id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-012975-u87ol3fs	Ogiwara, Atsushi	Construction of a dictionary of sequence motifs that characterize groups of related proteins	1992-09-17		.txt	text/plain	3112	165	55	An automatic procedure is proposed to identify, from the protein sequence database, conserved amino acid patterns (or sequence motifs) that are exclusive to a group of functionally related proteins. The conserved amino acid patterns, often called consensus patterns or sequence motifs (Taylor, 1988; Hodgman, 1989) , are usually identified by the tedious method of multiple aligning and comparing a group of functionally related sequences. This procedure is applied to the superfamily grouping of the PIR database and a library of sequence motifs is constructed that identifies specific superfamilies. Functional groups of proteins Suppose that a protein sequence database is divided into groups, each containing functionally related members, and that the diagnostic amino acid patterns that uniquely identify the membership to each functional group are required. Because the sequence motifs identified represent well conserved regions within a group of related proteins, they are likely to correspond to functionally important sites.	./cache/cord-012975-u87ol3fs.txt	./txt/cord-012975-u87ol3fs.txt