id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-325985-xfzhn1n1	Jabado, Omar J.	Comprehensive viral oligonucleotide probe design using conserved protein regions	2007-12-13		.txt	text/plain	4260	227	47	The method uses the Protein Families database (Pfam) and motif finding algorithms to identify oligonucleotide probes in conserved amino acid regions and untranslated sequences. Our method for probe design employs protein alignment information, discovered protein motifs, nucleic acid motifs and finally, sliding windows to ensure near complete coverage of the database. The EMBL nucleotide sequence database [July 2007, Release 91; 461,353 nucleic acid sequences (31) ] was chosen as the reference for this study because it is tightly integrated with the Pfam protein family database (23, 32 Taxon growth was estimated using a standard least squares method, with the SPSS statistical package. We have described a method that capitalizes on the Pfam protein alignment database and a motif finding algorithm to automate the extraction of nucleic acid sequence for probes from conserved protein regions.	./cache/cord-325985-xfzhn1n1.txt	./txt/cord-325985-xfzhn1n1.txt