id author title date pages extension mime words sentences flesch summary cache txt cord-003020-q69f57el Farhadi, Tayebeh Computer-aided design of amino acid-based therapeutics: a review 2018-05-14 .txt text/plain 8671 583 41 Computational techniques play a key role to design and develop the amino acid-based therapeutics such as proteins, peptides and peptidomimetics. Here, the elaborated techniques that are developed to characterize the amino acid sequences consistent with a specific structure and allow protein design are discussed. 3 Recently, pharmaceutical scientists have shown interest in engineering amino acid-based therapeutics such as proteins, peptides and peptidomimetics. Computer-aided design of amino acid-based therapeutics Fixing the backbone decreases the computational complication, but it may inhibit the main chain modifications to adjust sequence alternation. Computer-aided design of amino acid-based therapeutics to model peptide binding to targets of interest. 28, 134 Sequence-based method Recently, a method has been developed to rank peptide compound matches that are limited to short linear motifs in proteins and compounds with amino acid substituents. ./cache/cord-003020-q69f57el.txt ./txt/cord-003020-q69f57el.txt