id author title date pages extension mime words sentences flesch summary cache txt cord-354465-5nqrrnqr Haslinger, Christian RNA structures with pseudo-knots: Graph-theoretical, combinatorial, and statistical properties 1999 .txt text/plain 10341 756 67 Numerical studies based on kinetic folding and a simple extension of the standard energy model show that the global features of the sequence-structure map of RNA do not change when pseudo-knots are introduced into the secondary structure picture. Numerical studies based on kinetic folding and a simple extension of the standard energy model show that the global features of the sequence-structure map of RNA do not change when pseudo-knots are introduced into the secondary structure picture. In case of one particular class of biopolymers, the ribonucleic acid (RNA) molecules, decoding of information stored in the sequence can be properly decomposed into two steps: (i) formation of the secondary structure, that is, of the pattern of Watson-Crick (and GU) base pairs, and (ii) the embedding of the contact structure in three-dimensional space. On the other hand, an increasing number of experimental findings, as well as results from comparative sequence analysis, suggest that pseudo-knots are important structural elements in many RNA molecules (Westhof and Jaeger, 1992) . ./cache/cord-354465-5nqrrnqr.txt ./txt/cord-354465-5nqrrnqr.txt