id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-023284-i0ecxgus	nan	Abstracts of publications related to QASR	2006-09-19		.txt	text/plain	19803	1320	48	Results: Methods developed for the investigation for the relationships between structure and toxic effects of compounds are summarized: a) The extra-thermodynamic approach: the Hansch paradigm, physical chemical properties that influence biological activity and their parametrization, originality of the Hansch approach, receptors and pharmacophores: the natural content of the Hansch approach, predictive value of QSARs, a statistifa1 tool: multiple linear regression analysis, the problem of correlations among molecular descriptors, other mathematical utilizations of extrathermodynamic parameters; b) The substructural approach: when topological (substructural) descriptors are needed, how to use topological decriptors; c) QSAR in mutagenicity and carcinogenicity: general problems, specific versions of the substructural approach used for mutagenicity and carcinogenicity, applications to mutagenicity and carcinogenicity.	./cache/cord-023284-i0ecxgus.txt	./txt/cord-023284-i0ecxgus.txt