713	51	of	of	IN
cord-310847-63gh2tg4	713	52	translation	translation	NN
cord-310847-63gh2tg4	713	53	,	,	,
cord-310847-63gh2tg4	713	54	but	but	CC
cord-310847-63gh2tg4	713	55	results	result	NNS
cord-310847-63gh2tg4	713	56	in	in	IN
cord-310847-63gh2tg4	713	57	decreased	decrease	VBD
cord-310847-63gh2tg4	713	58	steady	steady	JJ
cord-310847-63gh2tg4	713	59	-	-	HYPH
cord-310847-63gh2tg4	713	60	state	state	NN
cord-310847-63gh2tg4	713	61	levels	level	NNS
cord-310847-63gh2tg4	713	62	of	of	IN
cord-310847-63gh2tg4	713	63	ORF73	ORF73	NNP
cord-310847-63gh2tg4	713	64	mRNA	mRNA	NNP
cord-310847-63gh2tg4	713	65	.	.	.
cord-310847-63gh2tg4	714	1	235	235	CD
cord-310847-63gh2tg4	715	1	Intriguingly	intriguingly	RB
cord-310847-63gh2tg4	715	2	,	,	,
cord-310847-63gh2tg4	715	3	the	the	DT
cord-310847-63gh2tg4	715	4	motif	motif	NN
cord-310847-63gh2tg4	715	5	EEAEEAEEE	EEAEEAEEE	NNP
cord-310847-63gh2tg4	715	6	of	of	IN
cord-310847-63gh2tg4	715	7	HVS	HVS	NNP
cord-310847-63gh2tg4	715	8	ORF73	ORF73	NNP
cord-310847-63gh2tg4	715	9	was	be	VBD
cord-310847-63gh2tg4	715	10	sufficient	sufficient	JJ
cord-310847-63gh2tg4	715	11	to	to	TO
cord-310847-63gh2tg4	715	12	cause	cause	VB
cord-310847-63gh2tg4	715	13	a	a	DT
cord-310847-63gh2tg4	715	14	reduction	reduction	NN
cord-310847-63gh2tg4	715	15	in	in	IN
cord-310847-63gh2tg4	715	16	recognition	recognition	NN
cord-310847-63gh2tg4	715	17	of	of	IN
cord-310847-63gh2tg4	715	18	ORF73	ORF73	NNP
cord-310847-63gh2tg4	715	19	by	by	IN
cord-310847-63gh2tg4	715	20	CD8	CD8	NNP
cord-310847-63gh2tg4	715	21	+	+	SYM
cord-310847-63gh2tg4	715	22	CTL	CTL	NNP
cord-310847-63gh2tg4	715	23	,	,	,
cord-310847-63gh2tg4	715	24	suggesting	suggest	VBG
cord-310847-63gh2tg4	715	25	that	that	IN
cord-310847-63gh2tg4	715	26	the	the	DT
cord-310847-63gh2tg4	715	27	EG	EG	NNP
cord-310847-63gh2tg4	715	28	-	-	HYPH
cord-310847-63gh2tg4	715	29	EA	ea	NN
cord-310847-63gh2tg4	715	30	repeat	repeat	NN
cord-310847-63gh2tg4	715	31	of	of	IN
cord-310847-63gh2tg4	715	32	HVS	HVS	NNP
cord-310847-63gh2tg4	715	33	ORF73	ORF73	NNP
cord-310847-63gh2tg4	715	34	is	be	VBZ
cord-310847-63gh2tg4	715	35	crucial	crucial	JJ
cord-310847-63gh2tg4	715	36	for	for	IN
cord-310847-63gh2tg4	715	37	the	the	DT
cord-310847-63gh2tg4	715	38	immune	immune	JJ
cord-310847-63gh2tg4	715	39	evasion	evasion	NN
cord-310847-63gh2tg4	715	40	.	.	.
cord-310847-63gh2tg4	716	1	235	235	CD
cord-310847-63gh2tg4	716	2	Nsp3a	Nsp3a	NNS
cord-310847-63gh2tg4	716	3	.	.	.
cord-310847-63gh2tg4	717	1	The	the	DT
cord-310847-63gh2tg4	717	2	N	n	CD
cord-310847-63gh2tg4	717	3	-	-	HYPH
cord-310847-63gh2tg4	717	4	terminal	terminal	NN
cord-310847-63gh2tg4	717	5	domain	domain	NN
cord-310847-63gh2tg4	717	6	of	of	IN
cord-310847-63gh2tg4	717	7	the	the	DT
cord-310847-63gh2tg4	717	8	severe	severe	JJ
cord-310847-63gh2tg4	717	9	acute	acute	JJ
cord-310847-63gh2tg4	717	10	respiratory	respiratory	JJ
cord-310847-63gh2tg4	717	11	syndrome	syndrome	NN
cord-310847-63gh2tg4	717	12	coronavirus	coronavirus	NN
cord-310847-63gh2tg4	717	13	(	(	-LRB-
cord-310847-63gh2tg4	717	14	SARS	SARS	NNP
cord-310847-63gh2tg4	717	15	-	-	HYPH
cord-310847-63gh2tg4	717	16	CoV	CoV	NNP
cord-310847-63gh2tg4	717	17	)	)	-RRB-
cord-310847-63gh2tg4	717	18	nonstructural	nonstructural	JJ
cord-310847-63gh2tg4	717	19	protein	protein	NNP
cord-310847-63gh2tg4	717	20	3	3	CD
cord-310847-63gh2tg4	717	21	(	(	-LRB-
cord-310847-63gh2tg4	717	22	nsp3a	nsp3a	NNP
cord-310847-63gh2tg4	717	23	)	)	-RRB-
cord-310847-63gh2tg4	717	24	is	be	VBZ
cord-310847-63gh2tg4	717	25	a	a	DT
cord-310847-63gh2tg4	717	26	typical	typical	JJ
cord-310847-63gh2tg4	717	27	IDP	idp	NN
cord-310847-63gh2tg4	717	28	of	of	IN
cord-310847-63gh2tg4	717	29	183	183	CD
cord-310847-63gh2tg4	717	30	residues	residue	NNS
cord-310847-63gh2tg4	717	31	characterized	characterize	VBN
cord-310847-63gh2tg4	717	32	by	by	IN
cord-310847-63gh2tg4	717	33	the	the	DT
cord-310847-63gh2tg4	717	34	presence	presence	NN
cord-310847-63gh2tg4	717	35	of	of	IN
cord-310847-63gh2tg4	717	36	an	an	DT
cord-310847-63gh2tg4	717	37	ubiquitin	ubiquitin	NN
cord-310847-63gh2tg4	717	38	-	-	HYPH
cord-310847-63gh2tg4	717	39	like	like	JJ
cord-310847-63gh2tg4	717	40	globular	globular	JJ
cord-310847-63gh2tg4	717	41	domain	domain	NN
cord-310847-63gh2tg4	717	42	(	(	-LRB-
cord-310847-63gh2tg4	717	43	residues	residue	NNS
cord-310847-63gh2tg4	717	44	1	1	CD
cord-310847-63gh2tg4	717	45	-	-	SYM
cord-310847-63gh2tg4	717	46	112	112	CD
cord-310847-63gh2tg4	717	47	)	)	-RRB-
cord-310847-63gh2tg4	717	48	and	and	CC
cord-310847-63gh2tg4	717	49	a	a	DT
cord-310847-63gh2tg4	717	50	flexible	flexible	JJ
cord-310847-63gh2tg4	717	51	,	,	,
cord-310847-63gh2tg4	717	52	highly	highly	RB
cord-310847-63gh2tg4	717	53	extended	extend	VBN
cord-310847-63gh2tg4	717	54	Glu	Glu	NNP
cord-310847-63gh2tg4	717	55	-	-	HYPH
cord-310847-63gh2tg4	717	56	rich	rich	JJ
cord-310847-63gh2tg4	717	57	domain	domain	NN
cord-310847-63gh2tg4	717	58	(	(	-LRB-
cord-310847-63gh2tg4	717	59	residues	residue	NNS
cord-310847-63gh2tg4	717	60	.	.	.
cord-310847-63gh2tg4	718	1	236	236	CD
cord-310847-63gh2tg4	718	2	Nsp3a	Nsp3a	NNP
cord-310847-63gh2tg4	718	3	is	be	VBZ
cord-310847-63gh2tg4	718	4	a	a	DT
cord-310847-63gh2tg4	718	5	highly	highly	RB
cord-310847-63gh2tg4	718	6	acidic	acidic	JJ
cord-310847-63gh2tg4	718	7	protein	protein	NN
cord-310847-63gh2tg4	718	8	(	(	-LRB-
cord-310847-63gh2tg4	718	9	pH	pH	NNP
cord-310847-63gh2tg4	718	10	3.72	3.72	CD
cord-310847-63gh2tg4	718	11	)	)	-RRB-
cord-310847-63gh2tg4	718	12	that	that	WDT
cord-310847-63gh2tg4	718	13	contains	contain	VBZ
cord-310847-63gh2tg4	718	14	40	40	CD
cord-310847-63gh2tg4	718	15	glutamic	glutamic	NN
cord-310847-63gh2tg4	718	16	acids	acid	NNS
cord-310847-63gh2tg4	718	17	,	,	,
cord-310847-63gh2tg4	718	18	28	28	CD
cord-310847-63gh2tg4	718	19	of	of	IN
cord-310847-63gh2tg4	718	20	which	which	WDT
cord-310847-63gh2tg4	718	21	are	be	VBP
cord-310847-63gh2tg4	718	22	located	locate	VBN
cord-310847-63gh2tg4	718	23	within	within	IN
cord-310847-63gh2tg4	718	24	the	the	DT
cord-310847-63gh2tg4	718	25	C	C	NNP
cord-310847-63gh2tg4	718	26	-	-	HYPH
cord-310847-63gh2tg4	718	27	terminal	terminal	NN
cord-310847-63gh2tg4	718	28	Glu	Glu	NNP
cord-310847-63gh2tg4	718	29	-	-	HYPH
cord-310847-63gh2tg4	718	30	rich	rich	JJ
cord-310847-63gh2tg4	718	31	domain	domain	NN
cord-310847-63gh2tg4	718	32	.	.	.
cord-310847-63gh2tg4	719	1	PPE	PPE	NNP
cord-310847-63gh2tg4	719	2	antigens	antigen	NNS
cord-310847-63gh2tg4	719	3	.	.	.
cord-310847-63gh2tg4	720	1	Proline	proline	NN
cord-310847-63gh2tg4	720	2	and	and	CC
cord-310847-63gh2tg4	720	3	glutamic	glutamic	NN
cord-310847-63gh2tg4	720	4	acid	acid	NN
cord-310847-63gh2tg4	720	5	rich	rich	JJ
cord-310847-63gh2tg4	720	6	proteins	protein	NNS
cord-310847-63gh2tg4	720	7	(	(	-LRB-
cord-310847-63gh2tg4	720	8	or	or	CC
cord-310847-63gh2tg4	720	9	PPErepeat	PPErepeat	NNP
cord-310847-63gh2tg4	720	10	containing	contain	VBG
cord-310847-63gh2tg4	720	11	proteins	protein	NNS
cord-310847-63gh2tg4	720	12	,	,	,
cord-310847-63gh2tg4	720	13	or	or	CC
cord-310847-63gh2tg4	720	14	PPE	PPE	NNP
cord-310847-63gh2tg4	720	15	proteins	protein	NNS
cord-310847-63gh2tg4	720	16	)	)	-RRB-
cord-310847-63gh2tg4	720	17	are	be	VBP
cord-310847-63gh2tg4	720	18	important	important	JJ
cord-310847-63gh2tg4	720	19	T	t	NN
cord-310847-63gh2tg4	720	20	-	-	HYPH
cord-310847-63gh2tg4	720	21	cell	cell	NN
cord-310847-63gh2tg4	720	22	antigens	antigen	NNS
cord-310847-63gh2tg4	720	23	produced	produce	VBN
cord-310847-63gh2tg4	720	24	by	by	IN
cord-310847-63gh2tg4	720	25	Mycobacterium	Mycobacterium	NNP
cord-310847-63gh2tg4	720	26	avium	avium	NN
cord-310847-63gh2tg4	720	27	subsp	subsp	NN
cord-310847-63gh2tg4	720	28	Paratuberculosis	Paratuberculosis	NNP
cord-310847-63gh2tg4	720	29	(	(	-LRB-
cord-310847-63gh2tg4	720	30	Map	Map	NNP
cord-310847-63gh2tg4	720	31	)	)	-RRB-
cord-310847-63gh2tg4	720	32	.	.	.
cord-310847-63gh2tg4	721	1	237	237	CD
cord-310847-63gh2tg4	721	2	One	one	CD
cord-310847-63gh2tg4	721	3	of	of	IN
cord-310847-63gh2tg4	721	4	the	the	DT
cord-310847-63gh2tg4	721	5	PPEs	ppe	NNS
cord-310847-63gh2tg4	721	6	is	be	VBZ
cord-310847-63gh2tg4	721	7	a	a	DT
cord-310847-63gh2tg4	721	8	34.9	34.9	CD
cord-310847-63gh2tg4	721	9	kDa	kDa	NNP
cord-310847-63gh2tg4	721	10	protein	protein	NN
cord-310847-63gh2tg4	721	11	(	(	-LRB-
cord-310847-63gh2tg4	721	12	359	359	CD
cord-310847-63gh2tg4	721	13	residues	residue	NNS
cord-310847-63gh2tg4	721	14	,	,	,
cord-310847-63gh2tg4	721	15	pI	pI	NNP
cord-310847-63gh2tg4	721	16	4.31	4.31	CD
cord-310847-63gh2tg4	721	17	)	)	-RRB-
cord-310847-63gh2tg4	721	18	which	which	WDT
cord-310847-63gh2tg4	721	19	following	follow	VBG
cord-310847-63gh2tg4	721	20	recombinant	recombinant	JJ
cord-310847-63gh2tg4	721	21	expression	expression	NN
cord-310847-63gh2tg4	721	22	in	in	IN
cord-310847-63gh2tg4	721	23	E.	E.	NNP
cord-310847-63gh2tg4	721	24	coli	coli	NNS
cord-310847-63gh2tg4	721	25	was	be	VBD
cord-310847-63gh2tg4	721	26	shown	show	VBN
cord-310847-63gh2tg4	721	27	to	to	TO
cord-310847-63gh2tg4	721	28	elicit	elicit	VB
cord-310847-63gh2tg4	721	29	significant	significant	JJ
cord-310847-63gh2tg4	721	30	delayed	delay	VBN
cord-310847-63gh2tg4	721	31	type	type	NN
cord-310847-63gh2tg4	721	32	hypersensitivity	hypersensitivity	NN
cord-310847-63gh2tg4	721	33	skin	skin	NN
cord-310847-63gh2tg4	721	34	reaction	reaction	NN
cord-310847-63gh2tg4	721	35	in	in	IN
cord-310847-63gh2tg4	721	36	mice	mouse	NNS
cord-310847-63gh2tg4	721	37	sensitized	sensitize	VBN
cord-310847-63gh2tg4	721	38	with	with	IN
cord-310847-63gh2tg4	721	39	Map	Map	NNP
cord-310847-63gh2tg4	721	40	,	,	,
cord-310847-63gh2tg4	721	41	suggesting	suggest	VBG
cord-310847-63gh2tg4	721	42	that	that	IN
cord-310847-63gh2tg4	721	43	this	this	DT
cord-310847-63gh2tg4	721	44	recombinant	recombinant	JJ
cord-310847-63gh2tg4	721	45	PPE	PPE	NNP
cord-310847-63gh2tg4	721	46	protein	protein	NN
cord-310847-63gh2tg4	721	47	of	of	IN
cord-310847-63gh2tg4	721	48	Map	Map	NNP
cord-310847-63gh2tg4	721	49	was	be	VBD
cord-310847-63gh2tg4	721	50	definitely	definitely	RB
cord-310847-63gh2tg4	721	51	associated	associate	VBN
cord-310847-63gh2tg4	721	52	with	with	IN
cord-310847-63gh2tg4	721	53	cellular	cellular	JJ
cord-310847-63gh2tg4	721	54	immune	immune	JJ
cord-310847-63gh2tg4	721	55	response	response	NN
cord-310847-63gh2tg4	721	56	.	.	.
cord-310847-63gh2tg4	722	1	237	237	CD
cord-310847-63gh2tg4	723	1	Curiously	curiously	RB
cord-310847-63gh2tg4	723	2	,	,	,
cord-310847-63gh2tg4	723	3	this	this	DT
cord-310847-63gh2tg4	723	4	PPE	PPE	NNP
cord-310847-63gh2tg4	723	5	contains	contain	VBZ
cord-310847-63gh2tg4	723	6	73	73	CD
cord-310847-63gh2tg4	723	7	alanines	alanine	NNS
cord-310847-63gh2tg4	723	8	,	,	,
cord-310847-63gh2tg4	723	9	44	44	CD
cord-310847-63gh2tg4	723	10	glycines	glycine	NNS
cord-310847-63gh2tg4	723	11	,	,	,
cord-310847-63gh2tg4	723	12	37	37	CD
cord-310847-63gh2tg4	723	13	prolines	proline	NNS
cord-310847-63gh2tg4	723	14	,	,	,
cord-310847-63gh2tg4	723	15	20	20	CD
cord-310847-63gh2tg4	723	16	aspartic	aspartic	JJ
cord-310847-63gh2tg4	723	17	acids	acid	NNS
cord-310847-63gh2tg4	723	18	but	but	CC
cord-310847-63gh2tg4	723	19	just	just	RB
cord-310847-63gh2tg4	723	20	10	10	CD
cord-310847-63gh2tg4	723	21	glutamic	glutamic	NN
cord-310847-63gh2tg4	723	22	acids	acid	NNS
cord-310847-63gh2tg4	723	23	.	.	.
cord-310847-63gh2tg4	724	1	Pt2L4	Pt2L4	NNP
cord-310847-63gh2tg4	724	2	.	.	.
cord-310847-63gh2tg4	725	1	Cassava	cassava	NN
cord-310847-63gh2tg4	725	2	storage	storage	NN
cord-310847-63gh2tg4	725	3	roots	root	NNS
cord-310847-63gh2tg4	725	4	differentially	differentially	RB
cord-310847-63gh2tg4	725	5	produce	produce	VBP
cord-310847-63gh2tg4	725	6	an	an	DT
cord-310847-63gh2tg4	725	7	interesting	interesting	JJ
cord-310847-63gh2tg4	725	8	Pt2L4	Pt2L4	NNP
cord-310847-63gh2tg4	725	9	protein	protein	NN
cord-310847-63gh2tg4	725	10	238	238	CD
cord-310847-63gh2tg4	725	11	with	with	IN
cord-310847-63gh2tg4	725	12	low	low	JJ
cord-310847-63gh2tg4	725	13	sequence	sequence	NN
cord-310847-63gh2tg4	725	14	complexity	complexity	NN
cord-310847-63gh2tg4	725	15	characterized	characterize	VBN
cord-310847-63gh2tg4	725	16	by	by	IN
cord-310847-63gh2tg4	725	17	a	a	DT
cord-310847-63gh2tg4	725	18	reduced	reduce	VBN
cord-310847-63gh2tg4	725	19	amino	amino	NN
cord-310847-63gh2tg4	725	20	acid	acid	NN
cord-310847-63gh2tg4	725	21	alphabet	alphabet	NN
cord-310847-63gh2tg4	725	22	(	(	-LRB-
cord-310847-63gh2tg4	725	23	just	just	RB
cord-310847-63gh2tg4	725	24	13	13	CD
cord-310847-63gh2tg4	725	25	amino	amino	JJ
cord-310847-63gh2tg4	725	26	acids	acid	NNS
cord-310847-63gh2tg4	725	27	)	)	-RRB-
cord-310847-63gh2tg4	725	28	.	.	.
cord-310847-63gh2tg4	726	1	This	this	DT
cord-310847-63gh2tg4	726	2	107	107	CD
cord-310847-63gh2tg4	726	3	residue	residue	NN
cord-310847-63gh2tg4	726	4	-	-	HYPH
cord-310847-63gh2tg4	726	5	long	long	JJ
cord-310847-63gh2tg4	726	6	protein	protein	NN
cord-310847-63gh2tg4	726	7	contains	contain	VBZ
cord-310847-63gh2tg4	726	8	56	56	CD
cord-310847-63gh2tg4	726	9	glutamic	glutamic	NN
cord-310847-63gh2tg4	726	10	acids	acid	NNS
cord-310847-63gh2tg4	726	11	,	,	,
cord-310847-63gh2tg4	726	12	30	30	CD
cord-310847-63gh2tg4	726	13	alanines	alanine	NNS
cord-310847-63gh2tg4	726	14	,	,	,
cord-310847-63gh2tg4	726	15	24	24	CD
cord-310847-63gh2tg4	726	16	valines	valine	NNS
cord-310847-63gh2tg4	726	17	,	,	,
cord-310847-63gh2tg4	726	18	20	20	CD
cord-310847-63gh2tg4	726	19	prolines	proline	NNS
cord-310847-63gh2tg4	726	20	,	,	,
cord-310847-63gh2tg4	726	21	18	18	CD
cord-310847-63gh2tg4	726	22	serines	serines	NNPS
cord-310847-63gh2tg4	726	23	and	and	CC
cord-310847-63gh2tg4	726	24	15	15	CD
cord-310847-63gh2tg4	726	25	lysines	lysine	NNS
cord-310847-63gh2tg4	726	26	,	,	,
cord-310847-63gh2tg4	726	27	but	but	CC
cord-310847-63gh2tg4	726	28	does	do	VBZ
cord-310847-63gh2tg4	726	29	not	not	RB
cord-310847-63gh2tg4	726	30	have	have	VB
cord-310847-63gh2tg4	726	31	any	any	DT
cord-310847-63gh2tg4	726	32	arginines	arginine	NNS
cord-310847-63gh2tg4	726	33	,	,	,
cord-310847-63gh2tg4	726	34	asparagines	asparagines	NNP
cord-310847-63gh2tg4	726	35	,	,	,
cord-310847-63gh2tg4	726	36	cysteins	cysteins	NNP
cord-310847-63gh2tg4	726	37	,	,	,
cord-310847-63gh2tg4	726	38	histidines	histidines	NNP
cord-310847-63gh2tg4	726	39	,	,	,
cord-310847-63gh2tg4	726	40	phenylalanines	phenylalanines	NNP
cord-310847-63gh2tg4	726	41	,	,	,
cord-310847-63gh2tg4	726	42	tyrosines	tyrosines	NNPS
cord-310847-63gh2tg4	726	43	and	and	CC
cord-310847-63gh2tg4	726	44	tryptophanes	tryptophane	NNS
cord-310847-63gh2tg4	726	45	.	.	.
cord-310847-63gh2tg4	727	1	Glutamic	glutamic	NN
cord-310847-63gh2tg4	727	2	acid	acid	NN
cord-310847-63gh2tg4	727	3	-	-	HYPH
cord-310847-63gh2tg4	727	4	rich	rich	JJ
cord-310847-63gh2tg4	727	5	protein	protein	NN
cord-310847-63gh2tg4	727	6	from	from	IN
cord-310847-63gh2tg4	727	7	cassava	cassava	NN
cord-310847-63gh2tg4	727	8	roots	root	NNS
cord-310847-63gh2tg4	727	9	.	.	.
cord-310847-63gh2tg4	728	1	Based	base	VBN
cord-310847-63gh2tg4	728	2	on	on	IN
cord-310847-63gh2tg4	728	3	the	the	DT
cord-310847-63gh2tg4	728	4	analysis	analysis	NN
cord-310847-63gh2tg4	728	5	of	of	IN
cord-310847-63gh2tg4	728	6	changes	change	NNS
cord-310847-63gh2tg4	728	7	in	in	IN
cord-310847-63gh2tg4	728	8	the	the	DT
cord-310847-63gh2tg4	728	9	cassava	cassava	NN
cord-310847-63gh2tg4	728	10	root	root	NN
cord-310847-63gh2tg4	728	11	proteome	proteome	NN
cord-310847-63gh2tg4	728	12	during	during	IN
cord-310847-63gh2tg4	728	13	physiological	physiological	JJ
cord-310847-63gh2tg4	728	14	deterioration	deterioration	NN
cord-310847-63gh2tg4	728	15	of	of	IN
cord-310847-63gh2tg4	728	16	cassava	cassava	NN
cord-310847-63gh2tg4	728	17	root	root	NN
cord-310847-63gh2tg4	728	18	after	after	IN
cord-310847-63gh2tg4	728	19	harvesting	harvesting	NN
cord-310847-63gh2tg4	728	20	,	,	,
cord-310847-63gh2tg4	728	21	it	-PRON-	PRP
cord-310847-63gh2tg4	728	22	has	have	VBZ
cord-310847-63gh2tg4	728	23	been	be	VBN
cord-310847-63gh2tg4	728	24	concluded	conclude	VBN
cord-310847-63gh2tg4	728	25	that	that	IN
cord-310847-63gh2tg4	728	26	the	the	DT
cord-310847-63gh2tg4	728	27	glutamic	glutamic	NN
cord-310847-63gh2tg4	728	28	acid	acid	NN
cord-310847-63gh2tg4	728	29	-	-	HYPH
cord-310847-63gh2tg4	728	30	rich	rich	JJ
cord-310847-63gh2tg4	728	31	protein	protein	NN
cord-310847-63gh2tg4	728	32	was	be	VBD
cord-310847-63gh2tg4	728	33	one	one	CD
cord-310847-63gh2tg4	728	34	of	of	IN
cord-310847-63gh2tg4	728	35	the	the	DT
cord-310847-63gh2tg4	728	36	proteins	protein	NNS
cord-310847-63gh2tg4	728	37	that	that	WDT
cord-310847-63gh2tg4	728	38	were	be	VBD
cord-310847-63gh2tg4	728	39	upregulated	upregulate	VBN
cord-310847-63gh2tg4	728	40	after	after	IN
cord-310847-63gh2tg4	728	41	harvesting	harvest	VBG
cord-310847-63gh2tg4	728	42	.	.	.
cord-310847-63gh2tg4	729	1	239	239	CD
cord-310847-63gh2tg4	729	2	Cp190	Cp190	NNP
cord-310847-63gh2tg4	729	3	.	.	.
cord-310847-63gh2tg4	730	1	Eukaryotic	eukaryotic	JJ
cord-310847-63gh2tg4	730	2	genomes	genome	NNS
cord-310847-63gh2tg4	730	3	contain	contain	VBP
cord-310847-63gh2tg4	730	4	a	a	DT
cord-310847-63gh2tg4	730	5	set	set	NN
cord-310847-63gh2tg4	730	6	of	of	IN
cord-310847-63gh2tg4	730	7	specific	specific	JJ
cord-310847-63gh2tg4	730	8	functional	functional	JJ
cord-310847-63gh2tg4	730	9	elements	element	NNS
cord-310847-63gh2tg4	730	10	,	,	,
cord-310847-63gh2tg4	730	11	chromatin	chromatin	NN
cord-310847-63gh2tg4	730	12	insulators	insulator	NNS
cord-310847-63gh2tg4	730	13	or	or	CC
cord-310847-63gh2tg4	730	14	boundary	boundary	JJ
cord-310847-63gh2tg4	730	15	elements	element	NNS
cord-310847-63gh2tg4	730	16	that	that	WDT
cord-310847-63gh2tg4	730	17	regulate	regulate	VBP
cord-310847-63gh2tg4	730	18	gene	gene	NN
cord-310847-63gh2tg4	730	19	transcription	transcription	NN
cord-310847-63gh2tg4	730	20	by	by	IN
cord-310847-63gh2tg4	730	21	interfering	interfere	VBG
cord-310847-63gh2tg4	730	22	with	with	IN
cord-310847-63gh2tg4	730	23	promoterenhancer	promoterenhancer	NN
cord-310847-63gh2tg4	730	24	communication	communication	NN
cord-310847-63gh2tg4	730	25	.	.	.
cord-310847-63gh2tg4	731	1	240	240	CD
cord-310847-63gh2tg4	732	1	In	in	IN
cord-310847-63gh2tg4	732	2	Drosophila	Drosophila	NNP
cord-310847-63gh2tg4	732	3	melanogaster	melanogaster	NN
cord-310847-63gh2tg4	732	4	,	,	,
cord-310847-63gh2tg4	732	5	the	the	DT
cord-310847-63gh2tg4	732	6	centrosome	centrosome	NN
cord-310847-63gh2tg4	732	7	-	-	HYPH
cord-310847-63gh2tg4	732	8	associated	associate	VBN
cord-310847-63gh2tg4	732	9	zinc	zinc	NN
cord-310847-63gh2tg4	732	10	finger	finger	NN
cord-310847-63gh2tg4	732	11	protein	protein	NN
cord-310847-63gh2tg4	732	12	Cp190	Cp190	NNP
cord-310847-63gh2tg4	732	13	protein	protein	NN
cord-310847-63gh2tg4	732	14	(	(	-LRB-
cord-310847-63gh2tg4	732	15	Cp190	Cp190	NNP
cord-310847-63gh2tg4	732	16	)	)	-RRB-
cord-310847-63gh2tg4	732	17	is	be	VBZ
cord-310847-63gh2tg4	732	18	a	a	DT
cord-310847-63gh2tg4	732	19	component	component	NN
cord-310847-63gh2tg4	732	20	of	of	IN
cord-310847-63gh2tg4	732	21	the	the	DT
cord-310847-63gh2tg4	732	22	gypsy	gypsy	NNP
cord-310847-63gh2tg4	732	23	chromatin	chromatin	NNP
cord-310847-63gh2tg4	732	24	insulator	insulator	NN
cord-310847-63gh2tg4	732	25	complex	complex	NN
cord-310847-63gh2tg4	732	26	,	,	,
cord-310847-63gh2tg4	732	27	which	which	WDT
cord-310847-63gh2tg4	732	28	is	be	VBZ
cord-310847-63gh2tg4	732	29	composed	compose	VBN
cord-310847-63gh2tg4	732	30	of	of	IN
cord-310847-63gh2tg4	732	31	Cp190	Cp190	NNP
cord-310847-63gh2tg4	732	32	,	,	,
cord-310847-63gh2tg4	732	33	mod(mdg4	mod(mdg4	NNP
cord-310847-63gh2tg4	732	34	)	)	-RRB-
cord-310847-63gh2tg4	732	35	and	and	CC
cord-310847-63gh2tg4	732	36	su(Hw	su(Hw	NNP
cord-310847-63gh2tg4	732	37	)	)	-RRB-
cord-310847-63gh2tg4	732	38	and	and	CC
cord-310847-63gh2tg4	732	39	is	be	VBZ
cord-310847-63gh2tg4	732	40	required	require	VBN
cord-310847-63gh2tg4	732	41	for	for	IN
cord-310847-63gh2tg4	732	42	the	the	DT
cord-310847-63gh2tg4	732	43	function	function	NN
cord-310847-63gh2tg4	732	44	of	of	IN
cord-310847-63gh2tg4	732	45	the	the	DT
cord-310847-63gh2tg4	732	46	gypsy	gypsy	NNP
cord-310847-63gh2tg4	732	47	chromatin	chromatin	NNP
cord-310847-63gh2tg4	732	48	insulator	insulator	NN
cord-310847-63gh2tg4	732	49	and	and	CC
cord-310847-63gh2tg4	732	50	other	other	JJ
cord-310847-63gh2tg4	732	51	endogenous	endogenous	JJ
cord-310847-63gh2tg4	732	52	chromatin	chromatin	NN
cord-310847-63gh2tg4	732	53	insulators	insulator	NNS
cord-310847-63gh2tg4	732	54	organized	organize	VBN
cord-310847-63gh2tg4	732	55	by	by	IN
cord-310847-63gh2tg4	732	56	Su(Hw	Su(Hw	NNP
cord-310847-63gh2tg4	732	57	)	)	-RRB-
cord-310847-63gh2tg4	732	58	,	,	,
cord-310847-63gh2tg4	732	59	CTCF	CTCF	NNP
cord-310847-63gh2tg4	732	60	the	the	DT
cord-310847-63gh2tg4	732	61	hippocampus	hippocampus	NN
cord-310847-63gh2tg4	732	62	and	and	CC
cord-310847-63gh2tg4	732	63	cerebral	cerebral	JJ
cord-310847-63gh2tg4	732	64	cortex	cortex	NNS
cord-310847-63gh2tg4	732	65	of	of	IN
cord-310847-63gh2tg4	732	66	APP(E693Δ)-transgenic	APP(E693Δ)-transgenic	NNP
cord-310847-63gh2tg4	732	67	mice	mouse	NNS
cord-310847-63gh2tg4	732	68	that	that	WDT
cord-310847-63gh2tg4	732	69	are	be	VBP
cord-310847-63gh2tg4	732	70	used	use	VBN
cord-310847-63gh2tg4	732	71	as	as	IN
cord-310847-63gh2tg4	732	72	a	a	DT
cord-310847-63gh2tg4	732	73	model	model	NN
cord-310847-63gh2tg4	732	74	to	to	TO
cord-310847-63gh2tg4	732	75	study	study	VB
cord-310847-63gh2tg4	732	76	the	the	DT
cord-310847-63gh2tg4	732	77	pathological	pathological	JJ
cord-310847-63gh2tg4	732	78	effects	effect	NNS
cord-310847-63gh2tg4	732	79	of	of	IN
cord-310847-63gh2tg4	732	80	Aβ	Aβ	NNP
cord-310847-63gh2tg4	732	81	oligomers	oligomer	NNS
cord-310847-63gh2tg4	732	82	in	in	IN
cord-310847-63gh2tg4	732	83	Alzheimer	Alzheimer	NNP
cord-310847-63gh2tg4	732	84	's	's	POS
cord-310847-63gh2tg4	732	85	disease	disease	NN
cord-310847-63gh2tg4	732	86	.	.	.
cord-310847-63gh2tg4	733	1	228	228	CD
cord-310847-63gh2tg4	733	2	ABRA	ABRA	NNP
cord-310847-63gh2tg4	733	3	.	.	.
cord-310847-63gh2tg4	734	1	The	the	DT
cord-310847-63gh2tg4	734	2	acidic	acidic	JJ
cord-310847-63gh2tg4	734	3	-	-	HYPH
cord-310847-63gh2tg4	734	4	basic	basic	JJ
cord-310847-63gh2tg4	734	5	repeat	repeat	NN
cord-310847-63gh2tg4	734	6	antigen	antigen	NN
cord-310847-63gh2tg4	734	7	(	(	-LRB-
cord-310847-63gh2tg4	734	8	ABRA	ABRA	NNP
cord-310847-63gh2tg4	734	9	)	)	-RRB-
cord-310847-63gh2tg4	734	10	is	be	VBZ
cord-310847-63gh2tg4	734	11	a	a	DT
cord-310847-63gh2tg4	734	12	743-residues	743-residues	CD
cord-310847-63gh2tg4	734	13	-	-	HYPH
cord-310847-63gh2tg4	734	14	long	long	JJ
cord-310847-63gh2tg4	734	15	protein	protein	NN
cord-310847-63gh2tg4	734	16	found	find	VBN
cord-310847-63gh2tg4	734	17	in	in	IN
cord-310847-63gh2tg4	734	18	the	the	DT
cord-310847-63gh2tg4	734	19	vacuolar	vacuolar	JJ
cord-310847-63gh2tg4	734	20	space	space	NN
cord-310847-63gh2tg4	734	21	surrounding	surround	VBG
cord-310847-63gh2tg4	734	22	merozoites	merozoite	NNS
cord-310847-63gh2tg4	734	23	in	in	IN
cord-310847-63gh2tg4	734	24	Plasmodium	Plasmodium	NNP
cord-310847-63gh2tg4	734	25	falciparum	falciparum	NN
cord-310847-63gh2tg4	734	26	-	-	HYPH
cord-310847-63gh2tg4	734	27	infected	infect	VBN
cord-310847-63gh2tg4	734	28	erythrocytes	erythrocyte	NNS
cord-310847-63gh2tg4	734	29	,	,	,
cord-310847-63gh2tg4	734	30	being	be	VBG
cord-310847-63gh2tg4	734	31	localized	localize	VBN
cord-310847-63gh2tg4	734	32	in	in	IN
cord-310847-63gh2tg4	734	33	the	the	DT
cord-310847-63gh2tg4	734	34	parasitophorous	parasitophorous	JJ
cord-310847-63gh2tg4	734	35	vacuole	vacuole	NN
cord-310847-63gh2tg4	734	36	and	and	CC
cord-310847-63gh2tg4	734	37	associated	associate	VBN
cord-310847-63gh2tg4	734	38	with	with	IN
cord-310847-63gh2tg4	734	39	the	the	DT
cord-310847-63gh2tg4	734	40	merozoite	merozoite	NNP
cord-310847-63gh2tg4	734	41	surface	surface	NN
cord-310847-63gh2tg4	734	42	at	at	IN
cord-310847-63gh2tg4	734	43	the	the	DT
cord-310847-63gh2tg4	734	44	time	time	NN
cord-310847-63gh2tg4	734	45	of	of	IN
cord-310847-63gh2tg4	734	46	schizont	schizont	NNP
cord-310847-63gh2tg4	734	47	rupture	rupture	NN
cord-310847-63gh2tg4	734	48	.	.	.
cord-310847-63gh2tg4	735	1	229	229	CD
cord-310847-63gh2tg4	736	1	Due	due	IN
cord-310847-63gh2tg4	736	2	to	to	IN
cord-310847-63gh2tg4	736	3	its	-PRON-	PRP$
cord-310847-63gh2tg4	736	4	surface	surface	NN
cord-310847-63gh2tg4	736	5	location	location	NN
cord-310847-63gh2tg4	736	6	,	,	,
cord-310847-63gh2tg4	736	7	ABRA	ABRA	NNP
cord-310847-63gh2tg4	736	8	is	be	VBZ
cord-310847-63gh2tg4	736	9	one	one	CD
cord-310847-63gh2tg4	736	10	of	of	IN
cord-310847-63gh2tg4	736	11	the	the	DT
cord-310847-63gh2tg4	736	12	potential	potential	JJ
cord-310847-63gh2tg4	736	13	vaccine	vaccine	NN
cord-310847-63gh2tg4	736	14	candidates	candidate	NNS
cord-310847-63gh2tg4	736	15	against	against	IN
cord-310847-63gh2tg4	736	16	erythrocytic	erythrocytic	JJ
cord-310847-63gh2tg4	736	17	stages	stage	NNS
cord-310847-63gh2tg4	736	18	of	of	IN
cord-310847-63gh2tg4	736	19	malaria	malaria	NN
cord-310847-63gh2tg4	736	20	.	.	.
cord-310847-63gh2tg4	737	1	230	230	CD
cord-310847-63gh2tg4	738	1	This	this	DT
cord-310847-63gh2tg4	738	2	protein	protein	NN
cord-310847-63gh2tg4	738	3	is	be	VBZ
cord-310847-63gh2tg4	738	4	one	one	CD
cord-310847-63gh2tg4	738	5	of	of	IN
cord-310847-63gh2tg4	738	6	the	the	DT
cord-310847-63gh2tg4	738	7	antigens	antigen	NNS
cord-310847-63gh2tg4	738	8	enriched	enrich	VBN
cord-310847-63gh2tg4	738	9	in	in	IN
cord-310847-63gh2tg4	738	10	the	the	DT
cord-310847-63gh2tg4	738	11	clusters	cluster	NNS
cord-310847-63gh2tg4	738	12	of	of	IN
cord-310847-63gh2tg4	738	13	merozoites	merozoite	NNS
cord-310847-63gh2tg4	738	14	formed	form	VBN
cord-310847-63gh2tg4	738	15	with	with	IN
cord-310847-63gh2tg4	738	16	growth	growth	NN
cord-310847-63gh2tg4	738	17	inhibitory	inhibitory	JJ
cord-310847-63gh2tg4	738	18	immune	immune	JJ
cord-310847-63gh2tg4	738	19	serum	serum	NN
cord-310847-63gh2tg4	738	20	and	and	CC
cord-310847-63gh2tg4	738	21	possesses	possess	VBZ
cord-310847-63gh2tg4	738	22	chymotrypsinlike	chymotrypsinlike	JJ
cord-310847-63gh2tg4	738	23	activity	activity	NN
cord-310847-63gh2tg4	738	24	,	,	,
cord-310847-63gh2tg4	738	25	231	231	CD
cord-310847-63gh2tg4	738	26	which	which	WDT
cord-310847-63gh2tg4	738	27	can	can	MD
cord-310847-63gh2tg4	738	28	be	be	VB
cord-310847-63gh2tg4	738	29	inhibited	inhibit	VBN
cord-310847-63gh2tg4	738	30	with	with	IN
cord-310847-63gh2tg4	738	31	serine	serine	JJ
cord-310847-63gh2tg4	738	32	protease	protease	NN
cord-310847-63gh2tg4	738	33	inhibitors	inhibitor	NNS
cord-310847-63gh2tg4	738	34	such	such	JJ
cord-310847-63gh2tg4	738	35	as	as	IN
cord-310847-63gh2tg4	738	36	chymostatin	chymostatin	NN
cord-310847-63gh2tg4	738	37	and	and	CC
cord-310847-63gh2tg4	738	38	phenyl	phenyl	NN
cord-310847-63gh2tg4	738	39	methyl	methyl	NN
cord-310847-63gh2tg4	738	40	sulfonyl	sulfonyl	NNP
cord-310847-63gh2tg4	738	41	fluoride	fluoride	NN
cord-310847-63gh2tg4	738	42	(	(	-LRB-
cord-310847-63gh2tg4	738	43	PMSF	PMSF	NNP
cord-310847-63gh2tg4	738	44	)	)	-RRB-
cord-310847-63gh2tg4	738	45	.	.	.
cord-310847-63gh2tg4	739	1	232	232	CD
cord-310847-63gh2tg4	740	1	It	-PRON-	PRP
cord-310847-63gh2tg4	740	2	was	be	VBD
cord-310847-63gh2tg4	740	3	shown	show	VBN
cord-310847-63gh2tg4	740	4	that	that	IN
cord-310847-63gh2tg4	740	5	the	the	DT
cord-310847-63gh2tg4	740	6	N	n	CD
cord-310847-63gh2tg4	740	7	-	-	HYPH
cord-310847-63gh2tg4	740	8	terminal	terminal	JJ
cord-310847-63gh2tg4	740	9	half	half	NN
cord-310847-63gh2tg4	740	10	of	of	IN
cord-310847-63gh2tg4	740	11	the	the	DT
cord-310847-63gh2tg4	740	12	protein	protein	NN
cord-310847-63gh2tg4	740	13	is	be	VBZ
cord-310847-63gh2tg4	740	14	responsible	responsible	JJ
cord-310847-63gh2tg4	740	15	for	for	IN
cord-310847-63gh2tg4	740	16	the	the	DT
cord-310847-63gh2tg4	740	17	protease	protease	NN
cord-310847-63gh2tg4	740	18	activity	activity	NN
cord-310847-63gh2tg4	740	19	,	,	,
cord-310847-63gh2tg4	740	20	whereas	whereas	IN
cord-310847-63gh2tg4	740	21	the	the	DT
cord-310847-63gh2tg4	740	22	highly	highly	RB
cord-310847-63gh2tg4	740	23	charged	charge	VBN
cord-310847-63gh2tg4	740	24	C	c	NN
cord-310847-63gh2tg4	740	25	-	-	HYPH
cord-310847-63gh2tg4	740	26	terminal	terminal	NN
cord-310847-63gh2tg4	740	27	part	part	NN
cord-310847-63gh2tg4	740	28	of	of	IN
cord-310847-63gh2tg4	740	29	the	the	DT
cord-310847-63gh2tg4	740	30	protein	protein	NN
cord-310847-63gh2tg4	740	31	was	be	VBD
cord-310847-63gh2tg4	740	32	not	not	RB
cord-310847-63gh2tg4	740	33	required	require	VBN
cord-310847-63gh2tg4	740	34	for	for	IN
cord-310847-63gh2tg4	740	35	this	this	DT
cord-310847-63gh2tg4	740	36	activity	activity	NN
cord-310847-63gh2tg4	740	37	.	.	.
cord-310847-63gh2tg4	741	1	232	232	CD
cord-310847-63gh2tg4	742	1	Furthermore	furthermore	RB
cord-310847-63gh2tg4	742	2	,	,	,
cord-310847-63gh2tg4	742	3	the	the	DT
cord-310847-63gh2tg4	742	4	N	n	CD
cord-310847-63gh2tg4	742	5	-	-	HYPH
cord-310847-63gh2tg4	742	6	terminus	terminus	NN
cord-310847-63gh2tg4	742	7	contains	contain	VBZ
cord-310847-63gh2tg4	742	8	an	an	DT
cord-310847-63gh2tg4	742	9	erythrocyte	erythrocyte	NN
cord-310847-63gh2tg4	742	10	-	-	HYPH
cord-310847-63gh2tg4	742	11	binding	bind	VBG
cord-310847-63gh2tg4	742	12	domain	domain	NN
cord-310847-63gh2tg4	742	13	located	locate	VBN
cord-310847-63gh2tg4	742	14	within	within	IN
cord-310847-63gh2tg4	742	15	the	the	DT
cord-310847-63gh2tg4	742	16	cysteine	cysteine	NN
cord-310847-63gh2tg4	742	17	-	-	HYPH
cord-310847-63gh2tg4	742	18	rich	rich	JJ
cord-310847-63gh2tg4	742	19	N	n	CD
cord-310847-63gh2tg4	742	20	-	-	HYPH
cord-310847-63gh2tg4	742	21	proximal	proximal	JJ
cord-310847-63gh2tg4	742	22	region	region	NN
cord-310847-63gh2tg4	742	23	of	of	IN
cord-310847-63gh2tg4	742	24	ABRA	ABRA	NNP
cord-310847-63gh2tg4	742	25	.	.	.
cord-310847-63gh2tg4	743	1	229	229	CD
cord-310847-63gh2tg4	744	1	There	there	EX
cord-310847-63gh2tg4	744	2	are	be	VBP
cord-310847-63gh2tg4	744	3	111	111	CD
cord-310847-63gh2tg4	744	4	glutamic	glutamic	NN
cord-310847-63gh2tg4	744	5	acids	acid	NNS
cord-310847-63gh2tg4	744	6	and	and	CC
cord-310847-63gh2tg4	744	7	108	108	CD
cord-310847-63gh2tg4	744	8	lysines	lysine	NNS
cord-310847-63gh2tg4	744	9	in	in	IN
cord-310847-63gh2tg4	744	10	ABRA	ABRA	NNP
cord-310847-63gh2tg4	744	11	,	,	,
cord-310847-63gh2tg4	744	12	and	and	CC
cord-310847-63gh2tg4	744	13	in	in	IN
cord-310847-63gh2tg4	744	14	agreement	agreement	NN
cord-310847-63gh2tg4	744	15	with	with	IN
cord-310847-63gh2tg4	744	16	its	-PRON-	PRP$
cord-310847-63gh2tg4	744	17	name	name	NN
cord-310847-63gh2tg4	744	18	,	,	,
cord-310847-63gh2tg4	744	19	the	the	DT
cord-310847-63gh2tg4	744	20	amino	amino	NN
cord-310847-63gh2tg4	744	21	acid	acid	NN
cord-310847-63gh2tg4	744	22	sequence	sequence	NN
cord-310847-63gh2tg4	744	23	of	of	IN
cord-310847-63gh2tg4	744	24	this	this	DT
cord-310847-63gh2tg4	744	25	protein	protein	NN
cord-310847-63gh2tg4	744	26	is	be	VBZ
cord-310847-63gh2tg4	744	27	characterized	characterize	VBN
cord-310847-63gh2tg4	744	28	by	by	IN
cord-310847-63gh2tg4	744	29	the	the	DT
cord-310847-63gh2tg4	744	30	presence	presence	NN
cord-310847-63gh2tg4	744	31	of	of	IN
cord-310847-63gh2tg4	744	32	eight	eight	CD
cord-310847-63gh2tg4	744	33	tandem	tandem	NN
cord-310847-63gh2tg4	744	34	repeats	repeat	NNS
cord-310847-63gh2tg4	744	35	of	of	IN
cord-310847-63gh2tg4	744	36	[	[	-LRB-
cord-310847-63gh2tg4	744	37	VT]-N	VT]-N	NNP
cord-310847-63gh2tg4	744	38	-	-	HYPH
cord-310847-63gh2tg4	744	39	D-[ED]-[ED]-D	D-[ED]-[ED]-D	NNP
cord-310847-63gh2tg4	744	40	(	(	-LRB-
cord-310847-63gh2tg4	744	41	residues	residue	NNS
cord-310847-63gh2tg4	744	42	226	226	CD
cord-310847-63gh2tg4	744	43	-	-	SYM
cord-310847-63gh2tg4	744	44	273	273	CD
cord-310847-63gh2tg4	744	45	)	)	-RRB-
cord-310847-63gh2tg4	744	46	and	and	CC
cord-310847-63gh2tg4	744	47	by	by	IN
cord-310847-63gh2tg4	744	48	a	a	DT
cord-310847-63gh2tg4	744	49	lysinerich	lysinerich	NNP
cord-310847-63gh2tg4	744	50	C	C	NNP
cord-310847-63gh2tg4	744	51	-	-	HYPH
cord-310847-63gh2tg4	744	52	terminal	terminal	NN
cord-310847-63gh2tg4	744	53	region	region	NN
cord-310847-63gh2tg4	744	54	(	(	-LRB-
cord-310847-63gh2tg4	744	55	residues	residue	NNS
cord-310847-63gh2tg4	744	56	672	672	CD
cord-310847-63gh2tg4	744	57	-	-	HYPH
cord-310847-63gh2tg4	744	58	721	721	CD
cord-310847-63gh2tg4	744	59	)	)	-RRB-
cord-310847-63gh2tg4	744	60	.	.	.
cord-310847-63gh2tg4	745	1	KERP1	KERP1	NNP
cord-310847-63gh2tg4	745	2	.	.	.
cord-310847-63gh2tg4	746	1	The	the	DT
cord-310847-63gh2tg4	746	2	parasite	parasite	NN
cord-310847-63gh2tg4	746	3	Entamoeba	Entamoeba	NNP
cord-310847-63gh2tg4	746	4	histolytica	histolytica	NNP
cord-310847-63gh2tg4	746	5	that	that	WDT
cord-310847-63gh2tg4	746	6	colonizes	colonize	VBZ
cord-310847-63gh2tg4	746	7	the	the	DT
cord-310847-63gh2tg4	746	8	large	large	JJ
cord-310847-63gh2tg4	746	9	bowel	bowel	NN
cord-310847-63gh2tg4	746	10	and	and	CC
cord-310847-63gh2tg4	746	11	provokes	provoke	VBZ
cord-310847-63gh2tg4	746	12	an	an	DT
cord-310847-63gh2tg4	746	13	asymptomatic	asymptomatic	JJ
cord-310847-63gh2tg4	746	14	luminal	luminal	JJ
cord-310847-63gh2tg4	746	15	gut	gut	NN
cord-310847-63gh2tg4	746	16	infection	infection	NN
cord-310847-63gh2tg4	746	17	contains	contain	VBZ
cord-310847-63gh2tg4	746	18	a	a	DT
cord-310847-63gh2tg4	746	19	peculiar	peculiar	JJ
cord-310847-63gh2tg4	746	20	lysine	lysine	NN
cord-310847-63gh2tg4	746	21	and	and	CC
cord-310847-63gh2tg4	746	22	glutamic	glutamic	NN
cord-310847-63gh2tg4	746	23	acid	acid	NN
cord-310847-63gh2tg4	746	24	-	-	HYPH
cord-310847-63gh2tg4	746	25	rich	rich	JJ
cord-310847-63gh2tg4	746	26	protein	protein	NN
cord-310847-63gh2tg4	746	27	1	1	CD
cord-310847-63gh2tg4	746	28	(	(	-LRB-
cord-310847-63gh2tg4	746	29	KERP1	KERP1	NNP
cord-310847-63gh2tg4	746	30	)	)	-RRB-
cord-310847-63gh2tg4	746	31	,	,	,
cord-310847-63gh2tg4	746	32	which	which	WDT
cord-310847-63gh2tg4	746	33	is	be	VBZ
cord-310847-63gh2tg4	746	34	associated	associate	VBN
cord-310847-63gh2tg4	746	35	to	to	IN
cord-310847-63gh2tg4	746	36	parasite	parasite	NN
cord-310847-63gh2tg4	746	37	surface	surface	NN
cord-310847-63gh2tg4	746	38	,	,	,
cord-310847-63gh2tg4	746	39	involved	involve	VBN
cord-310847-63gh2tg4	746	40	in	in	IN
cord-310847-63gh2tg4	746	41	the	the	DT
cord-310847-63gh2tg4	746	42	parasite	parasite	NN
cord-310847-63gh2tg4	746	43	adherence	adherence	NN
cord-310847-63gh2tg4	746	44	to	to	TO
cord-310847-63gh2tg4	746	45	host	host	NN
cord-310847-63gh2tg4	746	46	cells	cell	NNS
cord-310847-63gh2tg4	746	47	and	and	CC
cord-310847-63gh2tg4	746	48	plays	play	VBZ
cord-310847-63gh2tg4	746	49	a	a	DT
cord-310847-63gh2tg4	746	50	role	role	NN
cord-310847-63gh2tg4	746	51	in	in	IN
cord-310847-63gh2tg4	746	52	the	the	DT
cord-310847-63gh2tg4	746	53	Entamoeba	Entamoeba	NNP
cord-310847-63gh2tg4	746	54	histolytica	histolytica	NNP
cord-310847-63gh2tg4	746	55	liver	liver	NN
cord-310847-63gh2tg4	746	56	abscess	abscess	NN
cord-310847-63gh2tg4	746	57	pathogenesis	pathogenesis	NN
cord-310847-63gh2tg4	746	58	.	.	.
cord-310847-63gh2tg4	747	1	233	233	CD
cord-310847-63gh2tg4	748	1	An	an	DT
cord-310847-63gh2tg4	748	2	interesting	interesting	JJ
cord-310847-63gh2tg4	748	3	feature	feature	NN
cord-310847-63gh2tg4	748	4	of	of	IN
cord-310847-63gh2tg4	748	5	KERP1	KERP1	NNP
cord-310847-63gh2tg4	748	6	(	(	-LRB-
cord-310847-63gh2tg4	748	7	184	184	CD
cord-310847-63gh2tg4	748	8	residues	residue	NNS
cord-310847-63gh2tg4	748	9	)	)	-RRB-
cord-310847-63gh2tg4	748	10	is	be	VBZ
cord-310847-63gh2tg4	748	11	a	a	DT
cord-310847-63gh2tg4	748	12	very	very	RB
cord-310847-63gh2tg4	748	13	high	high	JJ
cord-310847-63gh2tg4	748	14	content	content	NN
cord-310847-63gh2tg4	748	15	of	of	IN
cord-310847-63gh2tg4	748	16	lysines	lysine	NNS
cord-310847-63gh2tg4	748	17	(	(	-LRB-
cord-310847-63gh2tg4	748	18	25	25	CD
cord-310847-63gh2tg4	748	19	%	%	NN
cord-310847-63gh2tg4	748	20	)	)	-RRB-
cord-310847-63gh2tg4	748	21	and	and	CC
cord-310847-63gh2tg4	748	22	glutamic	glutamic	NN
cord-310847-63gh2tg4	748	23	acids	acid	NNS
cord-310847-63gh2tg4	748	24	(	(	-LRB-
cord-310847-63gh2tg4	748	25	19	19	CD
cord-310847-63gh2tg4	748	26	%	%	NN
cord-310847-63gh2tg4	748	27	)	)	-RRB-
cord-310847-63gh2tg4	748	28	.	.	.
cord-310847-63gh2tg4	749	1	Proteins	protein	NNS
cord-310847-63gh2tg4	749	2	with	with	IN
cord-310847-63gh2tg4	749	3	long	long	JJ
cord-310847-63gh2tg4	749	4	simple	simple	JJ
cord-310847-63gh2tg4	749	5	repeat	repeat	NN
cord-310847-63gh2tg4	749	6	elements	element	NNS
cord-310847-63gh2tg4	749	7	from	from	IN
cord-310847-63gh2tg4	749	8	herpesviruses	herpesviruses	NNP
cord-310847-63gh2tg4	749	9	.	.	.
cord-310847-63gh2tg4	750	1	One	one	CD
cord-310847-63gh2tg4	750	2	of	of	IN
cord-310847-63gh2tg4	750	3	the	the	DT
cord-310847-63gh2tg4	750	4	mechanisms	mechanism	NNS
cord-310847-63gh2tg4	750	5	employed	employ	VBN
cord-310847-63gh2tg4	750	6	by	by	IN
cord-310847-63gh2tg4	750	7	herpesviruses	herpesviruse	NNS
cord-310847-63gh2tg4	750	8	to	to	TO
cord-310847-63gh2tg4	750	9	evade	evade	VB
cord-310847-63gh2tg4	750	10	the	the	DT
cord-310847-63gh2tg4	750	11	immune	immune	JJ
cord-310847-63gh2tg4	750	12	response	response	NN
cord-310847-63gh2tg4	750	13	,	,	,
cord-310847-63gh2tg4	750	14	allowing	allow	VBG
cord-310847-63gh2tg4	750	15	them	-PRON-	PRP
cord-310847-63gh2tg4	750	16	to	to	TO
cord-310847-63gh2tg4	750	17	persist	persist	VB
cord-310847-63gh2tg4	750	18	life	life	NN
cord-310847-63gh2tg4	750	19	-	-	HYPH
cord-310847-63gh2tg4	750	20	long	long	RB
cord-310847-63gh2tg4	750	21	in	in	IN
cord-310847-63gh2tg4	750	22	their	-PRON-	PRP$
cord-310847-63gh2tg4	750	23	hosts	host	NNS
cord-310847-63gh2tg4	750	24	,	,	,
cord-310847-63gh2tg4	750	25	relies	rely	VBZ
cord-310847-63gh2tg4	750	26	on	on	IN
cord-310847-63gh2tg4	750	27	the	the	DT
cord-310847-63gh2tg4	750	28	use	use	NN
cord-310847-63gh2tg4	750	29	of	of	IN
cord-310847-63gh2tg4	750	30	specific	specific	JJ
cord-310847-63gh2tg4	750	31	proteins	protein	NNS
cord-310847-63gh2tg4	750	32	that	that	WDT
cord-310847-63gh2tg4	750	33	function	function	VBP
cord-310847-63gh2tg4	750	34	as	as	IN
cord-310847-63gh2tg4	750	35	cis	cis	NNP
cord-310847-63gh2tg4	750	36	-	-	HYPH
cord-310847-63gh2tg4	750	37	acting	act	VBG
cord-310847-63gh2tg4	750	38	inhibitors	inhibitor	NNS
cord-310847-63gh2tg4	750	39	of	of	IN
cord-310847-63gh2tg4	750	40	antigen	antigen	NN
cord-310847-63gh2tg4	750	41	presentation	presentation	NN
cord-310847-63gh2tg4	750	42	.	.	.
cord-310847-63gh2tg4	751	1	234	234	CD
cord-310847-63gh2tg4	752	1	Among	among	IN
cord-310847-63gh2tg4	752	2	these	these	DT
cord-310847-63gh2tg4	752	3	inhibitors	inhibitor	NNS
cord-310847-63gh2tg4	752	4	are	be	VBP
cord-310847-63gh2tg4	752	5	the	the	DT
cord-310847-63gh2tg4	752	6	nuclear	nuclear	JJ
cord-310847-63gh2tg4	752	7	antigen	antigen	NN
cord-310847-63gh2tg4	752	8	1	1	CD
cord-310847-63gh2tg4	752	9	(	(	-LRB-
cord-310847-63gh2tg4	752	10	EBNA1	EBNA1	NNS
cord-310847-63gh2tg4	752	11	)	)	-RRB-
cord-310847-63gh2tg4	753	1	and	and	CC
cord-310847-63gh2tg4	753	2	pGZr	pgzr	RB
cord-310847-63gh2tg4	753	3	in	in	IN
cord-310847-63gh2tg4	753	4	the	the	DT
cord-310847-63gh2tg4	753	5	Epstein	Epstein	NNP
cord-310847-63gh2tg4	753	6	-	-	HYPH
cord-310847-63gh2tg4	753	7	Barr	Barr	NNP
cord-310847-63gh2tg4	753	8	virus	virus	NN
cord-310847-63gh2tg4	753	9	(	(	-LRB-
cord-310847-63gh2tg4	753	10	EBV	EBV	NNP
cord-310847-63gh2tg4	753	11	)	)	-RRB-
cord-310847-63gh2tg4	753	12	and	and	CC
cord-310847-63gh2tg4	753	13	the	the	DT
cord-310847-63gh2tg4	753	14	latency	latency	NN
cord-310847-63gh2tg4	753	15	-	-	HYPH
cord-310847-63gh2tg4	753	16	associated	associate	VBN
cord-310847-63gh2tg4	753	17	nuclear	nuclear	JJ
cord-310847-63gh2tg4	753	18	antigen	antigen	NN
cord-310847-63gh2tg4	753	19	1	1	CD
cord-310847-63gh2tg4	753	20	(	(	-LRB-
cord-310847-63gh2tg4	753	21	LANA1	LANA1	NNP
cord-310847-63gh2tg4	753	22	)	)	-RRB-
cord-310847-63gh2tg4	753	23	of	of	IN
cord-310847-63gh2tg4	753	24	the	the	DT
cord-310847-63gh2tg4	753	25	Kaposi	Kaposi	NNP
cord-310847-63gh2tg4	753	26	sarcoma	sarcoma	NN
cord-310847-63gh2tg4	753	27	herpesvirus	herpesvirus	NN
cord-310847-63gh2tg4	753	28	.	.	.
cord-310847-63gh2tg4	754	1	234	234	CD
cord-310847-63gh2tg4	755	1	The	the	DT
cord-310847-63gh2tg4	755	2	common	common	JJ
cord-310847-63gh2tg4	755	3	feature	feature	NN
cord-310847-63gh2tg4	755	4	of	of	IN
cord-310847-63gh2tg4	755	5	all	all	PDT
cord-310847-63gh2tg4	755	6	these	these	DT
cord-310847-63gh2tg4	755	7	proteins	protein	NNS
cord-310847-63gh2tg4	755	8	is	be	VBZ
cord-310847-63gh2tg4	755	9	the	the	DT
cord-310847-63gh2tg4	755	10	presence	presence	NN
cord-310847-63gh2tg4	755	11	of	of	IN
cord-310847-63gh2tg4	755	12	long	long	JJ
cord-310847-63gh2tg4	755	13	simple	simple	JJ
cord-310847-63gh2tg4	755	14	repeat	repeat	NN
cord-310847-63gh2tg4	755	15	elements	element	NNS
cord-310847-63gh2tg4	755	16	in	in	IN
cord-310847-63gh2tg4	755	17	their	-PRON-	PRP$
cord-310847-63gh2tg4	755	18	amino	amino	NN
cord-310847-63gh2tg4	755	19	acid	acid	NN
cord-310847-63gh2tg4	755	20	sequences	sequence	NNS
cord-310847-63gh2tg4	755	21	.	.	.
cord-310847-63gh2tg4	756	1	For	for	IN
cord-310847-63gh2tg4	756	2	example	example	NN
cord-310847-63gh2tg4	756	3	,	,	,
cord-310847-63gh2tg4	756	4	pGZr	pGZr	NNP
cord-310847-63gh2tg4	756	5	is	be	VBZ
cord-310847-63gh2tg4	756	6	a	a	DT
cord-310847-63gh2tg4	756	7	230	230	CD
cord-310847-63gh2tg4	756	8	amino	amino	NNS
cord-310847-63gh2tg4	756	9	-	-	HYPH
cord-310847-63gh2tg4	756	10	acids	acid	NNS
cord-310847-63gh2tg4	756	11	long	long	JJ
cord-310847-63gh2tg4	756	12	glycine	glycine	NN
cord-310847-63gh2tg4	756	13	,	,	,
cord-310847-63gh2tg4	756	14	glutamine	glutamine	NN
cord-310847-63gh2tg4	756	15	,	,	,
cord-310847-63gh2tg4	756	16	and	and	CC
cord-310847-63gh2tg4	756	17	glutamic	glutamic	NN
cord-310847-63gh2tg4	756	18	acid	acid	NN
cord-310847-63gh2tg4	756	19	-	-	HYPH
cord-310847-63gh2tg4	756	20	rich	rich	JJ
cord-310847-63gh2tg4	756	21	repeat	repeat	NN
cord-310847-63gh2tg4	756	22	(	(	-LRB-
cord-310847-63gh2tg4	756	23	"	"	``
cord-310847-63gh2tg4	756	24	GZ	gz	NN
cord-310847-63gh2tg4	756	25	"	"	''
cord-310847-63gh2tg4	756	26	repeat	repeat	NN
cord-310847-63gh2tg4	756	27	)	)	-RRB-
cord-310847-63gh2tg4	756	28	protein	protein	NN
cord-310847-63gh2tg4	756	29	that	that	WDT
cord-310847-63gh2tg4	756	30	which	which	WDT
cord-310847-63gh2tg4	756	31	is	be	VBZ
cord-310847-63gh2tg4	756	32	encoded	encode	VBN
cord-310847-63gh2tg4	756	33	by	by	IN
cord-310847-63gh2tg4	756	34	a	a	DT
cord-310847-63gh2tg4	756	35	large	large	JJ
cord-310847-63gh2tg4	756	36	nested	nested	JJ
cord-310847-63gh2tg4	756	37	open	open	JJ
cord-310847-63gh2tg4	756	38	reading	reading	NN
cord-310847-63gh2tg4	756	39	frame	frame	NN
cord-310847-63gh2tg4	756	40	located	locate	VBN
cord-310847-63gh2tg4	756	41	in	in	IN
cord-310847-63gh2tg4	756	42	the	the	DT
cord-310847-63gh2tg4	756	43	EBNA1	EBNA1	NNS
cord-310847-63gh2tg4	757	1	mRNA	mRNA	NNP
cord-310847-63gh2tg4	758	1	and	and	CC
cord-310847-63gh2tg4	758	2	is	be	VBZ
cord-310847-63gh2tg4	758	3	highly	highly	RB
cord-310847-63gh2tg4	758	4	similar	similar	JJ
cord-310847-63gh2tg4	758	5	(	(	-LRB-
cord-310847-63gh2tg4	758	6	65	65	CD
cord-310847-63gh2tg4	758	7	%	%	NN
cord-310847-63gh2tg4	758	8	amino	amino	NN
cord-310847-63gh2tg4	758	9	-	-	HYPH
cord-310847-63gh2tg4	758	10	acid	acid	NN
cord-310847-63gh2tg4	758	11	identity	identity	NN
cord-310847-63gh2tg4	758	12	)	)	-RRB-
cord-310847-63gh2tg4	758	13	to	to	IN
cord-310847-63gh2tg4	758	14	the	the	DT
cord-310847-63gh2tg4	758	15	acidic	acidic	JJ
cord-310847-63gh2tg4	758	16	repeat	repeat	NN
cord-310847-63gh2tg4	758	17	of	of	IN
cord-310847-63gh2tg4	758	18	LANA1	LANA1	NNS
cord-310847-63gh2tg4	758	19	.	.	.
cord-310847-63gh2tg4	759	1	234	234	CD
cord-310847-63gh2tg4	759	2	Latent	Latent	NNP
cord-310847-63gh2tg4	759	3	nuclear	nuclear	JJ
cord-310847-63gh2tg4	759	4	antigen	antigen	NN
cord-310847-63gh2tg4	759	5	of	of	IN
cord-310847-63gh2tg4	759	6	human	human	JJ
cord-310847-63gh2tg4	759	7	herpesvirus	herpesvirus	NN
cord-310847-63gh2tg4	759	8	8	8	CD
cord-310847-63gh2tg4	759	9	(	(	-LRB-
cord-310847-63gh2tg4	759	10	HHV-8	HHV-8	NNP
cord-310847-63gh2tg4	759	11	)	)	-RRB-
cord-310847-63gh2tg4	760	1	(	(	-LRB-
cord-310847-63gh2tg4	760	2	Kaposi	Kaposi	NNP
cord-310847-63gh2tg4	760	3	's	's	POS
cord-310847-63gh2tg4	760	4	sarcoma	sarcoma	NN
cord-310847-63gh2tg4	760	5	-	-	HYPH
cord-310847-63gh2tg4	760	6	associated	associate	VBN
cord-310847-63gh2tg4	760	7	herpesvirus	herpesvirus	NN
cord-310847-63gh2tg4	760	8	)	)	-RRB-
cord-310847-63gh2tg4	760	9	is	be	VBZ
cord-310847-63gh2tg4	760	10	a	a	DT
cord-310847-63gh2tg4	760	11	large	large	JJ
cord-310847-63gh2tg4	760	12	(	(	-LRB-
cord-310847-63gh2tg4	760	13	1,036	1,036	CD
cord-310847-63gh2tg4	760	14	residues	residue	NNS
cord-310847-63gh2tg4	760	15	)	)	-RRB-
cord-310847-63gh2tg4	760	16	highly	highly	RB
cord-310847-63gh2tg4	760	17	acidic	acidic	JJ
cord-310847-63gh2tg4	760	18	protein	protein	NN
cord-310847-63gh2tg4	760	19	(	(	-LRB-
cord-310847-63gh2tg4	760	20	pI	pI	NNP
cord-310847-63gh2tg4	760	21	3.81	3.81	CD
cord-310847-63gh2tg4	760	22	)	)	-RRB-
cord-310847-63gh2tg4	760	23	that	that	WDT
cord-310847-63gh2tg4	760	24	contains	contain	VBZ
cord-310847-63gh2tg4	760	25	237	237	CD
cord-310847-63gh2tg4	760	26	glutamic	glutamic	NN
cord-310847-63gh2tg4	760	27	acids	acid	NNS
cord-310847-63gh2tg4	760	28	,	,	,
cord-310847-63gh2tg4	760	29	179	179	CD
cord-310847-63gh2tg4	760	30	glutamines	glutamine	NNS
cord-310847-63gh2tg4	760	31	,	,	,
cord-310847-63gh2tg4	760	32	114	114	CD
cord-310847-63gh2tg4	760	33	prolines	proline	NNS
cord-310847-63gh2tg4	760	34	and	and	CC
cord-310847-63gh2tg4	760	35	90	90	CD
cord-310847-63gh2tg4	760	36	aspartic	aspartic	JJ
cord-310847-63gh2tg4	760	37	acids	acid	NNS
cord-310847-63gh2tg4	760	38	.	.	.
cord-310847-63gh2tg4	761	1	In	in	IN
cord-310847-63gh2tg4	761	2	Herpesvirus	Herpesvirus	NNP
cord-310847-63gh2tg4	761	3	saimiri	saimiri	NNP
cord-310847-63gh2tg4	761	4	(	(	-LRB-
cord-310847-63gh2tg4	761	5	HVS	HVS	NNP
cord-310847-63gh2tg4	761	6	)	)	-RRB-
cord-310847-63gh2tg4	761	7	that	that	WDT
cord-310847-63gh2tg4	761	8	infects	infect	VBZ
cord-310847-63gh2tg4	761	9	squirrel	squirrel	NN
cord-310847-63gh2tg4	761	10	monkeys	monkey	NNS
cord-310847-63gh2tg4	761	11	,	,	,
cord-310847-63gh2tg4	761	12	the	the	DT
cord-310847-63gh2tg4	761	13	functional	functional	JJ
cord-310847-63gh2tg4	761	14	homolog	homolog	NN
cord-310847-63gh2tg4	761	15	of	of	IN
cord-310847-63gh2tg4	761	16	Epstein	Epstein	NNP
cord-310847-63gh2tg4	761	17	-	-	HYPH
cord-310847-63gh2tg4	761	18	Barr	Barr	NNP
cord-310847-63gh2tg4	761	19	virus	virus	NN
cord-310847-63gh2tg4	761	20	EBNA1	EBNA1	NNS
cord-310847-63gh2tg4	761	21	and	and	CC
cord-310847-63gh2tg4	761	22	Kaposi	Kaposi	NNP
cord-310847-63gh2tg4	761	23	's	's	POS
cord-310847-63gh2tg4	761	24	sarcoma	sarcoma	NN
cord-310847-63gh2tg4	761	25	-	-	HYPH
cord-310847-63gh2tg4	761	26	associated	associate	VBN
cord-310847-63gh2tg4	761	27	herpesvirus	herpesvirus	NN
cord-310847-63gh2tg4	761	28	LANA1	LANA1	NNS
cord-310847-63gh2tg4	761	29	proteins	protein	NNS
cord-310847-63gh2tg4	761	30	is	be	VBZ
cord-310847-63gh2tg4	761	31	the	the	DT
cord-310847-63gh2tg4	761	32	501	501	CD
cord-310847-63gh2tg4	761	33	residues	residue	NNS
cord-310847-63gh2tg4	761	34	-	-	HYPH
cord-310847-63gh2tg4	761	35	long	long	JJ
cord-310847-63gh2tg4	761	36	product	product	NN
cord-310847-63gh2tg4	761	37	of	of	IN
cord-310847-63gh2tg4	761	38	the	the	DT
cord-310847-63gh2tg4	761	39	open	open	JJ
cord-310847-63gh2tg4	761	40	reading	reading	NN
cord-310847-63gh2tg4	761	41	frame	frame	NN
cord-310847-63gh2tg4	761	42	73	73	CD
cord-310847-63gh2tg4	761	43	known	know	VBN
cord-310847-63gh2tg4	761	44	as	as	IN
cord-310847-63gh2tg4	761	45	ORF73	ORF73	NNP
cord-310847-63gh2tg4	761	46	or	or	CC
cord-310847-63gh2tg4	761	47	latency	latency	NNP
cord-310847-63gh2tg4	761	48	associated	associate	VBD
cord-310847-63gh2tg4	761	49	nuclear	nuclear	JJ
cord-310847-63gh2tg4	761	50	antigen	antigen	NN
cord-310847-63gh2tg4	761	51	.	.	.
cord-310847-63gh2tg4	762	1	235	235	CD
cord-310847-63gh2tg4	762	2	ORF73	ORF73	NNP
cord-310847-63gh2tg4	762	3	contains	contain	VBZ
cord-310847-63gh2tg4	762	4	a	a	DT
cord-310847-63gh2tg4	762	5	repeat	repeat	NN
cord-310847-63gh2tg4	762	6	domain	domain	NN
cord-310847-63gh2tg4	762	7	composed	compose	VBN
cord-310847-63gh2tg4	762	8	of	of	IN
cord-310847-63gh2tg4	762	9	a	a	DT
cord-310847-63gh2tg4	762	10	glutamic	glutamic	NN
cord-310847-63gh2tg4	762	11	acid	acid	NN
cord-310847-63gh2tg4	762	12	and	and	CC
cord-310847-63gh2tg4	762	13	glycine	glycine	NN
cord-310847-63gh2tg4	762	14	repeat	repeat	NN
cord-310847-63gh2tg4	762	15	mutation	mutation	NN
cord-310847-63gh2tg4	762	16	affects	affect	VBZ
cord-310847-63gh2tg4	762	17	the	the	DT
cord-310847-63gh2tg4	762	18	ability	ability	NN
cord-310847-63gh2tg4	762	19	of	of	IN
cord-310847-63gh2tg4	762	20	HLA	HLA	NNP
cord-310847-63gh2tg4	762	21	-	-	HYPH
cord-310847-63gh2tg4	762	22	DPB1	DPB1	NNP
cord-310847-63gh2tg4	762	23	to	to	TO
cord-310847-63gh2tg4	762	24	present	present	VB
cord-310847-63gh2tg4	762	25	beryllium	beryllium	NN
cord-310847-63gh2tg4	762	26	to	to	IN
cord-310847-63gh2tg4	762	27	pathogenic	pathogenic	JJ
cord-310847-63gh2tg4	762	28	CD4	CD4	NNP
cord-310847-63gh2tg4	762	29	+	+	CC
cord-310847-63gh2tg4	762	30	T	t	NN
cord-310847-63gh2tg4	762	31	cells	cell	NNS
cord-310847-63gh2tg4	762	32	.	.	.
cord-310847-63gh2tg4	763	1	242	242	CD
cord-310847-63gh2tg4	763	2	Sickle	Sickle	NNP
cord-310847-63gh2tg4	763	3	cell	cell	NN
cord-310847-63gh2tg4	763	4	anemia	anemia	NN
cord-310847-63gh2tg4	763	5	and	and	CC
cord-310847-63gh2tg4	763	6	Glu6Val	Glu6Val	NNP
cord-310847-63gh2tg4	763	7	mutation	mutation	NN
cord-310847-63gh2tg4	763	8	in	in	IN
cord-310847-63gh2tg4	763	9	hemoglobin	hemoglobin	NN
cord-310847-63gh2tg4	763	10	.	.	.
cord-310847-63gh2tg4	764	1	Sicklecell	Sicklecell	NNP
cord-310847-63gh2tg4	764	2	(	(	-LRB-
cord-310847-63gh2tg4	764	3	SCA	SCA	NNP
cord-310847-63gh2tg4	764	4	)	)	-RRB-
cord-310847-63gh2tg4	764	5	or	or	CC
cord-310847-63gh2tg4	764	6	drepanocytosis	drepanocytosis	NN
cord-310847-63gh2tg4	764	7	is	be	VBZ
cord-310847-63gh2tg4	764	8	an	an	DT
cord-310847-63gh2tg4	764	9	autosomal	autosomal	JJ
cord-310847-63gh2tg4	764	10	recessive	recessive	JJ
cord-310847-63gh2tg4	764	11	genetic	genetic	JJ
cord-310847-63gh2tg4	764	12	blood	blood	NN
cord-310847-63gh2tg4	764	13	disease	disease	NN
cord-310847-63gh2tg4	764	14	with	with	IN
cord-310847-63gh2tg4	764	15	over	over	IN
cord-310847-63gh2tg4	764	16	-	-	HYPH
cord-310847-63gh2tg4	764	17	dominance	dominance	NN
cord-310847-63gh2tg4	764	18	,	,	,
cord-310847-63gh2tg4	764	19	characterized	characterize	VBN
cord-310847-63gh2tg4	764	20	by	by	IN
cord-310847-63gh2tg4	764	21	red	red	JJ
cord-310847-63gh2tg4	764	22	blood	blood	NN
cord-310847-63gh2tg4	764	23	cells	cell	NNS
cord-310847-63gh2tg4	764	24	that	that	WDT
cord-310847-63gh2tg4	764	25	assume	assume	VBP
cord-310847-63gh2tg4	764	26	an	an	DT
cord-310847-63gh2tg4	764	27	abnormal	abnormal	JJ
cord-310847-63gh2tg4	764	28	,	,	,
cord-310847-63gh2tg4	764	29	rigid	rigid	JJ
cord-310847-63gh2tg4	764	30	,	,	,
cord-310847-63gh2tg4	764	31	sickle	sickle	NN
cord-310847-63gh2tg4	764	32	shape	shape	NN
cord-310847-63gh2tg4	764	33	.	.	.
cord-310847-63gh2tg4	765	1	The	the	DT
cord-310847-63gh2tg4	765	2	disease	disease	NN
cord-310847-63gh2tg4	765	3	is	be	VBZ
cord-310847-63gh2tg4	765	4	caused	cause	VBN
cord-310847-63gh2tg4	765	5	by	by	IN
cord-310847-63gh2tg4	765	6	a	a	DT
cord-310847-63gh2tg4	765	7	single	single	JJ
cord-310847-63gh2tg4	765	8	point	point	NN
cord-310847-63gh2tg4	765	9	mutation	mutation	NN
cord-310847-63gh2tg4	765	10	in	in	IN
cord-310847-63gh2tg4	765	11	the	the	DT
cord-310847-63gh2tg4	765	12	β	β	NN
cord-310847-63gh2tg4	765	13	-	-	HYPH
cord-310847-63gh2tg4	765	14	globin	globin	NN
cord-310847-63gh2tg4	765	15	chain	chain	NN
cord-310847-63gh2tg4	765	16	of	of	IN
cord-310847-63gh2tg4	765	17	hemoglobin	hemoglobin	NN
cord-310847-63gh2tg4	765	18	where	where	WRB
cord-310847-63gh2tg4	765	19	the	the	DT
cord-310847-63gh2tg4	765	20	hydrophilic	hydrophilic	JJ
cord-310847-63gh2tg4	765	21	and	and	CC
cord-310847-63gh2tg4	765	22	negatively	negatively	RB
cord-310847-63gh2tg4	765	23	charged	charge	VBN
cord-310847-63gh2tg4	765	24	amino	amino	NN
cord-310847-63gh2tg4	765	25	acid	acid	NN
cord-310847-63gh2tg4	765	26	glutamic	glutamic	NN
cord-310847-63gh2tg4	765	27	acid	acid	NN
cord-310847-63gh2tg4	765	28	is	be	VBZ
cord-310847-63gh2tg4	765	29	replaced	replace	VBN
cord-310847-63gh2tg4	765	30	by	by	IN
cord-310847-63gh2tg4	765	31	the	the	DT
cord-310847-63gh2tg4	765	32	hydrophobic	hydrophobic	JJ
cord-310847-63gh2tg4	765	33	amino	amino	NN
cord-310847-63gh2tg4	765	34	acid	acid	NN
cord-310847-63gh2tg4	765	35	valine	valine	NN
cord-310847-63gh2tg4	765	36	at	at	IN
cord-310847-63gh2tg4	765	37	the	the	DT
cord-310847-63gh2tg4	765	38	sixth	sixth	JJ
cord-310847-63gh2tg4	765	39	position	position	NN
cord-310847-63gh2tg4	765	40	.	.	.
cord-310847-63gh2tg4	766	1	As	as	IN
cord-310847-63gh2tg4	766	2	a	a	DT
cord-310847-63gh2tg4	766	3	result	result	NN
cord-310847-63gh2tg4	766	4	of	of	IN
cord-310847-63gh2tg4	766	5	this	this	DT
cord-310847-63gh2tg4	766	6	substitution	substitution	NN
cord-310847-63gh2tg4	766	7	,	,	,
cord-310847-63gh2tg4	766	8	sickle	sickle	NN
cord-310847-63gh2tg4	766	9	hemoglobin	hemoglobin	NN
cord-310847-63gh2tg4	766	10	polymerizes	polymerize	VBZ
cord-310847-63gh2tg4	766	11	inside	inside	IN
cord-310847-63gh2tg4	766	12	the	the	DT
cord-310847-63gh2tg4	766	13	affected	affected	JJ
cord-310847-63gh2tg4	766	14	erythrocytes	erythrocyte	NNS
cord-310847-63gh2tg4	766	15	.	.	.
cord-310847-63gh2tg4	767	1	It	-PRON-	PRP
cord-310847-63gh2tg4	767	2	was	be	VBD
cord-310847-63gh2tg4	767	3	pointed	point	VBN
cord-310847-63gh2tg4	767	4	out	out	RP
cord-310847-63gh2tg4	767	5	that	that	IN
cord-310847-63gh2tg4	767	6	such	such	JJ
cord-310847-63gh2tg4	767	7	sickle	sickle	NN
cord-310847-63gh2tg4	767	8	hemoglobin	hemoglobin	NN
cord-310847-63gh2tg4	767	9	polymerization	polymerization	NN
cord-310847-63gh2tg4	767	10	occurs	occur	VBZ
cord-310847-63gh2tg4	767	11	by	by	IN
cord-310847-63gh2tg4	767	12	homogeneous	homogeneous	JJ
cord-310847-63gh2tg4	767	13	and	and	CC
cord-310847-63gh2tg4	767	14	heterogeneous	heterogeneous	JJ
cord-310847-63gh2tg4	767	15	nucleation	nucleation	NN
cord-310847-63gh2tg4	767	16	mechanisms	mechanism	NNS
cord-310847-63gh2tg4	767	17	,	,	,
cord-310847-63gh2tg4	767	18	which	which	WDT
cord-310847-63gh2tg4	767	19	are	be	VBP
cord-310847-63gh2tg4	767	20	both	both	DT
cord-310847-63gh2tg4	767	21	highly	highly	RB
cord-310847-63gh2tg4	767	22	sensitive	sensitive	JJ
cord-310847-63gh2tg4	767	23	to	to	IN
cord-310847-63gh2tg4	767	24	macromolecular	macromolecular	JJ
cord-310847-63gh2tg4	767	25	crowding	crowding	NN
cord-310847-63gh2tg4	767	26	.	.	.
cord-310847-63gh2tg4	768	1	243	243	CD
cord-310847-63gh2tg4	769	1	In	in	IN
cord-310847-63gh2tg4	769	2	fact	fact	NN
cord-310847-63gh2tg4	769	3	,	,	,
cord-310847-63gh2tg4	769	4	the	the	DT
cord-310847-63gh2tg4	769	5	rates	rate	NNS
cord-310847-63gh2tg4	769	6	of	of	IN
cord-310847-63gh2tg4	769	7	homogeneous	homogeneous	JJ
cord-310847-63gh2tg4	769	8	nucleation	nucleation	NN
cord-310847-63gh2tg4	769	9	were	be	VBD
cord-310847-63gh2tg4	769	10	shown	show	VBN
cord-310847-63gh2tg4	769	11	to	to	TO
cord-310847-63gh2tg4	769	12	be	be	VB
cord-310847-63gh2tg4	769	13	enhanced	enhance	VBN
cord-310847-63gh2tg4	769	14	by	by	IN
cord-310847-63gh2tg4	769	15	10	10	CD
cord-310847-63gh2tg4	769	16	10	10	CD
cord-310847-63gh2tg4	769	17	when	when	WRB
cord-310847-63gh2tg4	769	18	the	the	DT
cord-310847-63gh2tg4	769	19	initial	initial	JJ
cord-310847-63gh2tg4	769	20	concentration	concentration	NN
cord-310847-63gh2tg4	769	21	was	be	VBD
cord-310847-63gh2tg4	769	22	augmented	augment	VBN
cord-310847-63gh2tg4	769	23	by	by	IN
cord-310847-63gh2tg4	769	24	50	50	CD
cord-310847-63gh2tg4	769	25	%	%	NN
cord-310847-63gh2tg4	769	26	nonpolymerizing	nonpolymerize	VBG
cord-310847-63gh2tg4	769	27	hemoglobin	hemoglobin	NN
cord-310847-63gh2tg4	769	28	.	.	.
cord-310847-63gh2tg4	770	1	243	243	CD
cord-310847-63gh2tg4	770	2	Retinitis	retinitis	NN
cord-310847-63gh2tg4	770	3	pigmentosa	pigmentosa	NN
cord-310847-63gh2tg4	770	4	and	and	CC
cord-310847-63gh2tg4	770	5	mutations	mutation	NNS
cord-310847-63gh2tg4	770	6	in	in	IN
cord-310847-63gh2tg4	770	7	a	a	DT
cord-310847-63gh2tg4	770	8	Glu	Glu	NNP
cord-310847-63gh2tg4	770	9	-	-	HYPH
cord-310847-63gh2tg4	770	10	rich	rich	JJ
cord-310847-63gh2tg4	770	11	domain	domain	NN
cord-310847-63gh2tg4	770	12	of	of	IN
cord-310847-63gh2tg4	770	13	RPGR	RPGR	NNP
cord-310847-63gh2tg4	770	14	.	.	.
cord-310847-63gh2tg4	771	1	Retinitis	retinitis	NN
cord-310847-63gh2tg4	771	2	pigmentosa	pigmentosa	NN
cord-310847-63gh2tg4	771	3	(	(	-LRB-
cord-310847-63gh2tg4	771	4	RP	RP	NNP
cord-310847-63gh2tg4	771	5	)	)	-RRB-
cord-310847-63gh2tg4	771	6	is	be	VBZ
cord-310847-63gh2tg4	771	7	an	an	DT
cord-310847-63gh2tg4	771	8	inherited	inherit	VBN
cord-310847-63gh2tg4	771	9	,	,	,
cord-310847-63gh2tg4	771	10	degenerative	degenerative	JJ
cord-310847-63gh2tg4	771	11	eye	eye	NN
cord-310847-63gh2tg4	771	12	disease	disease	NN
cord-310847-63gh2tg4	771	13	associated	associate	VBN
cord-310847-63gh2tg4	771	14	with	with	IN
cord-310847-63gh2tg4	771	15	the	the	DT
cord-310847-63gh2tg4	771	16	progressive	progressive	JJ
cord-310847-63gh2tg4	771	17	loss	loss	NN
cord-310847-63gh2tg4	771	18	of	of	IN
cord-310847-63gh2tg4	771	19	photoreceptor	photoreceptor	NN
cord-310847-63gh2tg4	771	20	genes	gene	NNS
cord-310847-63gh2tg4	771	21	that	that	WDT
cord-310847-63gh2tg4	771	22	causes	cause	VBZ
cord-310847-63gh2tg4	771	23	severe	severe	JJ
cord-310847-63gh2tg4	771	24	vision	vision	NN
cord-310847-63gh2tg4	771	25	impairment	impairment	NN
cord-310847-63gh2tg4	771	26	and	and	CC
cord-310847-63gh2tg4	771	27	often	often	RB
cord-310847-63gh2tg4	771	28	blindness	blindness	VBP
cord-310847-63gh2tg4	771	29	.	.	.
cord-310847-63gh2tg4	772	1	244	244	CD
cord-310847-63gh2tg4	773	1	Among	among	IN
cord-310847-63gh2tg4	773	2	other	other	JJ
cord-310847-63gh2tg4	773	3	factors	factor	NNS
cord-310847-63gh2tg4	773	4	,	,	,
cord-310847-63gh2tg4	773	5	RP	RP	NNP
cord-310847-63gh2tg4	773	6	is	be	VBZ
cord-310847-63gh2tg4	773	7	caused	cause	VBN
cord-310847-63gh2tg4	773	8	by	by	IN
cord-310847-63gh2tg4	773	9	mutations	mutation	NNS
cord-310847-63gh2tg4	773	10	in	in	IN
cord-310847-63gh2tg4	773	11	the	the	DT
cord-310847-63gh2tg4	773	12	retinitis	retinitis	NN
cord-310847-63gh2tg4	773	13	pigmentosa	pigmentosa	NN
cord-310847-63gh2tg4	773	14	GTPase	GTPase	NNP
cord-310847-63gh2tg4	773	15	regulator	regulator	NN
cord-310847-63gh2tg4	773	16	(	(	-LRB-
cord-310847-63gh2tg4	773	17	RPGR	RPGR	NNP
cord-310847-63gh2tg4	773	18	)	)	-RRB-
cord-310847-63gh2tg4	773	19	gene	gene	NN
cord-310847-63gh2tg4	773	20	which	which	WDT
cord-310847-63gh2tg4	773	21	accounts	account	VBZ
cord-310847-63gh2tg4	773	22	for	for	IN
cord-310847-63gh2tg4	773	23	15	15	CD
cord-310847-63gh2tg4	773	24	-	-	SYM
cord-310847-63gh2tg4	773	25	20	20	CD
cord-310847-63gh2tg4	773	26	%	%	NN
cord-310847-63gh2tg4	773	27	of	of	IN
cord-310847-63gh2tg4	773	28	RP	rp	NN
cord-310847-63gh2tg4	773	29	cases	case	NNS
cord-310847-63gh2tg4	773	30	in	in	IN
cord-310847-63gh2tg4	773	31	Caucasians	Caucasians	NNPS
cord-310847-63gh2tg4	773	32	.	.	.
cord-310847-63gh2tg4	774	1	245	245	CD
cord-310847-63gh2tg4	774	2	Genetic	genetic	JJ
cord-310847-63gh2tg4	774	3	analysis	analysis	NN
cord-310847-63gh2tg4	774	4	revealed	reveal	VBD
cord-310847-63gh2tg4	774	5	that	that	DT
cord-310847-63gh2tg4	774	6	of	of	IN
cord-310847-63gh2tg4	774	7	240	240	CD
cord-310847-63gh2tg4	774	8	RPGR	RPGR	NNP
cord-310847-63gh2tg4	774	9	mutations	mutation	NNS
cord-310847-63gh2tg4	774	10	95	95	CD
cord-310847-63gh2tg4	774	11	%	%	NN
cord-310847-63gh2tg4	774	12	are	be	VBP
cord-310847-63gh2tg4	774	13	associated	associate	VBN
cord-310847-63gh2tg4	774	14	with	with	IN
cord-310847-63gh2tg4	774	15	X	x	NN
cord-310847-63gh2tg4	774	16	-	-	HYPH
cord-310847-63gh2tg4	774	17	linked	link	VBN
cord-310847-63gh2tg4	774	18	retinitis	retinitis	NN
cord-310847-63gh2tg4	774	19	pigmentosa	pigmentosa	NN
cord-310847-63gh2tg4	774	20	(	(	-LRB-
cord-310847-63gh2tg4	774	21	XLRP	XLRP	NNP
cord-310847-63gh2tg4	774	22	)	)	-RRB-
cord-310847-63gh2tg4	774	23	,	,	,
cord-310847-63gh2tg4	774	24	3	3	CD
cord-310847-63gh2tg4	774	25	%	%	NN
cord-310847-63gh2tg4	774	26	are	be	VBP
cord-310847-63gh2tg4	774	27	found	find	VBN
cord-310847-63gh2tg4	774	28	in	in	IN
cord-310847-63gh2tg4	774	29	cone	cone	NN
cord-310847-63gh2tg4	774	30	,	,	,
cord-310847-63gh2tg4	774	31	cone	cone	NN
cord-310847-63gh2tg4	774	32	-	-	HYPH
cord-310847-63gh2tg4	774	33	rod	rod	NN
cord-310847-63gh2tg4	774	34	dystrophy	dystrophy	NN
cord-310847-63gh2tg4	774	35	or	or	CC
cord-310847-63gh2tg4	774	36	atrophic	atrophic	JJ
cord-310847-63gh2tg4	774	37	macular	macular	JJ
cord-310847-63gh2tg4	774	38	atrophy	atrophy	NN
cord-310847-63gh2tg4	774	39	,	,	,
cord-310847-63gh2tg4	774	40	and	and	CC
cord-310847-63gh2tg4	774	41	2	2	CD
cord-310847-63gh2tg4	774	42	%	%	NN
cord-310847-63gh2tg4	774	43	are	be	VBP
cord-310847-63gh2tg4	774	44	related	relate	VBN
cord-310847-63gh2tg4	774	45	to	to	IN
cord-310847-63gh2tg4	774	46	syndromal	syndromal	JJ
cord-310847-63gh2tg4	774	47	retinal	retinal	JJ
cord-310847-63gh2tg4	774	48	dystrophies	dystrophy	NNS
cord-310847-63gh2tg4	774	49	with	with	IN
cord-310847-63gh2tg4	774	50	ciliary	ciliary	JJ
cord-310847-63gh2tg4	774	51	dyskinesia	dyskinesia	NN
cord-310847-63gh2tg4	774	52	and	and	CC
cord-310847-63gh2tg4	774	53	hearing	hearing	NN
cord-310847-63gh2tg4	774	54	loss	loss	NN
cord-310847-63gh2tg4	774	55	.	.	.
cord-310847-63gh2tg4	775	1	245	245	CD
cord-310847-63gh2tg4	776	1	Importantly	importantly	RB
cord-310847-63gh2tg4	776	2	,	,	,
cord-310847-63gh2tg4	776	3	all	all	DT
cord-310847-63gh2tg4	776	4	disease	disease	NN
cord-310847-63gh2tg4	776	5	-	-	HYPH
cord-310847-63gh2tg4	776	6	causing	cause	VBG
cord-310847-63gh2tg4	776	7	mutations	mutation	NNS
cord-310847-63gh2tg4	776	8	occur	occur	VBP
cord-310847-63gh2tg4	776	9	in	in	IN
cord-310847-63gh2tg4	776	10	one	one	CD
cord-310847-63gh2tg4	776	11	or	or	CC
cord-310847-63gh2tg4	776	12	more	more	JJR
cord-310847-63gh2tg4	776	13	RPGR	RPGR	NNP
cord-310847-63gh2tg4	776	14	isoforms	isoform	NNS
cord-310847-63gh2tg4	776	15	containing	contain	VBG
cord-310847-63gh2tg4	776	16	the	the	DT
cord-310847-63gh2tg4	776	17	C	C	NNP
cord-310847-63gh2tg4	776	18	-	-	HYPH
cord-310847-63gh2tg4	776	19	terminal	terminal	NN
cord-310847-63gh2tg4	776	20	exon	exon	NN
cord-310847-63gh2tg4	776	21	open	open	JJ
cord-310847-63gh2tg4	776	22	reading	reading	NN
cord-310847-63gh2tg4	776	23	frame	frame	NN
cord-310847-63gh2tg4	776	24	15	15	CD
cord-310847-63gh2tg4	776	25	(	(	-LRB-
cord-310847-63gh2tg4	776	26	ORF15	ORF15	NNP
cord-310847-63gh2tg4	776	27	)	)	-RRB-
cord-310847-63gh2tg4	776	28	,	,	,
cord-310847-63gh2tg4	776	29	and	and	CC
cord-310847-63gh2tg4	776	30	55	55	CD
cord-310847-63gh2tg4	776	31	%	%	NN
cord-310847-63gh2tg4	776	32	occur	occur	VBP
cord-310847-63gh2tg4	776	33	in	in	IN
cord-310847-63gh2tg4	776	34	a	a	DT
cord-310847-63gh2tg4	776	35	Glu	Glu	NNP
cord-310847-63gh2tg4	776	36	-	-	HYPH
cord-310847-63gh2tg4	776	37	rich	rich	JJ
cord-310847-63gh2tg4	776	38	domain	domain	NN
cord-310847-63gh2tg4	776	39	within	within	IN
cord-310847-63gh2tg4	776	40	exon	exon	NN
cord-310847-63gh2tg4	776	41	ORF15	ORF15	NNP
cord-310847-63gh2tg4	776	42	,	,	,
cord-310847-63gh2tg4	776	43	which	which	WDT
cord-310847-63gh2tg4	776	44	accounts	account	VBZ
cord-310847-63gh2tg4	776	45	for	for	IN
cord-310847-63gh2tg4	776	46	only	only	RB
cord-310847-63gh2tg4	776	47	31	31	CD
cord-310847-63gh2tg4	776	48	%	%	NN
cord-310847-63gh2tg4	776	49	of	of	IN
cord-310847-63gh2tg4	776	50	the	the	DT
cord-310847-63gh2tg4	776	51	protein	protein	NN
cord-310847-63gh2tg4	776	52	.	.	.
cord-310847-63gh2tg4	777	1	245	245	CD
cord-310847-63gh2tg4	777	2	RPGR	RPGR	NNP
cord-310847-63gh2tg4	777	3	(	(	-LRB-
cord-310847-63gh2tg4	777	4	1,020	1,020	CD
cord-310847-63gh2tg4	777	5	residues	residue	NNS
cord-310847-63gh2tg4	777	6	)	)	-RRB-
cord-310847-63gh2tg4	777	7	contains	contain	VBZ
cord-310847-63gh2tg4	777	8	123	123	CD
cord-310847-63gh2tg4	777	9	glutamic	glutamic	NN
cord-310847-63gh2tg4	777	10	acids	acid	NNS
cord-310847-63gh2tg4	777	11	,	,	,
cord-310847-63gh2tg4	777	12	more	more	JJR
cord-310847-63gh2tg4	777	13	than	than	IN
cord-310847-63gh2tg4	777	14	half	half	NN
cord-310847-63gh2tg4	777	15	of	of	IN
cord-310847-63gh2tg4	777	16	which	which	WDT
cord-310847-63gh2tg4	777	17	(	(	-LRB-
cord-310847-63gh2tg4	777	18	70	70	CD
cord-310847-63gh2tg4	777	19	)	)	-RRB-
cord-310847-63gh2tg4	777	20	are	be	VBP
cord-310847-63gh2tg4	777	21	located	locate	VBN
cord-310847-63gh2tg4	777	22	within	within	IN
cord-310847-63gh2tg4	777	23	the	the	DT
cord-310847-63gh2tg4	777	24	C	C	NNP
cord-310847-63gh2tg4	777	25	-	-	HYPH
cord-310847-63gh2tg4	777	26	terminal	terminal	NN
cord-310847-63gh2tg4	777	27	Glu	Glu	NNP
cord-310847-63gh2tg4	777	28	-	-	HYPH
cord-310847-63gh2tg4	777	29	rich	rich	JJ
cord-310847-63gh2tg4	777	30	domain	domain	NN
cord-310847-63gh2tg4	777	31	(	(	-LRB-
cord-310847-63gh2tg4	777	32	residues	residue	NNS
cord-310847-63gh2tg4	777	33	530	530	CD
cord-310847-63gh2tg4	777	34	-	-	HYPH
cord-310847-63gh2tg4	777	35	903	903	CD
cord-310847-63gh2tg4	777	36	)	)	-RRB-
cord-310847-63gh2tg4	777	37	.	.	.
cord-310847-63gh2tg4	778	1	Pyoderma	Pyoderma	NNP
cord-310847-63gh2tg4	778	2	gangrenosum	gangrenosum	NN
cord-310847-63gh2tg4	778	3	and	and	CC
cord-310847-63gh2tg4	778	4	Glu250Gln	Glu250Gln	NFP
cord-310847-63gh2tg4	778	5	mutation	mutation	NN
cord-310847-63gh2tg4	778	6	in	in	IN
cord-310847-63gh2tg4	778	7	PSTPIP1	pstpip1	NN
cord-310847-63gh2tg4	778	8	.	.	.
cord-310847-63gh2tg4	779	1	Pyoderma	Pyoderma	NNP
cord-310847-63gh2tg4	779	2	gangrenosum	gangrenosum	NNP
cord-310847-63gh2tg4	779	3	is	be	VBZ
cord-310847-63gh2tg4	779	4	a	a	DT
cord-310847-63gh2tg4	779	5	condition	condition	NN
cord-310847-63gh2tg4	779	6	that	that	WDT
cord-310847-63gh2tg4	779	7	causes	cause	VBZ
cord-310847-63gh2tg4	779	8	tissue	tissue	NN
cord-310847-63gh2tg4	779	9	to	to	TO
cord-310847-63gh2tg4	779	10	become	become	VB
cord-310847-63gh2tg4	779	11	necrotic	necrotic	JJ
cord-310847-63gh2tg4	779	12	,	,	,
cord-310847-63gh2tg4	779	13	causing	cause	VBG
cord-310847-63gh2tg4	779	14	deep	deep	JJ
cord-310847-63gh2tg4	779	15	ulcers	ulcer	NNS
cord-310847-63gh2tg4	779	16	that	that	WDT
cord-310847-63gh2tg4	779	17	usually	usually	RB
cord-310847-63gh2tg4	779	18	occur	occur	VBP
cord-310847-63gh2tg4	779	19	on	on	IN
cord-310847-63gh2tg4	779	20	legs	leg	NNS
cord-310847-63gh2tg4	779	21	.	.	.
cord-310847-63gh2tg4	780	1	Pyoderma	Pyoderma	NNP
cord-310847-63gh2tg4	780	2	gangrenosum	gangrenosum	NNP
cord-310847-63gh2tg4	780	3	is	be	VBZ
cord-310847-63gh2tg4	780	4	one	one	CD
cord-310847-63gh2tg4	780	5	of	of	IN
cord-310847-63gh2tg4	780	6	the	the	DT
cord-310847-63gh2tg4	780	7	most	most	RBS
cord-310847-63gh2tg4	780	8	common	common	JJ
cord-310847-63gh2tg4	780	9	extra	extra	JJ
cord-310847-63gh2tg4	780	10	-	-	JJ
cord-310847-63gh2tg4	780	11	intestinal	intestinal	JJ
cord-310847-63gh2tg4	780	12	manifestations	manifestation	NNS
cord-310847-63gh2tg4	780	13	of	of	IN
cord-310847-63gh2tg4	780	14	chronic	chronic	JJ
cord-310847-63gh2tg4	780	15	inflammatory	inflammatory	JJ
cord-310847-63gh2tg4	780	16	bowel	bowel	NN
cord-310847-63gh2tg4	780	17	disease	disease	NN
cord-310847-63gh2tg4	780	18	.	.	.
cord-310847-63gh2tg4	781	1	246	246	CD
cord-310847-63gh2tg4	782	1	The	the	DT
cord-310847-63gh2tg4	782	2	disease	disease	NN
cord-310847-63gh2tg4	782	3	is	be	VBZ
cord-310847-63gh2tg4	782	4	caused	cause	VBN
cord-310847-63gh2tg4	782	5	by	by	IN
cord-310847-63gh2tg4	782	6	the	the	DT
cord-310847-63gh2tg4	782	7	alterations	alteration	NNS
cord-310847-63gh2tg4	782	8	in	in	IN
cord-310847-63gh2tg4	782	9	the	the	DT
cord-310847-63gh2tg4	782	10	pathway	pathway	NN
cord-310847-63gh2tg4	782	11	that	that	WDT
cord-310847-63gh2tg4	782	12	links	link	VBZ
cord-310847-63gh2tg4	782	13	the	the	DT
cord-310847-63gh2tg4	782	14	members	member	NNS
cord-310847-63gh2tg4	782	15	of	of	IN
cord-310847-63gh2tg4	782	16	the	the	DT
cord-310847-63gh2tg4	782	17	proline	proline	NN
cord-310847-63gh2tg4	782	18	-	-	HYPH
cord-310847-63gh2tg4	782	19	rich	rich	JJ
cord-310847-63gh2tg4	782	20	,	,	,
cord-310847-63gh2tg4	782	21	glutamic	glutamic	NN
cord-310847-63gh2tg4	782	22	acid	acid	NN
cord-310847-63gh2tg4	782	23	-	-	HYPH
cord-310847-63gh2tg4	782	24	rich	rich	JJ
cord-310847-63gh2tg4	782	25	,	,	,
cord-310847-63gh2tg4	782	26	serine	serine	NN
cord-310847-63gh2tg4	782	27	-	-	HYPH
cord-310847-63gh2tg4	782	28	rich	rich	JJ
cord-310847-63gh2tg4	782	29	and	and	CC
cord-310847-63gh2tg4	782	30	threonine	threonine	JJ
cord-310847-63gh2tg4	782	31	-	-	HYPH
cord-310847-63gh2tg4	782	32	rich	rich	JJ
cord-310847-63gh2tg4	782	33	(	(	-LRB-
cord-310847-63gh2tg4	782	34	PEST	PEST	NNP
cord-310847-63gh2tg4	782	35	)	)	-RRB-
cord-310847-63gh2tg4	782	36	family	family	NN
cord-310847-63gh2tg4	782	37	of	of	IN
cord-310847-63gh2tg4	782	38	protein	protein	NN
cord-310847-63gh2tg4	782	39	tyrosine	tyrosine	NN
cord-310847-63gh2tg4	782	40	phosphatases	phosphatase	NNS
cord-310847-63gh2tg4	782	41	(	(	-LRB-
cord-310847-63gh2tg4	782	42	which	which	WDT
cord-310847-63gh2tg4	782	43	are	be	VBP
cord-310847-63gh2tg4	782	44	critical	critical	JJ
cord-310847-63gh2tg4	782	45	regulators	regulator	NNS
cord-310847-63gh2tg4	782	46	of	of	IN
cord-310847-63gh2tg4	782	47	adhesion	adhesion	NN
cord-310847-63gh2tg4	782	48	and	and	CC
cord-310847-63gh2tg4	782	49	migration	migration	NN
cord-310847-63gh2tg4	782	50	)	)	-RRB-
cord-310847-63gh2tg4	782	51	to	to	IN
cord-310847-63gh2tg4	782	52	their	-PRON-	PRP$
cord-310847-63gh2tg4	782	53	substrates	substrate	NNS
cord-310847-63gh2tg4	782	54	.	.	.
cord-310847-63gh2tg4	783	1	A	a	DT
cord-310847-63gh2tg4	783	2	major	major	JJ
cord-310847-63gh2tg4	783	3	player	player	NN
cord-310847-63gh2tg4	783	4	in	in	IN
cord-310847-63gh2tg4	783	5	this	this	DT
cord-310847-63gh2tg4	783	6	pathway	pathway	NN
cord-310847-63gh2tg4	783	7	is	be	VBZ
cord-310847-63gh2tg4	783	8	a	a	DT
cord-310847-63gh2tg4	783	9	cytoskeleton	cytoskeleton	NN
cord-310847-63gh2tg4	783	10	-	-	HYPH
cord-310847-63gh2tg4	783	11	associated	associate	VBN
cord-310847-63gh2tg4	783	12	adaptor	adaptor	NN
cord-310847-63gh2tg4	783	13	protein	protein	NN
cord-310847-63gh2tg4	783	14	,	,	,
cord-310847-63gh2tg4	783	15	namely	namely	RB
cord-310847-63gh2tg4	783	16	proline	proline	JJ
cord-310847-63gh2tg4	783	17	-	-	HYPH
cord-310847-63gh2tg4	783	18	serine	serine	JJ
cord-310847-63gh2tg4	783	19	-	-	HYPH
cord-310847-63gh2tg4	783	20	threonine	threonine	NN
cord-310847-63gh2tg4	783	21	phosphatase	phosphatase	NN
cord-310847-63gh2tg4	783	22	-	-	HYPH
cord-310847-63gh2tg4	783	23	interacting	interact	VBG
cord-310847-63gh2tg4	783	24	protein	protein	NN
cord-310847-63gh2tg4	783	25	1	1	CD
cord-310847-63gh2tg4	783	26	(	(	-LRB-
cord-310847-63gh2tg4	783	27	PSTPIP1	pstpip1	XX
cord-310847-63gh2tg4	783	28	,	,	,
cord-310847-63gh2tg4	783	29	also	also	RB
cord-310847-63gh2tg4	783	30	known	know	VBN
cord-310847-63gh2tg4	783	31	as	as	IN
cord-310847-63gh2tg4	783	32	CD2-binding	cd2-binde	VBG
cord-310847-63gh2tg4	783	33	protein	protein	NN
cord-310847-63gh2tg4	783	34	1	1	CD
cord-310847-63gh2tg4	783	35	,	,	,
cord-310847-63gh2tg4	783	36	CD2BP1	CD2BP1	NNP
cord-310847-63gh2tg4	783	37	)	)	-RRB-
cord-310847-63gh2tg4	783	38	.	.	.
cord-310847-63gh2tg4	784	1	246	246	CD
cord-310847-63gh2tg4	784	2	Defects	defect	NNS
cord-310847-63gh2tg4	784	3	in	in	IN
cord-310847-63gh2tg4	784	4	PSTPIP1	PSTPIP1	NNS
cord-310847-63gh2tg4	784	5	are	be	VBP
cord-310847-63gh2tg4	784	6	the	the	DT
cord-310847-63gh2tg4	784	7	cause	cause	NN
cord-310847-63gh2tg4	784	8	of	of	IN
cord-310847-63gh2tg4	784	9	PAPA	PAPA	NNP
cord-310847-63gh2tg4	784	10	syndrome	syndrome	NN
cord-310847-63gh2tg4	784	11	(	(	-LRB-
cord-310847-63gh2tg4	784	12	PAPAS	PAPAS	NNP
cord-310847-63gh2tg4	784	13	)	)	-RRB-
cord-310847-63gh2tg4	784	14	,	,	,
cord-310847-63gh2tg4	784	15	also	also	RB
cord-310847-63gh2tg4	784	16	known	know	VBN
cord-310847-63gh2tg4	784	17	as	as	IN
cord-310847-63gh2tg4	784	18	pyogenic	pyogenic	JJ
cord-310847-63gh2tg4	784	19	sterile	sterile	JJ
cord-310847-63gh2tg4	784	20	arthritis	arthritis	NN
cord-310847-63gh2tg4	784	21	,	,	,
cord-310847-63gh2tg4	784	22	pyoderma	pyoderma	NNS
cord-310847-63gh2tg4	784	23	gangrenosum	gangrenosum	NN
cord-310847-63gh2tg4	784	24	and	and	CC
cord-310847-63gh2tg4	784	25	acne	acne	NN
cord-310847-63gh2tg4	784	26	or	or	CC
cord-310847-63gh2tg4	784	27	familial	familial	JJ
cord-310847-63gh2tg4	784	28	recurrent	recurrent	JJ
cord-310847-63gh2tg4	784	29	arthritis	arthritis	NN
cord-310847-63gh2tg4	784	30	(	(	-LRB-
cord-310847-63gh2tg4	784	31	FRA	FRA	NNP
cord-310847-63gh2tg4	784	32	)	)	-RRB-
cord-310847-63gh2tg4	784	33	.	.	.
cord-310847-63gh2tg4	785	1	247	247	CD
cord-310847-63gh2tg4	785	2	PAPAS	PAPAS	NNP
cord-310847-63gh2tg4	785	3	is	be	VBZ
cord-310847-63gh2tg4	785	4	characterized	characterize	VBN
cord-310847-63gh2tg4	785	5	by	by	IN
cord-310847-63gh2tg4	785	6	an	an	DT
cord-310847-63gh2tg4	785	7	autosomal	autosomal	JJ
cord-310847-63gh2tg4	785	8	dominant	dominant	JJ
cord-310847-63gh2tg4	785	9	inheritance	inheritance	NN
cord-310847-63gh2tg4	785	10	of	of	IN
cord-310847-63gh2tg4	785	11	early	early	JJ
cord-310847-63gh2tg4	785	12	onset	onset	NN
cord-310847-63gh2tg4	785	13	,	,	,
cord-310847-63gh2tg4	785	14	primarily	primarily	RB
cord-310847-63gh2tg4	785	15	affecting	affect	VBG
cord-310847-63gh2tg4	785	16	skin	skin	NN
cord-310847-63gh2tg4	785	17	and	and	CC
cord-310847-63gh2tg4	785	18	joint	joint	JJ
cord-310847-63gh2tg4	785	19	tissues	tissue	NNS
cord-310847-63gh2tg4	785	20	.	.	.
cord-310847-63gh2tg4	786	1	Missense	missense	NN
cord-310847-63gh2tg4	786	2	mutations	mutation	NNS
cord-310847-63gh2tg4	786	3	Glu250-Gln	Glu250-Gln	NNP
cord-310847-63gh2tg4	786	4	and	and	CC
cord-310847-63gh2tg4	786	5	Ala230-Thr	Ala230-Thr	NNP
cord-310847-63gh2tg4	786	6	in	in	IN
cord-310847-63gh2tg4	786	7	PSTPIP1	pstpip1	XX
cord-310847-63gh2tg4	786	8	/	/	SYM
cord-310847-63gh2tg4	786	9	CD2BP1	CD2BP1	NNS
cord-310847-63gh2tg4	786	10	were	be	VBD
cord-310847-63gh2tg4	786	11	identified	identify	VBN
cord-310847-63gh2tg4	786	12	in	in	IN
cord-310847-63gh2tg4	786	13	two	two	CD
cord-310847-63gh2tg4	786	14	families	family	NNS
cord-310847-63gh2tg4	786	15	.	.	.
cord-310847-63gh2tg4	787	1	247	247	CD
cord-310847-63gh2tg4	788	1	These	these	DT
cord-310847-63gh2tg4	788	2	mutations	mutation	NNS
cord-310847-63gh2tg4	788	3	were	be	VBD
cord-310847-63gh2tg4	788	4	shown	show	VBN
cord-310847-63gh2tg4	788	5	to	to	TO
cord-310847-63gh2tg4	788	6	affect	affect	VB
cord-310847-63gh2tg4	788	7	the	the	DT
cord-310847-63gh2tg4	788	8	ability	ability	NN
cord-310847-63gh2tg4	788	9	of	of	IN
cord-310847-63gh2tg4	788	10	PSTPIP1to	PSTPIP1to	NNPS
cord-310847-63gh2tg4	788	11	interact	interact	VB
cord-310847-63gh2tg4	788	12	with	with	IN
cord-310847-63gh2tg4	788	13	its	-PRON-	PRP$
cord-310847-63gh2tg4	788	14	natural	natural	JJ
cord-310847-63gh2tg4	788	15	partners	partner	NNS
cord-310847-63gh2tg4	788	16	.	.	.
cord-310847-63gh2tg4	789	1	247	247	CD
cord-310847-63gh2tg4	789	2	,	,	,
cord-310847-63gh2tg4	789	3	248	248	CD
cord-310847-63gh2tg4	790	1	and	and	CC
cord-310847-63gh2tg4	790	2	BEAF32	BEAF32	NNP
cord-310847-63gh2tg4	790	3	.	.	.
cord-310847-63gh2tg4	790	4	240	240	CD
cord-310847-63gh2tg4	791	1	Although	although	IN
cord-310847-63gh2tg4	791	2	Cp190	Cp190	NNP
cord-310847-63gh2tg4	791	3	is	be	VBZ
cord-310847-63gh2tg4	791	4	a	a	DT
cord-310847-63gh2tg4	791	5	large	large	JJ
cord-310847-63gh2tg4	791	6	protein	protein	NN
cord-310847-63gh2tg4	791	7	(	(	-LRB-
cord-310847-63gh2tg4	791	8	1,096	1,096	CD
cord-310847-63gh2tg4	791	9	residues	residue	NNS
cord-310847-63gh2tg4	791	10	)	)	-RRB-
cord-310847-63gh2tg4	791	11	that	that	WDT
cord-310847-63gh2tg4	791	12	possesses	possess	VBZ
cord-310847-63gh2tg4	791	13	a	a	DT
cord-310847-63gh2tg4	791	14	complex	complex	JJ
cord-310847-63gh2tg4	791	15	multidomain	multidomain	NN
cord-310847-63gh2tg4	791	16	structure	structure	NN
cord-310847-63gh2tg4	791	17	,	,	,
cord-310847-63gh2tg4	791	18	only	only	RB
cord-310847-63gh2tg4	791	19	three	three	CD
cord-310847-63gh2tg4	791	20	domains	domain	NNS
cord-310847-63gh2tg4	791	21	were	be	VBD
cord-310847-63gh2tg4	791	22	shown	show	VBN
cord-310847-63gh2tg4	791	23	to	to	TO
cord-310847-63gh2tg4	791	24	be	be	VB
cord-310847-63gh2tg4	791	25	essential	essential	JJ
cord-310847-63gh2tg4	791	26	for	for	IN
cord-310847-63gh2tg4	791	27	the	the	DT
cord-310847-63gh2tg4	791	28	insulator	insulator	NN
cord-310847-63gh2tg4	791	29	function	function	NN
cord-310847-63gh2tg4	791	30	and	and	CC
cord-310847-63gh2tg4	791	31	for	for	IN
cord-310847-63gh2tg4	791	32	the	the	DT
cord-310847-63gh2tg4	791	33	viability	viability	NN
cord-310847-63gh2tg4	791	34	of	of	IN
cord-310847-63gh2tg4	791	35	flies	fly	NNS
cord-310847-63gh2tg4	791	36	:	:	:
cord-310847-63gh2tg4	791	37	the	the	DT
cord-310847-63gh2tg4	791	38	BTB	BTB	NNP
cord-310847-63gh2tg4	791	39	/	/	SYM
cord-310847-63gh2tg4	791	40	POZ	POZ	NNP
cord-310847-63gh2tg4	791	41	domain	domain	NN
cord-310847-63gh2tg4	791	42	,	,	,
cord-310847-63gh2tg4	791	43	an	an	DT
cord-310847-63gh2tg4	791	44	aspartic	aspartic	JJ
cord-310847-63gh2tg4	791	45	acid	acid	NN
cord-310847-63gh2tg4	791	46	-	-	HYPH
cord-310847-63gh2tg4	791	47	rich	rich	JJ
cord-310847-63gh2tg4	791	48	(	(	-LRB-
cord-310847-63gh2tg4	791	49	D	d	JJ
cord-310847-63gh2tg4	791	50	-	-	HYPH
cord-310847-63gh2tg4	791	51	rich	rich	JJ
cord-310847-63gh2tg4	791	52	)	)	-RRB-
cord-310847-63gh2tg4	791	53	region	region	NN
cord-310847-63gh2tg4	791	54	and	and	CC
cord-310847-63gh2tg4	791	55	a	a	DT
cord-310847-63gh2tg4	791	56	C	c	NN
cord-310847-63gh2tg4	791	57	-	-	HYPH
cord-310847-63gh2tg4	791	58	terminal	terminal	NN
cord-310847-63gh2tg4	791	59	glutamic	glutamic	NN
cord-310847-63gh2tg4	791	60	acid	acid	NN
cord-310847-63gh2tg4	791	61	-	-	HYPH
cord-310847-63gh2tg4	791	62	rich	rich	JJ
cord-310847-63gh2tg4	791	63	(	(	-LRB-
cord-310847-63gh2tg4	791	64	E	e	NN
cord-310847-63gh2tg4	791	65	-	-	JJ
cord-310847-63gh2tg4	791	66	rich	rich	JJ
cord-310847-63gh2tg4	791	67	)	)	-RRB-
cord-310847-63gh2tg4	791	68	region	region	NN
cord-310847-63gh2tg4	791	69	.	.	.
cord-310847-63gh2tg4	792	1	240	240	CD
cord-310847-63gh2tg4	793	1	Here	here	RB
cord-310847-63gh2tg4	793	2	,	,	,
cord-310847-63gh2tg4	793	3	the	the	DT
cord-310847-63gh2tg4	793	4	N	n	CD
cord-310847-63gh2tg4	793	5	-	-	HYPH
cord-310847-63gh2tg4	793	6	terminal	terminal	NN
cord-310847-63gh2tg4	793	7	Cp190	Cp190	NNP
cord-310847-63gh2tg4	793	8	fragment	fragment	NN
cord-310847-63gh2tg4	793	9	containing	contain	VBG
cord-310847-63gh2tg4	793	10	the	the	DT
cord-310847-63gh2tg4	793	11	BTB	BTB	NNP
cord-310847-63gh2tg4	793	12	/	/	SYM
cord-310847-63gh2tg4	793	13	POZ	POZ	NNP
cord-310847-63gh2tg4	793	14	domain	domain	NN
cord-310847-63gh2tg4	793	15	and	and	CC
cord-310847-63gh2tg4	793	16	the	the	DT
cord-310847-63gh2tg4	793	17	D	d	NN
cord-310847-63gh2tg4	793	18	-	-	HYPH
cord-310847-63gh2tg4	793	19	rich	rich	JJ
cord-310847-63gh2tg4	793	20	region	region	NN
cord-310847-63gh2tg4	793	21	was	be	VBD
cord-310847-63gh2tg4	793	22	shown	show	VBN
cord-310847-63gh2tg4	793	23	to	to	TO
cord-310847-63gh2tg4	793	24	be	be	VB
cord-310847-63gh2tg4	793	25	involved	involve	VBN
cord-310847-63gh2tg4	793	26	in	in	IN
cord-310847-63gh2tg4	793	27	regulation	regulation	NN
cord-310847-63gh2tg4	793	28	of	of	IN
cord-310847-63gh2tg4	793	29	the	the	DT
cord-310847-63gh2tg4	793	30	Cp190	Cp190	NNP
cord-310847-63gh2tg4	793	31	interaction	interaction	NN
cord-310847-63gh2tg4	793	32	with	with	IN
cord-310847-63gh2tg4	793	33	insulator	insulator	NN
cord-310847-63gh2tg4	793	34	complexes	complex	NNS
cord-310847-63gh2tg4	793	35	,	,	,
cord-310847-63gh2tg4	793	36	whereas	whereas	IN
cord-310847-63gh2tg4	793	37	the	the	DT
cord-310847-63gh2tg4	793	38	C	C	NNP
cord-310847-63gh2tg4	793	39	-	-	HYPH
cord-310847-63gh2tg4	793	40	terminally	terminally	RB
cord-310847-63gh2tg4	793	41	located	locate	VBN
cord-310847-63gh2tg4	793	42	E	e	NN
cord-310847-63gh2tg4	793	43	-	-	JJ
cord-310847-63gh2tg4	793	44	rich	rich	JJ
cord-310847-63gh2tg4	793	45	region	region	NN
cord-310847-63gh2tg4	793	46	was	be	VBD
cord-310847-63gh2tg4	793	47	necessary	necessary	JJ
cord-310847-63gh2tg4	793	48	for	for	IN
cord-310847-63gh2tg4	793	49	the	the	DT
cord-310847-63gh2tg4	793	50	Cp190	Cp190	NNP
cord-310847-63gh2tg4	793	51	dissociation	dissociation	NN
cord-310847-63gh2tg4	793	52	from	from	IN
cord-310847-63gh2tg4	793	53	chromosomes	chromosome	NNS
cord-310847-63gh2tg4	793	54	during	during	IN
cord-310847-63gh2tg4	793	55	heat	heat	NN
cord-310847-63gh2tg4	793	56	-	-	HYPH
cord-310847-63gh2tg4	793	57	shock	shock	NN
cord-310847-63gh2tg4	793	58	.	.	.
cord-310847-63gh2tg4	794	1	240	240	CD
cord-310847-63gh2tg4	795	1	Importantly	importantly	RB
cord-310847-63gh2tg4	795	2	,	,	,
cord-310847-63gh2tg4	795	3	the	the	DT
cord-310847-63gh2tg4	795	4	131	131	CD
cord-310847-63gh2tg4	795	5	glutamic	glutamic	JJ
cord-310847-63gh2tg4	795	6	acids	acid	NNS
cord-310847-63gh2tg4	795	7	are	be	VBP
cord-310847-63gh2tg4	795	8	not	not	RB
cord-310847-63gh2tg4	795	9	equally	equally	RB
cord-310847-63gh2tg4	795	10	distributed	distribute	VBN
cord-310847-63gh2tg4	795	11	within	within	IN
cord-310847-63gh2tg4	795	12	the	the	DT
cord-310847-63gh2tg4	795	13	protein	protein	NN
cord-310847-63gh2tg4	795	14	,	,	,
cord-310847-63gh2tg4	795	15	with	with	IN
cord-310847-63gh2tg4	795	16	the	the	DT
cord-310847-63gh2tg4	795	17	N	n	CD
cord-310847-63gh2tg4	795	18	-	-	HYPH
cord-310847-63gh2tg4	795	19	terminal	terminal	NN
cord-310847-63gh2tg4	795	20	half	half	NN
cord-310847-63gh2tg4	795	21	containing	contain	VBG
cord-310847-63gh2tg4	795	22	just	just	RB
cord-310847-63gh2tg4	795	23	26	26	CD
cord-310847-63gh2tg4	795	24	glutamic	glutamic	NN
cord-310847-63gh2tg4	795	25	acids	acid	NNS
cord-310847-63gh2tg4	795	26	and	and	CC
cord-310847-63gh2tg4	795	27	with	with	IN
cord-310847-63gh2tg4	795	28	the	the	DT
cord-310847-63gh2tg4	795	29	remaining	remain	VBG
cord-310847-63gh2tg4	795	30	105	105	CD
cord-310847-63gh2tg4	795	31	glutamates	glutamate	NNS
cord-310847-63gh2tg4	795	32	being	be	VBG
cord-310847-63gh2tg4	795	33	concentrated	concentrate	VBN
cord-310847-63gh2tg4	795	34	within	within	IN
cord-310847-63gh2tg4	795	35	the	the	DT
cord-310847-63gh2tg4	795	36	C	C	NNP
cord-310847-63gh2tg4	795	37	-	-	HYPH
cord-310847-63gh2tg4	795	38	terminal	terminal	NN
cord-310847-63gh2tg4	795	39	half	half	NN
cord-310847-63gh2tg4	795	40	of	of	IN
cord-310847-63gh2tg4	795	41	Cp190	Cp190	NNP
cord-310847-63gh2tg4	795	42	.	.	.
cord-310847-63gh2tg4	796	1	Therefore	therefore	RB
cord-310847-63gh2tg4	796	2	,	,	,
cord-310847-63gh2tg4	796	3	although	although	IN
cord-310847-63gh2tg4	796	4	the	the	DT
cord-310847-63gh2tg4	796	5	overall	overall	JJ
cord-310847-63gh2tg4	796	6	glutamic	glutamic	NN
cord-310847-63gh2tg4	796	7	acid	acid	NN
cord-310847-63gh2tg4	796	8	content	content	NN
cord-310847-63gh2tg4	796	9	of	of	IN
cord-310847-63gh2tg4	796	10	this	this	DT
cord-310847-63gh2tg4	796	11	protein	protein	NN
cord-310847-63gh2tg4	796	12	is	be	VBZ
cord-310847-63gh2tg4	796	13	12	12	CD
cord-310847-63gh2tg4	796	14	%	%	NN
cord-310847-63gh2tg4	796	15	,	,	,
cord-310847-63gh2tg4	796	16	its	-PRON-	PRP$
cord-310847-63gh2tg4	796	17	C	c	NN
cord-310847-63gh2tg4	796	18	-	-	HYPH
cord-310847-63gh2tg4	796	19	terminal	terminal	NN
cord-310847-63gh2tg4	796	20	half	half	NN
cord-310847-63gh2tg4	796	21	is	be	VBZ
cord-310847-63gh2tg4	796	22	especially	especially	RB
cord-310847-63gh2tg4	796	23	enriched	enrich	VBN
cord-310847-63gh2tg4	796	24	in	in	IN
cord-310847-63gh2tg4	796	25	these	these	DT
cord-310847-63gh2tg4	796	26	residues	residue	NNS
cord-310847-63gh2tg4	796	27	(	(	-LRB-
cord-310847-63gh2tg4	796	28	19.2	19.2	CD
cord-310847-63gh2tg4	796	29	%	%	NN
cord-310847-63gh2tg4	796	30	)	)	-RRB-
cord-310847-63gh2tg4	796	31	.	.	.
cord-310847-63gh2tg4	797	1	Also	also	RB
cord-310847-63gh2tg4	797	2	,	,	,
cord-310847-63gh2tg4	797	3	this	this	DT
cord-310847-63gh2tg4	797	4	uneven	uneven	JJ
cord-310847-63gh2tg4	797	5	distribution	distribution	NN
cord-310847-63gh2tg4	797	6	is	be	VBZ
cord-310847-63gh2tg4	797	7	seen	see	VBN
cord-310847-63gh2tg4	797	8	not	not	RB
cord-310847-63gh2tg4	797	9	only	only	RB
cord-310847-63gh2tg4	797	10	for	for	IN
cord-310847-63gh2tg4	797	11	Glu	Glu	NNP
cord-310847-63gh2tg4	797	12	,	,	,
cord-310847-63gh2tg4	797	13	but	but	CC
cord-310847-63gh2tg4	797	14	for	for	IN
cord-310847-63gh2tg4	797	15	all	all	PDT
cord-310847-63gh2tg4	797	16	the	the	DT
cord-310847-63gh2tg4	797	17	charged	charge	VBN
cord-310847-63gh2tg4	797	18	residues	residue	NNS
cord-310847-63gh2tg4	797	19	.	.	.
cord-310847-63gh2tg4	798	1	In	in	IN
cord-310847-63gh2tg4	798	2	fact	fact	NN
cord-310847-63gh2tg4	798	3	,	,	,
cord-310847-63gh2tg4	798	4	the	the	DT
cord-310847-63gh2tg4	798	5	N	n	CD
cord-310847-63gh2tg4	798	6	-	-	HYPH
cord-310847-63gh2tg4	798	7	terminal	terminal	NN
cord-310847-63gh2tg4	798	8	fragment	fragment	NN
cord-310847-63gh2tg4	798	9	(	(	-LRB-
cord-310847-63gh2tg4	798	10	residues	residue	NNS
cord-310847-63gh2tg4	798	11	1	1	CD
cord-310847-63gh2tg4	798	12	-	-	SYM
cord-310847-63gh2tg4	798	13	548	548	CD
cord-310847-63gh2tg4	798	14	)	)	-RRB-
cord-310847-63gh2tg4	798	15	has	have	VBZ
cord-310847-63gh2tg4	798	16	a	a	DT
cord-310847-63gh2tg4	798	17	net	net	JJ
cord-310847-63gh2tg4	798	18	charge	charge	NN
cord-310847-63gh2tg4	798	19	of	of	IN
cord-310847-63gh2tg4	798	20	+18	+18	CD
cord-310847-63gh2tg4	799	1	(	(	-LRB-
cord-310847-63gh2tg4	799	2	Asp	Asp	NNP
cord-310847-63gh2tg4	799	3	+	+	CC
cord-310847-63gh2tg4	799	4	Glu	glu	NN
cord-310847-63gh2tg4	799	5	=	=	NFP
cord-310847-63gh2tg4	800	1	25	25	CD
cord-310847-63gh2tg4	800	2	+	+	CC
cord-310847-63gh2tg4	801	1	26	26	CD
cord-310847-63gh2tg4	801	2	=	=	SYM
cord-310847-63gh2tg4	801	3	51	51	CD
cord-310847-63gh2tg4	801	4	;	;	:
cord-310847-63gh2tg4	801	5	Arg	Arg	NNP
cord-310847-63gh2tg4	801	6	+	+	CC
cord-310847-63gh2tg4	801	7	Lys	Lys	NNP
cord-310847-63gh2tg4	801	8	=	=	SYM
cord-310847-63gh2tg4	801	9	31	31	CD
cord-310847-63gh2tg4	801	10	+	+	SYM
cord-310847-63gh2tg4	801	11	38	38	CD
cord-310847-63gh2tg4	801	12	=	=	SYM
cord-310847-63gh2tg4	801	13	69	69	CD
cord-310847-63gh2tg4	801	14	)	)	-RRB-
cord-310847-63gh2tg4	801	15	,	,	.
cord-310847-63gh2tg4	802	1	whereas	whereas	IN
cord-310847-63gh2tg4	802	2	the	the	DT
cord-310847-63gh2tg4	802	3	C	C	NNP
cord-310847-63gh2tg4	802	4	-	-	HYPH
cord-310847-63gh2tg4	802	5	terminal	terminal	NN
cord-310847-63gh2tg4	802	6	half	half	NN
cord-310847-63gh2tg4	802	7	of	of	IN
cord-310847-63gh2tg4	802	8	Cp190	Cp190	NNP
cord-310847-63gh2tg4	802	9	(	(	-LRB-
cord-310847-63gh2tg4	802	10	residues	residue	NNS
cord-310847-63gh2tg4	802	11	549	549	CD
cord-310847-63gh2tg4	802	12	-	-	HYPH
cord-310847-63gh2tg4	802	13	1096	1096	CD
cord-310847-63gh2tg4	802	14	)	)	-RRB-
cord-310847-63gh2tg4	802	15	has	have	VBZ
cord-310847-63gh2tg4	802	16	a	a	DT
cord-310847-63gh2tg4	802	17	net	net	JJ
cord-310847-63gh2tg4	802	18	charge	charge	NN
cord-310847-63gh2tg4	802	19	of	of	IN
cord-310847-63gh2tg4	802	20	−120	−120	ADD
cord-310847-63gh2tg4	803	1	(	(	-LRB-
cord-310847-63gh2tg4	803	2	Asp	Asp	NNP
cord-310847-63gh2tg4	803	3	+	+	CC
cord-310847-63gh2tg4	803	4	Glu	glu	NN
cord-310847-63gh2tg4	803	5	=	=	NFP
cord-310847-63gh2tg4	804	1	62	62	CD
cord-310847-63gh2tg4	804	2	+	+	CC
cord-310847-63gh2tg4	805	1	105	105	CD
cord-310847-63gh2tg4	805	2	=	=	SYM
cord-310847-63gh2tg4	805	3	167	167	CD
cord-310847-63gh2tg4	805	4	;	;	:
cord-310847-63gh2tg4	805	5	Arg	Arg	NNP
cord-310847-63gh2tg4	805	6	+	+	CC
cord-310847-63gh2tg4	805	7	Lys	Lys	NNP
cord-310847-63gh2tg4	805	8	=	=	SYM
cord-310847-63gh2tg4	805	9	8	8	CD
cord-310847-63gh2tg4	805	10	+	+	SYM
cord-310847-63gh2tg4	805	11	39	39	CD
cord-310847-63gh2tg4	805	12	=	=	SYM
cord-310847-63gh2tg4	805	13	47	47	CD
cord-310847-63gh2tg4	805	14	)	)	-RRB-
cord-310847-63gh2tg4	805	15	.	.	.
cord-310847-63gh2tg4	806	1	Pcp4l1	pcp4l1	UH
cord-310847-63gh2tg4	806	2	.	.	.
cord-310847-63gh2tg4	807	1	Purkinje	purkinje	JJ
cord-310847-63gh2tg4	807	2	cell	cell	NN
cord-310847-63gh2tg4	807	3	produces	produce	VBZ
cord-310847-63gh2tg4	807	4	two	two	CD
cord-310847-63gh2tg4	807	5	closely	closely	RB
cord-310847-63gh2tg4	807	6	related	related	JJ
cord-310847-63gh2tg4	807	7	proteins	protein	NNS
cord-310847-63gh2tg4	807	8	containing	contain	VBG
cord-310847-63gh2tg4	807	9	IQ	iq	NN
cord-310847-63gh2tg4	807	10	motifs	motif	NNS
cord-310847-63gh2tg4	807	11	,	,	,
cord-310847-63gh2tg4	807	12	Purkinje	Purkinje	NNP
cord-310847-63gh2tg4	807	13	cell	cell	NN
cord-310847-63gh2tg4	807	14	protein	protein	NN
cord-310847-63gh2tg4	807	15	4-like	4-like	CD
cord-310847-63gh2tg4	807	16	1	1	CD
cord-310847-63gh2tg4	807	17	(	(	-LRB-
cord-310847-63gh2tg4	807	18	Pcp4l1	pcp4l1	NN
cord-310847-63gh2tg4	807	19	)	)	-RRB-
cord-310847-63gh2tg4	807	20	and	and	CC
cord-310847-63gh2tg4	807	21	Pcp4	Pcp4	NNP
cord-310847-63gh2tg4	807	22	/	/	SYM
cord-310847-63gh2tg4	807	23	PEP-19	PEP-19	NNP
cord-310847-63gh2tg4	807	24	.	.	.
cord-310847-63gh2tg4	808	1	Although	although	IN
cord-310847-63gh2tg4	808	2	Pcp4	Pcp4	NNP
cord-310847-63gh2tg4	808	3	/	/	SYM
cord-310847-63gh2tg4	808	4	PEP-19	PEP-19	NNP
cord-310847-63gh2tg4	808	5	is	be	VBZ
cord-310847-63gh2tg4	808	6	able	able	JJ
cord-310847-63gh2tg4	808	7	to	to	TO
cord-310847-63gh2tg4	808	8	interact	interact	VB
cord-310847-63gh2tg4	808	9	with	with	IN
cord-310847-63gh2tg4	808	10	calmodulin	calmodulin	NN
cord-310847-63gh2tg4	808	11	and	and	CC
cord-310847-63gh2tg4	808	12	inhibit	inhibit	VB
cord-310847-63gh2tg4	808	13	calmodulin	calmodulin	NN
cord-310847-63gh2tg4	808	14	-	-	HYPH
cord-310847-63gh2tg4	808	15	dependent	dependent	JJ
cord-310847-63gh2tg4	808	16	enzymes	enzyme	NNS
cord-310847-63gh2tg4	808	17	,	,	,
cord-310847-63gh2tg4	808	18	and	and	CC
cord-310847-63gh2tg4	808	19	although	although	IN
cord-310847-63gh2tg4	808	20	the	the	DT
cord-310847-63gh2tg4	808	21	synthetic	synthetic	JJ
cord-310847-63gh2tg4	808	22	peptide	peptide	NN
cord-310847-63gh2tg4	808	23	constituting	constitute	VBG
cord-310847-63gh2tg4	808	24	only	only	RB
cord-310847-63gh2tg4	808	25	the	the	DT
cord-310847-63gh2tg4	808	26	IQ	iq	NN
cord-310847-63gh2tg4	808	27	motif	motif	NN
cord-310847-63gh2tg4	808	28	of	of	IN
cord-310847-63gh2tg4	808	29	Pcp4l1	pcp4l1	NN
cord-310847-63gh2tg4	808	30	binds	bind	VBZ
cord-310847-63gh2tg4	808	31	calmodulin	calmodulin	NN
cord-310847-63gh2tg4	808	32	and	and	CC
cord-310847-63gh2tg4	808	33	inhibits	inhibit	VBZ
cord-310847-63gh2tg4	808	34	calmodulin	calmodulin	NN
cord-310847-63gh2tg4	808	35	-	-	HYPH
cord-310847-63gh2tg4	808	36	dependent	dependent	JJ
cord-310847-63gh2tg4	808	37	kinase	kinase	NN
cord-310847-63gh2tg4	808	38	II	II	NNP
cord-310847-63gh2tg4	808	39	,	,	,
cord-310847-63gh2tg4	808	40	the	the	DT
cord-310847-63gh2tg4	808	41	full	full	JJ
cord-310847-63gh2tg4	808	42	-	-	HYPH
cord-310847-63gh2tg4	808	43	length	length	NN
cord-310847-63gh2tg4	808	44	Pcp4l1	pcp4l1	NN
cord-310847-63gh2tg4	808	45	does	do	VBZ
cord-310847-63gh2tg4	808	46	not	not	RB
cord-310847-63gh2tg4	808	47	interact	interact	VB
cord-310847-63gh2tg4	808	48	with	with	IN
cord-310847-63gh2tg4	808	49	calmodulin	calmodulin	NNP
cord-310847-63gh2tg4	808	50	.	.	.
cord-310847-63gh2tg4	809	1	241	241	CD
cord-310847-63gh2tg4	810	1	The	the	DT
cord-310847-63gh2tg4	810	2	lack	lack	NN
cord-310847-63gh2tg4	810	3	of	of	IN
cord-310847-63gh2tg4	810	4	ability	ability	NN
cord-310847-63gh2tg4	810	5	of	of	IN
cord-310847-63gh2tg4	810	6	the	the	DT
cord-310847-63gh2tg4	810	7	full	full	JJ
cord-310847-63gh2tg4	810	8	length	length	NN
cord-310847-63gh2tg4	810	9	Pcp4l1	pcp4l1	ADD
cord-310847-63gh2tg4	810	10	to	to	TO
cord-310847-63gh2tg4	810	11	interact	interact	VB
cord-310847-63gh2tg4	810	12	with	with	IN
cord-310847-63gh2tg4	810	13	calmodulin	calmodulin	NNP
cord-310847-63gh2tg4	810	14	was	be	VBD
cord-310847-63gh2tg4	810	15	ascribed	ascribe	VBN
cord-310847-63gh2tg4	810	16	to	to	IN
cord-310847-63gh2tg4	810	17	its	-PRON-	PRP$
cord-310847-63gh2tg4	810	18	nine	nine	CD
cord-310847-63gh2tg4	810	19	-	-	HYPH
cord-310847-63gh2tg4	810	20	residue	residue	NN
cord-310847-63gh2tg4	810	21	glutamic	glutamic	NN
cord-310847-63gh2tg4	810	22	acid	acid	NN
cord-310847-63gh2tg4	810	23	-	-	HYPH
cord-310847-63gh2tg4	810	24	rich	rich	JJ
cord-310847-63gh2tg4	810	25	sequence	sequence	NN
cord-310847-63gh2tg4	810	26	that	that	WDT
cord-310847-63gh2tg4	810	27	lies	lie	VBZ
cord-310847-63gh2tg4	810	28	outside	outside	IN
cord-310847-63gh2tg4	810	29	the	the	DT
cord-310847-63gh2tg4	810	30	IQ	IQ	NNP
cord-310847-63gh2tg4	810	31	motif	motif	NN
cord-310847-63gh2tg4	810	32	in	in	IN
cord-310847-63gh2tg4	810	33	Pcp4l1	pcp4l1	ADD
cord-310847-63gh2tg4	810	34	.	.	.
cord-310847-63gh2tg4	811	1	Mutational	mutational	JJ
cord-310847-63gh2tg4	811	2	analysis	analysis	NN
cord-310847-63gh2tg4	811	3	showed	show	VBD
cord-310847-63gh2tg4	811	4	that	that	IN
cord-310847-63gh2tg4	811	5	calmodulin	calmodulin	NN
cord-310847-63gh2tg4	811	6	binding	binding	NN
cord-310847-63gh2tg4	811	7	can	can	MD
cord-310847-63gh2tg4	811	8	be	be	VB
cord-310847-63gh2tg4	811	9	restored	restore	VBN
cord-310847-63gh2tg4	811	10	not	not	RB
cord-310847-63gh2tg4	811	11	only	only	RB
cord-310847-63gh2tg4	811	12	by	by	IN
cord-310847-63gh2tg4	811	13	the	the	DT
cord-310847-63gh2tg4	811	14	deletion	deletion	NN
cord-310847-63gh2tg4	811	15	of	of	IN
cord-310847-63gh2tg4	811	16	this	this	DT
cord-310847-63gh2tg4	811	17	inhibitory	inhibitory	JJ
cord-310847-63gh2tg4	811	18	motif	motif	NN
cord-310847-63gh2tg4	811	19	,	,	,
cord-310847-63gh2tg4	811	20	but	but	CC
cord-310847-63gh2tg4	811	21	also	also	RB
cord-310847-63gh2tg4	811	22	by	by	IN
cord-310847-63gh2tg4	811	23	exchanging	exchange	VBG
cord-310847-63gh2tg4	811	24	it	-PRON-	PRP
cord-310847-63gh2tg4	811	25	with	with	IN
cord-310847-63gh2tg4	811	26	the	the	DT
cord-310847-63gh2tg4	811	27	homologous	homologous	JJ
cord-310847-63gh2tg4	811	28	region	region	NN
cord-310847-63gh2tg4	811	29	of	of	IN
cord-310847-63gh2tg4	811	30	PEP-19	PEP-19	NNP
cord-310847-63gh2tg4	811	31	and	and	CC
cord-310847-63gh2tg4	811	32	by	by	IN
cord-310847-63gh2tg4	811	33	simple	simple	JJ
cord-310847-63gh2tg4	811	34	point	point	NN
cord-310847-63gh2tg4	811	35	mutation	mutation	NN
cord-310847-63gh2tg4	811	36	converting	convert	VBG
cord-310847-63gh2tg4	811	37	a	a	DT
cord-310847-63gh2tg4	811	38	single	single	JJ
cord-310847-63gh2tg4	811	39	isoleucine	isoleucine	NN
cord-310847-63gh2tg4	811	40	(	(	-LRB-
cord-310847-63gh2tg4	811	41	Ile36	Ile36	NNP
cord-310847-63gh2tg4	811	42	)	)	-RRB-
cord-310847-63gh2tg4	811	43	within	within	IN
cord-310847-63gh2tg4	811	44	this	this	DT
cord-310847-63gh2tg4	811	45	motif	motif	NN
cord-310847-63gh2tg4	811	46	to	to	IN
cord-310847-63gh2tg4	811	47	phenylalanine	phenylalanine	NN
cord-310847-63gh2tg4	811	48	or	or	CC
cord-310847-63gh2tg4	811	49	to	to	IN
cord-310847-63gh2tg4	811	50	other	other	JJ
cord-310847-63gh2tg4	811	51	aromatic	aromatic	JJ
cord-310847-63gh2tg4	811	52	residues	residue	NNS
cord-310847-63gh2tg4	811	53	.	.	.
cord-310847-63gh2tg4	812	1	241	241	CD
cord-310847-63gh2tg4	813	1	Therefore	therefore	RB
cord-310847-63gh2tg4	813	2	,	,	,
cord-310847-63gh2tg4	813	3	although	although	IN
cord-310847-63gh2tg4	813	4	PEP-19	PEP-19	NNP
cord-310847-63gh2tg4	813	5	and	and	CC
cord-310847-63gh2tg4	813	6	Pcp4l1	pcp4l1	PRP
cord-310847-63gh2tg4	813	7	possess	possess	VBP
cord-310847-63gh2tg4	813	8	noticeable	noticeable	JJ
cord-310847-63gh2tg4	813	9	sequence	sequence	NN
cord-310847-63gh2tg4	813	10	similarities	similarity	NNS
cord-310847-63gh2tg4	813	11	,	,	,
cord-310847-63gh2tg4	813	12	their	-PRON-	PRP$
cord-310847-63gh2tg4	813	13	functional	functional	JJ
cord-310847-63gh2tg4	813	14	properties	property	NNS
cord-310847-63gh2tg4	813	15	are	be	VBP
cord-310847-63gh2tg4	813	16	very	very	RB
cord-310847-63gh2tg4	813	17	different	different	JJ
cord-310847-63gh2tg4	813	18	due	due	IN
cord-310847-63gh2tg4	813	19	to	to	IN
cord-310847-63gh2tg4	813	20	the	the	DT
cord-310847-63gh2tg4	813	21	presence	presence	NN
cord-310847-63gh2tg4	813	22	of	of	IN
cord-310847-63gh2tg4	813	23	the	the	DT
cord-310847-63gh2tg4	813	24	Glu	Glu	NNP
cord-310847-63gh2tg4	813	25	-	-	HYPH
cord-310847-63gh2tg4	813	26	rich	rich	JJ
cord-310847-63gh2tg4	813	27	element	element	NN
cord-310847-63gh2tg4	813	28	in	in	IN
cord-310847-63gh2tg4	813	29	Pcp4l1	pcp4l1	ADD
cord-310847-63gh2tg4	813	30	that	that	WDT
cord-310847-63gh2tg4	813	31	can	can	MD
cord-310847-63gh2tg4	813	32	functionally	functionally	RB
cord-310847-63gh2tg4	813	33	suppress	suppress	VB
cord-310847-63gh2tg4	813	34	an	an	DT
cord-310847-63gh2tg4	813	35	IQ	iq	NN
cord-310847-63gh2tg4	813	36	motif	motif	NN
cord-310847-63gh2tg4	813	37	.	.	.
cord-310847-63gh2tg4	814	1	241	241	CD
cord-310847-63gh2tg4	814	2	Glutamic	glutamic	NN
cord-310847-63gh2tg4	814	3	acid	acid	NN
cord-310847-63gh2tg4	814	4	mutations	mutation	NNS
cord-310847-63gh2tg4	814	5	and	and	CC
cord-310847-63gh2tg4	814	6	human	human	JJ
cord-310847-63gh2tg4	814	7	diseases	disease	NNS
cord-310847-63gh2tg4	814	8	.	.	.
cord-310847-63gh2tg4	815	1	Chronic	chronic	JJ
cord-310847-63gh2tg4	815	2	beryllium	beryllium	NN
cord-310847-63gh2tg4	815	3	disease	disease	NN
cord-310847-63gh2tg4	815	4	and	and	CC
cord-310847-63gh2tg4	815	5	Lys96Glu	Lys96Glu	NNP
cord-310847-63gh2tg4	815	6	mutation	mutation	NN
cord-310847-63gh2tg4	815	7	in	in	IN
cord-310847-63gh2tg4	815	8	HLA	HLA	NNP
cord-310847-63gh2tg4	815	9	-	-	HYPH
cord-310847-63gh2tg4	815	10	DPB1	DPB1	NNP
cord-310847-63gh2tg4	815	11	.	.	.
cord-310847-63gh2tg4	816	1	Chronic	chronic	JJ
cord-310847-63gh2tg4	816	2	beryllium	beryllium	NN
cord-310847-63gh2tg4	816	3	disease	disease	NN
cord-310847-63gh2tg4	816	4	(	(	-LRB-
cord-310847-63gh2tg4	816	5	CBD	CBD	NNP
cord-310847-63gh2tg4	816	6	)	)	-RRB-
cord-310847-63gh2tg4	816	7	is	be	VBZ
cord-310847-63gh2tg4	816	8	a	a	DT
cord-310847-63gh2tg4	816	9	hypersensitivity	hypersensitivity	NN
cord-310847-63gh2tg4	816	10	disorder	disorder	NN
cord-310847-63gh2tg4	816	11	that	that	WDT
cord-310847-63gh2tg4	816	12	affects	affect	VBZ
cord-310847-63gh2tg4	816	13	2	2	CD
cord-310847-63gh2tg4	816	14	-	-	SYM
cord-310847-63gh2tg4	816	15	16	16	CD
cord-310847-63gh2tg4	816	16	%	%	NN
cord-310847-63gh2tg4	816	17	of	of	IN
cord-310847-63gh2tg4	816	18	workers	worker	NNS
cord-310847-63gh2tg4	816	19	professionally	professionally	RB
cord-310847-63gh2tg4	816	20	exposed	expose	VBN
cord-310847-63gh2tg4	816	21	to	to	IN
cord-310847-63gh2tg4	816	22	berillium	berillium	NN
cord-310847-63gh2tg4	816	23	in	in	IN
cord-310847-63gh2tg4	816	24	the	the	DT
cord-310847-63gh2tg4	816	25	workplace	workplace	NN
cord-310847-63gh2tg4	816	26	.	.	.
cord-310847-63gh2tg4	817	1	CBD	CBD	NNP
cord-310847-63gh2tg4	817	2	is	be	VBZ
cord-310847-63gh2tg4	817	3	characterized	characterize	VBN
cord-310847-63gh2tg4	817	4	by	by	IN
cord-310847-63gh2tg4	817	5	a	a	DT
cord-310847-63gh2tg4	817	6	granulomatous	granulomatous	JJ
cord-310847-63gh2tg4	817	7	inflammation	inflammation	NN
cord-310847-63gh2tg4	817	8	and	and	CC
cord-310847-63gh2tg4	817	9	accumulation	accumulation	NN
cord-310847-63gh2tg4	817	10	of	of	IN
cord-310847-63gh2tg4	817	11	beryllium	beryllium	NN
cord-310847-63gh2tg4	817	12	-	-	HYPH
cord-310847-63gh2tg4	817	13	specific	specific	JJ
cord-310847-63gh2tg4	817	14	CD4	CD4	NNP
cord-310847-63gh2tg4	817	15	+	+	CC
cord-310847-63gh2tg4	817	16	T	t	NN
cord-310847-63gh2tg4	817	17	cells	cell	NNS
cord-310847-63gh2tg4	817	18	in	in	IN
cord-310847-63gh2tg4	817	19	the	the	DT
cord-310847-63gh2tg4	817	20	lung	lung	NN
cord-310847-63gh2tg4	817	21	.	.	.
cord-310847-63gh2tg4	818	1	242	242	CD
cord-310847-63gh2tg4	819	1	The	the	DT
cord-310847-63gh2tg4	819	2	susceptibility	susceptibility	NN
cord-310847-63gh2tg4	819	3	to	to	IN
cord-310847-63gh2tg4	819	4	this	this	DT
cord-310847-63gh2tg4	819	5	disease	disease	NN
cord-310847-63gh2tg4	819	6	depends	depend	VBZ
cord-310847-63gh2tg4	819	7	on	on	IN
cord-310847-63gh2tg4	819	8	both	both	DT
cord-310847-63gh2tg4	819	9	genetic	genetic	JJ
cord-310847-63gh2tg4	819	10	factors	factor	NNS
cord-310847-63gh2tg4	819	11	(	(	-LRB-
cord-310847-63gh2tg4	819	12	genetic	genetic	JJ
cord-310847-63gh2tg4	819	13	susceptibility	susceptibility	NN
cord-310847-63gh2tg4	819	14	)	)	-RRB-
cord-310847-63gh2tg4	819	15	and	and	CC
cord-310847-63gh2tg4	819	16	the	the	DT
cord-310847-63gh2tg4	819	17	nature	nature	NN
cord-310847-63gh2tg4	819	18	of	of	IN
cord-310847-63gh2tg4	819	19	the	the	DT
cord-310847-63gh2tg4	819	20	exposure	exposure	NN
cord-310847-63gh2tg4	819	21	.	.	.
cord-310847-63gh2tg4	820	1	Genetic	genetic	JJ
cord-310847-63gh2tg4	820	2	analysis	analysis	NN
cord-310847-63gh2tg4	820	3	revealed	reveal	VBD
cord-310847-63gh2tg4	820	4	that	that	IN
cord-310847-63gh2tg4	820	5	a	a	DT
cord-310847-63gh2tg4	820	6	single	single	JJ
cord-310847-63gh2tg4	820	7	point	point	NN
cord-310847-63gh2tg4	820	8	mutation	mutation	NN
cord-310847-63gh2tg4	820	9	at	at	IN
cord-310847-63gh2tg4	820	10	the	the	DT
cord-310847-63gh2tg4	820	11	69th	69th	JJ
cord-310847-63gh2tg4	820	12	position	position	NN
cord-310847-63gh2tg4	820	13	of	of	IN
cord-310847-63gh2tg4	820	14	the	the	DT
cord-310847-63gh2tg4	820	15	human	human	JJ
cord-310847-63gh2tg4	820	16	leukocyte	leukocyte	NN
cord-310847-63gh2tg4	820	17	antigen	antigen	NN
cord-310847-63gh2tg4	820	18	(	(	-LRB-
cord-310847-63gh2tg4	820	19	HLA	HLA	NNP
cord-310847-63gh2tg4	820	20	)	)	-RRB-
cord-310847-63gh2tg4	820	21	class	class	NN
cord-310847-63gh2tg4	820	22	II	II	NNP
cord-310847-63gh2tg4	820	23	histocompatibility	histocompatibility	NN
cord-310847-63gh2tg4	820	24	antigen	antigen	NN
cord-310847-63gh2tg4	820	25	DP	dp	NN
cord-310847-63gh2tg4	820	26	β	β	NN
cord-310847-63gh2tg4	820	27	1	1	CD
cord-310847-63gh2tg4	820	28	chain	chain	NN
cord-310847-63gh2tg4	820	29	(	(	-LRB-
cord-310847-63gh2tg4	820	30	HLA	HLA	NNP
cord-310847-63gh2tg4	820	31	-	-	HYPH
cord-310847-63gh2tg4	820	32	DPB1	DPB1	NNP
cord-310847-63gh2tg4	820	33	)	)	-RRB-
cord-310847-63gh2tg4	820	34	,	,	,
cord-310847-63gh2tg4	820	35	where	where	WRB
cord-310847-63gh2tg4	820	36	lysine	lysine	NN
cord-310847-63gh2tg4	820	37	is	be	VBZ
cord-310847-63gh2tg4	820	38	substituted	substitute	VBN
cord-310847-63gh2tg4	820	39	by	by	IN
cord-310847-63gh2tg4	820	40	a	a	DT
cord-310847-63gh2tg4	820	41	glutamic	glutamic	NN
cord-310847-63gh2tg4	820	42	acid	acid	NN
cord-310847-63gh2tg4	820	43	,	,	,
cord-310847-63gh2tg4	820	44	makes	make	VBZ
cord-310847-63gh2tg4	820	45	the	the	DT
cord-310847-63gh2tg4	820	46	carriers	carrier	NNS
cord-310847-63gh2tg4	820	47	more	more	RBR
cord-310847-63gh2tg4	820	48	susceptible	susceptible	JJ
cord-310847-63gh2tg4	820	49	to	to	IN
cord-310847-63gh2tg4	820	50	CBD	CBD	NNP
cord-310847-63gh2tg4	820	51	.	.	.
cord-310847-63gh2tg4	821	1	It	-PRON-	PRP
cord-310847-63gh2tg4	821	2	has	have	VBZ
cord-310847-63gh2tg4	821	3	been	be	VBN
cord-310847-63gh2tg4	821	4	proposed	propose	VBN
cord-310847-63gh2tg4	821	5	that	that	IN
cord-310847-63gh2tg4	821	6	the	the	DT
cord-310847-63gh2tg4	821	7	K→E	K→E	NNP
cord-310847-63gh2tg4	821	8	point	point	NN
cord-310847-63gh2tg4	821	9	of	of	IN
cord-310847-63gh2tg4	821	10	enzymes	enzyme	NNS
cord-310847-63gh2tg4	821	11	,	,	,
cord-310847-63gh2tg4	821	12	or	or	CC
cord-310847-63gh2tg4	821	13	be	be	VB
cord-310847-63gh2tg4	821	14	related	relate	VBN
cord-310847-63gh2tg4	821	15	to	to	IN
cord-310847-63gh2tg4	821	16	metal	metal	NN
cord-310847-63gh2tg4	821	17	binding	binding	NN
cord-310847-63gh2tg4	821	18	.	.	.
cord-310847-63gh2tg4	822	1	In	in	IN
cord-310847-63gh2tg4	822	2	IDPs	IDPs	NNP
cord-310847-63gh2tg4	822	3	/	/	SYM
cord-310847-63gh2tg4	822	4	IDPRs	IDPRs	NNP
cord-310847-63gh2tg4	822	5	,	,	,
cord-310847-63gh2tg4	822	6	overabundance	overabundance	NN
cord-310847-63gh2tg4	822	7	of	of	IN
cord-310847-63gh2tg4	822	8	glutamic	glutamic	NN
cord-310847-63gh2tg4	822	9	acids	acid	NNS
cord-310847-63gh2tg4	822	10	defines	define	VBZ
cord-310847-63gh2tg4	822	11	the	the	DT
cord-310847-63gh2tg4	822	12	extended	extended	JJ
cord-310847-63gh2tg4	822	13	conformation	conformation	NN
cord-310847-63gh2tg4	822	14	of	of	IN
cord-310847-63gh2tg4	822	15	native	native	JJ
cord-310847-63gh2tg4	822	16	coils	coil	NNS
cord-310847-63gh2tg4	822	17	and	and	CC
cord-310847-63gh2tg4	822	18	native	native	JJ
cord-310847-63gh2tg4	822	19	pre	pre	JJ
cord-310847-63gh2tg4	822	20	-	-	JJ
cord-310847-63gh2tg4	822	21	molten	molten	JJ
cord-310847-63gh2tg4	822	22	globules	globule	NNS
cord-310847-63gh2tg4	822	23	.	.	.
cord-310847-63gh2tg4	823	1	Glutamic	glutamic	NN
cord-310847-63gh2tg4	823	2	acid	acid	NN
cord-310847-63gh2tg4	823	3	is	be	VBZ
cord-310847-63gh2tg4	823	4	an	an	DT
cord-310847-63gh2tg4	823	5	important	important	JJ
cord-310847-63gh2tg4	823	6	part	part	NN
cord-310847-63gh2tg4	823	7	of	of	IN
cord-310847-63gh2tg4	823	8	the	the	DT
cord-310847-63gh2tg4	823	9	PEST	PEST	NNP
cord-310847-63gh2tg4	823	10	motif	motif	NN
cord-310847-63gh2tg4	823	11	related	relate	VBN
cord-310847-63gh2tg4	823	12	to	to	IN
cord-310847-63gh2tg4	823	13	protein	protein	NN
cord-310847-63gh2tg4	823	14	degradation	degradation	NN
cord-310847-63gh2tg4	823	15	.	.	.
cord-310847-63gh2tg4	824	1	It	-PRON-	PRP
cord-310847-63gh2tg4	824	2	is	be	VBZ
cord-310847-63gh2tg4	824	3	crucial	crucial	JJ
cord-310847-63gh2tg4	824	4	for	for	IN
cord-310847-63gh2tg4	824	5	function	function	NN
cord-310847-63gh2tg4	824	6	of	of	IN
cord-310847-63gh2tg4	824	7	entropic	entropic	JJ
cord-310847-63gh2tg4	824	8	bristle	bristle	NN
cord-310847-63gh2tg4	824	9	domains	domain	NNS
cord-310847-63gh2tg4	824	10	and	and	CC
cord-310847-63gh2tg4	824	11	several	several	JJ
cord-310847-63gh2tg4	824	12	chaperones	chaperone	NNS
cord-310847-63gh2tg4	824	13	.	.	.
cord-310847-63gh2tg4	825	1	Stretches	stretch	NNS
cord-310847-63gh2tg4	825	2	of	of	IN
cord-310847-63gh2tg4	825	3	glutamic	glutamic	NN
cord-310847-63gh2tg4	825	4	acid	acid	NN
cord-310847-63gh2tg4	825	5	residues	residue	NNS
cord-310847-63gh2tg4	825	6	have	have	VBP
cord-310847-63gh2tg4	825	7	a	a	DT
cord-310847-63gh2tg4	825	8	lot	lot	NN
cord-310847-63gh2tg4	825	9	of	of	IN
cord-310847-63gh2tg4	825	10	specific	specific	JJ
cord-310847-63gh2tg4	825	11	functions	function	NNS
cord-310847-63gh2tg4	825	12	that	that	WDT
cord-310847-63gh2tg4	825	13	range	range	VBP
cord-310847-63gh2tg4	825	14	from	from	IN
cord-310847-63gh2tg4	825	15	unique	unique	JJ
cord-310847-63gh2tg4	825	16	metal	metal	NN
cord-310847-63gh2tg4	825	17	binding	bind	VBG
cord-310847-63gh2tg4	825	18	properties	property	NNS
cord-310847-63gh2tg4	825	19	of	of	IN
cord-310847-63gh2tg4	825	20	phytochelatins	phytochelatin	NNS
cord-310847-63gh2tg4	825	21	and	and	CC
cord-310847-63gh2tg4	825	22	bone	bone	NN
cord-310847-63gh2tg4	825	23	phosphoproteins	phosphoprotein	NNS
cord-310847-63gh2tg4	825	24	,	,	,
cord-310847-63gh2tg4	825	25	to	to	IN
cord-310847-63gh2tg4	825	26	regulation	regulation	NN
cord-310847-63gh2tg4	825	27	of	of	IN
cord-310847-63gh2tg4	825	28	cell	cell	NN
cord-310847-63gh2tg4	825	29	adhesion	adhesion	NN
cord-310847-63gh2tg4	825	30	and	and	CC
cord-310847-63gh2tg4	825	31	migration	migration	NN
cord-310847-63gh2tg4	825	32	,	,	,
cord-310847-63gh2tg4	825	33	to	to	IN
cord-310847-63gh2tg4	825	34	defining	define	VBG
cord-310847-63gh2tg4	825	35	specific	specific	JJ
cord-310847-63gh2tg4	825	36	immunochemical	immunochemical	JJ
cord-310847-63gh2tg4	825	37	reactivity	reactivity	NN
cord-310847-63gh2tg4	825	38	of	of	IN
cord-310847-63gh2tg4	825	39	several	several	JJ
cord-310847-63gh2tg4	825	40	antigens	antigen	NNS
cord-310847-63gh2tg4	825	41	.	.	.
cord-310847-63gh2tg4	826	1	No	no	DT
cord-310847-63gh2tg4	826	2	potential	potential	JJ
cord-310847-63gh2tg4	826	3	conflicts	conflict	NNS
cord-310847-63gh2tg4	826	4	of	of	IN
cord-310847-63gh2tg4	826	5	interest	interest	NN
cord-310847-63gh2tg4	826	6	were	be	VBD
cord-310847-63gh2tg4	826	7	disclosed	disclose	VBN
cord-310847-63gh2tg4	826	8	.	.	.
cord-310847-63gh2tg4	827	1	This	this	DT
cord-310847-63gh2tg4	827	2	review	review	NN
cord-310847-63gh2tg4	827	3	illustrates	illustrate	VBZ
cord-310847-63gh2tg4	827	4	that	that	IN
cord-310847-63gh2tg4	827	5	glutamic	glutamic	NN
cord-310847-63gh2tg4	827	6	acid	acid	NN
cord-310847-63gh2tg4	827	7	is	be	VBZ
cord-310847-63gh2tg4	827	8	differently	differently	RB
cord-310847-63gh2tg4	827	9	used	use	VBN
cord-310847-63gh2tg4	827	10	in	in	IN
cord-310847-63gh2tg4	827	11	ordered	order	VBN
cord-310847-63gh2tg4	827	12	proteins	protein	NNS
cord-310847-63gh2tg4	827	13	/	/	SYM
cord-310847-63gh2tg4	827	14	domains	domain	NNS
cord-310847-63gh2tg4	827	15	and	and	CC
cord-310847-63gh2tg4	827	16	in	in	IN
cord-310847-63gh2tg4	827	17	IDPs	IDPs	NNP
cord-310847-63gh2tg4	827	18	/	/	SYM
cord-310847-63gh2tg4	827	19	IDPRs	IDPRs	NNP
cord-310847-63gh2tg4	827	20	.	.	.
cord-310847-63gh2tg4	828	1	In	in	IN
cord-310847-63gh2tg4	828	2	ordered	order	VBN
cord-310847-63gh2tg4	828	3	proteins	protein	NNS
cord-310847-63gh2tg4	828	4	,	,	,
cord-310847-63gh2tg4	828	5	glutamic	glutamic	NN
cord-310847-63gh2tg4	828	6	acid	acid	NN
cord-310847-63gh2tg4	828	7	residues	residue	NNS
cord-310847-63gh2tg4	828	8	are	be	VBP
cord-310847-63gh2tg4	828	9	crucial	crucial	JJ
cord-310847-63gh2tg4	828	10	for	for	IN
cord-310847-63gh2tg4	828	11	protein	protein	NN
cord-310847-63gh2tg4	828	12	solubility	solubility	NN
cord-310847-63gh2tg4	828	13	and	and	CC
cord-310847-63gh2tg4	828	14	,	,	,
cord-310847-63gh2tg4	828	15	being	be	VBG
cord-310847-63gh2tg4	828	16	strategically	strategically	RB
cord-310847-63gh2tg4	828	17	placed	place	VBN
cord-310847-63gh2tg4	828	18	within	within	IN
cord-310847-63gh2tg4	828	19	protein	protein	NN
cord-310847-63gh2tg4	828	20	structure	structure	NN
cord-310847-63gh2tg4	828	21	,	,	,
cord-310847-63gh2tg4	828	22	play	play	VB
cord-310847-63gh2tg4	828	23	several	several	JJ
cord-310847-63gh2tg4	828	24	structure	structure	NN
cord-310847-63gh2tg4	828	25	-	-	HYPH
cord-310847-63gh2tg4	828	26	forming	form	VBG
cord-310847-63gh2tg4	828	27	and	and	CC
cord-310847-63gh2tg4	828	28	structure	structure	NN
cord-310847-63gh2tg4	828	29	-	-	HYPH
cord-310847-63gh2tg4	828	30	stabilizing	stabilize	VBG
cord-310847-63gh2tg4	828	31	roles	role	NNS
cord-310847-63gh2tg4	828	32	.	.	.
cord-310847-63gh2tg4	829	1	Here	here	RB
cord-310847-63gh2tg4	829	2	,	,	,
cord-310847-63gh2tg4	829	3	glutamic	glutamic	NN
cord-310847-63gh2tg4	829	4	acid	acid	NN
cord-310847-63gh2tg4	829	5	is	be	VBZ
cord-310847-63gh2tg4	829	6	involved	involve	VBN
cord-310847-63gh2tg4	829	7	in	in	IN
cord-310847-63gh2tg4	829	8	electrostatic	electrostatic	JJ
cord-310847-63gh2tg4	829	9	interactions	interaction	NNS
cord-310847-63gh2tg4	829	10	and	and	CC
cord-310847-63gh2tg4	829	11	hydrogen	hydrogen	NN
cord-310847-63gh2tg4	829	12	bond	bond	NN
cord-310847-63gh2tg4	829	13	formation	formation	NN
cord-310847-63gh2tg4	829	14	,	,	,
cord-310847-63gh2tg4	829	15	serves	serve	VBZ
cord-310847-63gh2tg4	829	16	as	as	IN
cord-310847-63gh2tg4	829	17	an	an	DT
cord-310847-63gh2tg4	829	18	important	important	JJ
cord-310847-63gh2tg4	829	19	α	α	NN
cord-310847-63gh2tg4	829	20	-	-	HYPH
cord-310847-63gh2tg4	829	21	helix	helix	NN
cord-310847-63gh2tg4	829	22	former	former	NN
cord-310847-63gh2tg4	829	23	,	,	,
cord-310847-63gh2tg4	829	24	and	and	CC
cord-310847-63gh2tg4	829	25	participates	participate	VBZ
cord-310847-63gh2tg4	829	26	in	in	IN
cord-310847-63gh2tg4	829	27	the	the	DT
cord-310847-63gh2tg4	829	28	α	α	NN
cord-310847-63gh2tg4	829	29	-	-	HYPH
cord-310847-63gh2tg4	829	30	helix	helix	NN
cord-310847-63gh2tg4	829	31	cap	cap	NN
cord-310847-63gh2tg4	829	32	formation	formation	NN
cord-310847-63gh2tg4	829	33	.	.	.
cord-310847-63gh2tg4	830	1	Glutamic	glutamic	NN
cord-310847-63gh2tg4	830	2	acid	acid	NN
cord-310847-63gh2tg4	830	3	is	be	VBZ
cord-310847-63gh2tg4	830	4	an	an	DT
cord-310847-63gh2tg4	830	5	important	important	JJ
cord-310847-63gh2tg4	830	6	functional	functional	JJ
cord-310847-63gh2tg4	830	7	residue	residue	NN
cord-310847-63gh2tg4	830	8	of	of	IN
cord-310847-63gh2tg4	830	9	ordered	order	VBN
cord-310847-63gh2tg4	830	10	proteins	protein	NNS
cord-310847-63gh2tg4	830	11	,	,	,
cord-310847-63gh2tg4	830	12	where	where	WRB
cord-310847-63gh2tg4	830	13	it	-PRON-	PRP
cord-310847-63gh2tg4	830	14	can	can	MD
cord-310847-63gh2tg4	830	15	be	be	VB
cord-310847-63gh2tg4	830	16	involved	involve	VBN
cord-310847-63gh2tg4	830	17	in	in	IN
cord-310847-63gh2tg4	830	18	the	the	DT
cord-310847-63gh2tg4	830	19	formation	formation	NN
cord-310847-63gh2tg4	830	20	of	of	IN
cord-310847-63gh2tg4	830	21	specific	specific	JJ
cord-310847-63gh2tg4	830	22	electrostatic	electrostatic	JJ
cord-310847-63gh2tg4	830	23	valves	valve	NNS
cord-310847-63gh2tg4	830	24	inside	inside	IN
cord-310847-63gh2tg4	830	25	the	the	DT
cord-310847-63gh2tg4	830	26	pores	pore	NNS
cord-310847-63gh2tg4	830	27	of	of	IN
cord-310847-63gh2tg4	830	28	ion	ion	NN
cord-310847-63gh2tg4	830	29	channels	channel	NNS
cord-310847-63gh2tg4	830	30	,	,	,
cord-310847-63gh2tg4	830	31	or	or	CC
cord-310847-63gh2tg4	830	32	can	can	MD
cord-310847-63gh2tg4	830	33	play	play	VB
cord-310847-63gh2tg4	830	34	unique	unique	JJ
cord-310847-63gh2tg4	830	35	catalytic	catalytic	JJ
cord-310847-63gh2tg4	830	36	roles	role	NNS
cord-310847-63gh2tg4	830	37	in	in	IN
cord-310847-63gh2tg4	830	38	the	the	DT
cord-310847-63gh2tg4	830	39	active	active	JJ
cord-310847-63gh2tg4	830	40	sites	site	NNS
cord-310847-63gh2tg4	830	41	Intrinsically	intrinsically	RB
cord-310847-63gh2tg4	830	42	disordered	disordered	JJ
cord-310847-63gh2tg4	830	43	proteins	protein	NNS
cord-310847-63gh2tg4	830	44	from	from	IN
cord-310847-63gh2tg4	830	45	A	a	NN
cord-310847-63gh2tg4	830	46	to	to	IN
cord-310847-63gh2tg4	830	47	Z	Z	NNP
cord-310847-63gh2tg4	830	48	Unstructural	Unstructural	NNP
cord-310847-63gh2tg4	830	49	biology	biology	NN
cord-310847-63gh2tg4	830	50	coming	come	VBG
cord-310847-63gh2tg4	830	51	of	of	IN
cord-310847-63gh2tg4	830	52	age	age	NN
cord-310847-63gh2tg4	830	53	Thousands	thousand	NNS
cord-310847-63gh2tg4	830	54	of	of	IN
cord-310847-63gh2tg4	830	55	proteins	protein	NNS
cord-310847-63gh2tg4	830	56	likely	likely	JJ
cord-310847-63gh2tg4	830	57	to	to	TO
cord-310847-63gh2tg4	830	58	have	have	VB
cord-310847-63gh2tg4	830	59	long	long	JJ
cord-310847-63gh2tg4	830	60	disordered	disordered	JJ
cord-310847-63gh2tg4	830	61	regions	region	NNS
cord-310847-63gh2tg4	831	1	Intrinsic	intrinsic	JJ
cord-310847-63gh2tg4	831	2	protein	protein	NN
cord-310847-63gh2tg4	831	3	disorder	disorder	NN
cord-310847-63gh2tg4	831	4	in	in	IN
cord-310847-63gh2tg4	831	5	complete	complete	JJ
cord-310847-63gh2tg4	831	6	genomes	genome	NNS
cord-310847-63gh2tg4	832	1	Why	why	WRB
cord-310847-63gh2tg4	832	2	are	be	VBP
cord-310847-63gh2tg4	832	3	"	"	``
cord-310847-63gh2tg4	832	4	natively	natively	RB
cord-310847-63gh2tg4	832	5	unfolded	unfold	VBN
cord-310847-63gh2tg4	832	6	"	"	''
cord-310847-63gh2tg4	832	7	proteins	protein	NNS
cord-310847-63gh2tg4	832	8	unstructured	unstructured	JJ
cord-310847-63gh2tg4	832	9	under	under	IN
cord-310847-63gh2tg4	832	10	physiologic	physiologic	JJ
cord-310847-63gh2tg4	832	11	conditions	condition	NNS
cord-310847-63gh2tg4	832	12	?	?	.
cord-310847-63gh2tg4	833	1	Prediction	prediction	NN
cord-310847-63gh2tg4	833	2	and	and	CC
cord-310847-63gh2tg4	833	3	functional	functional	JJ
cord-310847-63gh2tg4	833	4	analysis	analysis	NN
cord-310847-63gh2tg4	833	5	of	of	IN
cord-310847-63gh2tg4	833	6	native	native	JJ
cord-310847-63gh2tg4	833	7	disorder	disorder	NN
cord-310847-63gh2tg4	833	8	in	in	IN
cord-310847-63gh2tg4	833	9	proteins	protein	NNS
cord-310847-63gh2tg4	833	10	from	from	IN
cord-310847-63gh2tg4	833	11	the	the	DT
cord-310847-63gh2tg4	833	12	three	three	CD
cord-310847-63gh2tg4	833	13	kingdoms	kingdom	NNS
cord-310847-63gh2tg4	833	14	of	of	IN
cord-310847-63gh2tg4	833	15	life	life	NN
cord-310847-63gh2tg4	833	16	Orderly	orderly	JJ
cord-310847-63gh2tg4	833	17	order	order	NN
cord-310847-63gh2tg4	833	18	in	in	IN
cord-310847-63gh2tg4	833	19	protein	protein	NN
cord-310847-63gh2tg4	833	20	intrinsic	intrinsic	JJ
cord-310847-63gh2tg4	833	21	disorder	disorder	NN
cord-310847-63gh2tg4	833	22	distribution	distribution	NN
cord-310847-63gh2tg4	833	23	:	:	:
cord-310847-63gh2tg4	833	24	disorder	disorder	NN
cord-310847-63gh2tg4	833	25	in	in	IN
cord-310847-63gh2tg4	833	26	3500	3500	CD
cord-310847-63gh2tg4	833	27	proteomes	proteome	NNS
cord-310847-63gh2tg4	833	28	from	from	IN
cord-310847-63gh2tg4	833	29	viruses	virus	NNS
cord-310847-63gh2tg4	833	30	and	and	CC
cord-310847-63gh2tg4	833	31	the	the	DT
cord-310847-63gh2tg4	833	32	three	three	CD
cord-310847-63gh2tg4	833	33	domains	domain	NNS
cord-310847-63gh2tg4	833	34	of	of	IN
cord-310847-63gh2tg4	833	35	life	life	NN
cord-310847-63gh2tg4	834	1	Understanding	understand	VBG
cord-310847-63gh2tg4	834	2	protein	protein	NN
cord-310847-63gh2tg4	834	3	nonfolding	nonfolde	VBG
cord-310847-63gh2tg4	834	4	Intrinsically	intrinsically	RB
cord-310847-63gh2tg4	834	5	unstructured	unstructured	JJ
cord-310847-63gh2tg4	834	6	proteins	protein	NNS
cord-310847-63gh2tg4	834	7	:	:	:
cord-310847-63gh2tg4	834	8	re	re	IN
cord-310847-63gh2tg4	834	9	-	-	JJ
cord-310847-63gh2tg4	834	10	assessing	assess	VBG
cord-310847-63gh2tg4	834	11	the	the	DT
cord-310847-63gh2tg4	834	12	protein	protein	NN
cord-310847-63gh2tg4	834	13	structure	structure	NN
cord-310847-63gh2tg4	834	14	-	-	HYPH
cord-310847-63gh2tg4	834	15	function	function	NN
cord-310847-63gh2tg4	834	16	paradigm	paradigm	NN
cord-310847-63gh2tg4	834	17	Intrinsically	intrinsically	RB
cord-310847-63gh2tg4	834	18	disordered	disordered	JJ
cord-310847-63gh2tg4	834	19	protein	protein	NN
cord-310847-63gh2tg4	834	20	Intrinsically	intrinsically	RB
cord-310847-63gh2tg4	834	21	unstructured	unstructured	JJ
cord-310847-63gh2tg4	834	22	proteins	protein	NNS
cord-310847-63gh2tg4	834	23	Intrinsically	intrinsically	RB
cord-310847-63gh2tg4	834	24	unstructured	unstructured	JJ
cord-310847-63gh2tg4	834	25	proteins	protein	NNS
cord-310847-63gh2tg4	834	26	and	and	CC
cord-310847-63gh2tg4	834	27	their	-PRON-	PRP$
cord-310847-63gh2tg4	834	28	functions	function	NNS
cord-310847-63gh2tg4	834	29	Intrinsic	intrinsic	JJ
cord-310847-63gh2tg4	834	30	disorder	disorder	NN
cord-310847-63gh2tg4	834	31	in	in	IN
cord-310847-63gh2tg4	834	32	cell	cell	NN
cord-310847-63gh2tg4	834	33	-	-	HYPH
cord-310847-63gh2tg4	834	34	signaling	signal	VBG
cord-310847-63gh2tg4	834	35	and	and	CC
cord-310847-63gh2tg4	834	36	cancer	cancer	NN
cord-310847-63gh2tg4	834	37	-	-	HYPH
cord-310847-63gh2tg4	834	38	associated	associate	VBN
cord-310847-63gh2tg4	834	39	proteins	protein	NNS
cord-310847-63gh2tg4	835	1	Intrinsic	intrinsic	JJ
cord-310847-63gh2tg4	835	2	disorder	disorder	NN
cord-310847-63gh2tg4	835	3	and	and	CC
cord-310847-63gh2tg4	835	4	protein	protein	NN
cord-310847-63gh2tg4	835	5	function	function	NN
cord-310847-63gh2tg4	835	6	Natively	natively	RB
cord-310847-63gh2tg4	835	7	unfolded	unfold	VBD
cord-310847-63gh2tg4	835	8	proteins	protein	NNS
cord-310847-63gh2tg4	835	9	:	:	:
cord-310847-63gh2tg4	835	10	a	a	DT
cord-310847-63gh2tg4	835	11	point	point	NN
cord-310847-63gh2tg4	835	12	where	where	WRB
cord-310847-63gh2tg4	835	13	biology	biology	NN
cord-310847-63gh2tg4	835	14	waits	wait	VBZ
cord-310847-63gh2tg4	835	15	for	for	IN
cord-310847-63gh2tg4	835	16	physics	physics	NN
cord-310847-63gh2tg4	835	17	Showing	show	VBG
cord-310847-63gh2tg4	835	18	your	-PRON-	PRP$
cord-310847-63gh2tg4	835	19	ID	id	NN
cord-310847-63gh2tg4	835	20	:	:	:
cord-310847-63gh2tg4	835	21	intrinsic	intrinsic	JJ
cord-310847-63gh2tg4	835	22	disorder	disorder	NN
cord-310847-63gh2tg4	835	23	as	as	IN
cord-310847-63gh2tg4	835	24	an	an	DT
cord-310847-63gh2tg4	835	25	ID	ID	NNP
cord-310847-63gh2tg4	835	26	for	for	IN
cord-310847-63gh2tg4	835	27	recognition	recognition	NN
cord-310847-63gh2tg4	835	28	,	,	,
cord-310847-63gh2tg4	835	29	regulation	regulation	NN
cord-310847-63gh2tg4	835	30	and	and	CC
cord-310847-63gh2tg4	835	31	cell	cell	NN
cord-310847-63gh2tg4	835	32	signaling	signal	VBG
cord-310847-63gh2tg4	835	33	Flexible	flexible	JJ
cord-310847-63gh2tg4	835	34	nets	net	NNS
cord-310847-63gh2tg4	835	35	.	.	.
cord-310847-63gh2tg4	836	1	The	the	DT
cord-310847-63gh2tg4	836	2	roles	role	NNS
cord-310847-63gh2tg4	836	3	of	of	IN
cord-310847-63gh2tg4	836	4	intrinsic	intrinsic	JJ
cord-310847-63gh2tg4	836	5	disorder	disorder	NN
cord-310847-63gh2tg4	836	6	in	in	IN
cord-310847-63gh2tg4	836	7	protein	protein	NN
cord-310847-63gh2tg4	836	8	interaction	interaction	NN
cord-310847-63gh2tg4	836	9	networks	network	NNS
cord-310847-63gh2tg4	836	10	Functional	functional	JJ
cord-310847-63gh2tg4	836	11	anthology	anthology	NN
cord-310847-63gh2tg4	836	12	of	of	IN
cord-310847-63gh2tg4	836	13	intrinsic	intrinsic	JJ
cord-310847-63gh2tg4	836	14	disorder	disorder	NN
cord-310847-63gh2tg4	836	15	.	.	.
cord-310847-63gh2tg4	837	1	1	1	LS
cord-310847-63gh2tg4	837	2	.	.	.
cord-310847-63gh2tg4	838	1	Biological	biological	JJ
cord-310847-63gh2tg4	838	2	processes	process	NNS
cord-310847-63gh2tg4	838	3	and	and	CC
cord-310847-63gh2tg4	838	4	functions	function	NNS
cord-310847-63gh2tg4	838	5	of	of	IN
cord-310847-63gh2tg4	838	6	proteins	protein	NNS
cord-310847-63gh2tg4	838	7	with	with	IN
cord-310847-63gh2tg4	838	8	long	long	JJ
cord-310847-63gh2tg4	838	9	disordered	disordered	JJ
cord-310847-63gh2tg4	838	10	regions	region	NNS
cord-310847-63gh2tg4	838	11	Functional	functional	JJ
cord-310847-63gh2tg4	838	12	anthology	anthology	NN
cord-310847-63gh2tg4	838	13	of	of	IN
cord-310847-63gh2tg4	838	14	intrinsic	intrinsic	JJ
cord-310847-63gh2tg4	838	15	disorder	disorder	NN
cord-310847-63gh2tg4	838	16	.	.	.
cord-310847-63gh2tg4	839	1	2	2	LS
cord-310847-63gh2tg4	839	2	.	.	.
cord-310847-63gh2tg4	840	1	Cellular	cellular	JJ
cord-310847-63gh2tg4	840	2	components	component	NNS
cord-310847-63gh2tg4	840	3	,	,	,
cord-310847-63gh2tg4	840	4	domains	domain	NNS
cord-310847-63gh2tg4	840	5	,	,	,
cord-310847-63gh2tg4	840	6	technical	technical	JJ
cord-310847-63gh2tg4	840	7	terms	term	NNS
cord-310847-63gh2tg4	840	8	,	,	,
cord-310847-63gh2tg4	840	9	developmental	developmental	JJ
cord-310847-63gh2tg4	840	10	processes	process	NNS
cord-310847-63gh2tg4	840	11	,	,	,
cord-310847-63gh2tg4	840	12	and	and	CC
cord-310847-63gh2tg4	840	13	coding	code	VBG
cord-310847-63gh2tg4	840	14	sequence	sequence	NN
cord-310847-63gh2tg4	840	15	diversities	diversity	NNS
cord-310847-63gh2tg4	840	16	correlated	correlate	VBN
cord-310847-63gh2tg4	840	17	with	with	IN
cord-310847-63gh2tg4	840	18	long	long	JJ
cord-310847-63gh2tg4	840	19	disordered	disordered	JJ
cord-310847-63gh2tg4	840	20	regions	region	NNS
cord-310847-63gh2tg4	840	21	Toward	toward	IN
cord-310847-63gh2tg4	840	22	a	a	DT
cord-310847-63gh2tg4	840	23	quantitative	quantitative	JJ
cord-310847-63gh2tg4	840	24	theory	theory	NN
cord-310847-63gh2tg4	840	25	of	of	IN
cord-310847-63gh2tg4	840	26	intrinsically	intrinsically	RB
cord-310847-63gh2tg4	840	27	disordered	disordered	JJ
cord-310847-63gh2tg4	840	28	proteins	protein	NNS
cord-310847-63gh2tg4	840	29	and	and	CC
cord-310847-63gh2tg4	840	30	their	-PRON-	PRP$
cord-310847-63gh2tg4	840	31	function	function	NN
cord-310847-63gh2tg4	841	1	The	the	DT
cord-310847-63gh2tg4	841	2	role	role	NN
cord-310847-63gh2tg4	841	3	of	of	IN
cord-310847-63gh2tg4	841	4	disorder	disorder	NN
cord-310847-63gh2tg4	841	5	in	in	IN
cord-310847-63gh2tg4	841	6	interaction	interaction	NN
cord-310847-63gh2tg4	841	7	networks	network	NNS
cord-310847-63gh2tg4	841	8	:	:	:
cord-310847-63gh2tg4	841	9	a	a	DT
cord-310847-63gh2tg4	841	10	structural	structural	JJ
cord-310847-63gh2tg4	841	11	analysis	analysis	NN
cord-310847-63gh2tg4	841	12	Flexible	Flexible	NNP
cord-310847-63gh2tg4	841	13	nets	net	NNS
cord-310847-63gh2tg4	841	14	:	:	:
cord-310847-63gh2tg4	841	15	disorder	disorder	NN
cord-310847-63gh2tg4	841	16	and	and	CC
cord-310847-63gh2tg4	841	17	induced	induce	VBN
cord-310847-63gh2tg4	841	18	fit	fit	JJ
cord-310847-63gh2tg4	841	19	in	in	IN
cord-310847-63gh2tg4	841	20	the	the	DT
cord-310847-63gh2tg4	841	21	associations	association	NNS
cord-310847-63gh2tg4	841	22	of	of	IN
cord-310847-63gh2tg4	841	23	p53	p53	NN
cord-310847-63gh2tg4	841	24	and	and	CC
cord-310847-63gh2tg4	841	25	14	14	CD
cord-310847-63gh2tg4	841	26	-	-	SYM
cord-310847-63gh2tg4	841	27	3	3	CD
cord-310847-63gh2tg4	841	28	-	-	SYM
cord-310847-63gh2tg4	841	29	3	3	CD
cord-310847-63gh2tg4	841	30	with	with	IN
cord-310847-63gh2tg4	841	31	their	-PRON-	PRP$
cord-310847-63gh2tg4	841	32	partners	partner	NNS
cord-310847-63gh2tg4	841	33	Linking	link	VBG
cord-310847-63gh2tg4	841	34	folding	fold	VBG
cord-310847-63gh2tg4	841	35	and	and	CC
cord-310847-63gh2tg4	841	36	binding	bind	VBG
cord-310847-63gh2tg4	841	37	Abundance	abundance	NN
cord-310847-63gh2tg4	841	38	of	of	IN
cord-310847-63gh2tg4	841	39	intrinsic	intrinsic	JJ
cord-310847-63gh2tg4	841	40	disorder	disorder	NN
cord-310847-63gh2tg4	841	41	in	in	IN
cord-310847-63gh2tg4	841	42	protein	protein	NN
cord-310847-63gh2tg4	841	43	associated	associate	VBN
cord-310847-63gh2tg4	841	44	with	with	IN
cord-310847-63gh2tg4	841	45	cardiovascular	cardiovascular	JJ
cord-310847-63gh2tg4	841	46	disease	disease	NN
cord-310847-63gh2tg4	841	47	Functional	functional	JJ
cord-310847-63gh2tg4	841	48	anthology	anthology	NN
cord-310847-63gh2tg4	841	49	of	of	IN
cord-310847-63gh2tg4	841	50	intrinsic	intrinsic	JJ
cord-310847-63gh2tg4	841	51	disorder	disorder	NN
cord-310847-63gh2tg4	841	52	.	.	.
cord-310847-63gh2tg4	842	1	3	3	LS
cord-310847-63gh2tg4	842	2	.	.	.
cord-310847-63gh2tg4	843	1	Ligands	Ligands	NNP
cord-310847-63gh2tg4	843	2	,	,	,
cord-310847-63gh2tg4	843	3	post	post	JJ
cord-310847-63gh2tg4	843	4	-	-	JJ
cord-310847-63gh2tg4	843	5	translational	translational	JJ
cord-310847-63gh2tg4	843	6	modifications	modification	NNS
cord-310847-63gh2tg4	843	7	,	,	,
cord-310847-63gh2tg4	843	8	and	and	CC
cord-310847-63gh2tg4	843	9	diseases	disease	NNS
cord-310847-63gh2tg4	843	10	associated	associate	VBN
cord-310847-63gh2tg4	843	11	with	with	IN
cord-310847-63gh2tg4	843	12	intrinsically	intrinsically	RB
cord-310847-63gh2tg4	843	13	disordered	disordered	JJ
cord-310847-63gh2tg4	843	14	proteins	protein	NNS
cord-310847-63gh2tg4	843	15	Intrinsically	intrinsically	RB
cord-310847-63gh2tg4	843	16	disordered	disordered	JJ
cord-310847-63gh2tg4	843	17	proteins	protein	NNS
cord-310847-63gh2tg4	843	18	in	in	IN
cord-310847-63gh2tg4	843	19	human	human	JJ
cord-310847-63gh2tg4	843	20	diseases	disease	NNS
cord-310847-63gh2tg4	843	21	:	:	:
cord-310847-63gh2tg4	843	22	introducing	introduce	VBG
cord-310847-63gh2tg4	843	23	the	the	DT
cord-310847-63gh2tg4	843	24	D2	d2	NN
cord-310847-63gh2tg4	843	25	concept	concept	NN
cord-310847-63gh2tg4	843	26	Unfoldomics	Unfoldomics	NNP
cord-310847-63gh2tg4	843	27	of	of	IN
cord-310847-63gh2tg4	843	28	human	human	JJ
cord-310847-63gh2tg4	843	29	genetic	genetic	JJ
cord-310847-63gh2tg4	843	30	diseases	disease	NNS
cord-310847-63gh2tg4	843	31	:	:	:
cord-310847-63gh2tg4	843	32	illustrative	illustrative	JJ
cord-310847-63gh2tg4	843	33	examples	example	NNS
cord-310847-63gh2tg4	843	34	of	of	IN
cord-310847-63gh2tg4	843	35	ordered	order	VBN
cord-310847-63gh2tg4	843	36	and	and	CC
cord-310847-63gh2tg4	843	37	intrinsically	intrinsically	RB
cord-310847-63gh2tg4	843	38	disordered	disordered	JJ
cord-310847-63gh2tg4	843	39	members	member	NNS
cord-310847-63gh2tg4	843	40	of	of	IN
cord-310847-63gh2tg4	843	41	the	the	DT
cord-310847-63gh2tg4	843	42	human	human	JJ
cord-310847-63gh2tg4	843	43	diseasome	diseasome	NNP
cord-310847-63gh2tg4	843	44	Unfoldomics	Unfoldomics	NNP
cord-310847-63gh2tg4	843	45	of	of	IN
cord-310847-63gh2tg4	843	46	human	human	JJ
cord-310847-63gh2tg4	843	47	diseases	disease	NNS
cord-310847-63gh2tg4	843	48	:	:	:
cord-310847-63gh2tg4	843	49	linking	link	VBG
cord-310847-63gh2tg4	843	50	protein	protein	NN
cord-310847-63gh2tg4	843	51	intrinsic	intrinsic	JJ
cord-310847-63gh2tg4	843	52	disorder	disorder	NN
cord-310847-63gh2tg4	843	53	with	with	IN
cord-310847-63gh2tg4	843	54	diseases	disease	NNS
cord-310847-63gh2tg4	843	55	Protein	Protein	NNP
cord-310847-63gh2tg4	843	56	disorder	disorder	NN
cord-310847-63gh2tg4	843	57	in	in	IN
cord-310847-63gh2tg4	843	58	the	the	DT
cord-310847-63gh2tg4	843	59	human	human	JJ
cord-310847-63gh2tg4	843	60	diseasome	diseasome	NN
cord-310847-63gh2tg4	843	61	:	:	:
cord-310847-63gh2tg4	843	62	unfoldomics	unfoldomics	NNP
cord-310847-63gh2tg4	843	63	of	of	IN
cord-310847-63gh2tg4	843	64	human	human	JJ
cord-310847-63gh2tg4	843	65	genetic	genetic	JJ
cord-310847-63gh2tg4	843	66	diseases	disease	NNS
cord-310847-63gh2tg4	844	1	Coupled	coupled	JJ
cord-310847-63gh2tg4	844	2	folding	folding	NN
cord-310847-63gh2tg4	844	3	and	and	CC
cord-310847-63gh2tg4	844	4	binding	bind	VBG
cord-310847-63gh2tg4	844	5	with	with	IN
cord-310847-63gh2tg4	844	6	alpha	alpha	NN
cord-310847-63gh2tg4	844	7	-	-	HYPH
cord-310847-63gh2tg4	844	8	helix	helix	NN
cord-310847-63gh2tg4	844	9	-	-	HYPH
cord-310847-63gh2tg4	844	10	forming	form	VBG
cord-310847-63gh2tg4	844	11	molecular	molecular	JJ
cord-310847-63gh2tg4	844	12	recognition	recognition	NN
cord-310847-63gh2tg4	844	13	elements	element	NNS
cord-310847-63gh2tg4	844	14	Analysis	Analysis	NNP
cord-310847-63gh2tg4	844	15	of	of	IN
cord-310847-63gh2tg4	844	16	molecular	molecular	JJ
cord-310847-63gh2tg4	844	17	recognition	recognition	NN
cord-310847-63gh2tg4	844	18	features	feature	NNS
cord-310847-63gh2tg4	844	19	(	(	-LRB-
cord-310847-63gh2tg4	844	20	MoRFs	morfs	NN
cord-310847-63gh2tg4	844	21	)	)	-RRB-
cord-310847-63gh2tg4	844	22	Characterization	characterization	NN
cord-310847-63gh2tg4	844	23	of	of	IN
cord-310847-63gh2tg4	844	24	molecular	molecular	JJ
cord-310847-63gh2tg4	844	25	recognition	recognition	NN
cord-310847-63gh2tg4	844	26	features	feature	NNS
cord-310847-63gh2tg4	844	27	,	,	,
cord-310847-63gh2tg4	844	28	MoRFs	MoRFs	NNP
cord-310847-63gh2tg4	844	29	,	,	,
cord-310847-63gh2tg4	844	30	and	and	CC
cord-310847-63gh2tg4	844	31	their	-PRON-	PRP$
cord-310847-63gh2tg4	844	32	binding	bind	VBG
cord-310847-63gh2tg4	844	33	partners	partner	NNS
cord-310847-63gh2tg4	844	34	Prediction	Prediction	NNP
cord-310847-63gh2tg4	844	35	of	of	IN
cord-310847-63gh2tg4	844	36	protein	protein	NN
cord-310847-63gh2tg4	844	37	binding	bind	VBG
cord-310847-63gh2tg4	844	38	regions	region	NNS
cord-310847-63gh2tg4	844	39	in	in	IN
cord-310847-63gh2tg4	844	40	disordered	disordered	JJ
cord-310847-63gh2tg4	844	41	proteins	protein	NNS
cord-310847-63gh2tg4	844	42	ANCHOR	anchor	NN
cord-310847-63gh2tg4	844	43	:	:	:
cord-310847-63gh2tg4	844	44	web	web	NN
cord-310847-63gh2tg4	844	45	server	server	NN
cord-310847-63gh2tg4	844	46	for	for	IN
cord-310847-63gh2tg4	844	47	predicting	predict	VBG
cord-310847-63gh2tg4	844	48	protein	protein	NN
cord-310847-63gh2tg4	844	49	binding	bind	VBG
cord-310847-63gh2tg4	844	50	regions	region	NNS
cord-310847-63gh2tg4	844	51	in	in	IN
cord-310847-63gh2tg4	844	52	disordered	disordered	JJ
cord-310847-63gh2tg4	844	53	proteins	protein	NNS
cord-310847-63gh2tg4	844	54	Multitude	Multitude	NNP
cord-310847-63gh2tg4	844	55	of	of	IN
cord-310847-63gh2tg4	844	56	binding	bind	VBG
cord-310847-63gh2tg4	844	57	modes	mode	NNS
cord-310847-63gh2tg4	844	58	attainable	attainable	JJ
cord-310847-63gh2tg4	844	59	by	by	IN
cord-310847-63gh2tg4	844	60	intrinsically	intrinsically	RB
cord-310847-63gh2tg4	844	61	disordered	disordered	JJ
cord-310847-63gh2tg4	844	62	proteins	protein	NNS
cord-310847-63gh2tg4	844	63	:	:	:
cord-310847-63gh2tg4	844	64	a	a	DT
cord-310847-63gh2tg4	844	65	portrait	portrait	JJ
cord-310847-63gh2tg4	844	66	gallery	gallery	NN
cord-310847-63gh2tg4	844	67	of	of	IN
cord-310847-63gh2tg4	844	68	disorder	disorder	NN
cord-310847-63gh2tg4	844	69	-	-	HYPH
cord-310847-63gh2tg4	844	70	based	base	VBN
cord-310847-63gh2tg4	844	71	complexes	complex	NNS
cord-310847-63gh2tg4	844	72	Capping	capping	NN
cord-310847-63gh2tg4	844	73	and	and	CC
cord-310847-63gh2tg4	844	74	alpha	alpha	NN
cord-310847-63gh2tg4	844	75	-	-	HYPH
cord-310847-63gh2tg4	844	76	helix	helix	NN
cord-310847-63gh2tg4	844	77	stability	stability	NN
cord-310847-63gh2tg4	844	78	Helix	Helix	NNP
cord-310847-63gh2tg4	844	79	capping	cap	VBG
cord-310847-63gh2tg4	844	80	Helix	helix	NN
cord-310847-63gh2tg4	844	81	capping	capping	NN
cord-310847-63gh2tg4	844	82	in	in	IN
cord-310847-63gh2tg4	844	83	the	the	DT
cord-310847-63gh2tg4	844	84	GCN4	GCN4	NNP
cord-310847-63gh2tg4	844	85	leucine	leucine	NN
cord-310847-63gh2tg4	844	86	zipper	zipper	NN
cord-310847-63gh2tg4	844	87	Alpha	alpha	NN
cord-310847-63gh2tg4	844	88	helix	helix	NN
cord-310847-63gh2tg4	844	89	capping	cap	VBG
cord-310847-63gh2tg4	844	90	in	in	IN
cord-310847-63gh2tg4	844	91	synthetic	synthetic	JJ
cord-310847-63gh2tg4	844	92	model	model	NN
cord-310847-63gh2tg4	844	93	peptides	peptide	NNS
cord-310847-63gh2tg4	844	94	by	by	IN
cord-310847-63gh2tg4	844	95	reciprocal	reciprocal	JJ
cord-310847-63gh2tg4	844	96	side	side	NN
cord-310847-63gh2tg4	844	97	chain	chain	NN
cord-310847-63gh2tg4	844	98	-	-	HYPH
cord-310847-63gh2tg4	844	99	main	main	JJ
cord-310847-63gh2tg4	844	100	chain	chain	NN
cord-310847-63gh2tg4	844	101	interactions	interaction	NNS
cord-310847-63gh2tg4	844	102	:	:	:
cord-310847-63gh2tg4	844	103	evidence	evidence	NN
cord-310847-63gh2tg4	844	104	for	for	IN
cord-310847-63gh2tg4	844	105	an	an	DT
cord-310847-63gh2tg4	844	106	N	n	CD
cord-310847-63gh2tg4	844	107	terminal	terminal	NN
cord-310847-63gh2tg4	844	108	"	"	''
cord-310847-63gh2tg4	844	109	capping	cap	VBG
cord-310847-63gh2tg4	844	110	box	box	NN
cord-310847-63gh2tg4	844	111	Hydrophobic	hydrophobic	JJ
cord-310847-63gh2tg4	844	112	interactions	interaction	NNS
cord-310847-63gh2tg4	844	113	at	at	IN
cord-310847-63gh2tg4	844	114	the	the	DT
cord-310847-63gh2tg4	844	115	Ccap	Ccap	NNP
cord-310847-63gh2tg4	844	116	position	position	NN
cord-310847-63gh2tg4	844	117	of	of	IN
cord-310847-63gh2tg4	844	118	the	the	DT
cord-310847-63gh2tg4	844	119	C	c	NN
cord-310847-63gh2tg4	844	120	-	-	HYPH
cord-310847-63gh2tg4	844	121	capping	cap	VBG
cord-310847-63gh2tg4	844	122	motif	motif	NN
cord-310847-63gh2tg4	844	123	of	of	IN
cord-310847-63gh2tg4	844	124	alpha	alpha	NN
cord-310847-63gh2tg4	844	125	-	-	HYPH
cord-310847-63gh2tg4	844	126	helices	helix	NNS
cord-310847-63gh2tg4	844	127	Stabilization	stabilization	NN
cord-310847-63gh2tg4	844	128	of	of	IN
cord-310847-63gh2tg4	844	129	α	α	NN
cord-310847-63gh2tg4	844	130	-	-	HYPH
cord-310847-63gh2tg4	844	131	helical	helical	JJ
cord-310847-63gh2tg4	844	132	structures	structure	NNS
cord-310847-63gh2tg4	844	133	in	in	IN
cord-310847-63gh2tg4	844	134	short	short	JJ
cord-310847-63gh2tg4	844	135	peptides	peptide	NNS
cord-310847-63gh2tg4	844	136	via	via	IN
cord-310847-63gh2tg4	844	137	end	end	NN
cord-310847-63gh2tg4	844	138	capping	cap	VBG
cord-310847-63gh2tg4	844	139	Measuring	measure	VBG
cord-310847-63gh2tg4	844	140	and	and	CC
cord-310847-63gh2tg4	844	141	increasing	increase	VBG
cord-310847-63gh2tg4	844	142	protein	protein	NN
cord-310847-63gh2tg4	844	143	solubility	solubility	NN
cord-310847-63gh2tg4	845	1	The	the	DT
cord-310847-63gh2tg4	845	2	cyclic	cyclic	JJ
cord-310847-63gh2tg4	845	3	nucleotide	nucleotide	NN
cord-310847-63gh2tg4	845	4	-	-	HYPH
cord-310847-63gh2tg4	845	5	gated	gate	VBN
cord-310847-63gh2tg4	845	6	channels	channel	NNS
cord-310847-63gh2tg4	845	7	of	of	IN
cord-310847-63gh2tg4	845	8	vertebrate	vertebrate	JJ
cord-310847-63gh2tg4	845	9	photoreceptors	photoreceptor	NNS
cord-310847-63gh2tg4	845	10	and	and	CC
cord-310847-63gh2tg4	845	11	olfactory	olfactory	JJ
cord-310847-63gh2tg4	845	12	epithelium	epithelium	NN
cord-310847-63gh2tg4	845	13	Rat	Rat	NNP
cord-310847-63gh2tg4	845	14	hippocampal	hippocampal	JJ
cord-310847-63gh2tg4	845	15	neurons	neuron	NNS
cord-310847-63gh2tg4	845	16	express	express	VBP
cord-310847-63gh2tg4	845	17	genes	gene	NNS
cord-310847-63gh2tg4	845	18	for	for	IN
cord-310847-63gh2tg4	845	19	both	both	DT
cord-310847-63gh2tg4	845	20	rod	rod	NN
cord-310847-63gh2tg4	845	21	retinal	retinal	JJ
cord-310847-63gh2tg4	845	22	and	and	CC
cord-310847-63gh2tg4	845	23	olfactory	olfactory	JJ
cord-310847-63gh2tg4	845	24	cyclic	cyclic	JJ
cord-310847-63gh2tg4	845	25	nucleotide	nucleotide	NN
cord-310847-63gh2tg4	845	26	-	-	HYPH
cord-310847-63gh2tg4	845	27	gated	gate	VBN
cord-310847-63gh2tg4	845	28	channels	channel	NNS
cord-310847-63gh2tg4	845	29	:	:	:
cord-310847-63gh2tg4	845	30	novel	novel	JJ
cord-310847-63gh2tg4	845	31	targets	target	NNS
cord-310847-63gh2tg4	845	32	for	for	IN
cord-310847-63gh2tg4	845	33	cAMP	camp	NN
cord-310847-63gh2tg4	845	34	/	/	SYM
cord-310847-63gh2tg4	845	35	cGMP	cGMP	NNP
cord-310847-63gh2tg4	845	36	function	function	VBP
cord-310847-63gh2tg4	845	37	Functional	functional	JJ
cord-310847-63gh2tg4	845	38	expression	expression	NN
cord-310847-63gh2tg4	845	39	of	of	IN
cord-310847-63gh2tg4	845	40	the	the	DT
cord-310847-63gh2tg4	845	41	heteromeric	heteromeric	JJ
cord-310847-63gh2tg4	845	42	"	"	``
cord-310847-63gh2tg4	845	43	olfactory	olfactory	JJ
cord-310847-63gh2tg4	845	44	"	"	''
cord-310847-63gh2tg4	845	45	cyclic	cyclic	JJ
cord-310847-63gh2tg4	845	46	nucleotide	nucleotide	NN
cord-310847-63gh2tg4	845	47	-	-	HYPH
cord-310847-63gh2tg4	845	48	gated	gate	VBN
cord-310847-63gh2tg4	845	49	channel	channel	NN
cord-310847-63gh2tg4	845	50	in	in	IN
cord-310847-63gh2tg4	845	51	the	the	DT
cord-310847-63gh2tg4	845	52	hippocampus	hippocampus	NN
cord-310847-63gh2tg4	845	53	:	:	:
cord-310847-63gh2tg4	845	54	a	a	DT
cord-310847-63gh2tg4	845	55	potential	potential	JJ
cord-310847-63gh2tg4	845	56	effector	effector	NN
cord-310847-63gh2tg4	845	57	of	of	IN
cord-310847-63gh2tg4	845	58	synaptic	synaptic	JJ
cord-310847-63gh2tg4	845	59	plasticity	plasticity	NN
cord-310847-63gh2tg4	845	60	in	in	IN
cord-310847-63gh2tg4	845	61	brain	brain	NN
cord-310847-63gh2tg4	845	62	neurons	neuron	NNS
cord-310847-63gh2tg4	845	63	Molecular	molecular	JJ
cord-310847-63gh2tg4	845	64	and	and	CC
cord-310847-63gh2tg4	845	65	pharmacological	pharmacological	JJ
cord-310847-63gh2tg4	845	66	analysis	analysis	NN
cord-310847-63gh2tg4	845	67	of	of	IN
cord-310847-63gh2tg4	845	68	cyclic	cyclic	JJ
cord-310847-63gh2tg4	845	69	nucleotide	nucleotide	RB
cord-310847-63gh2tg4	845	70	-	-	HYPH
cord-310847-63gh2tg4	845	71	gated	gate	VBN
cord-310847-63gh2tg4	845	72	channel	channel	NN
cord-310847-63gh2tg4	845	73	function	function	NN
cord-310847-63gh2tg4	845	74	in	in	IN
cord-310847-63gh2tg4	845	75	the	the	DT
cord-310847-63gh2tg4	845	76	central	central	JJ
cord-310847-63gh2tg4	845	77	nervous	nervous	JJ
cord-310847-63gh2tg4	845	78	system	system	NN
cord-310847-63gh2tg4	846	1	Cyclic	cyclic	JJ
cord-310847-63gh2tg4	846	2	nucleotide	nucleotide	JJ
cord-310847-63gh2tg4	846	3	-	-	HYPH
cord-310847-63gh2tg4	846	4	gated	gate	VBN
cord-310847-63gh2tg4	846	5	channels	channel	NNS
cord-310847-63gh2tg4	846	6	:	:	:
cord-310847-63gh2tg4	846	7	an	an	DT
cord-310847-63gh2tg4	846	8	expanding	expand	VBG
cord-310847-63gh2tg4	846	9	new	new	JJ
cord-310847-63gh2tg4	846	10	family	family	NN
cord-310847-63gh2tg4	846	11	of	of	IN
cord-310847-63gh2tg4	846	12	ion	ion	NN
cord-310847-63gh2tg4	846	13	channels	channel	NNS
cord-310847-63gh2tg4	846	14	Molecular	Molecular	NNP
cord-310847-63gh2tg4	846	15	mechanisms	mechanism	NNS
cord-310847-63gh2tg4	846	16	of	of	IN
cord-310847-63gh2tg4	846	17	cyclic	cyclic	JJ
cord-310847-63gh2tg4	846	18	nucleotide	nucleotide	NN
cord-310847-63gh2tg4	846	19	-	-	HYPH
cord-310847-63gh2tg4	846	20	gated	gate	VBN
cord-310847-63gh2tg4	846	21	channels	channel	NNS
cord-310847-63gh2tg4	846	22	Structure	structure	NN
cord-310847-63gh2tg4	846	23	and	and	CC
cord-310847-63gh2tg4	846	24	function	function	NN
cord-310847-63gh2tg4	846	25	of	of	IN
cord-310847-63gh2tg4	846	26	cyclic	cyclic	JJ
cord-310847-63gh2tg4	846	27	nucleotide	nucleotide	RB
cord-310847-63gh2tg4	846	28	-	-	HYPH
cord-310847-63gh2tg4	846	29	gated	gate	VBN
cord-310847-63gh2tg4	846	30	channels	channel	NNS
cord-310847-63gh2tg4	847	1	Cyclic	cyclic	JJ
cord-310847-63gh2tg4	847	2	nucleotide	nucleotide	JJ
cord-310847-63gh2tg4	847	3	-	-	HYPH
cord-310847-63gh2tg4	847	4	gated	gate	VBN
cord-310847-63gh2tg4	847	5	channels	channel	NNS
cord-310847-63gh2tg4	847	6	.	.	.
cord-310847-63gh2tg4	848	1	Molecular	molecular	JJ
cord-310847-63gh2tg4	848	2	mechanisms	mechanism	NNS
cord-310847-63gh2tg4	848	3	of	of	IN
cord-310847-63gh2tg4	848	4	activation	activation	NN
cord-310847-63gh2tg4	848	5	Role	role	NN
cord-310847-63gh2tg4	848	6	of	of	IN
cord-310847-63gh2tg4	848	7	H5	H5	NNP
cord-310847-63gh2tg4	848	8	domain	domain	NN
cord-310847-63gh2tg4	848	9	in	in	IN
cord-310847-63gh2tg4	848	10	determining	determine	VBG
cord-310847-63gh2tg4	848	11	pore	pore	NN
cord-310847-63gh2tg4	848	12	diameter	diameter	NN
cord-310847-63gh2tg4	848	13	and	and	CC
cord-310847-63gh2tg4	848	14	ion	ion	NN
cord-310847-63gh2tg4	848	15	permeation	permeation	NN
cord-310847-63gh2tg4	848	16	through	through	IN
cord-310847-63gh2tg4	848	17	cyclic	cyclic	JJ
cord-310847-63gh2tg4	848	18	nucleotide	nucleotide	RB
cord-310847-63gh2tg4	848	19	-	-	HYPH
cord-310847-63gh2tg4	848	20	gated	gate	VBN
cord-310847-63gh2tg4	848	21	channels	channel	NNS
cord-310847-63gh2tg4	848	22	Identification	identification	NN
cord-310847-63gh2tg4	848	23	of	of	IN
cord-310847-63gh2tg4	848	24	an	an	DT
cord-310847-63gh2tg4	848	25	external	external	JJ
cord-310847-63gh2tg4	848	26	divalent	divalent	JJ
cord-310847-63gh2tg4	848	27	cation	cation	NN
cord-310847-63gh2tg4	848	28	-	-	HYPH
cord-310847-63gh2tg4	848	29	binding	bind	VBG
cord-310847-63gh2tg4	848	30	site	site	NN
cord-310847-63gh2tg4	848	31	in	in	IN
cord-310847-63gh2tg4	848	32	the	the	DT
cord-310847-63gh2tg4	848	33	pore	pore	NN
cord-310847-63gh2tg4	848	34	of	of	IN
cord-310847-63gh2tg4	848	35	a	a	DT
cord-310847-63gh2tg4	848	36	cGMP	cGMP	NNP
cord-310847-63gh2tg4	848	37	-	-	HYPH
cord-310847-63gh2tg4	848	38	activated	activate	VBN
cord-310847-63gh2tg4	848	39	channel	channel	NN
cord-310847-63gh2tg4	848	40	Suggestions	suggestion	NNS
cord-310847-63gh2tg4	848	41	for	for	IN
cord-310847-63gh2tg4	848	42	"	"	``
cord-310847-63gh2tg4	848	43	safe	safe	JJ
cord-310847-63gh2tg4	848	44	"	"	''
cord-310847-63gh2tg4	848	45	residue	residue	NN
cord-310847-63gh2tg4	848	46	substitutions	substitution	NNS
cord-310847-63gh2tg4	848	47	in	in	IN
cord-310847-63gh2tg4	848	48	site	site	NN
cord-310847-63gh2tg4	848	49	-	-	HYPH
cord-310847-63gh2tg4	848	50	directed	direct	VBN
cord-310847-63gh2tg4	848	51	mutagenesis	mutagenesis	NN
cord-310847-63gh2tg4	848	52	Glutamate	glutamate	NN
cord-310847-63gh2tg4	848	53	as	as	IN
cord-310847-63gh2tg4	848	54	a	a	DT
cord-310847-63gh2tg4	848	55	neurotransmitter	neurotransmitter	NN
cord-310847-63gh2tg4	848	56	in	in	IN
cord-310847-63gh2tg4	848	57	the	the	DT
cord-310847-63gh2tg4	848	58	brain	brain	NN
cord-310847-63gh2tg4	848	59	:	:	:
cord-310847-63gh2tg4	848	60	review	review	NN
cord-310847-63gh2tg4	848	61	of	of	IN
cord-310847-63gh2tg4	848	62	physiology	physiology	NN
cord-310847-63gh2tg4	848	63	and	and	CC
cord-310847-63gh2tg4	848	64	pathology	pathology	NN
cord-310847-63gh2tg4	848	65	Glutamate	glutamate	NN
cord-310847-63gh2tg4	848	66	:	:	:
cord-310847-63gh2tg4	848	67	its	-PRON-	PRP$
cord-310847-63gh2tg4	848	68	role	role	NN
cord-310847-63gh2tg4	848	69	in	in	IN
cord-310847-63gh2tg4	848	70	learning	learning	NN
cord-310847-63gh2tg4	848	71	,	,	,
cord-310847-63gh2tg4	848	72	memory	memory	NN
cord-310847-63gh2tg4	848	73	,	,	,
cord-310847-63gh2tg4	848	74	and	and	CC
cord-310847-63gh2tg4	848	75	the	the	DT
cord-310847-63gh2tg4	848	76	aging	age	VBG
cord-310847-63gh2tg4	848	77	brain	brain	NN
cord-310847-63gh2tg4	848	78	Imaging	Imaging	NNP
cord-310847-63gh2tg4	848	79	extrasynaptic	extrasynaptic	JJ
cord-310847-63gh2tg4	848	80	glutamate	glutamate	NN
cord-310847-63gh2tg4	848	81	dynamics	dynamic	NNS
cord-310847-63gh2tg4	848	82	in	in	IN
cord-310847-63gh2tg4	848	83	the	the	DT
cord-310847-63gh2tg4	848	84	brain	brain	NN
cord-310847-63gh2tg4	848	85	Molecular	molecular	JJ
cord-310847-63gh2tg4	848	86	pharmacology	pharmacology	NN
cord-310847-63gh2tg4	848	87	of	of	IN
cord-310847-63gh2tg4	848	88	glutamate	glutamate	NN
cord-310847-63gh2tg4	848	89	transporters	transporter	NNS
cord-310847-63gh2tg4	848	90	,	,	,
cord-310847-63gh2tg4	848	91	EAATs	eaat	NNS
cord-310847-63gh2tg4	848	92	and	and	CC
cord-310847-63gh2tg4	848	93	VGLUTs	vglut	NNS
cord-310847-63gh2tg4	848	94	Glutamatemediated	glutamatemediate	VBN
cord-310847-63gh2tg4	848	95	excitotoxicity	excitotoxicity	NN
cord-310847-63gh2tg4	848	96	and	and	CC
cord-310847-63gh2tg4	848	97	neurodegeneration	neurodegeneration	NN
cord-310847-63gh2tg4	848	98	in	in	IN
cord-310847-63gh2tg4	848	99	Alzheimer	Alzheimer	NNP
cord-310847-63gh2tg4	848	100	's	's	POS
cord-310847-63gh2tg4	848	101	disease	disease	NN
cord-310847-63gh2tg4	848	102	L	l	NN
cord-310847-63gh2tg4	848	103	-	-	HYPH
cord-310847-63gh2tg4	848	104	phenylalanine	phenylalanine	NN
cord-310847-63gh2tg4	848	105	selectively	selectively	RB
cord-310847-63gh2tg4	848	106	depresses	depress	VBZ
cord-310847-63gh2tg4	848	107	currents	current	NNS
cord-310847-63gh2tg4	848	108	at	at	IN
cord-310847-63gh2tg4	848	109	glutamatergic	glutamatergic	JJ
cord-310847-63gh2tg4	848	110	excitatory	excitatory	JJ
cord-310847-63gh2tg4	848	111	synapses	synapsis	NNS
cord-310847-63gh2tg4	848	112	Long	long	JJ
cord-310847-63gh2tg4	848	113	-	-	HYPH
cord-310847-63gh2tg4	848	114	term	term	NN
cord-310847-63gh2tg4	848	115	changes	change	NNS
cord-310847-63gh2tg4	848	116	in	in	IN
cord-310847-63gh2tg4	848	117	glutamatergic	glutamatergic	JJ
cord-310847-63gh2tg4	848	118	synaptic	synaptic	JJ
cord-310847-63gh2tg4	848	119	transmission	transmission	NN
cord-310847-63gh2tg4	848	120	in	in	IN
cord-310847-63gh2tg4	848	121	phenylketonuria	phenylketonuria	NN
cord-310847-63gh2tg4	848	122	Stereochemistry	Stereochemistry	NNP
cord-310847-63gh2tg4	848	123	of	of	IN
cord-310847-63gh2tg4	848	124	polypeptide	polypeptide	NN
cord-310847-63gh2tg4	848	125	chain	chain	NN
cord-310847-63gh2tg4	848	126	configurations	configuration	NNS
cord-310847-63gh2tg4	849	1	Coulombic	coulombic	JJ
cord-310847-63gh2tg4	849	2	interactions	interaction	NNS
cord-310847-63gh2tg4	849	3	between	between	IN
cord-310847-63gh2tg4	849	4	partially	partially	RB
cord-310847-63gh2tg4	849	5	charged	charge	VBN
cord-310847-63gh2tg4	849	6	main	main	JJ
cord-310847-63gh2tg4	849	7	-	-	HYPH
cord-310847-63gh2tg4	849	8	chain	chain	NN
cord-310847-63gh2tg4	849	9	atoms	atom	NNS
cord-310847-63gh2tg4	849	10	not	not	RB
cord-310847-63gh2tg4	849	11	hydrogen	hydrogen	NN
cord-310847-63gh2tg4	849	12	-	-	HYPH
cord-310847-63gh2tg4	849	13	bonded	bond	VBN
cord-310847-63gh2tg4	849	14	to	to	IN
cord-310847-63gh2tg4	849	15	each	each	DT
cord-310847-63gh2tg4	849	16	other	other	JJ
cord-310847-63gh2tg4	849	17	influence	influence	NN
cord-310847-63gh2tg4	850	1	the	the	DT
cord-310847-63gh2tg4	850	2	conformations	conformation	NNS
cord-310847-63gh2tg4	850	3	of	of	IN
cord-310847-63gh2tg4	850	4	alpha	alpha	NN
cord-310847-63gh2tg4	850	5	-	-	HYPH
cord-310847-63gh2tg4	850	6	helices	helix	NNS
cord-310847-63gh2tg4	850	7	and	and	CC
cord-310847-63gh2tg4	850	8	antiparallel	antiparallel	VBP
cord-310847-63gh2tg4	850	9	beta	beta	NN
cord-310847-63gh2tg4	850	10	-	-	HYPH
cord-310847-63gh2tg4	850	11	sheet	sheet	NN
cord-310847-63gh2tg4	850	12	.	.	.
cord-310847-63gh2tg4	851	1	A	a	DT
cord-310847-63gh2tg4	851	2	new	new	JJ
cord-310847-63gh2tg4	851	3	method	method	NN
cord-310847-63gh2tg4	851	4	for	for	IN
cord-310847-63gh2tg4	851	5	analysing	analyse	VBG
cord-310847-63gh2tg4	851	6	the	the	DT
cord-310847-63gh2tg4	851	7	forces	force	NNS
cord-310847-63gh2tg4	851	8	between	between	IN
cord-310847-63gh2tg4	851	9	hydrogen	hydrogen	NN
cord-310847-63gh2tg4	851	10	bonding	bonding	NN
cord-310847-63gh2tg4	851	11	groups	group	NNS
cord-310847-63gh2tg4	851	12	in	in	IN
cord-310847-63gh2tg4	851	13	proteins	protein	NNS
cord-310847-63gh2tg4	851	14	includes	include	VBZ
cord-310847-63gh2tg4	851	15	all	all	PDT
cord-310847-63gh2tg4	851	16	the	the	DT
cord-310847-63gh2tg4	851	17	Coulombic	Coulombic	NNP
cord-310847-63gh2tg4	851	18	interactions	interaction	NNS
cord-310847-63gh2tg4	851	19	Revisiting	revisit	VBG
cord-310847-63gh2tg4	851	20	the	the	DT
cord-310847-63gh2tg4	851	21	Ramachandran	Ramachandran	NNP
cord-310847-63gh2tg4	851	22	plot	plot	NN
cord-310847-63gh2tg4	851	23	:	:	:
cord-310847-63gh2tg4	851	24	hard	hard	JJ
cord-310847-63gh2tg4	851	25	-	-	HYPH
cord-310847-63gh2tg4	851	26	sphere	sphere	NN
cord-310847-63gh2tg4	851	27	repulsion	repulsion	NN
cord-310847-63gh2tg4	851	28	,	,	,
cord-310847-63gh2tg4	851	29	electrostatics	electrostatic	NNS
cord-310847-63gh2tg4	851	30	,	,	,
cord-310847-63gh2tg4	851	31	and	and	CC
cord-310847-63gh2tg4	851	32	H	h	NN
cord-310847-63gh2tg4	851	33	-	-	HYPH
cord-310847-63gh2tg4	851	34	bonding	bonding	NN
cord-310847-63gh2tg4	851	35	in	in	IN
cord-310847-63gh2tg4	851	36	the	the	DT
cord-310847-63gh2tg4	851	37	alpha	alpha	NN
cord-310847-63gh2tg4	851	38	-	-	HYPH
cord-310847-63gh2tg4	851	39	helix	helix	NN
cord-310847-63gh2tg4	852	1	The	the	DT
cord-310847-63gh2tg4	852	2	Ramachandran	Ramachandran	NNP
cord-310847-63gh2tg4	852	3	plots	plot	NNS
cord-310847-63gh2tg4	852	4	of	of	IN
cord-310847-63gh2tg4	852	5	glycine	glycine	NN
cord-310847-63gh2tg4	852	6	and	and	CC
cord-310847-63gh2tg4	852	7	pre	pre	JJ
cord-310847-63gh2tg4	852	8	-	-	JJ
cord-310847-63gh2tg4	852	9	proline	proline	JJ
cord-310847-63gh2tg4	852	10	Satisfying	satisfy	VBG
cord-310847-63gh2tg4	852	11	hydrogen	hydrogen	NN
cord-310847-63gh2tg4	852	12	bonding	bonding	NN
cord-310847-63gh2tg4	852	13	potential	potential	NN
cord-310847-63gh2tg4	852	14	in	in	IN
cord-310847-63gh2tg4	852	15	proteins	protein	NNS
cord-310847-63gh2tg4	853	1	A	a	DT
cord-310847-63gh2tg4	853	2	helix	helix	NN
cord-310847-63gh2tg4	853	3	propensity	propensity	NN
cord-310847-63gh2tg4	853	4	scale	scale	NN
cord-310847-63gh2tg4	853	5	based	base	VBN
cord-310847-63gh2tg4	853	6	on	on	IN
cord-310847-63gh2tg4	853	7	experimental	experimental	JJ
cord-310847-63gh2tg4	853	8	studies	study	NNS
cord-310847-63gh2tg4	853	9	of	of	IN
cord-310847-63gh2tg4	853	10	peptides	peptide	NNS
cord-310847-63gh2tg4	853	11	and	and	CC
cord-310847-63gh2tg4	853	12	proteins	protein	NNS
cord-310847-63gh2tg4	854	1	The	the	DT
cord-310847-63gh2tg4	854	2	role	role	NN
cord-310847-63gh2tg4	854	3	of	of	IN
cord-310847-63gh2tg4	854	4	the	the	DT
cord-310847-63gh2tg4	854	5	alpha	alpha	NN
cord-310847-63gh2tg4	854	6	-	-	HYPH
cord-310847-63gh2tg4	854	7	helix	helix	NN
cord-310847-63gh2tg4	854	8	dipole	dipole	NN
cord-310847-63gh2tg4	854	9	in	in	IN
cord-310847-63gh2tg4	854	10	protein	protein	NN
cord-310847-63gh2tg4	854	11	function	function	NN
cord-310847-63gh2tg4	854	12	and	and	CC
cord-310847-63gh2tg4	854	13	structure	structure	NN
cord-310847-63gh2tg4	854	14	Effects	effect	NNS
cord-310847-63gh2tg4	854	15	of	of	IN
cord-310847-63gh2tg4	854	16	the	the	DT
cord-310847-63gh2tg4	854	17	alpha	alpha	NN
cord-310847-63gh2tg4	854	18	-	-	HYPH
cord-310847-63gh2tg4	854	19	helix	helix	NN
cord-310847-63gh2tg4	854	20	dipole	dipole	NN
cord-310847-63gh2tg4	854	21	upon	upon	IN
cord-310847-63gh2tg4	854	22	the	the	DT
cord-310847-63gh2tg4	854	23	functioning	functioning	NN
cord-310847-63gh2tg4	854	24	and	and	CC
cord-310847-63gh2tg4	854	25	structure	structure	NN
cord-310847-63gh2tg4	854	26	of	of	IN
cord-310847-63gh2tg4	854	27	proteins	protein	NNS
cord-310847-63gh2tg4	854	28	and	and	CC
cord-310847-63gh2tg4	855	1	peptides	peptides	NNP
cord-310847-63gh2tg4	855	2	Helix	Helix	NNP
cord-310847-63gh2tg4	855	3	signals	signal	NNS
cord-310847-63gh2tg4	855	4	in	in	IN
cord-310847-63gh2tg4	855	5	proteins	protein	NNS
cord-310847-63gh2tg4	856	1	Intrinsic	intrinsic	JJ
cord-310847-63gh2tg4	856	2	disorder	disorder	NN
cord-310847-63gh2tg4	856	3	-	-	HYPH
cord-310847-63gh2tg4	856	4	based	base	VBN
cord-310847-63gh2tg4	856	5	protein	protein	NN
cord-310847-63gh2tg4	856	6	interactions	interaction	NNS
cord-310847-63gh2tg4	856	7	and	and	CC
cord-310847-63gh2tg4	856	8	their	-PRON-	PRP$
cord-310847-63gh2tg4	856	9	modulators	modulator	NNS
cord-310847-63gh2tg4	856	10	Intrinsic	intrinsic	JJ
cord-310847-63gh2tg4	856	11	protein	protein	NN
cord-310847-63gh2tg4	856	12	disorder	disorder	NN
cord-310847-63gh2tg4	856	13	and	and	CC
cord-310847-63gh2tg4	856	14	protein	protein	NN
cord-310847-63gh2tg4	856	15	-	-	HYPH
cord-310847-63gh2tg4	856	16	protein	protein	NN
cord-310847-63gh2tg4	856	17	interactions	interaction	NNS
cord-310847-63gh2tg4	857	1	The	the	DT
cord-310847-63gh2tg4	857	2	expanding	expand	VBG
cord-310847-63gh2tg4	857	3	view	view	NN
cord-310847-63gh2tg4	857	4	of	of	IN
cord-310847-63gh2tg4	857	5	protein	protein	NN
cord-310847-63gh2tg4	857	6	-	-	HYPH
cord-310847-63gh2tg4	857	7	protein	protein	NN
cord-310847-63gh2tg4	857	8	interactions	interaction	NNS
cord-310847-63gh2tg4	857	9	:	:	:
cord-310847-63gh2tg4	857	10	complexes	complex	NNS
cord-310847-63gh2tg4	857	11	involving	involve	VBG
cord-310847-63gh2tg4	857	12	intrinsically	intrinsically	RB
cord-310847-63gh2tg4	857	13	disordered	disordered	JJ
cord-310847-63gh2tg4	857	14	proteins	protein	NNS
cord-310847-63gh2tg4	857	15	Limitations	limitation	NNS
cord-310847-63gh2tg4	857	16	of	of	IN
cord-310847-63gh2tg4	857	17	induced	induce	VBN
cord-310847-63gh2tg4	857	18	folding	fold	VBG
cord-310847-63gh2tg4	857	19	in	in	IN
cord-310847-63gh2tg4	857	20	molecular	molecular	JJ
cord-310847-63gh2tg4	857	21	recognition	recognition	NN
cord-310847-63gh2tg4	857	22	by	by	IN
cord-310847-63gh2tg4	857	23	intrinsically	intrinsically	RB
cord-310847-63gh2tg4	857	24	disordered	disordered	JJ
cord-310847-63gh2tg4	857	25	proteins	protein	NNS
cord-310847-63gh2tg4	858	1	Fuzzy	fuzzy	JJ
cord-310847-63gh2tg4	858	2	complexes	complex	NNS
cord-310847-63gh2tg4	858	3	:	:	:
cord-310847-63gh2tg4	858	4	polymorphism	polymorphism	NN
cord-310847-63gh2tg4	858	5	and	and	CC
cord-310847-63gh2tg4	858	6	structural	structural	JJ
cord-310847-63gh2tg4	858	7	disorder	disorder	NN
cord-310847-63gh2tg4	858	8	in	in	IN
cord-310847-63gh2tg4	858	9	protein	protein	NN
cord-310847-63gh2tg4	858	10	-	-	HYPH
cord-310847-63gh2tg4	858	11	protein	protein	NN
cord-310847-63gh2tg4	858	12	interactions	interaction	NNS
cord-310847-63gh2tg4	859	1	Preformed	preformed	JJ
cord-310847-63gh2tg4	859	2	structural	structural	JJ
cord-310847-63gh2tg4	859	3	elements	element	NNS
cord-310847-63gh2tg4	859	4	feature	feature	VBP
cord-310847-63gh2tg4	859	5	in	in	IN
cord-310847-63gh2tg4	859	6	partner	partner	NN
cord-310847-63gh2tg4	859	7	recognition	recognition	NN
cord-310847-63gh2tg4	859	8	by	by	IN
cord-310847-63gh2tg4	859	9	intrinsically	intrinsically	RB
cord-310847-63gh2tg4	859	10	unstructured	unstructured	JJ
cord-310847-63gh2tg4	859	11	proteins	protein	NNS
cord-310847-63gh2tg4	859	12	Pre	pre	JJ
cord-310847-63gh2tg4	859	13	-	-	JJ
cord-310847-63gh2tg4	859	14	structured	structured	JJ
cord-310847-63gh2tg4	859	15	motifs	motif	NNS
cord-310847-63gh2tg4	859	16	in	in	IN
cord-310847-63gh2tg4	859	17	the	the	DT
cord-310847-63gh2tg4	859	18	natively	natively	RB
cord-310847-63gh2tg4	859	19	unstructured	unstructured	JJ
cord-310847-63gh2tg4	859	20	preS1	pres1	NN
cord-310847-63gh2tg4	859	21	surface	surface	NN
cord-310847-63gh2tg4	859	22	antigen	antigen	NN
cord-310847-63gh2tg4	859	23	of	of	IN
cord-310847-63gh2tg4	859	24	hepatitis	hepatitis	NN
cord-310847-63gh2tg4	859	25	B	B	NNP
cord-310847-63gh2tg4	859	26	virus	virus	NN
cord-310847-63gh2tg4	860	1	Speeding	speed	VBG
cord-310847-63gh2tg4	860	2	molecular	molecular	JJ
cord-310847-63gh2tg4	860	3	recognition	recognition	NN
cord-310847-63gh2tg4	860	4	by	by	IN
cord-310847-63gh2tg4	860	5	using	use	VBG
cord-310847-63gh2tg4	860	6	the	the	DT
cord-310847-63gh2tg4	860	7	folding	folding	NN
cord-310847-63gh2tg4	860	8	funnel	funnel	NN
cord-310847-63gh2tg4	860	9	:	:	:
cord-310847-63gh2tg4	860	10	the	the	DT
cord-310847-63gh2tg4	860	11	fly	fly	VB
cord-310847-63gh2tg4	860	12	-	-	HYPH
cord-310847-63gh2tg4	860	13	casting	cast	VBG
cord-310847-63gh2tg4	860	14	mechanism	mechanism	NN
cord-310847-63gh2tg4	860	15	Kinetic	kinetic	JJ
cord-310847-63gh2tg4	860	16	advantage	advantage	NN
cord-310847-63gh2tg4	860	17	of	of	IN
cord-310847-63gh2tg4	860	18	intrinsically	intrinsically	RB
cord-310847-63gh2tg4	860	19	disordered	disordered	JJ
cord-310847-63gh2tg4	860	20	proteins	protein	NNS
cord-310847-63gh2tg4	860	21	in	in	IN
cord-310847-63gh2tg4	860	22	coupled	couple	VBN
cord-310847-63gh2tg4	860	23	folding	folding	NN
cord-310847-63gh2tg4	860	24	-	-	HYPH
cord-310847-63gh2tg4	860	25	binding	bind	VBG
cord-310847-63gh2tg4	860	26	process	process	NN
cord-310847-63gh2tg4	860	27	:	:	:
cord-310847-63gh2tg4	860	28	a	a	DT
cord-310847-63gh2tg4	860	29	critical	critical	JJ
cord-310847-63gh2tg4	860	30	assessment	assessment	NN
cord-310847-63gh2tg4	860	31	of	of	IN
cord-310847-63gh2tg4	860	32	the	the	DT
cord-310847-63gh2tg4	860	33	"	"	``
cord-310847-63gh2tg4	860	34	fly	fly	VB
cord-310847-63gh2tg4	860	35	-	-	HYPH
cord-310847-63gh2tg4	860	36	casting	cast	VBG
cord-310847-63gh2tg4	860	37	"	"	''
cord-310847-63gh2tg4	860	38	mechanism	mechanism	NN
cord-310847-63gh2tg4	860	39	Insights	insight	NNS
cord-310847-63gh2tg4	860	40	on	on	IN
cord-310847-63gh2tg4	860	41	the	the	DT
cord-310847-63gh2tg4	860	42	role	role	NN
cord-310847-63gh2tg4	860	43	of	of	IN
cord-310847-63gh2tg4	860	44	(	(	-LRB-
cord-310847-63gh2tg4	860	45	dis)order	dis)order	NN
cord-310847-63gh2tg4	860	46	from	from	IN
cord-310847-63gh2tg4	860	47	protein	protein	NN
cord-310847-63gh2tg4	860	48	-	-	HYPH
cord-310847-63gh2tg4	860	49	protein	protein	NN
cord-310847-63gh2tg4	860	50	interaction	interaction	NN
cord-310847-63gh2tg4	860	51	linear	linear	JJ
cord-310847-63gh2tg4	860	52	free	free	JJ
cord-310847-63gh2tg4	860	53	-	-	HYPH
cord-310847-63gh2tg4	860	54	energy	energy	NN
cord-310847-63gh2tg4	860	55	relationships	relationship	NNS
cord-310847-63gh2tg4	860	56	Protein	Protein	NNP
cord-310847-63gh2tg4	860	57	disorder	disorder	NN
cord-310847-63gh2tg4	860	58	and	and	CC
cord-310847-63gh2tg4	860	59	the	the	DT
cord-310847-63gh2tg4	860	60	evolution	evolution	NN
cord-310847-63gh2tg4	860	61	of	of	IN
cord-310847-63gh2tg4	860	62	molecular	molecular	JJ
cord-310847-63gh2tg4	860	63	recognition	recognition	NN
cord-310847-63gh2tg4	860	64	:	:	:
cord-310847-63gh2tg4	860	65	theory	theory	NN
cord-310847-63gh2tg4	860	66	,	,	,
cord-310847-63gh2tg4	860	67	predictions	prediction	NNS
cord-310847-63gh2tg4	860	68	and	and	CC
cord-310847-63gh2tg4	860	69	observations	observation	NNS
cord-310847-63gh2tg4	860	70	Intrinsic	intrinsic	JJ
cord-310847-63gh2tg4	860	71	disorder	disorder	NN
cord-310847-63gh2tg4	860	72	and	and	CC
cord-310847-63gh2tg4	860	73	functional	functional	JJ
cord-310847-63gh2tg4	860	74	proteomics	proteomic	NNS
cord-310847-63gh2tg4	860	75	Composition	Composition	NNP
cord-310847-63gh2tg4	860	76	Profiler	profiler	NN
cord-310847-63gh2tg4	860	77	:	:	:
cord-310847-63gh2tg4	860	78	a	a	DT
cord-310847-63gh2tg4	860	79	tool	tool	NN
cord-310847-63gh2tg4	860	80	for	for	IN
cord-310847-63gh2tg4	860	81	discovery	discovery	NN
cord-310847-63gh2tg4	860	82	and	and	CC
cord-310847-63gh2tg4	860	83	visualization	visualization	NN
cord-310847-63gh2tg4	860	84	of	of	IN
cord-310847-63gh2tg4	860	85	amino	amino	NN
cord-310847-63gh2tg4	860	86	acid	acid	NN
cord-310847-63gh2tg4	860	87	composition	composition	NN
cord-310847-63gh2tg4	860	88	differences	difference	NNS
cord-310847-63gh2tg4	860	89	DisProt	disprot	VBP
cord-310847-63gh2tg4	860	90	:	:	:
cord-310847-63gh2tg4	860	91	the	the	DT
cord-310847-63gh2tg4	860	92	Database	database	NN
cord-310847-63gh2tg4	860	93	of	of	IN
cord-310847-63gh2tg4	860	94	Disordered	disordered	JJ
cord-310847-63gh2tg4	860	95	Proteins	protein	NNS
cord-310847-63gh2tg4	861	1	The	the	DT
cord-310847-63gh2tg4	861	2	Protein	Protein	NNP
cord-310847-63gh2tg4	861	3	Data	Data	NNP
cord-310847-63gh2tg4	861	4	Bank	Bank	NNP
cord-310847-63gh2tg4	862	1	The	the	DT
cord-310847-63gh2tg4	862	2	Universal	Universal	NNP
cord-310847-63gh2tg4	862	3	Protein	Protein	NNP
cord-310847-63gh2tg4	862	4	Resource	Resource	NNP
cord-310847-63gh2tg4	862	5	(	(	-LRB-
cord-310847-63gh2tg4	862	6	UniProt	UniProt	NNP
cord-310847-63gh2tg4	862	7	)	)	-RRB-
cord-310847-63gh2tg4	862	8	Hydrophobicity	Hydrophobicity	NNP
cord-310847-63gh2tg4	862	9	regained	regain	VBD
cord-310847-63gh2tg4	862	10	Fine	fine	JJ
cord-310847-63gh2tg4	862	11	tuning	tune	VBG
cord-310847-63gh2tg4	862	12	the	the	DT
cord-310847-63gh2tg4	862	13	N	n	CD
cord-310847-63gh2tg4	862	14	-	-	HYPH
cord-310847-63gh2tg4	862	15	terminus	terminus	NN
cord-310847-63gh2tg4	862	16	of	of	IN
cord-310847-63gh2tg4	862	17	a	a	DT
cord-310847-63gh2tg4	862	18	calcium	calcium	NN
cord-310847-63gh2tg4	862	19	binding	bind	VBG
cord-310847-63gh2tg4	862	20	protein	protein	NN
cord-310847-63gh2tg4	862	21	:	:	:
cord-310847-63gh2tg4	862	22	alpha	alpha	NN
cord-310847-63gh2tg4	862	23	-	-	HYPH
cord-310847-63gh2tg4	862	24	lactalbumin	lactalbumin	NNP
cord-310847-63gh2tg4	862	25	Cation	Cation	NNP
cord-310847-63gh2tg4	862	26	binding	bind	VBG
cord-310847-63gh2tg4	862	27	effects	effect	NNS
cord-310847-63gh2tg4	862	28	on	on	IN
cord-310847-63gh2tg4	862	29	the	the	DT
cord-310847-63gh2tg4	862	30	pH	ph	NN
cord-310847-63gh2tg4	862	31	,	,	,
cord-310847-63gh2tg4	862	32	thermal	thermal	JJ
cord-310847-63gh2tg4	862	33	and	and	CC
cord-310847-63gh2tg4	862	34	urea	urea	NN
cord-310847-63gh2tg4	862	35	denaturation	denaturation	NN
cord-310847-63gh2tg4	862	36	transitions	transition	NNS
cord-310847-63gh2tg4	862	37	in	in	IN
cord-310847-63gh2tg4	862	38	alpha	alpha	NN
cord-310847-63gh2tg4	862	39	-	-	HYPH
cord-310847-63gh2tg4	862	40	lactalbumin	lactalbumin	JJ
cord-310847-63gh2tg4	863	1	The	the	DT
cord-310847-63gh2tg4	863	2	molten	molten	JJ
cord-310847-63gh2tg4	863	3	globule	globule	NN
cord-310847-63gh2tg4	863	4	state	state	NN
cord-310847-63gh2tg4	863	5	as	as	IN
cord-310847-63gh2tg4	863	6	a	a	DT
cord-310847-63gh2tg4	863	7	clue	clue	NN
cord-310847-63gh2tg4	863	8	for	for	IN
cord-310847-63gh2tg4	863	9	understanding	understand	VBG
cord-310847-63gh2tg4	863	10	the	the	DT
cord-310847-63gh2tg4	863	11	folding	folding	NN
cord-310847-63gh2tg4	863	12	and	and	CC
cord-310847-63gh2tg4	863	13	cooperativity	cooperativity	NN
cord-310847-63gh2tg4	863	14	of	of	IN
cord-310847-63gh2tg4	863	15	globular	globular	JJ
cord-310847-63gh2tg4	863	16	-	-	HYPH
cord-310847-63gh2tg4	863	17	protein	protein	NN
cord-310847-63gh2tg4	863	18	structure	structure	NN
cord-310847-63gh2tg4	863	19	alpha	alpha	NN
cord-310847-63gh2tg4	863	20	-	-	HYPH
cord-310847-63gh2tg4	863	21	Lactalbumin	lactalbumin	JJ
cord-310847-63gh2tg4	863	22	:	:	:
cord-310847-63gh2tg4	863	23	structure	structure	NN
cord-310847-63gh2tg4	863	24	and	and	CC
cord-310847-63gh2tg4	863	25	function	function	VB
cord-310847-63gh2tg4	863	26	How	how	WRB
cord-310847-63gh2tg4	863	27	to	to	TO
cord-310847-63gh2tg4	863	28	improve	improve	VB
cord-310847-63gh2tg4	863	29	nature	nature	NN
cord-310847-63gh2tg4	863	30	:	:	:
cord-310847-63gh2tg4	863	31	study	study	NN
cord-310847-63gh2tg4	863	32	of	of	IN
cord-310847-63gh2tg4	863	33	the	the	DT
cord-310847-63gh2tg4	863	34	electrostatic	electrostatic	JJ
cord-310847-63gh2tg4	863	35	properties	property	NNS
cord-310847-63gh2tg4	863	36	of	of	IN
cord-310847-63gh2tg4	863	37	the	the	DT
cord-310847-63gh2tg4	863	38	surface	surface	NN
cord-310847-63gh2tg4	863	39	of	of	IN
cord-310847-63gh2tg4	863	40	alpha	alpha	NN
cord-310847-63gh2tg4	863	41	-	-	HYPH
cord-310847-63gh2tg4	863	42	lactalbumin	lactalbumin	JJ
cord-310847-63gh2tg4	864	1	The	the	DT
cord-310847-63gh2tg4	864	2	molecular	molecular	JJ
cord-310847-63gh2tg4	864	3	basis	basis	NN
cord-310847-63gh2tg4	864	4	of	of	IN
cord-310847-63gh2tg4	864	5	excitation	excitation	NN
cord-310847-63gh2tg4	864	6	and	and	CC
cord-310847-63gh2tg4	864	7	adaptation	adaptation	NN
cord-310847-63gh2tg4	864	8	during	during	IN
cord-310847-63gh2tg4	864	9	chemotactic	chemotactic	JJ
cord-310847-63gh2tg4	864	10	sensory	sensory	JJ
cord-310847-63gh2tg4	864	11	transduction	transduction	NN
cord-310847-63gh2tg4	864	12	in	in	IN
cord-310847-63gh2tg4	864	13	bacteria	bacteria	NNS
cord-310847-63gh2tg4	864	14	Adaptation	adaptation	NN
cord-310847-63gh2tg4	864	15	and	and	CC
cord-310847-63gh2tg4	864	16	control	control	NN
cord-310847-63gh2tg4	864	17	circuits	circuit	NNS
cord-310847-63gh2tg4	864	18	in	in	IN
cord-310847-63gh2tg4	864	19	bacterial	bacterial	JJ
cord-310847-63gh2tg4	864	20	chemotaxis	chemotaxis	NN
cord-310847-63gh2tg4	864	21	Nonenzymatic	nonenzymatic	JJ
cord-310847-63gh2tg4	864	22	deamidation	deamidation	NN
cord-310847-63gh2tg4	864	23	of	of	IN
cord-310847-63gh2tg4	864	24	asparaginyl	asparaginyl	NNP
cord-310847-63gh2tg4	864	25	and	and	CC
cord-310847-63gh2tg4	864	26	glutaminyl	glutaminyl	NNP
cord-310847-63gh2tg4	864	27	residues	residue	NNS
cord-310847-63gh2tg4	864	28	in	in	IN
cord-310847-63gh2tg4	864	29	proteins	protein	NNS
cord-310847-63gh2tg4	864	30	Structure	Structure	NNP
cord-310847-63gh2tg4	864	31	of	of	IN
cord-310847-63gh2tg4	864	32	thermal	thermal	JJ
cord-310847-63gh2tg4	864	33	polymers	polymer	NNS
cord-310847-63gh2tg4	864	34	of	of	IN
cord-310847-63gh2tg4	864	35	amino	amino	NN
cord-310847-63gh2tg4	864	36	acids	acid	NNS
cord-310847-63gh2tg4	864	37	Vitamin	vitamin	NN
cord-310847-63gh2tg4	864	38	K	k	NN
cord-310847-63gh2tg4	864	39	-	-	HYPH
cord-310847-63gh2tg4	864	40	dependent	dependent	JJ
cord-310847-63gh2tg4	864	41	gamma	gamma	NN
cord-310847-63gh2tg4	864	42	-	-	HYPH
cord-310847-63gh2tg4	864	43	glutamylcarboxylation	glutamylcarboxylation	NN
cord-310847-63gh2tg4	864	44	:	:	:
cord-310847-63gh2tg4	865	1	an	an	DT
cord-310847-63gh2tg4	865	2	ancient	ancient	JJ
cord-310847-63gh2tg4	865	3	posttranslational	posttranslational	JJ
cord-310847-63gh2tg4	865	4	modification	modification	NN
cord-310847-63gh2tg4	865	5	Polyglutamylation	Polyglutamylation	NNP
cord-310847-63gh2tg4	865	6	:	:	:
cord-310847-63gh2tg4	865	7	a	a	DT
cord-310847-63gh2tg4	865	8	fine	fine	JJ
cord-310847-63gh2tg4	865	9	-	-	HYPH
cord-310847-63gh2tg4	865	10	regulator	regulator	NN
cord-310847-63gh2tg4	865	11	of	of	IN
cord-310847-63gh2tg4	865	12	protein	protein	NN
cord-310847-63gh2tg4	865	13	function	function	NN
cord-310847-63gh2tg4	865	14	?	?	.
cord-310847-63gh2tg4	865	15	'	'	''
cord-310847-63gh2tg4	866	1	Protein	protein	NN
cord-310847-63gh2tg4	866	2	Modifications	modification	NNS
cord-310847-63gh2tg4	866	3	:	:	:
cord-310847-63gh2tg4	866	4	beyond	beyond	IN
cord-310847-63gh2tg4	866	5	the	the	DT
cord-310847-63gh2tg4	866	6	usual	usual	JJ
cord-310847-63gh2tg4	866	7	suspects	suspect	NNS
cord-310847-63gh2tg4	866	8	'	'	POS
cord-310847-63gh2tg4	866	9	review	review	NN
cord-310847-63gh2tg4	866	10	series	series	NN
cord-310847-63gh2tg4	866	11	Amino	Amino	NNP
cord-310847-63gh2tg4	866	12	acid	acid	NN
cord-310847-63gh2tg4	866	13	composition	composition	NN
cord-310847-63gh2tg4	866	14	of	of	IN
cord-310847-63gh2tg4	866	15	genomes	genome	NNS
cord-310847-63gh2tg4	866	16	,	,	,
cord-310847-63gh2tg4	866	17	lifestyles	lifestyle	NNS
cord-310847-63gh2tg4	866	18	of	of	IN
cord-310847-63gh2tg4	866	19	organisms	organism	NNS
cord-310847-63gh2tg4	866	20	,	,	,
cord-310847-63gh2tg4	866	21	and	and	CC
cord-310847-63gh2tg4	866	22	evolutionary	evolutionary	JJ
cord-310847-63gh2tg4	866	23	trends	trend	NNS
cord-310847-63gh2tg4	866	24	:	:	:
cord-310847-63gh2tg4	867	1	a	a	DT
cord-310847-63gh2tg4	867	2	global	global	JJ
cord-310847-63gh2tg4	867	3	picture	picture	NN
cord-310847-63gh2tg4	867	4	with	with	IN
cord-310847-63gh2tg4	867	5	correspondence	correspondence	NN
cord-310847-63gh2tg4	867	6	analysis	analysis	NN
cord-310847-63gh2tg4	867	7	Natively	natively	RB
cord-310847-63gh2tg4	867	8	unfolded	unfold	VBD
cord-310847-63gh2tg4	868	1	human	human	JJ
cord-310847-63gh2tg4	868	2	prothymosin	prothymosin	NNP
cord-310847-63gh2tg4	868	3	alpha	alpha	NNP
cord-310847-63gh2tg4	868	4	adopts	adopt	VBZ
cord-310847-63gh2tg4	868	5	partially	partially	RB
cord-310847-63gh2tg4	868	6	folded	fold	VBN
cord-310847-63gh2tg4	868	7	collapsed	collapsed	JJ
cord-310847-63gh2tg4	868	8	conformation	conformation	NN
cord-310847-63gh2tg4	868	9	at	at	IN
cord-310847-63gh2tg4	868	10	acidic	acidic	JJ
cord-310847-63gh2tg4	868	11	pH	pH	NNP
cord-310847-63gh2tg4	868	12	Prothymosin	Prothymosin	NNP
cord-310847-63gh2tg4	868	13	alpha	alpha	NN
cord-310847-63gh2tg4	868	14	:	:	:
cord-310847-63gh2tg4	868	15	a	a	DT
cord-310847-63gh2tg4	868	16	biologically	biologically	RB
cord-310847-63gh2tg4	868	17	active	active	JJ
cord-310847-63gh2tg4	868	18	protein	protein	NN
cord-310847-63gh2tg4	868	19	with	with	IN
cord-310847-63gh2tg4	868	20	random	random	JJ
cord-310847-63gh2tg4	868	21	coil	coil	NN
cord-310847-63gh2tg4	868	22	conformation	conformation	NN
cord-310847-63gh2tg4	868	23	Poly	Poly	NNP
cord-310847-63gh2tg4	868	24	-	-	HYPH
cord-310847-63gh2tg4	868	25	gamma	gamma	NN
cord-310847-63gh2tg4	868	26	-	-	HYPH
cord-310847-63gh2tg4	868	27	glutamate	glutamate	NN
cord-310847-63gh2tg4	868	28	in	in	IN
cord-310847-63gh2tg4	868	29	bacteria	bacteria	NNS
cord-310847-63gh2tg4	868	30	Conformational	Conformational	NNP
cord-310847-63gh2tg4	868	31	Studies	Studies	NNPS
cord-310847-63gh2tg4	868	32	on	on	IN
cord-310847-63gh2tg4	868	33	Synthetic	Synthetic	NNP
cord-310847-63gh2tg4	868	34	Poly	Poly	NNP
cord-310847-63gh2tg4	868	35	-	-	HYPH
cord-310847-63gh2tg4	868	36	Alpha	Alpha	NNP
cord-310847-63gh2tg4	868	37	-	-	HYPH
cord-310847-63gh2tg4	868	38	Amino	Amino	NNP
cord-310847-63gh2tg4	868	39	Acids	acid	NNS
cord-310847-63gh2tg4	868	40	:	:	:
cord-310847-63gh2tg4	868	41	Factors	factor	NNS
cord-310847-63gh2tg4	868	42	Influencing	influence	VBG
cord-310847-63gh2tg4	868	43	the	the	DT
cord-310847-63gh2tg4	868	44	Stability	stability	NN
cord-310847-63gh2tg4	868	45	of	of	IN
cord-310847-63gh2tg4	868	46	the	the	DT
cord-310847-63gh2tg4	868	47	Helical	Helical	NNP
cord-310847-63gh2tg4	868	48	Conformation	Conformation	NNP
cord-310847-63gh2tg4	868	49	of	of	IN
cord-310847-63gh2tg4	868	50	Poly	Poly	NNP
cord-310847-63gh2tg4	868	51	-	-	HYPH
cord-310847-63gh2tg4	868	52	L	L	NNP
cord-310847-63gh2tg4	868	53	-	-	HYPH
cord-310847-63gh2tg4	868	54	Glutamic	Glutamic	NNP
cord-310847-63gh2tg4	868	55	Acid	Acid	NNP
cord-310847-63gh2tg4	868	56	and	and	CC
cord-310847-63gh2tg4	868	57	Copolymers	Copolymers	NNPS
cord-310847-63gh2tg4	868	58	of	of	IN
cord-310847-63gh2tg4	868	59	L	L	NNP
cord-310847-63gh2tg4	868	60	-	-	HYPH
cord-310847-63gh2tg4	868	61	Glutamic	Glutamic	NNP
cord-310847-63gh2tg4	868	62	Acid	Acid	NNP
cord-310847-63gh2tg4	868	63	and	and	CC
cord-310847-63gh2tg4	868	64	L	l	NN
cord-310847-63gh2tg4	868	65	-	-	HYPH
cord-310847-63gh2tg4	868	66	Leucine	Leucine	NNP
cord-310847-63gh2tg4	868	67	Human	human	JJ
cord-310847-63gh2tg4	868	68	matrix	matrix	NN
cord-310847-63gh2tg4	868	69	metalloproteinases	metalloproteinase	NNS
cord-310847-63gh2tg4	868	70	:	:	:
cord-310847-63gh2tg4	868	71	an	an	DT
cord-310847-63gh2tg4	868	72	ubiquitarian	ubiquitarian	JJ
cord-310847-63gh2tg4	868	73	class	class	NN
cord-310847-63gh2tg4	868	74	of	of	IN
cord-310847-63gh2tg4	868	75	enzymes	enzyme	NNS
cord-310847-63gh2tg4	868	76	involved	involve	VBN
cord-310847-63gh2tg4	868	77	in	in	IN
cord-310847-63gh2tg4	868	78	several	several	JJ
cord-310847-63gh2tg4	868	79	pathological	pathological	JJ
cord-310847-63gh2tg4	868	80	processes	process	NNS
cord-310847-63gh2tg4	869	1	The	the	DT
cord-310847-63gh2tg4	869	2	LZT	LZT	NNP
cord-310847-63gh2tg4	869	3	proteins	protein	NNS
cord-310847-63gh2tg4	869	4	;	;	:
cord-310847-63gh2tg4	869	5	the	the	DT
cord-310847-63gh2tg4	869	6	LIV-1	LIV-1	NNP
cord-310847-63gh2tg4	869	7	subfamily	subfamily	NN
cord-310847-63gh2tg4	869	8	of	of	IN
cord-310847-63gh2tg4	869	9	zinc	zinc	NN
cord-310847-63gh2tg4	869	10	transporters	transporter	NNS
cord-310847-63gh2tg4	869	11	Plant	Plant	NNP
cord-310847-63gh2tg4	869	12	lysozymes	lysozyme	VBZ
cord-310847-63gh2tg4	869	13	Relationship	relationship	NN
cord-310847-63gh2tg4	869	14	of	of	IN
cord-310847-63gh2tg4	869	15	sequence	sequence	NN
cord-310847-63gh2tg4	869	16	and	and	CC
cord-310847-63gh2tg4	869	17	structure	structure	NN
cord-310847-63gh2tg4	869	18	to	to	IN
cord-310847-63gh2tg4	869	19	specificity	specificity	NN
cord-310847-63gh2tg4	869	20	in	in	IN
cord-310847-63gh2tg4	869	21	the	the	DT
cord-310847-63gh2tg4	869	22	alphaamylase	alphaamylase	NN
cord-310847-63gh2tg4	869	23	family	family	NN
cord-310847-63gh2tg4	869	24	of	of	IN
cord-310847-63gh2tg4	869	25	enzymes	enzyme	NNS
cord-310847-63gh2tg4	870	1	Conserved	conserved	JJ
cord-310847-63gh2tg4	870	2	structural	structural	JJ
cord-310847-63gh2tg4	870	3	motifs	motif	NNS
cord-310847-63gh2tg4	870	4	governing	govern	VBG
cord-310847-63gh2tg4	870	5	the	the	DT
cord-310847-63gh2tg4	870	6	stoichiometric	stoichiometric	JJ
cord-310847-63gh2tg4	870	7	repair	repair	NN
cord-310847-63gh2tg4	870	8	of	of	IN
cord-310847-63gh2tg4	870	9	alkylated	alkylated	JJ
cord-310847-63gh2tg4	870	10	DNA	dna	NN
cord-310847-63gh2tg4	870	11	by	by	IN
cord-310847-63gh2tg4	870	12	O(6)-alkylguanine	o(6)-alkylguanine	JJ
cord-310847-63gh2tg4	870	13	-	-	HYPH
cord-310847-63gh2tg4	870	14	DNA	dna	NN
cord-310847-63gh2tg4	870	15	alkyltransferase	alkyltransferase	NN
cord-310847-63gh2tg4	870	16	Three	Three	NNP
cord-310847-63gh2tg4	870	17	-	-	HYPH
cord-310847-63gh2tg4	870	18	dimensional	dimensional	JJ
cord-310847-63gh2tg4	870	19	structure	structure	NN
cord-310847-63gh2tg4	870	20	and	and	CC
cord-310847-63gh2tg4	870	21	molecular	molecular	JJ
cord-310847-63gh2tg4	870	22	mechanism	mechanism	NN
cord-310847-63gh2tg4	870	23	of	of	IN
cord-310847-63gh2tg4	870	24	novel	novel	JJ
cord-310847-63gh2tg4	870	25	enzymes	enzyme	NNS
cord-310847-63gh2tg4	870	26	of	of	IN
cord-310847-63gh2tg4	870	27	spore	spore	NN
cord-310847-63gh2tg4	870	28	-	-	HYPH
cord-310847-63gh2tg4	870	29	forming	form	VBG
cord-310847-63gh2tg4	870	30	bacteria	bacteria	NNS
cord-310847-63gh2tg4	870	31	Crystallographic	crystallographic	JJ
cord-310847-63gh2tg4	870	32	evidence	evidence	NN
cord-310847-63gh2tg4	870	33	for	for	IN
cord-310847-63gh2tg4	870	34	active	active	JJ
cord-310847-63gh2tg4	870	35	-	-	HYPH
cord-310847-63gh2tg4	870	36	site	site	NN
cord-310847-63gh2tg4	870	37	dynamics	dynamic	NNS
cord-310847-63gh2tg4	870	38	in	in	IN
cord-310847-63gh2tg4	870	39	the	the	DT
cord-310847-63gh2tg4	870	40	hydrolytic	hydrolytic	JJ
cord-310847-63gh2tg4	870	41	aldehyde	aldehyde	NN
cord-310847-63gh2tg4	870	42	dehydrogenases	dehydrogenase	NNS
cord-310847-63gh2tg4	870	43	.	.	.
cord-310847-63gh2tg4	871	1	Implications	implication	NNS
cord-310847-63gh2tg4	871	2	for	for	IN
cord-310847-63gh2tg4	871	3	the	the	DT
cord-310847-63gh2tg4	871	4	deacylation	deacylation	NN
cord-310847-63gh2tg4	871	5	step	step	NN
cord-310847-63gh2tg4	871	6	of	of	IN
cord-310847-63gh2tg4	871	7	the	the	DT
cord-310847-63gh2tg4	871	8	catalyzed	catalyzed	JJ
cord-310847-63gh2tg4	871	9	reaction	reaction	NN
cord-310847-63gh2tg4	871	10	Structures	structure	NNS
cord-310847-63gh2tg4	871	11	and	and	CC
cord-310847-63gh2tg4	871	12	mechanisms	mechanism	NNS
cord-310847-63gh2tg4	871	13	of	of	IN
cord-310847-63gh2tg4	871	14	Nudix	Nudix	NNP
cord-310847-63gh2tg4	871	15	hydrolases	hydrolase	NNS
cord-310847-63gh2tg4	872	1	An	an	DT
cord-310847-63gh2tg4	872	2	alternative	alternative	JJ
cord-310847-63gh2tg4	872	3	view	view	NN
cord-310847-63gh2tg4	872	4	of	of	IN
cord-310847-63gh2tg4	872	5	the	the	DT
cord-310847-63gh2tg4	872	6	proposed	propose	VBN
cord-310847-63gh2tg4	872	7	alternative	alternative	JJ
cord-310847-63gh2tg4	872	8	activities	activity	NNS
cord-310847-63gh2tg4	872	9	of	of	IN
cord-310847-63gh2tg4	872	10	hemopexin	hemopexin	JJ
cord-310847-63gh2tg4	872	11	High	high	JJ
cord-310847-63gh2tg4	872	12	-	-	HYPH
cord-310847-63gh2tg4	872	13	resolution	resolution	NN
cord-310847-63gh2tg4	872	14	structural	structural	JJ
cord-310847-63gh2tg4	872	15	studies	study	NNS
cord-310847-63gh2tg4	872	16	of	of	IN
cord-310847-63gh2tg4	872	17	the	the	DT
cord-310847-63gh2tg4	872	18	retinal	retinal	JJ
cord-310847-63gh2tg4	872	19	--	--	:
cord-310847-63gh2tg4	872	20	Glu113	glu113	ADD
cord-310847-63gh2tg4	872	21	interaction	interaction	NN
cord-310847-63gh2tg4	872	22	in	in	IN
cord-310847-63gh2tg4	872	23	rhodopsin	rhodopsin	NN
cord-310847-63gh2tg4	872	24	GluVII:06	gluvii:06	NN
cord-310847-63gh2tg4	872	25	-	-	HYPH
cord-310847-63gh2tg4	872	26	-a	-a	:
cord-310847-63gh2tg4	872	27	highly	highly	RB
cord-310847-63gh2tg4	872	28	conserved	conserved	JJ
cord-310847-63gh2tg4	872	29	and	and	CC
cord-310847-63gh2tg4	872	30	selective	selective	JJ
cord-310847-63gh2tg4	872	31	anchor	anchor	NN
cord-310847-63gh2tg4	872	32	point	point	NN
cord-310847-63gh2tg4	872	33	for	for	IN
cord-310847-63gh2tg4	872	34	non	non	JJ
cord-310847-63gh2tg4	872	35	-	-	JJ
cord-310847-63gh2tg4	872	36	peptide	peptide	JJ
cord-310847-63gh2tg4	872	37	ligands	ligand	NNS
cord-310847-63gh2tg4	872	38	in	in	IN
cord-310847-63gh2tg4	872	39	chemokine	chemokine	NN
cord-310847-63gh2tg4	872	40	receptors	receptor	NNS
cord-310847-63gh2tg4	872	41	Integrin	Integrin	NNP
cord-310847-63gh2tg4	872	42	-	-	HYPH
cord-310847-63gh2tg4	872	43	collagen	collagen	NN
cord-310847-63gh2tg4	872	44	complex	complex	NN
cord-310847-63gh2tg4	872	45	:	:	:
cord-310847-63gh2tg4	872	46	a	a	DT
cord-310847-63gh2tg4	872	47	metal	metal	NN
cord-310847-63gh2tg4	872	48	-	-	HYPH
cord-310847-63gh2tg4	872	49	glutamate	glutamate	NN
cord-310847-63gh2tg4	872	50	handshake	handshake	NN
cord-310847-63gh2tg4	873	1	The	the	DT
cord-310847-63gh2tg4	873	2	structure	structure	NN
cord-310847-63gh2tg4	873	3	of	of	IN
cord-310847-63gh2tg4	873	4	the	the	DT
cord-310847-63gh2tg4	873	5	two	two	CD
cord-310847-63gh2tg4	873	6	amino	amino	NN
cord-310847-63gh2tg4	873	7	-	-	HYPH
cord-310847-63gh2tg4	873	8	terminal	terminal	NN
cord-310847-63gh2tg4	873	9	domains	domain	NNS
cord-310847-63gh2tg4	873	10	of	of	IN
cord-310847-63gh2tg4	873	11	human	human	JJ
cord-310847-63gh2tg4	873	12	ICAM-1	icam-1	NN
cord-310847-63gh2tg4	873	13	suggests	suggest	VBZ
cord-310847-63gh2tg4	873	14	how	how	WRB
cord-310847-63gh2tg4	873	15	it	-PRON-	PRP
cord-310847-63gh2tg4	873	16	functions	function	VBZ
cord-310847-63gh2tg4	873	17	as	as	IN
cord-310847-63gh2tg4	873	18	a	a	DT
cord-310847-63gh2tg4	873	19	rhinovirus	rhinovirus	NN
cord-310847-63gh2tg4	873	20	receptor	receptor	NN
cord-310847-63gh2tg4	873	21	and	and	CC
cord-310847-63gh2tg4	873	22	as	as	IN
cord-310847-63gh2tg4	873	23	an	an	DT
cord-310847-63gh2tg4	873	24	LFA-1	LFA-1	NNP
cord-310847-63gh2tg4	873	25	integrin	integrin	NN
cord-310847-63gh2tg4	873	26	ligand	ligand	NN
cord-310847-63gh2tg4	873	27	Structural	structural	JJ
cord-310847-63gh2tg4	873	28	basis	basis	NN
cord-310847-63gh2tg4	873	29	of	of	IN
cord-310847-63gh2tg4	873	30	collagen	collagen	NN
cord-310847-63gh2tg4	873	31	recognition	recognition	NN
cord-310847-63gh2tg4	873	32	by	by	IN
cord-310847-63gh2tg4	873	33	integrin	integrin	NN
cord-310847-63gh2tg4	873	34	alpha2beta1	alpha2beta1	NNP
cord-310847-63gh2tg4	873	35	Coming	come	VBG
cord-310847-63gh2tg4	873	36	to	to	IN
cord-310847-63gh2tg4	873	37	grips	grip	NNS
cord-310847-63gh2tg4	873	38	with	with	IN
cord-310847-63gh2tg4	873	39	integrin	integrin	NN
cord-310847-63gh2tg4	873	40	binding	bind	VBG
cord-310847-63gh2tg4	873	41	to	to	IN
cord-310847-63gh2tg4	873	42	ligands	ligand	NNS
cord-310847-63gh2tg4	874	1	The	the	DT
cord-310847-63gh2tg4	874	2	biochemical	biochemical	JJ
cord-310847-63gh2tg4	874	3	basis	basis	NN
cord-310847-63gh2tg4	874	4	of	of	IN
cord-310847-63gh2tg4	874	5	zinc	zinc	NN
cord-310847-63gh2tg4	874	6	physiology	physiology	NN
cord-310847-63gh2tg4	874	7	Calcium	calcium	NN
cord-310847-63gh2tg4	874	8	binding	binding	NN
cord-310847-63gh2tg4	874	9	proteins	protein	NNS
cord-310847-63gh2tg4	874	10	Molecular	molecular	JJ
cord-310847-63gh2tg4	874	11	elements	element	NNS
cord-310847-63gh2tg4	874	12	of	of	IN
cord-310847-63gh2tg4	874	13	ion	ion	NN
cord-310847-63gh2tg4	874	14	permeation	permeation	NN
cord-310847-63gh2tg4	874	15	and	and	CC
cord-310847-63gh2tg4	874	16	selectivity	selectivity	NN
cord-310847-63gh2tg4	874	17	within	within	IN
cord-310847-63gh2tg4	874	18	calcium	calcium	NN
cord-310847-63gh2tg4	874	19	channels	channel	NNS
cord-310847-63gh2tg4	875	1	Diverse	diverse	JJ
cord-310847-63gh2tg4	875	2	gating	gate	VBG
cord-310847-63gh2tg4	875	3	in	in	IN
cord-310847-63gh2tg4	875	4	K+	K+	NNP
cord-310847-63gh2tg4	875	5	channels	channel	NNS
cord-310847-63gh2tg4	875	6	:	:	:
cord-310847-63gh2tg4	875	7	differential	differential	JJ
cord-310847-63gh2tg4	875	8	role	role	NN
cord-310847-63gh2tg4	875	9	of	of	IN
cord-310847-63gh2tg4	875	10	the	the	DT
cord-310847-63gh2tg4	875	11	pore	pore	NN
cord-310847-63gh2tg4	875	12	-	-	HYPH
cord-310847-63gh2tg4	875	13	helix	helix	NN
cord-310847-63gh2tg4	875	14	glutamate	glutamate	NN
cord-310847-63gh2tg4	875	15	in	in	IN
cord-310847-63gh2tg4	875	16	stabilizing	stabilize	VBG
cord-310847-63gh2tg4	875	17	the	the	DT
cord-310847-63gh2tg4	875	18	channel	channel	NN
cord-310847-63gh2tg4	875	19	pore	pore	NN
cord-310847-63gh2tg4	875	20	Basigin	Basigin	NNP
cord-310847-63gh2tg4	875	21	(	(	-LRB-
cord-310847-63gh2tg4	875	22	CD147	CD147	NNP
cord-310847-63gh2tg4	875	23	)	)	-RRB-
cord-310847-63gh2tg4	875	24	:	:	:
cord-310847-63gh2tg4	875	25	a	a	DT
cord-310847-63gh2tg4	875	26	multifunctional	multifunctional	JJ
cord-310847-63gh2tg4	875	27	transmembrane	transmembrane	NN
cord-310847-63gh2tg4	875	28	protein	protein	NN
cord-310847-63gh2tg4	875	29	involved	involve	VBN
cord-310847-63gh2tg4	875	30	in	in	IN
cord-310847-63gh2tg4	875	31	reproduction	reproduction	NN
cord-310847-63gh2tg4	875	32	,	,	,
cord-310847-63gh2tg4	875	33	neural	neural	JJ
cord-310847-63gh2tg4	875	34	function	function	NN
cord-310847-63gh2tg4	875	35	,	,	,
cord-310847-63gh2tg4	875	36	inflammation	inflammation	NN
cord-310847-63gh2tg4	875	37	and	and	CC
cord-310847-63gh2tg4	875	38	tumor	tumor	NN
cord-310847-63gh2tg4	875	39	invasion	invasion	NN
cord-310847-63gh2tg4	875	40	Unique	unique	JJ
cord-310847-63gh2tg4	875	41	structure	structure	NN
cord-310847-63gh2tg4	875	42	and	and	CC
cord-310847-63gh2tg4	875	43	function	function	NN
cord-310847-63gh2tg4	875	44	of	of	IN
cord-310847-63gh2tg4	875	45	chloride	chloride	NN
cord-310847-63gh2tg4	875	46	transporting	transport	VBG
cord-310847-63gh2tg4	875	47	CLC	CLC	NNP
cord-310847-63gh2tg4	875	48	proteins	protein	NNS
cord-310847-63gh2tg4	875	49	Physiological	physiological	JJ
cord-310847-63gh2tg4	875	50	functions	function	NNS
cord-310847-63gh2tg4	875	51	of	of	IN
cord-310847-63gh2tg4	875	52	CLC	CLC	NNP
cord-310847-63gh2tg4	875	53	Cl	Cl	NNP
cord-310847-63gh2tg4	875	54	−	−	CD
cord-310847-63gh2tg4	875	55	channels	channel	NNS
cord-310847-63gh2tg4	875	56	gleaned	glean	VBN
cord-310847-63gh2tg4	875	57	from	from	IN
cord-310847-63gh2tg4	875	58	human	human	JJ
cord-310847-63gh2tg4	875	59	genetic	genetic	JJ
cord-310847-63gh2tg4	875	60	disease	disease	NN
cord-310847-63gh2tg4	875	61	and	and	CC
cord-310847-63gh2tg4	875	62	mouse	mouse	NN
cord-310847-63gh2tg4	875	63	models	model	NNS
cord-310847-63gh2tg4	875	64	Proton	proton	NN
cord-310847-63gh2tg4	875	65	pump	pump	NN
cord-310847-63gh2tg4	875	66	coupled	couple	VBN
cord-310847-63gh2tg4	875	67	to	to	IN
cord-310847-63gh2tg4	875	68	cytochrome	cytochrome	NN
cord-310847-63gh2tg4	875	69	c	c	NN
cord-310847-63gh2tg4	875	70	oxidase	oxidase	NN
cord-310847-63gh2tg4	875	71	in	in	IN
cord-310847-63gh2tg4	875	72	mitochondria	mitochondrion	NNS
cord-310847-63gh2tg4	875	73	Oxygen	Oxygen	NNP
cord-310847-63gh2tg4	875	74	activation	activation	NN
cord-310847-63gh2tg4	875	75	and	and	CC
cord-310847-63gh2tg4	875	76	the	the	DT
cord-310847-63gh2tg4	875	77	conservation	conservation	NN
cord-310847-63gh2tg4	875	78	of	of	IN
cord-310847-63gh2tg4	875	79	energy	energy	NN
cord-310847-63gh2tg4	875	80	in	in	IN
cord-310847-63gh2tg4	875	81	cell	cell	NN
cord-310847-63gh2tg4	875	82	respiration	respiration	NN
cord-310847-63gh2tg4	875	83	Cytochrome	cytochrome	NN
cord-310847-63gh2tg4	875	84	c	c	NN
cord-310847-63gh2tg4	875	85	oxidase	oxidase	NN
cord-310847-63gh2tg4	875	86	:	:	:
cord-310847-63gh2tg4	875	87	exciting	exciting	JJ
cord-310847-63gh2tg4	875	88	progress	progress	NN
cord-310847-63gh2tg4	875	89	and	and	CC
cord-310847-63gh2tg4	875	90	remaining	remain	VBG
cord-310847-63gh2tg4	875	91	mysteries	mystery	NNS
cord-310847-63gh2tg4	875	92	Proton	proton	NN
cord-310847-63gh2tg4	875	93	-	-	HYPH
cord-310847-63gh2tg4	875	94	pumping	pump	VBG
cord-310847-63gh2tg4	875	95	mechanism	mechanism	NN
cord-310847-63gh2tg4	875	96	of	of	IN
cord-310847-63gh2tg4	875	97	cytochrome	cytochrome	NN
cord-310847-63gh2tg4	875	98	c	c	NN
cord-310847-63gh2tg4	875	99	oxidase	oxidase	NN
cord-310847-63gh2tg4	875	100	:	:	:
cord-310847-63gh2tg4	875	101	a	a	DT
cord-310847-63gh2tg4	875	102	kinetic	kinetic	JJ
cord-310847-63gh2tg4	875	103	master	master	NN
cord-310847-63gh2tg4	875	104	-	-	HYPH
cord-310847-63gh2tg4	875	105	equation	equation	NN
cord-310847-63gh2tg4	875	106	approach	approach	NN
cord-310847-63gh2tg4	875	107	Coupling	Coupling	NNP
cord-310847-63gh2tg4	875	108	of	of	IN
cord-310847-63gh2tg4	875	109	phosphorylation	phosphorylation	NN
cord-310847-63gh2tg4	875	110	to	to	IN
cord-310847-63gh2tg4	875	111	electron	electron	NN
cord-310847-63gh2tg4	875	112	and	and	CC
cord-310847-63gh2tg4	875	113	hydrogen	hydrogen	NN
cord-310847-63gh2tg4	875	114	transfer	transfer	NN
cord-310847-63gh2tg4	875	115	by	by	IN
cord-310847-63gh2tg4	875	116	a	a	DT
cord-310847-63gh2tg4	875	117	chemi	chemi	JJ
cord-310847-63gh2tg4	875	118	-	-	JJ
cord-310847-63gh2tg4	875	119	osmotic	osmotic	JJ
cord-310847-63gh2tg4	875	120	type	type	NN
cord-310847-63gh2tg4	875	121	of	of	IN
cord-310847-63gh2tg4	875	122	mechanism	mechanism	NN
cord-310847-63gh2tg4	875	123	Glutamic	Glutamic	NNP
cord-310847-63gh2tg4	875	124	acid	acid	NN
cord-310847-63gh2tg4	875	125	242	242	CD
cord-310847-63gh2tg4	876	1	is	be	VBZ
cord-310847-63gh2tg4	876	2	a	a	DT
cord-310847-63gh2tg4	876	3	valve	valve	NN
cord-310847-63gh2tg4	876	4	in	in	IN
cord-310847-63gh2tg4	876	5	the	the	DT
cord-310847-63gh2tg4	876	6	proton	proton	NN
cord-310847-63gh2tg4	876	7	pump	pump	NN
cord-310847-63gh2tg4	876	8	of	of	IN
cord-310847-63gh2tg4	876	9	cytochrome	cytochrome	NN
cord-310847-63gh2tg4	876	10	c	c	NN
cord-310847-63gh2tg4	876	11	oxidase	oxidase	NN
cord-310847-63gh2tg4	876	12	Cell	Cell	NNP
cord-310847-63gh2tg4	876	13	biology	biology	NN
cord-310847-63gh2tg4	876	14	and	and	CC
cord-310847-63gh2tg4	876	15	molecular	molecular	JJ
cord-310847-63gh2tg4	876	16	basis	basis	NN
cord-310847-63gh2tg4	876	17	of	of	IN
cord-310847-63gh2tg4	876	18	denitrification	denitrification	NN
cord-310847-63gh2tg4	877	1	Inorganic	inorganic	JJ
cord-310847-63gh2tg4	877	2	nitrogen	nitrogen	NN
cord-310847-63gh2tg4	877	3	metabolism	metabolism	NN
cord-310847-63gh2tg4	877	4	in	in	IN
cord-310847-63gh2tg4	877	5	bacteria	bacteria	NNS
cord-310847-63gh2tg4	877	6	Molecular	molecular	JJ
cord-310847-63gh2tg4	877	7	structure	structure	NN
cord-310847-63gh2tg4	877	8	and	and	CC
cord-310847-63gh2tg4	877	9	function	function	NN
cord-310847-63gh2tg4	877	10	of	of	IN
cord-310847-63gh2tg4	877	11	bacterial	bacterial	JJ
cord-310847-63gh2tg4	877	12	nitric	nitric	NN
cord-310847-63gh2tg4	877	13	oxide	oxide	NN
cord-310847-63gh2tg4	877	14	reductase	reductase	NN
cord-310847-63gh2tg4	877	15	Mono	Mono	NNP
cord-310847-63gh2tg4	877	16	-	-	HYPH
cord-310847-63gh2tg4	877	17	ADP	adp	NN
cord-310847-63gh2tg4	877	18	-	-	HYPH
cord-310847-63gh2tg4	877	19	ribosylation	ribosylation	NN
cord-310847-63gh2tg4	877	20	:	:	:
cord-310847-63gh2tg4	877	21	a	a	DT
cord-310847-63gh2tg4	877	22	reversible	reversible	JJ
cord-310847-63gh2tg4	877	23	posttranslational	posttranslational	JJ
cord-310847-63gh2tg4	877	24	modification	modification	NN
cord-310847-63gh2tg4	877	25	of	of	IN
cord-310847-63gh2tg4	877	26	proteins	protein	NNS
cord-310847-63gh2tg4	877	27	Structure	structure	NN
cord-310847-63gh2tg4	877	28	-	-	HYPH
cord-310847-63gh2tg4	877	29	function	function	NN
cord-310847-63gh2tg4	877	30	relationships	relationship	NNS
cord-310847-63gh2tg4	877	31	of	of	IN
cord-310847-63gh2tg4	877	32	Na(+	Na(+	NNP
cord-310847-63gh2tg4	877	33	)	)	-RRB-
cord-310847-63gh2tg4	877	34	,	,	,
cord-310847-63gh2tg4	877	35	K(+	k(+	RB
cord-310847-63gh2tg4	877	36	)	)	-RRB-
cord-310847-63gh2tg4	877	37	,	,	,
cord-310847-63gh2tg4	877	38	ATP	ATP	NNP
cord-310847-63gh2tg4	877	39	,	,	,
cord-310847-63gh2tg4	877	40	or	or	CC
cord-310847-63gh2tg4	877	41	Mg(2	Mg(2	NNP
cord-310847-63gh2tg4	877	42	+	+	SYM
cord-310847-63gh2tg4	877	43	)	)	-RRB-
cord-310847-63gh2tg4	877	44	binding	binding	NN
cord-310847-63gh2tg4	877	45	and	and	CC
cord-310847-63gh2tg4	877	46	energy	energy	NN
cord-310847-63gh2tg4	877	47	transduction	transduction	NN
cord-310847-63gh2tg4	877	48	in	in	IN
cord-310847-63gh2tg4	877	49	Na	Na	NNP
cord-310847-63gh2tg4	877	50	,	,	,
cord-310847-63gh2tg4	877	51	K	K	NNP
cord-310847-63gh2tg4	877	52	-	-	HYPH
cord-310847-63gh2tg4	877	53	ATPase	ATPase	NNP
cord-310847-63gh2tg4	877	54	Narberhaus	Narberhaus	NNP
cord-310847-63gh2tg4	877	55	F.	F.	NNP
cord-310847-63gh2tg4	877	56	Alpha	alpha	NN
cord-310847-63gh2tg4	877	57	-	-	HYPH
cord-310847-63gh2tg4	877	58	crystallin	crystallin	JJ
cord-310847-63gh2tg4	877	59	-	-	HYPH
cord-310847-63gh2tg4	877	60	type	type	NN
cord-310847-63gh2tg4	877	61	heat	heat	NN
cord-310847-63gh2tg4	877	62	shock	shock	NN
cord-310847-63gh2tg4	877	63	proteins	protein	NNS
cord-310847-63gh2tg4	877	64	:	:	:
cord-310847-63gh2tg4	877	65	socializing	socialize	VBG
cord-310847-63gh2tg4	877	66	minichaperones	minichaperone	NNS
cord-310847-63gh2tg4	877	67	in	in	IN
cord-310847-63gh2tg4	877	68	the	the	DT
cord-310847-63gh2tg4	877	69	context	context	NN
cord-310847-63gh2tg4	877	70	of	of	IN
cord-310847-63gh2tg4	877	71	a	a	DT
cord-310847-63gh2tg4	877	72	multichaperone	multichaperone	NN
cord-310847-63gh2tg4	877	73	network	network	NN
cord-310847-63gh2tg4	877	74	Distinct	distinct	JJ
cord-310847-63gh2tg4	877	75	roles	role	NNS
cord-310847-63gh2tg4	877	76	of	of	IN
cord-310847-63gh2tg4	877	77	the	the	DT
cord-310847-63gh2tg4	877	78	N	n	CD
cord-310847-63gh2tg4	877	79	-	-	HYPH
cord-310847-63gh2tg4	877	80	terminal	terminal	NN
cord-310847-63gh2tg4	877	81	-	-	HYPH
cord-310847-63gh2tg4	877	82	binding	bind	VBG
cord-310847-63gh2tg4	877	83	domain	domain	NN
cord-310847-63gh2tg4	877	84	and	and	CC
cord-310847-63gh2tg4	877	85	the	the	DT
cord-310847-63gh2tg4	877	86	C	c	NN
cord-310847-63gh2tg4	877	87	-	-	HYPH
cord-310847-63gh2tg4	877	88	terminal	terminal	NN
cord-310847-63gh2tg4	877	89	-	-	HYPH
cord-310847-63gh2tg4	877	90	solubilizing	solubilize	VBG
cord-310847-63gh2tg4	877	91	domain	domain	NN
cord-310847-63gh2tg4	877	92	of	of	IN
cord-310847-63gh2tg4	877	93	alpha	alpha	NN
cord-310847-63gh2tg4	877	94	-	-	HYPH
cord-310847-63gh2tg4	877	95	synuclein	synuclein	NNP
cord-310847-63gh2tg4	877	96	,	,	,
cord-310847-63gh2tg4	877	97	a	a	DT
cord-310847-63gh2tg4	877	98	molecular	molecular	JJ
cord-310847-63gh2tg4	877	99	chaperone	chaperone	NN
cord-310847-63gh2tg4	877	100	Polyanions	Polyanions	NNP
cord-310847-63gh2tg4	877	101	and	and	CC
cord-310847-63gh2tg4	877	102	the	the	DT
cord-310847-63gh2tg4	877	103	proteome	proteome	NN
cord-310847-63gh2tg4	877	104	Physical	physical	JJ
cord-310847-63gh2tg4	877	105	stabilization	stabilization	NN
cord-310847-63gh2tg4	877	106	of	of	IN
cord-310847-63gh2tg4	877	107	acidic	acidic	JJ
cord-310847-63gh2tg4	877	108	fibroblast	fibroblast	NN
cord-310847-63gh2tg4	877	109	growth	growth	NN
cord-310847-63gh2tg4	877	110	factor	factor	NN
cord-310847-63gh2tg4	877	111	by	by	IN
cord-310847-63gh2tg4	877	112	polyanions	polyanion	NNS
cord-310847-63gh2tg4	877	113	Acceleration	Acceleration	NNP
cord-310847-63gh2tg4	877	114	of	of	IN
cord-310847-63gh2tg4	877	115	the	the	DT
cord-310847-63gh2tg4	877	116	refolding	refolding	NN
cord-310847-63gh2tg4	877	117	of	of	IN
cord-310847-63gh2tg4	877	118	Arc	Arc	NNP
cord-310847-63gh2tg4	877	119	repressor	repressor	NN
cord-310847-63gh2tg4	877	120	by	by	IN
cord-310847-63gh2tg4	877	121	nucleic	nucleic	JJ
cord-310847-63gh2tg4	877	122	acids	acid	NNS
cord-310847-63gh2tg4	877	123	and	and	CC
cord-310847-63gh2tg4	877	124	other	other	JJ
cord-310847-63gh2tg4	877	125	polyanions	polyanion	NNS
cord-310847-63gh2tg4	877	126	Complex	complex	JJ
cord-310847-63gh2tg4	877	127	effects	effect	NNS
cord-310847-63gh2tg4	877	128	of	of	IN
cord-310847-63gh2tg4	877	129	molecular	molecular	JJ
cord-310847-63gh2tg4	877	130	chaperones	chaperone	NNS
cord-310847-63gh2tg4	877	131	on	on	IN
cord-310847-63gh2tg4	877	132	the	the	DT
cord-310847-63gh2tg4	877	133	aggregation	aggregation	NN
cord-310847-63gh2tg4	877	134	and	and	CC
cord-310847-63gh2tg4	877	135	refolding	refolding	NN
cord-310847-63gh2tg4	877	136	of	of	IN
cord-310847-63gh2tg4	877	137	fibroblast	fibroblast	NN
cord-310847-63gh2tg4	877	138	growth	growth	NN
cord-310847-63gh2tg4	878	1	factor-1	factor-1	NNP
cord-310847-63gh2tg4	879	1	Mapping	map	VBG
cord-310847-63gh2tg4	879	2	the	the	DT
cord-310847-63gh2tg4	879	3	functional	functional	JJ
cord-310847-63gh2tg4	879	4	domains	domain	NNS
cord-310847-63gh2tg4	879	5	of	of	IN
cord-310847-63gh2tg4	879	6	nucleolar	nucleolar	JJ
cord-310847-63gh2tg4	879	7	protein	protein	NN
cord-310847-63gh2tg4	879	8	B23	B23	NNP
cord-310847-63gh2tg4	879	9	Chaperone	Chaperone	NNP
cord-310847-63gh2tg4	879	10	-	-	HYPH
cord-310847-63gh2tg4	879	11	like	like	JJ
cord-310847-63gh2tg4	879	12	activity	activity	NN
cord-310847-63gh2tg4	879	13	of	of	IN
cord-310847-63gh2tg4	879	14	tubulin	tubulin	NN
cord-310847-63gh2tg4	879	15	.	.	.
cord-310847-63gh2tg4	880	1	binding	binding	NN
cord-310847-63gh2tg4	880	2	and	and	CC
cord-310847-63gh2tg4	880	3	reactivation	reactivation	NN
cord-310847-63gh2tg4	880	4	of	of	IN
cord-310847-63gh2tg4	880	5	unfolded	unfold	VBN
cord-310847-63gh2tg4	880	6	substrate	substrate	NN
cord-310847-63gh2tg4	880	7	enzymes	enzyme	NNS
cord-310847-63gh2tg4	880	8	Role	role	NN
cord-310847-63gh2tg4	880	9	of	of	IN
cord-310847-63gh2tg4	880	10	the	the	DT
cord-310847-63gh2tg4	880	11	carboxy	carboxy	JJ
cord-310847-63gh2tg4	880	12	-	-	HYPH
cord-310847-63gh2tg4	880	13	termini	termini	NN
cord-310847-63gh2tg4	880	14	of	of	IN
cord-310847-63gh2tg4	880	15	tubulin	tubulin	NN
cord-310847-63gh2tg4	880	16	on	on	IN
cord-310847-63gh2tg4	880	17	its	-PRON-	PRP$
cord-310847-63gh2tg4	880	18	chaperone	chaperone	NN
cord-310847-63gh2tg4	880	19	-	-	HYPH
cord-310847-63gh2tg4	880	20	like	like	JJ
cord-310847-63gh2tg4	880	21	activity	activity	NN
cord-310847-63gh2tg4	880	22	Chaperone	chaperone	NN
cord-310847-63gh2tg4	880	23	-	-	HYPH
cord-310847-63gh2tg4	880	24	like	like	JJ
cord-310847-63gh2tg4	880	25	activity	activity	NN
cord-310847-63gh2tg4	880	26	of	of	IN
cord-310847-63gh2tg4	880	27	tubulin	tubulin	JJ
cord-310847-63gh2tg4	880	28	Productive	productive	JJ
cord-310847-63gh2tg4	880	29	folding	folding	NN
cord-310847-63gh2tg4	880	30	of	of	IN
cord-310847-63gh2tg4	880	31	human	human	JJ
cord-310847-63gh2tg4	880	32	neutrophil	neutrophil	NN
cord-310847-63gh2tg4	880	33	alpha	alpha	NN
cord-310847-63gh2tg4	880	34	-	-	HYPH
cord-310847-63gh2tg4	880	35	defensins	defensin	NNS
cord-310847-63gh2tg4	880	36	in	in	IN
cord-310847-63gh2tg4	880	37	vitro	vitro	FW
cord-310847-63gh2tg4	880	38	without	without	IN
cord-310847-63gh2tg4	880	39	the	the	DT
cord-310847-63gh2tg4	880	40	pro	pro	JJ
cord-310847-63gh2tg4	880	41	-	-	JJ
cord-310847-63gh2tg4	880	42	peptide	peptide	JJ
cord-310847-63gh2tg4	880	43	Pro	pro	JJ
cord-310847-63gh2tg4	880	44	-	-	NN
cord-310847-63gh2tg4	880	45	sequence	sequence	NN
cord-310847-63gh2tg4	880	46	of	of	IN
cord-310847-63gh2tg4	880	47	subtilisin	subtilisin	NNP
cord-310847-63gh2tg4	880	48	can	can	MD
cord-310847-63gh2tg4	880	49	guide	guide	VB
cord-310847-63gh2tg4	880	50	the	the	DT
cord-310847-63gh2tg4	880	51	refolding	refolding	NN
cord-310847-63gh2tg4	880	52	of	of	IN
cord-310847-63gh2tg4	880	53	denatured	denatured	JJ
cord-310847-63gh2tg4	880	54	subtilisin	subtilisin	NNS
cord-310847-63gh2tg4	880	55	in	in	IN
cord-310847-63gh2tg4	880	56	an	an	DT
cord-310847-63gh2tg4	880	57	intermolecular	intermolecular	JJ
cord-310847-63gh2tg4	880	58	process	process	NN
cord-310847-63gh2tg4	881	1	The	the	DT
cord-310847-63gh2tg4	881	2	alpha	alpha	NN
cord-310847-63gh2tg4	881	3	-	-	HYPH
cord-310847-63gh2tg4	881	4	lytic	lytic	JJ
cord-310847-63gh2tg4	881	5	protease	protease	NN
cord-310847-63gh2tg4	881	6	proregion	proregion	NN
cord-310847-63gh2tg4	881	7	does	do	VBZ
cord-310847-63gh2tg4	881	8	not	not	RB
cord-310847-63gh2tg4	881	9	require	require	VB
cord-310847-63gh2tg4	881	10	a	a	DT
cord-310847-63gh2tg4	881	11	physical	physical	JJ
cord-310847-63gh2tg4	881	12	linkage	linkage	NN
cord-310847-63gh2tg4	881	13	to	to	TO
cord-310847-63gh2tg4	881	14	activate	activate	VB
cord-310847-63gh2tg4	881	15	the	the	DT
cord-310847-63gh2tg4	881	16	protease	protease	NN
cord-310847-63gh2tg4	881	17	domain	domain	NN
cord-310847-63gh2tg4	881	18	in	in	IN
cord-310847-63gh2tg4	881	19	vivo	vivo	NNP
cord-310847-63gh2tg4	881	20	Analysis	Analysis	NNP
cord-310847-63gh2tg4	881	21	of	of	IN
cord-310847-63gh2tg4	881	22	prepro	prepro	JJ
cord-310847-63gh2tg4	881	23	-	-	HYPH
cord-310847-63gh2tg4	881	24	alpha	alpha	NN
cord-310847-63gh2tg4	881	25	-	-	HYPH
cord-310847-63gh2tg4	881	26	lytic	lytic	JJ
cord-310847-63gh2tg4	881	27	protease	protease	NN
cord-310847-63gh2tg4	881	28	expression	expression	NN
cord-310847-63gh2tg4	881	29	in	in	IN
cord-310847-63gh2tg4	881	30	Escherichia	Escherichia	NNP
cord-310847-63gh2tg4	881	31	coli	coli	NNS
cord-310847-63gh2tg4	881	32	reveals	reveal	VBZ
cord-310847-63gh2tg4	881	33	that	that	IN
cord-310847-63gh2tg4	881	34	the	the	DT
cord-310847-63gh2tg4	881	35	pro	pro	JJ
cord-310847-63gh2tg4	881	36	region	region	NN
cord-310847-63gh2tg4	881	37	is	be	VBZ
cord-310847-63gh2tg4	881	38	required	require	VBN
cord-310847-63gh2tg4	881	39	for	for	IN
cord-310847-63gh2tg4	881	40	activity	activity	NN
cord-310847-63gh2tg4	881	41	Heavy	Heavy	NNP
cord-310847-63gh2tg4	881	42	metal	metal	NN
cord-310847-63gh2tg4	881	43	detoxification	detoxification	NN
cord-310847-63gh2tg4	881	44	in	in	IN
cord-310847-63gh2tg4	881	45	higher	high	JJR
cord-310847-63gh2tg4	881	46	plants	plant	NNS
cord-310847-63gh2tg4	881	47	--	--	:
cord-310847-63gh2tg4	881	48	a	a	DT
cord-310847-63gh2tg4	881	49	review	review	NN
cord-310847-63gh2tg4	881	50	Modulation	modulation	NN
cord-310847-63gh2tg4	881	51	of	of	IN
cord-310847-63gh2tg4	881	52	mammalian	mammalian	JJ
cord-310847-63gh2tg4	881	53	sperm	sperm	NN
cord-310847-63gh2tg4	881	54	function	function	NN
cord-310847-63gh2tg4	881	55	by	by	IN
cord-310847-63gh2tg4	881	56	fertilization	fertilization	NN
cord-310847-63gh2tg4	881	57	promoting	promote	VBG
cord-310847-63gh2tg4	881	58	peptide	peptide	NN
cord-310847-63gh2tg4	881	59	(	(	-LRB-
cord-310847-63gh2tg4	881	60	FPP	FPP	NNP
cord-310847-63gh2tg4	881	61	)	)	-RRB-
cord-310847-63gh2tg4	881	62	Microbial	microbial	JJ
cord-310847-63gh2tg4	881	63	biosynthesis	biosynthesis	NN
cord-310847-63gh2tg4	881	64	of	of	IN
cord-310847-63gh2tg4	881	65	polyglutamic	polyglutamic	JJ
cord-310847-63gh2tg4	881	66	acid	acid	NNP
cord-310847-63gh2tg4	881	67	biopolymer	biopolymer	NNP
cord-310847-63gh2tg4	881	68	and	and	CC
cord-310847-63gh2tg4	881	69	applications	application	NNS
cord-310847-63gh2tg4	881	70	in	in	IN
cord-310847-63gh2tg4	881	71	the	the	DT
cord-310847-63gh2tg4	881	72	biopharmaceutical	biopharmaceutical	JJ
cord-310847-63gh2tg4	881	73	,	,	,
cord-310847-63gh2tg4	881	74	biomedical	biomedical	JJ
cord-310847-63gh2tg4	881	75	and	and	CC
cord-310847-63gh2tg4	881	76	food	food	NN
cord-310847-63gh2tg4	881	77	industries	industry	NNS
cord-310847-63gh2tg4	881	78	New	new	JJ
cord-310847-63gh2tg4	881	79	biological	biological	JJ
cord-310847-63gh2tg4	881	80	functions	function	NNS
cord-310847-63gh2tg4	881	81	and	and	CC
cord-310847-63gh2tg4	881	82	applications	application	NNS
cord-310847-63gh2tg4	881	83	of	of	IN
cord-310847-63gh2tg4	881	84	high	high	JJ
cord-310847-63gh2tg4	881	85	-	-	HYPH
cord-310847-63gh2tg4	881	86	molecular	molecular	JJ
cord-310847-63gh2tg4	881	87	-	-	HYPH
cord-310847-63gh2tg4	881	88	mass	mass	NN
cord-310847-63gh2tg4	881	89	poly	poly	JJ
cord-310847-63gh2tg4	881	90	-	-	HYPH
cord-310847-63gh2tg4	881	91	gamma	gamma	NN
cord-310847-63gh2tg4	881	92	-	-	HYPH
cord-310847-63gh2tg4	881	93	glutamic	glutamic	NN
cord-310847-63gh2tg4	881	94	acid	acid	NN
cord-310847-63gh2tg4	881	95	Review	Review	NNP
cord-310847-63gh2tg4	881	96	on	on	IN
cord-310847-63gh2tg4	881	97	Medusa	Medusa	NNP
cord-310847-63gh2tg4	881	98	:	:	:
cord-310847-63gh2tg4	881	99	a	a	DT
cord-310847-63gh2tg4	881	100	polymer	polymer	NN
cord-310847-63gh2tg4	881	101	-	-	HYPH
cord-310847-63gh2tg4	881	102	based	base	VBN
cord-310847-63gh2tg4	881	103	sustained	sustained	JJ
cord-310847-63gh2tg4	881	104	release	release	NN
cord-310847-63gh2tg4	881	105	technology	technology	NN
cord-310847-63gh2tg4	881	106	for	for	IN
cord-310847-63gh2tg4	881	107	protein	protein	NN
cord-310847-63gh2tg4	881	108	and	and	CC
cord-310847-63gh2tg4	881	109	peptide	peptide	JJ
cord-310847-63gh2tg4	881	110	drugs	drug	NNS
cord-310847-63gh2tg4	881	111	Biomedical	Biomedical	NNP
cord-310847-63gh2tg4	881	112	applications	application	NNS
cord-310847-63gh2tg4	881	113	of	of	IN
cord-310847-63gh2tg4	881	114	chemically	chemically	RB
cord-310847-63gh2tg4	881	115	and	and	CC
cord-310847-63gh2tg4	881	116	microbiologically	microbiologically	RB
cord-310847-63gh2tg4	881	117	synthesized	synthesize	VBN
cord-310847-63gh2tg4	881	118	poly(glutamic	poly(glutamic	JJ
cord-310847-63gh2tg4	881	119	acid	acid	NN
cord-310847-63gh2tg4	881	120	)	)	-RRB-
cord-310847-63gh2tg4	881	121	and	and	CC
cord-310847-63gh2tg4	881	122	poly(lysine	poly(lysine	NN
cord-310847-63gh2tg4	881	123	)	)	-RRB-
cord-310847-63gh2tg4	882	1	Production	production	NN
cord-310847-63gh2tg4	882	2	and	and	CC
cord-310847-63gh2tg4	882	3	characterization	characterization	NN
cord-310847-63gh2tg4	882	4	of	of	IN
cord-310847-63gh2tg4	882	5	gamma	gamma	JJ
cord-310847-63gh2tg4	882	6	-	-	HYPH
cord-310847-63gh2tg4	882	7	polyglutamic	polyglutamic	JJ
cord-310847-63gh2tg4	882	8	acid	acid	NN
cord-310847-63gh2tg4	882	9	nanoparticles	nanoparticle	NNS
cord-310847-63gh2tg4	882	10	for	for	IN
cord-310847-63gh2tg4	882	11	controlled	control	VBN
cord-310847-63gh2tg4	882	12	anticancer	anticancer	JJ
cord-310847-63gh2tg4	882	13	drug	drug	NN
cord-310847-63gh2tg4	882	14	release	release	NN
cord-310847-63gh2tg4	882	15	Biological	biological	JJ
cord-310847-63gh2tg4	882	16	and	and	CC
cord-310847-63gh2tg4	882	17	clinical	clinical	JJ
cord-310847-63gh2tg4	882	18	characterization	characterization	NN
cord-310847-63gh2tg4	882	19	of	of	IN
cord-310847-63gh2tg4	882	20	paclitaxel	paclitaxel	NNP
cord-310847-63gh2tg4	882	21	poliglumex	poliglumex	NNP
cord-310847-63gh2tg4	882	22	(	(	-LRB-
cord-310847-63gh2tg4	882	23	PPX	PPX	NNP
cord-310847-63gh2tg4	882	24	,	,	,
cord-310847-63gh2tg4	882	25	CT-2103	CT-2103	NNP
cord-310847-63gh2tg4	882	26	)	)	-RRB-
cord-310847-63gh2tg4	882	27	,	,	,
cord-310847-63gh2tg4	882	28	a	a	DT
cord-310847-63gh2tg4	882	29	macromolecular	macromolecular	JJ
cord-310847-63gh2tg4	882	30	polymer	polymer	NN
cord-310847-63gh2tg4	882	31	-	-	HYPH
cord-310847-63gh2tg4	882	32	drug	drug	NN
cord-310847-63gh2tg4	882	33	conjugate	conjugate	NN
cord-310847-63gh2tg4	882	34	PEST	pest	NN
cord-310847-63gh2tg4	882	35	sequences	sequence	NNS
cord-310847-63gh2tg4	882	36	and	and	CC
cord-310847-63gh2tg4	882	37	regulation	regulation	NN
cord-310847-63gh2tg4	882	38	by	by	IN
cord-310847-63gh2tg4	882	39	proteolysis	proteolysis	NN
cord-310847-63gh2tg4	882	40	Amino	amino	NN
cord-310847-63gh2tg4	882	41	acid	acid	NN
cord-310847-63gh2tg4	882	42	sequences	sequence	NNS
cord-310847-63gh2tg4	882	43	common	common	JJ
cord-310847-63gh2tg4	882	44	to	to	TO
cord-310847-63gh2tg4	882	45	rapidly	rapidly	RB
cord-310847-63gh2tg4	882	46	degraded	degrade	VBN
cord-310847-63gh2tg4	882	47	proteins	protein	NNS
cord-310847-63gh2tg4	883	1	:	:	:
cord-310847-63gh2tg4	883	2	the	the	DT
cord-310847-63gh2tg4	883	3	PEST	PEST	NNP
cord-310847-63gh2tg4	883	4	hypothesis	hypothesis	NN
cord-310847-63gh2tg4	884	1	Intrinsic	intrinsic	JJ
cord-310847-63gh2tg4	884	2	unstructuredness	unstructuredness	NN
cord-310847-63gh2tg4	884	3	and	and	CC
cord-310847-63gh2tg4	884	4	abundance	abundance	NN
cord-310847-63gh2tg4	884	5	of	of	IN
cord-310847-63gh2tg4	884	6	PEST	pest	NN
cord-310847-63gh2tg4	884	7	motifs	motif	NNS
cord-310847-63gh2tg4	884	8	in	in	IN
cord-310847-63gh2tg4	884	9	eukaryotic	eukaryotic	JJ
cord-310847-63gh2tg4	884	10	proteomes	proteome	NNS
cord-310847-63gh2tg4	884	11	Coupling	Coupling	NNP
cord-310847-63gh2tg4	884	12	caspase	caspase	NN
cord-310847-63gh2tg4	884	13	cleavage	cleavage	NN
cord-310847-63gh2tg4	884	14	and	and	CC
cord-310847-63gh2tg4	884	15	proteasomal	proteasomal	JJ
cord-310847-63gh2tg4	884	16	degradation	degradation	NN
cord-310847-63gh2tg4	884	17	of	of	IN
cord-310847-63gh2tg4	884	18	proteins	protein	NNS
cord-310847-63gh2tg4	884	19	carrying	carry	VBG
cord-310847-63gh2tg4	884	20	PEST	PEST	NNP
cord-310847-63gh2tg4	884	21	motif	motif	NN
cord-310847-63gh2tg4	884	22	Functional	functional	JJ
cord-310847-63gh2tg4	884	23	protein	protein	NN
cord-310847-63gh2tg4	884	24	domains	domain	NNS
cord-310847-63gh2tg4	884	25	from	from	IN
cord-310847-63gh2tg4	884	26	the	the	DT
cord-310847-63gh2tg4	884	27	thermally	thermally	RB
cord-310847-63gh2tg4	884	28	driven	drive	VBN
cord-310847-63gh2tg4	884	29	motion	motion	NN
cord-310847-63gh2tg4	884	30	of	of	IN
cord-310847-63gh2tg4	884	31	polypeptide	polypeptide	NN
cord-310847-63gh2tg4	884	32	chains	chain	NNS
cord-310847-63gh2tg4	884	33	:	:	:
cord-310847-63gh2tg4	884	34	a	a	DT
cord-310847-63gh2tg4	884	35	proposal	proposal	NN
cord-310847-63gh2tg4	884	36	Entropic	entropic	JJ
cord-310847-63gh2tg4	884	37	exclusion	exclusion	NN
cord-310847-63gh2tg4	884	38	by	by	IN
cord-310847-63gh2tg4	884	39	neurofilament	neurofilament	NNP
cord-310847-63gh2tg4	884	40	sidearms	sidearm	NNS
cord-310847-63gh2tg4	884	41	:	:	:
cord-310847-63gh2tg4	884	42	a	a	DT
cord-310847-63gh2tg4	884	43	mechanism	mechanism	NN
cord-310847-63gh2tg4	884	44	for	for	IN
cord-310847-63gh2tg4	884	45	maintaining	maintain	VBG
cord-310847-63gh2tg4	884	46	interfilament	interfilament	JJ
cord-310847-63gh2tg4	884	47	spacing	space	VBG
cord-310847-63gh2tg4	884	48	Hybrid	hybrid	JJ
cord-310847-63gh2tg4	884	49	character	character	NN
cord-310847-63gh2tg4	884	50	of	of	IN
cord-310847-63gh2tg4	884	51	a	a	DT
cord-310847-63gh2tg4	884	52	large	large	JJ
cord-310847-63gh2tg4	884	53	neurofilament	neurofilament	JJ
cord-310847-63gh2tg4	884	54	protein	protein	NN
cord-310847-63gh2tg4	884	55	(	(	-LRB-
cord-310847-63gh2tg4	884	56	NF	NF	NNP
cord-310847-63gh2tg4	884	57	-	-	HYPH
cord-310847-63gh2tg4	884	58	M	M	NNP
cord-310847-63gh2tg4	884	59	)	)	-RRB-
cord-310847-63gh2tg4	884	60	:	:	:
cord-310847-63gh2tg4	884	61	intermediate	intermediate	JJ
cord-310847-63gh2tg4	884	62	filament	filament	NN
cord-310847-63gh2tg4	884	63	type	type	NN
cord-310847-63gh2tg4	884	64	sequence	sequence	NN
cord-310847-63gh2tg4	884	65	followed	follow	VBN
cord-310847-63gh2tg4	884	66	by	by	IN
cord-310847-63gh2tg4	884	67	a	a	DT
cord-310847-63gh2tg4	884	68	long	long	JJ
cord-310847-63gh2tg4	884	69	and	and	CC
cord-310847-63gh2tg4	884	70	acidic	acidic	JJ
cord-310847-63gh2tg4	884	71	carboxy	carboxy	JJ
cord-310847-63gh2tg4	884	72	-	-	HYPH
cord-310847-63gh2tg4	884	73	terminal	terminal	NN
cord-310847-63gh2tg4	884	74	extension	extension	NN
cord-310847-63gh2tg4	884	75	Electron	electron	NN
cord-310847-63gh2tg4	884	76	microscopy	microscopy	NN
cord-310847-63gh2tg4	884	77	of	of	IN
cord-310847-63gh2tg4	884	78	MAP	map	NN
cord-310847-63gh2tg4	884	79	2	2	CD
cord-310847-63gh2tg4	885	1	(	(	-LRB-
cord-310847-63gh2tg4	885	2	microtubule	microtubule	NN
cord-310847-63gh2tg4	885	3	-	-	HYPH
cord-310847-63gh2tg4	885	4	associated	associate	VBN
cord-310847-63gh2tg4	885	5	protein	protein	NN
cord-310847-63gh2tg4	885	6	2	2	CD
cord-310847-63gh2tg4	885	7	)	)	-RRB-
cord-310847-63gh2tg4	886	1	A	a	DT
cord-310847-63gh2tg4	886	2	complex	complex	NN
cord-310847-63gh2tg4	886	3	of	of	IN
cord-310847-63gh2tg4	886	4	NuMA	NuMA	NNP
cord-310847-63gh2tg4	886	5	and	and	CC
cord-310847-63gh2tg4	886	6	cytoplasmic	cytoplasmic	JJ
cord-310847-63gh2tg4	886	7	dynein	dynein	NN
cord-310847-63gh2tg4	886	8	is	be	VBZ
cord-310847-63gh2tg4	886	9	essential	essential	JJ
cord-310847-63gh2tg4	886	10	for	for	IN
cord-310847-63gh2tg4	886	11	mitotic	mitotic	JJ
cord-310847-63gh2tg4	886	12	spindle	spindle	NN
cord-310847-63gh2tg4	886	13	assembly	assembly	NN
cord-310847-63gh2tg4	886	14	Sweeping	sweep	VBG
cord-310847-63gh2tg4	886	15	away	away	RP
cord-310847-63gh2tg4	886	16	protein	protein	NN
cord-310847-63gh2tg4	886	17	aggregation	aggregation	NN
cord-310847-63gh2tg4	886	18	with	with	IN
cord-310847-63gh2tg4	886	19	entropic	entropic	JJ
cord-310847-63gh2tg4	886	20	bristles	bristle	NNS
cord-310847-63gh2tg4	886	21	:	:	:
cord-310847-63gh2tg4	887	1	intrinsically	intrinsically	RB
cord-310847-63gh2tg4	887	2	disordered	disordered	JJ
cord-310847-63gh2tg4	887	3	protein	protein	NN
cord-310847-63gh2tg4	887	4	fusions	fusion	NNS
cord-310847-63gh2tg4	887	5	enhance	enhance	VBP
cord-310847-63gh2tg4	887	6	soluble	soluble	JJ
cord-310847-63gh2tg4	887	7	expression	expression	NN
cord-310847-63gh2tg4	888	1	Conformational	Conformational	NNP
cord-310847-63gh2tg4	888	2	studies	study	NNS
cord-310847-63gh2tg4	888	3	on	on	IN
cord-310847-63gh2tg4	888	4	poly	poly	NNP
cord-310847-63gh2tg4	888	5	-	-	HYPH
cord-310847-63gh2tg4	888	6	L	l	NN
cord-310847-63gh2tg4	888	7	-	-	HYPH
cord-310847-63gh2tg4	888	8	glutamic	glutamic	NN
cord-310847-63gh2tg4	888	9	acid	acid	NN
cord-310847-63gh2tg4	888	10	and	and	CC
cord-310847-63gh2tg4	888	11	copolymers	copolymer	NNS
cord-310847-63gh2tg4	888	12	of	of	IN
cord-310847-63gh2tg4	888	13	L	l	NN
cord-310847-63gh2tg4	888	14	-	-	HYPH
cord-310847-63gh2tg4	888	15	glutamic	glutamic	NN
cord-310847-63gh2tg4	888	16	acid	acid	NN
cord-310847-63gh2tg4	888	17	and	and	CC
cord-310847-63gh2tg4	888	18	L	l	NN
cord-310847-63gh2tg4	888	19	-	-	HYPH
cord-310847-63gh2tg4	888	20	phenylalanine	phenylalanine	NNP
cord-310847-63gh2tg4	888	21	Study	Study	NNP
cord-310847-63gh2tg4	888	22	of	of	IN
cord-310847-63gh2tg4	888	23	the	the	DT
cord-310847-63gh2tg4	888	24	"	"	``
cord-310847-63gh2tg4	888	25	molten	molten	JJ
cord-310847-63gh2tg4	888	26	globule	globule	NN
cord-310847-63gh2tg4	888	27	"	"	''
cord-310847-63gh2tg4	888	28	intermediate	intermediate	JJ
cord-310847-63gh2tg4	888	29	state	state	NN
cord-310847-63gh2tg4	888	30	in	in	IN
cord-310847-63gh2tg4	888	31	protein	protein	NN
cord-310847-63gh2tg4	888	32	folding	folding	NN
cord-310847-63gh2tg4	888	33	by	by	IN
cord-310847-63gh2tg4	888	34	a	a	DT
cord-310847-63gh2tg4	888	35	hydrophobic	hydrophobic	JJ
cord-310847-63gh2tg4	888	36	fluorescent	fluorescent	NN
cord-310847-63gh2tg4	888	37	probe	probe	NN
cord-310847-63gh2tg4	888	38	Salt	Salt	NNP
cord-310847-63gh2tg4	888	39	bridge	bridge	NN
cord-310847-63gh2tg4	888	40	induced	induce	VBD
cord-310847-63gh2tg4	888	41	changes	change	NNS
cord-310847-63gh2tg4	888	42	in	in	IN
cord-310847-63gh2tg4	888	43	the	the	DT
cord-310847-63gh2tg4	888	44	secondary	secondary	JJ
cord-310847-63gh2tg4	888	45	structure	structure	NN
cord-310847-63gh2tg4	888	46	of	of	IN
cord-310847-63gh2tg4	888	47	ionic	ionic	JJ
cord-310847-63gh2tg4	888	48	polypeptides	polypeptide	NNS
cord-310847-63gh2tg4	888	49	Glutamate	Glutamate	NNP
cord-310847-63gh2tg4	888	50	racemase	racemase	NN
cord-310847-63gh2tg4	888	51	as	as	IN
cord-310847-63gh2tg4	888	52	a	a	DT
cord-310847-63gh2tg4	888	53	target	target	NN
cord-310847-63gh2tg4	888	54	for	for	IN
cord-310847-63gh2tg4	888	55	drug	drug	NN
cord-310847-63gh2tg4	888	56	discovery	discovery	NN
cord-310847-63gh2tg4	888	57	CapE	CapE	NNP
cord-310847-63gh2tg4	888	58	,	,	,
cord-310847-63gh2tg4	888	59	a	a	DT
cord-310847-63gh2tg4	888	60	47-amino	47-amino	CD
cord-310847-63gh2tg4	888	61	-	-	HYPH
cord-310847-63gh2tg4	888	62	acid	acid	NN
cord-310847-63gh2tg4	888	63	peptide	peptide	NN
cord-310847-63gh2tg4	888	64	,	,	,
cord-310847-63gh2tg4	888	65	is	be	VBZ
cord-310847-63gh2tg4	888	66	necessary	necessary	JJ
cord-310847-63gh2tg4	888	67	for	for	IN
cord-310847-63gh2tg4	888	68	Bacillus	Bacillus	NNP
cord-310847-63gh2tg4	888	69	anthracis	anthracis	NN
cord-310847-63gh2tg4	888	70	polyglutamate	polyglutamate	NNP
cord-310847-63gh2tg4	888	71	capsule	capsule	NN
cord-310847-63gh2tg4	888	72	synthesis	synthesis	NN
cord-310847-63gh2tg4	889	1	Fusobacterium	fusobacterium	NN
cord-310847-63gh2tg4	889	2	nucleatum	nucleatum	NN
cord-310847-63gh2tg4	889	3	,	,	,
cord-310847-63gh2tg4	889	4	the	the	DT
cord-310847-63gh2tg4	889	5	first	first	JJ
cord-310847-63gh2tg4	889	6	Gram	gram	NN
cord-310847-63gh2tg4	889	7	-	-	HYPH
cord-310847-63gh2tg4	889	8	negative	negative	JJ
cord-310847-63gh2tg4	889	9	bacterium	bacterium	NN
cord-310847-63gh2tg4	889	10	demonstrated	demonstrate	VBN
cord-310847-63gh2tg4	889	11	to	to	TO
cord-310847-63gh2tg4	889	12	produce	produce	VB
cord-310847-63gh2tg4	889	13	polyglutamate	polyglutamate	NNP
cord-310847-63gh2tg4	889	14	Ueber	Ueber	NNP
cord-310847-63gh2tg4	889	15	ein	ein	NNP
cord-310847-63gh2tg4	889	16	spezifisches	spezifisches	NNP
cord-310847-63gh2tg4	889	17	Protein	Protein	NNP
cord-310847-63gh2tg4	889	18	der	der	NNP
cord-310847-63gh2tg4	889	19	Kapsel	Kapsel	NNP
cord-310847-63gh2tg4	889	20	des	des	FW
cord-310847-63gh2tg4	889	21	Milzbrandbazillus	Milzbrandbazillus	NNP
cord-310847-63gh2tg4	889	22	Key	key	JJ
cord-310847-63gh2tg4	889	23	role	role	NN
cord-310847-63gh2tg4	889	24	of	of	IN
cord-310847-63gh2tg4	889	25	poly	poly	JJ
cord-310847-63gh2tg4	889	26	-	-	HYPH
cord-310847-63gh2tg4	889	27	gamma	gamma	JJ
cord-310847-63gh2tg4	889	28	-	-	HYPH
cord-310847-63gh2tg4	889	29	DL	dl	NN
cord-310847-63gh2tg4	889	30	-	-	HYPH
cord-310847-63gh2tg4	889	31	glutamic	glutamic	NN
cord-310847-63gh2tg4	889	32	acid	acid	NN
cord-310847-63gh2tg4	889	33	in	in	IN
cord-310847-63gh2tg4	889	34	immune	immune	JJ
cord-310847-63gh2tg4	889	35	evasion	evasion	NN
cord-310847-63gh2tg4	889	36	and	and	CC
cord-310847-63gh2tg4	889	37	virulence	virulence	NN
cord-310847-63gh2tg4	889	38	of	of	IN
cord-310847-63gh2tg4	889	39	Staphylococcus	Staphylococcus	NNP
cord-310847-63gh2tg4	889	40	epidermidis	epidermidis	NN
cord-310847-63gh2tg4	889	41	Polyglutamic	Polyglutamic	NNP
cord-310847-63gh2tg4	889	42	acid	acid	NN
cord-310847-63gh2tg4	889	43	from	from	IN
cord-310847-63gh2tg4	889	44	Bacillus	Bacillus	NNP
cord-310847-63gh2tg4	889	45	anthracis	anthracis	NN
cord-310847-63gh2tg4	889	46	grown	grow	VBN
cord-310847-63gh2tg4	889	47	in	in	IN
cord-310847-63gh2tg4	889	48	vivo	vivo	NN
cord-310847-63gh2tg4	889	49	;	;	:
cord-310847-63gh2tg4	889	50	structure	structure	NN
cord-310847-63gh2tg4	889	51	and	and	CC
cord-310847-63gh2tg4	889	52	aggressin	aggressin	NNP
cord-310847-63gh2tg4	889	53	activity	activity	NN
cord-310847-63gh2tg4	889	54	Metal	metal	NN
cord-310847-63gh2tg4	889	55	-	-	HYPH
cord-310847-63gh2tg4	889	56	binding	bind	VBG
cord-310847-63gh2tg4	889	57	characteristics	characteristic	NNS
cord-310847-63gh2tg4	889	58	of	of	IN
cord-310847-63gh2tg4	889	59	the	the	DT
cord-310847-63gh2tg4	889	60	gamma	gamma	NN
cord-310847-63gh2tg4	889	61	-	-	HYPH
cord-310847-63gh2tg4	889	62	glutamyl	glutamyl	JJ
cord-310847-63gh2tg4	889	63	capsular	capsular	NN
cord-310847-63gh2tg4	889	64	polymer	polymer	NN
cord-310847-63gh2tg4	889	65	of	of	IN
cord-310847-63gh2tg4	889	66	Bacillus	Bacillus	NNP
cord-310847-63gh2tg4	889	67	licheniformis	licheniformis	NN
cord-310847-63gh2tg4	889	68	ATCC	ATCC	NNP
cord-310847-63gh2tg4	890	1	9945	9945	CD
cord-310847-63gh2tg4	891	1	Characterization	characterization	NN
cord-310847-63gh2tg4	891	2	of	of	IN
cord-310847-63gh2tg4	891	3	Bacillus	bacillus	NN
cord-310847-63gh2tg4	891	4	subtilis	subtili	NNS
cord-310847-63gh2tg4	891	5	gamma	gamma	NN
cord-310847-63gh2tg4	891	6	-	-	HYPH
cord-310847-63gh2tg4	891	7	glutamyltransferase	glutamyltransferase	NN
cord-310847-63gh2tg4	891	8	and	and	CC
cord-310847-63gh2tg4	891	9	its	-PRON-	PRP$
cord-310847-63gh2tg4	891	10	involvement	involvement	NN
cord-310847-63gh2tg4	891	11	in	in	IN
cord-310847-63gh2tg4	891	12	the	the	DT
cord-310847-63gh2tg4	891	13	degradation	degradation	NN
cord-310847-63gh2tg4	891	14	of	of	IN
cord-310847-63gh2tg4	891	15	capsule	capsule	NN
cord-310847-63gh2tg4	891	16	polygamma	polygamma	JJ
cord-310847-63gh2tg4	891	17	-	-	HYPH
cord-310847-63gh2tg4	891	18	glutamate	glutamate	NN
cord-310847-63gh2tg4	891	19	Occurrence	occurrence	NN
cord-310847-63gh2tg4	891	20	of	of	IN
cord-310847-63gh2tg4	891	21	Poly	Poly	NNP
cord-310847-63gh2tg4	891	22	-	-	HYPH
cord-310847-63gh2tg4	891	23	γ	γ	NNP
cord-310847-63gh2tg4	891	24	-	-	HYPH
cord-310847-63gh2tg4	891	25	D	D	NNP
cord-310847-63gh2tg4	891	26	-	-	HYPH
cord-310847-63gh2tg4	891	27	Glutamic	glutamic	NN
cord-310847-63gh2tg4	891	28	Acid	Acid	NNP
cord-310847-63gh2tg4	891	29	and	and	CC
cord-310847-63gh2tg4	891	30	Poly	Poly	NNP
cord-310847-63gh2tg4	891	31	-	-	HYPH
cord-310847-63gh2tg4	891	32	α	α	NNP
cord-310847-63gh2tg4	891	33	-	-	HYPH
cord-310847-63gh2tg4	891	34	L	l	NN
cord-310847-63gh2tg4	891	35	-	-	HYPH
cord-310847-63gh2tg4	891	36	Glutamine	glutamine	NN
cord-310847-63gh2tg4	891	37	in	in	IN
cord-310847-63gh2tg4	891	38	the	the	DT
cord-310847-63gh2tg4	891	39	Genera	Genera	NNP
cord-310847-63gh2tg4	891	40	Xanthobacter	Xanthobacter	NNP
cord-310847-63gh2tg4	891	41	,	,	,
cord-310847-63gh2tg4	891	42	Flexithrix	Flexithrix	NNP
cord-310847-63gh2tg4	891	43	,	,	,
cord-310847-63gh2tg4	891	44	Sporosarcina	Sporosarcina	NNP
cord-310847-63gh2tg4	891	45	and	and	CC
cord-310847-63gh2tg4	891	46	Planococcus	Planococcus	NNP
cord-310847-63gh2tg4	891	47	Transfer	Transfer	NNP
cord-310847-63gh2tg4	891	48	of	of	IN
cord-310847-63gh2tg4	891	49	Natrialba	Natrialba	NNP
cord-310847-63gh2tg4	891	50	asiatica	asiatica	NN
cord-310847-63gh2tg4	891	51	B1	b1	NN
cord-310847-63gh2tg4	891	52	T	T	NNP
cord-310847-63gh2tg4	891	53	to	to	IN
cord-310847-63gh2tg4	891	54	Natrialba	Natrialba	NNP
cord-310847-63gh2tg4	891	55	taiwanensis	taiwanensis	NN
cord-310847-63gh2tg4	891	56	sp	sp	NNP
cord-310847-63gh2tg4	891	57	.	.	.
cord-310847-63gh2tg4	892	1	nov	nov	NNP
cord-310847-63gh2tg4	892	2	.	.	.
cord-310847-63gh2tg4	893	1	and	and	CC
cord-310847-63gh2tg4	893	2	description	description	NN
cord-310847-63gh2tg4	893	3	of	of	IN
cord-310847-63gh2tg4	893	4	Natrialba	Natrialba	NNP
cord-310847-63gh2tg4	893	5	aegyptiaca	aegyptiaca	NN
cord-310847-63gh2tg4	893	6	sp	sp	NN
cord-310847-63gh2tg4	893	7	.	.	.
cord-310847-63gh2tg4	894	1	nov	nov	NNP
cord-310847-63gh2tg4	894	2	.	.	NNP
cord-310847-63gh2tg4	894	3	,	,	,
cord-310847-63gh2tg4	894	4	a	a	DT
cord-310847-63gh2tg4	894	5	novel	novel	NN
cord-310847-63gh2tg4	894	6	extremely	extremely	RB
cord-310847-63gh2tg4	894	7	halophilic	halophilic	JJ
cord-310847-63gh2tg4	894	8	,	,	,
cord-310847-63gh2tg4	894	9	aerobic	aerobic	JJ
cord-310847-63gh2tg4	894	10	,	,	,
cord-310847-63gh2tg4	894	11	nonpigmented	nonpigmented	JJ
cord-310847-63gh2tg4	894	12	member	member	NN
cord-310847-63gh2tg4	894	13	of	of	IN
cord-310847-63gh2tg4	894	14	the	the	DT
cord-310847-63gh2tg4	894	15	Archaea	Archaea	NNP
cord-310847-63gh2tg4	894	16	from	from	IN
cord-310847-63gh2tg4	894	17	Egypt	Egypt	NNP
cord-310847-63gh2tg4	894	18	that	that	WDT
cord-310847-63gh2tg4	894	19	produces	produce	VBZ
cord-310847-63gh2tg4	894	20	extracellular	extracellular	JJ
cord-310847-63gh2tg4	894	21	poly(glutamic	poly(glutamic	CD
cord-310847-63gh2tg4	894	22	acid	acid	NN
cord-310847-63gh2tg4	894	23	)	)	-RRB-
cord-310847-63gh2tg4	895	1	Poly(gamma	Poly(gamma	NNP
cord-310847-63gh2tg4	895	2	-	-	HYPH
cord-310847-63gh2tg4	895	3	glutamic	glutamic	NNP
cord-310847-63gh2tg4	895	4	acid)s	acid)s	NNP
cord-310847-63gh2tg4	895	5	are	be	VBP
cord-310847-63gh2tg4	895	6	the	the	DT
cord-310847-63gh2tg4	895	7	major	major	JJ
cord-310847-63gh2tg4	895	8	constituents	constituent	NNS
cord-310847-63gh2tg4	895	9	of	of	IN
cord-310847-63gh2tg4	895	10	nematocysts	nematocyst	NNS
cord-310847-63gh2tg4	895	11	in	in	IN
cord-310847-63gh2tg4	895	12	Hydra	Hydra	NNP
cord-310847-63gh2tg4	895	13	(	(	-LRB-
cord-310847-63gh2tg4	895	14	Hydrozoa	Hydrozoa	NNP
cord-310847-63gh2tg4	895	15	,	,	,
cord-310847-63gh2tg4	895	16	Cnidaria	Cnidaria	NNP
cord-310847-63gh2tg4	895	17	)	)	-RRB-
cord-310847-63gh2tg4	895	18	Microbial	microbial	JJ
cord-310847-63gh2tg4	895	19	degradation	degradation	NN
cord-310847-63gh2tg4	895	20	of	of	IN
cord-310847-63gh2tg4	895	21	poly(amino	poly(amino	NN
cord-310847-63gh2tg4	895	22	acid)s	acid)s	CD
cord-310847-63gh2tg4	895	23	Poly	Poly	NNP
cord-310847-63gh2tg4	895	24	(	(	-LRB-
cord-310847-63gh2tg4	895	25	glutamic	glutamic	NN
cord-310847-63gh2tg4	895	26	acid)--an	acid)--an	NN
cord-310847-63gh2tg4	895	27	emerging	emerge	VBG
cord-310847-63gh2tg4	895	28	biopolymer	biopolymer	NN
cord-310847-63gh2tg4	895	29	of	of	IN
cord-310847-63gh2tg4	895	30	commercial	commercial	JJ
cord-310847-63gh2tg4	895	31	interest	interest	NN
cord-310847-63gh2tg4	895	32	Cloning	cloning	NN
cord-310847-63gh2tg4	895	33	and	and	CC
cord-310847-63gh2tg4	895	34	characterization	characterization	NN
cord-310847-63gh2tg4	895	35	of	of	IN
cord-310847-63gh2tg4	895	36	a	a	DT
cord-310847-63gh2tg4	895	37	novel	novel	JJ
cord-310847-63gh2tg4	895	38	trinucleotide	trinucleotide	NNP
cord-310847-63gh2tg4	895	39	repeat	repeat	NN
cord-310847-63gh2tg4	895	40	-	-	HYPH
cord-310847-63gh2tg4	895	41	containing	contain	VBG
cord-310847-63gh2tg4	895	42	gene	gene	NN
cord-310847-63gh2tg4	895	43	GARP	GARP	NNP
cord-310847-63gh2tg4	895	44	from	from	IN
cord-310847-63gh2tg4	895	45	Euplotes	Euplotes	NNP
cord-310847-63gh2tg4	895	46	octocarinatus	octocarinatus	NNP
cord-310847-63gh2tg4	895	47	Structure	Structure	NNP
cord-310847-63gh2tg4	895	48	of	of	IN
cord-310847-63gh2tg4	895	49	a	a	DT
cord-310847-63gh2tg4	895	50	Plasmodium	Plasmodium	NNP
cord-310847-63gh2tg4	895	51	falciparum	falciparum	NN
cord-310847-63gh2tg4	895	52	gene	gene	NN
cord-310847-63gh2tg4	895	53	that	that	WDT
cord-310847-63gh2tg4	895	54	encodes	encode	VBZ
cord-310847-63gh2tg4	895	55	a	a	DT
cord-310847-63gh2tg4	895	56	glutamic	glutamic	NN
cord-310847-63gh2tg4	895	57	acid	acid	NN
cord-310847-63gh2tg4	895	58	-	-	HYPH
cord-310847-63gh2tg4	895	59	rich	rich	JJ
cord-310847-63gh2tg4	895	60	protein	protein	NN
cord-310847-63gh2tg4	895	61	(	(	-LRB-
cord-310847-63gh2tg4	895	62	GARP	GARP	NNP
cord-310847-63gh2tg4	895	63	)	)	-RRB-
cord-310847-63gh2tg4	896	1	A	a	DT
cord-310847-63gh2tg4	896	2	novel	novel	JJ
cord-310847-63gh2tg4	896	3	PEPP	PEPP	NNP
cord-310847-63gh2tg4	896	4	homeobox	homeobox	NN
cord-310847-63gh2tg4	896	5	gene	gene	NN
cord-310847-63gh2tg4	896	6	,	,	,
cord-310847-63gh2tg4	896	7	TOX	TOX	NNP
cord-310847-63gh2tg4	896	8	,	,	,
cord-310847-63gh2tg4	896	9	is	be	VBZ
cord-310847-63gh2tg4	896	10	highly	highly	RB
cord-310847-63gh2tg4	896	11	glutamic	glutamic	JJ
cord-310847-63gh2tg4	896	12	acid	acid	NN
cord-310847-63gh2tg4	896	13	rich	rich	JJ
cord-310847-63gh2tg4	896	14	and	and	CC
cord-310847-63gh2tg4	896	15	specifically	specifically	RB
cord-310847-63gh2tg4	896	16	expressed	express	VBN
cord-310847-63gh2tg4	896	17	in	in	IN
cord-310847-63gh2tg4	896	18	murine	murine	JJ
cord-310847-63gh2tg4	896	19	testis	testis	NN
cord-310847-63gh2tg4	896	20	and	and	CC
cord-310847-63gh2tg4	896	21	ovary	ovary	NN
cord-310847-63gh2tg4	896	22	Kibra	Kibra	NNP
cord-310847-63gh2tg4	896	23	functions	function	NNS
cord-310847-63gh2tg4	896	24	as	as	IN
cord-310847-63gh2tg4	896	25	a	a	DT
cord-310847-63gh2tg4	896	26	tumor	tumor	NN
cord-310847-63gh2tg4	896	27	suppressor	suppressor	NN
cord-310847-63gh2tg4	896	28	protein	protein	NN
cord-310847-63gh2tg4	896	29	that	that	WDT
cord-310847-63gh2tg4	896	30	regulates	regulate	VBZ
cord-310847-63gh2tg4	896	31	Hippo	Hippo	NNP
cord-310847-63gh2tg4	896	32	signaling	signal	VBG
cord-310847-63gh2tg4	896	33	in	in	IN
cord-310847-63gh2tg4	896	34	conjunction	conjunction	NN
cord-310847-63gh2tg4	896	35	with	with	IN
cord-310847-63gh2tg4	896	36	Merlin	Merlin	NNP
cord-310847-63gh2tg4	896	37	and	and	CC
cord-310847-63gh2tg4	896	38	Expanded	Expanded	NNP
cord-310847-63gh2tg4	896	39	Kibra	Kibra	NNP
cord-310847-63gh2tg4	896	40	is	be	VBZ
cord-310847-63gh2tg4	896	41	a	a	DT
cord-310847-63gh2tg4	896	42	regulator	regulator	NN
cord-310847-63gh2tg4	896	43	of	of	IN
cord-310847-63gh2tg4	896	44	the	the	DT
cord-310847-63gh2tg4	896	45	Salvador	Salvador	NNP
cord-310847-63gh2tg4	896	46	/	/	SYM
cord-310847-63gh2tg4	896	47	Warts/	Warts/	NNP
cord-310847-63gh2tg4	896	48	Hippo	Hippo	NNP
cord-310847-63gh2tg4	896	49	signaling	signal	VBG
cord-310847-63gh2tg4	896	50	network	network	NN
cord-310847-63gh2tg4	896	51	Characterization	characterization	NN
cord-310847-63gh2tg4	896	52	of	of	IN
cord-310847-63gh2tg4	896	53	KIBRA	KIBRA	NNP
cord-310847-63gh2tg4	896	54	,	,	,
cord-310847-63gh2tg4	897	1	a	a	DT
cord-310847-63gh2tg4	897	2	novel	novel	JJ
cord-310847-63gh2tg4	897	3	WW	WW	NNP
cord-310847-63gh2tg4	897	4	domain	domain	NN
cord-310847-63gh2tg4	897	5	-	-	HYPH
cord-310847-63gh2tg4	897	6	containing	contain	VBG
cord-310847-63gh2tg4	897	7	protein	protein	NN
cord-310847-63gh2tg4	897	8	KIBRA	KIBRA	NNP
cord-310847-63gh2tg4	897	9	is	be	VBZ
cord-310847-63gh2tg4	897	10	a	a	DT
cord-310847-63gh2tg4	897	11	novel	novel	JJ
cord-310847-63gh2tg4	897	12	substrate	substrate	NN
cord-310847-63gh2tg4	897	13	for	for	IN
cord-310847-63gh2tg4	897	14	protein	protein	NN
cord-310847-63gh2tg4	897	15	kinase	kinase	NN
cord-310847-63gh2tg4	897	16	Czeta	Czeta	NNP
cord-310847-63gh2tg4	897	17	Temporal	temporal	JJ
cord-310847-63gh2tg4	897	18	-	-	HYPH
cord-310847-63gh2tg4	897	19	spatial	spatial	JJ
cord-310847-63gh2tg4	897	20	expression	expression	NN
cord-310847-63gh2tg4	897	21	and	and	CC
cord-310847-63gh2tg4	897	22	novel	novel	JJ
cord-310847-63gh2tg4	897	23	biochemical	biochemical	JJ
cord-310847-63gh2tg4	897	24	properties	property	NNS
cord-310847-63gh2tg4	897	25	of	of	IN
cord-310847-63gh2tg4	897	26	the	the	DT
cord-310847-63gh2tg4	897	27	memory	memory	NN
cord-310847-63gh2tg4	897	28	-	-	HYPH
cord-310847-63gh2tg4	897	29	related	relate	VBN
cord-310847-63gh2tg4	897	30	protein	protein	NN
cord-310847-63gh2tg4	897	31	KIBRA	KIBRA	NNP
cord-310847-63gh2tg4	897	32	Essential	essential	JJ
cord-310847-63gh2tg4	897	33	role	role	NN
cord-310847-63gh2tg4	897	34	of	of	IN
cord-310847-63gh2tg4	897	35	KIBRA	KIBRA	NNP
cord-310847-63gh2tg4	897	36	in	in	IN
cord-310847-63gh2tg4	897	37	co	co	JJ
cord-310847-63gh2tg4	897	38	-	-	NN
cord-310847-63gh2tg4	897	39	activator	activator	JJ
cord-310847-63gh2tg4	897	40	function	function	NN
cord-310847-63gh2tg4	897	41	of	of	IN
cord-310847-63gh2tg4	897	42	dynein	dynein	JJ
cord-310847-63gh2tg4	897	43	light	light	JJ
cord-310847-63gh2tg4	897	44	chain	chain	NN
cord-310847-63gh2tg4	897	45	1	1	CD
cord-310847-63gh2tg4	897	46	in	in	IN
cord-310847-63gh2tg4	897	47	mammalian	mammalian	JJ
cord-310847-63gh2tg4	897	48	cells	cell	NNS
cord-310847-63gh2tg4	897	49	KIBRA	KIBRA	NNP
cord-310847-63gh2tg4	897	50	interacts	interact	VBZ
cord-310847-63gh2tg4	897	51	with	with	IN
cord-310847-63gh2tg4	897	52	discoidin	discoidin	NNP
cord-310847-63gh2tg4	897	53	domain	domain	NN
cord-310847-63gh2tg4	897	54	receptor	receptor	NN
cord-310847-63gh2tg4	897	55	1	1	CD
cord-310847-63gh2tg4	897	56	to	to	TO
cord-310847-63gh2tg4	897	57	modulate	modulate	VB
cord-310847-63gh2tg4	898	1	collagen	collagen	NN
cord-310847-63gh2tg4	898	2	-	-	HYPH
cord-310847-63gh2tg4	898	3	induced	induce	VBN
cord-310847-63gh2tg4	898	4	signalling	signal	VBG
cord-310847-63gh2tg4	898	5	KIBRA	KIBRA	NNP
cord-310847-63gh2tg4	898	6	modulates	modulate	VBZ
cord-310847-63gh2tg4	898	7	directional	directional	JJ
cord-310847-63gh2tg4	898	8	migration	migration	NN
cord-310847-63gh2tg4	898	9	of	of	IN
cord-310847-63gh2tg4	898	10	podocytes	podocyte	NNS
cord-310847-63gh2tg4	898	11	Cloning	clone	VBG
cord-310847-63gh2tg4	898	12	a	a	DT
cord-310847-63gh2tg4	898	13	new	new	JJ
cord-310847-63gh2tg4	898	14	human	human	JJ
cord-310847-63gh2tg4	898	15	gene	gene	NN
cord-310847-63gh2tg4	898	16	from	from	IN
cord-310847-63gh2tg4	898	17	chromosome	chromosome	NN
cord-310847-63gh2tg4	899	1	21q22.3	21q22.3	CD
cord-310847-63gh2tg4	900	1	encoding	encode	VBG
cord-310847-63gh2tg4	900	2	a	a	DT
cord-310847-63gh2tg4	900	3	glutamic	glutamic	JJ
cord-310847-63gh2tg4	900	4	acid	acid	NN
cord-310847-63gh2tg4	900	5	-	-	HYPH
cord-310847-63gh2tg4	900	6	rich	rich	JJ
cord-310847-63gh2tg4	900	7	protein	protein	NN
cord-310847-63gh2tg4	900	8	expressed	express	VBN
cord-310847-63gh2tg4	900	9	in	in	IN
cord-310847-63gh2tg4	900	10	heart	heart	NN
cord-310847-63gh2tg4	900	11	and	and	CC
cord-310847-63gh2tg4	900	12	skeletal	skeletal	JJ
cord-310847-63gh2tg4	900	13	muscle	muscle	NN
cord-310847-63gh2tg4	901	1	The	the	DT
cord-310847-63gh2tg4	901	2	identification	identification	NN
cord-310847-63gh2tg4	901	3	of	of	IN
cord-310847-63gh2tg4	901	4	a	a	DT
cord-310847-63gh2tg4	901	5	novel	novel	JJ
cord-310847-63gh2tg4	901	6	human	human	JJ
cord-310847-63gh2tg4	901	7	homologue	homologue	NN
cord-310847-63gh2tg4	901	8	of	of	IN
cord-310847-63gh2tg4	901	9	the	the	DT
cord-310847-63gh2tg4	901	10	SH3	SH3	NNP
cord-310847-63gh2tg4	901	11	binding	bind	VBG
cord-310847-63gh2tg4	901	12	glutamic	glutamic	NN
cord-310847-63gh2tg4	901	13	acid	acid	NN
cord-310847-63gh2tg4	901	14	-	-	HYPH
cord-310847-63gh2tg4	901	15	rich	rich	JJ
cord-310847-63gh2tg4	901	16	(	(	-LRB-
cord-310847-63gh2tg4	901	17	SH3BGR	sh3bgr	NN
cord-310847-63gh2tg4	901	18	)	)	-RRB-
cord-310847-63gh2tg4	901	19	gene	gene	NN
cord-310847-63gh2tg4	901	20	establishes	establish	VBZ
cord-310847-63gh2tg4	901	21	a	a	DT
cord-310847-63gh2tg4	901	22	new	new	JJ
cord-310847-63gh2tg4	901	23	family	family	NN
cord-310847-63gh2tg4	901	24	of	of	IN
cord-310847-63gh2tg4	901	25	highly	highly	RB
cord-310847-63gh2tg4	901	26	conserved	conserved	JJ
cord-310847-63gh2tg4	901	27	small	small	JJ
cord-310847-63gh2tg4	901	28	proteins	protein	NNS
cord-310847-63gh2tg4	901	29	related	relate	VBN
cord-310847-63gh2tg4	901	30	to	to	IN
cord-310847-63gh2tg4	901	31	Thioredoxin	Thioredoxin	NNP
cord-310847-63gh2tg4	901	32	Superfamily	Superfamily	NNP
cord-310847-63gh2tg4	901	33	Biomarker	Biomarker	NNP
cord-310847-63gh2tg4	901	34	discovery	discovery	NN
cord-310847-63gh2tg4	901	35	:	:	:
cord-310847-63gh2tg4	901	36	a	a	DT
cord-310847-63gh2tg4	901	37	proteomic	proteomic	JJ
cord-310847-63gh2tg4	901	38	approach	approach	NN
cord-310847-63gh2tg4	901	39	for	for	IN
cord-310847-63gh2tg4	901	40	brain	brain	NN
cord-310847-63gh2tg4	901	41	cancer	cancer	NN
cord-310847-63gh2tg4	901	42	profiling	profile	VBG
cord-310847-63gh2tg4	901	43	Molecular	molecular	JJ
cord-310847-63gh2tg4	901	44	evolution	evolution	NN
cord-310847-63gh2tg4	901	45	of	of	IN
cord-310847-63gh2tg4	901	46	SPARC	SPARC	NNP
cord-310847-63gh2tg4	901	47	:	:	:
cord-310847-63gh2tg4	902	1	absence	absence	NN
cord-310847-63gh2tg4	902	2	of	of	IN
cord-310847-63gh2tg4	902	3	the	the	DT
cord-310847-63gh2tg4	902	4	acidic	acidic	JJ
cord-310847-63gh2tg4	902	5	module	module	NN
cord-310847-63gh2tg4	902	6	and	and	CC
cord-310847-63gh2tg4	902	7	expression	expression	NN
cord-310847-63gh2tg4	902	8	in	in	IN
cord-310847-63gh2tg4	902	9	the	the	DT
cord-310847-63gh2tg4	902	10	endoderm	endoderm	NNS
cord-310847-63gh2tg4	902	11	of	of	IN
cord-310847-63gh2tg4	902	12	the	the	DT
cord-310847-63gh2tg4	902	13	starlet	starlet	NN
cord-310847-63gh2tg4	902	14	sea	sea	NN
cord-310847-63gh2tg4	902	15	anemone	anemone	NN
cord-310847-63gh2tg4	902	16	NBP-45	NBP-45	NNP
cord-310847-63gh2tg4	902	17	,	,	,
cord-310847-63gh2tg4	902	18	a	a	DT
cord-310847-63gh2tg4	902	19	novel	novel	JJ
cord-310847-63gh2tg4	902	20	nucleosomal	nucleosomal	NN
cord-310847-63gh2tg4	902	21	binding	bind	VBG
cord-310847-63gh2tg4	902	22	protein	protein	NN
cord-310847-63gh2tg4	902	23	with	with	IN
cord-310847-63gh2tg4	902	24	a	a	DT
cord-310847-63gh2tg4	902	25	tissue	tissue	NN
cord-310847-63gh2tg4	902	26	-	-	HYPH
cord-310847-63gh2tg4	902	27	specific	specific	JJ
cord-310847-63gh2tg4	902	28	and	and	CC
cord-310847-63gh2tg4	902	29	developmentally	developmentally	RB
cord-310847-63gh2tg4	902	30	regulated	regulated	JJ
cord-310847-63gh2tg4	902	31	expression	expression	NN
cord-310847-63gh2tg4	903	1	The	the	DT
cord-310847-63gh2tg4	903	2	interaction	interaction	NN
cord-310847-63gh2tg4	903	3	of	of	IN
cord-310847-63gh2tg4	903	4	NSBP1	NSBP1	NNS
cord-310847-63gh2tg4	903	5	/	/	SYM
cord-310847-63gh2tg4	903	6	HMGN5	HMGN5	NNPS
cord-310847-63gh2tg4	903	7	with	with	IN
cord-310847-63gh2tg4	903	8	nucleosomes	nucleosome	NNS
cord-310847-63gh2tg4	903	9	in	in	IN
cord-310847-63gh2tg4	903	10	euchromatin	euchromatin	NN
cord-310847-63gh2tg4	903	11	counteracts	counteract	VBZ
cord-310847-63gh2tg4	903	12	linker	linker	NN
cord-310847-63gh2tg4	903	13	histone	histone	NN
cord-310847-63gh2tg4	903	14	-	-	HYPH
cord-310847-63gh2tg4	903	15	mediated	mediate	VBN
cord-310847-63gh2tg4	903	16	chromatin	chromatin	NN
cord-310847-63gh2tg4	903	17	compaction	compaction	NN
cord-310847-63gh2tg4	903	18	and	and	CC
cord-310847-63gh2tg4	903	19	modulates	modulate	VBZ
cord-310847-63gh2tg4	903	20	transcription	transcription	NN
cord-310847-63gh2tg4	903	21	Binding	binding	NN
cord-310847-63gh2tg4	903	22	of	of	IN
cord-310847-63gh2tg4	903	23	Ca2	ca2	CD
cord-310847-63gh2tg4	903	24	+	+	CC
cord-310847-63gh2tg4	903	25	to	to	IN
cord-310847-63gh2tg4	903	26	glutamic	glutamic	JJ
cord-310847-63gh2tg4	903	27	acid	acid	NN
cord-310847-63gh2tg4	903	28	-	-	HYPH
cord-310847-63gh2tg4	903	29	rich	rich	JJ
cord-310847-63gh2tg4	903	30	polypeptides	polypeptide	NNS
cord-310847-63gh2tg4	903	31	from	from	IN
cord-310847-63gh2tg4	903	32	the	the	DT
cord-310847-63gh2tg4	903	33	rod	rod	NN
cord-310847-63gh2tg4	903	34	outer	outer	JJ
cord-310847-63gh2tg4	903	35	segment	segment	NN
cord-310847-63gh2tg4	904	1	The	the	DT
cord-310847-63gh2tg4	904	2	glutamic	glutamic	NN
cord-310847-63gh2tg4	904	3	acidrich	acidrich	NNP
cord-310847-63gh2tg4	904	4	protein	protein	NN
cord-310847-63gh2tg4	904	5	is	be	VBZ
cord-310847-63gh2tg4	904	6	a	a	DT
cord-310847-63gh2tg4	904	7	gating	gate	VBG
cord-310847-63gh2tg4	904	8	inhibitor	inhibitor	NN
cord-310847-63gh2tg4	904	9	of	of	IN
cord-310847-63gh2tg4	904	10	cyclic	cyclic	JJ
cord-310847-63gh2tg4	904	11	nucleotide	nucleotide	RB
cord-310847-63gh2tg4	904	12	-	-	HYPH
cord-310847-63gh2tg4	904	13	gated	gate	VBN
cord-310847-63gh2tg4	904	14	channels	channel	NNS
cord-310847-63gh2tg4	904	15	In	in	IN
cord-310847-63gh2tg4	904	16	situ	situ	JJ
cord-310847-63gh2tg4	904	17	visualization	visualization	NN
cord-310847-63gh2tg4	904	18	of	of	IN
cord-310847-63gh2tg4	904	19	protein	protein	NN
cord-310847-63gh2tg4	904	20	interactions	interaction	NNS
cord-310847-63gh2tg4	904	21	in	in	IN
cord-310847-63gh2tg4	904	22	sensory	sensory	JJ
cord-310847-63gh2tg4	904	23	neurons	neuron	NNS
cord-310847-63gh2tg4	904	24	:	:	:
cord-310847-63gh2tg4	905	1	glutamic	glutamic	NN
cord-310847-63gh2tg4	905	2	acid	acid	NN
cord-310847-63gh2tg4	905	3	-	-	HYPH
cord-310847-63gh2tg4	905	4	rich	rich	JJ
cord-310847-63gh2tg4	905	5	proteins	protein	NNS
cord-310847-63gh2tg4	905	6	(	(	-LRB-
cord-310847-63gh2tg4	905	7	GARPs	garps	NN
cord-310847-63gh2tg4	905	8	)	)	-RRB-
cord-310847-63gh2tg4	905	9	play	play	VBP
cord-310847-63gh2tg4	905	10	differential	differential	JJ
cord-310847-63gh2tg4	905	11	roles	role	NNS
cord-310847-63gh2tg4	905	12	for	for	IN
cord-310847-63gh2tg4	905	13	photoreceptor	photoreceptor	NN
cord-310847-63gh2tg4	905	14	outer	outer	JJ
cord-310847-63gh2tg4	905	15	segment	segment	NN
cord-310847-63gh2tg4	905	16	scaffolding	scaffold	VBG
cord-310847-63gh2tg4	905	17	Age	age	NN
cord-310847-63gh2tg4	905	18	-	-	HYPH
cord-310847-63gh2tg4	905	19	related	relate	VBN
cord-310847-63gh2tg4	905	20	changes	change	NNS
cord-310847-63gh2tg4	905	21	in	in	IN
cord-310847-63gh2tg4	905	22	Cngb1-X1	Cngb1-X1	NNP
cord-310847-63gh2tg4	905	23	knockout	knockout	NN
cord-310847-63gh2tg4	905	24	mice	mouse	NNS
cord-310847-63gh2tg4	905	25	:	:	:
cord-310847-63gh2tg4	905	26	prolonged	prolong	VBN
cord-310847-63gh2tg4	905	27	cone	cone	NN
cord-310847-63gh2tg4	905	28	survival	survival	NN
cord-310847-63gh2tg4	906	1	Glutamic	glutamic	NN
cord-310847-63gh2tg4	906	2	acid	acid	NN
cord-310847-63gh2tg4	906	3	-	-	HYPH
cord-310847-63gh2tg4	906	4	rich	rich	JJ
cord-310847-63gh2tg4	906	5	proteins	protein	NNS
cord-310847-63gh2tg4	906	6	of	of	IN
cord-310847-63gh2tg4	906	7	rod	rod	NN
cord-310847-63gh2tg4	906	8	photoreceptors	photoreceptor	NNS
cord-310847-63gh2tg4	906	9	are	be	VBP
cord-310847-63gh2tg4	906	10	natively	natively	RB
cord-310847-63gh2tg4	906	11	unfolded	unfold	VBN
cord-310847-63gh2tg4	907	1	A	a	DT
cord-310847-63gh2tg4	907	2	mitochondria	mitochondria	NN
cord-310847-63gh2tg4	907	3	-	-	HYPH
cord-310847-63gh2tg4	907	4	localized	localize	VBN
cord-310847-63gh2tg4	907	5	glutamic	glutamic	NN
cord-310847-63gh2tg4	907	6	acid	acid	NN
cord-310847-63gh2tg4	907	7	-	-	HYPH
cord-310847-63gh2tg4	907	8	rich	rich	JJ
cord-310847-63gh2tg4	907	9	protein	protein	NN
cord-310847-63gh2tg4	907	10	(	(	-LRB-
cord-310847-63gh2tg4	907	11	MGARP	MGARP	NNP
cord-310847-63gh2tg4	907	12	/	/	SYM
cord-310847-63gh2tg4	907	13	OSAP	OSAP	NNP
cord-310847-63gh2tg4	907	14	)	)	-RRB-
cord-310847-63gh2tg4	907	15	is	be	VBZ
cord-310847-63gh2tg4	907	16	highly	highly	RB
cord-310847-63gh2tg4	907	17	expressed	express	VBN
cord-310847-63gh2tg4	907	18	in	in	IN
cord-310847-63gh2tg4	907	19	retina	retina	NN
cord-310847-63gh2tg4	907	20	that	that	WDT
cord-310847-63gh2tg4	907	21	exhibits	exhibit	VBZ
cord-310847-63gh2tg4	907	22	a	a	DT
cord-310847-63gh2tg4	907	23	large	large	JJ
cord-310847-63gh2tg4	907	24	area	area	NN
cord-310847-63gh2tg4	907	25	of	of	IN
cord-310847-63gh2tg4	907	26	intrinsic	intrinsic	JJ
cord-310847-63gh2tg4	907	27	disorder	disorder	NN
cord-310847-63gh2tg4	908	1	The	the	DT
cord-310847-63gh2tg4	908	2	expression	expression	NN
cord-310847-63gh2tg4	908	3	of	of	IN
cord-310847-63gh2tg4	908	4	a	a	DT
cord-310847-63gh2tg4	908	5	mitochondria	mitochondria	NN
cord-310847-63gh2tg4	908	6	-	-	HYPH
cord-310847-63gh2tg4	908	7	localized	localize	VBN
cord-310847-63gh2tg4	908	8	glutamic	glutamic	NN
cord-310847-63gh2tg4	908	9	acid	acid	NN
cord-310847-63gh2tg4	908	10	-	-	HYPH
cord-310847-63gh2tg4	908	11	rich	rich	JJ
cord-310847-63gh2tg4	908	12	protein	protein	NN
cord-310847-63gh2tg4	908	13	(	(	-LRB-
cord-310847-63gh2tg4	908	14	MGARP	MGARP	NNP
cord-310847-63gh2tg4	908	15	/	/	SYM
cord-310847-63gh2tg4	908	16	OSAP	OSAP	NNP
cord-310847-63gh2tg4	908	17	)	)	-RRB-
cord-310847-63gh2tg4	908	18	is	be	VBZ
cord-310847-63gh2tg4	908	19	under	under	IN
cord-310847-63gh2tg4	908	20	the	the	DT
cord-310847-63gh2tg4	908	21	regulation	regulation	NN
cord-310847-63gh2tg4	908	22	of	of	IN
cord-310847-63gh2tg4	908	23	the	the	DT
cord-310847-63gh2tg4	908	24	HPG	HPG	NNP
cord-310847-63gh2tg4	908	25	axis	axis	NN
cord-310847-63gh2tg4	908	26	Expression	expression	NN
cord-310847-63gh2tg4	908	27	of	of	IN
cord-310847-63gh2tg4	908	28	ovary	ovary	NN
cord-310847-63gh2tg4	908	29	-	-	HYPH
cord-310847-63gh2tg4	908	30	specific	specific	JJ
cord-310847-63gh2tg4	908	31	acidic	acidic	JJ
cord-310847-63gh2tg4	908	32	protein	protein	NN
cord-310847-63gh2tg4	908	33	in	in	IN
cord-310847-63gh2tg4	908	34	steroidogenic	steroidogenic	NNP
cord-310847-63gh2tg4	908	35	tissues	tissue	NNS
cord-310847-63gh2tg4	908	36	:	:	:
cord-310847-63gh2tg4	908	37	a	a	DT
cord-310847-63gh2tg4	908	38	possible	possible	JJ
cord-310847-63gh2tg4	908	39	role	role	NN
cord-310847-63gh2tg4	908	40	in	in	IN
cord-310847-63gh2tg4	908	41	steroidogenesis	steroidogenesis	NN
cord-310847-63gh2tg4	908	42	HUMMR	HUMMR	NNP
cord-310847-63gh2tg4	908	43	,	,	,
cord-310847-63gh2tg4	908	44	a	a	DT
cord-310847-63gh2tg4	908	45	hypoxia	hypoxia	NN
cord-310847-63gh2tg4	908	46	-	-	:
cord-310847-63gh2tg4	908	47	and	and	CC
cord-310847-63gh2tg4	908	48	HIF-1alpha	hif-1alpha	NN
cord-310847-63gh2tg4	908	49	-	-	HYPH
cord-310847-63gh2tg4	908	50	inducible	inducible	JJ
cord-310847-63gh2tg4	908	51	protein	protein	NN
cord-310847-63gh2tg4	908	52	,	,	,
cord-310847-63gh2tg4	908	53	alters	alter	VBZ
cord-310847-63gh2tg4	908	54	mitochondrial	mitochondrial	JJ
cord-310847-63gh2tg4	908	55	distribution	distribution	NN
cord-310847-63gh2tg4	908	56	and	and	CC
cord-310847-63gh2tg4	908	57	transport	transport	VB
cord-310847-63gh2tg4	908	58	A	a	DT
cord-310847-63gh2tg4	908	59	glutamic	glutamic	NN
cord-310847-63gh2tg4	908	60	acid	acid	NN
cord-310847-63gh2tg4	908	61	-	-	HYPH
cord-310847-63gh2tg4	908	62	rich	rich	JJ
cord-310847-63gh2tg4	908	63	protein	protein	NN
cord-310847-63gh2tg4	908	64	identified	identify	VBN
cord-310847-63gh2tg4	908	65	in	in	IN
cord-310847-63gh2tg4	908	66	Verticillium	Verticillium	NNP
cord-310847-63gh2tg4	908	67	dahliae	dahliae	NNS
cord-310847-63gh2tg4	908	68	from	from	IN
cord-310847-63gh2tg4	908	69	an	an	DT
cord-310847-63gh2tg4	908	70	insertional	insertional	JJ
cord-310847-63gh2tg4	908	71	mutagenesis	mutagenesis	NN
cord-310847-63gh2tg4	908	72	affects	affect	VBZ
cord-310847-63gh2tg4	908	73	microsclerotial	microsclerotial	JJ
cord-310847-63gh2tg4	908	74	formation	formation	NN
cord-310847-63gh2tg4	908	75	and	and	CC
cord-310847-63gh2tg4	908	76	pathogenicity	pathogenicity	NN
cord-310847-63gh2tg4	908	77	GALA	gala	NN
cord-310847-63gh2tg4	908	78	:	:	:
cord-310847-63gh2tg4	908	79	a	a	DT
cord-310847-63gh2tg4	908	80	designed	design	VBN
cord-310847-63gh2tg4	908	81	synthetic	synthetic	JJ
cord-310847-63gh2tg4	908	82	pH	ph	NN
cord-310847-63gh2tg4	908	83	-	-	HYPH
cord-310847-63gh2tg4	908	84	responsive	responsive	JJ
cord-310847-63gh2tg4	908	85	amphipathic	amphipathic	NNP
cord-310847-63gh2tg4	908	86	peptide	peptide	NN
cord-310847-63gh2tg4	908	87	with	with	IN
cord-310847-63gh2tg4	908	88	applications	application	NNS
cord-310847-63gh2tg4	908	89	in	in	IN
cord-310847-63gh2tg4	908	90	drug	drug	NN
cord-310847-63gh2tg4	908	91	and	and	CC
cord-310847-63gh2tg4	908	92	gene	gene	NN
cord-310847-63gh2tg4	908	93	delivery	delivery	NN
cord-310847-63gh2tg4	908	94	PEST	PEST	NNP
cord-310847-63gh2tg4	908	95	family	family	NN
cord-310847-63gh2tg4	908	96	phosphatases	phosphatase	VBZ
cord-310847-63gh2tg4	908	97	in	in	IN
cord-310847-63gh2tg4	908	98	immunity	immunity	NN
cord-310847-63gh2tg4	908	99	,	,	,
cord-310847-63gh2tg4	908	100	autoimmunity	autoimmunity	NN
cord-310847-63gh2tg4	908	101	,	,	,
cord-310847-63gh2tg4	908	102	and	and	CC
cord-310847-63gh2tg4	908	103	autoinflammatory	autoinflammatory	JJ
cord-310847-63gh2tg4	908	104	disorders	disorder	NNS
cord-310847-63gh2tg4	908	105	Regulation	Regulation	NNP
cord-310847-63gh2tg4	908	106	of	of	IN
cord-310847-63gh2tg4	908	107	tumor	tumor	NN
cord-310847-63gh2tg4	908	108	cell	cell	NN
cord-310847-63gh2tg4	908	109	migration	migration	NN
cord-310847-63gh2tg4	908	110	by	by	IN
cord-310847-63gh2tg4	908	111	protein	protein	NN
cord-310847-63gh2tg4	908	112	tyrosine	tyrosine	NN
cord-310847-63gh2tg4	908	113	phosphatase	phosphatase	NN
cord-310847-63gh2tg4	908	114	(	(	-LRB-
cord-310847-63gh2tg4	908	115	PTP)-proline-	ptp)-proline-	JJ
cord-310847-63gh2tg4	908	116	,	,	,
cord-310847-63gh2tg4	908	117	glutamate-	glutamate-	NNS
cord-310847-63gh2tg4	908	118	,	,	,
cord-310847-63gh2tg4	908	119	serine-	serine-	JJ
cord-310847-63gh2tg4	908	120	,	,	,
cord-310847-63gh2tg4	908	121	and	and	CC
cord-310847-63gh2tg4	908	122	threonine	threonine	JJ
cord-310847-63gh2tg4	908	123	-	-	HYPH
cord-310847-63gh2tg4	908	124	rich	rich	JJ
cord-310847-63gh2tg4	908	125	sequence	sequence	NN
cord-310847-63gh2tg4	909	1	(	(	-LRB-
cord-310847-63gh2tg4	909	2	PEST	PEST	NNP
cord-310847-63gh2tg4	909	3	)	)	-RRB-
cord-310847-63gh2tg4	910	1	Structural	structural	JJ
cord-310847-63gh2tg4	910	2	analysis	analysis	NN
cord-310847-63gh2tg4	910	3	of	of	IN
cord-310847-63gh2tg4	910	4	the	the	DT
cord-310847-63gh2tg4	910	5	Bacillus	Bacillus	NNP
cord-310847-63gh2tg4	910	6	subtilis	subtili	NNS
cord-310847-63gh2tg4	910	7	delta	delta	NN
cord-310847-63gh2tg4	910	8	factor	factor	NN
cord-310847-63gh2tg4	910	9	:	:	:
cord-310847-63gh2tg4	910	10	a	a	DT
cord-310847-63gh2tg4	910	11	protein	protein	NN
cord-310847-63gh2tg4	910	12	polyanion	polyanion	NN
cord-310847-63gh2tg4	910	13	which	which	WDT
cord-310847-63gh2tg4	910	14	displaces	displace	VBZ
cord-310847-63gh2tg4	910	15	RNA	RNA	NNP
cord-310847-63gh2tg4	910	16	from	from	IN
cord-310847-63gh2tg4	910	17	RNA	RNA	NNP
cord-310847-63gh2tg4	910	18	polymerase	polymerase	NN
cord-310847-63gh2tg4	910	19	MARCKS	MARCKS	NNP
cord-310847-63gh2tg4	910	20	:	:	:
cord-310847-63gh2tg4	910	21	a	a	DT
cord-310847-63gh2tg4	910	22	case	case	NN
cord-310847-63gh2tg4	910	23	of	of	IN
cord-310847-63gh2tg4	910	24	molecular	molecular	JJ
cord-310847-63gh2tg4	910	25	exaptation	exaptation	NN
cord-310847-63gh2tg4	910	26	?	?	.
cord-310847-63gh2tg4	911	1	Arginine	arginine	NN
cord-310847-63gh2tg4	911	2	and	and	CC
cord-310847-63gh2tg4	911	3	glutamate	glutamate	NN
cord-310847-63gh2tg4	911	4	-	-	HYPH
cord-310847-63gh2tg4	911	5	rich	rich	JJ
cord-310847-63gh2tg4	911	6	1	1	CD
cord-310847-63gh2tg4	911	7	(	(	-LRB-
cord-310847-63gh2tg4	911	8	ARGLU1	ARGLU1	NNP
cord-310847-63gh2tg4	911	9	)	)	-RRB-
cord-310847-63gh2tg4	911	10	interacts	interact	VBZ
cord-310847-63gh2tg4	911	11	with	with	IN
cord-310847-63gh2tg4	911	12	mediator	mediator	NN
cord-310847-63gh2tg4	911	13	subunit	subunit	NN
cord-310847-63gh2tg4	911	14	1	1	CD
cord-310847-63gh2tg4	911	15	(	(	-LRB-
cord-310847-63gh2tg4	911	16	MED1	MED1	NNP
cord-310847-63gh2tg4	911	17	)	)	-RRB-
cord-310847-63gh2tg4	911	18	and	and	CC
cord-310847-63gh2tg4	911	19	is	be	VBZ
cord-310847-63gh2tg4	911	20	required	require	VBN
cord-310847-63gh2tg4	911	21	for	for	IN
cord-310847-63gh2tg4	911	22	estrogen	estrogen	NN
cord-310847-63gh2tg4	911	23	receptor	receptor	NN
cord-310847-63gh2tg4	911	24	-	-	HYPH
cord-310847-63gh2tg4	911	25	mediated	mediate	VBN
cord-310847-63gh2tg4	911	26	gene	gene	NN
cord-310847-63gh2tg4	911	27	transcription	transcription	NN
cord-310847-63gh2tg4	911	28	and	and	CC
cord-310847-63gh2tg4	911	29	breast	breast	NN
cord-310847-63gh2tg4	911	30	cancer	cancer	NN
cord-310847-63gh2tg4	911	31	cell	cell	NN
cord-310847-63gh2tg4	911	32	growth	growth	NN
cord-310847-63gh2tg4	911	33	PELP1	pelp1	XX
cord-310847-63gh2tg4	911	34	-	-	HYPH
cord-310847-63gh2tg4	911	35	-a	-a	JJS
cord-310847-63gh2tg4	911	36	novel	novel	JJ
cord-310847-63gh2tg4	911	37	estrogen	estrogen	NN
cord-310847-63gh2tg4	911	38	receptorinteracting	receptorinteracte	VBG
cord-310847-63gh2tg4	911	39	protein	protein	NN
cord-310847-63gh2tg4	911	40	Growth	growth	NN
cord-310847-63gh2tg4	911	41	factor	factor	NN
cord-310847-63gh2tg4	911	42	regulation	regulation	NN
cord-310847-63gh2tg4	911	43	of	of	IN
cord-310847-63gh2tg4	911	44	estrogen	estrogen	NN
cord-310847-63gh2tg4	911	45	receptor	receptor	NN
cord-310847-63gh2tg4	911	46	coregulator	coregulator	NN
cord-310847-63gh2tg4	911	47	PELP1	PELP1	NNP
cord-310847-63gh2tg4	911	48	functions	function	NNS
cord-310847-63gh2tg4	911	49	via	via	IN
cord-310847-63gh2tg4	911	50	Protein	Protein	NNP
cord-310847-63gh2tg4	911	51	Kinase	Kinase	NNP
cord-310847-63gh2tg4	911	52	A	a	DT
cord-310847-63gh2tg4	911	53	pathway	pathway	NN
cord-310847-63gh2tg4	911	54	Functional	functional	JJ
cord-310847-63gh2tg4	911	55	significance	significance	NN
cord-310847-63gh2tg4	911	56	and	and	CC
cord-310847-63gh2tg4	911	57	mechanism	mechanism	NN
cord-310847-63gh2tg4	911	58	of	of	IN
cord-310847-63gh2tg4	911	59	eIF5-promoted	eif5-promoted	CD
cord-310847-63gh2tg4	911	60	GTP	gtp	NN
cord-310847-63gh2tg4	911	61	hydrolysis	hydrolysis	NN
cord-310847-63gh2tg4	911	62	in	in	IN
cord-310847-63gh2tg4	911	63	eukaryotic	eukaryotic	JJ
cord-310847-63gh2tg4	911	64	translation	translation	NN
cord-310847-63gh2tg4	911	65	initiation	initiation	NN
cord-310847-63gh2tg4	911	66	Interaction	Interaction	NNP
cord-310847-63gh2tg4	911	67	in	in	IN
cord-310847-63gh2tg4	911	68	vitro	vitro	FW
cord-310847-63gh2tg4	911	69	of	of	IN
cord-310847-63gh2tg4	911	70	non	non	JJ
cord-310847-63gh2tg4	911	71	-	-	JJ
cord-310847-63gh2tg4	911	72	epithelial	epithelial	JJ
cord-310847-63gh2tg4	911	73	intermediate	intermediate	JJ
cord-310847-63gh2tg4	911	74	filament	filament	NN
cord-310847-63gh2tg4	911	75	proteins	protein	NNS
cord-310847-63gh2tg4	911	76	with	with	IN
cord-310847-63gh2tg4	911	77	histones	histone	NNS
cord-310847-63gh2tg4	911	78	Isolation	isolation	NN
cord-310847-63gh2tg4	911	79	,	,	,
cord-310847-63gh2tg4	911	80	characterisation	characterisation	NN
cord-310847-63gh2tg4	911	81	and	and	CC
cord-310847-63gh2tg4	911	82	growth	growth	NN
cord-310847-63gh2tg4	911	83	-	-	HYPH
cord-310847-63gh2tg4	911	84	related	relate	VBN
cord-310847-63gh2tg4	911	85	changes	change	NNS
cord-310847-63gh2tg4	911	86	of	of	IN
cord-310847-63gh2tg4	911	87	an	an	DT
cord-310847-63gh2tg4	911	88	HMG	HMG	NNP
cord-310847-63gh2tg4	911	89	-	-	HYPH
cord-310847-63gh2tg4	911	90	like	like	JJ
cord-310847-63gh2tg4	911	91	protein	protein	NN
cord-310847-63gh2tg4	911	92	from	from	IN
cord-310847-63gh2tg4	911	93	microplasmodia	microplasmodia	NNS
cord-310847-63gh2tg4	911	94	of	of	IN
cord-310847-63gh2tg4	911	95	Physarum	Physarum	NNP
cord-310847-63gh2tg4	911	96	polycephalum	polycephalum	NN
cord-310847-63gh2tg4	911	97	Calcium	calcium	NN
cord-310847-63gh2tg4	911	98	-	-	HYPH
cord-310847-63gh2tg4	911	99	dependent	dependent	JJ
cord-310847-63gh2tg4	911	100	molecular	molecular	JJ
cord-310847-63gh2tg4	911	101	spring	spring	NN
cord-310847-63gh2tg4	911	102	elements	element	NNS
cord-310847-63gh2tg4	911	103	in	in	IN
cord-310847-63gh2tg4	911	104	the	the	DT
cord-310847-63gh2tg4	911	105	giant	giant	JJ
cord-310847-63gh2tg4	911	106	protein	protein	NN
cord-310847-63gh2tg4	911	107	titin	titin	NN
cord-310847-63gh2tg4	911	108	Isolation	Isolation	NNP
cord-310847-63gh2tg4	911	109	,	,	,
cord-310847-63gh2tg4	911	110	characterization	characterization	NN
cord-310847-63gh2tg4	911	111	,	,	,
cord-310847-63gh2tg4	911	112	and	and	CC
cord-310847-63gh2tg4	911	113	biosynthesis	biosynthesis	NN
cord-310847-63gh2tg4	911	114	of	of	IN
cord-310847-63gh2tg4	911	115	a	a	DT
cord-310847-63gh2tg4	911	116	phosphorylated	phosphorylated	JJ
cord-310847-63gh2tg4	911	117	glycoprotein	glycoprotein	NN
cord-310847-63gh2tg4	911	118	from	from	IN
cord-310847-63gh2tg4	911	119	rat	rat	NN
cord-310847-63gh2tg4	911	120	bone	bone	NN
cord-310847-63gh2tg4	911	121	Modulation	Modulation	NNP
cord-310847-63gh2tg4	911	122	of	of	IN
cord-310847-63gh2tg4	911	123	crystal	crystal	NN
cord-310847-63gh2tg4	911	124	formation	formation	NN
cord-310847-63gh2tg4	911	125	by	by	IN
cord-310847-63gh2tg4	911	126	bone	bone	NN
cord-310847-63gh2tg4	911	127	phosphoproteins	phosphoprotein	NNS
cord-310847-63gh2tg4	911	128	:	:	:
cord-310847-63gh2tg4	911	129	role	role	NN
cord-310847-63gh2tg4	911	130	of	of	IN
cord-310847-63gh2tg4	911	131	glutamic	glutamic	NN
cord-310847-63gh2tg4	911	132	acid	acid	NN
cord-310847-63gh2tg4	911	133	-	-	HYPH
cord-310847-63gh2tg4	911	134	rich	rich	JJ
cord-310847-63gh2tg4	911	135	sequences	sequence	NNS
cord-310847-63gh2tg4	911	136	in	in	IN
cord-310847-63gh2tg4	911	137	the	the	DT
cord-310847-63gh2tg4	911	138	nucleation	nucleation	NN
cord-310847-63gh2tg4	911	139	of	of	IN
cord-310847-63gh2tg4	911	140	hydroxyapatite	hydroxyapatite	NN
cord-310847-63gh2tg4	911	141	by	by	IN
cord-310847-63gh2tg4	911	142	bone	bone	NN
cord-310847-63gh2tg4	911	143	sialoprotein	sialoprotein	NNP
cord-310847-63gh2tg4	911	144	Acidic	acidic	JJ
cord-310847-63gh2tg4	911	145	amino	amino	NN
cord-310847-63gh2tg4	911	146	acid	acid	NN
cord-310847-63gh2tg4	911	147	-	-	HYPH
cord-310847-63gh2tg4	911	148	rich	rich	JJ
cord-310847-63gh2tg4	911	149	sequences	sequence	NNS
cord-310847-63gh2tg4	911	150	as	as	IN
cord-310847-63gh2tg4	911	151	binding	bind	VBG
cord-310847-63gh2tg4	911	152	sites	site	NNS
cord-310847-63gh2tg4	911	153	of	of	IN
cord-310847-63gh2tg4	911	154	osteonectin	osteonectin	NNS
cord-310847-63gh2tg4	911	155	to	to	IN
cord-310847-63gh2tg4	911	156	hydroxyapatite	hydroxyapatite	NN
cord-310847-63gh2tg4	911	157	crystals	crystal	NNS
cord-310847-63gh2tg4	912	1	Molecular	molecular	JJ
cord-310847-63gh2tg4	912	2	analysis	analysis	NN
cord-310847-63gh2tg4	912	3	of	of	IN
cord-310847-63gh2tg4	912	4	Xenopus	Xenopus	NNP
cord-310847-63gh2tg4	912	5	laevis	laevi	NNS
cord-310847-63gh2tg4	912	6	SPARC	SPARC	NNP
cord-310847-63gh2tg4	912	7	(	(	-LRB-
cord-310847-63gh2tg4	912	8	Secreted	Secreted	NNP
cord-310847-63gh2tg4	912	9	Protein	Protein	NNP
cord-310847-63gh2tg4	912	10	,	,	,
cord-310847-63gh2tg4	912	11	Acidic	acidic	JJ
cord-310847-63gh2tg4	912	12	,	,	,
cord-310847-63gh2tg4	912	13	Rich	Rich	NNP
cord-310847-63gh2tg4	912	14	in	in	IN
cord-310847-63gh2tg4	912	15	Cysteine	Cysteine	NNP
cord-310847-63gh2tg4	912	16	)	)	-RRB-
cord-310847-63gh2tg4	912	17	.	.	.
cord-310847-63gh2tg4	913	1	A	a	DT
cord-310847-63gh2tg4	913	2	highly	highly	RB
cord-310847-63gh2tg4	913	3	conserved	conserved	JJ
cord-310847-63gh2tg4	913	4	acidic	acidic	JJ
cord-310847-63gh2tg4	913	5	calciumbinding	calciumbinde	VBG
cord-310847-63gh2tg4	913	6	extracellular	extracellular	JJ
cord-310847-63gh2tg4	913	7	-	-	HYPH
cord-310847-63gh2tg4	913	8	matrix	matrix	NN
cord-310847-63gh2tg4	913	9	protein	protein	NN
cord-310847-63gh2tg4	913	10	Pcp4l1	pcp4l1	ADD
cord-310847-63gh2tg4	913	11	contains	contain	VBZ
cord-310847-63gh2tg4	913	12	an	an	DT
cord-310847-63gh2tg4	913	13	autoinhibitory	autoinhibitory	JJ
cord-310847-63gh2tg4	913	14	element	element	NN
cord-310847-63gh2tg4	913	15	that	that	WDT
cord-310847-63gh2tg4	913	16	prevents	prevent	VBZ
cord-310847-63gh2tg4	913	17	its	-PRON-	PRP$
cord-310847-63gh2tg4	913	18	IQ	iq	NN
cord-310847-63gh2tg4	913	19	motif	motif	NN
cord-310847-63gh2tg4	913	20	from	from	IN
cord-310847-63gh2tg4	913	21	binding	bind	VBG
cord-310847-63gh2tg4	913	22	to	to	IN
cord-310847-63gh2tg4	913	23	calmodulin	calmodulin	NN
cord-310847-63gh2tg4	913	24	Genetic	genetic	JJ
cord-310847-63gh2tg4	913	25	susceptibility	susceptibility	NN
cord-310847-63gh2tg4	913	26	and	and	CC
cord-310847-63gh2tg4	913	27	immune	immune	NN
cord-310847-63gh2tg4	913	28	-	-	HYPH
cord-310847-63gh2tg4	913	29	mediated	mediate	VBN
cord-310847-63gh2tg4	913	30	destruction	destruction	NN
cord-310847-63gh2tg4	913	31	in	in	IN
cord-310847-63gh2tg4	913	32	berylliuminduced	berylliuminduce	VBN
cord-310847-63gh2tg4	913	33	disease	disease	NN
cord-310847-63gh2tg4	913	34	Crowding	Crowding	NNP
cord-310847-63gh2tg4	913	35	and	and	CC
cord-310847-63gh2tg4	913	36	the	the	DT
cord-310847-63gh2tg4	913	37	polymerization	polymerization	NN
cord-310847-63gh2tg4	913	38	of	of	IN
cord-310847-63gh2tg4	913	39	sickle	sickle	NN
cord-310847-63gh2tg4	913	40	hemoglobin	hemoglobin	NN
cord-310847-63gh2tg4	913	41	Retinitis	Retinitis	NNP
cord-310847-63gh2tg4	913	42	pigmentosa	pigmentosa	NN
cord-310847-63gh2tg4	913	43	RPGR	RPGR	NNP
cord-310847-63gh2tg4	913	44	mutation	mutation	NN
cord-310847-63gh2tg4	913	45	analysis	analysis	NN
cord-310847-63gh2tg4	913	46	and	and	CC
cord-310847-63gh2tg4	913	47	disease	disease	NN
cord-310847-63gh2tg4	913	48	:	:	:
cord-310847-63gh2tg4	914	1	an	an	DT
cord-310847-63gh2tg4	914	2	update	update	NN
cord-310847-63gh2tg4	914	3	Mutations	Mutations	NNPS
cord-310847-63gh2tg4	914	4	in	in	IN
cord-310847-63gh2tg4	914	5	CD2BP1	cd2bp1	NN
cord-310847-63gh2tg4	914	6	disrupt	disrupt	VBP
cord-310847-63gh2tg4	914	7	binding	bind	VBG
cord-310847-63gh2tg4	914	8	to	to	IN
cord-310847-63gh2tg4	914	9	PTP	PTP	NNP
cord-310847-63gh2tg4	914	10	PEST	PEST	NNP
cord-310847-63gh2tg4	914	11	and	and	CC
cord-310847-63gh2tg4	914	12	are	be	VBP
cord-310847-63gh2tg4	914	13	responsible	responsible	JJ
cord-310847-63gh2tg4	914	14	for	for	IN
cord-310847-63gh2tg4	914	15	PAPA	PAPA	NNP
cord-310847-63gh2tg4	914	16	syndrome	syndrome	NN
cord-310847-63gh2tg4	914	17	,	,	,
cord-310847-63gh2tg4	914	18	an	an	DT
cord-310847-63gh2tg4	914	19	autoinflammatory	autoinflammatory	JJ
cord-310847-63gh2tg4	914	20	disorder	disorder	NN
cord-310847-63gh2tg4	914	21	Pyrin	Pyrin	NNP
cord-310847-63gh2tg4	914	22	binds	bind	VBZ
cord-310847-63gh2tg4	914	23	the	the	DT
cord-310847-63gh2tg4	914	24	PSTPIP1/	pstpip1/	JJ
cord-310847-63gh2tg4	914	25	CD2BP1	CD2BP1	NNP
cord-310847-63gh2tg4	914	26	protein	protein	NN
cord-310847-63gh2tg4	914	27	,	,	,
cord-310847-63gh2tg4	914	28	defining	define	VBG
cord-310847-63gh2tg4	914	29	familial	familial	JJ
cord-310847-63gh2tg4	914	30	Mediterranean	mediterranean	JJ
cord-310847-63gh2tg4	914	31	fever	fever	NN
cord-310847-63gh2tg4	914	32	and	and	CC
cord-310847-63gh2tg4	914	33	PAPA	PAPA	NNP
cord-310847-63gh2tg4	914	34	syndrome	syndrome	NN
cord-310847-63gh2tg4	914	35	as	as	IN
cord-310847-63gh2tg4	914	36	disorders	disorder	NNS
cord-310847-63gh2tg4	914	37	in	in	IN
cord-310847-63gh2tg4	914	38	the	the	DT
cord-310847-63gh2tg4	914	39	same	same	JJ
cord-310847-63gh2tg4	914	40	pathway	pathway	NN
cord-310847-63gh2tg4	914	41	Reduction	reduction	NN
cord-310847-63gh2tg4	914	42	in	in	IN
cord-310847-63gh2tg4	914	43	RNA	RNA	NNP
cord-310847-63gh2tg4	914	44	levels	level	NNS
cord-310847-63gh2tg4	914	45	rather	rather	RB
cord-310847-63gh2tg4	914	46	than	than	IN
cord-310847-63gh2tg4	914	47	retardation	retardation	NN
cord-310847-63gh2tg4	914	48	of	of	IN
cord-310847-63gh2tg4	914	49	translation	translation	NN
cord-310847-63gh2tg4	914	50	is	be	VBZ
cord-310847-63gh2tg4	914	51	responsible	responsible	JJ
cord-310847-63gh2tg4	914	52	for	for	IN
cord-310847-63gh2tg4	914	53	the	the	DT
cord-310847-63gh2tg4	914	54	inhibition	inhibition	NN
cord-310847-63gh2tg4	914	55	of	of	IN
cord-310847-63gh2tg4	914	56	major	major	JJ
cord-310847-63gh2tg4	914	57	histocompatibility	histocompatibility	NN
cord-310847-63gh2tg4	914	58	complex	complex	JJ
cord-310847-63gh2tg4	914	59	class	class	NN
cord-310847-63gh2tg4	914	60	I	-PRON-	PRP
cord-310847-63gh2tg4	914	61	antigen	antigen	NN
cord-310847-63gh2tg4	914	62	presentation	presentation	NN
cord-310847-63gh2tg4	914	63	by	by	IN
cord-310847-63gh2tg4	914	64	the	the	DT
cord-310847-63gh2tg4	914	65	glutamic	glutamic	NN
cord-310847-63gh2tg4	914	66	acid	acid	NN
cord-310847-63gh2tg4	914	67	-	-	HYPH
cord-310847-63gh2tg4	914	68	rich	rich	JJ
cord-310847-63gh2tg4	914	69	repeat	repeat	NN
cord-310847-63gh2tg4	914	70	of	of	IN
cord-310847-63gh2tg4	914	71	herpesvirus	herpesvirus	NNP
cord-310847-63gh2tg4	914	72	saimiri	saimiri	NNP
cord-310847-63gh2tg4	914	73	open	open	NNP
cord-310847-63gh2tg4	914	74	reading	reading	NN
cord-310847-63gh2tg4	914	75	frame	frame	NN
cord-310847-63gh2tg4	914	76	73	73	CD
cord-310847-63gh2tg4	914	77	Nuclear	nuclear	JJ
cord-310847-63gh2tg4	914	78	magnetic	magnetic	JJ
cord-310847-63gh2tg4	914	79	resonance	resonance	NN
cord-310847-63gh2tg4	914	80	structure	structure	NN
cord-310847-63gh2tg4	914	81	of	of	IN
cord-310847-63gh2tg4	914	82	the	the	DT
cord-310847-63gh2tg4	914	83	N	n	CD
cord-310847-63gh2tg4	914	84	-	-	HYPH
cord-310847-63gh2tg4	914	85	terminal	terminal	NN
cord-310847-63gh2tg4	914	86	domain	domain	NN
cord-310847-63gh2tg4	914	87	of	of	IN
cord-310847-63gh2tg4	914	88	nonstructural	nonstructural	JJ
cord-310847-63gh2tg4	914	89	protein	protein	NN
cord-310847-63gh2tg4	914	90	3	3	CD
cord-310847-63gh2tg4	914	91	from	from	IN
cord-310847-63gh2tg4	914	92	the	the	DT
cord-310847-63gh2tg4	914	93	severe	severe	JJ
cord-310847-63gh2tg4	914	94	acute	acute	JJ
cord-310847-63gh2tg4	914	95	respiratory	respiratory	JJ
cord-310847-63gh2tg4	914	96	syndrome	syndrome	NN
cord-310847-63gh2tg4	914	97	coronavirus	coronavirus	NN
cord-310847-63gh2tg4	914	98	Expression	expression	NN
cord-310847-63gh2tg4	914	99	of	of	IN
cord-310847-63gh2tg4	914	100	a	a	DT
cord-310847-63gh2tg4	914	101	Gene	Gene	NNP
cord-310847-63gh2tg4	914	102	Encoding	Encoding	NNP
cord-310847-63gh2tg4	914	103	34.9?kDa	34.9?kda	CD
cord-310847-63gh2tg4	914	104	PPE	PPE	NNP
cord-310847-63gh2tg4	914	105	Antigen	Antigen	NNP
cord-310847-63gh2tg4	914	106	of	of	IN
cord-310847-63gh2tg4	914	107	Mycobacterium	Mycobacterium	NNP
cord-310847-63gh2tg4	914	108	avium	avium	NN
cord-310847-63gh2tg4	914	109	subsp	subsp	NN
cord-310847-63gh2tg4	914	110	Isolation	isolation	NN
cord-310847-63gh2tg4	914	111	and	and	CC
cord-310847-63gh2tg4	914	112	characterization	characterization	NN
cord-310847-63gh2tg4	914	113	of	of	IN
cord-310847-63gh2tg4	914	114	the	the	DT
cord-310847-63gh2tg4	914	115	promoter	promoter	NN
cord-310847-63gh2tg4	914	116	sequence	sequence	NN
cord-310847-63gh2tg4	914	117	of	of	IN
cord-310847-63gh2tg4	914	118	a	a	DT
cord-310847-63gh2tg4	914	119	cassava	cassava	NN
cord-310847-63gh2tg4	914	120	gene	gene	NN
cord-310847-63gh2tg4	914	121	coding	code	VBG
cord-310847-63gh2tg4	914	122	for	for	IN
cord-310847-63gh2tg4	914	123	Pt2L4	Pt2L4	NNP
cord-310847-63gh2tg4	914	124	,	,	,
cord-310847-63gh2tg4	914	125	a	a	DT
cord-310847-63gh2tg4	914	126	glutamic	glutamic	NN
cord-310847-63gh2tg4	914	127	acid	acid	NN
cord-310847-63gh2tg4	914	128	-	-	HYPH
cord-310847-63gh2tg4	914	129	rich	rich	JJ
cord-310847-63gh2tg4	914	130	protein	protein	NN
cord-310847-63gh2tg4	914	131	differentially	differentially	RB
cord-310847-63gh2tg4	914	132	expressed	express	VBN
cord-310847-63gh2tg4	914	133	in	in	IN
cord-310847-63gh2tg4	914	134	storage	storage	NN
cord-310847-63gh2tg4	914	135	roots	root	NNS
cord-310847-63gh2tg4	914	136	iTRAQ	itraq	RB
cord-310847-63gh2tg4	914	137	-	-	HYPH
cord-310847-63gh2tg4	914	138	based	base	VBN
cord-310847-63gh2tg4	914	139	analysis	analysis	NN
cord-310847-63gh2tg4	914	140	of	of	IN
cord-310847-63gh2tg4	914	141	changes	change	NNS
cord-310847-63gh2tg4	914	142	in	in	IN
cord-310847-63gh2tg4	914	143	the	the	DT
cord-310847-63gh2tg4	914	144	cassava	cassava	NN
cord-310847-63gh2tg4	914	145	root	root	NN
cord-310847-63gh2tg4	914	146	proteome	proteome	NN
cord-310847-63gh2tg4	914	147	reveals	reveal	VBZ
cord-310847-63gh2tg4	914	148	pathways	pathway	NNS
cord-310847-63gh2tg4	914	149	associated	associate	VBN
cord-310847-63gh2tg4	914	150	with	with	IN
cord-310847-63gh2tg4	914	151	post	post	JJ
cord-310847-63gh2tg4	914	152	-	-	JJ
cord-310847-63gh2tg4	914	153	harvest	harvest	JJ
cord-310847-63gh2tg4	914	154	physiological	physiological	JJ
cord-310847-63gh2tg4	914	155	deterioration	deterioration	NN
cord-310847-63gh2tg4	914	156	The	the	DT
cord-310847-63gh2tg4	914	157	chromosomal	chromosomal	JJ
cord-310847-63gh2tg4	914	158	association	association	NN
cord-310847-63gh2tg4	914	159	/	/	SYM
cord-310847-63gh2tg4	914	160	dissociation	dissociation	NN
cord-310847-63gh2tg4	914	161	of	of	IN
cord-310847-63gh2tg4	914	162	the	the	DT
cord-310847-63gh2tg4	914	163	chromatin	chromatin	NN
cord-310847-63gh2tg4	914	164	insulator	insulator	NN
cord-310847-63gh2tg4	914	165	protein	protein	NN
cord-310847-63gh2tg4	914	166	Cp190	cp190	NN
cord-310847-63gh2tg4	914	167	of	of	IN
cord-310847-63gh2tg4	914	168	Drosophila	Drosophila	NNP
cord-310847-63gh2tg4	914	169	melanogaster	melanogaster	NN
cord-310847-63gh2tg4	914	170	is	be	VBZ
cord-310847-63gh2tg4	914	171	mediated	mediate	VBN
cord-310847-63gh2tg4	914	172	by	by	IN
cord-310847-63gh2tg4	914	173	the	the	DT
cord-310847-63gh2tg4	914	174	BTB	BTB	NNP
cord-310847-63gh2tg4	914	175	/	/	SYM
cord-310847-63gh2tg4	914	176	POZ	POZ	NNP
cord-310847-63gh2tg4	914	177	domain	domain	NN
cord-310847-63gh2tg4	914	178	and	and	CC
cord-310847-63gh2tg4	914	179	two	two	CD
cord-310847-63gh2tg4	914	180	acidic	acidic	JJ
cord-310847-63gh2tg4	914	181	regions	region	NNS
cord-310847-63gh2tg4	914	182	Proteomic	Proteomic	NNP
cord-310847-63gh2tg4	914	183	analysis	analysis	NN
cord-310847-63gh2tg4	914	184	of	of	IN
cord-310847-63gh2tg4	914	185	the	the	DT
cord-310847-63gh2tg4	914	186	brain	brain	NN
cord-310847-63gh2tg4	914	187	tissues	tissue	NNS
cord-310847-63gh2tg4	914	188	from	from	IN
cord-310847-63gh2tg4	914	189	a	a	DT
cord-310847-63gh2tg4	914	190	transgenic	transgenic	JJ
cord-310847-63gh2tg4	914	191	mouse	mouse	NN
cord-310847-63gh2tg4	914	192	model	model	NN
cord-310847-63gh2tg4	914	193	of	of	IN
cord-310847-63gh2tg4	914	194	amyloid	amyloid	NN
cord-310847-63gh2tg4	914	195	β	β	NNP
cord-310847-63gh2tg4	914	196	oligomers	oligomer	VBZ
cord-310847-63gh2tg4	914	197	Amino	Amino	NNP
cord-310847-63gh2tg4	914	198	terminus	terminus	NN
cord-310847-63gh2tg4	914	199	of	of	IN
cord-310847-63gh2tg4	914	200	Plasmodium	Plasmodium	NNP
cord-310847-63gh2tg4	914	201	falciparum	falciparum	NNS
cord-310847-63gh2tg4	914	202	acidic	acidic	JJ
cord-310847-63gh2tg4	914	203	basic	basic	JJ
cord-310847-63gh2tg4	914	204	repeat	repeat	NN
cord-310847-63gh2tg4	914	205	antigen	antigen	NN
cord-310847-63gh2tg4	914	206	interacts	interact	VBZ
cord-310847-63gh2tg4	914	207	with	with	IN
cord-310847-63gh2tg4	914	208	the	the	DT
cord-310847-63gh2tg4	914	209	erythrocyte	erythrocyte	NN
cord-310847-63gh2tg4	914	210	membrane	membrane	NN
cord-310847-63gh2tg4	914	211	through	through	IN
cord-310847-63gh2tg4	914	212	band	band	NN
cord-310847-63gh2tg4	914	213	3	3	CD
cord-310847-63gh2tg4	914	214	protein	protein	NN
cord-310847-63gh2tg4	914	215	Immunogenicity	Immunogenicity	NNP
cord-310847-63gh2tg4	914	216	of	of	IN
cord-310847-63gh2tg4	914	217	recombinant	recombinant	JJ
cord-310847-63gh2tg4	914	218	fragments	fragment	NNS
cord-310847-63gh2tg4	914	219	of	of	IN
cord-310847-63gh2tg4	914	220	Plasmodium	plasmodium	NN
cord-310847-63gh2tg4	914	221	falciparum	falciparum	NNS
cord-310847-63gh2tg4	914	222	acidic	acidic	JJ
cord-310847-63gh2tg4	914	223	basic	basic	JJ
cord-310847-63gh2tg4	914	224	repeat	repeat	NN
cord-310847-63gh2tg4	914	225	antigen	antigen	NN
cord-310847-63gh2tg4	914	226	produced	produce	VBN
cord-310847-63gh2tg4	914	227	in	in	IN
cord-310847-63gh2tg4	914	228	Escherichia	Escherichia	NNP
cord-310847-63gh2tg4	914	229	coli	coli	VBZ
cord-310847-63gh2tg4	914	230	Plasmodium	plasmodium	NN
cord-310847-63gh2tg4	914	231	falciparum	falciparum	NNS
cord-310847-63gh2tg4	914	232	:	:	:
cord-310847-63gh2tg4	914	233	chymotryptic	chymotryptic	JJ
cord-310847-63gh2tg4	914	234	-	-	HYPH
cord-310847-63gh2tg4	914	235	like	like	JJ
cord-310847-63gh2tg4	914	236	proteolysis	proteolysis	NN
cord-310847-63gh2tg4	914	237	associated	associate	VBN
cord-310847-63gh2tg4	914	238	with	with	IN
cord-310847-63gh2tg4	914	239	a	a	DT
cord-310847-63gh2tg4	914	240	101-kDa	101-kda	CD
cord-310847-63gh2tg4	914	241	acidic	acidic	JJ
cord-310847-63gh2tg4	914	242	-	-	HYPH
cord-310847-63gh2tg4	914	243	basic	basic	JJ
cord-310847-63gh2tg4	914	244	repeat	repeat	NN
cord-310847-63gh2tg4	914	245	antigen	antigen	NN
cord-310847-63gh2tg4	914	246	Expression	expression	NN
cord-310847-63gh2tg4	914	247	and	and	CC
cord-310847-63gh2tg4	914	248	characterisation	characterisation	NN
cord-310847-63gh2tg4	914	249	of	of	IN
cord-310847-63gh2tg4	914	250	Plasmodium	Plasmodium	NNP
cord-310847-63gh2tg4	914	251	falciparum	falciparum	NNS
cord-310847-63gh2tg4	914	252	acidic	acidic	JJ
cord-310847-63gh2tg4	914	253	basic	basic	JJ
cord-310847-63gh2tg4	914	254	repeat	repeat	NN
cord-310847-63gh2tg4	914	255	antigen	antigen	NN
cord-310847-63gh2tg4	914	256	expressed	express	VBN
cord-310847-63gh2tg4	914	257	in	in	IN
cord-310847-63gh2tg4	914	258	Escherichia	Escherichia	NNP
cord-310847-63gh2tg4	914	259	coli	coli	NNS
cord-310847-63gh2tg4	915	1	The	the	DT
cord-310847-63gh2tg4	915	2	lysine	lysine	NN
cord-310847-63gh2tg4	915	3	-	-	HYPH
cord-310847-63gh2tg4	915	4	and	and	CC
cord-310847-63gh2tg4	915	5	glutamic	glutamic	NN
cord-310847-63gh2tg4	915	6	acidrich	acidrich	NNP
cord-310847-63gh2tg4	915	7	protein	protein	NNP
cord-310847-63gh2tg4	915	8	KERP1	KERP1	NNP
cord-310847-63gh2tg4	915	9	plays	play	VBZ
cord-310847-63gh2tg4	915	10	a	a	DT
cord-310847-63gh2tg4	915	11	role	role	NN
cord-310847-63gh2tg4	915	12	in	in	IN
cord-310847-63gh2tg4	915	13	Entamoeba	Entamoeba	NNP
cord-310847-63gh2tg4	915	14	histolytica	histolytica	NNP
cord-310847-63gh2tg4	915	15	liver	liver	NN
cord-310847-63gh2tg4	915	16	abscess	abscess	NN
cord-310847-63gh2tg4	915	17	pathogenesis	pathogenesis	NN
cord-310847-63gh2tg4	916	1	The	the	DT
cord-310847-63gh2tg4	916	2	nested	nested	JJ
cord-310847-63gh2tg4	916	3	open	open	JJ
cord-310847-63gh2tg4	916	4	reading	reading	NN
cord-310847-63gh2tg4	916	5	frame	frame	NN
cord-310847-63gh2tg4	916	6	in	in	IN
cord-310847-63gh2tg4	916	7	the	the	DT
cord-310847-63gh2tg4	916	8	Epstein	Epstein	NNP
cord-310847-63gh2tg4	916	9	-	-	HYPH
cord-310847-63gh2tg4	916	10	Barr	Barr	NNP
cord-310847-63gh2tg4	916	11	virus	virus	NN
cord-310847-63gh2tg4	916	12	nuclear	nuclear	JJ
cord-310847-63gh2tg4	917	1	antigen-1	antigen-1	RB
cord-310847-63gh2tg4	918	1	mRNA	mRNA	NNP
cord-310847-63gh2tg4	918	2	encodes	encode	VBZ
cord-310847-63gh2tg4	918	3	a	a	DT
cord-310847-63gh2tg4	918	4	protein	protein	NN
cord-310847-63gh2tg4	918	5	capable	capable	JJ
cord-310847-63gh2tg4	918	6	of	of	IN
cord-310847-63gh2tg4	918	7	inhibiting	inhibit	VBG
cord-310847-63gh2tg4	918	8	antigen	antigen	NN
cord-310847-63gh2tg4	918	9	presentation	presentation	NN
cord-310847-63gh2tg4	918	10	in	in	IN
cord-310847-63gh2tg4	918	11	cis	cis	NNP