id author title date pages extension mime words sentences flesch summary cache txt cord-033010-o5kiadfm Durojaye, Olanrewaju Ayodeji Potential therapeutic target identification in the novel 2019 coronavirus: insight from homology modeling and blind docking study 2020-10-02 .txt text/plain 8125 375 53 RESULTS: This study describes the detailed computational process by which the 2019-nCoV main proteinase coding sequence was mapped out from the viral full genome, translated and the resultant amino acid sequence used in modeling the protein 3D structure. Our current study took advantage of the availability of the SARS CoV main proteinase amino acid sequence to map out the nucleotide coding region for the same protein in the 2019-nCoV. The predicted secondary structure composition shows a high degree of alpha helix and beta sheets, respectively, occupying 45 and 47% of the total residues with the percentage loop occupancy at 8% regarded as comparative modeling, constructs atomic models based on known structures or structures that have been determined experimentally and likewise share more than 40% sequence homology. ./cache/cord-033010-o5kiadfm.txt ./txt/cord-033010-o5kiadfm.txt