id author title date pages extension mime words sentences flesch summary cache txt cord-317058-anvmj4li Liu, Xinkui Analysis of clinical features and early warning signs in patients with severe COVID-19: A retrospective cohort study 2020-06-26 .txt text/plain 3364 177 53 Multivariate logistic analysis indicated that patients aged ≥63 years (odds ratio = 41.0; 95% CI: 2.8, 592.4), with an absolute lymphocyte value of ≤1.02×10(9)/L (odds ratio = 6.1; 95% CI = 1.5, 25.2) and a C-reactive protein level of ≥65.08mg/L (odds ratio = 8.9; 95% CI = 1.0, 74.2) were at a higher risk of severe illness. Our study indicates that age, the absolute lymphocyte count at initial visit, and CRP may be used as predictors during the early stage of diagnosis in patients who are at risk of developing severe COVID-19. Although this study has some limitations, including a small sample size, few variables included in the multivariate analysis, a retrospective cohort design, and limited data collected from medical records, the results of our study indicate that older age, a decreased lymphocyte count on admission, and an increased concentration of serum CRP could serve as early warning signs in patients who are at risk of developing severe COVID-19. ./cache/cord-317058-anvmj4li.txt ./txt/cord-317058-anvmj4li.txt