id author title date pages extension mime words sentences flesch summary cache txt cord-321715-bkfkmtld Redelings, Benjamin D Incorporating indel information into phylogeny estimation for rapidly emerging pathogens 2007-03-14 .txt text/plain 9793 546 54 To see if indel information improves phylogenetic resolution we compare the number of bi-partitions that are supported under the joint model and the traditional sequential approach, in which topology reconstruction assumes a previously determined alignment. These parameters include a multiple alignment A that specifies the positional homology between the sequences Y, an evolutionary tree (τ, T) where τ is an unrooted bifurcating tree topology and T = (t 1 , ..., t 2N -3 ) is a vector of branch lengths along the edges in τ, and vectors Θ and Λ are parameters that characterize the letter substitution and indel processes respectively. We therefore propose a new pairwise alignment prior that maintains a fixed sequence length distribution φ even when the indel probability varies from branch to branch. Since the joint model balances substitution and indel information as well as taking alignment ambiguity into account we assume that these differences represent an improvement in the accuracy of estimation. ./cache/cord-321715-bkfkmtld.txt ./txt/cord-321715-bkfkmtld.txt