id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-014685-ihh30q6f	nan	Posters P788 - P999	2005-09-21		.txt	text/plain	38354	1784	45	This study has attempted to analyse the structural properties of membrane peptides and proteins through the use of model systems that have been designed to mimic their natural counterparts: Podlubnaya 2 1 Institute of Theoretical and Experimental Biophysics RAS, 2 Pushchino State University Amyloid brils are formed by proteins or their peptides in the result of a conformational transition from alpha helix into beta-sheet structure. Analysis of the results of such studies indicate that folding of SNase fragments is dominated by developing the local and non-local nucleation sites from native-like secondary structures and by intensifying the longrange interactions of residues at nucleation sites with residues further removed in sequence. The results show that at different pH values the aggregation processes of both proteins follow different pathways determined by the variations in the native structure and by the details of the involved conformational changes.	./cache/cord-014685-ihh30q6f.txt	./txt/cord-014685-ihh30q6f.txt