id	sid	tid	token	lemma	pos
cord-006460-3ayc0hne	1	1	key	key	JJ
cord-006460-3ayc0hne	1	2	:	:	:
cord-006460-3ayc0hne	1	3	cord-006460	cord-006460	NNP
cord-006460-3ayc0hne	1	4	-	-	HYPH
cord-006460-3ayc0hne	1	5	3ayc0hne	3ayc0hne	CD
cord-006460-3ayc0hne	1	6	authors	author	NNS
cord-006460-3ayc0hne	1	7	:	:	:
cord-006460-3ayc0hne	1	8	Baue	Baue	NNP
cord-006460-3ayc0hne	1	9	,	,	,
cord-006460-3ayc0hne	1	10	Arthur	Arthur	NNP
cord-006460-3ayc0hne	1	11	E.	E.	NNP
cord-006460-3ayc0hne	1	12	title	title	NN
cord-006460-3ayc0hne	1	13	:	:	:
cord-006460-3ayc0hne	1	14	Multiple	multiple	JJ
cord-006460-3ayc0hne	1	15	organ	organ	NN
cord-006460-3ayc0hne	1	16	failure	failure	NN
cord-006460-3ayc0hne	1	17	–	–	:
cord-006460-3ayc0hne	1	18	the	the	DT
cord-006460-3ayc0hne	1	19	discrepancy	discrepancy	NN
cord-006460-3ayc0hne	1	20	between	between	IN
cord-006460-3ayc0hne	1	21	our	-PRON-	PRP$
cord-006460-3ayc0hne	1	22	scientific	scientific	JJ
cord-006460-3ayc0hne	1	23	knowledge	knowledge	NN
cord-006460-3ayc0hne	1	24	and	and	CC
cord-006460-3ayc0hne	1	25	understanding	understanding	NN
cord-006460-3ayc0hne	1	26	and	and	CC
cord-006460-3ayc0hne	1	27	the	the	DT
cord-006460-3ayc0hne	1	28	management	management	NN
cord-006460-3ayc0hne	1	29	of	of	IN
cord-006460-3ayc0hne	1	30	our	-PRON-	PRP$
cord-006460-3ayc0hne	1	31	patients	patient	NNS
cord-006460-3ayc0hne	1	32	date	date	NN
cord-006460-3ayc0hne	1	33	:	:	:
cord-006460-3ayc0hne	1	34	2000	2000	CD
cord-006460-3ayc0hne	1	35	-	-	SYM
cord-006460-3ayc0hne	1	36	10	10	CD
cord-006460-3ayc0hne	1	37	-	-	SYM
cord-006460-3ayc0hne	1	38	19	19	CD
cord-006460-3ayc0hne	1	39	journal	journal	NN
cord-006460-3ayc0hne	1	40	:	:	:
cord-006460-3ayc0hne	2	1	Langenbecks	Langenbecks	NNP
cord-006460-3ayc0hne	2	2	Arch	Arch	NNP
cord-006460-3ayc0hne	2	3	Surg	Surg	NNP
cord-006460-3ayc0hne	2	4	DOI	doi	NN
cord-006460-3ayc0hne	2	5	:	:	:
cord-006460-3ayc0hne	2	6	10.1007	10.1007	CD
cord-006460-3ayc0hne	2	7	/	/	SYM
cord-006460-3ayc0hne	2	8	s004230000162	s004230000162	NN
cord-006460-3ayc0hne	2	9	sha	sha	NNP
cord-006460-3ayc0hne	2	10	:	:	:
cord-006460-3ayc0hne	2	11	6750d3e682b94b9c2eeda57c408245d1d680b0fb	6750d3e682b94b9c2eeda57c408245d1d680b0fb	CD
cord-006460-3ayc0hne	2	12	doc_id	doc_id	CD
cord-006460-3ayc0hne	2	13	:	:	:
cord-006460-3ayc0hne	3	1	6460	6460	CD
cord-006460-3ayc0hne	3	2	cord_uid	cord_uid	NNS
cord-006460-3ayc0hne	3	3	:	:	:
cord-006460-3ayc0hne	3	4	3ayc0hne	3ayc0hne	.
cord-006460-3ayc0hne	4	1	The	the	DT
cord-006460-3ayc0hne	4	2	excitement	excitement	NN
cord-006460-3ayc0hne	4	3	of	of	IN
cord-006460-3ayc0hne	4	4	molecular	molecular	JJ
cord-006460-3ayc0hne	4	5	biology	biology	NN
cord-006460-3ayc0hne	4	6	and	and	CC
cord-006460-3ayc0hne	4	7	of	of	IN
cord-006460-3ayc0hne	4	8	genetic	genetic	JJ
cord-006460-3ayc0hne	4	9	knowledge	knowledge	NN
cord-006460-3ayc0hne	4	10	and	and	CC
cord-006460-3ayc0hne	4	11	their	-PRON-	PRP$
cord-006460-3ayc0hne	4	12	possibilities	possibility	NNS
cord-006460-3ayc0hne	4	13	must	must	MD
cord-006460-3ayc0hne	4	14	be	be	VB
cord-006460-3ayc0hne	4	15	balanced	balance	VBN
cord-006460-3ayc0hne	4	16	against	against	IN
cord-006460-3ayc0hne	4	17	our	-PRON-	PRP$
cord-006460-3ayc0hne	4	18	limitations	limitation	NNS
cord-006460-3ayc0hne	4	19	in	in	IN
cord-006460-3ayc0hne	4	20	using	use	VBG
cord-006460-3ayc0hne	4	21	this	this	DT
cord-006460-3ayc0hne	4	22	information	information	NN
cord-006460-3ayc0hne	4	23	for	for	IN
cord-006460-3ayc0hne	4	24	the	the	DT
cord-006460-3ayc0hne	4	25	care	care	NN
cord-006460-3ayc0hne	4	26	of	of	IN
cord-006460-3ayc0hne	4	27	our	-PRON-	PRP$
cord-006460-3ayc0hne	4	28	patients	patient	NNS
cord-006460-3ayc0hne	4	29	.	.	.
cord-006460-3ayc0hne	5	1	There	there	EX
cord-006460-3ayc0hne	5	2	is	be	VBZ
cord-006460-3ayc0hne	5	3	a	a	DT
cord-006460-3ayc0hne	5	4	great	great	JJ
cord-006460-3ayc0hne	5	5	discrepancy	discrepancy	NN
cord-006460-3ayc0hne	5	6	between	between	IN
cord-006460-3ayc0hne	5	7	what	what	WP
cord-006460-3ayc0hne	5	8	we	-PRON-	PRP
cord-006460-3ayc0hne	5	9	know	know	VBP
cord-006460-3ayc0hne	5	10	and	and	CC
cord-006460-3ayc0hne	5	11	what	what	WP
cord-006460-3ayc0hne	5	12	we	-PRON-	PRP
cord-006460-3ayc0hne	5	13	can	can	MD
cord-006460-3ayc0hne	5	14	do	do	VB
cord-006460-3ayc0hne	5	15	.	.	.
cord-006460-3ayc0hne	6	1	There	there	EX
cord-006460-3ayc0hne	6	2	are	be	VBP
cord-006460-3ayc0hne	6	3	many	many	JJ
cord-006460-3ayc0hne	6	4	reasons	reason	NNS
cord-006460-3ayc0hne	6	5	for	for	IN
cord-006460-3ayc0hne	6	6	this	this	DT
cord-006460-3ayc0hne	6	7	.	.	.
cord-006460-3ayc0hne	7	1	A	a	DT
cord-006460-3ayc0hne	7	2	major	major	JJ
cord-006460-3ayc0hne	7	3	one	one	NN
cord-006460-3ayc0hne	7	4	is	be	VBZ
cord-006460-3ayc0hne	7	5	that	that	IN
cord-006460-3ayc0hne	7	6	science	science	NN
cord-006460-3ayc0hne	7	7	must	must	MD
cord-006460-3ayc0hne	7	8	simplify	simplify	VB
cord-006460-3ayc0hne	7	9	/	/	SYM
cord-006460-3ayc0hne	7	10	reduce	reduce	VB
cord-006460-3ayc0hne	7	11	the	the	DT
cord-006460-3ayc0hne	7	12	variables	variable	NNS
cord-006460-3ayc0hne	7	13	in	in	IN
cord-006460-3ayc0hne	7	14	experimentation	experimentation	NN
cord-006460-3ayc0hne	7	15	and	and	CC
cord-006460-3ayc0hne	7	16	then	then	RB
cord-006460-3ayc0hne	7	17	generalize	generalize	VB
cord-006460-3ayc0hne	7	18	in	in	IN
cord-006460-3ayc0hne	7	19	terms	term	NNS
cord-006460-3ayc0hne	7	20	of	of	IN
cord-006460-3ayc0hne	7	21	a	a	DT
cord-006460-3ayc0hne	7	22	specific	specific	JJ
cord-006460-3ayc0hne	7	23	factor	factor	NN
cord-006460-3ayc0hne	7	24	or	or	CC
cord-006460-3ayc0hne	7	25	effect	effect	NN
cord-006460-3ayc0hne	7	26	,	,	,
cord-006460-3ayc0hne	7	27	whereas	whereas	IN
cord-006460-3ayc0hne	7	28	patients	patient	NNS
cord-006460-3ayc0hne	7	29	are	be	VBP
cord-006460-3ayc0hne	7	30	complex	complex	JJ
cord-006460-3ayc0hne	7	31	with	with	IN
cord-006460-3ayc0hne	7	32	variables	variable	NNS
cord-006460-3ayc0hne	7	33	that	that	WDT
cord-006460-3ayc0hne	7	34	we	-PRON-	PRP
cord-006460-3ayc0hne	7	35	do	do	VBP
cord-006460-3ayc0hne	7	36	not	not	RB
cord-006460-3ayc0hne	7	37	yet	yet	RB
cord-006460-3ayc0hne	7	38	understand	understand	VB
cord-006460-3ayc0hne	7	39	completely	completely	RB
cord-006460-3ayc0hne	7	40	.	.	.
cord-006460-3ayc0hne	8	1	This	this	DT
cord-006460-3ayc0hne	8	2	powerful	powerful	JJ
cord-006460-3ayc0hne	8	3	science	science	NN
cord-006460-3ayc0hne	8	4	is	be	VBZ
cord-006460-3ayc0hne	8	5	now	now	RB
cord-006460-3ayc0hne	8	6	teaching	teach	VBG
cord-006460-3ayc0hne	8	7	us	-PRON-	PRP
cord-006460-3ayc0hne	8	8	about	about	IN
cord-006460-3ayc0hne	8	9	the	the	DT
cord-006460-3ayc0hne	8	10	genetic	genetic	JJ
cord-006460-3ayc0hne	8	11	diversity	diversity	NN
cord-006460-3ayc0hne	8	12	in	in	IN
cord-006460-3ayc0hne	8	13	both	both	DT
cord-006460-3ayc0hne	8	14	susceptibility	susceptibility	NN
cord-006460-3ayc0hne	8	15	and	and	CC
cord-006460-3ayc0hne	8	16	outcome	outcome	NN
cord-006460-3ayc0hne	8	17	of	of	IN
cord-006460-3ayc0hne	8	18	disease	disease	NN
cord-006460-3ayc0hne	8	19	,	,	,
cord-006460-3ayc0hne	8	20	and	and	CC
cord-006460-3ayc0hne	8	21	the	the	DT
cord-006460-3ayc0hne	8	22	diversity	diversity	NN
cord-006460-3ayc0hne	8	23	in	in	IN
cord-006460-3ayc0hne	8	24	life	life	NN
cord-006460-3ayc0hne	8	25	experiences	experience	NNS
cord-006460-3ayc0hne	8	26	and	and	CC
cord-006460-3ayc0hne	8	27	antigen	antigen	NN
cord-006460-3ayc0hne	8	28	exposures	exposure	NNS
cord-006460-3ayc0hne	8	29	.	.	.
cord-006460-3ayc0hne	9	1	Clinicians	clinician	NNS
cord-006460-3ayc0hne	9	2	have	have	VBP
cord-006460-3ayc0hne	9	3	tried	try	VBN
cord-006460-3ayc0hne	9	4	to	to	TO
cord-006460-3ayc0hne	9	5	lump	lump	VB
cord-006460-3ayc0hne	9	6	together	together	RB
cord-006460-3ayc0hne	9	7	and	and	CC
cord-006460-3ayc0hne	9	8	treat	treat	VB
cord-006460-3ayc0hne	9	9	in	in	IN
cord-006460-3ayc0hne	9	10	a	a	DT
cord-006460-3ayc0hne	9	11	similar	similar	JJ
cord-006460-3ayc0hne	9	12	way	way	NN
cord-006460-3ayc0hne	9	13	many	many	JJ
cord-006460-3ayc0hne	9	14	diverse	diverse	JJ
cord-006460-3ayc0hne	9	15	human	human	JJ
cord-006460-3ayc0hne	9	16	diseases	disease	NNS
cord-006460-3ayc0hne	9	17	.	.	.
cord-006460-3ayc0hne	10	1	This	this	DT
cord-006460-3ayc0hne	10	2	has	have	VBZ
cord-006460-3ayc0hne	10	3	not	not	RB
cord-006460-3ayc0hne	10	4	worked	work	VBN
cord-006460-3ayc0hne	10	5	well	well	RB
cord-006460-3ayc0hne	10	6	.	.	.
cord-006460-3ayc0hne	11	1	Pancreatitis	pancreatitis	NN
cord-006460-3ayc0hne	11	2	and	and	CC
cord-006460-3ayc0hne	11	3	perforated	perforated	JJ
cord-006460-3ayc0hne	11	4	diverticulitis	diverticulitis	NN
cord-006460-3ayc0hne	11	5	both	both	DT
cord-006460-3ayc0hne	11	6	produce	produce	VBP
cord-006460-3ayc0hne	11	7	inflammation	inflammation	NN
cord-006460-3ayc0hne	11	8	and	and	CC
cord-006460-3ayc0hne	11	9	sepsis	sepsis	NN
cord-006460-3ayc0hne	11	10	,	,	,
cord-006460-3ayc0hne	11	11	but	but	CC
cord-006460-3ayc0hne	11	12	they	-PRON-	PRP
cord-006460-3ayc0hne	11	13	are	be	VBP
cord-006460-3ayc0hne	11	14	different	different	JJ
cord-006460-3ayc0hne	11	15	processes	process	NNS
cord-006460-3ayc0hne	11	16	and	and	CC
cord-006460-3ayc0hne	11	17	may	may	MD
cord-006460-3ayc0hne	11	18	both	both	DT
cord-006460-3ayc0hne	11	19	lead	lead	VB
cord-006460-3ayc0hne	11	20	to	to	IN
cord-006460-3ayc0hne	11	21	multiple	multiple	JJ
cord-006460-3ayc0hne	11	22	organ	organ	NN
cord-006460-3ayc0hne	11	23	failure	failure	NN
cord-006460-3ayc0hne	11	24	.	.	.
cord-006460-3ayc0hne	12	1	This	this	DT
cord-006460-3ayc0hne	12	2	lumping	lump	VBG
cord-006460-3ayc0hne	12	3	together	together	RB
cord-006460-3ayc0hne	12	4	has	have	VBZ
cord-006460-3ayc0hne	12	5	contributed	contribute	VBN
cord-006460-3ayc0hne	12	6	to	to	IN
cord-006460-3ayc0hne	12	7	the	the	DT
cord-006460-3ayc0hne	12	8	failure	failure	NN
cord-006460-3ayc0hne	12	9	of	of	IN
cord-006460-3ayc0hne	12	10	so	so	RB
cord-006460-3ayc0hne	12	11	-	-	HYPH
cord-006460-3ayc0hne	12	12	called	call	VBN
cord-006460-3ayc0hne	12	13	magic	magic	JJ
cord-006460-3ayc0hne	12	14	bullets	bullet	NNS
cord-006460-3ayc0hne	12	15	.	.	.
cord-006460-3ayc0hne	13	1	There	there	EX
cord-006460-3ayc0hne	13	2	are	be	VBP
cord-006460-3ayc0hne	13	3	new	new	JJ
cord-006460-3ayc0hne	13	4	contributors	contributor	NNS
cord-006460-3ayc0hne	13	5	to	to	IN
cord-006460-3ayc0hne	13	6	organ	organ	NN
cord-006460-3ayc0hne	13	7	damage	damage	NN
cord-006460-3ayc0hne	13	8	.	.	.
cord-006460-3ayc0hne	14	1	Gender	gender	NN
cord-006460-3ayc0hne	14	2	,	,	,
cord-006460-3ayc0hne	14	3	lifestyle	lifestyle	NN
cord-006460-3ayc0hne	14	4	and	and	CC
cord-006460-3ayc0hne	14	5	prior	prior	JJ
cord-006460-3ayc0hne	14	6	disease	disease	NN
cord-006460-3ayc0hne	14	7	differences	difference	NNS
cord-006460-3ayc0hne	14	8	also	also	RB
cord-006460-3ayc0hne	14	9	complicate	complicate	VBP
cord-006460-3ayc0hne	14	10	the	the	DT
cord-006460-3ayc0hne	14	11	care	care	NN
cord-006460-3ayc0hne	14	12	of	of	IN
cord-006460-3ayc0hne	14	13	patients	patient	NNS
cord-006460-3ayc0hne	14	14	.	.	.
cord-006460-3ayc0hne	15	1	Despite	despite	IN
cord-006460-3ayc0hne	15	2	this	this	DT
cord-006460-3ayc0hne	15	3	,	,	,
cord-006460-3ayc0hne	15	4	we	-PRON-	PRP
cord-006460-3ayc0hne	15	5	are	be	VBP
cord-006460-3ayc0hne	15	6	slowly	slowly	RB
cord-006460-3ayc0hne	15	7	and	and	CC
cord-006460-3ayc0hne	15	8	gradually	gradually	RB
cord-006460-3ayc0hne	15	9	improving	improve	VBG
cord-006460-3ayc0hne	15	10	the	the	DT
cord-006460-3ayc0hne	15	11	care	care	NN
cord-006460-3ayc0hne	15	12	of	of	IN
cord-006460-3ayc0hne	15	13	our	-PRON-	PRP$
cord-006460-3ayc0hne	15	14	surgical	surgical	JJ
cord-006460-3ayc0hne	15	15	patients	patient	NNS
cord-006460-3ayc0hne	15	16	by	by	IN
cord-006460-3ayc0hne	15	17	careful	careful	JJ
cord-006460-3ayc0hne	15	18	pre-	pre-	NN
cord-006460-3ayc0hne	15	19	,	,	,
cord-006460-3ayc0hne	15	20	intra-	intra-	JJ
cord-006460-3ayc0hne	15	21	and	and	CC
cord-006460-3ayc0hne	15	22	postoperative	postoperative	JJ
cord-006460-3ayc0hne	15	23	support	support	NN
cord-006460-3ayc0hne	15	24	and	and	CC
cord-006460-3ayc0hne	15	25	better	well	JJR
cord-006460-3ayc0hne	15	26	,	,	,
cord-006460-3ayc0hne	15	27	simpler	simple	JJR
cord-006460-3ayc0hne	15	28	and	and	CC
cord-006460-3ayc0hne	15	29	safer	safe	JJR
cord-006460-3ayc0hne	15	30	operations	operation	NNS
cord-006460-3ayc0hne	15	31	.	.	.
cord-006460-3ayc0hne	16	1	There	there	EX
cord-006460-3ayc0hne	16	2	is	be	VBZ
cord-006460-3ayc0hne	16	3	a	a	DT
cord-006460-3ayc0hne	16	4	tremendous	tremendous	JJ
cord-006460-3ayc0hne	16	5	difference	difference	NN
cord-006460-3ayc0hne	16	6	between	between	IN
cord-006460-3ayc0hne	16	7	what	what	WP
cord-006460-3ayc0hne	16	8	we	-PRON-	PRP
cord-006460-3ayc0hne	16	9	know	know	VBP
cord-006460-3ayc0hne	16	10	in	in	IN
cord-006460-3ayc0hne	16	11	science	science	NN
cord-006460-3ayc0hne	16	12	and	and	CC
cord-006460-3ayc0hne	16	13	what	what	WP
cord-006460-3ayc0hne	16	14	we	-PRON-	PRP
cord-006460-3ayc0hne	16	15	can	can	MD
cord-006460-3ayc0hne	16	16	do	do	VB
cord-006460-3ayc0hne	16	17	for	for	IN
cord-006460-3ayc0hne	16	18	our	-PRON-	PRP$
cord-006460-3ayc0hne	16	19	patients	patient	NNS
cord-006460-3ayc0hne	16	20	.	.	.
cord-006460-3ayc0hne	17	1	The	the	DT
cord-006460-3ayc0hne	17	2	extraordinary	extraordinary	JJ
cord-006460-3ayc0hne	17	3	explosion	explosion	NN
cord-006460-3ayc0hne	17	4	of	of	IN
cord-006460-3ayc0hne	17	5	knowledge	knowledge	NN
cord-006460-3ayc0hne	17	6	about	about	IN
cord-006460-3ayc0hne	17	7	inflammation	inflammation	NN
cord-006460-3ayc0hne	17	8	,	,	,
cord-006460-3ayc0hne	17	9	mediators	mediator	NNS
cord-006460-3ayc0hne	17	10	and	and	CC
cord-006460-3ayc0hne	17	11	critically	critically	RB
cord-006460-3ayc0hne	17	12	ill	ill	JJ
cord-006460-3ayc0hne	17	13	patients	patient	NNS
cord-006460-3ayc0hne	17	14	has	have	VBZ
cord-006460-3ayc0hne	17	15	greatly	greatly	RB
cord-006460-3ayc0hne	17	16	increased	increase	VBN
cord-006460-3ayc0hne	17	17	our	-PRON-	PRP$
cord-006460-3ayc0hne	17	18	knowledge	knowledge	NN
cord-006460-3ayc0hne	17	19	of	of	IN
cord-006460-3ayc0hne	17	20	these	these	DT
cord-006460-3ayc0hne	17	21	processes	process	NNS
cord-006460-3ayc0hne	17	22	.	.	.
cord-006460-3ayc0hne	18	1	Therapy	therapy	NN
cord-006460-3ayc0hne	18	2	has	have	VBZ
cord-006460-3ayc0hne	18	3	improved	improve	VBN
cord-006460-3ayc0hne	18	4	,	,	,
cord-006460-3ayc0hne	18	5	but	but	CC
cord-006460-3ayc0hne	18	6	at	at	IN
cord-006460-3ayc0hne	18	7	a	a	DT
cord-006460-3ayc0hne	18	8	slower	slow	JJR
cord-006460-3ayc0hne	18	9	and	and	CC
cord-006460-3ayc0hne	18	10	more	more	RBR
cord-006460-3ayc0hne	18	11	gradual	gradual	JJ
cord-006460-3ayc0hne	18	12	pace	pace	NN
cord-006460-3ayc0hne	18	13	,	,	,
cord-006460-3ayc0hne	18	14	primarily	primarily	RB
cord-006460-3ayc0hne	18	15	by	by	IN
cord-006460-3ayc0hne	18	16	better	well	JJR
cord-006460-3ayc0hne	18	17	monitoring	monitoring	NN
cord-006460-3ayc0hne	18	18	and	and	CC
cord-006460-3ayc0hne	18	19	support	support	NN
cord-006460-3ayc0hne	18	20	of	of	IN
cord-006460-3ayc0hne	18	21	organ	organ	NN
cord-006460-3ayc0hne	18	22	function	function	NN
cord-006460-3ayc0hne	18	23	.	.	.
cord-006460-3ayc0hne	19	1	A	a	DT
cord-006460-3ayc0hne	19	2	classic	classic	JJ
cord-006460-3ayc0hne	19	3	example	example	NN
cord-006460-3ayc0hne	19	4	of	of	IN
cord-006460-3ayc0hne	19	5	this	this	DT
cord-006460-3ayc0hne	19	6	phenomenon	phenomenon	NN
cord-006460-3ayc0hne	19	7	is	be	VBZ
cord-006460-3ayc0hne	19	8	demonstrated	demonstrate	VBN
cord-006460-3ayc0hne	19	9	by	by	IN
cord-006460-3ayc0hne	19	10	the	the	DT
cord-006460-3ayc0hne	19	11	presentation	presentation	NN
cord-006460-3ayc0hne	19	12	of	of	IN
cord-006460-3ayc0hne	19	13	the	the	DT
cord-006460-3ayc0hne	19	14	1999	1999	CD
cord-006460-3ayc0hne	19	15	Nobel	Nobel	NNP
cord-006460-3ayc0hne	19	16	Prize	Prize	NNP
cord-006460-3ayc0hne	19	17	in	in	IN
cord-006460-3ayc0hne	19	18	Physiology	Physiology	NNP
cord-006460-3ayc0hne	19	19	and	and	CC
cord-006460-3ayc0hne	19	20	Medicine	Medicine	NNP
cord-006460-3ayc0hne	19	21	to	to	IN
cord-006460-3ayc0hne	19	22	Robert	Robert	NNP
cord-006460-3ayc0hne	19	23	Furchgott	Furchgott	NNP
cord-006460-3ayc0hne	19	24	,	,	,
cord-006460-3ayc0hne	19	25	Louis	Louis	NNP
cord-006460-3ayc0hne	19	26	Ignarro	Ignarro	NNP
cord-006460-3ayc0hne	19	27	and	and	CC
cord-006460-3ayc0hne	19	28	Ferid	Ferid	NNP
cord-006460-3ayc0hne	19	29	Murad	Murad	NNP
cord-006460-3ayc0hne	19	30	[	[	-LRB-
cord-006460-3ayc0hne	19	31	1	1	CD
cord-006460-3ayc0hne	19	32	]	]	-RRB-
cord-006460-3ayc0hne	19	33	.	.	.
cord-006460-3ayc0hne	20	1	These	these	DT
cord-006460-3ayc0hne	20	2	scientists	scientist	NNS
cord-006460-3ayc0hne	20	3	demonstrated	demonstrate	VBD
cord-006460-3ayc0hne	20	4	that	that	IN
cord-006460-3ayc0hne	20	5	vascular	vascular	JJ
cord-006460-3ayc0hne	20	6	endothelial	endothelial	JJ
cord-006460-3ayc0hne	20	7	cells	cell	NNS
cord-006460-3ayc0hne	20	8	form	form	VBP
cord-006460-3ayc0hne	20	9	nitric	nitric	NN
cord-006460-3ayc0hne	20	10	oxide	oxide	NN
cord-006460-3ayc0hne	20	11	(	(	-LRB-
cord-006460-3ayc0hne	20	12	NO	no	UH
cord-006460-3ayc0hne	20	13	)	)	-RRB-
cord-006460-3ayc0hne	20	14	through	through	IN
cord-006460-3ayc0hne	20	15	nitric	nitric	JJ
cord-006460-3ayc0hne	20	16	oxide	oxide	NN
cord-006460-3ayc0hne	20	17	synthase	synthase	NN
cord-006460-3ayc0hne	20	18	(	(	-LRB-
cord-006460-3ayc0hne	20	19	NOS	NOS	NNP
cord-006460-3ayc0hne	20	20	)	)	-RRB-
cord-006460-3ayc0hne	20	21	,	,	,
cord-006460-3ayc0hne	20	22	which	which	WDT
cord-006460-3ayc0hne	20	23	in	in	IN
cord-006460-3ayc0hne	20	24	turn	turn	NN
cord-006460-3ayc0hne	20	25	stimulates	stimulate	VBZ
cord-006460-3ayc0hne	20	26	cyclic	cyclic	JJ
cord-006460-3ayc0hne	20	27	guanosine	guanosine	NN
cord-006460-3ayc0hne	20	28	monophosphate	monophosphate	NN
cord-006460-3ayc0hne	20	29	(	(	-LRB-
cord-006460-3ayc0hne	20	30	cGMP	cGMP	NNP
cord-006460-3ayc0hne	20	31	)	)	-RRB-
cord-006460-3ayc0hne	20	32	synthesis	synthesis	NN
cord-006460-3ayc0hne	20	33	in	in	IN
cord-006460-3ayc0hne	20	34	the	the	DT
cord-006460-3ayc0hne	20	35	underlying	underlying	JJ
cord-006460-3ayc0hne	20	36	vascular	vascular	JJ
cord-006460-3ayc0hne	20	37	smooth	smooth	JJ
cord-006460-3ayc0hne	20	38	muscle	muscle	NN
cord-006460-3ayc0hne	20	39	causing	cause	VBG
cord-006460-3ayc0hne	20	40	relaxation	relaxation	NN
cord-006460-3ayc0hne	20	41	or	or	CC
cord-006460-3ayc0hne	20	42	vasodilatation	vasodilatation	NN
cord-006460-3ayc0hne	20	43	.	.	.
cord-006460-3ayc0hne	21	1	This	this	DT
cord-006460-3ayc0hne	21	2	exciting	exciting	JJ
cord-006460-3ayc0hne	21	3	contribution	contribution	NN
cord-006460-3ayc0hne	21	4	opened	open	VBD
cord-006460-3ayc0hne	21	5	up	up	RP
cord-006460-3ayc0hne	21	6	the	the	DT
cord-006460-3ayc0hne	21	7	entire	entire	JJ
cord-006460-3ayc0hne	21	8	world	world	NN
cord-006460-3ayc0hne	21	9	of	of	IN
cord-006460-3ayc0hne	21	10	NO	no	NN
cord-006460-3ayc0hne	21	11	and	and	CC
cord-006460-3ayc0hne	21	12	its	-PRON-	PRP$
cord-006460-3ayc0hne	21	13	many	many	JJ
cord-006460-3ayc0hne	21	14	biologic	biologic	JJ
cord-006460-3ayc0hne	21	15	functions	function	NNS
cord-006460-3ayc0hne	21	16	.	.	.
cord-006460-3ayc0hne	22	1	It	-PRON-	PRP
cord-006460-3ayc0hne	22	2	is	be	VBZ
cord-006460-3ayc0hne	22	3	an	an	DT
cord-006460-3ayc0hne	22	4	important	important	JJ
cord-006460-3ayc0hne	22	5	mechanism	mechanism	NN
cord-006460-3ayc0hne	22	6	whose	whose	WP$
cord-006460-3ayc0hne	22	7	activities	activity	NNS
cord-006460-3ayc0hne	22	8	are	be	VBP
cord-006460-3ayc0hne	22	9	still	still	RB
cord-006460-3ayc0hne	22	10	being	be	VBG
cord-006460-3ayc0hne	22	11	mapped	map	VBN
cord-006460-3ayc0hne	22	12	out	out	RP
cord-006460-3ayc0hne	22	13	.	.	.
cord-006460-3ayc0hne	23	1	This	this	DT
cord-006460-3ayc0hne	23	2	led	lead	VBD
cord-006460-3ayc0hne	23	3	to	to	IN
cord-006460-3ayc0hne	23	4	the	the	DT
cord-006460-3ayc0hne	23	5	study	study	NN
cord-006460-3ayc0hne	23	6	of	of	IN
cord-006460-3ayc0hne	23	7	excess	excess	JJ
cord-006460-3ayc0hne	23	8	vasodilatation	vasodilatation	NN
cord-006460-3ayc0hne	23	9	in	in	IN
cord-006460-3ayc0hne	23	10	septic	septic	JJ
cord-006460-3ayc0hne	23	11	shock	shock	NN
cord-006460-3ayc0hne	23	12	,	,	,
cord-006460-3ayc0hne	23	13	which	which	WDT
cord-006460-3ayc0hne	23	14	was	be	VBD
cord-006460-3ayc0hne	23	15	thought	think	VBN
cord-006460-3ayc0hne	23	16	to	to	TO
cord-006460-3ayc0hne	23	17	be	be	VB
cord-006460-3ayc0hne	23	18	due	due	JJ
cord-006460-3ayc0hne	23	19	to	to	IN
cord-006460-3ayc0hne	23	20	the	the	DT
cord-006460-3ayc0hne	23	21	overproduction	overproduction	NN
cord-006460-3ayc0hne	23	22	of	of	IN
cord-006460-3ayc0hne	23	23	NO	no	NN
cord-006460-3ayc0hne	23	24	.	.	.
cord-006460-3ayc0hne	24	1	Many	many	JJ
cord-006460-3ayc0hne	24	2	animal	animal	NN
cord-006460-3ayc0hne	24	3	and	and	CC
cord-006460-3ayc0hne	24	4	clinical	clinical	JJ
cord-006460-3ayc0hne	24	5	studies	study	NNS
cord-006460-3ayc0hne	24	6	suggested	suggest	VBD
cord-006460-3ayc0hne	24	7	that	that	IN
cord-006460-3ayc0hne	24	8	this	this	DT
cord-006460-3ayc0hne	24	9	phenomenon	phenomenon	NN
cord-006460-3ayc0hne	24	10	was	be	VBD
cord-006460-3ayc0hne	24	11	occurring	occur	VBG
cord-006460-3ayc0hne	24	12	.	.	.
cord-006460-3ayc0hne	25	1	It	-PRON-	PRP
cord-006460-3ayc0hne	25	2	was	be	VBD
cord-006460-3ayc0hne	25	3	then	then	RB
cord-006460-3ayc0hne	25	4	proposed	propose	VBN
cord-006460-3ayc0hne	25	5	that	that	IN
cord-006460-3ayc0hne	25	6	a	a	DT
cord-006460-3ayc0hne	25	7	NOS	NOS	NNP
cord-006460-3ayc0hne	25	8	inhibitor	inhibitor	NN
cord-006460-3ayc0hne	25	9	would	would	MD
cord-006460-3ayc0hne	25	10	help	help	VB
cord-006460-3ayc0hne	25	11	prevent	prevent	VB
cord-006460-3ayc0hne	25	12	this	this	DT
cord-006460-3ayc0hne	25	13	problem	problem	NN
cord-006460-3ayc0hne	25	14	of	of	IN
cord-006460-3ayc0hne	25	15	excess	excess	JJ
cord-006460-3ayc0hne	25	16	vasodilatation	vasodilatation	NN
cord-006460-3ayc0hne	25	17	and	and	CC
cord-006460-3ayc0hne	25	18	decreased	decrease	VBD
cord-006460-3ayc0hne	25	19	blood	blood	NN
cord-006460-3ayc0hne	25	20	flow	flow	NN
cord-006460-3ayc0hne	25	21	in	in	IN
cord-006460-3ayc0hne	25	22	septic	septic	JJ
cord-006460-3ayc0hne	25	23	shock	shock	NN
cord-006460-3ayc0hne	25	24	[	[	-LRB-
cord-006460-3ayc0hne	25	25	2	2	CD
cord-006460-3ayc0hne	25	26	,	,	,
cord-006460-3ayc0hne	25	27	3	3	CD
cord-006460-3ayc0hne	25	28	]	]	-RRB-
cord-006460-3ayc0hne	25	29	.	.	.
cord-006460-3ayc0hne	26	1	Many	many	JJ
cord-006460-3ayc0hne	26	2	trials	trial	NNS
cord-006460-3ayc0hne	26	3	and	and	CC
cord-006460-3ayc0hne	26	4	experiments	experiment	NNS
cord-006460-3ayc0hne	26	5	of	of	IN
cord-006460-3ayc0hne	26	6	NOS	NOS	NNP
cord-006460-3ayc0hne	26	7	inhibitors	inhibitor	NNS
cord-006460-3ayc0hne	26	8	were	be	VBD
cord-006460-3ayc0hne	26	9	performed	perform	VBN
cord-006460-3ayc0hne	26	10	in	in	IN
cord-006460-3ayc0hne	26	11	animals	animal	NNS
cord-006460-3ayc0hne	26	12	and	and	CC
cord-006460-3ayc0hne	26	13	patients	patient	NNS
cord-006460-3ayc0hne	26	14	.	.	.
cord-006460-3ayc0hne	27	1	However	however	RB
cord-006460-3ayc0hne	27	2	,	,	,
cord-006460-3ayc0hne	27	3	in	in	IN
cord-006460-3ayc0hne	27	4	a	a	DT
cord-006460-3ayc0hne	27	5	recent	recent	JJ
cord-006460-3ayc0hne	27	6	issue	issue	NN
cord-006460-3ayc0hne	27	7	of	of	IN
cord-006460-3ayc0hne	27	8	Critical	Critical	NNP
cord-006460-3ayc0hne	27	9	Care	Care	NNP
cord-006460-3ayc0hne	27	10	Medicine	Medicine	NNP
cord-006460-3ayc0hne	27	11	,	,	,
cord-006460-3ayc0hne	27	12	Grover	Grover	NNP
cord-006460-3ayc0hne	27	13	et	et	NNP
cord-006460-3ayc0hne	27	14	al	al	NNP
cord-006460-3ayc0hne	27	15	.	.	.
cord-006460-3ayc0hne	28	1	[	[	-LRB-
cord-006460-3ayc0hne	28	2	4	4	CD
cord-006460-3ayc0hne	28	3	]	]	-RRB-
cord-006460-3ayc0hne	28	4	reported	report	VBD
cord-006460-3ayc0hne	28	5	that	that	IN
cord-006460-3ayc0hne	28	6	the	the	DT
cord-006460-3ayc0hne	28	7	randomized	randomized	JJ
cord-006460-3ayc0hne	28	8	,	,	,
cord-006460-3ayc0hne	28	9	double	double	JJ
cord-006460-3ayc0hne	28	10	-	-	HYPH
cord-006460-3ayc0hne	28	11	blind	blind	JJ
cord-006460-3ayc0hne	28	12	clinical	clinical	JJ
cord-006460-3ayc0hne	28	13	trial	trial	NN
cord-006460-3ayc0hne	28	14	of	of	IN
cord-006460-3ayc0hne	28	15	an	an	DT
cord-006460-3ayc0hne	28	16	NOS	NOS	NNP
cord-006460-3ayc0hne	28	17	inhibitor	inhibitor	NN
cord-006460-3ayc0hne	28	18	was	be	VBD
cord-006460-3ayc0hne	28	19	discontinued	discontinue	VBN
cord-006460-3ayc0hne	28	20	due	due	IN
cord-006460-3ayc0hne	28	21	to	to	IN
cord-006460-3ayc0hne	28	22	increased	increase	VBN
cord-006460-3ayc0hne	28	23	mortality	mortality	NN
cord-006460-3ayc0hne	28	24	and	and	CC
cord-006460-3ayc0hne	28	25	adverse	adverse	JJ
cord-006460-3ayc0hne	28	26	outcomes	outcome	NNS
cord-006460-3ayc0hne	28	27	in	in	IN
cord-006460-3ayc0hne	28	28	patients	patient	NNS
cord-006460-3ayc0hne	28	29	who	who	WP
cord-006460-3ayc0hne	28	30	received	receive	VBD
cord-006460-3ayc0hne	28	31	the	the	DT
cord-006460-3ayc0hne	28	32	drug	drug	NN
cord-006460-3ayc0hne	28	33	.	.	.
cord-006460-3ayc0hne	29	1	There	there	EX
cord-006460-3ayc0hne	29	2	is	be	VBZ
cord-006460-3ayc0hne	29	3	now	now	RB
cord-006460-3ayc0hne	29	4	a	a	DT
cord-006460-3ayc0hne	29	5	moratorium	moratorium	NN
cord-006460-3ayc0hne	29	6	against	against	IN
cord-006460-3ayc0hne	29	7	the	the	DT
cord-006460-3ayc0hne	29	8	clinical	clinical	JJ
cord-006460-3ayc0hne	29	9	use	use	NN
cord-006460-3ayc0hne	29	10	of	of	IN
cord-006460-3ayc0hne	29	11	such	such	JJ
cord-006460-3ayc0hne	29	12	agents	agent	NNS
cord-006460-3ayc0hne	29	13	until	until	IN
cord-006460-3ayc0hne	29	14	more	more	JJR
cord-006460-3ayc0hne	29	15	is	be	VBZ
cord-006460-3ayc0hne	29	16	learned	learn	VBN
cord-006460-3ayc0hne	29	17	about	about	IN
cord-006460-3ayc0hne	29	18	them	-PRON-	PRP
cord-006460-3ayc0hne	29	19	.	.	.
cord-006460-3ayc0hne	30	1	Here	here	RB
cord-006460-3ayc0hne	30	2	,	,	,
cord-006460-3ayc0hne	30	3	then	then	RB
cord-006460-3ayc0hne	30	4	,	,	,
cord-006460-3ayc0hne	30	5	is	be	VBZ
cord-006460-3ayc0hne	30	6	an	an	DT
cord-006460-3ayc0hne	30	7	example	example	NN
cord-006460-3ayc0hne	30	8	of	of	IN
cord-006460-3ayc0hne	30	9	a	a	DT
cord-006460-3ayc0hne	30	10	Nobel	Nobel	NNP
cord-006460-3ayc0hne	30	11	Prize	Prize	NNP
cord-006460-3ayc0hne	30	12	being	be	VBG
cord-006460-3ayc0hne	30	13	awarded	award	VBN
cord-006460-3ayc0hne	30	14	for	for	IN
cord-006460-3ayc0hne	30	15	the	the	DT
cord-006460-3ayc0hne	30	16	study	study	NN
cord-006460-3ayc0hne	30	17	of	of	IN
cord-006460-3ayc0hne	30	18	endothelial	endothelial	JJ
cord-006460-3ayc0hne	30	19	A.E.	A.E.	NNP
cord-006460-3ayc0hne	30	20	Baue	Baue	NNP
cord-006460-3ayc0hne	30	21	(	(	-LRB-
cord-006460-3ayc0hne	30	22	✉	✉	JJ
cord-006460-3ayc0hne	30	23	)	)	-RRB-
cord-006460-3ayc0hne	30	24	cell	cell	NN
cord-006460-3ayc0hne	30	25	-	-	HYPH
cord-006460-3ayc0hne	30	26	produced	produce	VBN
cord-006460-3ayc0hne	30	27	NO	no	RB
cord-006460-3ayc0hne	30	28	on	on	IN
cord-006460-3ayc0hne	30	29	the	the	DT
cord-006460-3ayc0hne	30	30	one	one	CD
cord-006460-3ayc0hne	30	31	hand	hand	NN
cord-006460-3ayc0hne	30	32	,	,	,
cord-006460-3ayc0hne	30	33	and	and	CC
cord-006460-3ayc0hne	30	34	the	the	DT
cord-006460-3ayc0hne	30	35	concept	concept	NN
cord-006460-3ayc0hne	30	36	of	of	IN
cord-006460-3ayc0hne	30	37	excess	excess	JJ
cord-006460-3ayc0hne	30	38	vasodilatation	vasodilatation	NN
cord-006460-3ayc0hne	30	39	in	in	IN
cord-006460-3ayc0hne	30	40	septic	septic	JJ
cord-006460-3ayc0hne	30	41	shock	shock	NN
cord-006460-3ayc0hne	30	42	,	,	,
cord-006460-3ayc0hne	30	43	the	the	DT
cord-006460-3ayc0hne	30	44	hypothesis	hypothesis	NN
cord-006460-3ayc0hne	30	45	that	that	IN
cord-006460-3ayc0hne	30	46	this	this	DT
cord-006460-3ayc0hne	30	47	was	be	VBD
cord-006460-3ayc0hne	30	48	due	due	JJ
cord-006460-3ayc0hne	30	49	to	to	IN
cord-006460-3ayc0hne	30	50	NO	no	NN
cord-006460-3ayc0hne	30	51	and	and	CC
cord-006460-3ayc0hne	30	52	a	a	DT
cord-006460-3ayc0hne	30	53	clinical	clinical	JJ
cord-006460-3ayc0hne	30	54	trial	trial	NN
cord-006460-3ayc0hne	30	55	blocking	block	VBG
cord-006460-3ayc0hne	30	56	NO	no	DT
cord-006460-3ayc0hne	30	57	that	that	WDT
cord-006460-3ayc0hne	30	58	increased	increase	VBN
cord-006460-3ayc0hne	30	59	mortality	mortality	NN
cord-006460-3ayc0hne	30	60	on	on	IN
cord-006460-3ayc0hne	30	61	the	the	DT
cord-006460-3ayc0hne	30	62	other	other	JJ
cord-006460-3ayc0hne	30	63	.	.	.
cord-006460-3ayc0hne	31	1	Some	some	DT
cord-006460-3ayc0hne	31	2	would	would	MD
cord-006460-3ayc0hne	31	3	say	say	VB
cord-006460-3ayc0hne	31	4	that	that	IN
cord-006460-3ayc0hne	31	5	a	a	DT
cord-006460-3ayc0hne	31	6	specific	specific	JJ
cord-006460-3ayc0hne	31	7	NOS	NOS	NNP
cord-006460-3ayc0hne	31	8	,	,	,
cord-006460-3ayc0hne	31	9	such	such	JJ
cord-006460-3ayc0hne	31	10	as	as	IN
cord-006460-3ayc0hne	31	11	inducible	inducible	JJ
cord-006460-3ayc0hne	31	12	NOS	NOS	NNP
cord-006460-3ayc0hne	31	13	,	,	,
cord-006460-3ayc0hne	31	14	would	would	MD
cord-006460-3ayc0hne	31	15	have	have	VB
cord-006460-3ayc0hne	31	16	more	more	JJR
cord-006460-3ayc0hne	31	17	promise	promise	NN
cord-006460-3ayc0hne	31	18	.	.	.
cord-006460-3ayc0hne	32	1	Bloom	bloom	VB
cord-006460-3ayc0hne	32	2	[	[	-LRB-
cord-006460-3ayc0hne	32	3	5	5	CD
cord-006460-3ayc0hne	32	4	]	]	-RRB-
cord-006460-3ayc0hne	32	5	made	make	VBD
cord-006460-3ayc0hne	32	6	a	a	DT
cord-006460-3ayc0hne	32	7	comparison	comparison	NN
cord-006460-3ayc0hne	32	8	of	of	IN
cord-006460-3ayc0hne	32	9	the	the	DT
cord-006460-3ayc0hne	32	10	last	last	JJ
cord-006460-3ayc0hne	32	11	millennium	millennium	NN
cord-006460-3ayc0hne	32	12	from	from	IN
cord-006460-3ayc0hne	32	13	St.	St.	NNP
cord-006460-3ayc0hne	32	14	Thomas	Thomas	NNP
cord-006460-3ayc0hne	32	15	Aquinas	Aquinas	NNP
cord-006460-3ayc0hne	32	16	to	to	IN
cord-006460-3ayc0hne	32	17	Newton	Newton	NNP
cord-006460-3ayc0hne	32	18	and	and	CC
cord-006460-3ayc0hne	32	19	his	-PRON-	PRP$
cord-006460-3ayc0hne	32	20	Principia	Principia	NNP
cord-006460-3ayc0hne	32	21	.	.	.
cord-006460-3ayc0hne	32	22	"	"	''
cord-006460-3ayc0hne	33	1	St.	St.	NNP
cord-006460-3ayc0hne	33	2	Thomas	Thomas	NNP
cord-006460-3ayc0hne	33	3	Aquinas	Aquinas	NNP
cord-006460-3ayc0hne	33	4	'	'	POS
cord-006460-3ayc0hne	33	5	view	view	NN
cord-006460-3ayc0hne	33	6	was	be	VBD
cord-006460-3ayc0hne	33	7	that	that	IN
cord-006460-3ayc0hne	33	8	knowledge	knowledge	NN
cord-006460-3ayc0hne	33	9	is	be	VBZ
cord-006460-3ayc0hne	33	10	of	of	IN
cord-006460-3ayc0hne	33	11	two	two	CD
cord-006460-3ayc0hne	33	12	types	type	NNS
cord-006460-3ayc0hne	33	13	-that	-that	WDT
cord-006460-3ayc0hne	33	14	which	which	WDT
cord-006460-3ayc0hne	33	15	man	man	NN
cord-006460-3ayc0hne	33	16	could	could	MD
cord-006460-3ayc0hne	33	17	know	know	VB
cord-006460-3ayc0hne	33	18	and	and	CC
cord-006460-3ayc0hne	33	19	that	that	DT
cord-006460-3ayc0hne	33	20	which	which	WDT
cord-006460-3ayc0hne	33	21	was	be	VBD
cord-006460-3ayc0hne	33	22	'	'	``
cord-006460-3ayc0hne	33	23	higher	high	JJR
cord-006460-3ayc0hne	33	24	than	than	IN
cord-006460-3ayc0hne	33	25	man	man	NN
cord-006460-3ayc0hne	33	26	's	's	POS
cord-006460-3ayc0hne	33	27	knowledge	knowledge	NN
cord-006460-3ayc0hne	33	28	'	'	''
cord-006460-3ayc0hne	33	29	and	and	CC
cord-006460-3ayc0hne	33	30	not	not	RB
cord-006460-3ayc0hne	33	31	to	to	TO
cord-006460-3ayc0hne	33	32	be	be	VB
cord-006460-3ayc0hne	33	33	sought	seek	VBN
cord-006460-3ayc0hne	33	34	through	through	IN
cord-006460-3ayc0hne	33	35	reason	reason	NN
cord-006460-3ayc0hne	33	36	.	.	.
cord-006460-3ayc0hne	33	37	"	"	''
cord-006460-3ayc0hne	34	1	Newton	Newton	NNP
cord-006460-3ayc0hne	34	2	's	's	POS
cord-006460-3ayc0hne	34	3	Principia	Principia	NNP
cord-006460-3ayc0hne	34	4	,	,	,
cord-006460-3ayc0hne	34	5	on	on	IN
cord-006460-3ayc0hne	34	6	the	the	DT
cord-006460-3ayc0hne	34	7	other	other	JJ
cord-006460-3ayc0hne	34	8	hand	hand	NN
cord-006460-3ayc0hne	34	9	,	,	,
cord-006460-3ayc0hne	34	10	stated	state	VBD
cord-006460-3ayc0hne	34	11	"	"	``
cord-006460-3ayc0hne	34	12	that	that	IN
cord-006460-3ayc0hne	34	13	our	-PRON-	PRP$
cord-006460-3ayc0hne	34	14	universe	universe	NN
cord-006460-3ayc0hne	34	15	and	and	CC
cord-006460-3ayc0hne	34	16	all	all	DT
cord-006460-3ayc0hne	34	17	within	within	IN
cord-006460-3ayc0hne	34	18	it	-PRON-	PRP
cord-006460-3ayc0hne	34	19	are	be	VBP
cord-006460-3ayc0hne	34	20	indeed	indeed	RB
cord-006460-3ayc0hne	34	21	knowable	knowable	JJ
cord-006460-3ayc0hne	34	22	.	.	.
cord-006460-3ayc0hne	35	1	"	"	``
cord-006460-3ayc0hne	35	2	I	-PRON-	PRP
cord-006460-3ayc0hne	35	3	add	add	VBP
cord-006460-3ayc0hne	35	4	to	to	IN
cord-006460-3ayc0hne	35	5	this	this	DT
cord-006460-3ayc0hne	35	6	that	that	IN
cord-006460-3ayc0hne	35	7	all	all	DT
cord-006460-3ayc0hne	35	8	things	thing	NNS
cord-006460-3ayc0hne	35	9	may	may	MD
cord-006460-3ayc0hne	35	10	be	be	VB
cord-006460-3ayc0hne	35	11	knowable	knowable	JJ
cord-006460-3ayc0hne	35	12	,	,	,
cord-006460-3ayc0hne	35	13	but	but	CC
cord-006460-3ayc0hne	35	14	perhaps	perhaps	RB
cord-006460-3ayc0hne	35	15	not	not	RB
cord-006460-3ayc0hne	35	16	doable	doable	JJ
cord-006460-3ayc0hne	35	17	.	.	.
cord-006460-3ayc0hne	36	1	The	the	DT
cord-006460-3ayc0hne	36	2	tremendous	tremendous	JJ
cord-006460-3ayc0hne	36	3	amount	amount	NN
cord-006460-3ayc0hne	36	4	of	of	IN
cord-006460-3ayc0hne	36	5	information	information	NN
cord-006460-3ayc0hne	36	6	generated	generate	VBN
cord-006460-3ayc0hne	36	7	by	by	IN
cord-006460-3ayc0hne	36	8	molecular	molecular	JJ
cord-006460-3ayc0hne	36	9	biology	biology	NN
cord-006460-3ayc0hne	37	1	-the	-the	NFP
cord-006460-3ayc0hne	37	2	techniques	technique	NNS
cord-006460-3ayc0hne	37	3	of	of	IN
cord-006460-3ayc0hne	37	4	DNA	dna	NN
cord-006460-3ayc0hne	37	5	identification	identification	NN
cord-006460-3ayc0hne	37	6	;	;	:
cord-006460-3ayc0hne	37	7	the	the	DT
cord-006460-3ayc0hne	37	8	human	human	JJ
cord-006460-3ayc0hne	37	9	genome	genome	NN
cord-006460-3ayc0hne	37	10	project	project	NN
cord-006460-3ayc0hne	37	11	;	;	:
cord-006460-3ayc0hne	37	12	mediators	mediator	NNS
cord-006460-3ayc0hne	37	13	;	;	:
cord-006460-3ayc0hne	37	14	signal	signal	NN
cord-006460-3ayc0hne	37	15	transduction	transduction	NN
cord-006460-3ayc0hne	37	16	;	;	:
cord-006460-3ayc0hne	37	17	the	the	DT
cord-006460-3ayc0hne	37	18	immune	immune	JJ
cord-006460-3ayc0hne	37	19	system	system	NN
cord-006460-3ayc0hne	37	20	;	;	:
cord-006460-3ayc0hne	37	21	the	the	DT
cord-006460-3ayc0hne	37	22	response	response	NN
cord-006460-3ayc0hne	37	23	to	to	IN
cord-006460-3ayc0hne	37	24	injury	injury	NN
cord-006460-3ayc0hne	37	25	;	;	:
cord-006460-3ayc0hne	37	26	organ	organ	NN
cord-006460-3ayc0hne	37	27	,	,	,
cord-006460-3ayc0hne	37	28	cell	cell	NN
cord-006460-3ayc0hne	37	29	,	,	,
cord-006460-3ayc0hne	37	30	endothelium	endothelium	NN
cord-006460-3ayc0hne	37	31	and	and	CC
cord-006460-3ayc0hne	37	32	membrane	membrane	NN
cord-006460-3ayc0hne	37	33	function	function	NN
cord-006460-3ayc0hne	37	34	-all	-all	:
cord-006460-3ayc0hne	37	35	stretch	stretch	VBP
cord-006460-3ayc0hne	37	36	the	the	DT
cord-006460-3ayc0hne	37	37	imagination	imagination	NN
cord-006460-3ayc0hne	37	38	.	.	.
cord-006460-3ayc0hne	38	1	There	there	EX
cord-006460-3ayc0hne	38	2	have	have	VBP
cord-006460-3ayc0hne	38	3	been	be	VBN
cord-006460-3ayc0hne	38	4	improvements	improvement	NNS
cord-006460-3ayc0hne	38	5	in	in	IN
cord-006460-3ayc0hne	38	6	the	the	DT
cord-006460-3ayc0hne	38	7	way	way	NN
cord-006460-3ayc0hne	38	8	we	-PRON-	PRP
cord-006460-3ayc0hne	38	9	care	care	VBP
cord-006460-3ayc0hne	38	10	for	for	IN
cord-006460-3ayc0hne	38	11	patients	patient	NNS
cord-006460-3ayc0hne	38	12	,	,	,
cord-006460-3ayc0hne	38	13	but	but	CC
cord-006460-3ayc0hne	38	14	they	-PRON-	PRP
cord-006460-3ayc0hne	38	15	have	have	VBP
cord-006460-3ayc0hne	38	16	been	be	VBN
cord-006460-3ayc0hne	38	17	modest	modest	JJ
cord-006460-3ayc0hne	38	18	and	and	CC
cord-006460-3ayc0hne	38	19	slow	slow	JJ
cord-006460-3ayc0hne	38	20	and	and	CC
cord-006460-3ayc0hne	38	21	have	have	VBP
cord-006460-3ayc0hne	38	22	not	not	RB
cord-006460-3ayc0hne	38	23	been	be	VBN
cord-006460-3ayc0hne	38	24	easy	easy	JJ
cord-006460-3ayc0hne	38	25	to	to	TO
cord-006460-3ayc0hne	38	26	document	document	VB
cord-006460-3ayc0hne	38	27	.	.	.
cord-006460-3ayc0hne	39	1	It	-PRON-	PRP
cord-006460-3ayc0hne	39	2	has	have	VBZ
cord-006460-3ayc0hne	39	3	not	not	RB
cord-006460-3ayc0hne	39	4	been	be	VBN
cord-006460-3ayc0hne	39	5	possible	possible	JJ
cord-006460-3ayc0hne	39	6	to	to	TO
cord-006460-3ayc0hne	39	7	apply	apply	VB
cord-006460-3ayc0hne	39	8	most	most	JJS
cord-006460-3ayc0hne	39	9	of	of	IN
cord-006460-3ayc0hne	39	10	the	the	DT
cord-006460-3ayc0hne	39	11	information	information	NN
cord-006460-3ayc0hne	39	12	of	of	IN
cord-006460-3ayc0hne	39	13	molecular	molecular	JJ
cord-006460-3ayc0hne	39	14	biology	biology	NN
cord-006460-3ayc0hne	39	15	to	to	IN
cord-006460-3ayc0hne	39	16	patient	patient	JJ
cord-006460-3ayc0hne	39	17	care	care	NN
cord-006460-3ayc0hne	39	18	.	.	.
cord-006460-3ayc0hne	40	1	I	-PRON-	PRP
cord-006460-3ayc0hne	40	2	believe	believe	VBP
cord-006460-3ayc0hne	40	3	that	that	IN
cord-006460-3ayc0hne	40	4	there	there	EX
cord-006460-3ayc0hne	40	5	are	be	VBP
cord-006460-3ayc0hne	40	6	three	three	CD
cord-006460-3ayc0hne	40	7	major	major	JJ
cord-006460-3ayc0hne	40	8	reasons	reason	NNS
cord-006460-3ayc0hne	40	9	for	for	IN
cord-006460-3ayc0hne	40	10	this	this	DT
cord-006460-3ayc0hne	40	11	discrepancy	discrepancy	NN
cord-006460-3ayc0hne	40	12	.	.	.
cord-006460-3ayc0hne	41	1	You	-PRON-	PRP
cord-006460-3ayc0hne	41	2	may	may	MD
cord-006460-3ayc0hne	41	3	have	have	VB
cord-006460-3ayc0hne	41	4	others	other	NNS
cord-006460-3ayc0hne	41	5	.	.	.
cord-006460-3ayc0hne	42	1	1	1	LS
cord-006460-3ayc0hne	42	2	.	.	.
cord-006460-3ayc0hne	43	1	There	there	EX
cord-006460-3ayc0hne	43	2	are	be	VBP
cord-006460-3ayc0hne	43	3	differences	difference	NNS
cord-006460-3ayc0hne	43	4	between	between	IN
cord-006460-3ayc0hne	43	5	individuals	individual	NNS
cord-006460-3ayc0hne	43	6	(	(	-LRB-
cord-006460-3ayc0hne	43	7	diversity	diversity	NN
cord-006460-3ayc0hne	43	8	)	)	-RRB-
cord-006460-3ayc0hne	43	9	which	which	WDT
cord-006460-3ayc0hne	43	10	may	may	MD
cord-006460-3ayc0hne	43	11	not	not	RB
cord-006460-3ayc0hne	43	12	be	be	VB
cord-006460-3ayc0hne	43	13	measurable	measurable	JJ
cord-006460-3ayc0hne	43	14	and	and	CC
cord-006460-3ayc0hne	43	15	which	which	WDT
cord-006460-3ayc0hne	43	16	are	be	VBP
cord-006460-3ayc0hne	43	17	not	not	RB
cord-006460-3ayc0hne	43	18	taken	take	VBN
cord-006460-3ayc0hne	43	19	into	into	IN
cord-006460-3ayc0hne	43	20	consideration	consideration	NN
cord-006460-3ayc0hne	43	21	in	in	IN
cord-006460-3ayc0hne	43	22	therapy	therapy	NN
cord-006460-3ayc0hne	43	23	and	and	CC
cord-006460-3ayc0hne	43	24	clinical	clinical	JJ
cord-006460-3ayc0hne	43	25	trials	trial	NNS
cord-006460-3ayc0hne	43	26	.	.	.
cord-006460-3ayc0hne	44	1	We	-PRON-	PRP
cord-006460-3ayc0hne	44	2	do	do	VBP
cord-006460-3ayc0hne	44	3	not	not	RB
cord-006460-3ayc0hne	44	4	look	look	VB
cord-006460-3ayc0hne	44	5	,	,	,
cord-006460-3ayc0hne	44	6	act	act	VB
cord-006460-3ayc0hne	44	7	or	or	CC
cord-006460-3ayc0hne	44	8	respond	respond	VB
cord-006460-3ayc0hne	44	9	alike	alike	RB
cord-006460-3ayc0hne	44	10	.	.	.
cord-006460-3ayc0hne	45	1	Our	-PRON-	PRP$
cord-006460-3ayc0hne	45	2	genetic	genetic	JJ
cord-006460-3ayc0hne	45	3	differences	difference	NNS
cord-006460-3ayc0hne	45	4	dictate	dictate	VBP
cord-006460-3ayc0hne	45	5	how	how	WRB
cord-006460-3ayc0hne	45	6	we	-PRON-	PRP
cord-006460-3ayc0hne	45	7	will	will	MD
cord-006460-3ayc0hne	45	8	respond	respond	VB
cord-006460-3ayc0hne	45	9	to	to	IN
cord-006460-3ayc0hne	45	10	injury	injury	NN
cord-006460-3ayc0hne	45	11	,	,	,
cord-006460-3ayc0hne	45	12	an	an	DT
cord-006460-3ayc0hne	45	13	operation	operation	NN
cord-006460-3ayc0hne	45	14	,	,	,
cord-006460-3ayc0hne	45	15	infection	infection	NN
cord-006460-3ayc0hne	45	16	or	or	CC
cord-006460-3ayc0hne	45	17	stress	stress	NN
cord-006460-3ayc0hne	45	18	.	.	.
cord-006460-3ayc0hne	46	1	Genetic	genetic	JJ
cord-006460-3ayc0hne	46	2	studies	study	NNS
cord-006460-3ayc0hne	46	3	are	be	VBP
cord-006460-3ayc0hne	46	4	now	now	RB
cord-006460-3ayc0hne	46	5	beginning	begin	VBG
cord-006460-3ayc0hne	46	6	to	to	TO
cord-006460-3ayc0hne	46	7	describe	describe	VB
cord-006460-3ayc0hne	46	8	these	these	DT
cord-006460-3ayc0hne	46	9	extensive	extensive	JJ
cord-006460-3ayc0hne	46	10	genomic	genomic	JJ
cord-006460-3ayc0hne	46	11	differences	difference	NNS
cord-006460-3ayc0hne	46	12	.	.	.
cord-006460-3ayc0hne	47	1	Sir	Sir	NNP
cord-006460-3ayc0hne	47	2	William	William	NNP
cord-006460-3ayc0hne	47	3	Osler	Osler	NNP
cord-006460-3ayc0hne	47	4	once	once	RB
cord-006460-3ayc0hne	47	5	said	say	VBD
cord-006460-3ayc0hne	47	6	,	,	,
cord-006460-3ayc0hne	47	7	"	"	``
cord-006460-3ayc0hne	47	8	As	as	IN
cord-006460-3ayc0hne	47	9	no	no	DT
cord-006460-3ayc0hne	47	10	two	two	CD
cord-006460-3ayc0hne	47	11	faces	face	NNS
cord-006460-3ayc0hne	47	12	,	,	,
cord-006460-3ayc0hne	47	13	so	so	RB
cord-006460-3ayc0hne	47	14	no	no	DT
cord-006460-3ayc0hne	47	15	two	two	CD
cord-006460-3ayc0hne	47	16	cases	case	NNS
cord-006460-3ayc0hne	47	17	are	be	VBP
cord-006460-3ayc0hne	47	18	alike	alike	RB
cord-006460-3ayc0hne	47	19	in	in	IN
cord-006460-3ayc0hne	47	20	all	all	DT
cord-006460-3ayc0hne	47	21	respects	respect	NNS
cord-006460-3ayc0hne	47	22	,	,	,
cord-006460-3ayc0hne	47	23	and	and	CC
cord-006460-3ayc0hne	47	24	unfortunately	unfortunately	RB
cord-006460-3ayc0hne	47	25	it	-PRON-	PRP
cord-006460-3ayc0hne	47	26	is	be	VBZ
cord-006460-3ayc0hne	47	27	not	not	RB
cord-006460-3ayc0hne	47	28	only	only	RB
cord-006460-3ayc0hne	47	29	the	the	DT
cord-006460-3ayc0hne	47	30	disease	disease	NN
cord-006460-3ayc0hne	47	31	itself	-PRON-	PRP
cord-006460-3ayc0hne	47	32	which	which	WDT
cord-006460-3ayc0hne	47	33	is	be	VBZ
cord-006460-3ayc0hne	47	34	so	so	RB
cord-006460-3ayc0hne	47	35	varied	varied	JJ
cord-006460-3ayc0hne	47	36	but	but	CC
cord-006460-3ayc0hne	47	37	the	the	DT
cord-006460-3ayc0hne	47	38	subjects	subject	NNS
cord-006460-3ayc0hne	47	39	themselves	-PRON-	PRP
cord-006460-3ayc0hne	47	40	have	have	VBP
cord-006460-3ayc0hne	47	41	peculiarities	peculiarity	NNS
cord-006460-3ayc0hne	47	42	which	which	WDT
cord-006460-3ayc0hne	47	43	modify	modify	VBP
cord-006460-3ayc0hne	47	44	its	-PRON-	PRP$
cord-006460-3ayc0hne	47	45	action	action	NN
cord-006460-3ayc0hne	47	46	"	"	''
cord-006460-3ayc0hne	47	47	[	[	-LRB-
cord-006460-3ayc0hne	47	48	6	6	CD
cord-006460-3ayc0hne	47	49	]	]	-RRB-
cord-006460-3ayc0hne	47	50	.	.	.
cord-006460-3ayc0hne	48	1	2	2	LS
cord-006460-3ayc0hne	48	2	.	.	.
cord-006460-3ayc0hne	49	1	Our	-PRON-	PRP$
cord-006460-3ayc0hne	49	2	experiences	experience	NNS
cord-006460-3ayc0hne	49	3	in	in	IN
cord-006460-3ayc0hne	49	4	life	life	NN
cord-006460-3ayc0hne	49	5	are	be	VBP
cord-006460-3ayc0hne	49	6	all	all	RB
cord-006460-3ayc0hne	49	7	different	different	JJ
cord-006460-3ayc0hne	49	8	-our	-our	ADD
cord-006460-3ayc0hne	49	9	exposure	exposure	NN
cord-006460-3ayc0hne	49	10	to	to	IN
cord-006460-3ayc0hne	49	11	antigens	antigen	NNS
cord-006460-3ayc0hne	49	12	,	,	,
cord-006460-3ayc0hne	49	13	prior	prior	JJ
cord-006460-3ayc0hne	49	14	illness	illness	NN
cord-006460-3ayc0hne	49	15	and	and	CC
cord-006460-3ayc0hne	49	16	injury	injury	NN
cord-006460-3ayc0hne	49	17	;	;	:
cord-006460-3ayc0hne	49	18	our	-PRON-	PRP$
cord-006460-3ayc0hne	49	19	immune	immune	JJ
cord-006460-3ayc0hne	49	20	history	history	NN
cord-006460-3ayc0hne	49	21	;	;	:
cord-006460-3ayc0hne	49	22	and	and	CC
cord-006460-3ayc0hne	49	23	our	-PRON-	PRP$
cord-006460-3ayc0hne	49	24	group	group	NN
cord-006460-3ayc0hne	49	25	experiences	experience	NNS
cord-006460-3ayc0hne	49	26	.	.	.
cord-006460-3ayc0hne	50	1	We	-PRON-	PRP
cord-006460-3ayc0hne	50	2	are	be	VBP
cord-006460-3ayc0hne	50	3	not	not	RB
cord-006460-3ayc0hne	50	4	genetically	genetically	RB
cord-006460-3ayc0hne	50	5	pure	pure	JJ
cord-006460-3ayc0hne	50	6	animals	animal	NNS
cord-006460-3ayc0hne	50	7	living	live	VBG
cord-006460-3ayc0hne	50	8	in	in	IN
cord-006460-3ayc0hne	50	9	the	the	DT
cord-006460-3ayc0hne	50	10	same	same	JJ
cord-006460-3ayc0hne	50	11	cage	cage	NN
cord-006460-3ayc0hne	50	12	for	for	IN
cord-006460-3ayc0hne	50	13	our	-PRON-	PRP$
cord-006460-3ayc0hne	50	14	lifetimes	lifetime	NNS
cord-006460-3ayc0hne	50	15	before	before	IN
cord-006460-3ayc0hne	50	16	an	an	DT
cord-006460-3ayc0hne	50	17	insult	insult	NN
cord-006460-3ayc0hne	50	18	occurs	occur	VBZ
cord-006460-3ayc0hne	50	19	.	.	.
cord-006460-3ayc0hne	51	1	There	there	EX
cord-006460-3ayc0hne	51	2	is	be	VBZ
cord-006460-3ayc0hne	51	3	also	also	RB
cord-006460-3ayc0hne	51	4	much	much	JJ
cord-006460-3ayc0hne	51	5	evidence	evidence	NN
cord-006460-3ayc0hne	51	6	for	for	IN
cord-006460-3ayc0hne	51	7	these	these	DT
cord-006460-3ayc0hne	51	8	powerful	powerful	JJ
cord-006460-3ayc0hne	51	9	and	and	CC
cord-006460-3ayc0hne	51	10	complex	complex	JJ
cord-006460-3ayc0hne	51	11	acquired	acquire	VBN
cord-006460-3ayc0hne	51	12	differences	difference	NNS
cord-006460-3ayc0hne	51	13	and	and	CC
cord-006460-3ayc0hne	51	14	exposures	exposure	NNS
cord-006460-3ayc0hne	51	15	.	.	.
cord-006460-3ayc0hne	52	1	3	3	LS
cord-006460-3ayc0hne	52	2	.	.	.
cord-006460-3ayc0hne	53	1	We	-PRON-	PRP
cord-006460-3ayc0hne	53	2	have	have	VBP
cord-006460-3ayc0hne	53	3	tried	try	VBN
cord-006460-3ayc0hne	53	4	to	to	TO
cord-006460-3ayc0hne	53	5	lump	lump	VB
cord-006460-3ayc0hne	53	6	together	together	RB
cord-006460-3ayc0hne	53	7	and	and	CC
cord-006460-3ayc0hne	53	8	treat	treat	VB
cord-006460-3ayc0hne	53	9	human	human	JJ
cord-006460-3ayc0hne	53	10	abnormalities	abnormality	NNS
cord-006460-3ayc0hne	53	11	according	accord	VBG
cord-006460-3ayc0hne	53	12	to	to	IN
cord-006460-3ayc0hne	53	13	symptoms	symptom	NNS
cord-006460-3ayc0hne	53	14	and	and	CC
cord-006460-3ayc0hne	53	15	signs	sign	NNS
cord-006460-3ayc0hne	53	16	rather	rather	RB
cord-006460-3ayc0hne	53	17	than	than	IN
cord-006460-3ayc0hne	53	18	to	to	IN
cord-006460-3ayc0hne	53	19	the	the	DT
cord-006460-3ayc0hne	53	20	basic	basic	JJ
cord-006460-3ayc0hne	53	21	causes	cause	NNS
cord-006460-3ayc0hne	53	22	of	of	IN
cord-006460-3ayc0hne	53	23	their	-PRON-	PRP$
cord-006460-3ayc0hne	53	24	diseases	disease	NNS
cord-006460-3ayc0hne	53	25	-we	-we	:
cord-006460-3ayc0hne	53	26	have	have	VBP
cord-006460-3ayc0hne	53	27	tried	try	VBN
cord-006460-3ayc0hne	53	28	to	to	TO
cord-006460-3ayc0hne	53	29	treat	treat	VB
cord-006460-3ayc0hne	53	30	inflammation	inflammation	NN
cord-006460-3ayc0hne	53	31	,	,	,
cord-006460-3ayc0hne	53	32	sepsis	sepsis	NN
cord-006460-3ayc0hne	53	33	,	,	,
cord-006460-3ayc0hne	53	34	systemic	systemic	JJ
cord-006460-3ayc0hne	53	35	inflammatory	inflammatory	JJ
cord-006460-3ayc0hne	53	36	response	response	NN
cord-006460-3ayc0hne	53	37	syndrome	syndrome	NN
cord-006460-3ayc0hne	53	38	(	(	-LRB-
cord-006460-3ayc0hne	53	39	SIRS	SIRS	NNP
cord-006460-3ayc0hne	53	40	)	)	-RRB-
cord-006460-3ayc0hne	53	41	,	,	,
cord-006460-3ayc0hne	53	42	and	and	CC
cord-006460-3ayc0hne	53	43	multiple	multiple	JJ
cord-006460-3ayc0hne	53	44	organ	organ	NN
cord-006460-3ayc0hne	53	45	dysfunction	dysfunction	NN
cord-006460-3ayc0hne	53	46	syndrome	syndrome	NN
cord-006460-3ayc0hne	53	47	(	(	-LRB-
cord-006460-3ayc0hne	53	48	MODS	MODS	NNP
cord-006460-3ayc0hne	53	49	)	)	-RRB-
cord-006460-3ayc0hne	53	50	rather	rather	RB
cord-006460-3ayc0hne	53	51	than	than	IN
cord-006460-3ayc0hne	53	52	what	what	WP
cord-006460-3ayc0hne	53	53	caused	cause	VBD
cord-006460-3ayc0hne	53	54	them	-PRON-	PRP
cord-006460-3ayc0hne	53	55	;	;	,
cord-006460-3ayc0hne	53	56	perforated	perforated	JJ
cord-006460-3ayc0hne	53	57	diverticulitis	diverticulitis	NN
cord-006460-3ayc0hne	53	58	is	be	VBZ
cord-006460-3ayc0hne	53	59	not	not	RB
cord-006460-3ayc0hne	53	60	acute	acute	JJ
cord-006460-3ayc0hne	53	61	pancreatitis	pancreatitis	NN
cord-006460-3ayc0hne	53	62	and	and	CC
cord-006460-3ayc0hne	53	63	neither	neither	DT
cord-006460-3ayc0hne	53	64	are	be	VBP
cord-006460-3ayc0hne	53	65	ventilator	ventilator	NN
cord-006460-3ayc0hne	53	66	-	-	HYPH
cord-006460-3ayc0hne	53	67	associated	associate	VBN
cord-006460-3ayc0hne	53	68	pneumonia	pneumonia	NN
cord-006460-3ayc0hne	53	69	and	and	CC
cord-006460-3ayc0hne	53	70	appendicitis	appendicitis	NN
cord-006460-3ayc0hne	53	71	.	.	.
cord-006460-3ayc0hne	54	1	All	all	DT
cord-006460-3ayc0hne	54	2	of	of	IN
cord-006460-3ayc0hne	54	3	these	these	DT
cord-006460-3ayc0hne	54	4	differences	difference	NNS
cord-006460-3ayc0hne	54	5	and	and	CC
cord-006460-3ayc0hne	54	6	factors	factor	NNS
cord-006460-3ayc0hne	54	7	complicate	complicate	VBP
cord-006460-3ayc0hne	54	8	our	-PRON-	PRP$
cord-006460-3ayc0hne	54	9	scientific	scientific	JJ
cord-006460-3ayc0hne	54	10	understanding	understanding	NN
cord-006460-3ayc0hne	54	11	and	and	CC
cord-006460-3ayc0hne	54	12	make	make	VB
cord-006460-3ayc0hne	54	13	developing	develop	VBG
cord-006460-3ayc0hne	54	14	appropriate	appropriate	JJ
cord-006460-3ayc0hne	54	15	therapy	therapy	NN
cord-006460-3ayc0hne	54	16	for	for	IN
cord-006460-3ayc0hne	54	17	patients	patient	NNS
cord-006460-3ayc0hne	54	18	based	base	VBN
cord-006460-3ayc0hne	54	19	on	on	IN
cord-006460-3ayc0hne	54	20	molecular	molecular	JJ
cord-006460-3ayc0hne	54	21	biology	biology	NN
cord-006460-3ayc0hne	54	22	more	more	RBR
cord-006460-3ayc0hne	54	23	complex	complex	JJ
cord-006460-3ayc0hne	54	24	.	.	.
cord-006460-3ayc0hne	55	1	The	the	DT
cord-006460-3ayc0hne	55	2	wonders	wonder	NNS
cord-006460-3ayc0hne	55	3	of	of	IN
cord-006460-3ayc0hne	55	4	science	science	NN
cord-006460-3ayc0hne	55	5	are	be	VBP
cord-006460-3ayc0hne	55	6	revealing	reveal	VBG
cord-006460-3ayc0hne	55	7	the	the	DT
cord-006460-3ayc0hne	55	8	complexities	complexity	NNS
cord-006460-3ayc0hne	55	9	of	of	IN
cord-006460-3ayc0hne	55	10	human	human	JJ
cord-006460-3ayc0hne	55	11	disease	disease	NN
cord-006460-3ayc0hne	55	12	.	.	.
cord-006460-3ayc0hne	56	1	The	the	DT
cord-006460-3ayc0hne	56	2	picture	picture	NN
cord-006460-3ayc0hne	56	3	is	be	VBZ
cord-006460-3ayc0hne	56	4	becoming	become	VBG
cord-006460-3ayc0hne	56	5	clearer	clear	JJR
cord-006460-3ayc0hne	56	6	-genetic	-genetic	JJ
cord-006460-3ayc0hne	56	7	polymorphisms	polymorphism	NNS
cord-006460-3ayc0hne	56	8	,	,	,
cord-006460-3ayc0hne	56	9	antigen	antigen	NN
cord-006460-3ayc0hne	56	10	exposure	exposure	NN
cord-006460-3ayc0hne	56	11	,	,	,
cord-006460-3ayc0hne	56	12	etc	etc	FW
cord-006460-3ayc0hne	56	13	.	.	.
cord-006460-3ayc0hne	57	1	[	[	-LRB-
cord-006460-3ayc0hne	57	2	7	7	CD
cord-006460-3ayc0hne	57	3	]	]	-RRB-
cord-006460-3ayc0hne	57	4	.	.	.
cord-006460-3ayc0hne	58	1	Patient	patient	JJ
cord-006460-3ayc0hne	58	2	care	care	NN
cord-006460-3ayc0hne	58	3	is	be	VBZ
cord-006460-3ayc0hne	58	4	improving	improve	VBG
cord-006460-3ayc0hne	58	5	,	,	,
cord-006460-3ayc0hne	58	6	but	but	CC
cord-006460-3ayc0hne	58	7	slowly	slowly	RB
cord-006460-3ayc0hne	58	8	.	.	.
cord-006460-3ayc0hne	59	1	This	this	DT
cord-006460-3ayc0hne	59	2	should	should	MD
cord-006460-3ayc0hne	59	3	not	not	RB
cord-006460-3ayc0hne	59	4	be	be	VB
cord-006460-3ayc0hne	59	5	discouraging	discourage	VBG
cord-006460-3ayc0hne	59	6	,	,	,
cord-006460-3ayc0hne	59	7	but	but	CC
cord-006460-3ayc0hne	59	8	we	-PRON-	PRP
cord-006460-3ayc0hne	59	9	must	must	MD
cord-006460-3ayc0hne	59	10	try	try	VB
cord-006460-3ayc0hne	59	11	harder	hard	RBR
cord-006460-3ayc0hne	59	12	.	.	.
cord-006460-3ayc0hne	60	1	Next	next	RB
cord-006460-3ayc0hne	60	2	,	,	,
cord-006460-3ayc0hne	60	3	a	a	DT
cord-006460-3ayc0hne	60	4	word	word	NN
cord-006460-3ayc0hne	60	5	about	about	IN
cord-006460-3ayc0hne	60	6	MOF	MOF	NNP
cord-006460-3ayc0hne	60	7	,	,	,
cord-006460-3ayc0hne	60	8	its	-PRON-	PRP$
cord-006460-3ayc0hne	60	9	meaning	meaning	NN
cord-006460-3ayc0hne	60	10	and	and	CC
cord-006460-3ayc0hne	60	11	its	-PRON-	PRP$
cord-006460-3ayc0hne	60	12	relationship	relationship	NN
cord-006460-3ayc0hne	60	13	to	to	IN
cord-006460-3ayc0hne	60	14	these	these	DT
cord-006460-3ayc0hne	60	15	complexities	complexity	NNS
cord-006460-3ayc0hne	60	16	.	.	.
cord-006460-3ayc0hne	61	1	In	in	IN
cord-006460-3ayc0hne	61	2	1975	1975	CD
cord-006460-3ayc0hne	61	3	,	,	,
cord-006460-3ayc0hne	61	4	I	-PRON-	PRP
cord-006460-3ayc0hne	61	5	wrote	write	VBD
cord-006460-3ayc0hne	61	6	an	an	DT
cord-006460-3ayc0hne	61	7	editorial	editorial	NN
cord-006460-3ayc0hne	61	8	entitled	entitle	VBN
cord-006460-3ayc0hne	61	9	"	"	``
cord-006460-3ayc0hne	61	10	Multiple	multiple	JJ
cord-006460-3ayc0hne	61	11	,	,	,
cord-006460-3ayc0hne	61	12	Progressive	progressive	JJ
cord-006460-3ayc0hne	61	13	or	or	CC
cord-006460-3ayc0hne	61	14	Sequential	Sequential	NNP
cord-006460-3ayc0hne	61	15	Systems	Systems	NNPS
cord-006460-3ayc0hne	61	16	Failure	failure	NN
cord-006460-3ayc0hne	61	17	:	:	:
cord-006460-3ayc0hne	61	18	A	a	DT
cord-006460-3ayc0hne	61	19	Syndrome	syndrome	NN
cord-006460-3ayc0hne	61	20	of	of	IN
cord-006460-3ayc0hne	61	21	the	the	DT
cord-006460-3ayc0hne	61	22	1970s	1970	NNS
cord-006460-3ayc0hne	61	23	"	"	''
cord-006460-3ayc0hne	61	24	[	[	-LRB-
cord-006460-3ayc0hne	61	25	8	8	CD
cord-006460-3ayc0hne	61	26	]	]	-RRB-
cord-006460-3ayc0hne	61	27	.	.	.
cord-006460-3ayc0hne	62	1	In	in	IN
cord-006460-3ayc0hne	62	2	it	-PRON-	PRP
cord-006460-3ayc0hne	62	3	,	,	,
cord-006460-3ayc0hne	62	4	I	-PRON-	PRP
cord-006460-3ayc0hne	62	5	described	describe	VBD
cord-006460-3ayc0hne	62	6	three	three	CD
cord-006460-3ayc0hne	62	7	examples	example	NNS
cord-006460-3ayc0hne	62	8	of	of	IN
cord-006460-3ayc0hne	62	9	patients	patient	NNS
cord-006460-3ayc0hne	62	10	that	that	IN
cord-006460-3ayc0hne	62	11	I	-PRON-	PRP
cord-006460-3ayc0hne	62	12	observed	observe	VBD
cord-006460-3ayc0hne	62	13	who	who	WP
cord-006460-3ayc0hne	62	14	developed	develop	VBD
cord-006460-3ayc0hne	62	15	multiple	multiple	JJ
cord-006460-3ayc0hne	62	16	organ	organ	NN
cord-006460-3ayc0hne	62	17	problems	problem	NNS
cord-006460-3ayc0hne	62	18	.	.	.
cord-006460-3ayc0hne	63	1	One	one	CD
cord-006460-3ayc0hne	63	2	patient	patient	NN
cord-006460-3ayc0hne	63	3	had	have	VBD
cord-006460-3ayc0hne	63	4	acute	acute	JJ
cord-006460-3ayc0hne	63	5	hemorrhagic	hemorrhagic	JJ
cord-006460-3ayc0hne	63	6	pancreatitis	pancreatitis	NN
cord-006460-3ayc0hne	63	7	.	.	.
cord-006460-3ayc0hne	64	1	Another	another	DT
cord-006460-3ayc0hne	64	2	had	have	VBD
cord-006460-3ayc0hne	64	3	a	a	DT
cord-006460-3ayc0hne	64	4	colon	colon	NN
cord-006460-3ayc0hne	64	5	resection	resection	NN
cord-006460-3ayc0hne	64	6	and	and	CC
cord-006460-3ayc0hne	64	7	developed	develop	VBD
cord-006460-3ayc0hne	64	8	an	an	DT
cord-006460-3ayc0hne	64	9	anastomotic	anastomotic	JJ
cord-006460-3ayc0hne	64	10	leak	leak	NN
cord-006460-3ayc0hne	64	11	leading	lead	VBG
cord-006460-3ayc0hne	64	12	to	to	IN
cord-006460-3ayc0hne	64	13	peritonitis	peritonitis	NN
cord-006460-3ayc0hne	64	14	.	.	.
cord-006460-3ayc0hne	65	1	A	a	DT
cord-006460-3ayc0hne	65	2	third	third	JJ
cord-006460-3ayc0hne	65	3	was	be	VBD
cord-006460-3ayc0hne	65	4	a	a	DT
cord-006460-3ayc0hne	65	5	patient	patient	NN
cord-006460-3ayc0hne	65	6	of	of	IN
cord-006460-3ayc0hne	65	7	mine	-PRON-	PRP
cord-006460-3ayc0hne	65	8	in	in	IN
cord-006460-3ayc0hne	65	9	whom	whom	WP
cord-006460-3ayc0hne	65	10	I	-PRON-	PRP
cord-006460-3ayc0hne	65	11	had	have	VBD
cord-006460-3ayc0hne	65	12	performed	perform	VBN
cord-006460-3ayc0hne	65	13	a	a	DT
cord-006460-3ayc0hne	65	14	double	double	JJ
cord-006460-3ayc0hne	65	15	valve	valve	NN
cord-006460-3ayc0hne	65	16	replacement	replacement	NN
cord-006460-3ayc0hne	65	17	(	(	-LRB-
cord-006460-3ayc0hne	65	18	aortic	aortic	JJ
cord-006460-3ayc0hne	65	19	and	and	CC
cord-006460-3ayc0hne	65	20	mitral	mitral	JJ
cord-006460-3ayc0hne	65	21	valves	valve	NNS
cord-006460-3ayc0hne	65	22	)	)	-RRB-
cord-006460-3ayc0hne	65	23	;	;	:
cord-006460-3ayc0hne	65	24	the	the	DT
cord-006460-3ayc0hne	65	25	patient	patient	NN
cord-006460-3ayc0hne	65	26	had	have	VBD
cord-006460-3ayc0hne	65	27	an	an	DT
cord-006460-3ayc0hne	65	28	extremely	extremely	RB
cord-006460-3ayc0hne	65	29	low	low	JJ
cord-006460-3ayc0hne	65	30	cardiac	cardiac	JJ
cord-006460-3ayc0hne	65	31	output	output	NN
cord-006460-3ayc0hne	65	32	for	for	IN
cord-006460-3ayc0hne	65	33	the	the	DT
cord-006460-3ayc0hne	65	34	next	next	JJ
cord-006460-3ayc0hne	65	35	6	6	CD
cord-006460-3ayc0hne	65	36	weeks	week	NNS
cord-006460-3ayc0hne	65	37	or	or	CC
cord-006460-3ayc0hne	65	38	so	so	RB
cord-006460-3ayc0hne	65	39	and	and	CC
cord-006460-3ayc0hne	65	40	died	die	VBD
cord-006460-3ayc0hne	65	41	.	.	.
cord-006460-3ayc0hne	66	1	I	-PRON-	PRP
cord-006460-3ayc0hne	66	2	reviewed	review	VBD
cord-006460-3ayc0hne	66	3	the	the	DT
cord-006460-3ayc0hne	66	4	clinical	clinical	JJ
cord-006460-3ayc0hne	66	5	course	course	NN
cord-006460-3ayc0hne	66	6	of	of	IN
cord-006460-3ayc0hne	66	7	these	these	DT
cord-006460-3ayc0hne	66	8	patients	patient	NNS
cord-006460-3ayc0hne	66	9	and	and	CC
cord-006460-3ayc0hne	66	10	then	then	RB
cord-006460-3ayc0hne	66	11	the	the	DT
cord-006460-3ayc0hne	66	12	autopsy	autopsy	JJ
cord-006460-3ayc0hne	66	13	findings	finding	NNS
cord-006460-3ayc0hne	66	14	.	.	.
cord-006460-3ayc0hne	67	1	In	in	IN
cord-006460-3ayc0hne	67	2	one	one	CD
cord-006460-3ayc0hne	67	3	patient	patient	NN
cord-006460-3ayc0hne	67	4	,	,	,
cord-006460-3ayc0hne	67	5	for	for	IN
cord-006460-3ayc0hne	67	6	example	example	NN
cord-006460-3ayc0hne	67	7	,	,	,
cord-006460-3ayc0hne	67	8	the	the	DT
cord-006460-3ayc0hne	67	9	autopsy	autopsy	JJ
cord-006460-3ayc0hne	67	10	indicated	indicate	VBD
cord-006460-3ayc0hne	67	11	bronchopneumonia	bronchopneumonia	NN
cord-006460-3ayc0hne	67	12	,	,	,
cord-006460-3ayc0hne	67	13	necrotizing	necrotize	VBG
cord-006460-3ayc0hne	67	14	bacterial	bacterial	JJ
cord-006460-3ayc0hne	67	15	arteritis	arteritis	NN
cord-006460-3ayc0hne	67	16	,	,	,
cord-006460-3ayc0hne	67	17	hyaline	hyaline	JJ
cord-006460-3ayc0hne	67	18	membranes	membrane	NNS
cord-006460-3ayc0hne	67	19	in	in	IN
cord-006460-3ayc0hne	67	20	the	the	DT
cord-006460-3ayc0hne	67	21	lung	lung	NN
cord-006460-3ayc0hne	67	22	,	,	,
cord-006460-3ayc0hne	67	23	healed	heal	VBN
cord-006460-3ayc0hne	67	24	and	and	CC
cord-006460-3ayc0hne	67	25	acute	acute	JJ
cord-006460-3ayc0hne	67	26	renal	renal	JJ
cord-006460-3ayc0hne	67	27	infarcts	infarct	NNS
cord-006460-3ayc0hne	67	28	and	and	CC
cord-006460-3ayc0hne	67	29	acute	acute	JJ
cord-006460-3ayc0hne	67	30	tubular	tubular	JJ
cord-006460-3ayc0hne	67	31	necrosis	necrosis	NN
cord-006460-3ayc0hne	67	32	in	in	IN
cord-006460-3ayc0hne	67	33	the	the	DT
cord-006460-3ayc0hne	67	34	kidneys	kidney	NNS
cord-006460-3ayc0hne	67	35	,	,	,
cord-006460-3ayc0hne	67	36	hemorrhagic	hemorrhagic	JJ
cord-006460-3ayc0hne	67	37	foci	foci	NN
cord-006460-3ayc0hne	67	38	in	in	IN
cord-006460-3ayc0hne	67	39	the	the	DT
cord-006460-3ayc0hne	67	40	gut	gut	NN
cord-006460-3ayc0hne	67	41	,	,	,
cord-006460-3ayc0hne	67	42	pseudomembranous	pseudomembranous	JJ
cord-006460-3ayc0hne	67	43	enterocolitis	enterocolitis	NN
cord-006460-3ayc0hne	67	44	in	in	IN
cord-006460-3ayc0hne	67	45	the	the	DT
cord-006460-3ayc0hne	67	46	colon	colon	NN
cord-006460-3ayc0hne	67	47	,	,	,
cord-006460-3ayc0hne	67	48	and	and	CC
cord-006460-3ayc0hne	67	49	massive	massive	JJ
cord-006460-3ayc0hne	67	50	acute	acute	JJ
cord-006460-3ayc0hne	67	51	central	central	JJ
cord-006460-3ayc0hne	67	52	lobular	lobular	JJ
cord-006460-3ayc0hne	67	53	necrosis	necrosis	NN
cord-006460-3ayc0hne	67	54	of	of	IN
cord-006460-3ayc0hne	67	55	the	the	DT
cord-006460-3ayc0hne	67	56	liver	liver	NN
cord-006460-3ayc0hne	67	57	.	.	.
cord-006460-3ayc0hne	68	1	Thus	thus	RB
cord-006460-3ayc0hne	68	2	,	,	,
cord-006460-3ayc0hne	68	3	in	in	IN
cord-006460-3ayc0hne	68	4	this	this	DT
cord-006460-3ayc0hne	68	5	patient	patient	NN
cord-006460-3ayc0hne	68	6	there	there	EX
cord-006460-3ayc0hne	68	7	was	be	VBD
cord-006460-3ayc0hne	68	8	pathologic	pathologic	JJ
cord-006460-3ayc0hne	68	9	evidence	evidence	NN
cord-006460-3ayc0hne	68	10	of	of	IN
cord-006460-3ayc0hne	68	11	severe	severe	JJ
cord-006460-3ayc0hne	68	12	multiple	multiple	JJ
cord-006460-3ayc0hne	68	13	organ	organ	NN
cord-006460-3ayc0hne	68	14	dysfunction	dysfunction	NN
cord-006460-3ayc0hne	68	15	and/or	and/or	CC
cord-006460-3ayc0hne	68	16	failure	failure	NN
cord-006460-3ayc0hne	68	17	.	.	.
cord-006460-3ayc0hne	69	1	This	this	DT
cord-006460-3ayc0hne	69	2	led	lead	VBD
cord-006460-3ayc0hne	69	3	to	to	IN
cord-006460-3ayc0hne	69	4	the	the	DT
cord-006460-3ayc0hne	69	5	development	development	NN
cord-006460-3ayc0hne	69	6	of	of	IN
cord-006460-3ayc0hne	69	7	the	the	DT
cord-006460-3ayc0hne	69	8	concept	concept	NN
cord-006460-3ayc0hne	69	9	of	of	IN
cord-006460-3ayc0hne	69	10	MOF	MOF	NNP
cord-006460-3ayc0hne	69	11	.	.	.
cord-006460-3ayc0hne	70	1	During	during	IN
cord-006460-3ayc0hne	70	2	a	a	DT
cord-006460-3ayc0hne	70	3	sabbatical	sabbatical	NN
cord-006460-3ayc0hne	70	4	in	in	IN
cord-006460-3ayc0hne	70	5	Munich	Munich	NNP
cord-006460-3ayc0hne	70	6	,	,	,
cord-006460-3ayc0hne	70	7	Germany	Germany	NNP
cord-006460-3ayc0hne	70	8	,	,	,
cord-006460-3ayc0hne	70	9	I	-PRON-	PRP
cord-006460-3ayc0hne	70	10	worked	work	VBD
cord-006460-3ayc0hne	70	11	with	with	IN
cord-006460-3ayc0hne	70	12	Dr	Dr	NNP
cord-006460-3ayc0hne	70	13	Eugen	Eugen	NNP
cord-006460-3ayc0hne	70	14	Faist	Faist	NNP
cord-006460-3ayc0hne	70	15	.	.	.
cord-006460-3ayc0hne	71	1	Together	together	RB
cord-006460-3ayc0hne	71	2	we	-PRON-	PRP
cord-006460-3ayc0hne	71	3	reviewed	review	VBD
cord-006460-3ayc0hne	71	4	the	the	DT
cord-006460-3ayc0hne	71	5	experience	experience	NN
cord-006460-3ayc0hne	71	6	at	at	IN
cord-006460-3ayc0hne	71	7	the	the	DT
cord-006460-3ayc0hne	71	8	Klinikum	Klinikum	NNP
cord-006460-3ayc0hne	71	9	Grosshadern	Grosshadern	NNP
cord-006460-3ayc0hne	71	10	,	,	,
cord-006460-3ayc0hne	71	11	Ludwigs	Ludwigs	NNP
cord-006460-3ayc0hne	71	12	Maximillians	Maximillians	NNP
cord-006460-3ayc0hne	71	13	Universität	Universität	NNP
cord-006460-3ayc0hne	71	14	of	of	IN
cord-006460-3ayc0hne	71	15	the	the	DT
cord-006460-3ayc0hne	71	16	problem	problem	NN
cord-006460-3ayc0hne	71	17	of	of	IN
cord-006460-3ayc0hne	71	18	MOF	MOF	NNP
cord-006460-3ayc0hne	71	19	after	after	IN
cord-006460-3ayc0hne	71	20	injury	injury	NN
cord-006460-3ayc0hne	71	21	.	.	.
cord-006460-3ayc0hne	72	1	This	this	DT
cord-006460-3ayc0hne	72	2	was	be	VBD
cord-006460-3ayc0hne	72	3	reported	report	VBN
cord-006460-3ayc0hne	72	4	by	by	IN
cord-006460-3ayc0hne	72	5	Faist	Faist	NNP
cord-006460-3ayc0hne	72	6	at	at	IN
cord-006460-3ayc0hne	72	7	a	a	DT
cord-006460-3ayc0hne	72	8	meeting	meeting	NN
cord-006460-3ayc0hne	72	9	of	of	IN
cord-006460-3ayc0hne	72	10	the	the	DT
cord-006460-3ayc0hne	72	11	American	American	NNP
cord-006460-3ayc0hne	72	12	Association	Association	NNP
cord-006460-3ayc0hne	72	13	for	for	IN
cord-006460-3ayc0hne	72	14	the	the	DT
cord-006460-3ayc0hne	72	15	Surgery	Surgery	NNP
cord-006460-3ayc0hne	72	16	of	of	IN
cord-006460-3ayc0hne	72	17	Trauma	Trauma	NNP
cord-006460-3ayc0hne	72	18	in	in	IN
cord-006460-3ayc0hne	72	19	Colorado	Colorado	NNP
cord-006460-3ayc0hne	72	20	Springs	Springs	NNP
cord-006460-3ayc0hne	72	21	,	,	,
cord-006460-3ayc0hne	72	22	USA	USA	NNP
cord-006460-3ayc0hne	72	23	[	[	-LRB-
cord-006460-3ayc0hne	72	24	9	9	CD
cord-006460-3ayc0hne	72	25	]	]	-RRB-
cord-006460-3ayc0hne	72	26	.	.	.
cord-006460-3ayc0hne	73	1	In	in	IN
cord-006460-3ayc0hne	73	2	433	433	CD
cord-006460-3ayc0hne	73	3	consecutive	consecutive	JJ
cord-006460-3ayc0hne	73	4	patients	patient	NNS
cord-006460-3ayc0hne	73	5	with	with	IN
cord-006460-3ayc0hne	73	6	multiple	multiple	JJ
cord-006460-3ayc0hne	73	7	injuries	injury	NNS
cord-006460-3ayc0hne	73	8	,	,	,
cord-006460-3ayc0hne	73	9	50	50	CD
cord-006460-3ayc0hne	73	10	patients	patient	NNS
cord-006460-3ayc0hne	73	11	had	have	VBD
cord-006460-3ayc0hne	73	12	single	single	JJ
cord-006460-3ayc0hne	73	13	organ	organ	NN
cord-006460-3ayc0hne	73	14	failure	failure	NN
cord-006460-3ayc0hne	73	15	(	(	-LRB-
cord-006460-3ayc0hne	73	16	SOF	SOF	NNP
cord-006460-3ayc0hne	73	17	)	)	-RRB-
cord-006460-3ayc0hne	73	18	and	and	CC
cord-006460-3ayc0hne	73	19	34	34	CD
cord-006460-3ayc0hne	73	20	had	have	VBD
cord-006460-3ayc0hne	73	21	MOF	MOF	NNP
cord-006460-3ayc0hne	73	22	.	.	.
cord-006460-3ayc0hne	74	1	Mortality	mortality	NN
cord-006460-3ayc0hne	74	2	for	for	IN
cord-006460-3ayc0hne	74	3	MOF	MOF	NNP
cord-006460-3ayc0hne	74	4	patients	patient	NNS
cord-006460-3ayc0hne	74	5	was	be	VBD
cord-006460-3ayc0hne	74	6	56	56	CD
cord-006460-3ayc0hne	74	7	%	%	NN
cord-006460-3ayc0hne	74	8	.	.	.
cord-006460-3ayc0hne	75	1	There	there	EX
cord-006460-3ayc0hne	75	2	were	be	VBD
cord-006460-3ayc0hne	75	3	78	78	CD
cord-006460-3ayc0hne	75	4	deaths	death	NNS
cord-006460-3ayc0hne	75	5	overall	overall	JJ
cord-006460-3ayc0hne	75	6	(	(	-LRB-
cord-006460-3ayc0hne	75	7	18	18	CD
cord-006460-3ayc0hne	75	8	%	%	NN
cord-006460-3ayc0hne	75	9	)	)	-RRB-
cord-006460-3ayc0hne	75	10	.	.	.
cord-006460-3ayc0hne	76	1	Faist	Faist	NNP
cord-006460-3ayc0hne	76	2	described	describe	VBD
cord-006460-3ayc0hne	76	3	two	two	CD
cord-006460-3ayc0hne	76	4	patterns	pattern	NNS
cord-006460-3ayc0hne	76	5	:	:	:
cord-006460-3ayc0hne	76	6	a	a	DT
cord-006460-3ayc0hne	76	7	rapid	rapid	JJ
cord-006460-3ayc0hne	76	8	single	single	JJ
cord-006460-3ayc0hne	76	9	-	-	HYPH
cord-006460-3ayc0hne	76	10	phase	phase	NN
cord-006460-3ayc0hne	76	11	pattern	pattern	NN
cord-006460-3ayc0hne	76	12	of	of	IN
cord-006460-3ayc0hne	76	13	development	development	NN
cord-006460-3ayc0hne	76	14	of	of	IN
cord-006460-3ayc0hne	76	15	MOF	MOF	NNP
cord-006460-3ayc0hne	76	16	due	due	JJ
cord-006460-3ayc0hne	76	17	to	to	IN
cord-006460-3ayc0hne	76	18	trauma	trauma	NN
cord-006460-3ayc0hne	76	19	and	and	CC
cord-006460-3ayc0hne	76	20	shock	shock	NN
cord-006460-3ayc0hne	76	21	;	;	:
cord-006460-3ayc0hne	76	22	and	and	CC
cord-006460-3ayc0hne	76	23	a	a	DT
cord-006460-3ayc0hne	76	24	delayed	delay	VBN
cord-006460-3ayc0hne	76	25	second	second	JJ
cord-006460-3ayc0hne	76	26	-	-	HYPH
cord-006460-3ayc0hne	76	27	phase	phase	NN
cord-006460-3ayc0hne	76	28	MOF	MOF	NNP
cord-006460-3ayc0hne	76	29	due	due	JJ
cord-006460-3ayc0hne	76	30	to	to	IN
cord-006460-3ayc0hne	76	31	trauma	trauma	NN
cord-006460-3ayc0hne	76	32	,	,	,
cord-006460-3ayc0hne	76	33	shock	shock	NN
cord-006460-3ayc0hne	76	34	and	and	CC
cord-006460-3ayc0hne	76	35	then	then	RB
cord-006460-3ayc0hne	76	36	sepsis	sepsis	NN
cord-006460-3ayc0hne	76	37	.	.	.
cord-006460-3ayc0hne	77	1	The	the	DT
cord-006460-3ayc0hne	77	2	temporal	temporal	JJ
cord-006460-3ayc0hne	77	3	sequence	sequence	NN
cord-006460-3ayc0hne	77	4	of	of	IN
cord-006460-3ayc0hne	77	5	events	event	NNS
cord-006460-3ayc0hne	77	6	of	of	IN
cord-006460-3ayc0hne	77	7	organ	organ	NN
cord-006460-3ayc0hne	77	8	failure	failure	NN
cord-006460-3ayc0hne	77	9	was	be	VBD
cord-006460-3ayc0hne	77	10	the	the	DT
cord-006460-3ayc0hne	77	11	lung	lung	NN
cord-006460-3ayc0hne	77	12	first	first	RB
cord-006460-3ayc0hne	77	13	,	,	,
cord-006460-3ayc0hne	77	14	then	then	RB
cord-006460-3ayc0hne	77	15	the	the	DT
cord-006460-3ayc0hne	77	16	clotting	clotting	NN
cord-006460-3ayc0hne	77	17	system	system	NN
cord-006460-3ayc0hne	77	18	,	,	,
cord-006460-3ayc0hne	77	19	the	the	DT
cord-006460-3ayc0hne	77	20	kidney	kidney	NN
cord-006460-3ayc0hne	77	21	and	and	CC
cord-006460-3ayc0hne	77	22	the	the	DT
cord-006460-3ayc0hne	77	23	liver	liver	NN
cord-006460-3ayc0hne	77	24	,	,	,
cord-006460-3ayc0hne	77	25	with	with	IN
cord-006460-3ayc0hne	77	26	sepsis	sepsis	NN
cord-006460-3ayc0hne	77	27	ultimately	ultimately	RB
cord-006460-3ayc0hne	77	28	being	be	VBG
cord-006460-3ayc0hne	77	29	the	the	DT
cord-006460-3ayc0hne	77	30	cause	cause	NN
cord-006460-3ayc0hne	77	31	of	of	IN
cord-006460-3ayc0hne	77	32	death	death	NN
cord-006460-3ayc0hne	77	33	in	in	IN
cord-006460-3ayc0hne	77	34	a	a	DT
cord-006460-3ayc0hne	77	35	number	number	NN
cord-006460-3ayc0hne	77	36	of	of	IN
cord-006460-3ayc0hne	77	37	patients	patient	NNS
cord-006460-3ayc0hne	77	38	.	.	.
cord-006460-3ayc0hne	78	1	Definitions	definition	NNS
cord-006460-3ayc0hne	78	2	of	of	IN
cord-006460-3ayc0hne	78	3	failure	failure	NN
cord-006460-3ayc0hne	78	4	of	of	IN
cord-006460-3ayc0hne	78	5	each	each	DT
cord-006460-3ayc0hne	78	6	organ	organ	NN
cord-006460-3ayc0hne	78	7	system	system	NN
cord-006460-3ayc0hne	78	8	were	be	VBD
cord-006460-3ayc0hne	78	9	also	also	RB
cord-006460-3ayc0hne	78	10	given	give	VBN
cord-006460-3ayc0hne	78	11	.	.	.
cord-006460-3ayc0hne	79	1	For	for	IN
cord-006460-3ayc0hne	79	2	example	example	NN
cord-006460-3ayc0hne	79	3	,	,	,
cord-006460-3ayc0hne	79	4	cardiovascular	cardiovascular	JJ
cord-006460-3ayc0hne	79	5	failure	failure	NN
cord-006460-3ayc0hne	79	6	was	be	VBD
cord-006460-3ayc0hne	79	7	defined	define	VBN
cord-006460-3ayc0hne	79	8	as	as	IN
cord-006460-3ayc0hne	79	9	the	the	DT
cord-006460-3ayc0hne	79	10	presence	presence	NN
cord-006460-3ayc0hne	79	11	of	of	IN
cord-006460-3ayc0hne	79	12	one	one	CD
cord-006460-3ayc0hne	79	13	or	or	CC
cord-006460-3ayc0hne	79	14	more	more	JJR
cord-006460-3ayc0hne	79	15	of	of	IN
cord-006460-3ayc0hne	79	16	the	the	DT
cord-006460-3ayc0hne	79	17	following	following	NN
cord-006460-3ayc0hne	79	18	:	:	:
cord-006460-3ayc0hne	79	19	(	(	-LRB-
cord-006460-3ayc0hne	79	20	a	a	LS
cord-006460-3ayc0hne	79	21	)	)	-RRB-
cord-006460-3ayc0hne	79	22	a	a	DT
cord-006460-3ayc0hne	79	23	heart	heart	NN
cord-006460-3ayc0hne	79	24	rate	rate	NN
cord-006460-3ayc0hne	79	25	of	of	IN
cord-006460-3ayc0hne	79	26	<	<	NNP
cord-006460-3ayc0hne	79	27	54	54	CD
cord-006460-3ayc0hne	79	28	/	/	SYM
cord-006460-3ayc0hne	79	29	min	min	NN
cord-006460-3ayc0hne	80	1	;	;	:
cord-006460-3ayc0hne	80	2	(	(	-LRB-
cord-006460-3ayc0hne	80	3	b	b	NN
cord-006460-3ayc0hne	80	4	)	)	-RRB-
cord-006460-3ayc0hne	80	5	mean	mean	VB
cord-006460-3ayc0hne	80	6	arterial	arterial	JJ
cord-006460-3ayc0hne	80	7	pressure	pressure	NN
cord-006460-3ayc0hne	80	8	of	of	IN
cord-006460-3ayc0hne	80	9	<	<	NNP
cord-006460-3ayc0hne	80	10	49	49	CD
cord-006460-3ayc0hne	80	11	mmHg	mmHg	NNS
cord-006460-3ayc0hne	80	12	;	;	,
cord-006460-3ayc0hne	80	13	(	(	-LRB-
cord-006460-3ayc0hne	80	14	c	c	NN
cord-006460-3ayc0hne	80	15	)	)	-RRB-
cord-006460-3ayc0hne	80	16	occurrence	occurrence	NN
cord-006460-3ayc0hne	80	17	of	of	IN
cord-006460-3ayc0hne	80	18	ventricular	ventricular	JJ
cord-006460-3ayc0hne	80	19	tachycardia	tachycardia	NN
cord-006460-3ayc0hne	80	20	and/or	and/or	CC
cord-006460-3ayc0hne	80	21	ventricular	ventricular	JJ
cord-006460-3ayc0hne	80	22	fibrillation	fibrillation	NN
cord-006460-3ayc0hne	80	23	;	;	:
cord-006460-3ayc0hne	81	1	(	(	-LRB-
cord-006460-3ayc0hne	81	2	d	d	NN
cord-006460-3ayc0hne	81	3	)	)	-RRB-
cord-006460-3ayc0hne	81	4	pH<7.24	ph<7.24	CD
cord-006460-3ayc0hne	81	5	with	with	IN
cord-006460-3ayc0hne	81	6	a	a	DT
cord-006460-3ayc0hne	81	7	PaCO	paco	NN
cord-006460-3ayc0hne	81	8	2	2	CD
cord-006460-3ayc0hne	81	9	of	of	IN
cord-006460-3ayc0hne	81	10	<	<	NNP
cord-006460-3ayc0hne	81	11	49	49	CD
cord-006460-3ayc0hne	81	12	mmHg	mmHg	NNS
cord-006460-3ayc0hne	81	13	.	.	.
cord-006460-3ayc0hne	82	1	Respiratory	respiratory	JJ
cord-006460-3ayc0hne	82	2	failure	failure	NN
cord-006460-3ayc0hne	82	3	was	be	VBD
cord-006460-3ayc0hne	82	4	described	describe	VBN
cord-006460-3ayc0hne	82	5	as	as	IN
cord-006460-3ayc0hne	82	6	one	one	CD
cord-006460-3ayc0hne	82	7	or	or	CC
cord-006460-3ayc0hne	82	8	more	more	JJR
cord-006460-3ayc0hne	82	9	of	of	IN
cord-006460-3ayc0hne	82	10	the	the	DT
cord-006460-3ayc0hne	82	11	following	following	NN
cord-006460-3ayc0hne	82	12	:	:	:
cord-006460-3ayc0hne	82	13	(	(	-LRB-
cord-006460-3ayc0hne	82	14	a	a	LS
cord-006460-3ayc0hne	82	15	)	)	-RRB-
cord-006460-3ayc0hne	82	16	a	a	DT
cord-006460-3ayc0hne	82	17	respiratory	respiratory	JJ
cord-006460-3ayc0hne	82	18	rate	rate	NN
cord-006460-3ayc0hne	82	19	of	of	IN
cord-006460-3ayc0hne	82	20	<	<	NNP
cord-006460-3ayc0hne	82	21	5	5	CD
cord-006460-3ayc0hne	82	22	or	or	CC
cord-006460-3ayc0hne	82	23	>	>	XX
cord-006460-3ayc0hne	82	24	49	49	CD
cord-006460-3ayc0hne	82	25	/	/	SYM
cord-006460-3ayc0hne	82	26	min	min	NN
cord-006460-3ayc0hne	82	27	;	;	:
cord-006460-3ayc0hne	82	28	(	(	-LRB-
cord-006460-3ayc0hne	82	29	b	b	NN
cord-006460-3ayc0hne	82	30	)	)	-RRB-
cord-006460-3ayc0hne	82	31	PaCO	paco	NN
cord-006460-3ayc0hne	82	32	2	2	CD
cord-006460-3ayc0hne	82	33	>	>	SYM
cord-006460-3ayc0hne	82	34	50	50	CD
cord-006460-3ayc0hne	82	35	mmHg	mmHg	NNS
cord-006460-3ayc0hne	82	36	;	;	,
cord-006460-3ayc0hne	82	37	(	(	-LRB-
cord-006460-3ayc0hne	82	38	c	c	NN
cord-006460-3ayc0hne	82	39	)	)	-RRB-
cord-006460-3ayc0hne	83	1	A	a	DT
cord-006460-3ayc0hne	83	2	a	a	DT
cord-006460-3ayc0hne	83	3	PO	po	NN
cord-006460-3ayc0hne	83	4	2	2	CD
cord-006460-3ayc0hne	83	5	>	>	SYM
cord-006460-3ayc0hne	83	6	350	350	CD
cord-006460-3ayc0hne	83	7	mmHg	mmHg	NNS
cord-006460-3ayc0hne	83	8	,	,	,
cord-006460-3ayc0hne	83	9	FiO	fio	NN
cord-006460-3ayc0hne	83	10	2	2	CD
cord-006460-3ayc0hne	83	11	>	>	SYM
cord-006460-3ayc0hne	83	12	0.40	0.40	CD
cord-006460-3ayc0hne	83	13	,	,	,
cord-006460-3ayc0hne	83	14	positive	positive	JJ
cord-006460-3ayc0hne	83	15	end	end	NN
cord-006460-3ayc0hne	83	16	-	-	HYPH
cord-006460-3ayc0hne	83	17	expiratory	expiratory	NN
cord-006460-3ayc0hne	83	18	pressure	pressure	NN
cord-006460-3ayc0hne	83	19	(	(	-LRB-
cord-006460-3ayc0hne	83	20	PEEP	peep	NN
cord-006460-3ayc0hne	83	21	)	)	-RRB-
cord-006460-3ayc0hne	84	1	>	>	XX
cord-006460-3ayc0hne	85	1	5	5	LS
cord-006460-3ayc0hne	85	2	;	;	:
cord-006460-3ayc0hne	85	3	(	(	-LRB-
cord-006460-3ayc0hne	85	4	d	d	NN
cord-006460-3ayc0hne	85	5	)	)	-RRB-
cord-006460-3ayc0hne	85	6	dependence	dependence	NN
cord-006460-3ayc0hne	85	7	on	on	IN
cord-006460-3ayc0hne	85	8	a	a	DT
cord-006460-3ayc0hne	85	9	ventilator	ventilator	NN
cord-006460-3ayc0hne	85	10	on	on	IN
cord-006460-3ayc0hne	85	11	the	the	DT
cord-006460-3ayc0hne	85	12	fourth	fourth	JJ
cord-006460-3ayc0hne	85	13	day	day	NN
cord-006460-3ayc0hne	85	14	of	of	IN
cord-006460-3ayc0hne	85	15	organ	organ	NN
cord-006460-3ayc0hne	85	16	system	system	NN
cord-006460-3ayc0hne	85	17	failure	failure	NN
cord-006460-3ayc0hne	85	18	.	.	.
cord-006460-3ayc0hne	86	1	In	in	IN
cord-006460-3ayc0hne	86	2	the	the	DT
cord-006460-3ayc0hne	86	3	same	same	JJ
cord-006460-3ayc0hne	86	4	way	way	NN
cord-006460-3ayc0hne	86	5	,	,	,
cord-006460-3ayc0hne	86	6	failure	failure	NN
cord-006460-3ayc0hne	86	7	of	of	IN
cord-006460-3ayc0hne	86	8	all	all	DT
cord-006460-3ayc0hne	86	9	organs	organ	NNS
cord-006460-3ayc0hne	86	10	and	and	CC
cord-006460-3ayc0hne	86	11	systems	system	NNS
cord-006460-3ayc0hne	86	12	-the	-the	DT
cord-006460-3ayc0hne	86	13	kidney	kidney	NN
cord-006460-3ayc0hne	86	14	,	,	,
cord-006460-3ayc0hne	86	15	liver	liver	NN
cord-006460-3ayc0hne	86	16	,	,	,
cord-006460-3ayc0hne	86	17	gastrointestinal	gastrointestinal	JJ
cord-006460-3ayc0hne	86	18	tract	tract	NN
cord-006460-3ayc0hne	86	19	,	,	,
cord-006460-3ayc0hne	86	20	nervous	nervous	JJ
cord-006460-3ayc0hne	86	21	system	system	NN
cord-006460-3ayc0hne	86	22	,	,	,
cord-006460-3ayc0hne	86	23	etc	etc	FW
cord-006460-3ayc0hne	86	24	.	.	.
cord-006460-3ayc0hne	87	1	-were	-were	RBR
cord-006460-3ayc0hne	87	2	defined	define	VBN
cord-006460-3ayc0hne	87	3	.	.	.
cord-006460-3ayc0hne	88	1	These	these	DT
cord-006460-3ayc0hne	88	2	figures	figure	NNS
cord-006460-3ayc0hne	88	3	were	be	VBD
cord-006460-3ayc0hne	88	4	also	also	RB
cord-006460-3ayc0hne	88	5	updated	update	VBN
cord-006460-3ayc0hne	88	6	and	and	CC
cord-006460-3ayc0hne	88	7	reported	report	VBN
cord-006460-3ayc0hne	88	8	by	by	IN
cord-006460-3ayc0hne	88	9	Faist	Faist	NNP
cord-006460-3ayc0hne	88	10	et	et	FW
cord-006460-3ayc0hne	88	11	al	al	NNP
cord-006460-3ayc0hne	88	12	.	.	.
cord-006460-3ayc0hne	89	1	[	[	-LRB-
cord-006460-3ayc0hne	89	2	10	10	CD
cord-006460-3ayc0hne	89	3	]	]	-RRB-
cord-006460-3ayc0hne	89	4	in	in	IN
cord-006460-3ayc0hne	89	5	the	the	DT
cord-006460-3ayc0hne	89	6	German	german	JJ
cord-006460-3ayc0hne	89	7	literature	literature	NN
cord-006460-3ayc0hne	89	8	.	.	.
cord-006460-3ayc0hne	90	1	Following	follow	VBG
cord-006460-3ayc0hne	90	2	this	this	DT
cord-006460-3ayc0hne	90	3	presentation	presentation	NN
cord-006460-3ayc0hne	90	4	,	,	,
cord-006460-3ayc0hne	90	5	many	many	JJ
cord-006460-3ayc0hne	90	6	joined	join	VBD
cord-006460-3ayc0hne	90	7	in	in	IN
cord-006460-3ayc0hne	90	8	the	the	DT
cord-006460-3ayc0hne	90	9	battle	battle	NN
cord-006460-3ayc0hne	90	10	.	.	.
cord-006460-3ayc0hne	91	1	Beale	Beale	NNP
cord-006460-3ayc0hne	91	2	and	and	CC
cord-006460-3ayc0hne	91	3	Bihari	Bihari	NNP
cord-006460-3ayc0hne	91	4	[	[	-LRB-
cord-006460-3ayc0hne	91	5	11	11	CD
cord-006460-3ayc0hne	91	6	]	]	-RRB-
cord-006460-3ayc0hne	91	7	stated	state	VBD
cord-006460-3ayc0hne	91	8	that	that	IN
cord-006460-3ayc0hne	91	9	"	"	``
cord-006460-3ayc0hne	91	10	the	the	DT
cord-006460-3ayc0hne	91	11	search	search	NN
cord-006460-3ayc0hne	91	12	for	for	IN
cord-006460-3ayc0hne	91	13	a	a	DT
cord-006460-3ayc0hne	91	14	unifying	unifying	JJ
cord-006460-3ayc0hne	91	15	mechanism	mechanism	NN
cord-006460-3ayc0hne	91	16	and	and	CC
cord-006460-3ayc0hne	91	17	,	,	,
cord-006460-3ayc0hne	91	18	hence	hence	RB
cord-006460-3ayc0hne	91	19	,	,	,
cord-006460-3ayc0hne	91	20	perhaps	perhaps	RB
cord-006460-3ayc0hne	91	21	an	an	DT
cord-006460-3ayc0hne	91	22	effective	effective	JJ
cord-006460-3ayc0hne	91	23	therapy	therapy	NN
cord-006460-3ayc0hne	91	24	for	for	IN
cord-006460-3ayc0hne	91	25	MOF	MOF	NNP
cord-006460-3ayc0hne	91	26	has	have	VBZ
cord-006460-3ayc0hne	91	27	been	be	VBN
cord-006460-3ayc0hne	91	28	intense	intense	JJ
cord-006460-3ayc0hne	91	29	.	.	.
cord-006460-3ayc0hne	92	1	"	"	''
cord-006460-3ayc0hne	93	1	I	-PRON-	PRP
cord-006460-3ayc0hne	93	2	reviewed	review	VBD
cord-006460-3ayc0hne	93	3	our	-PRON-	PRP$
cord-006460-3ayc0hne	93	4	experience	experience	NN
cord-006460-3ayc0hne	93	5	with	with	IN
cord-006460-3ayc0hne	93	6	MOF	MOF	NNP
cord-006460-3ayc0hne	93	7	at	at	IN
cord-006460-3ayc0hne	93	8	St.	St.	NNP
cord-006460-3ayc0hne	93	9	Louis	Louis	NNP
cord-006460-3ayc0hne	93	10	University	University	NNP
cord-006460-3ayc0hne	93	11	in	in	IN
cord-006460-3ayc0hne	93	12	almost	almost	RB
cord-006460-3ayc0hne	93	13	6000	6000	CD
cord-006460-3ayc0hne	93	14	patients	patient	NNS
cord-006460-3ayc0hne	93	15	who	who	WP
cord-006460-3ayc0hne	93	16	underwent	undergo	VBD
cord-006460-3ayc0hne	93	17	cardiac	cardiac	JJ
cord-006460-3ayc0hne	93	18	operations	operation	NNS
cord-006460-3ayc0hne	93	19	over	over	IN
cord-006460-3ayc0hne	93	20	several	several	JJ
cord-006460-3ayc0hne	93	21	years	year	NNS
cord-006460-3ayc0hne	93	22	[	[	-LRB-
cord-006460-3ayc0hne	93	23	12	12	CD
cord-006460-3ayc0hne	93	24	]	]	-RRB-
cord-006460-3ayc0hne	93	25	.	.	.
cord-006460-3ayc0hne	94	1	MOF	MOF	NNP
cord-006460-3ayc0hne	94	2	occurred	occur	VBD
cord-006460-3ayc0hne	94	3	in	in	IN
cord-006460-3ayc0hne	94	4	128	128	CD
cord-006460-3ayc0hne	94	5	patients	patient	NNS
cord-006460-3ayc0hne	94	6	(	(	-LRB-
cord-006460-3ayc0hne	94	7	2.1	2.1	CD
cord-006460-3ayc0hne	94	8	%	%	NN
cord-006460-3ayc0hne	94	9	)	)	-RRB-
cord-006460-3ayc0hne	94	10	,	,	,
cord-006460-3ayc0hne	94	11	primarily	primarily	RB
cord-006460-3ayc0hne	94	12	after	after	IN
cord-006460-3ayc0hne	94	13	emergency	emergency	NN
cord-006460-3ayc0hne	94	14	operations	operation	NNS
cord-006460-3ayc0hne	94	15	and	and	CC
cord-006460-3ayc0hne	94	16	in	in	IN
cord-006460-3ayc0hne	94	17	high	high	JJ
cord-006460-3ayc0hne	94	18	-	-	HYPH
cord-006460-3ayc0hne	94	19	risk	risk	NN
cord-006460-3ayc0hne	94	20	patients	patient	NNS
cord-006460-3ayc0hne	94	21	.	.	.
cord-006460-3ayc0hne	95	1	However	however	RB
cord-006460-3ayc0hne	95	2	,	,	,
cord-006460-3ayc0hne	95	3	78	78	CD
cord-006460-3ayc0hne	95	4	%	%	NN
cord-006460-3ayc0hne	95	5	of	of	IN
cord-006460-3ayc0hne	95	6	these	these	DT
cord-006460-3ayc0hne	95	7	MOF	MOF	NNP
cord-006460-3ayc0hne	95	8	patients	patient	NNS
cord-006460-3ayc0hne	95	9	died	die	VBD
cord-006460-3ayc0hne	95	10	.	.	.
cord-006460-3ayc0hne	96	1	Mortality	mortality	NN
cord-006460-3ayc0hne	96	2	in	in	IN
cord-006460-3ayc0hne	96	3	all	all	DT
cord-006460-3ayc0hne	96	4	patients	patient	NNS
cord-006460-3ayc0hne	96	5	was	be	VBD
cord-006460-3ayc0hne	96	6	4.7	4.7	CD
cord-006460-3ayc0hne	96	7	%	%	NN
cord-006460-3ayc0hne	96	8	.	.	.
cord-006460-3ayc0hne	97	1	Thus	thus	RB
cord-006460-3ayc0hne	97	2	,	,	,
cord-006460-3ayc0hne	97	3	most	most	JJS
cord-006460-3ayc0hne	97	4	were	be	VBD
cord-006460-3ayc0hne	97	5	elective	elective	JJ
cord-006460-3ayc0hne	97	6	cardiac	cardiac	JJ
cord-006460-3ayc0hne	97	7	surgical	surgical	JJ
cord-006460-3ayc0hne	97	8	procedures	procedure	NNS
cord-006460-3ayc0hne	97	9	and	and	CC
cord-006460-3ayc0hne	97	10	the	the	DT
cord-006460-3ayc0hne	97	11	risk	risk	NN
cord-006460-3ayc0hne	97	12	was	be	VBD
cord-006460-3ayc0hne	97	13	low	low	JJ
cord-006460-3ayc0hne	97	14	.	.	.
cord-006460-3ayc0hne	98	1	Recently	recently	RB
cord-006460-3ayc0hne	98	2	,	,	,
cord-006460-3ayc0hne	98	3	a	a	DT
cord-006460-3ayc0hne	98	4	new	new	JJ
cord-006460-3ayc0hne	98	5	proposal	proposal	NN
cord-006460-3ayc0hne	98	6	was	be	VBD
cord-006460-3ayc0hne	98	7	developed	develop	VBN
cord-006460-3ayc0hne	98	8	by	by	IN
cord-006460-3ayc0hne	98	9	a	a	DT
cord-006460-3ayc0hne	98	10	consensus	consensus	NN
cord-006460-3ayc0hne	98	11	conference	conference	NN
cord-006460-3ayc0hne	98	12	of	of	IN
cord-006460-3ayc0hne	98	13	physicians	physician	NNS
cord-006460-3ayc0hne	98	14	,	,	,
cord-006460-3ayc0hne	98	15	intensivists	intensivists	NNP
cord-006460-3ayc0hne	98	16	and	and	CC
cord-006460-3ayc0hne	98	17	surgeons	surgeon	NNS
cord-006460-3ayc0hne	98	18	[	[	-LRB-
cord-006460-3ayc0hne	98	19	13	13	CD
cord-006460-3ayc0hne	98	20	]	]	-RRB-
cord-006460-3ayc0hne	98	21	.	.	.
cord-006460-3ayc0hne	99	1	They	-PRON-	PRP
cord-006460-3ayc0hne	99	2	defined	define	VBD
cord-006460-3ayc0hne	99	3	the	the	DT
cord-006460-3ayc0hne	99	4	concept	concept	NN
cord-006460-3ayc0hne	99	5	of	of	IN
cord-006460-3ayc0hne	99	6	SIRS	SIRS	NNP
cord-006460-3ayc0hne	99	7	and	and	CC
cord-006460-3ayc0hne	99	8	MODS	mod	NNS
cord-006460-3ayc0hne	99	9	.	.	.
cord-006460-3ayc0hne	100	1	SIRS	SIRS	NNP
cord-006460-3ayc0hne	100	2	is	be	VBZ
cord-006460-3ayc0hne	100	3	defined	define	VBN
cord-006460-3ayc0hne	100	4	as	as	IN
cord-006460-3ayc0hne	100	5	the	the	DT
cord-006460-3ayc0hne	100	6	response	response	NN
cord-006460-3ayc0hne	100	7	to	to	IN
cord-006460-3ayc0hne	100	8	a	a	DT
cord-006460-3ayc0hne	100	9	variety	variety	NN
cord-006460-3ayc0hne	100	10	of	of	IN
cord-006460-3ayc0hne	100	11	severe	severe	JJ
cord-006460-3ayc0hne	100	12	clinical	clinical	JJ
cord-006460-3ayc0hne	100	13	insults	insult	NNS
cord-006460-3ayc0hne	100	14	with	with	IN
cord-006460-3ayc0hne	100	15	two	two	CD
cord-006460-3ayc0hne	100	16	or	or	CC
cord-006460-3ayc0hne	100	17	more	more	JJR
cord-006460-3ayc0hne	100	18	of	of	IN
cord-006460-3ayc0hne	100	19	the	the	DT
cord-006460-3ayc0hne	100	20	following	follow	VBG
cord-006460-3ayc0hne	100	21	conditions	condition	NNS
cord-006460-3ayc0hne	100	22	:	:	:
cord-006460-3ayc0hne	100	23	a	a	DT
cord-006460-3ayc0hne	100	24	temperature	temperature	NN
cord-006460-3ayc0hne	100	25	>	>	XX
cord-006460-3ayc0hne	100	26	38	38	CD
cord-006460-3ayc0hne	100	27	or	or	CC
cord-006460-3ayc0hne	100	28	<	<	XX
cord-006460-3ayc0hne	100	29	36	36	CD
cord-006460-3ayc0hne	100	30	°	°	NN
cord-006460-3ayc0hne	100	31	C	c	NN
cord-006460-3ayc0hne	100	32	;	;	:
cord-006460-3ayc0hne	100	33	a	a	DT
cord-006460-3ayc0hne	100	34	heart	heart	NN
cord-006460-3ayc0hne	100	35	rate	rate	NN
cord-006460-3ayc0hne	100	36	>	>	XX
cord-006460-3ayc0hne	100	37	90	90	CD
cord-006460-3ayc0hne	100	38	beats	beat	NNS
cord-006460-3ayc0hne	100	39	/	/	SYM
cord-006460-3ayc0hne	100	40	min	min	NN
cord-006460-3ayc0hne	100	41	;	;	:
cord-006460-3ayc0hne	100	42	a	a	DT
cord-006460-3ayc0hne	100	43	respiratory	respiratory	JJ
cord-006460-3ayc0hne	100	44	rate	rate	NN
cord-006460-3ayc0hne	100	45	of	of	IN
cord-006460-3ayc0hne	100	46	>	>	$
cord-006460-3ayc0hne	100	47	20	20	CD
cord-006460-3ayc0hne	100	48	breaths	breath	NNS
cord-006460-3ayc0hne	100	49	/	/	SYM
cord-006460-3ayc0hne	100	50	min	min	NN
cord-006460-3ayc0hne	100	51	;	;	:
cord-006460-3ayc0hne	100	52	or	or	CC
cord-006460-3ayc0hne	100	53	a	a	DT
cord-006460-3ayc0hne	100	54	PaCO	paco	NN
cord-006460-3ayc0hne	100	55	2	2	CD
cord-006460-3ayc0hne	100	56	<	<	XX
cord-006460-3ayc0hne	100	57	32	32	CD
cord-006460-3ayc0hne	100	58	torr	torr	NN
cord-006460-3ayc0hne	100	59	(	(	-LRB-
cord-006460-3ayc0hne	100	60	<	<	NNP
cord-006460-3ayc0hne	100	61	4.3	4.3	CD
cord-006460-3ayc0hne	100	62	kPa	kPa	NNPS
cord-006460-3ayc0hne	100	63	)	)	-RRB-
cord-006460-3ayc0hne	100	64	or	or	CC
cord-006460-3ayc0hne	100	65	a	a	DT
cord-006460-3ayc0hne	100	66	white	white	JJ
cord-006460-3ayc0hne	100	67	blood	blood	NN
cord-006460-3ayc0hne	100	68	count	count	NN
cord-006460-3ayc0hne	100	69	of	of	IN
cord-006460-3ayc0hne	100	70	>	>	XX
cord-006460-3ayc0hne	100	71	12,000	12,000	CD
cord-006460-3ayc0hne	100	72	or	or	CC
cord-006460-3ayc0hne	100	73	<	<	XX
cord-006460-3ayc0hne	100	74	4000	4000	CD
cord-006460-3ayc0hne	100	75	cells	cell	NNS
cord-006460-3ayc0hne	100	76	/	/	SYM
cord-006460-3ayc0hne	100	77	mm	mm	NNP
cord-006460-3ayc0hne	100	78	3	3	CD
cord-006460-3ayc0hne	100	79	,	,	,
cord-006460-3ayc0hne	100	80	or	or	CC
cord-006460-3ayc0hne	100	81	>	>	XX
cord-006460-3ayc0hne	100	82	10	10	CD
cord-006460-3ayc0hne	100	83	%	%	NN
cord-006460-3ayc0hne	100	84	immature	immature	JJ
cord-006460-3ayc0hne	100	85	or	or	CC
cord-006460-3ayc0hne	100	86	band	band	NN
cord-006460-3ayc0hne	100	87	forms	form	NNS
cord-006460-3ayc0hne	100	88	.	.	.
cord-006460-3ayc0hne	101	1	MODS	MODS	NNP
cord-006460-3ayc0hne	101	2	was	be	VBD
cord-006460-3ayc0hne	101	3	described	describe	VBN
cord-006460-3ayc0hne	101	4	simply	simply	RB
cord-006460-3ayc0hne	101	5	as	as	IN
cord-006460-3ayc0hne	101	6	the	the	DT
cord-006460-3ayc0hne	101	7	presence	presence	NN
cord-006460-3ayc0hne	101	8	of	of	IN
cord-006460-3ayc0hne	101	9	altered	alter	VBN
cord-006460-3ayc0hne	101	10	organ	organ	NN
cord-006460-3ayc0hne	101	11	function	function	NN
cord-006460-3ayc0hne	101	12	in	in	IN
cord-006460-3ayc0hne	101	13	an	an	DT
cord-006460-3ayc0hne	101	14	acutely	acutely	RB
cord-006460-3ayc0hne	101	15	ill	ill	JJ
cord-006460-3ayc0hne	101	16	patient	patient	NN
cord-006460-3ayc0hne	101	17	such	such	PDT
cord-006460-3ayc0hne	101	18	that	that	DT
cord-006460-3ayc0hne	101	19	homeostasis	homeostasis	NN
cord-006460-3ayc0hne	101	20	can	can	MD
cord-006460-3ayc0hne	101	21	not	not	RB
cord-006460-3ayc0hne	101	22	be	be	VB
cord-006460-3ayc0hne	101	23	maintained	maintain	VBN
cord-006460-3ayc0hne	101	24	without	without	IN
cord-006460-3ayc0hne	101	25	intervention	intervention	NN
cord-006460-3ayc0hne	101	26	.	.	.
cord-006460-3ayc0hne	102	1	Since	since	IN
cord-006460-3ayc0hne	102	2	that	that	DT
cord-006460-3ayc0hne	102	3	time	time	NN
cord-006460-3ayc0hne	102	4	,	,	,
cord-006460-3ayc0hne	102	5	many	many	JJ
cord-006460-3ayc0hne	102	6	have	have	VBP
cord-006460-3ayc0hne	102	7	continued	continue	VBN
cord-006460-3ayc0hne	102	8	to	to	TO
cord-006460-3ayc0hne	102	9	use	use	VB
cord-006460-3ayc0hne	102	10	SIRS	SIRS	NNP
cord-006460-3ayc0hne	102	11	and	and	CC
cord-006460-3ayc0hne	102	12	MODS	mods	NN
cord-006460-3ayc0hne	102	13	as	as	IN
cord-006460-3ayc0hne	102	14	a	a	DT
cord-006460-3ayc0hne	102	15	concept	concept	NN
cord-006460-3ayc0hne	102	16	[	[	-LRB-
cord-006460-3ayc0hne	102	17	14	14	CD
cord-006460-3ayc0hne	102	18	,	,	,
cord-006460-3ayc0hne	102	19	15	15	CD
cord-006460-3ayc0hne	102	20	]	]	-RRB-
cord-006460-3ayc0hne	102	21	;	;	:
cord-006460-3ayc0hne	102	22	however	however	RB
cord-006460-3ayc0hne	102	23	,	,	,
cord-006460-3ayc0hne	102	24	this	this	DT
cord-006460-3ayc0hne	102	25	has	have	VBZ
cord-006460-3ayc0hne	102	26	been	be	VBN
cord-006460-3ayc0hne	102	27	criticized	criticize	VBN
cord-006460-3ayc0hne	102	28	by	by	IN
cord-006460-3ayc0hne	102	29	many	many	JJ
cord-006460-3ayc0hne	102	30	[	[	-LRB-
cord-006460-3ayc0hne	102	31	16	16	CD
cord-006460-3ayc0hne	102	32	]	]	-RRB-
cord-006460-3ayc0hne	102	33	,	,	,
cord-006460-3ayc0hne	102	34	including	include	VBG
cord-006460-3ayc0hne	102	35	myself	-PRON-	PRP
cord-006460-3ayc0hne	102	36	.	.	.
cord-006460-3ayc0hne	103	1	I	-PRON-	PRP
cord-006460-3ayc0hne	103	2	stated	state	VBD
cord-006460-3ayc0hne	103	3	then	then	RB
cord-006460-3ayc0hne	103	4	that	that	IN
cord-006460-3ayc0hne	103	5	"	"	``
cord-006460-3ayc0hne	103	6	our	-PRON-	PRP$
cord-006460-3ayc0hne	103	7	ingenuity	ingenuity	NN
cord-006460-3ayc0hne	103	8	in	in	IN
cord-006460-3ayc0hne	103	9	developing	develop	VBG
cord-006460-3ayc0hne	103	10	terminology	terminology	NN
cord-006460-3ayc0hne	103	11	exceeds	exceed	VBZ
cord-006460-3ayc0hne	103	12	our	-PRON-	PRP$
cord-006460-3ayc0hne	103	13	abilities	ability	NNS
cord-006460-3ayc0hne	103	14	to	to	TO
cord-006460-3ayc0hne	103	15	take	take	VB
cord-006460-3ayc0hne	103	16	care	care	NN
cord-006460-3ayc0hne	103	17	of	of	IN
cord-006460-3ayc0hne	103	18	these	these	DT
cord-006460-3ayc0hne	103	19	patients	patient	NNS
cord-006460-3ayc0hne	103	20	"	"	``
cord-006460-3ayc0hne	103	21	[	[	-LRB-
cord-006460-3ayc0hne	103	22	17	17	CD
cord-006460-3ayc0hne	103	23	]	]	-RRB-
cord-006460-3ayc0hne	103	24	.	.	.
cord-006460-3ayc0hne	104	1	For	for	IN
cord-006460-3ayc0hne	104	2	example	example	NN
cord-006460-3ayc0hne	104	3	,	,	,
cord-006460-3ayc0hne	104	4	Jones	Jones	NNP
cord-006460-3ayc0hne	104	5	and	and	CC
cord-006460-3ayc0hne	104	6	Lowes	Lowes	NNP
cord-006460-3ayc0hne	104	7	[	[	-LRB-
cord-006460-3ayc0hne	104	8	18	18	CD
cord-006460-3ayc0hne	104	9	]	]	-RRB-
cord-006460-3ayc0hne	104	10	found	find	VBD
cord-006460-3ayc0hne	104	11	that	that	IN
cord-006460-3ayc0hne	104	12	SIRS	SIRS	NNP
cord-006460-3ayc0hne	104	13	is	be	VBZ
cord-006460-3ayc0hne	104	14	not	not	RB
cord-006460-3ayc0hne	104	15	a	a	DT
cord-006460-3ayc0hne	104	16	very	very	RB
cord-006460-3ayc0hne	104	17	good	good	JJ
cord-006460-3ayc0hne	104	18	predictor	predictor	NN
cord-006460-3ayc0hne	104	19	of	of	IN
cord-006460-3ayc0hne	104	20	bacteremia	bacteremia	NN
cord-006460-3ayc0hne	104	21	,	,	,
cord-006460-3ayc0hne	104	22	the	the	DT
cord-006460-3ayc0hne	104	23	positive	positive	JJ
cord-006460-3ayc0hne	104	24	predictive	predictive	JJ
cord-006460-3ayc0hne	104	25	value	value	NN
cord-006460-3ayc0hne	104	26	being	be	VBG
cord-006460-3ayc0hne	104	27	only	only	RB
cord-006460-3ayc0hne	104	28	7	7	CD
cord-006460-3ayc0hne	104	29	%	%	NN
cord-006460-3ayc0hne	104	30	.	.	.
cord-006460-3ayc0hne	105	1	SIRS	sirs	UH
cord-006460-3ayc0hne	105	2	,	,	,
cord-006460-3ayc0hne	105	3	MODS	MODS	NNP
cord-006460-3ayc0hne	105	4	and	and	CC
cord-006460-3ayc0hne	105	5	MOF	MOF	NNP
cord-006460-3ayc0hne	105	6	are	be	VBP
cord-006460-3ayc0hne	105	7	constructs	construct	NNS
cord-006460-3ayc0hne	105	8	or	or	CC
cord-006460-3ayc0hne	105	9	concepts	concept	NNS
cord-006460-3ayc0hne	105	10	.	.	.
cord-006460-3ayc0hne	106	1	They	-PRON-	PRP
cord-006460-3ayc0hne	106	2	are	be	VBP
cord-006460-3ayc0hne	106	3	not	not	RB
cord-006460-3ayc0hne	106	4	diseases	disease	NNS
cord-006460-3ayc0hne	106	5	or	or	CC
cord-006460-3ayc0hne	106	6	even	even	RB
cord-006460-3ayc0hne	106	7	syndromes	syndrome	NNS
cord-006460-3ayc0hne	106	8	.	.	.
cord-006460-3ayc0hne	107	1	They	-PRON-	PRP
cord-006460-3ayc0hne	107	2	can	can	MD
cord-006460-3ayc0hne	107	3	not	not	RB
cord-006460-3ayc0hne	107	4	be	be	VB
cord-006460-3ayc0hne	107	5	treated	treat	VBN
cord-006460-3ayc0hne	107	6	other	other	JJ
cord-006460-3ayc0hne	107	7	than	than	IN
cord-006460-3ayc0hne	107	8	to	to	TO
cord-006460-3ayc0hne	107	9	support	support	VB
cord-006460-3ayc0hne	107	10	organ	organ	NN
cord-006460-3ayc0hne	107	11	function	function	NN
cord-006460-3ayc0hne	107	12	.	.	.
cord-006460-3ayc0hne	108	1	MOF	MOF	NNP
cord-006460-3ayc0hne	108	2	is	be	VBZ
cord-006460-3ayc0hne	108	3	the	the	DT
cord-006460-3ayc0hne	108	4	final	final	JJ
cord-006460-3ayc0hne	108	5	common	common	JJ
cord-006460-3ayc0hne	108	6	pathway	pathway	NN
cord-006460-3ayc0hne	108	7	to	to	IN
cord-006460-3ayc0hne	108	8	death	death	NN
cord-006460-3ayc0hne	108	9	in	in	IN
cord-006460-3ayc0hne	108	10	the	the	DT
cord-006460-3ayc0hne	108	11	modern	modern	JJ
cord-006460-3ayc0hne	108	12	organsupporting	organsupporting	NN
cord-006460-3ayc0hne	108	13	intensive	intensive	JJ
cord-006460-3ayc0hne	108	14	care	care	NN
cord-006460-3ayc0hne	108	15	unit	unit	NN
cord-006460-3ayc0hne	108	16	(	(	-LRB-
cord-006460-3ayc0hne	108	17	ICU	ICU	NNP
cord-006460-3ayc0hne	108	18	)	)	-RRB-
cord-006460-3ayc0hne	108	19	.	.	.
cord-006460-3ayc0hne	109	1	Blakiston	Blakiston	NNP
cord-006460-3ayc0hne	109	2	's	's	POS
cord-006460-3ayc0hne	109	3	Gould	Gould	NNP
cord-006460-3ayc0hne	109	4	Medical	Medical	NNP
cord-006460-3ayc0hne	109	5	Dictionary	Dictionary	NNP
cord-006460-3ayc0hne	109	6	(	(	-LRB-
cord-006460-3ayc0hne	109	7	3rd	3rd	NNP
cord-006460-3ayc0hne	109	8	edition	edition	NN
cord-006460-3ayc0hne	109	9	)	)	-RRB-
cord-006460-3ayc0hne	109	10	defines	define	VBZ
cord-006460-3ayc0hne	109	11	a	a	DT
cord-006460-3ayc0hne	109	12	syndrome	syndrome	NN
cord-006460-3ayc0hne	109	13	as	as	IN
cord-006460-3ayc0hne	109	14	a	a	DT
cord-006460-3ayc0hne	109	15	group	group	NN
cord-006460-3ayc0hne	109	16	of	of	IN
cord-006460-3ayc0hne	109	17	symptoms	symptom	NNS
cord-006460-3ayc0hne	109	18	and	and	CC
cord-006460-3ayc0hne	109	19	signs	sign	NNS
cord-006460-3ayc0hne	109	20	which	which	WDT
cord-006460-3ayc0hne	109	21	,	,	,
cord-006460-3ayc0hne	109	22	when	when	WRB
cord-006460-3ayc0hne	109	23	considered	consider	VBN
cord-006460-3ayc0hne	109	24	together	together	RB
cord-006460-3ayc0hne	109	25	,	,	,
cord-006460-3ayc0hne	109	26	characterize	characterize	VB
cord-006460-3ayc0hne	109	27	a	a	DT
cord-006460-3ayc0hne	109	28	disease	disease	NN
cord-006460-3ayc0hne	109	29	or	or	CC
cord-006460-3ayc0hne	109	30	lesion	lesion	NN
cord-006460-3ayc0hne	109	31	[	[	-LRB-
cord-006460-3ayc0hne	109	32	19	19	CD
cord-006460-3ayc0hne	109	33	]	]	-RRB-
cord-006460-3ayc0hne	109	34	.	.	.
cord-006460-3ayc0hne	110	1	Thus	thus	RB
cord-006460-3ayc0hne	110	2	,	,	,
cord-006460-3ayc0hne	110	3	none	none	NN
cord-006460-3ayc0hne	110	4	of	of	IN
cord-006460-3ayc0hne	110	5	these	these	DT
cord-006460-3ayc0hne	110	6	concepts	concept	NNS
cord-006460-3ayc0hne	110	7	are	be	VBP
cord-006460-3ayc0hne	110	8	diseases	disease	NNS
cord-006460-3ayc0hne	110	9	and	and	CC
cord-006460-3ayc0hne	110	10	,	,	,
cord-006460-3ayc0hne	110	11	therefore	therefore	RB
cord-006460-3ayc0hne	110	12	,	,	,
cord-006460-3ayc0hne	110	13	are	be	VBP
cord-006460-3ayc0hne	110	14	not	not	RB
cord-006460-3ayc0hne	110	15	treatable	treatable	JJ
cord-006460-3ayc0hne	110	16	as	as	IN
cord-006460-3ayc0hne	110	17	such	such	JJ
cord-006460-3ayc0hne	110	18	.	.	.
cord-006460-3ayc0hne	111	1	In	in	IN
cord-006460-3ayc0hne	111	2	a	a	DT
cord-006460-3ayc0hne	111	3	recent	recent	JJ
cord-006460-3ayc0hne	111	4	article	article	NN
cord-006460-3ayc0hne	111	5	,	,	,
cord-006460-3ayc0hne	111	6	I	-PRON-	PRP
cord-006460-3ayc0hne	111	7	described	describe	VBD
cord-006460-3ayc0hne	111	8	the	the	DT
cord-006460-3ayc0hne	111	9	concept	concept	NN
cord-006460-3ayc0hne	111	10	(	(	-LRB-
cord-006460-3ayc0hne	111	11	shown	show	VBN
cord-006460-3ayc0hne	111	12	in	in	IN
cord-006460-3ayc0hne	111	13	Figure	figure	NN
cord-006460-3ayc0hne	111	14	1	1	CD
cord-006460-3ayc0hne	111	15	)	)	-RRB-
cord-006460-3ayc0hne	111	16	that	that	IN
cord-006460-3ayc0hne	111	17	SIRS	SIRS	NNP
cord-006460-3ayc0hne	111	18	to	to	IN
cord-006460-3ayc0hne	111	19	MODS	mod	NNS
cord-006460-3ayc0hne	111	20	to	to	IN
cord-006460-3ayc0hne	111	21	MOF	MOF	NNP
cord-006460-3ayc0hne	111	22	is	be	VBZ
cord-006460-3ayc0hne	111	23	simply	simply	RB
cord-006460-3ayc0hne	111	24	going	go	VBG
cord-006460-3ayc0hne	111	25	from	from	IN
cord-006460-3ayc0hne	111	26	sick	sick	JJ
cord-006460-3ayc0hne	111	27	to	to	IN
cord-006460-3ayc0hne	111	28	sicker	sick	JJR
cord-006460-3ayc0hne	111	29	to	to	IN
cord-006460-3ayc0hne	111	30	very	very	RB
cord-006460-3ayc0hne	111	31	sick	sick	JJ
cord-006460-3ayc0hne	111	32	[	[	-LRB-
cord-006460-3ayc0hne	111	33	20	20	CD
cord-006460-3ayc0hne	111	34	]	]	-RRB-
cord-006460-3ayc0hne	111	35	.	.	.
cord-006460-3ayc0hne	112	1	Some	some	DT
cord-006460-3ayc0hne	112	2	have	have	VBP
cord-006460-3ayc0hne	112	3	focused	focus	VBN
cord-006460-3ayc0hne	112	4	on	on	IN
cord-006460-3ayc0hne	112	5	SIRS	SIRS	NNP
cord-006460-3ayc0hne	112	6	indicating	indicate	VBG
cord-006460-3ayc0hne	112	7	an	an	DT
cord-006460-3ayc0hne	112	8	inflammatory	inflammatory	JJ
cord-006460-3ayc0hne	112	9	process	process	NN
cord-006460-3ayc0hne	112	10	.	.	.
cord-006460-3ayc0hne	113	1	As	as	IN
cord-006460-3ayc0hne	113	2	Goris	Goris	NNP
cord-006460-3ayc0hne	113	3	et	et	FW
cord-006460-3ayc0hne	113	4	al	al	NNP
cord-006460-3ayc0hne	113	5	.	.	.
cord-006460-3ayc0hne	114	1	[	[	-LRB-
cord-006460-3ayc0hne	114	2	21	21	CD
cord-006460-3ayc0hne	114	3	]	]	-RRB-
cord-006460-3ayc0hne	114	4	demonstrated	demonstrate	VBD
cord-006460-3ayc0hne	114	5	that	that	IN
cord-006460-3ayc0hne	114	6	inflammation	inflammation	NN
cord-006460-3ayc0hne	114	7	alone	alone	RB
cord-006460-3ayc0hne	114	8	,	,	,
cord-006460-3ayc0hne	114	9	as	as	IN
cord-006460-3ayc0hne	114	10	produced	produce	VBN
cord-006460-3ayc0hne	114	11	by	by	IN
cord-006460-3ayc0hne	114	12	Zymosan	Zymosan	NNP
cord-006460-3ayc0hne	114	13	in	in	IN
cord-006460-3ayc0hne	114	14	the	the	DT
cord-006460-3ayc0hne	114	15	peritoneal	peritoneal	JJ
cord-006460-3ayc0hne	114	16	cavity	cavity	NN
cord-006460-3ayc0hne	114	17	of	of	IN
cord-006460-3ayc0hne	114	18	animals	animal	NNS
cord-006460-3ayc0hne	114	19	,	,	,
cord-006460-3ayc0hne	114	20	can	can	MD
cord-006460-3ayc0hne	114	21	lead	lead	VB
cord-006460-3ayc0hne	114	22	to	to	IN
cord-006460-3ayc0hne	114	23	MOF	MOF	NNP
cord-006460-3ayc0hne	114	24	.	.	.
cord-006460-3ayc0hne	115	1	Nor	nor	CC
cord-006460-3ayc0hne	115	2	is	be	VBZ
cord-006460-3ayc0hne	115	3	inflammation	inflammation	NN
cord-006460-3ayc0hne	115	4	a	a	DT
cord-006460-3ayc0hne	115	5	disease	disease	NN
cord-006460-3ayc0hne	115	6	.	.	.
cord-006460-3ayc0hne	116	1	It	-PRON-	PRP
cord-006460-3ayc0hne	116	2	is	be	VBZ
cord-006460-3ayc0hne	116	3	a	a	DT
cord-006460-3ayc0hne	116	4	complex	complex	JJ
cord-006460-3ayc0hne	116	5	biologic	biologic	JJ
cord-006460-3ayc0hne	116	6	process	process	NN
cord-006460-3ayc0hne	116	7	of	of	IN
cord-006460-3ayc0hne	116	8	host	host	NN
cord-006460-3ayc0hne	116	9	defense	defense	NN
cord-006460-3ayc0hne	116	10	and	and	CC
cord-006460-3ayc0hne	116	11	repair	repair	NN
cord-006460-3ayc0hne	116	12	of	of	IN
cord-006460-3ayc0hne	116	13	injury	injury	NN
cord-006460-3ayc0hne	116	14	.	.	.
cord-006460-3ayc0hne	117	1	Many	many	JJ
cord-006460-3ayc0hne	117	2	years	year	NNS
cord-006460-3ayc0hne	117	3	ago	ago	RB
cord-006460-3ayc0hne	117	4	,	,	,
cord-006460-3ayc0hne	117	5	John	John	NNP
cord-006460-3ayc0hne	117	6	Hunter	Hunter	NNP
cord-006460-3ayc0hne	117	7	stated	state	VBD
cord-006460-3ayc0hne	117	8	that	that	IN
cord-006460-3ayc0hne	117	9	,	,	,
cord-006460-3ayc0hne	117	10	"	"	``
cord-006460-3ayc0hne	117	11	Inflammation	inflammation	NN
cord-006460-3ayc0hne	117	12	in	in	IN
cord-006460-3ayc0hne	117	13	itself	-PRON-	PRP
cord-006460-3ayc0hne	117	14	is	be	VBZ
cord-006460-3ayc0hne	117	15	not	not	RB
cord-006460-3ayc0hne	117	16	to	to	TO
cord-006460-3ayc0hne	117	17	be	be	VB
cord-006460-3ayc0hne	117	18	considered	consider	VBN
cord-006460-3ayc0hne	117	19	as	as	IN
cord-006460-3ayc0hne	117	20	a	a	DT
cord-006460-3ayc0hne	117	21	disease	disease	NN
cord-006460-3ayc0hne	117	22	-and	-and	:
cord-006460-3ayc0hne	117	23	in	in	IN
cord-006460-3ayc0hne	117	24	disease	disease	NN
cord-006460-3ayc0hne	117	25	,	,	,
cord-006460-3ayc0hne	117	26	where	where	WRB
cord-006460-3ayc0hne	117	27	it	-PRON-	PRP
cord-006460-3ayc0hne	117	28	can	can	MD
cord-006460-3ayc0hne	117	29	alter	alter	VB
cord-006460-3ayc0hne	117	30	the	the	DT
cord-006460-3ayc0hne	117	31	disease	disease	NN
cord-006460-3ayc0hne	117	32	mode	mode	NN
cord-006460-3ayc0hne	117	33	of	of	IN
cord-006460-3ayc0hne	117	34	action	action	NN
cord-006460-3ayc0hne	117	35	,	,	,
cord-006460-3ayc0hne	117	36	it	-PRON-	PRP
cord-006460-3ayc0hne	117	37	likewise	likewise	RB
cord-006460-3ayc0hne	117	38	leads	lead	VBZ
cord-006460-3ayc0hne	117	39	to	to	IN
cord-006460-3ayc0hne	117	40	a	a	DT
cord-006460-3ayc0hne	117	41	cure	cure	NN
cord-006460-3ayc0hne	117	42	;	;	:
cord-006460-3ayc0hne	117	43	but	but	CC
cord-006460-3ayc0hne	117	44	where	where	WRB
cord-006460-3ayc0hne	117	45	it	-PRON-	PRP
cord-006460-3ayc0hne	117	46	can	can	MD
cord-006460-3ayc0hne	117	47	not	not	RB
cord-006460-3ayc0hne	117	48	accomplish	accomplish	VB
cord-006460-3ayc0hne	117	49	that	that	DT
cord-006460-3ayc0hne	117	50	salutary	salutary	JJ
cord-006460-3ayc0hne	117	51	purpose	purpose	NN
cord-006460-3ayc0hne	117	52	,	,	,
cord-006460-3ayc0hne	117	53	it	-PRON-	PRP
cord-006460-3ayc0hne	117	54	does	do	VBZ
cord-006460-3ayc0hne	117	55	mischief	mischief	NN
cord-006460-3ayc0hne	117	56	"	"	''
cord-006460-3ayc0hne	117	57	[	[	-LRB-
cord-006460-3ayc0hne	117	58	22	22	CD
cord-006460-3ayc0hne	117	59	]	]	-RRB-
cord-006460-3ayc0hne	117	60	.	.	.
cord-006460-3ayc0hne	118	1	The	the	DT
cord-006460-3ayc0hne	118	2	scientific	scientific	JJ
cord-006460-3ayc0hne	118	3	advances	advance	NNS
cord-006460-3ayc0hne	118	4	of	of	IN
cord-006460-3ayc0hne	118	5	molecular	molecular	JJ
cord-006460-3ayc0hne	118	6	biology	biology	NN
cord-006460-3ayc0hne	118	7	developed	develop	VBD
cord-006460-3ayc0hne	118	8	a	a	DT
cord-006460-3ayc0hne	118	9	number	number	NN
cord-006460-3ayc0hne	118	10	of	of	IN
cord-006460-3ayc0hne	118	11	substances	substance	NNS
cord-006460-3ayc0hne	118	12	and	and	CC
cord-006460-3ayc0hne	118	13	approaches	approach	NNS
cord-006460-3ayc0hne	118	14	that	that	IN
cord-006460-3ayc0hne	118	15	,	,	,
cord-006460-3ayc0hne	118	16	in	in	IN
cord-006460-3ayc0hne	118	17	terms	term	NNS
cord-006460-3ayc0hne	118	18	of	of	IN
cord-006460-3ayc0hne	118	19	animal	animal	NN
cord-006460-3ayc0hne	118	20	experimentation	experimentation	NN
cord-006460-3ayc0hne	118	21	,	,	,
cord-006460-3ayc0hne	118	22	suggested	suggest	VBD
cord-006460-3ayc0hne	118	23	possible	possible	JJ
cord-006460-3ayc0hne	118	24	help	help	NN
cord-006460-3ayc0hne	118	25	for	for	IN
cord-006460-3ayc0hne	118	26	patients	patient	NNS
cord-006460-3ayc0hne	118	27	.	.	.
cord-006460-3ayc0hne	119	1	These	these	DT
cord-006460-3ayc0hne	119	2	were	be	VBD
cord-006460-3ayc0hne	119	3	called	call	VBN
cord-006460-3ayc0hne	119	4	"	"	``
cord-006460-3ayc0hne	119	5	magic	magic	JJ
cord-006460-3ayc0hne	119	6	bullets	bullet	NNS
cord-006460-3ayc0hne	119	7	"	"	''
cord-006460-3ayc0hne	119	8	after	after	IN
cord-006460-3ayc0hne	119	9	the	the	DT
cord-006460-3ayc0hne	119	10	concept	concept	NN
cord-006460-3ayc0hne	119	11	developed	develop	VBN
cord-006460-3ayc0hne	119	12	by	by	IN
cord-006460-3ayc0hne	119	13	Ehrlich	Ehrlich	NNP
cord-006460-3ayc0hne	119	14	and	and	CC
cord-006460-3ayc0hne	119	15	Morgenroth	Morgenroth	NNP
cord-006460-3ayc0hne	119	16	[	[	-LRB-
cord-006460-3ayc0hne	119	17	23	23	CD
cord-006460-3ayc0hne	119	18	]	]	-RRB-
cord-006460-3ayc0hne	119	19	at	at	IN
cord-006460-3ayc0hne	119	20	the	the	DT
cord-006460-3ayc0hne	119	21	turn	turn	NN
cord-006460-3ayc0hne	119	22	of	of	IN
cord-006460-3ayc0hne	119	23	the	the	DT
cord-006460-3ayc0hne	119	24	twentieth	twentieth	JJ
cord-006460-3ayc0hne	119	25	century	century	NN
cord-006460-3ayc0hne	119	26	.	.	.
cord-006460-3ayc0hne	120	1	There	there	EX
cord-006460-3ayc0hne	120	2	are	be	VBP
cord-006460-3ayc0hne	120	3	a	a	DT
cord-006460-3ayc0hne	120	4	number	number	NN
cord-006460-3ayc0hne	120	5	of	of	IN
cord-006460-3ayc0hne	120	6	socalled	socalled	JJ
cord-006460-3ayc0hne	120	7	magic	magic	JJ
cord-006460-3ayc0hne	120	8	bullets	bullet	NNS
cord-006460-3ayc0hne	120	9	that	that	WDT
cord-006460-3ayc0hne	120	10	have	have	VBP
cord-006460-3ayc0hne	120	11	failed	fail	VBN
cord-006460-3ayc0hne	120	12	to	to	TO
cord-006460-3ayc0hne	120	13	improve	improve	VB
cord-006460-3ayc0hne	120	14	overall	overall	JJ
cord-006460-3ayc0hne	120	15	mortality	mortality	NN
cord-006460-3ayc0hne	120	16	(	(	-LRB-
cord-006460-3ayc0hne	120	17	Table	table	NN
cord-006460-3ayc0hne	120	18	1	1	CD
cord-006460-3ayc0hne	120	19	)	)	-RRB-
cord-006460-3ayc0hne	120	20	.	.	.
cord-006460-3ayc0hne	121	1	For	for	IN
cord-006460-3ayc0hne	121	2	details	detail	NNS
cord-006460-3ayc0hne	121	3	and	and	CC
cord-006460-3ayc0hne	121	4	references	reference	NNS
cord-006460-3ayc0hne	121	5	to	to	IN
cord-006460-3ayc0hne	121	6	these	these	DT
cord-006460-3ayc0hne	121	7	trials	trial	NNS
cord-006460-3ayc0hne	121	8	and	and	CC
cord-006460-3ayc0hne	121	9	reviews	review	NNS
cord-006460-3ayc0hne	121	10	of	of	IN
cord-006460-3ayc0hne	121	11	them	-PRON-	PRP
cord-006460-3ayc0hne	121	12	,	,	,
cord-006460-3ayc0hne	121	13	I	-PRON-	PRP
cord-006460-3ayc0hne	121	14	refer	refer	VBP
cord-006460-3ayc0hne	121	15	the	the	DT
cord-006460-3ayc0hne	121	16	reader	reader	NN
cord-006460-3ayc0hne	121	17	to	to	IN
cord-006460-3ayc0hne	121	18	papers	paper	NNS
cord-006460-3ayc0hne	121	19	by	by	IN
cord-006460-3ayc0hne	121	20	Opal	Opal	NNP
cord-006460-3ayc0hne	121	21	[	[	-LRB-
cord-006460-3ayc0hne	121	22	24	24	CD
cord-006460-3ayc0hne	121	23	]	]	-RRB-
cord-006460-3ayc0hne	121	24	,	,	,
cord-006460-3ayc0hne	121	25	Eidelman	Eidelman	NNP
cord-006460-3ayc0hne	121	26	and	and	CC
cord-006460-3ayc0hne	121	27	Sprung	Sprung	NNP
cord-006460-3ayc0hne	121	28	[	[	-LRB-
cord-006460-3ayc0hne	121	29	25	25	CD
cord-006460-3ayc0hne	121	30	]	]	-RRB-
cord-006460-3ayc0hne	121	31	,	,	,
cord-006460-3ayc0hne	121	32	the	the	DT
cord-006460-3ayc0hne	121	33	late	late	JJ
cord-006460-3ayc0hne	121	34	Roger	Roger	NNP
cord-006460-3ayc0hne	121	35	Bone	Bone	NNP
cord-006460-3ayc0hne	121	36	[	[	-LRB-
cord-006460-3ayc0hne	121	37	26	26	CD
cord-006460-3ayc0hne	121	38	]	]	-RRB-
cord-006460-3ayc0hne	121	39	,	,	,
cord-006460-3ayc0hne	121	40	and	and	CC
cord-006460-3ayc0hne	121	41	Zeni	Zeni	NNP
cord-006460-3ayc0hne	121	42	et	et	FW
cord-006460-3ayc0hne	121	43	al	al	NNP
cord-006460-3ayc0hne	121	44	.	.	.
cord-006460-3ayc0hne	122	1	[	[	-LRB-
cord-006460-3ayc0hne	122	2	27	27	CD
cord-006460-3ayc0hne	122	3	]	]	-RRB-
cord-006460-3ayc0hne	122	4	.	.	.
cord-006460-3ayc0hne	123	1	I	-PRON-	PRP
cord-006460-3ayc0hne	123	2	have	have	VBP
cord-006460-3ayc0hne	123	3	also	also	RB
cord-006460-3ayc0hne	123	4	reviewed	review	VBN
cord-006460-3ayc0hne	123	5	the	the	DT
cord-006460-3ayc0hne	123	6	reasons	reason	NNS
cord-006460-3ayc0hne	123	7	why	why	WRB
cord-006460-3ayc0hne	123	8	I	-PRON-	PRP
cord-006460-3ayc0hne	123	9	think	think	VBP
cord-006460-3ayc0hne	123	10	many	many	JJ
cord-006460-3ayc0hne	123	11	of	of	IN
cord-006460-3ayc0hne	123	12	these	these	DT
cord-006460-3ayc0hne	123	13	trials	trial	NNS
cord-006460-3ayc0hne	123	14	have	have	VBP
cord-006460-3ayc0hne	123	15	failed	fail	VBN
cord-006460-3ayc0hne	123	16	[	[	-LRB-
cord-006460-3ayc0hne	123	17	28	28	CD
cord-006460-3ayc0hne	123	18	]	]	-RRB-
cord-006460-3ayc0hne	123	19	.	.	.
cord-006460-3ayc0hne	124	1	There	there	EX
cord-006460-3ayc0hne	124	2	have	have	VBP
cord-006460-3ayc0hne	124	3	been	be	VBN
cord-006460-3ayc0hne	124	4	more	more	RBR
cord-006460-3ayc0hne	124	5	recent	recent	JJ
cord-006460-3ayc0hne	124	6	clinical	clinical	JJ
cord-006460-3ayc0hne	124	7	trials	trial	NNS
cord-006460-3ayc0hne	124	8	using	use	VBG
cord-006460-3ayc0hne	124	9	what	what	WP
cord-006460-3ayc0hne	124	10	some	some	DT
cord-006460-3ayc0hne	124	11	thought	thought	NN
cord-006460-3ayc0hne	124	12	might	may	MD
cord-006460-3ayc0hne	124	13	be	be	VB
cord-006460-3ayc0hne	124	14	magic	magic	JJ
cord-006460-3ayc0hne	124	15	bullets	bullet	NNS
cord-006460-3ayc0hne	124	16	and	and	CC
cord-006460-3ayc0hne	124	17	these	these	DT
cord-006460-3ayc0hne	124	18	have	have	VBP
cord-006460-3ayc0hne	124	19	also	also	RB
cord-006460-3ayc0hne	124	20	failed	fail	VBN
cord-006460-3ayc0hne	124	21	.	.	.
cord-006460-3ayc0hne	125	1	One	one	CD
cord-006460-3ayc0hne	125	2	such	such	JJ
cord-006460-3ayc0hne	125	3	trial	trial	NN
cord-006460-3ayc0hne	125	4	used	use	VBN
cord-006460-3ayc0hne	125	5	Diaspirin	Diaspirin	NNP
cord-006460-3ayc0hne	125	6	cross	cross	VB
cord-006460-3ayc0hne	125	7	-	-	VBN
cord-006460-3ayc0hne	125	8	linked	link	VBN
cord-006460-3ayc0hne	125	9	Hgb	Hgb	NNP
cord-006460-3ayc0hne	125	10	,	,	,
cord-006460-3ayc0hne	125	11	which	which	WDT
cord-006460-3ayc0hne	125	12	was	be	VBD
cord-006460-3ayc0hne	125	13	found	find	VBN
cord-006460-3ayc0hne	125	14	to	to	TO
cord-006460-3ayc0hne	125	15	increase	increase	VB
cord-006460-3ayc0hne	125	16	mortality	mortality	NN
cord-006460-3ayc0hne	125	17	[	[	-LRB-
cord-006460-3ayc0hne	125	18	29	29	CD
cord-006460-3ayc0hne	125	19	]	]	-RRB-
cord-006460-3ayc0hne	125	20	.	.	.
cord-006460-3ayc0hne	126	1	Trials	trial	NNS
cord-006460-3ayc0hne	126	2	were	be	VBD
cord-006460-3ayc0hne	126	3	halted	halt	VBN
cord-006460-3ayc0hne	126	4	.	.	.
cord-006460-3ayc0hne	127	1	N	n	NN
cord-006460-3ayc0hne	127	2	-	-	HYPH
cord-006460-3ayc0hne	127	3	acetylcysteine	acetylcysteine	NN
cord-006460-3ayc0hne	127	4	,	,	,
cord-006460-3ayc0hne	127	5	an	an	DT
cord-006460-3ayc0hne	127	6	antioxidant	antioxidant	NN
cord-006460-3ayc0hne	127	7	,	,	,
cord-006460-3ayc0hne	127	8	was	be	VBD
cord-006460-3ayc0hne	127	9	found	find	VBN
cord-006460-3ayc0hne	127	10	to	to	TO
cord-006460-3ayc0hne	127	11	be	be	VB
cord-006460-3ayc0hne	127	12	of	of	IN
cord-006460-3ayc0hne	127	13	no	no	DT
cord-006460-3ayc0hne	127	14	help	help	NN
cord-006460-3ayc0hne	127	15	in	in	IN
cord-006460-3ayc0hne	127	16	patients	patient	NNS
cord-006460-3ayc0hne	127	17	and	and	CC
cord-006460-3ayc0hne	127	18	actually	actually	RB
cord-006460-3ayc0hne	127	19	may	may	MD
cord-006460-3ayc0hne	127	20	be	be	VB
cord-006460-3ayc0hne	127	21	harmful	harmful	JJ
cord-006460-3ayc0hne	127	22	despite	despite	IN
cord-006460-3ayc0hne	127	23	early	early	JJ
cord-006460-3ayc0hne	127	24	encouraging	encouraging	JJ
cord-006460-3ayc0hne	127	25	results	result	NNS
cord-006460-3ayc0hne	127	26	in	in	IN
cord-006460-3ayc0hne	127	27	adult	adult	JJ
cord-006460-3ayc0hne	127	28	respiratory	respiratory	JJ
cord-006460-3ayc0hne	127	29	distress	distress	NN
cord-006460-3ayc0hne	127	30	syndrome	syndrome	NN
cord-006460-3ayc0hne	127	31	(	(	-LRB-
cord-006460-3ayc0hne	127	32	ARDS	ARDS	NNP
cord-006460-3ayc0hne	127	33	)	)	-RRB-
cord-006460-3ayc0hne	127	34	[	[	-LRB-
cord-006460-3ayc0hne	127	35	30	30	CD
cord-006460-3ayc0hne	127	36	]	]	-RRB-
cord-006460-3ayc0hne	127	37	.	.	.
cord-006460-3ayc0hne	128	1	The	the	DT
cord-006460-3ayc0hne	128	2	use	use	NN
cord-006460-3ayc0hne	128	3	of	of	IN
cord-006460-3ayc0hne	128	4	Leptin	Leptin	NNP
cord-006460-3ayc0hne	128	5	to	to	TO
cord-006460-3ayc0hne	128	6	control	control	VB
cord-006460-3ayc0hne	128	7	obesity	obesity	NN
cord-006460-3ayc0hne	128	8	has	have	VBZ
cord-006460-3ayc0hne	128	9	not	not	RB
cord-006460-3ayc0hne	128	10	been	be	VBN
cord-006460-3ayc0hne	128	11	impressive	impressive	JJ
cord-006460-3ayc0hne	128	12	in	in	IN
cord-006460-3ayc0hne	128	13	clinical	clinical	JJ
cord-006460-3ayc0hne	128	14	trials	trial	NNS
cord-006460-3ayc0hne	128	15	[	[	-LRB-
cord-006460-3ayc0hne	128	16	31	31	CD
cord-006460-3ayc0hne	128	17	]	]	-RRB-
cord-006460-3ayc0hne	128	18	and	and	CC
cord-006460-3ayc0hne	128	19	the	the	DT
cord-006460-3ayc0hne	128	20	NOS	NOS	NNP
cord-006460-3ayc0hne	128	21	inhibitor	inhibitor	NN
cord-006460-3ayc0hne	128	22	546C88	546c88	CD
cord-006460-3ayc0hne	128	23	increased	increase	VBN
cord-006460-3ayc0hne	128	24	mortality	mortality	NN
cord-006460-3ayc0hne	128	25	[	[	-LRB-
cord-006460-3ayc0hne	128	26	4	4	CD
cord-006460-3ayc0hne	128	27	]	]	-RRB-
cord-006460-3ayc0hne	128	28	.	.	.
cord-006460-3ayc0hne	129	1	Ibuprofen	Ibuprofen	NNP
cord-006460-3ayc0hne	129	2	did	do	VBD
cord-006460-3ayc0hne	129	3	not	not	RB
cord-006460-3ayc0hne	129	4	decrease	decrease	VB
cord-006460-3ayc0hne	129	5	shock	shock	NN
cord-006460-3ayc0hne	129	6	,	,	,
cord-006460-3ayc0hne	129	7	ARDS	ARDS	NNP
cord-006460-3ayc0hne	129	8	or	or	CC
cord-006460-3ayc0hne	129	9	mortality	mortality	NN
cord-006460-3ayc0hne	129	10	in	in	IN
cord-006460-3ayc0hne	129	11	septic	septic	JJ
cord-006460-3ayc0hne	129	12	patients	patient	NNS
cord-006460-3ayc0hne	129	13	[	[	-LRB-
cord-006460-3ayc0hne	129	14	32	32	CD
cord-006460-3ayc0hne	129	15	]	]	-RRB-
cord-006460-3ayc0hne	129	16	.	.	.
cord-006460-3ayc0hne	130	1	Antithrombin	Antithrombin	NNP
cord-006460-3ayc0hne	130	2	III	iii	CD
cord-006460-3ayc0hne	130	3	treatment	treatment	NN
cord-006460-3ayc0hne	130	4	in	in	IN
cord-006460-3ayc0hne	130	5	severely	severely	RB
cord-006460-3ayc0hne	130	6	injured	injure	VBN
cord-006460-3ayc0hne	130	7	patients	patient	NNS
cord-006460-3ayc0hne	130	8	did	do	VBD
cord-006460-3ayc0hne	130	9	not	not	RB
cord-006460-3ayc0hne	130	10	attenuate	attenuate	VB
cord-006460-3ayc0hne	130	11	the	the	DT
cord-006460-3ayc0hne	130	12	inflammatory	inflammatory	JJ
cord-006460-3ayc0hne	130	13	response	response	NN
cord-006460-3ayc0hne	130	14	or	or	CC
cord-006460-3ayc0hne	130	15	improve	improve	VB
cord-006460-3ayc0hne	130	16	outcome	outcome	NN
cord-006460-3ayc0hne	130	17	[	[	-LRB-
cord-006460-3ayc0hne	130	18	33	33	CD
cord-006460-3ayc0hne	130	19	]	]	-RRB-
cord-006460-3ayc0hne	130	20	.	.	.
cord-006460-3ayc0hne	131	1	Another	another	DT
cord-006460-3ayc0hne	131	2	study	study	NN
cord-006460-3ayc0hne	131	3	of	of	IN
cord-006460-3ayc0hne	131	4	a	a	DT
cord-006460-3ayc0hne	131	5	platelet	platelet	NN
cord-006460-3ayc0hne	131	6	-	-	HYPH
cord-006460-3ayc0hne	131	7	activating	activate	VBG
cord-006460-3ayc0hne	131	8	factor	factor	NN
cord-006460-3ayc0hne	131	9	(	(	-LRB-
cord-006460-3ayc0hne	131	10	PAF	PAF	NNP
cord-006460-3ayc0hne	131	11	)	)	-RRB-
cord-006460-3ayc0hne	131	12	receptor	receptor	NN
cord-006460-3ayc0hne	131	13	(	(	-LRB-
cord-006460-3ayc0hne	131	14	BB-882	bb-882	NN
cord-006460-3ayc0hne	131	15	)	)	-RRB-
cord-006460-3ayc0hne	131	16	antagonist	antagonist	NN
cord-006460-3ayc0hne	131	17	in	in	IN
cord-006460-3ayc0hne	131	18	septic	septic	JJ
cord-006460-3ayc0hne	131	19	patients	patient	NNS
cord-006460-3ayc0hne	131	20	also	also	RB
cord-006460-3ayc0hne	131	21	offered	offer	VBD
cord-006460-3ayc0hne	131	22	no	no	DT
cord-006460-3ayc0hne	131	23	advantages	advantage	NNS
cord-006460-3ayc0hne	131	24	[	[	-LRB-
cord-006460-3ayc0hne	131	25	34	34	CD
cord-006460-3ayc0hne	131	26	]	]	-RRB-
cord-006460-3ayc0hne	131	27	.	.	.
cord-006460-3ayc0hne	132	1	Why	why	WRB
cord-006460-3ayc0hne	132	2	have	have	VBP
cord-006460-3ayc0hne	132	3	there	there	EX
cord-006460-3ayc0hne	132	4	been	be	VBN
cord-006460-3ayc0hne	132	5	failures	failure	NNS
cord-006460-3ayc0hne	132	6	of	of	IN
cord-006460-3ayc0hne	132	7	so	so	RB
cord-006460-3ayc0hne	132	8	many	many	JJ
cord-006460-3ayc0hne	132	9	potential	potential	JJ
cord-006460-3ayc0hne	132	10	magic	magic	JJ
cord-006460-3ayc0hne	132	11	bullets	bullet	NNS
cord-006460-3ayc0hne	132	12	?	?	.
cord-006460-3ayc0hne	133	1	Many	many	JJ
cord-006460-3ayc0hne	133	2	reasons	reason	NNS
cord-006460-3ayc0hne	133	3	have	have	VBP
cord-006460-3ayc0hne	133	4	been	be	VBN
cord-006460-3ayc0hne	133	5	proposed	propose	VBN
cord-006460-3ayc0hne	133	6	by	by	IN
cord-006460-3ayc0hne	133	7	a	a	DT
cord-006460-3ayc0hne	133	8	number	number	NN
cord-006460-3ayc0hne	133	9	of	of	IN
cord-006460-3ayc0hne	133	10	authors	author	NNS
cord-006460-3ayc0hne	133	11	[	[	-LRB-
cord-006460-3ayc0hne	133	12	24	24	CD
cord-006460-3ayc0hne	133	13	,	,	,
cord-006460-3ayc0hne	133	14	25	25	CD
cord-006460-3ayc0hne	133	15	,	,	,
cord-006460-3ayc0hne	133	16	26	26	CD
cord-006460-3ayc0hne	133	17	,	,	,
cord-006460-3ayc0hne	133	18	27	27	CD
cord-006460-3ayc0hne	133	19	,	,	,
cord-006460-3ayc0hne	133	20	28	28	CD
cord-006460-3ayc0hne	133	21	]	]	-RRB-
cord-006460-3ayc0hne	133	22	.	.	.
cord-006460-3ayc0hne	134	1	The	the	DT
cord-006460-3ayc0hne	134	2	three	three	CD
cord-006460-3ayc0hne	134	3	major	major	JJ
cord-006460-3ayc0hne	134	4	reasons	reason	NNS
cord-006460-3ayc0hne	134	5	that	that	WDT
cord-006460-3ayc0hne	134	6	I	-PRON-	PRP
cord-006460-3ayc0hne	134	7	described	describe	VBD
cord-006460-3ayc0hne	134	8	earlier	early	RBR
cord-006460-3ayc0hne	134	9	for	for	IN
cord-006460-3ayc0hne	134	10	the	the	DT
cord-006460-3ayc0hne	134	11	discrepancy	discrepancy	NN
cord-006460-3ayc0hne	134	12	between	between	IN
cord-006460-3ayc0hne	134	13	science	science	NN
cord-006460-3ayc0hne	134	14	and	and	CC
cord-006460-3ayc0hne	134	15	patient	patient	NN
cord-006460-3ayc0hne	134	16	care	care	NN
cord-006460-3ayc0hne	134	17	also	also	RB
cord-006460-3ayc0hne	134	18	apply	apply	VBP
cord-006460-3ayc0hne	134	19	here	here	RB
cord-006460-3ayc0hne	134	20	.	.	.
cord-006460-3ayc0hne	135	1	In	in	IN
cord-006460-3ayc0hne	135	2	addition	addition	NN
cord-006460-3ayc0hne	135	3	,	,	,
cord-006460-3ayc0hne	135	4	specific	specific	JJ
cord-006460-3ayc0hne	135	5	problems	problem	NNS
cord-006460-3ayc0hne	135	6	affect	affect	VBP
cord-006460-3ayc0hne	135	7	trials	trial	NNS
cord-006460-3ayc0hne	135	8	of	of	IN
cord-006460-3ayc0hne	135	9	"	"	``
cord-006460-3ayc0hne	135	10	magic	magic	JJ
cord-006460-3ayc0hne	135	11	bullets	bullet	NNS
cord-006460-3ayc0hne	135	12	"	"	''
cord-006460-3ayc0hne	135	13	,	,	,
cord-006460-3ayc0hne	135	14	including	include	VBG
cord-006460-3ayc0hne	135	15	:	:	:
cord-006460-3ayc0hne	135	16	1	1	CD
cord-006460-3ayc0hne	135	17	.	.	.
cord-006460-3ayc0hne	136	1	The	the	DT
cord-006460-3ayc0hne	136	2	causality	causality	NN
cord-006460-3ayc0hne	136	3	of	of	IN
cord-006460-3ayc0hne	136	4	disease	disease	NN
cord-006460-3ayc0hne	136	5	:	:	:
cord-006460-3ayc0hne	136	6	many	many	JJ
cord-006460-3ayc0hne	136	7	different	different	JJ
cord-006460-3ayc0hne	136	8	complex	complex	JJ
cord-006460-3ayc0hne	136	9	diseases	disease	NNS
cord-006460-3ayc0hne	136	10	are	be	VBP
cord-006460-3ayc0hne	136	11	being	be	VBG
cord-006460-3ayc0hne	136	12	lumped	lump	VBN
cord-006460-3ayc0hne	136	13	together	together	RB
cord-006460-3ayc0hne	136	14	and	and	CC
cord-006460-3ayc0hne	136	15	treated	treat	VBN
cord-006460-3ayc0hne	136	16	with	with	IN
cord-006460-3ayc0hne	136	17	one	one	CD
cord-006460-3ayc0hne	136	18	of	of	IN
cord-006460-3ayc0hne	136	19	these	these	DT
cord-006460-3ayc0hne	136	20	magic	magic	JJ
cord-006460-3ayc0hne	136	21	bullets	bullet	NNS
cord-006460-3ayc0hne	136	22	.	.	.
cord-006460-3ayc0hne	137	1	SIRS	SIRS	NNP
cord-006460-3ayc0hne	137	2	has	have	VBZ
cord-006460-3ayc0hne	137	3	been	be	VBN
cord-006460-3ayc0hne	137	4	used	use	VBN
cord-006460-3ayc0hne	137	5	as	as	IN
cord-006460-3ayc0hne	137	6	the	the	DT
cord-006460-3ayc0hne	137	7	entry	entry	NN
cord-006460-3ayc0hne	137	8	criteria	criterion	NNS
cord-006460-3ayc0hne	137	9	in	in	IN
cord-006460-3ayc0hne	137	10	some	some	DT
cord-006460-3ayc0hne	137	11	studies	study	NNS
cord-006460-3ayc0hne	137	12	.	.	.
cord-006460-3ayc0hne	138	1	It	-PRON-	PRP
cord-006460-3ayc0hne	138	2	is	be	VBZ
cord-006460-3ayc0hne	138	3	no	no	DT
cord-006460-3ayc0hne	138	4	wonder	wonder	NN
cord-006460-3ayc0hne	138	5	that	that	IN
cord-006460-3ayc0hne	138	6	they	-PRON-	PRP
cord-006460-3ayc0hne	138	7	have	have	VBP
cord-006460-3ayc0hne	138	8	failed	fail	VBN
cord-006460-3ayc0hne	138	9	to	to	TO
cord-006460-3ayc0hne	138	10	improve	improve	VB
cord-006460-3ayc0hne	138	11	28-day	28-day	CD
cord-006460-3ayc0hne	138	12	mortality	mortality	NN
cord-006460-3ayc0hne	138	13	,	,	,
cord-006460-3ayc0hne	138	14	which	which	WDT
cord-006460-3ayc0hne	138	15	is	be	VBZ
cord-006460-3ayc0hne	138	16	the	the	DT
cord-006460-3ayc0hne	138	17	usual	usual	JJ
cord-006460-3ayc0hne	138	18	endpoint	endpoint	NN
cord-006460-3ayc0hne	138	19	for	for	IN
cord-006460-3ayc0hne	138	20	success	success	NN
cord-006460-3ayc0hne	138	21	.	.	.
cord-006460-3ayc0hne	139	1	I	-PRON-	PRP
cord-006460-3ayc0hne	139	2	do	do	VBP
cord-006460-3ayc0hne	139	3	not	not	RB
cord-006460-3ayc0hne	139	4	believe	believe	VB
cord-006460-3ayc0hne	139	5	that	that	IN
cord-006460-3ayc0hne	139	6	there	there	EX
cord-006460-3ayc0hne	139	7	is	be	VBZ
cord-006460-3ayc0hne	139	8	a	a	DT
cord-006460-3ayc0hne	139	9	single	single	JJ
cord-006460-3ayc0hne	139	10	treatment	treatment	NN
cord-006460-3ayc0hne	139	11	or	or	CC
cord-006460-3ayc0hne	139	12	agent	agent	NN
cord-006460-3ayc0hne	139	13	which	which	WDT
cord-006460-3ayc0hne	139	14	will	will	MD
cord-006460-3ayc0hne	139	15	help	help	VB
cord-006460-3ayc0hne	139	16	all	all	DT
cord-006460-3ayc0hne	139	17	or	or	CC
cord-006460-3ayc0hne	139	18	many	many	JJ
cord-006460-3ayc0hne	139	19	different	different	JJ
cord-006460-3ayc0hne	139	20	complex	complex	JJ
cord-006460-3ayc0hne	139	21	disease	disease	NN
cord-006460-3ayc0hne	139	22	processes	process	NNS
cord-006460-3ayc0hne	139	23	in	in	IN
cord-006460-3ayc0hne	139	24	patients	patient	NNS
cord-006460-3ayc0hne	139	25	.	.	.
cord-006460-3ayc0hne	140	1	2	2	LS
cord-006460-3ayc0hne	140	2	.	.	.
cord-006460-3ayc0hne	141	1	Redundancy	redundancy	NN
cord-006460-3ayc0hne	141	2	and	and	CC
cord-006460-3ayc0hne	141	3	overlap	overlap	NN
cord-006460-3ayc0hne	141	4	of	of	IN
cord-006460-3ayc0hne	141	5	mediators	mediator	NNS
cord-006460-3ayc0hne	141	6	:	:	:
cord-006460-3ayc0hne	141	7	there	there	EX
cord-006460-3ayc0hne	141	8	is	be	VBZ
cord-006460-3ayc0hne	141	9	considerable	considerable	JJ
cord-006460-3ayc0hne	141	10	overlap	overlap	NN
cord-006460-3ayc0hne	141	11	of	of	IN
cord-006460-3ayc0hne	141	12	the	the	DT
cord-006460-3ayc0hne	141	13	activities	activity	NNS
cord-006460-3ayc0hne	141	14	of	of	IN
cord-006460-3ayc0hne	141	15	cytokines	cytokine	NNS
cord-006460-3ayc0hne	141	16	and	and	CC
cord-006460-3ayc0hne	141	17	other	other	JJ
cord-006460-3ayc0hne	141	18	mediators	mediator	NNS
cord-006460-3ayc0hne	141	19	.	.	.
cord-006460-3ayc0hne	142	1	3	3	LS
cord-006460-3ayc0hne	142	2	.	.	.
cord-006460-3ayc0hne	143	1	There	there	EX
cord-006460-3ayc0hne	143	2	is	be	VBZ
cord-006460-3ayc0hne	143	3	no	no	DT
cord-006460-3ayc0hne	143	4	single	single	JJ
cord-006460-3ayc0hne	143	5	factor	factor	NN
cord-006460-3ayc0hne	143	6	that	that	WDT
cord-006460-3ayc0hne	143	7	acts	act	VBZ
cord-006460-3ayc0hne	143	8	as	as	IN
cord-006460-3ayc0hne	143	9	the	the	DT
cord-006460-3ayc0hne	143	10	lethal	lethal	JJ
cord-006460-3ayc0hne	143	11	activator	activator	NN
cord-006460-3ayc0hne	143	12	.	.	.
cord-006460-3ayc0hne	144	1	4	4	LS
cord-006460-3ayc0hne	144	2	.	.	.
cord-006460-3ayc0hne	145	1	The	the	DT
cord-006460-3ayc0hne	145	2	timing	timing	NN
cord-006460-3ayc0hne	145	3	of	of	IN
cord-006460-3ayc0hne	145	4	treatment	treatment	NN
cord-006460-3ayc0hne	145	5	is	be	VBZ
cord-006460-3ayc0hne	145	6	extremely	extremely	RB
cord-006460-3ayc0hne	145	7	important	important	JJ
cord-006460-3ayc0hne	145	8	.	.	.
cord-006460-3ayc0hne	146	1	In	in	IN
cord-006460-3ayc0hne	146	2	experimental	experimental	JJ
cord-006460-3ayc0hne	146	3	studies	study	NNS
cord-006460-3ayc0hne	146	4	in	in	IN
cord-006460-3ayc0hne	146	5	animals	animal	NNS
cord-006460-3ayc0hne	146	6	,	,	,
cord-006460-3ayc0hne	146	7	pretreatment	pretreatment	NN
cord-006460-3ayc0hne	146	8	before	before	IN
cord-006460-3ayc0hne	146	9	the	the	DT
cord-006460-3ayc0hne	146	10	insult	insult	NN
cord-006460-3ayc0hne	146	11	will	will	MD
cord-006460-3ayc0hne	146	12	help	help	VB
cord-006460-3ayc0hne	146	13	.	.	.
cord-006460-3ayc0hne	147	1	Obviously	obviously	RB
cord-006460-3ayc0hne	147	2	,	,	,
cord-006460-3ayc0hne	147	3	this	this	DT
cord-006460-3ayc0hne	147	4	can	can	MD
cord-006460-3ayc0hne	147	5	not	not	RB
cord-006460-3ayc0hne	147	6	be	be	VB
cord-006460-3ayc0hne	147	7	performed	perform	VBN
cord-006460-3ayc0hne	147	8	for	for	IN
cord-006460-3ayc0hne	147	9	injured	injure	VBN
cord-006460-3ayc0hne	147	10	,	,	,
cord-006460-3ayc0hne	147	11	sick	sick	JJ
cord-006460-3ayc0hne	147	12	or	or	CC
cord-006460-3ayc0hne	147	13	septic	septic	JJ
cord-006460-3ayc0hne	147	14	patients	patient	NNS
cord-006460-3ayc0hne	147	15	.	.	.
cord-006460-3ayc0hne	148	1	5	5	LS
cord-006460-3ayc0hne	148	2	.	.	.
cord-006460-3ayc0hne	149	1	There	there	EX
cord-006460-3ayc0hne	149	2	is	be	VBZ
cord-006460-3ayc0hne	149	3	the	the	DT
cord-006460-3ayc0hne	149	4	problem	problem	NN
cord-006460-3ayc0hne	149	5	of	of	IN
cord-006460-3ayc0hne	149	6	modulation	modulation	NN
cord-006460-3ayc0hne	149	7	of	of	IN
cord-006460-3ayc0hne	149	8	an	an	DT
cord-006460-3ayc0hne	149	9	essential	essential	JJ
cord-006460-3ayc0hne	149	10	biologic	biologic	JJ
cord-006460-3ayc0hne	149	11	function	function	NN
cord-006460-3ayc0hne	149	12	-inflammation	-inflammation	NN
cord-006460-3ayc0hne	149	13	.	.	.
cord-006460-3ayc0hne	150	1	Can	Can	MD
cord-006460-3ayc0hne	150	2	we	-PRON-	PRP
cord-006460-3ayc0hne	150	3	control	control	VB
cord-006460-3ayc0hne	150	4	inflammation	inflammation	NN
cord-006460-3ayc0hne	150	5	without	without	IN
cord-006460-3ayc0hne	150	6	doing	do	VBG
cord-006460-3ayc0hne	150	7	harm	harm	NN
cord-006460-3ayc0hne	150	8	to	to	IN
cord-006460-3ayc0hne	150	9	the	the	DT
cord-006460-3ayc0hne	150	10	host	host	NN
cord-006460-3ayc0hne	150	11	?	?	.
cord-006460-3ayc0hne	151	1	That	that	DT
cord-006460-3ayc0hne	151	2	is	be	VBZ
cord-006460-3ayc0hne	151	3	a	a	DT
cord-006460-3ayc0hne	151	4	real	real	JJ
cord-006460-3ayc0hne	151	5	question	question	NN
cord-006460-3ayc0hne	151	6	that	that	WDT
cord-006460-3ayc0hne	151	7	has	have	VBZ
cord-006460-3ayc0hne	151	8	not	not	RB
cord-006460-3ayc0hne	151	9	been	be	VBN
cord-006460-3ayc0hne	151	10	resolved	resolve	VBN
cord-006460-3ayc0hne	151	11	.	.	.
cord-006460-3ayc0hne	152	1	6	6	LS
cord-006460-3ayc0hne	152	2	.	.	.
cord-006460-3ayc0hne	153	1	Is	be	VBZ
cord-006460-3ayc0hne	153	2	there	there	EX
cord-006460-3ayc0hne	153	3	immune	immune	JJ
cord-006460-3ayc0hne	153	4	deficiency	deficiency	NN
cord-006460-3ayc0hne	153	5	or	or	CC
cord-006460-3ayc0hne	153	6	immune	immune	JJ
cord-006460-3ayc0hne	153	7	excess	excess	NN
cord-006460-3ayc0hne	153	8	?	?	.
cord-006460-3ayc0hne	154	1	Perhaps	perhaps	RB
cord-006460-3ayc0hne	154	2	both	both	DT
cord-006460-3ayc0hne	154	3	occur	occur	VBP
cord-006460-3ayc0hne	154	4	.	.	.
cord-006460-3ayc0hne	155	1	T	t	NN
cord-006460-3ayc0hne	155	2	-	-	HYPH
cord-006460-3ayc0hne	155	3	cell	cell	NN
cord-006460-3ayc0hne	155	4	immune	immune	JJ
cord-006460-3ayc0hne	155	5	deficiency	deficiency	NN
cord-006460-3ayc0hne	155	6	occurs	occur	VBZ
cord-006460-3ayc0hne	155	7	after	after	IN
cord-006460-3ayc0hne	155	8	injury	injury	NN
cord-006460-3ayc0hne	155	9	,	,	,
cord-006460-3ayc0hne	155	10	whereas	whereas	IN
cord-006460-3ayc0hne	155	11	immune	immune	JJ
cord-006460-3ayc0hne	155	12	excess	excess	NN
cord-006460-3ayc0hne	155	13	of	of	IN
cord-006460-3ayc0hne	155	14	the	the	DT
cord-006460-3ayc0hne	155	15	non	non	JJ
cord-006460-3ayc0hne	155	16	-	-	JJ
cord-006460-3ayc0hne	155	17	specific	specific	JJ
cord-006460-3ayc0hne	155	18	immune	immune	JJ
cord-006460-3ayc0hne	155	19	system	system	NN
cord-006460-3ayc0hne	155	20	such	such	JJ
cord-006460-3ayc0hne	155	21	as	as	IN
cord-006460-3ayc0hne	155	22	neutrophil	neutrophil	NN
cord-006460-3ayc0hne	155	23	activation	activation	NN
cord-006460-3ayc0hne	155	24	may	may	MD
cord-006460-3ayc0hne	155	25	be	be	VB
cord-006460-3ayc0hne	155	26	harmful	harmful	JJ
cord-006460-3ayc0hne	155	27	.	.	.
cord-006460-3ayc0hne	156	1	Thus	thus	RB
cord-006460-3ayc0hne	156	2	,	,	,
cord-006460-3ayc0hne	156	3	both	both	DT
cord-006460-3ayc0hne	156	4	may	may	MD
cord-006460-3ayc0hne	156	5	be	be	VB
cord-006460-3ayc0hne	156	6	at	at	IN
cord-006460-3ayc0hne	156	7	work	work	NN
cord-006460-3ayc0hne	156	8	.	.	.
cord-006460-3ayc0hne	157	1	How	how	WRB
cord-006460-3ayc0hne	157	2	do	do	VBP
cord-006460-3ayc0hne	157	3	we	-PRON-	PRP
cord-006460-3ayc0hne	157	4	sort	sort	VB
cord-006460-3ayc0hne	157	5	out	out	RP
cord-006460-3ayc0hne	157	6	which	which	WDT
cord-006460-3ayc0hne	157	7	is	be	VBZ
cord-006460-3ayc0hne	157	8	most	most	RBS
cord-006460-3ayc0hne	157	9	important	important	JJ
cord-006460-3ayc0hne	157	10	and	and	CC
cord-006460-3ayc0hne	157	11	which	which	WDT
cord-006460-3ayc0hne	157	12	should	should	MD
cord-006460-3ayc0hne	157	13	be	be	VB
cord-006460-3ayc0hne	157	14	treated	treat	VBN
cord-006460-3ayc0hne	157	15	or	or	CC
cord-006460-3ayc0hne	157	16	blocked	block	VBN
cord-006460-3ayc0hne	157	17	?	?	.
cord-006460-3ayc0hne	158	1	Another	another	DT
cord-006460-3ayc0hne	158	2	example	example	NN
cord-006460-3ayc0hne	158	3	is	be	VBZ
cord-006460-3ayc0hne	158	4	the	the	DT
cord-006460-3ayc0hne	158	5	treatment	treatment	NN
cord-006460-3ayc0hne	158	6	of	of	IN
cord-006460-3ayc0hne	158	7	patients	patient	NNS
cord-006460-3ayc0hne	158	8	with	with	IN
cord-006460-3ayc0hne	158	9	sepsis	sepsis	NN
cord-006460-3ayc0hne	158	10	syndrome	syndrome	NN
cord-006460-3ayc0hne	158	11	with	with	IN
cord-006460-3ayc0hne	158	12	a	a	DT
cord-006460-3ayc0hne	158	13	soluble	soluble	JJ
cord-006460-3ayc0hne	158	14	TNF	TNF	NNP
cord-006460-3ayc0hne	158	15	receptor	receptor	NN
cord-006460-3ayc0hne	158	16	(	(	-LRB-
cord-006460-3ayc0hne	158	17	sTNFr	sTNFr	NFP
cord-006460-3ayc0hne	158	18	)	)	-RRB-
cord-006460-3ayc0hne	158	19	[	[	-LRB-
cord-006460-3ayc0hne	158	20	35	35	CD
cord-006460-3ayc0hne	158	21	]	]	-RRB-
cord-006460-3ayc0hne	158	22	.	.	.
cord-006460-3ayc0hne	159	1	This	this	DT
cord-006460-3ayc0hne	159	2	was	be	VBD
cord-006460-3ayc0hne	159	3	a	a	DT
cord-006460-3ayc0hne	159	4	phase	phase	NN
cord-006460-3ayc0hne	159	5	II	II	NNP
cord-006460-3ayc0hne	159	6	controlled	control	VBN
cord-006460-3ayc0hne	159	7	trial	trial	NN
cord-006460-3ayc0hne	159	8	of	of	IN
cord-006460-3ayc0hne	159	9	a	a	DT
cord-006460-3ayc0hne	159	10	novel	novel	JJ
cord-006460-3ayc0hne	159	11	P75	P75	NNP
cord-006460-3ayc0hne	159	12	soluble	soluble	JJ
cord-006460-3ayc0hne	159	13	receptor	receptor	NN
cord-006460-3ayc0hne	159	14	fusion	fusion	NN
cord-006460-3ayc0hne	159	15	(	(	-LRB-
cord-006460-3ayc0hne	159	16	fused	fuse	VBN
cord-006460-3ayc0hne	159	17	with	with	IN
cord-006460-3ayc0hne	159	18	IgFc	IgFc	NNP
cord-006460-3ayc0hne	159	19	fragment	fragment	NN
cord-006460-3ayc0hne	159	20	)	)	-RRB-
cord-006460-3ayc0hne	159	21	protein	protein	NN
cord-006460-3ayc0hne	159	22	.	.	.
cord-006460-3ayc0hne	160	1	At	at	IN
cord-006460-3ayc0hne	160	2	higher	high	JJR
cord-006460-3ayc0hne	160	3	doses	dose	NNS
cord-006460-3ayc0hne	160	4	there	there	EX
cord-006460-3ayc0hne	160	5	was	be	VBD
cord-006460-3ayc0hne	160	6	increased	increase	VBN
cord-006460-3ayc0hne	160	7	mortality	mortality	NN
cord-006460-3ayc0hne	160	8	,	,	,
cord-006460-3ayc0hne	160	9	and	and	CC
cord-006460-3ayc0hne	160	10	in	in	IN
cord-006460-3ayc0hne	160	11	lower	low	JJR
cord-006460-3ayc0hne	160	12	doses	dose	NNS
cord-006460-3ayc0hne	160	13	there	there	EX
cord-006460-3ayc0hne	160	14	was	be	VBD
cord-006460-3ayc0hne	160	15	no	no	DT
cord-006460-3ayc0hne	160	16	difference	difference	NN
cord-006460-3ayc0hne	160	17	from	from	IN
cord-006460-3ayc0hne	160	18	the	the	DT
cord-006460-3ayc0hne	160	19	controls	control	NNS
cord-006460-3ayc0hne	160	20	.	.	.
cord-006460-3ayc0hne	161	1	Some	some	DT
cord-006460-3ayc0hne	161	2	have	have	VBP
cord-006460-3ayc0hne	161	3	proposed	propose	VBN
cord-006460-3ayc0hne	161	4	that	that	IN
cord-006460-3ayc0hne	161	5	physiologic	physiologic	JJ
cord-006460-3ayc0hne	161	6	improvement	improvement	NN
cord-006460-3ayc0hne	161	7	in	in	IN
cord-006460-3ayc0hne	161	8	a	a	DT
cord-006460-3ayc0hne	161	9	critically	critically	RB
cord-006460-3ayc0hne	161	10	ill	ill	JJ
cord-006460-3ayc0hne	161	11	patient	patient	NN
cord-006460-3ayc0hne	161	12	should	should	MD
cord-006460-3ayc0hne	161	13	be	be	VB
cord-006460-3ayc0hne	161	14	used	use	VBN
cord-006460-3ayc0hne	161	15	as	as	IN
cord-006460-3ayc0hne	161	16	an	an	DT
cord-006460-3ayc0hne	161	17	endpoint	endpoint	NN
cord-006460-3ayc0hne	161	18	for	for	IN
cord-006460-3ayc0hne	161	19	a	a	DT
cord-006460-3ayc0hne	161	20	clinical	clinical	JJ
cord-006460-3ayc0hne	161	21	trial	trial	NN
cord-006460-3ayc0hne	161	22	rather	rather	RB
cord-006460-3ayc0hne	161	23	than	than	IN
cord-006460-3ayc0hne	161	24	28-day	28-day	CD
cord-006460-3ayc0hne	161	25	mortality	mortality	NN
cord-006460-3ayc0hne	161	26	.	.	.
cord-006460-3ayc0hne	162	1	The	the	DT
cord-006460-3ayc0hne	162	2	problem	problem	NN
cord-006460-3ayc0hne	162	3	with	with	IN
cord-006460-3ayc0hne	162	4	this	this	DT
cord-006460-3ayc0hne	162	5	is	be	VBZ
cord-006460-3ayc0hne	162	6	,	,	,
cord-006460-3ayc0hne	162	7	what	what	WP
cord-006460-3ayc0hne	162	8	if	if	IN
cord-006460-3ayc0hne	162	9	there	there	EX
cord-006460-3ayc0hne	162	10	is	be	VBZ
cord-006460-3ayc0hne	162	11	some	some	DT
cord-006460-3ayc0hne	162	12	physiologic	physiologic	JJ
cord-006460-3ayc0hne	162	13	improvement	improvement	NN
cord-006460-3ayc0hne	162	14	such	such	JJ
cord-006460-3ayc0hne	162	15	as	as	IN
cord-006460-3ayc0hne	162	16	ventilation	ventilation	NN
cord-006460-3ayc0hne	162	17	function	function	NN
cord-006460-3ayc0hne	162	18	but	but	CC
cord-006460-3ayc0hne	162	19	the	the	DT
cord-006460-3ayc0hne	162	20	patient	patient	NN
cord-006460-3ayc0hne	162	21	dies	die	VBZ
cord-006460-3ayc0hne	162	22	anyway	anyway	RB
cord-006460-3ayc0hne	162	23	.	.	.
cord-006460-3ayc0hne	163	1	What	what	WDT
cord-006460-3ayc0hne	163	2	difference	difference	NN
cord-006460-3ayc0hne	163	3	does	do	VBZ
cord-006460-3ayc0hne	163	4	it	-PRON-	PRP
cord-006460-3ayc0hne	163	5	make	make	VB
cord-006460-3ayc0hne	163	6	?	?	.
cord-006460-3ayc0hne	164	1	Goldfarb	Goldfarb	NNP
cord-006460-3ayc0hne	164	2	[	[	-LRB-
cord-006460-3ayc0hne	164	3	36	36	CD
cord-006460-3ayc0hne	164	4	]	]	-RRB-
cord-006460-3ayc0hne	164	5	described	describe	VBN
cord-006460-3ayc0hne	164	6	investigations	investigation	NNS
cord-006460-3ayc0hne	164	7	into	into	IN
cord-006460-3ayc0hne	164	8	the	the	DT
cord-006460-3ayc0hne	164	9	polydeterminate	polydeterminate	NN
cord-006460-3ayc0hne	164	10	nature	nature	NN
cord-006460-3ayc0hne	164	11	of	of	IN
cord-006460-3ayc0hne	164	12	sepsis	sepsis	NN
cord-006460-3ayc0hne	164	13	.	.	.
cord-006460-3ayc0hne	165	1	He	-PRON-	PRP
cord-006460-3ayc0hne	165	2	stated	state	VBD
cord-006460-3ayc0hne	165	3	that	that	IN
cord-006460-3ayc0hne	165	4	,	,	,
cord-006460-3ayc0hne	165	5	"	"	``
cord-006460-3ayc0hne	165	6	A	a	DT
cord-006460-3ayc0hne	165	7	fundamental	fundamental	JJ
cord-006460-3ayc0hne	165	8	concept	concept	NN
cord-006460-3ayc0hne	165	9	of	of	IN
cord-006460-3ayc0hne	165	10	modern	modern	JJ
cord-006460-3ayc0hne	165	11	pharmacology	pharmacology	NN
cord-006460-3ayc0hne	165	12	is	be	VBZ
cord-006460-3ayc0hne	165	13	:	:	:
cord-006460-3ayc0hne	165	14	for	for	IN
cord-006460-3ayc0hne	165	15	each	each	DT
cord-006460-3ayc0hne	165	16	pathologic	pathologic	JJ
cord-006460-3ayc0hne	165	17	condition	condition	NN
cord-006460-3ayc0hne	165	18	(	(	-LRB-
cord-006460-3ayc0hne	165	19	disease	disease	NN
cord-006460-3ayc0hne	165	20	)	)	-RRB-
cord-006460-3ayc0hne	165	21	a	a	DT
cord-006460-3ayc0hne	165	22	single	single	JJ
cord-006460-3ayc0hne	165	23	pharmaceutical	pharmaceutical	NN
cord-006460-3ayc0hne	165	24	can	can	MD
cord-006460-3ayc0hne	165	25	be	be	VB
cord-006460-3ayc0hne	165	26	found	find	VBN
cord-006460-3ayc0hne	165	27	to	to	TO
cord-006460-3ayc0hne	165	28	correct	correct	VB
cord-006460-3ayc0hne	165	29	444	444	CD
cord-006460-3ayc0hne	166	1	I	-PRON-	PRP
cord-006460-3ayc0hne	166	2	believe	believe	VBP
cord-006460-3ayc0hne	166	3	we	-PRON-	PRP
cord-006460-3ayc0hne	166	4	must	must	MD
cord-006460-3ayc0hne	166	5	go	go	VB
cord-006460-3ayc0hne	166	6	back	back	RB
cord-006460-3ayc0hne	166	7	to	to	IN
cord-006460-3ayc0hne	166	8	the	the	DT
cord-006460-3ayc0hne	166	9	suggestions	suggestion	NNS
cord-006460-3ayc0hne	166	10	of	of	IN
cord-006460-3ayc0hne	166	11	Stehbens	Stehbens	NNP
cord-006460-3ayc0hne	166	12	[	[	-LRB-
cord-006460-3ayc0hne	166	13	37	37	CD
cord-006460-3ayc0hne	166	14	,	,	,
cord-006460-3ayc0hne	166	15	38	38	CD
cord-006460-3ayc0hne	166	16	]	]	-RRB-
cord-006460-3ayc0hne	166	17	.	.	.
cord-006460-3ayc0hne	167	1	He	-PRON-	PRP
cord-006460-3ayc0hne	167	2	stated	state	VBD
cord-006460-3ayc0hne	167	3	that	that	IN
cord-006460-3ayc0hne	167	4	,	,	,
cord-006460-3ayc0hne	167	5	"	"	``
cord-006460-3ayc0hne	167	6	Treatment	treatment	NN
cord-006460-3ayc0hne	167	7	of	of	IN
cord-006460-3ayc0hne	167	8	a	a	DT
cord-006460-3ayc0hne	167	9	disease	disease	NN
cord-006460-3ayc0hne	167	10	,	,	,
cord-006460-3ayc0hne	167	11	when	when	WRB
cord-006460-3ayc0hne	167	12	based	base	VBN
cord-006460-3ayc0hne	167	13	on	on	IN
cord-006460-3ayc0hne	167	14	symptoms	symptom	NNS
cord-006460-3ayc0hne	167	15	or	or	CC
cord-006460-3ayc0hne	167	16	clinical	clinical	JJ
cord-006460-3ayc0hne	167	17	manifestations	manifestation	NNS
cord-006460-3ayc0hne	167	18	is	be	VBZ
cord-006460-3ayc0hne	167	19	at	at	IN
cord-006460-3ayc0hne	167	20	best	good	JJS
cord-006460-3ayc0hne	167	21	palliative	palliative	JJ
cord-006460-3ayc0hne	167	22	and	and	CC
cord-006460-3ayc0hne	167	23	nonspecific	nonspecific	JJ
cord-006460-3ayc0hne	167	24	.	.	.
cord-006460-3ayc0hne	168	1	"	"	``
cord-006460-3ayc0hne	168	2	All	all	DT
cord-006460-3ayc0hne	168	3	of	of	IN
cord-006460-3ayc0hne	168	4	us	-PRON-	PRP
cord-006460-3ayc0hne	168	5	use	use	VBP
cord-006460-3ayc0hne	168	6	or	or	CC
cord-006460-3ayc0hne	168	7	give	give	VBP
cord-006460-3ayc0hne	168	8	therapy	therapy	NN
cord-006460-3ayc0hne	168	9	based	base	VBN
cord-006460-3ayc0hne	168	10	on	on	IN
cord-006460-3ayc0hne	168	11	symptoms	symptom	NNS
cord-006460-3ayc0hne	168	12	or	or	CC
cord-006460-3ayc0hne	168	13	clinical	clinical	JJ
cord-006460-3ayc0hne	168	14	manifestations	manifestation	NNS
cord-006460-3ayc0hne	168	15	.	.	.
cord-006460-3ayc0hne	169	1	When	when	WRB
cord-006460-3ayc0hne	169	2	we	-PRON-	PRP
cord-006460-3ayc0hne	169	3	get	get	VBP
cord-006460-3ayc0hne	169	4	a	a	DT
cord-006460-3ayc0hne	169	5	cold	cold	JJ
cord-006460-3ayc0hne	169	6	or	or	CC
cord-006460-3ayc0hne	169	7	the	the	DT
cord-006460-3ayc0hne	169	8	flu	flu	NN
cord-006460-3ayc0hne	169	9	,	,	,
cord-006460-3ayc0hne	169	10	we	-PRON-	PRP
cord-006460-3ayc0hne	169	11	may	may	MD
cord-006460-3ayc0hne	169	12	take	take	VB
cord-006460-3ayc0hne	169	13	aspirin	aspirin	NN
cord-006460-3ayc0hne	169	14	or	or	CC
cord-006460-3ayc0hne	169	15	a	a	DT
cord-006460-3ayc0hne	169	16	non	non	JJ
cord-006460-3ayc0hne	169	17	-	-	JJ
cord-006460-3ayc0hne	169	18	steroidal	steroidal	JJ
cord-006460-3ayc0hne	169	19	anti	anti	JJ
cord-006460-3ayc0hne	169	20	-	-	JJ
cord-006460-3ayc0hne	169	21	inflammatory	inflammatory	JJ
cord-006460-3ayc0hne	169	22	agent	agent	NN
cord-006460-3ayc0hne	169	23	.	.	.
cord-006460-3ayc0hne	170	1	This	this	DT
cord-006460-3ayc0hne	170	2	is	be	VBZ
cord-006460-3ayc0hne	170	3	for	for	IN
cord-006460-3ayc0hne	170	4	palliation	palliation	NN
cord-006460-3ayc0hne	170	5	,	,	,
cord-006460-3ayc0hne	170	6	to	to	TO
cord-006460-3ayc0hne	170	7	help	help	VB
cord-006460-3ayc0hne	170	8	us	-PRON-	PRP
cord-006460-3ayc0hne	170	9	feel	feel	VB
cord-006460-3ayc0hne	170	10	better	well	JJR
cord-006460-3ayc0hne	170	11	,	,	,
cord-006460-3ayc0hne	170	12	but	but	CC
cord-006460-3ayc0hne	170	13	it	-PRON-	PRP
cord-006460-3ayc0hne	170	14	will	will	MD
cord-006460-3ayc0hne	170	15	not	not	RB
cord-006460-3ayc0hne	170	16	alter	alter	VB
cord-006460-3ayc0hne	170	17	the	the	DT
cord-006460-3ayc0hne	170	18	basic	basic	JJ
cord-006460-3ayc0hne	170	19	disease	disease	NN
cord-006460-3ayc0hne	170	20	process	process	NN
cord-006460-3ayc0hne	170	21	.	.	.
cord-006460-3ayc0hne	171	1	Only	only	RB
cord-006460-3ayc0hne	171	2	specific	specific	JJ
cord-006460-3ayc0hne	171	3	treatment	treatment	NN
cord-006460-3ayc0hne	171	4	of	of	IN
cord-006460-3ayc0hne	171	5	a	a	DT
cord-006460-3ayc0hne	171	6	disease	disease	NN
cord-006460-3ayc0hne	171	7	will	will	MD
cord-006460-3ayc0hne	171	8	improve	improve	VB
cord-006460-3ayc0hne	171	9	the	the	DT
cord-006460-3ayc0hne	171	10	mortality	mortality	NN
cord-006460-3ayc0hne	171	11	and	and	CC
cord-006460-3ayc0hne	171	12	alter	alter	VB
cord-006460-3ayc0hne	171	13	the	the	DT
cord-006460-3ayc0hne	171	14	disease	disease	NN
cord-006460-3ayc0hne	171	15	process	process	NN
cord-006460-3ayc0hne	171	16	.	.	.
cord-006460-3ayc0hne	172	1	How	how	WRB
cord-006460-3ayc0hne	172	2	do	do	VBP
cord-006460-3ayc0hne	172	3	you	-PRON-	PRP
cord-006460-3ayc0hne	172	4	treat	treat	VB
cord-006460-3ayc0hne	172	5	an	an	DT
cord-006460-3ayc0hne	172	6	injury	injury	NN
cord-006460-3ayc0hne	172	7	severity	severity	NN
cord-006460-3ayc0hne	172	8	score	score	NN
cord-006460-3ayc0hne	172	9	(	(	-LRB-
cord-006460-3ayc0hne	172	10	ISS	ISS	NNP
cord-006460-3ayc0hne	172	11	)	)	-RRB-
cord-006460-3ayc0hne	172	12	of	of	IN
cord-006460-3ayc0hne	172	13	26	26	CD
cord-006460-3ayc0hne	172	14	,	,	,
cord-006460-3ayc0hne	172	15	an	an	DT
cord-006460-3ayc0hne	172	16	Apache	Apache	NNP
cord-006460-3ayc0hne	172	17	III	III	NNP
cord-006460-3ayc0hne	172	18	score	score	NN
cord-006460-3ayc0hne	172	19	of	of	IN
cord-006460-3ayc0hne	172	20	30	30	CD
cord-006460-3ayc0hne	172	21	,	,	,
cord-006460-3ayc0hne	172	22	SIRS	sirs	UH
cord-006460-3ayc0hne	172	23	,	,	,
cord-006460-3ayc0hne	172	24	MOF	MOF	NNP
cord-006460-3ayc0hne	172	25	,	,	,
cord-006460-3ayc0hne	172	26	the	the	DT
cord-006460-3ayc0hne	172	27	sepsis	sepsis	NN
cord-006460-3ayc0hne	172	28	syndrome	syndrome	NN
cord-006460-3ayc0hne	172	29	,	,	,
cord-006460-3ayc0hne	172	30	or	or	CC
cord-006460-3ayc0hne	172	31	a	a	DT
cord-006460-3ayc0hne	172	32	consensus	consensus	NN
cord-006460-3ayc0hne	172	33	conference	conference	NN
cord-006460-3ayc0hne	172	34	definition	definition	NN
cord-006460-3ayc0hne	172	35	of	of	IN
cord-006460-3ayc0hne	172	36	a	a	DT
cord-006460-3ayc0hne	172	37	human	human	JJ
cord-006460-3ayc0hne	172	38	state	state	NN
cord-006460-3ayc0hne	172	39	.	.	.
cord-006460-3ayc0hne	173	1	It	-PRON-	PRP
cord-006460-3ayc0hne	173	2	is	be	VBZ
cord-006460-3ayc0hne	173	3	impossible	impossible	JJ
cord-006460-3ayc0hne	173	4	to	to	TO
cord-006460-3ayc0hne	173	5	treat	treat	VB
cord-006460-3ayc0hne	173	6	such	such	JJ
cord-006460-3ayc0hne	173	7	abnormalities	abnormality	NNS
cord-006460-3ayc0hne	173	8	.	.	.
cord-006460-3ayc0hne	174	1	Fortunately	fortunately	RB
cord-006460-3ayc0hne	174	2	,	,	,
cord-006460-3ayc0hne	174	3	some	some	DT
cord-006460-3ayc0hne	174	4	of	of	IN
cord-006460-3ayc0hne	174	5	the	the	DT
cord-006460-3ayc0hne	174	6	gurus	guru	NNS
cord-006460-3ayc0hne	174	7	of	of	IN
cord-006460-3ayc0hne	174	8	critical	critical	JJ
cord-006460-3ayc0hne	174	9	care	care	NN
cord-006460-3ayc0hne	174	10	agree	agree	VBP
cord-006460-3ayc0hne	174	11	that	that	IN
cord-006460-3ayc0hne	174	12	it	-PRON-	PRP
cord-006460-3ayc0hne	174	13	is	be	VBZ
cord-006460-3ayc0hne	174	14	time	time	NN
cord-006460-3ayc0hne	174	15	for	for	IN
cord-006460-3ayc0hne	174	16	a	a	DT
cord-006460-3ayc0hne	174	17	reevaluation	reevaluation	NN
cord-006460-3ayc0hne	174	18	of	of	IN
cord-006460-3ayc0hne	174	19	these	these	DT
cord-006460-3ayc0hne	174	20	definitions	definition	NNS
cord-006460-3ayc0hne	174	21	[	[	-LRB-
cord-006460-3ayc0hne	174	22	39	39	CD
cord-006460-3ayc0hne	174	23	]	]	-RRB-
cord-006460-3ayc0hne	174	24	.	.	.
cord-006460-3ayc0hne	175	1	Solbach	Solbach	NNP
cord-006460-3ayc0hne	175	2	et	et	FW
cord-006460-3ayc0hne	175	3	al	al	NNP
cord-006460-3ayc0hne	175	4	.	.	.
cord-006460-3ayc0hne	176	1	[	[	-LRB-
cord-006460-3ayc0hne	176	2	40	40	CD
cord-006460-3ayc0hne	176	3	]	]	-RRB-
cord-006460-3ayc0hne	176	4	wrote	write	VBD
cord-006460-3ayc0hne	176	5	that	that	IN
cord-006460-3ayc0hne	176	6	"	"	``
cord-006460-3ayc0hne	176	7	lymphocytes	lymphocyte	NNS
cord-006460-3ayc0hne	176	8	play	play	VBP
cord-006460-3ayc0hne	176	9	the	the	DT
cord-006460-3ayc0hne	176	10	music	music	NN
cord-006460-3ayc0hne	176	11	,	,	,
cord-006460-3ayc0hne	176	12	but	but	CC
cord-006460-3ayc0hne	176	13	the	the	DT
cord-006460-3ayc0hne	176	14	macrophages	macrophage	NNS
cord-006460-3ayc0hne	176	15	call	call	VBP
cord-006460-3ayc0hne	176	16	the	the	DT
cord-006460-3ayc0hne	176	17	tune	tune	NN
cord-006460-3ayc0hne	176	18	.	.	.
cord-006460-3ayc0hne	177	1	"	"	``
cord-006460-3ayc0hne	177	2	They	-PRON-	PRP
cord-006460-3ayc0hne	177	3	stated	state	VBD
cord-006460-3ayc0hne	177	4	that	that	IN
cord-006460-3ayc0hne	177	5	,	,	,
cord-006460-3ayc0hne	177	6	"	"	``
cord-006460-3ayc0hne	177	7	Dealing	deal	VBG
cord-006460-3ayc0hne	177	8	with	with	IN
cord-006460-3ayc0hne	177	9	a	a	DT
cord-006460-3ayc0hne	177	10	single	single	JJ
cord-006460-3ayc0hne	177	11	cytokine	cytokine	NN
cord-006460-3ayc0hne	177	12	on	on	IN
cord-006460-3ayc0hne	177	13	an	an	DT
cord-006460-3ayc0hne	177	14	isolated	isolated	JJ
cord-006460-3ayc0hne	177	15	population	population	NN
cord-006460-3ayc0hne	177	16	of	of	IN
cord-006460-3ayc0hne	177	17	cells	cell	NNS
cord-006460-3ayc0hne	177	18	(	(	-LRB-
cord-006460-3ayc0hne	177	19	or	or	CC
cord-006460-3ayc0hne	177	20	an	an	DT
cord-006460-3ayc0hne	177	21	organism	organism	NN
cord-006460-3ayc0hne	177	22	)	)	-RRB-
cord-006460-3ayc0hne	177	23	may	may	MD
cord-006460-3ayc0hne	177	24	be	be	VB
cord-006460-3ayc0hne	177	25	a	a	DT
cord-006460-3ayc0hne	177	26	gross	gross	JJ
cord-006460-3ayc0hne	177	27	oversimplification	oversimplification	NN
cord-006460-3ayc0hne	177	28	of	of	IN
cord-006460-3ayc0hne	177	29	events	event	NNS
cord-006460-3ayc0hne	177	30	in	in	IN
cord-006460-3ayc0hne	177	31	vivo	vivo	NN
cord-006460-3ayc0hne	177	32	.	.	.
cord-006460-3ayc0hne	178	1	"	"	``
cord-006460-3ayc0hne	178	2	I	-PRON-	PRP
cord-006460-3ayc0hne	178	3	believe	believe	VBP
cord-006460-3ayc0hne	178	4	that	that	IN
cord-006460-3ayc0hne	178	5	they	-PRON-	PRP
cord-006460-3ayc0hne	178	6	have	have	VBP
cord-006460-3ayc0hne	178	7	hit	hit	VBN
cord-006460-3ayc0hne	178	8	the	the	DT
cord-006460-3ayc0hne	178	9	nail	nail	NN
cord-006460-3ayc0hne	178	10	on	on	IN
cord-006460-3ayc0hne	178	11	the	the	DT
cord-006460-3ayc0hne	178	12	head	head	NN
cord-006460-3ayc0hne	178	13	.	.	.
cord-006460-3ayc0hne	179	1	I	-PRON-	PRP
cord-006460-3ayc0hne	179	2	have	have	VBP
cord-006460-3ayc0hne	179	3	now	now	RB
cord-006460-3ayc0hne	179	4	reviewed	review	VBN
cord-006460-3ayc0hne	179	5	the	the	DT
cord-006460-3ayc0hne	179	6	third	third	JJ
cord-006460-3ayc0hne	179	7	reason	reason	NN
cord-006460-3ayc0hne	179	8	for	for	IN
cord-006460-3ayc0hne	179	9	the	the	DT
cord-006460-3ayc0hne	179	10	discrepancy	discrepancy	NN
cord-006460-3ayc0hne	179	11	between	between	IN
cord-006460-3ayc0hne	179	12	excellent	excellent	JJ
cord-006460-3ayc0hne	179	13	science	science	NN
cord-006460-3ayc0hne	179	14	and	and	CC
cord-006460-3ayc0hne	179	15	patient	patient	NN
cord-006460-3ayc0hne	179	16	care	care	NN
cord-006460-3ayc0hne	179	17	.	.	.
cord-006460-3ayc0hne	180	1	I	-PRON-	PRP
cord-006460-3ayc0hne	180	2	will	will	MD
cord-006460-3ayc0hne	180	3	now	now	RB
cord-006460-3ayc0hne	180	4	go	go	VB
cord-006460-3ayc0hne	180	5	back	back	RB
cord-006460-3ayc0hne	180	6	to	to	IN
cord-006460-3ayc0hne	180	7	reasons	reason	NNS
cord-006460-3ayc0hne	180	8	1	1	CD
cord-006460-3ayc0hne	180	9	and	and	CC
cord-006460-3ayc0hne	180	10	2	2	CD
cord-006460-3ayc0hne	180	11	.	.	.
cord-006460-3ayc0hne	181	1	First	first	RB
cord-006460-3ayc0hne	181	2	,	,	,
cord-006460-3ayc0hne	181	3	the	the	DT
cord-006460-3ayc0hne	181	4	differences	difference	NNS
cord-006460-3ayc0hne	181	5	between	between	IN
cord-006460-3ayc0hne	181	6	individuals	individual	NNS
cord-006460-3ayc0hne	181	7	.	.	.
cord-006460-3ayc0hne	182	1	These	these	DT
cord-006460-3ayc0hne	182	2	variations	variation	NNS
cord-006460-3ayc0hne	182	3	include	include	VBP
cord-006460-3ayc0hne	182	4	:	:	:
cord-006460-3ayc0hne	182	5	1	1	CD
cord-006460-3ayc0hne	182	6	.	.	.
cord-006460-3ayc0hne	183	1	Genetic	genetic	JJ
cord-006460-3ayc0hne	183	2	differences	difference	NNS
cord-006460-3ayc0hne	183	3	in	in	IN
cord-006460-3ayc0hne	183	4	cytokine	cytokine	JJ
cord-006460-3ayc0hne	183	5	response	response	NN
cord-006460-3ayc0hne	183	6	to	to	IN
cord-006460-3ayc0hne	183	7	sepsis	sepsis	NN
cord-006460-3ayc0hne	183	8	,	,	,
cord-006460-3ayc0hne	183	9	including	include	VBG
cord-006460-3ayc0hne	183	10	DNA	dna	NN
cord-006460-3ayc0hne	183	11	polymorphism	polymorphism	NN
cord-006460-3ayc0hne	183	12	of	of	IN
cord-006460-3ayc0hne	183	13	tumor	tumor	NN
cord-006460-3ayc0hne	183	14	necrosis	necrosis	NN
cord-006460-3ayc0hne	183	15	factor	factor	NN
cord-006460-3ayc0hne	183	16	(	(	-LRB-
cord-006460-3ayc0hne	183	17	TNF	TNF	NNP
cord-006460-3ayc0hne	183	18	)	)	-RRB-
cord-006460-3ayc0hne	183	19	,	,	,
cord-006460-3ayc0hne	183	20	interleukin	interleukin	FW
cord-006460-3ayc0hne	183	21	(	(	-LRB-
cord-006460-3ayc0hne	183	22	IL	IL	NNP
cord-006460-3ayc0hne	183	23	)	)	-RRB-
cord-006460-3ayc0hne	183	24	-1	-1	.
cord-006460-3ayc0hne	184	1	and	and	CC
cord-006460-3ayc0hne	184	2	IL-1ra	IL-1ra	NNP
cord-006460-3ayc0hne	184	3	.	.	.
cord-006460-3ayc0hne	185	1	Some	some	DT
cord-006460-3ayc0hne	185	2	seem	seem	VBP
cord-006460-3ayc0hne	185	3	to	to	TO
cord-006460-3ayc0hne	185	4	protect	protect	VB
cord-006460-3ayc0hne	185	5	,	,	,
cord-006460-3ayc0hne	185	6	while	while	IN
cord-006460-3ayc0hne	185	7	others	other	NNS
cord-006460-3ayc0hne	185	8	are	be	VBP
cord-006460-3ayc0hne	185	9	associated	associate	VBN
cord-006460-3ayc0hne	185	10	with	with	IN
cord-006460-3ayc0hne	185	11	a	a	DT
cord-006460-3ayc0hne	185	12	poor	poor	JJ
cord-006460-3ayc0hne	185	13	prognosis	prognosis	NN
cord-006460-3ayc0hne	185	14	.	.	.
cord-006460-3ayc0hne	186	1	Some	some	DT
cord-006460-3ayc0hne	186	2	of	of	IN
cord-006460-3ayc0hne	186	3	these	these	DT
cord-006460-3ayc0hne	186	4	have	have	VBP
cord-006460-3ayc0hne	186	5	been	be	VBN
cord-006460-3ayc0hne	186	6	described	describe	VBN
cord-006460-3ayc0hne	186	7	by	by	IN
cord-006460-3ayc0hne	186	8	Zehnbauer	Zehnbauer	NNP
cord-006460-3ayc0hne	186	9	et	et	NNP
cord-006460-3ayc0hne	186	10	al	al	NNP
cord-006460-3ayc0hne	186	11	.	.	.
cord-006460-3ayc0hne	187	1	[	[	-LRB-
cord-006460-3ayc0hne	187	2	41	41	CD
cord-006460-3ayc0hne	187	3	]	]	-RRB-
cord-006460-3ayc0hne	187	4	.	.	.
cord-006460-3ayc0hne	188	1	An	an	DT
cord-006460-3ayc0hne	188	2	IL-1ra	IL-1ra	NNP
cord-006460-3ayc0hne	188	3	polymorphism	polymorphism	NN
cord-006460-3ayc0hne	188	4	may	may	MD
cord-006460-3ayc0hne	188	5	increase	increase	VB
cord-006460-3ayc0hne	188	6	susceptibility	susceptibility	NN
cord-006460-3ayc0hne	188	7	to	to	IN
cord-006460-3ayc0hne	188	8	sepsis	sepsis	NN
cord-006460-3ayc0hne	188	9	[	[	-LRB-
cord-006460-3ayc0hne	188	10	42	42	CD
cord-006460-3ayc0hne	188	11	]	]	-RRB-
cord-006460-3ayc0hne	188	12	.	.	.
cord-006460-3ayc0hne	189	1	There	there	EX
cord-006460-3ayc0hne	189	2	is	be	VBZ
cord-006460-3ayc0hne	189	3	the	the	DT
cord-006460-3ayc0hne	189	4	possibility	possibility	NN
cord-006460-3ayc0hne	189	5	of	of	IN
cord-006460-3ayc0hne	189	6	another	another	DT
cord-006460-3ayc0hne	189	7	IL-1	IL-1	NNP
cord-006460-3ayc0hne	189	8	predisposition	predisposition	NN
cord-006460-3ayc0hne	189	9	to	to	IN
cord-006460-3ayc0hne	189	10	sepsis	sepsis	NN
cord-006460-3ayc0hne	189	11	that	that	WDT
cord-006460-3ayc0hne	189	12	may	may	MD
cord-006460-3ayc0hne	189	13	also	also	RB
cord-006460-3ayc0hne	189	14	vary	vary	VB
cord-006460-3ayc0hne	189	15	in	in	IN
cord-006460-3ayc0hne	189	16	populations	population	NNS
cord-006460-3ayc0hne	189	17	in	in	IN
cord-006460-3ayc0hne	189	18	the	the	DT
cord-006460-3ayc0hne	189	19	UK	UK	NNP
cord-006460-3ayc0hne	189	20	from	from	IN
cord-006460-3ayc0hne	189	21	those	those	DT
cord-006460-3ayc0hne	189	22	in	in	IN
cord-006460-3ayc0hne	189	23	Australia	Australia	NNP
cord-006460-3ayc0hne	189	24	[	[	-LRB-
cord-006460-3ayc0hne	189	25	43	43	CD
cord-006460-3ayc0hne	189	26	]	]	-RRB-
cord-006460-3ayc0hne	189	27	.	.	.
cord-006460-3ayc0hne	190	1	A	a	DT
cord-006460-3ayc0hne	190	2	TNF2	tnf2	CD
cord-006460-3ayc0hne	190	3	allele	allele	NN
cord-006460-3ayc0hne	190	4	is	be	VBZ
cord-006460-3ayc0hne	190	5	strongly	strongly	RB
cord-006460-3ayc0hne	190	6	associated	associate	VBN
cord-006460-3ayc0hne	190	7	with	with	IN
cord-006460-3ayc0hne	190	8	death	death	NN
cord-006460-3ayc0hne	190	9	from	from	IN
cord-006460-3ayc0hne	190	10	septic	septic	JJ
cord-006460-3ayc0hne	190	11	shock	shock	NN
cord-006460-3ayc0hne	190	12	[	[	-LRB-
cord-006460-3ayc0hne	190	13	44	44	CD
cord-006460-3ayc0hne	190	14	]	]	-RRB-
cord-006460-3ayc0hne	190	15	and	and	CC
cord-006460-3ayc0hne	190	16	another	another	DT
cord-006460-3ayc0hne	190	17	TNFb	tnfb	NN
cord-006460-3ayc0hne	190	18	gene	gene	NN
cord-006460-3ayc0hne	190	19	is	be	VBZ
cord-006460-3ayc0hne	190	20	associated	associate	VBN
cord-006460-3ayc0hne	190	21	with	with	IN
cord-006460-3ayc0hne	190	22	sepsis	sepsis	NN
cord-006460-3ayc0hne	190	23	in	in	IN
cord-006460-3ayc0hne	190	24	trauma	trauma	NN
cord-006460-3ayc0hne	190	25	patients	patient	NNS
cord-006460-3ayc0hne	190	26	[	[	-LRB-
cord-006460-3ayc0hne	190	27	45	45	CD
cord-006460-3ayc0hne	190	28	]	]	-RRB-
cord-006460-3ayc0hne	190	29	.	.	.
cord-006460-3ayc0hne	191	1	2	2	LS
cord-006460-3ayc0hne	191	2	.	.	.
cord-006460-3ayc0hne	192	1	There	there	EX
cord-006460-3ayc0hne	192	2	are	be	VBP
cord-006460-3ayc0hne	192	3	differences	difference	NNS
cord-006460-3ayc0hne	192	4	in	in	IN
cord-006460-3ayc0hne	192	5	preoperative	preoperative	JJ
cord-006460-3ayc0hne	192	6	,	,	,
cord-006460-3ayc0hne	192	7	pre	pre	JJ
cord-006460-3ayc0hne	192	8	-	-	JJ
cord-006460-3ayc0hne	192	9	illness	illness	JJ
cord-006460-3ayc0hne	192	10	immunity	immunity	NN
cord-006460-3ayc0hne	192	11	and	and	CC
cord-006460-3ayc0hne	192	12	prior	prior	JJ
cord-006460-3ayc0hne	192	13	immune	immune	JJ
cord-006460-3ayc0hne	192	14	history	history	NN
cord-006460-3ayc0hne	192	15	.	.	.
cord-006460-3ayc0hne	193	1	An	an	DT
cord-006460-3ayc0hne	193	2	example	example	NN
cord-006460-3ayc0hne	193	3	of	of	IN
cord-006460-3ayc0hne	193	4	this	this	DT
cord-006460-3ayc0hne	193	5	was	be	VBD
cord-006460-3ayc0hne	193	6	described	describe	VBN
cord-006460-3ayc0hne	193	7	by	by	IN
cord-006460-3ayc0hne	193	8	Bennett	Bennett	NNP
cord-006460-3ayc0hne	193	9	-	-	HYPH
cord-006460-3ayc0hne	193	10	Guererro	Guererro	NNP
cord-006460-3ayc0hne	193	11	et	et	FW
cord-006460-3ayc0hne	193	12	al	al	NNP
cord-006460-3ayc0hne	193	13	.	.	.
cord-006460-3ayc0hne	194	1	[	[	-LRB-
cord-006460-3ayc0hne	194	2	46	46	CD
cord-006460-3ayc0hne	194	3	]	]	-RRB-
cord-006460-3ayc0hne	194	4	,	,	,
cord-006460-3ayc0hne	194	5	who	who	WP
cord-006460-3ayc0hne	194	6	measured	measure	VBD
cord-006460-3ayc0hne	194	7	the	the	DT
cord-006460-3ayc0hne	194	8	endotoxin	endotoxin	NN
cord-006460-3ayc0hne	194	9	core	core	NN
cord-006460-3ayc0hne	194	10	antibody	antibody	NN
cord-006460-3ayc0hne	194	11	Endocab	Endocab	NNP
cord-006460-3ayc0hne	194	12	.	.	.
cord-006460-3ayc0hne	195	1	A	a	DT
cord-006460-3ayc0hne	195	2	low	low	JJ
cord-006460-3ayc0hne	195	3	preoperative	preoperative	JJ
cord-006460-3ayc0hne	195	4	level	level	NN
cord-006460-3ayc0hne	195	5	of	of	IN
cord-006460-3ayc0hne	195	6	Endocab	Endocab	NNP
cord-006460-3ayc0hne	195	7	in	in	IN
cord-006460-3ayc0hne	195	8	patients	patient	NNS
cord-006460-3ayc0hne	195	9	undergoing	undergo	VBG
cord-006460-3ayc0hne	195	10	cardiac	cardiac	JJ
cord-006460-3ayc0hne	195	11	operations	operation	NNS
cord-006460-3ayc0hne	195	12	predicted	predict	VBD
cord-006460-3ayc0hne	195	13	an	an	DT
cord-006460-3ayc0hne	195	14	adverse	adverse	JJ
cord-006460-3ayc0hne	195	15	outcome	outcome	NN
cord-006460-3ayc0hne	195	16	,	,	,
cord-006460-3ayc0hne	195	17	whereas	whereas	IN
cord-006460-3ayc0hne	195	18	high	high	JJ
cord-006460-3ayc0hne	195	19	levels	level	NNS
cord-006460-3ayc0hne	195	20	suggesting	suggest	VBG
cord-006460-3ayc0hne	195	21	previous	previous	JJ
cord-006460-3ayc0hne	195	22	expo	expo	NN
cord-006460-3ayc0hne	195	23	-	-	:
cord-006460-3ayc0hne	195	24	sure	sure	JJ
cord-006460-3ayc0hne	195	25	to	to	IN
cord-006460-3ayc0hne	195	26	either	either	CC
cord-006460-3ayc0hne	195	27	gram	gram	NN
cord-006460-3ayc0hne	195	28	-	-	HYPH
cord-006460-3ayc0hne	195	29	negative	negative	JJ
cord-006460-3ayc0hne	195	30	bacteria	bacteria	NNS
cord-006460-3ayc0hne	195	31	or	or	CC
cord-006460-3ayc0hne	195	32	endotoxin	endotoxin	NN
cord-006460-3ayc0hne	195	33	predicted	predict	VBD
cord-006460-3ayc0hne	195	34	an	an	DT
cord-006460-3ayc0hne	195	35	improved	improved	JJ
cord-006460-3ayc0hne	195	36	outcome	outcome	NN
cord-006460-3ayc0hne	195	37	.	.	.
cord-006460-3ayc0hne	196	1	This	this	DT
cord-006460-3ayc0hne	196	2	finding	finding	NN
cord-006460-3ayc0hne	196	3	has	have	VBZ
cord-006460-3ayc0hne	196	4	been	be	VBN
cord-006460-3ayc0hne	196	5	confirmed	confirm	VBN
cord-006460-3ayc0hne	196	6	by	by	IN
cord-006460-3ayc0hne	196	7	Hamilton	Hamilton	NNP
cord-006460-3ayc0hne	196	8	-	-	HYPH
cord-006460-3ayc0hne	196	9	Davies	Davies	NNP
cord-006460-3ayc0hne	196	10	et	et	NNP
cord-006460-3ayc0hne	196	11	al	al	NNP
cord-006460-3ayc0hne	196	12	.	.	.
cord-006460-3ayc0hne	197	1	[	[	-LRB-
cord-006460-3ayc0hne	197	2	47	47	CD
cord-006460-3ayc0hne	197	3	]	]	-RRB-
cord-006460-3ayc0hne	197	4	.	.	.
cord-006460-3ayc0hne	198	1	3	3	LS
cord-006460-3ayc0hne	198	2	.	.	.
cord-006460-3ayc0hne	199	1	There	there	EX
cord-006460-3ayc0hne	199	2	are	be	VBP
cord-006460-3ayc0hne	199	3	male	male	JJ
cord-006460-3ayc0hne	199	4	/	/	SYM
cord-006460-3ayc0hne	199	5	female	female	JJ
cord-006460-3ayc0hne	199	6	gender	gender	NN
cord-006460-3ayc0hne	199	7	differences	difference	NNS
cord-006460-3ayc0hne	199	8	in	in	IN
cord-006460-3ayc0hne	199	9	both	both	DT
cord-006460-3ayc0hne	199	10	animals	animal	NNS
cord-006460-3ayc0hne	199	11	and	and	CC
cord-006460-3ayc0hne	199	12	patients	patient	NNS
cord-006460-3ayc0hne	199	13	as	as	IN
cord-006460-3ayc0hne	199	14	described	describe	VBN
cord-006460-3ayc0hne	199	15	by	by	IN
cord-006460-3ayc0hne	199	16	Chaudry	Chaudry	NNP
cord-006460-3ayc0hne	199	17	et	et	NNP
cord-006460-3ayc0hne	199	18	al	al	NNP
cord-006460-3ayc0hne	199	19	.	.	.
cord-006460-3ayc0hne	200	1	[	[	-LRB-
cord-006460-3ayc0hne	200	2	48	48	CD
cord-006460-3ayc0hne	200	3	]	]	-RRB-
cord-006460-3ayc0hne	200	4	and	and	CC
cord-006460-3ayc0hne	200	5	others	other	NNS
cord-006460-3ayc0hne	200	6	.	.	.
cord-006460-3ayc0hne	201	1	4	4	LS
cord-006460-3ayc0hne	201	2	.	.	.
cord-006460-3ayc0hne	202	1	The	the	DT
cord-006460-3ayc0hne	202	2	age	age	NN
cord-006460-3ayc0hne	202	3	of	of	IN
cord-006460-3ayc0hne	202	4	the	the	DT
cord-006460-3ayc0hne	202	5	patient	patient	NN
cord-006460-3ayc0hne	202	6	makes	make	VBZ
cord-006460-3ayc0hne	202	7	a	a	DT
cord-006460-3ayc0hne	202	8	big	big	JJ
cord-006460-3ayc0hne	202	9	difference	difference	NN
cord-006460-3ayc0hne	202	10	.	.	.
cord-006460-3ayc0hne	203	1	5	5	LS
cord-006460-3ayc0hne	203	2	.	.	.
cord-006460-3ayc0hne	204	1	Prior	prior	JJ
cord-006460-3ayc0hne	204	2	illness	illness	NN
cord-006460-3ayc0hne	204	3	,	,	,
cord-006460-3ayc0hne	204	4	such	such	JJ
cord-006460-3ayc0hne	204	5	as	as	IN
cord-006460-3ayc0hne	204	6	chronic	chronic	JJ
cord-006460-3ayc0hne	204	7	obstructive	obstructive	JJ
cord-006460-3ayc0hne	204	8	pulmonary	pulmonary	JJ
cord-006460-3ayc0hne	204	9	disease	disease	NN
cord-006460-3ayc0hne	204	10	(	(	-LRB-
cord-006460-3ayc0hne	204	11	COPD	COPD	NNP
cord-006460-3ayc0hne	204	12	)	)	-RRB-
cord-006460-3ayc0hne	204	13	,	,	,
cord-006460-3ayc0hne	204	14	coronary	coronary	JJ
cord-006460-3ayc0hne	204	15	artery	artery	NN
cord-006460-3ayc0hne	204	16	disease	disease	NN
cord-006460-3ayc0hne	204	17	,	,	,
cord-006460-3ayc0hne	204	18	etc	etc	FW
cord-006460-3ayc0hne	204	19	.	.	FW
cord-006460-3ayc0hne	204	20	,	,	,
cord-006460-3ayc0hne	204	21	make	make	VB
cord-006460-3ayc0hne	204	22	a	a	DT
cord-006460-3ayc0hne	204	23	difference	difference	NN
cord-006460-3ayc0hne	204	24	.	.	.
cord-006460-3ayc0hne	205	1	6	6	LS
cord-006460-3ayc0hne	205	2	.	.	.
cord-006460-3ayc0hne	206	1	Lifestyle	lifestyle	NN
cord-006460-3ayc0hne	206	2	,	,	,
cord-006460-3ayc0hne	206	3	obesity	obesity	NN
cord-006460-3ayc0hne	206	4	,	,	,
cord-006460-3ayc0hne	206	5	poor	poor	JJ
cord-006460-3ayc0hne	206	6	nutrition	nutrition	NN
cord-006460-3ayc0hne	206	7	,	,	,
cord-006460-3ayc0hne	206	8	lack	lack	NN
cord-006460-3ayc0hne	206	9	of	of	IN
cord-006460-3ayc0hne	206	10	exercise	exercise	NN
cord-006460-3ayc0hne	206	11	,	,	,
cord-006460-3ayc0hne	206	12	etc	etc	FW
cord-006460-3ayc0hne	206	13	.	.	.
cord-006460-3ayc0hne	207	1	are	be	VBP
cord-006460-3ayc0hne	207	2	all	all	DT
cord-006460-3ayc0hne	207	3	factors	factor	NNS
cord-006460-3ayc0hne	207	4	!	!	.
cord-006460-3ayc0hne	208	1	There	there	EX
cord-006460-3ayc0hne	208	2	are	be	VBP
cord-006460-3ayc0hne	208	3	other	other	JJ
cord-006460-3ayc0hne	208	4	variations	variation	NNS
cord-006460-3ayc0hne	208	5	in	in	IN
cord-006460-3ayc0hne	208	6	patients	patient	NNS
cord-006460-3ayc0hne	208	7	,	,	,
cord-006460-3ayc0hne	208	8	including	include	VBG
cord-006460-3ayc0hne	208	9	cytokine	cytokine	NN
cord-006460-3ayc0hne	208	10	pleiotropy	pleiotropy	NN
cord-006460-3ayc0hne	208	11	and	and	CC
cord-006460-3ayc0hne	208	12	redundancy	redundancy	NN
cord-006460-3ayc0hne	208	13	,	,	,
cord-006460-3ayc0hne	208	14	as	as	IN
cord-006460-3ayc0hne	208	15	described	describe	VBN
cord-006460-3ayc0hne	208	16	by	by	IN
cord-006460-3ayc0hne	208	17	Sánchez	Sánchez	NNP
cord-006460-3ayc0hne	208	18	-	-	HYPH
cord-006460-3ayc0hne	208	19	Cuenca	Cuenca	NNP
cord-006460-3ayc0hne	208	20	et	et	FW
cord-006460-3ayc0hne	208	21	al	al	NNP
cord-006460-3ayc0hne	208	22	.	.	.
cord-006460-3ayc0hne	209	1	[	[	-LRB-
cord-006460-3ayc0hne	209	2	49	49	CD
cord-006460-3ayc0hne	209	3	]	]	-RRB-
cord-006460-3ayc0hne	209	4	.	.	.
cord-006460-3ayc0hne	210	1	Examples	example	NNS
cord-006460-3ayc0hne	210	2	of	of	IN
cord-006460-3ayc0hne	210	3	this	this	DT
cord-006460-3ayc0hne	210	4	are	be	VBP
cord-006460-3ayc0hne	210	5	that	that	IN
cord-006460-3ayc0hne	210	6	the	the	DT
cord-006460-3ayc0hne	210	7	blocking	blocking	NN
cord-006460-3ayc0hne	210	8	of	of	IN
cord-006460-3ayc0hne	210	9	TNF	TNF	NNP
cord-006460-3ayc0hne	210	10	-	-	:
cord-006460-3ayc0hne	210	11	does	do	VBZ
cord-006460-3ayc0hne	210	12	not	not	RB
cord-006460-3ayc0hne	210	13	alter	alter	VB
cord-006460-3ayc0hne	210	14	other	other	JJ
cord-006460-3ayc0hne	210	15	products	product	NNS
cord-006460-3ayc0hne	210	16	[	[	-LRB-
cord-006460-3ayc0hne	210	17	50	50	CD
cord-006460-3ayc0hne	210	18	]	]	-RRB-
cord-006460-3ayc0hne	210	19	,	,	,
cord-006460-3ayc0hne	210	20	the	the	DT
cord-006460-3ayc0hne	210	21	polymorphisms	polymorphism	NNS
cord-006460-3ayc0hne	210	22	of	of	IN
cord-006460-3ayc0hne	210	23	interferon	interferon	NN
cord-006460-3ayc0hne	210	24	-	-	HYPH
cord-006460-3ayc0hne	210	25	microsatellites	microsatellite	NNS
cord-006460-3ayc0hne	210	26	[	[	-LRB-
cord-006460-3ayc0hne	210	27	51	51	CD
cord-006460-3ayc0hne	210	28	]	]	-RRB-
cord-006460-3ayc0hne	210	29	,	,	,
cord-006460-3ayc0hne	210	30	discordant	discordant	JJ
cord-006460-3ayc0hne	210	31	TNF	TNF	NNP
cord-006460-3ayc0hne	210	32	-	-	HYPH
cord-006460-3ayc0hne	210	33	super	super	NNP
cord-006460-3ayc0hne	210	34	family	family	NN
cord-006460-3ayc0hne	210	35	gene	gene	NN
cord-006460-3ayc0hne	210	36	expression	expression	NN
cord-006460-3ayc0hne	210	37	[	[	-LRB-
cord-006460-3ayc0hne	210	38	52	52	CD
cord-006460-3ayc0hne	210	39	]	]	-RRB-
cord-006460-3ayc0hne	210	40	,	,	,
cord-006460-3ayc0hne	210	41	IL-1	IL-1	NNP
cord-006460-3ayc0hne	210	42	receptor	receptor	NN
cord-006460-3ayc0hne	210	43	antagonist	antagonist	NN
cord-006460-3ayc0hne	210	44	polymorphism	polymorphism	NN
cord-006460-3ayc0hne	210	45	[	[	-LRB-
cord-006460-3ayc0hne	210	46	42	42	CD
cord-006460-3ayc0hne	210	47	]	]	-RRB-
cord-006460-3ayc0hne	210	48	,	,	,
cord-006460-3ayc0hne	210	49	leukocyte	leukocyte	NN
cord-006460-3ayc0hne	210	50	receptors	receptor	NNS
cord-006460-3ayc0hne	210	51	for	for	IN
cord-006460-3ayc0hne	210	52	TNF	tnf	NN
cord-006460-3ayc0hne	210	53	differences	difference	NNS
cord-006460-3ayc0hne	210	54	[	[	-LRB-
cord-006460-3ayc0hne	210	55	53	53	CD
cord-006460-3ayc0hne	210	56	]	]	-RRB-
cord-006460-3ayc0hne	210	57	,	,	,
cord-006460-3ayc0hne	210	58	different	different	JJ
cord-006460-3ayc0hne	210	59	polymorphic	polymorphic	JJ
cord-006460-3ayc0hne	210	60	heat	heat	NN
cord-006460-3ayc0hne	210	61	shock	shock	NN
cord-006460-3ayc0hne	210	62	proteins	protein	NNS
cord-006460-3ayc0hne	210	63	(	(	-LRB-
cord-006460-3ayc0hne	210	64	HSPs	HSPs	NNP
cord-006460-3ayc0hne	210	65	)	)	-RRB-
cord-006460-3ayc0hne	210	66	and	and	CC
cord-006460-3ayc0hne	210	67	variations	variation	NNS
cord-006460-3ayc0hne	210	68	[	[	-LRB-
cord-006460-3ayc0hne	210	69	54	54	CD
cord-006460-3ayc0hne	210	70	]	]	-RRB-
cord-006460-3ayc0hne	210	71	,	,	,
cord-006460-3ayc0hne	210	72	and	and	CC
cord-006460-3ayc0hne	210	73	variations	variation	NNS
cord-006460-3ayc0hne	210	74	in	in	IN
cord-006460-3ayc0hne	210	75	different	different	JJ
cord-006460-3ayc0hne	210	76	populations	population	NNS
cord-006460-3ayc0hne	210	77	,	,	,
cord-006460-3ayc0hne	210	78	such	such	JJ
cord-006460-3ayc0hne	210	79	as	as	IN
cord-006460-3ayc0hne	210	80	the	the	DT
cord-006460-3ayc0hne	210	81	difference	difference	NN
cord-006460-3ayc0hne	210	82	in	in	IN
cord-006460-3ayc0hne	210	83	UK	UK	NNP
cord-006460-3ayc0hne	210	84	and	and	CC
cord-006460-3ayc0hne	210	85	Australian	australian	JJ
cord-006460-3ayc0hne	210	86	population	population	NN
cord-006460-3ayc0hne	210	87	responses	response	NNS
cord-006460-3ayc0hne	210	88	to	to	IN
cord-006460-3ayc0hne	210	89	various	various	JJ
cord-006460-3ayc0hne	210	90	substances	substance	NNS
cord-006460-3ayc0hne	210	91	[	[	-LRB-
cord-006460-3ayc0hne	210	92	43	43	CD
cord-006460-3ayc0hne	210	93	]	]	-RRB-
cord-006460-3ayc0hne	210	94	.	.	.
cord-006460-3ayc0hne	211	1	Aasen	Aasen	NNP
cord-006460-3ayc0hne	211	2	et	et	NNP
cord-006460-3ayc0hne	211	3	al	al	NNP
cord-006460-3ayc0hne	211	4	.	.	.
cord-006460-3ayc0hne	212	1	[	[	-LRB-
cord-006460-3ayc0hne	212	2	55	55	CD
cord-006460-3ayc0hne	212	3	]	]	-RRB-
cord-006460-3ayc0hne	212	4	studied	study	VBD
cord-006460-3ayc0hne	212	5	the	the	DT
cord-006460-3ayc0hne	212	6	immunologic	immunologic	JJ
cord-006460-3ayc0hne	212	7	and	and	CC
cord-006460-3ayc0hne	212	8	inflammatory	inflammatory	JJ
cord-006460-3ayc0hne	212	9	consequences	consequence	NNS
cord-006460-3ayc0hne	212	10	of	of	IN
cord-006460-3ayc0hne	212	11	surgical	surgical	JJ
cord-006460-3ayc0hne	212	12	trauma	trauma	NN
cord-006460-3ayc0hne	212	13	and	and	CC
cord-006460-3ayc0hne	212	14	found	find	VBD
cord-006460-3ayc0hne	212	15	extensive	extensive	JJ
cord-006460-3ayc0hne	212	16	immunologic	immunologic	JJ
cord-006460-3ayc0hne	212	17	and	and	CC
cord-006460-3ayc0hne	212	18	inflammatory	inflammatory	JJ
cord-006460-3ayc0hne	212	19	responses	response	NNS
cord-006460-3ayc0hne	212	20	taking	take	VBG
cord-006460-3ayc0hne	212	21	place	place	NN
cord-006460-3ayc0hne	212	22	in	in	IN
cord-006460-3ayc0hne	212	23	the	the	DT
cord-006460-3ayc0hne	212	24	closed	closed	JJ
cord-006460-3ayc0hne	212	25	surgical	surgical	JJ
cord-006460-3ayc0hne	212	26	wound	wound	NN
cord-006460-3ayc0hne	212	27	that	that	WDT
cord-006460-3ayc0hne	212	28	would	would	MD
cord-006460-3ayc0hne	212	29	not	not	RB
cord-006460-3ayc0hne	212	30	be	be	VB
cord-006460-3ayc0hne	212	31	recognized	recognize	VBN
cord-006460-3ayc0hne	212	32	in	in	IN
cord-006460-3ayc0hne	212	33	blood	blood	NN
cord-006460-3ayc0hne	212	34	samples	sample	NNS
cord-006460-3ayc0hne	212	35	.	.	.
cord-006460-3ayc0hne	213	1	Other	other	JJ
cord-006460-3ayc0hne	213	2	complexities	complexity	NNS
cord-006460-3ayc0hne	213	3	include	include	VBP
cord-006460-3ayc0hne	213	4	pleiotropy	pleiotropy	NN
cord-006460-3ayc0hne	213	5	and	and	CC
cord-006460-3ayc0hne	213	6	redundancy	redundancy	NN
cord-006460-3ayc0hne	213	7	in	in	IN
cord-006460-3ayc0hne	213	8	cytokines	cytokine	NNS
cord-006460-3ayc0hne	213	9	,	,	,
cord-006460-3ayc0hne	213	10	genetic	genetic	JJ
cord-006460-3ayc0hne	213	11	variations	variation	NNS
cord-006460-3ayc0hne	213	12	in	in	IN
cord-006460-3ayc0hne	213	13	the	the	DT
cord-006460-3ayc0hne	213	14	response	response	NN
cord-006460-3ayc0hne	213	15	to	to	IN
cord-006460-3ayc0hne	213	16	lipopolysaccharide	lipopolysaccharide	NN
cord-006460-3ayc0hne	213	17	(	(	-LRB-
cord-006460-3ayc0hne	213	18	LPS	LPS	NNP
cord-006460-3ayc0hne	213	19	)	)	-RRB-
cord-006460-3ayc0hne	213	20	[	[	-LRB-
cord-006460-3ayc0hne	213	21	56	56	CD
cord-006460-3ayc0hne	213	22	]	]	-RRB-
cord-006460-3ayc0hne	213	23	,	,	,
cord-006460-3ayc0hne	213	24	polymorphic	polymorphic	JJ
cord-006460-3ayc0hne	213	25	HSPs	hsp	NNS
cord-006460-3ayc0hne	213	26	,	,	,
cord-006460-3ayc0hne	213	27	and	and	CC
cord-006460-3ayc0hne	213	28	differential	differential	JJ
cord-006460-3ayc0hne	213	29	receptor	receptor	NN
cord-006460-3ayc0hne	213	30	subtypes	subtype	NNS
cord-006460-3ayc0hne	213	31	as	as	IN
cord-006460-3ayc0hne	213	32	cited	cite	VBN
cord-006460-3ayc0hne	213	33	above	above	RB
cord-006460-3ayc0hne	213	34	.	.	.
cord-006460-3ayc0hne	214	1	Also	also	RB
cord-006460-3ayc0hne	214	2	present	present	JJ
cord-006460-3ayc0hne	214	3	are	be	VBP
cord-006460-3ayc0hne	214	4	discordant	discordant	JJ
cord-006460-3ayc0hne	214	5	super	super	JJ
cord-006460-3ayc0hne	214	6	family	family	NN
cord-006460-3ayc0hne	214	7	gene	gene	NN
cord-006460-3ayc0hne	214	8	expression	expression	NN
cord-006460-3ayc0hne	214	9	,	,	,
cord-006460-3ayc0hne	214	10	a	a	DT
cord-006460-3ayc0hne	214	11	gene	gene	NN
cord-006460-3ayc0hne	214	12	promoter	promoter	NN
cord-006460-3ayc0hne	214	13	polymorphism	polymorphism	NN
cord-006460-3ayc0hne	214	14	and	and	CC
cord-006460-3ayc0hne	214	15	receptor	receptor	NN
cord-006460-3ayc0hne	214	16	antagonist	antagonist	NN
cord-006460-3ayc0hne	214	17	polymorphism	polymorphism	NN
cord-006460-3ayc0hne	214	18	and	and	CC
cord-006460-3ayc0hne	214	19	,	,	,
cord-006460-3ayc0hne	214	20	of	of	IN
cord-006460-3ayc0hne	214	21	course	course	NN
cord-006460-3ayc0hne	214	22	,	,	,
cord-006460-3ayc0hne	214	23	cytokine	cytokine	NN
cord-006460-3ayc0hne	214	24	microsatellites	microsatellite	NNS
cord-006460-3ayc0hne	214	25	[	[	-LRB-
cord-006460-3ayc0hne	214	26	57	57	CD
cord-006460-3ayc0hne	214	27	]	]	-RRB-
cord-006460-3ayc0hne	214	28	.	.	.
cord-006460-3ayc0hne	215	1	An	an	DT
cord-006460-3ayc0hne	215	2	example	example	NN
cord-006460-3ayc0hne	215	3	was	be	VBD
cord-006460-3ayc0hne	215	4	described	describe	VBN
cord-006460-3ayc0hne	215	5	by	by	IN
cord-006460-3ayc0hne	215	6	Sh	Sh	NNP
cord-006460-3ayc0hne	215	7	et	et	NNP
cord-006460-3ayc0hne	215	8	al	al	NNP
cord-006460-3ayc0hne	215	9	.	.	.
cord-006460-3ayc0hne	216	1	[	[	-LRB-
cord-006460-3ayc0hne	216	2	7	7	CD
cord-006460-3ayc0hne	216	3	]	]	-RRB-
cord-006460-3ayc0hne	216	4	.	.	.
cord-006460-3ayc0hne	217	1	The	the	DT
cord-006460-3ayc0hne	217	2	association	association	NN
cord-006460-3ayc0hne	217	3	of	of	IN
cord-006460-3ayc0hne	217	4	TNF	TNF	NNP
cord-006460-3ayc0hne	217	5	microsatellites	microsatellite	NNS
cord-006460-3ayc0hne	217	6	with	with	IN
cord-006460-3ayc0hne	217	7	outcome	outcome	NN
cord-006460-3ayc0hne	217	8	in	in	IN
cord-006460-3ayc0hne	217	9	sepsis	sepsis	NN
cord-006460-3ayc0hne	217	10	indicated	indicate	VBD
cord-006460-3ayc0hne	217	11	that	that	IN
cord-006460-3ayc0hne	217	12	TNF-6	TNF-6	NNP
cord-006460-3ayc0hne	217	13	and	and	CC
cord-006460-3ayc0hne	217	14	TNF-1	TNF-1	NNP
cord-006460-3ayc0hne	217	15	levels	level	NNS
cord-006460-3ayc0hne	217	16	increase	increase	VBP
cord-006460-3ayc0hne	217	17	in	in	IN
cord-006460-3ayc0hne	217	18	septic	septic	JJ
cord-006460-3ayc0hne	217	19	patients	patient	NNS
cord-006460-3ayc0hne	217	20	;	;	:
cord-006460-3ayc0hne	217	21	however	however	RB
cord-006460-3ayc0hne	217	22	,	,	,
cord-006460-3ayc0hne	217	23	TNF-10	TNF-10	NNP
cord-006460-3ayc0hne	217	24	increased	increase	VBD
cord-006460-3ayc0hne	217	25	in	in	IN
cord-006460-3ayc0hne	217	26	non	non	NNS
cord-006460-3ayc0hne	217	27	-	-	NNS
cord-006460-3ayc0hne	217	28	survivors	survivor	NNS
cord-006460-3ayc0hne	217	29	[	[	-LRB-
cord-006460-3ayc0hne	217	30	44	44	CD
cord-006460-3ayc0hne	217	31	,	,	,
cord-006460-3ayc0hne	217	32	45	45	CD
cord-006460-3ayc0hne	217	33	]	]	-RRB-
cord-006460-3ayc0hne	217	34	.	.	.
cord-006460-3ayc0hne	218	1	There	there	EX
cord-006460-3ayc0hne	218	2	is	be	VBZ
cord-006460-3ayc0hne	218	3	a	a	DT
cord-006460-3ayc0hne	218	4	tremendous	tremendous	JJ
cord-006460-3ayc0hne	218	5	disparity	disparity	NN
cord-006460-3ayc0hne	218	6	between	between	IN
cord-006460-3ayc0hne	218	7	scientific	scientific	JJ
cord-006460-3ayc0hne	218	8	knowledge	knowledge	NN
cord-006460-3ayc0hne	218	9	about	about	IN
cord-006460-3ayc0hne	218	10	endotoxin	endotoxin	NN
cord-006460-3ayc0hne	218	11	and	and	CC
cord-006460-3ayc0hne	218	12	the	the	DT
cord-006460-3ayc0hne	218	13	clinical	clinical	JJ
cord-006460-3ayc0hne	218	14	usefulness	usefulness	NN
cord-006460-3ayc0hne	218	15	of	of	IN
cord-006460-3ayc0hne	218	16	that	that	DT
cord-006460-3ayc0hne	218	17	knowledge	knowledge	NN
cord-006460-3ayc0hne	218	18	.	.	.
cord-006460-3ayc0hne	219	1	There	there	EX
cord-006460-3ayc0hne	219	2	is	be	VBZ
cord-006460-3ayc0hne	219	3	nothing	nothing	NN
cord-006460-3ayc0hne	219	4	at	at	IN
cord-006460-3ayc0hne	219	5	the	the	DT
cord-006460-3ayc0hne	219	6	present	present	JJ
cord-006460-3ayc0hne	219	7	time	time	NN
cord-006460-3ayc0hne	219	8	that	that	WDT
cord-006460-3ayc0hne	219	9	seems	seem	VBZ
cord-006460-3ayc0hne	219	10	clinically	clinically	RB
cord-006460-3ayc0hne	219	11	useful	useful	JJ
cord-006460-3ayc0hne	219	12	about	about	IN
cord-006460-3ayc0hne	219	13	the	the	DT
cord-006460-3ayc0hne	219	14	knowledge	knowledge	NN
cord-006460-3ayc0hne	219	15	on	on	IN
cord-006460-3ayc0hne	219	16	endotoxin	endotoxin	NN
cord-006460-3ayc0hne	219	17	.	.	.
cord-006460-3ayc0hne	220	1	We	-PRON-	PRP
cord-006460-3ayc0hne	220	2	know	know	VBP
cord-006460-3ayc0hne	220	3	that	that	IN
cord-006460-3ayc0hne	220	4	it	-PRON-	PRP
cord-006460-3ayc0hne	220	5	is	be	VBZ
cord-006460-3ayc0hne	220	6	present	present	JJ
cord-006460-3ayc0hne	220	7	in	in	IN
cord-006460-3ayc0hne	220	8	the	the	DT
cord-006460-3ayc0hne	220	9	walls	wall	NNS
cord-006460-3ayc0hne	220	10	of	of	IN
cord-006460-3ayc0hne	220	11	gramnegative	gramnegative	JJ
cord-006460-3ayc0hne	220	12	organisms	organism	NNS
cord-006460-3ayc0hne	220	13	.	.	.
cord-006460-3ayc0hne	221	1	We	-PRON-	PRP
cord-006460-3ayc0hne	221	2	know	know	VBP
cord-006460-3ayc0hne	221	3	that	that	IN
cord-006460-3ayc0hne	221	4	it	-PRON-	PRP
cord-006460-3ayc0hne	221	5	does	do	VBZ
cord-006460-3ayc0hne	221	6	all	all	DT
cord-006460-3ayc0hne	221	7	sorts	sort	NNS
cord-006460-3ayc0hne	221	8	of	of	IN
cord-006460-3ayc0hne	221	9	bad	bad	JJ
cord-006460-3ayc0hne	221	10	things	thing	NNS
cord-006460-3ayc0hne	221	11	when	when	WRB
cord-006460-3ayc0hne	221	12	it	-PRON-	PRP
cord-006460-3ayc0hne	221	13	is	be	VBZ
cord-006460-3ayc0hne	221	14	injected	inject	VBN
cord-006460-3ayc0hne	221	15	into	into	IN
cord-006460-3ayc0hne	221	16	animals	animal	NNS
cord-006460-3ayc0hne	221	17	and	and	CC
cord-006460-3ayc0hne	221	18	people	people	NNS
cord-006460-3ayc0hne	221	19	,	,	,
cord-006460-3ayc0hne	221	20	but	but	CC
cord-006460-3ayc0hne	221	21	we	-PRON-	PRP
cord-006460-3ayc0hne	221	22	still	still	RB
cord-006460-3ayc0hne	221	23	have	have	VBP
cord-006460-3ayc0hne	221	24	no	no	DT
cord-006460-3ayc0hne	221	25	information	information	NN
cord-006460-3ayc0hne	221	26	about	about	IN
cord-006460-3ayc0hne	221	27	what	what	WP
cord-006460-3ayc0hne	221	28	it	-PRON-	PRP
cord-006460-3ayc0hne	221	29	does	do	VBZ
cord-006460-3ayc0hne	221	30	in	in	IN
cord-006460-3ayc0hne	221	31	various	various	JJ
cord-006460-3ayc0hne	221	32	sick	sick	JJ
cord-006460-3ayc0hne	221	33	patients	patient	NNS
cord-006460-3ayc0hne	221	34	and	and	CC
cord-006460-3ayc0hne	221	35	what	what	WP
cord-006460-3ayc0hne	221	36	we	-PRON-	PRP
cord-006460-3ayc0hne	221	37	might	may	MD
cord-006460-3ayc0hne	221	38	do	do	VB
cord-006460-3ayc0hne	221	39	about	about	IN
cord-006460-3ayc0hne	221	40	it	-PRON-	PRP
cord-006460-3ayc0hne	221	41	.	.	.
cord-006460-3ayc0hne	222	1	New	new	JJ
cord-006460-3ayc0hne	222	2	developments	development	NNS
cord-006460-3ayc0hne	222	3	may	may	MD
cord-006460-3ayc0hne	222	4	help	help	VB
cord-006460-3ayc0hne	222	5	[	[	-LRB-
cord-006460-3ayc0hne	222	6	58	58	CD
cord-006460-3ayc0hne	222	7	]	]	-RRB-
cord-006460-3ayc0hne	222	8	.	.	.
cord-006460-3ayc0hne	223	1	O'Reilly	O'Reilly	NNP
cord-006460-3ayc0hne	223	2	et	et	NNP
cord-006460-3ayc0hne	223	3	al	al	NNP
cord-006460-3ayc0hne	223	4	.	.	.
cord-006460-3ayc0hne	224	1	[	[	-LRB-
cord-006460-3ayc0hne	224	2	59	59	CD
cord-006460-3ayc0hne	224	3	]	]	-RRB-
cord-006460-3ayc0hne	224	4	reported	report	VBN
cord-006460-3ayc0hne	224	5	on	on	IN
cord-006460-3ayc0hne	224	6	endotoxin	endotoxin	NN
cord-006460-3ayc0hne	224	7	sepsis	sepsis	NN
cord-006460-3ayc0hne	224	8	and	and	CC
cord-006460-3ayc0hne	224	9	the	the	DT
cord-006460-3ayc0hne	224	10	primrose	primrose	NN
cord-006460-3ayc0hne	224	11	path	path	NN
cord-006460-3ayc0hne	224	12	.	.	.
cord-006460-3ayc0hne	225	1	They	-PRON-	PRP
cord-006460-3ayc0hne	225	2	reviewed	review	VBD
cord-006460-3ayc0hne	225	3	how	how	WRB
cord-006460-3ayc0hne	225	4	the	the	DT
cord-006460-3ayc0hne	225	5	use	use	NN
cord-006460-3ayc0hne	225	6	of	of	IN
cord-006460-3ayc0hne	225	7	endo	endo	NN
cord-006460-3ayc0hne	225	8	-	-	HYPH
cord-006460-3ayc0hne	225	9	toxin	toxin	NN
cord-006460-3ayc0hne	225	10	models	model	NNS
cord-006460-3ayc0hne	225	11	has	have	VBZ
cord-006460-3ayc0hne	225	12	failed	fail	VBN
cord-006460-3ayc0hne	225	13	to	to	TO
cord-006460-3ayc0hne	225	14	identify	identify	VB
cord-006460-3ayc0hne	225	15	a	a	DT
cord-006460-3ayc0hne	225	16	clinically	clinically	RB
cord-006460-3ayc0hne	225	17	useful	useful	JJ
cord-006460-3ayc0hne	225	18	therapeutic	therapeutic	JJ
cord-006460-3ayc0hne	225	19	agent	agent	NN
cord-006460-3ayc0hne	225	20	for	for	IN
cord-006460-3ayc0hne	225	21	the	the	DT
cord-006460-3ayc0hne	225	22	treatment	treatment	NN
cord-006460-3ayc0hne	225	23	of	of	IN
cord-006460-3ayc0hne	225	24	sepsis	sepsis	NN
cord-006460-3ayc0hne	225	25	.	.	.
cord-006460-3ayc0hne	226	1	Archibald	Archibald	NNP
cord-006460-3ayc0hne	226	2	Philip	Philip	NNP
cord-006460-3ayc0hne	226	3	Primrose	Primrose	NNP
cord-006460-3ayc0hne	226	4	was	be	VBD
cord-006460-3ayc0hne	226	5	the	the	DT
cord-006460-3ayc0hne	226	6	Fifth	Fifth	NNP
cord-006460-3ayc0hne	226	7	Earl	Earl	NNP
cord-006460-3ayc0hne	226	8	of	of	IN
cord-006460-3ayc0hne	226	9	Roseberg	Roseberg	NNP
cord-006460-3ayc0hne	226	10	.	.	.
cord-006460-3ayc0hne	227	1	He	-PRON-	PRP
cord-006460-3ayc0hne	227	2	promoted	promote	VBD
cord-006460-3ayc0hne	227	3	the	the	DT
cord-006460-3ayc0hne	227	4	concept	concept	NN
cord-006460-3ayc0hne	227	5	that	that	IN
cord-006460-3ayc0hne	227	6	the	the	DT
cord-006460-3ayc0hne	227	7	aristocracy	aristocracy	NN
cord-006460-3ayc0hne	227	8	and	and	CC
cord-006460-3ayc0hne	227	9	monarchy	monarchy	NN
cord-006460-3ayc0hne	227	10	are	be	VBP
cord-006460-3ayc0hne	227	11	no	no	RB
cord-006460-3ayc0hne	227	12	longer	long	RBR
cord-006460-3ayc0hne	227	13	necessary	necessary	JJ
cord-006460-3ayc0hne	227	14	.	.	.
cord-006460-3ayc0hne	228	1	This	this	DT
cord-006460-3ayc0hne	228	2	was	be	VBD
cord-006460-3ayc0hne	228	3	labeled	label	VBN
cord-006460-3ayc0hne	228	4	the	the	DT
cord-006460-3ayc0hne	228	5	"	"	``
cord-006460-3ayc0hne	228	6	primrose	primrose	NN
cord-006460-3ayc0hne	228	7	path	path	NN
cord-006460-3ayc0hne	228	8	,	,	,
cord-006460-3ayc0hne	228	9	a	a	DT
cord-006460-3ayc0hne	228	10	tempting	tempting	JJ
cord-006460-3ayc0hne	228	11	but	but	CC
cord-006460-3ayc0hne	228	12	hazardous	hazardous	JJ
cord-006460-3ayc0hne	228	13	course	course	NN
cord-006460-3ayc0hne	228	14	.	.	.
cord-006460-3ayc0hne	228	15	"	"	''
cord-006460-3ayc0hne	229	1	Endotoxin	endotoxin	NN
cord-006460-3ayc0hne	229	2	models	model	NNS
cord-006460-3ayc0hne	229	3	of	of	IN
cord-006460-3ayc0hne	229	4	sepsis	sepsis	NN
cord-006460-3ayc0hne	229	5	may	may	MD
cord-006460-3ayc0hne	229	6	be	be	VB
cord-006460-3ayc0hne	229	7	the	the	DT
cord-006460-3ayc0hne	229	8	primrose	primrose	NN
cord-006460-3ayc0hne	229	9	path	path	NN
cord-006460-3ayc0hne	229	10	of	of	IN
cord-006460-3ayc0hne	229	11	research	research	NN
cord-006460-3ayc0hne	229	12	.	.	.
cord-006460-3ayc0hne	230	1	There	there	EX
cord-006460-3ayc0hne	230	2	are	be	VBP
cord-006460-3ayc0hne	230	3	a	a	DT
cord-006460-3ayc0hne	230	4	number	number	NN
cord-006460-3ayc0hne	230	5	of	of	IN
cord-006460-3ayc0hne	230	6	new	new	JJ
cord-006460-3ayc0hne	230	7	and	and	CC
cord-006460-3ayc0hne	230	8	confusing	confusing	JJ
cord-006460-3ayc0hne	230	9	concepts	concept	NNS
cord-006460-3ayc0hne	230	10	relating	relate	VBG
cord-006460-3ayc0hne	230	11	to	to	IN
cord-006460-3ayc0hne	230	12	organ	organ	NN
cord-006460-3ayc0hne	230	13	damage	damage	NN
cord-006460-3ayc0hne	230	14	that	that	WDT
cord-006460-3ayc0hne	230	15	have	have	VBP
cord-006460-3ayc0hne	230	16	been	be	VBN
cord-006460-3ayc0hne	230	17	heretofore	heretofore	RB
cord-006460-3ayc0hne	230	18	unknown	unknown	JJ
cord-006460-3ayc0hne	230	19	.	.	.
cord-006460-3ayc0hne	231	1	One	one	CD
cord-006460-3ayc0hne	231	2	of	of	IN
cord-006460-3ayc0hne	231	3	these	these	DT
cord-006460-3ayc0hne	231	4	is	be	VBZ
cord-006460-3ayc0hne	231	5	that	that	IN
cord-006460-3ayc0hne	231	6	arteriosclerosis	arteriosclerosis	NN
cord-006460-3ayc0hne	231	7	may	may	MD
cord-006460-3ayc0hne	231	8	be	be	VB
cord-006460-3ayc0hne	231	9	the	the	DT
cord-006460-3ayc0hne	231	10	result	result	NN
cord-006460-3ayc0hne	231	11	of	of	IN
cord-006460-3ayc0hne	231	12	infection	infection	NN
cord-006460-3ayc0hne	231	13	,	,	,
cord-006460-3ayc0hne	231	14	a	a	DT
cord-006460-3ayc0hne	231	15	possibility	possibility	NN
cord-006460-3ayc0hne	231	16	suggested	suggest	VBN
cord-006460-3ayc0hne	231	17	by	by	IN
cord-006460-3ayc0hne	231	18	the	the	DT
cord-006460-3ayc0hne	231	19	finding	finding	NN
cord-006460-3ayc0hne	231	20	of	of	IN
cord-006460-3ayc0hne	231	21	organisms	organism	NNS
cord-006460-3ayc0hne	231	22	in	in	IN
cord-006460-3ayc0hne	231	23	arteriosclerotic	arteriosclerotic	JJ
cord-006460-3ayc0hne	231	24	plaques	plaque	NNS
cord-006460-3ayc0hne	231	25	.	.	.
cord-006460-3ayc0hne	232	1	Hatch	Hatch	NNP
cord-006460-3ayc0hne	232	2	[	[	-LRB-
cord-006460-3ayc0hne	232	3	60	60	CD
cord-006460-3ayc0hne	232	4	]	]	-RRB-
cord-006460-3ayc0hne	232	5	reported	report	VBD
cord-006460-3ayc0hne	232	6	finding	find	VBG
cord-006460-3ayc0hne	232	7	the	the	DT
cord-006460-3ayc0hne	232	8	organism	organism	NN
cord-006460-3ayc0hne	232	9	Chlamydia	Chlamydia	NNP
cord-006460-3ayc0hne	232	10	pneumoniae	pneumoniae	NN
cord-006460-3ayc0hne	232	11	in	in	IN
cord-006460-3ayc0hne	232	12	70	70	CD
cord-006460-3ayc0hne	232	13	%	%	NN
cord-006460-3ayc0hne	232	14	of	of	IN
cord-006460-3ayc0hne	232	15	arteriosclerotic	arteriosclerotic	JJ
cord-006460-3ayc0hne	232	16	plaques	plaque	NNS
cord-006460-3ayc0hne	232	17	.	.	.
cord-006460-3ayc0hne	233	1	Herpes	Herpes	NNP
cord-006460-3ayc0hne	233	2	simplex	simplex	NN
cord-006460-3ayc0hne	233	3	virus	virus	NN
cord-006460-3ayc0hne	233	4	(	(	-LRB-
cord-006460-3ayc0hne	233	5	HSV	HSV	NNP
cord-006460-3ayc0hne	233	6	)	)	-RRB-
cord-006460-3ayc0hne	233	7	has	have	VBZ
cord-006460-3ayc0hne	233	8	been	be	VBN
cord-006460-3ayc0hne	233	9	implicated	implicate	VBN
cord-006460-3ayc0hne	233	10	,	,	,
cord-006460-3ayc0hne	233	11	as	as	IN
cord-006460-3ayc0hne	233	12	has	have	VBZ
cord-006460-3ayc0hne	233	13	cytomegalovirus	cytomegalovirus	NN
cord-006460-3ayc0hne	233	14	(	(	-LRB-
cord-006460-3ayc0hne	233	15	CMV	CMV	NNP
cord-006460-3ayc0hne	233	16	)	)	-RRB-
cord-006460-3ayc0hne	233	17	[	[	-LRB-
cord-006460-3ayc0hne	233	18	61	61	CD
cord-006460-3ayc0hne	233	19	,	,	,
cord-006460-3ayc0hne	233	20	62	62	CD
cord-006460-3ayc0hne	233	21	]	]	-RRB-
cord-006460-3ayc0hne	233	22	.	.	.
cord-006460-3ayc0hne	234	1	Others	other	NNS
cord-006460-3ayc0hne	234	2	have	have	VBP
cord-006460-3ayc0hne	234	3	suggested	suggest	VBN
cord-006460-3ayc0hne	234	4	that	that	IN
cord-006460-3ayc0hne	234	5	Helicobacter	Helicobacter	NNP
cord-006460-3ayc0hne	234	6	pylori	pylori	NN
cord-006460-3ayc0hne	234	7	may	may	MD
cord-006460-3ayc0hne	234	8	be	be	VB
cord-006460-3ayc0hne	234	9	involved	involve	VBN
cord-006460-3ayc0hne	234	10	[	[	-LRB-
cord-006460-3ayc0hne	234	11	63	63	CD
cord-006460-3ayc0hne	234	12	]	]	-RRB-
cord-006460-3ayc0hne	234	13	.	.	.
cord-006460-3ayc0hne	235	1	Dental	dental	JJ
cord-006460-3ayc0hne	235	2	infection	infection	NN
cord-006460-3ayc0hne	235	3	and	and	CC
cord-006460-3ayc0hne	235	4	remote	remote	JJ
cord-006460-3ayc0hne	235	5	infection	infection	NN
cord-006460-3ayc0hne	235	6	elsewhere	elsewhere	RB
cord-006460-3ayc0hne	235	7	in	in	IN
cord-006460-3ayc0hne	235	8	the	the	DT
cord-006460-3ayc0hne	235	9	extremities	extremity	NNS
cord-006460-3ayc0hne	235	10	have	have	VBP
cord-006460-3ayc0hne	235	11	been	be	VBN
cord-006460-3ayc0hne	235	12	implicated	implicate	VBN
cord-006460-3ayc0hne	235	13	in	in	IN
cord-006460-3ayc0hne	235	14	rapid	rapid	JJ
cord-006460-3ayc0hne	235	15	occlusion	occlusion	NN
cord-006460-3ayc0hne	235	16	of	of	IN
cord-006460-3ayc0hne	235	17	coronary	coronary	JJ
cord-006460-3ayc0hne	235	18	arteries	artery	NNS
cord-006460-3ayc0hne	235	19	[	[	-LRB-
cord-006460-3ayc0hne	235	20	64	64	CD
cord-006460-3ayc0hne	235	21	]	]	-RRB-
cord-006460-3ayc0hne	235	22	.	.	.
cord-006460-3ayc0hne	236	1	Are	be	VBP
cord-006460-3ayc0hne	236	2	these	these	DT
cord-006460-3ayc0hne	236	3	the	the	DT
cord-006460-3ayc0hne	236	4	causes	cause	NNS
cord-006460-3ayc0hne	236	5	or	or	CC
cord-006460-3ayc0hne	236	6	are	be	VBP
cord-006460-3ayc0hne	236	7	they	-PRON-	PRP
cord-006460-3ayc0hne	236	8	associations	association	NNS
cord-006460-3ayc0hne	236	9	that	that	WDT
cord-006460-3ayc0hne	236	10	are	be	VBP
cord-006460-3ayc0hne	236	11	not	not	RB
cord-006460-3ayc0hne	236	12	totally	totally	RB
cord-006460-3ayc0hne	236	13	worked	work	VBN
cord-006460-3ayc0hne	236	14	out	out	RP
cord-006460-3ayc0hne	236	15	?	?	.
cord-006460-3ayc0hne	237	1	The	the	DT
cord-006460-3ayc0hne	237	2	circumstantial	circumstantial	JJ
cord-006460-3ayc0hne	237	3	evidence	evidence	NN
cord-006460-3ayc0hne	237	4	is	be	VBZ
cord-006460-3ayc0hne	237	5	very	very	RB
cord-006460-3ayc0hne	237	6	interesting	interesting	JJ
cord-006460-3ayc0hne	237	7	.	.	.
cord-006460-3ayc0hne	238	1	There	there	EX
cord-006460-3ayc0hne	238	2	are	be	VBP
cord-006460-3ayc0hne	238	3	also	also	RB
cord-006460-3ayc0hne	238	4	tremendous	tremendous	JJ
cord-006460-3ayc0hne	238	5	genetic	genetic	JJ
cord-006460-3ayc0hne	238	6	differences	difference	NNS
cord-006460-3ayc0hne	238	7	in	in	IN
cord-006460-3ayc0hne	238	8	disease	disease	NN
cord-006460-3ayc0hne	238	9	susceptibility	susceptibility	NN
cord-006460-3ayc0hne	238	10	and	and	CC
cord-006460-3ayc0hne	238	11	these	these	DT
cord-006460-3ayc0hne	238	12	are	be	VBP
cord-006460-3ayc0hne	238	13	now	now	RB
cord-006460-3ayc0hne	238	14	being	be	VBG
cord-006460-3ayc0hne	238	15	studied	study	VBN
cord-006460-3ayc0hne	238	16	vigorously	vigorously	RB
cord-006460-3ayc0hne	238	17	.	.	.
cord-006460-3ayc0hne	239	1	Chaudry	Chaudry	NNP
cord-006460-3ayc0hne	239	2	et	et	IN
cord-006460-3ayc0hne	239	3	al	al	NNP
cord-006460-3ayc0hne	239	4	.	.	.
cord-006460-3ayc0hne	240	1	[	[	-LRB-
cord-006460-3ayc0hne	240	2	48	48	CD
cord-006460-3ayc0hne	240	3	]	]	-RRB-
cord-006460-3ayc0hne	240	4	found	find	VBN
cord-006460-3ayc0hne	240	5	in	in	IN
cord-006460-3ayc0hne	240	6	animals	animal	NNS
cord-006460-3ayc0hne	240	7	with	with	IN
cord-006460-3ayc0hne	240	8	trauma	trauma	NN
cord-006460-3ayc0hne	240	9	that	that	IN
cord-006460-3ayc0hne	240	10	infection	infection	NN
cord-006460-3ayc0hne	240	11	was	be	VBD
cord-006460-3ayc0hne	240	12	more	more	RBR
cord-006460-3ayc0hne	240	13	prevalent	prevalent	JJ
cord-006460-3ayc0hne	240	14	in	in	IN
cord-006460-3ayc0hne	240	15	males	male	NNS
cord-006460-3ayc0hne	240	16	and	and	CC
cord-006460-3ayc0hne	240	17	that	that	IN
cord-006460-3ayc0hne	240	18	this	this	DT
cord-006460-3ayc0hne	240	19	was	be	VBD
cord-006460-3ayc0hne	240	20	related	relate	VBN
cord-006460-3ayc0hne	240	21	to	to	IN
cord-006460-3ayc0hne	240	22	testosterone	testosterone	NN
cord-006460-3ayc0hne	240	23	.	.	.
cord-006460-3ayc0hne	241	1	They	-PRON-	PRP
cord-006460-3ayc0hne	241	2	performed	perform	VBD
cord-006460-3ayc0hne	241	3	a	a	DT
cord-006460-3ayc0hne	241	4	number	number	NN
cord-006460-3ayc0hne	241	5	of	of	IN
cord-006460-3ayc0hne	241	6	studies	study	NNS
cord-006460-3ayc0hne	241	7	supporting	support	VBG
cord-006460-3ayc0hne	241	8	this	this	DT
cord-006460-3ayc0hne	241	9	relationship	relationship	NN
cord-006460-3ayc0hne	241	10	[	[	-LRB-
cord-006460-3ayc0hne	241	11	65	65	CD
cord-006460-3ayc0hne	241	12	]	]	-RRB-
cord-006460-3ayc0hne	241	13	.	.	.
cord-006460-3ayc0hne	242	1	The	the	DT
cord-006460-3ayc0hne	242	2	male	male	JJ
cord-006460-3ayc0hne	242	3	swagger	swagger	NN
cord-006460-3ayc0hne	242	4	and	and	CC
cord-006460-3ayc0hne	242	5	ornamentation	ornamentation	NN
cord-006460-3ayc0hne	242	6	in	in	IN
cord-006460-3ayc0hne	242	7	animals	animal	NNS
cord-006460-3ayc0hne	242	8	suggests	suggest	VBZ
cord-006460-3ayc0hne	242	9	a	a	DT
cord-006460-3ayc0hne	242	10	decreased	decrease	VBN
cord-006460-3ayc0hne	242	11	humoral	humoral	JJ
cord-006460-3ayc0hne	242	12	immune	immune	JJ
cord-006460-3ayc0hne	242	13	response	response	NN
cord-006460-3ayc0hne	242	14	as	as	IN
cord-006460-3ayc0hne	242	15	the	the	DT
cord-006460-3ayc0hne	242	16	basis	basis	NN
cord-006460-3ayc0hne	242	17	for	for	IN
cord-006460-3ayc0hne	242	18	this	this	DT
cord-006460-3ayc0hne	242	19	[	[	-LRB-
cord-006460-3ayc0hne	242	20	66	66	CD
cord-006460-3ayc0hne	242	21	]	]	-RRB-
cord-006460-3ayc0hne	242	22	.	.	.
cord-006460-3ayc0hne	243	1	Eachempati	Eachempati	NNP
cord-006460-3ayc0hne	243	2	et	et	NNP
cord-006460-3ayc0hne	243	3	al	al	NNP
cord-006460-3ayc0hne	243	4	.	.	.
cord-006460-3ayc0hne	244	1	[	[	-LRB-
cord-006460-3ayc0hne	244	2	67	67	CD
cord-006460-3ayc0hne	244	3	]	]	-RRB-
cord-006460-3ayc0hne	244	4	,	,	,
cord-006460-3ayc0hne	244	5	however	however	RB
cord-006460-3ayc0hne	244	6	,	,	,
cord-006460-3ayc0hne	244	7	described	describe	VBN
cord-006460-3ayc0hne	244	8	increased	increase	VBN
cord-006460-3ayc0hne	244	9	mortality	mortality	NN
cord-006460-3ayc0hne	244	10	from	from	IN
cord-006460-3ayc0hne	244	11	sepsis	sepsis	NN
cord-006460-3ayc0hne	244	12	in	in	IN
cord-006460-3ayc0hne	244	13	female	female	JJ
cord-006460-3ayc0hne	244	14	patients	patient	NNS
cord-006460-3ayc0hne	244	15	,	,	,
cord-006460-3ayc0hne	244	16	as	as	IN
cord-006460-3ayc0hne	244	17	did	do	VBD
cord-006460-3ayc0hne	244	18	Crabtree	Crabtree	NNP
cord-006460-3ayc0hne	244	19	et	et	NNP
cord-006460-3ayc0hne	244	20	al	al	NNP
cord-006460-3ayc0hne	244	21	.	.	.
cord-006460-3ayc0hne	245	1	[	[	-LRB-
cord-006460-3ayc0hne	245	2	68	68	CD
cord-006460-3ayc0hne	245	3	]	]	-RRB-
cord-006460-3ayc0hne	245	4	.	.	.
cord-006460-3ayc0hne	246	1	However	however	RB
cord-006460-3ayc0hne	246	2	,	,	,
cord-006460-3ayc0hne	246	3	Offner	Offner	NNP
cord-006460-3ayc0hne	246	4	et	et	NNP
cord-006460-3ayc0hne	246	5	al	al	NNP
cord-006460-3ayc0hne	246	6	.	.	.
cord-006460-3ayc0hne	247	1	[	[	-LRB-
cord-006460-3ayc0hne	247	2	69	69	CD
cord-006460-3ayc0hne	247	3	]	]	-RRB-
cord-006460-3ayc0hne	247	4	found	find	VBN
cord-006460-3ayc0hne	247	5	increased	increase	VBN
cord-006460-3ayc0hne	247	6	infections	infection	NNS
cord-006460-3ayc0hne	247	7	in	in	IN
cord-006460-3ayc0hne	247	8	males	male	NNS
cord-006460-3ayc0hne	247	9	after	after	IN
cord-006460-3ayc0hne	247	10	trauma	trauma	NN
cord-006460-3ayc0hne	247	11	.	.	.
cord-006460-3ayc0hne	248	1	In	in	IN
cord-006460-3ayc0hne	248	2	autoimmune	autoimmune	JJ
cord-006460-3ayc0hne	248	3	diseases	disease	NNS
cord-006460-3ayc0hne	248	4	,	,	,
cord-006460-3ayc0hne	248	5	estrogen	estrogen	NN
cord-006460-3ayc0hne	248	6	and	and	CC
cord-006460-3ayc0hne	248	7	prolactin	prolactin	NN
cord-006460-3ayc0hne	248	8	seem	seem	VBP
cord-006460-3ayc0hne	248	9	to	to	TO
cord-006460-3ayc0hne	248	10	be	be	VB
cord-006460-3ayc0hne	248	11	the	the	DT
cord-006460-3ayc0hne	248	12	problem	problem	NN
cord-006460-3ayc0hne	248	13	[	[	-LRB-
cord-006460-3ayc0hne	248	14	70	70	CD
cord-006460-3ayc0hne	248	15	]	]	-RRB-
cord-006460-3ayc0hne	248	16	.	.	.
cord-006460-3ayc0hne	249	1	In	in	IN
cord-006460-3ayc0hne	249	2	comparison	comparison	NN
cord-006460-3ayc0hne	249	3	with	with	IN
cord-006460-3ayc0hne	249	4	males	male	NNS
cord-006460-3ayc0hne	249	5	,	,	,
cord-006460-3ayc0hne	249	6	multiple	multiple	JJ
cord-006460-3ayc0hne	249	7	sclerosis	sclerosis	NN
cord-006460-3ayc0hne	249	8	occurs	occur	VBZ
cord-006460-3ayc0hne	249	9	two	two	CD
cord-006460-3ayc0hne	249	10	times	time	NNS
cord-006460-3ayc0hne	249	11	more	more	RBR
cord-006460-3ayc0hne	249	12	commonly	commonly	RB
cord-006460-3ayc0hne	249	13	in	in	IN
cord-006460-3ayc0hne	249	14	females	female	NNS
cord-006460-3ayc0hne	249	15	,	,	,
cord-006460-3ayc0hne	249	16	rheumatoid	rheumatoid	JJ
cord-006460-3ayc0hne	249	17	arthritis	arthritis	NN
cord-006460-3ayc0hne	249	18	occurs	occur	VBZ
cord-006460-3ayc0hne	249	19	three	three	CD
cord-006460-3ayc0hne	249	20	times	time	NNS
cord-006460-3ayc0hne	249	21	more	more	RBR
cord-006460-3ayc0hne	249	22	frequently	frequently	RB
cord-006460-3ayc0hne	249	23	,	,	,
cord-006460-3ayc0hne	249	24	and	and	CC
cord-006460-3ayc0hne	249	25	lupus	lupus	NN
cord-006460-3ayc0hne	249	26	erythematosus	erythematosus	NN
cord-006460-3ayc0hne	249	27	occurs	occur	VBZ
cord-006460-3ayc0hne	249	28	nine	nine	CD
cord-006460-3ayc0hne	249	29	times	time	NNS
cord-006460-3ayc0hne	249	30	more	more	RBR
cord-006460-3ayc0hne	249	31	often	often	RB
cord-006460-3ayc0hne	249	32	.	.	.
cord-006460-3ayc0hne	250	1	What	what	WP
cord-006460-3ayc0hne	250	2	is	be	VBZ
cord-006460-3ayc0hne	250	3	the	the	DT
cord-006460-3ayc0hne	250	4	answer	answer	NN
cord-006460-3ayc0hne	250	5	to	to	IN
cord-006460-3ayc0hne	250	6	this	this	DT
cord-006460-3ayc0hne	250	7	gender	gender	NN
cord-006460-3ayc0hne	250	8	gap	gap	NN
cord-006460-3ayc0hne	250	9	?	?	.
cord-006460-3ayc0hne	251	1	It	-PRON-	PRP
cord-006460-3ayc0hne	251	2	seems	seem	VBZ
cord-006460-3ayc0hne	251	3	that	that	IN
cord-006460-3ayc0hne	251	4	if	if	IN
cord-006460-3ayc0hne	251	5	you	-PRON-	PRP
cord-006460-3ayc0hne	251	6	are	be	VBP
cord-006460-3ayc0hne	251	7	injured	injure	VBN
cord-006460-3ayc0hne	251	8	,	,	,
cord-006460-3ayc0hne	251	9	you	-PRON-	PRP
cord-006460-3ayc0hne	251	10	are	be	VBP
cord-006460-3ayc0hne	251	11	better	well	JJR
cord-006460-3ayc0hne	251	12	off	off	RP
cord-006460-3ayc0hne	251	13	being	be	VBG
cord-006460-3ayc0hne	251	14	female	female	JJ
cord-006460-3ayc0hne	251	15	;	;	:
cord-006460-3ayc0hne	251	16	however	however	RB
cord-006460-3ayc0hne	251	17	,	,	,
cord-006460-3ayc0hne	251	18	if	if	IN
cord-006460-3ayc0hne	251	19	you	-PRON-	PRP
cord-006460-3ayc0hne	251	20	develop	develop	VBP
cord-006460-3ayc0hne	251	21	an	an	DT
cord-006460-3ayc0hne	251	22	infection	infection	NN
cord-006460-3ayc0hne	251	23	,	,	,
cord-006460-3ayc0hne	251	24	then	then	RB
cord-006460-3ayc0hne	251	25	you	-PRON-	PRP
cord-006460-3ayc0hne	251	26	are	be	VBP
cord-006460-3ayc0hne	251	27	better	well	JJR
cord-006460-3ayc0hne	251	28	off	off	RP
cord-006460-3ayc0hne	251	29	being	be	VBG
cord-006460-3ayc0hne	251	30	male	male	NN
cord-006460-3ayc0hne	251	31	.	.	.
cord-006460-3ayc0hne	252	1	What	what	WP
cord-006460-3ayc0hne	252	2	should	should	MD
cord-006460-3ayc0hne	252	3	you	-PRON-	PRP
cord-006460-3ayc0hne	252	4	do	do	VB
cord-006460-3ayc0hne	252	5	if	if	IN
cord-006460-3ayc0hne	252	6	you	-PRON-	PRP
cord-006460-3ayc0hne	252	7	are	be	VBP
cord-006460-3ayc0hne	252	8	injured	injure	VBN
cord-006460-3ayc0hne	252	9	and	and	CC
cord-006460-3ayc0hne	252	10	develop	develop	VB
cord-006460-3ayc0hne	252	11	an	an	DT
cord-006460-3ayc0hne	252	12	infection	infection	NN
cord-006460-3ayc0hne	252	13	?	?	.
cord-006460-3ayc0hne	253	1	Another	another	DT
cord-006460-3ayc0hne	253	2	new	new	JJ
cord-006460-3ayc0hne	253	3	and	and	CC
cord-006460-3ayc0hne	253	4	confusing	confusing	JJ
cord-006460-3ayc0hne	253	5	concept	concept	NN
cord-006460-3ayc0hne	253	6	of	of	IN
cord-006460-3ayc0hne	253	7	organ	organ	NN
cord-006460-3ayc0hne	253	8	damage	damage	NN
cord-006460-3ayc0hne	253	9	is	be	VBZ
cord-006460-3ayc0hne	253	10	recent	recent	JJ
cord-006460-3ayc0hne	253	11	evidence	evidence	NN
cord-006460-3ayc0hne	253	12	that	that	IN
cord-006460-3ayc0hne	253	13	the	the	DT
cord-006460-3ayc0hne	253	14	mesenteric	mesenteric	JJ
cord-006460-3ayc0hne	253	15	lymph	lymph	NN
cord-006460-3ayc0hne	253	16	of	of	IN
cord-006460-3ayc0hne	253	17	animals	animal	NNS
cord-006460-3ayc0hne	253	18	in	in	IN
cord-006460-3ayc0hne	253	19	shock	shock	NN
cord-006460-3ayc0hne	253	20	is	be	VBZ
cord-006460-3ayc0hne	253	21	toxic	toxic	JJ
cord-006460-3ayc0hne	253	22	and	and	CC
cord-006460-3ayc0hne	253	23	,	,	,
cord-006460-3ayc0hne	253	24	when	when	WRB
cord-006460-3ayc0hne	253	25	it	-PRON-	PRP
cord-006460-3ayc0hne	253	26	returns	return	VBZ
cord-006460-3ayc0hne	253	27	to	to	IN
cord-006460-3ayc0hne	253	28	the	the	DT
cord-006460-3ayc0hne	253	29	central	central	JJ
cord-006460-3ayc0hne	253	30	circulation	circulation	NN
cord-006460-3ayc0hne	253	31	,	,	,
cord-006460-3ayc0hne	253	32	it	-PRON-	PRP
cord-006460-3ayc0hne	253	33	activates	activate	VBZ
cord-006460-3ayc0hne	253	34	neutrophils	neutrophil	NNS
cord-006460-3ayc0hne	253	35	which	which	WDT
cord-006460-3ayc0hne	253	36	produce	produce	VBP
cord-006460-3ayc0hne	253	37	cell	cell	NN
cord-006460-3ayc0hne	253	38	dam	dam	NN
cord-006460-3ayc0hne	253	39	-	-	HYPH
cord-006460-3ayc0hne	253	40	age	age	NN
cord-006460-3ayc0hne	253	41	[	[	-LRB-
cord-006460-3ayc0hne	253	42	71	71	CD
cord-006460-3ayc0hne	253	43	]	]	-RRB-
cord-006460-3ayc0hne	253	44	.	.	.
cord-006460-3ayc0hne	254	1	In	in	IN
cord-006460-3ayc0hne	254	2	a	a	DT
cord-006460-3ayc0hne	254	3	clinical	clinical	JJ
cord-006460-3ayc0hne	254	4	study	study	NN
cord-006460-3ayc0hne	254	5	,	,	,
cord-006460-3ayc0hne	254	6	thoracic	thoracic	JJ
cord-006460-3ayc0hne	254	7	lymph	lymph	NN
cord-006460-3ayc0hne	254	8	was	be	VBD
cord-006460-3ayc0hne	254	9	diverted	divert	VBN
cord-006460-3ayc0hne	254	10	and	and	CC
cord-006460-3ayc0hne	254	11	sampled	sample	VBN
cord-006460-3ayc0hne	254	12	in	in	IN
cord-006460-3ayc0hne	254	13	patients	patient	NNS
cord-006460-3ayc0hne	254	14	with	with	IN
cord-006460-3ayc0hne	254	15	MOF	MOF	NNP
cord-006460-3ayc0hne	254	16	and	and	CC
cord-006460-3ayc0hne	254	17	no	no	DT
cord-006460-3ayc0hne	254	18	toxicity	toxicity	NN
cord-006460-3ayc0hne	254	19	was	be	VBD
cord-006460-3ayc0hne	254	20	found	find	VBN
cord-006460-3ayc0hne	254	21	[	[	-LRB-
cord-006460-3ayc0hne	254	22	72	72	CD
cord-006460-3ayc0hne	254	23	]	]	-RRB-
cord-006460-3ayc0hne	254	24	.	.	.
cord-006460-3ayc0hne	255	1	Others	other	NNS
cord-006460-3ayc0hne	255	2	found	find	VBD
cord-006460-3ayc0hne	255	3	that	that	IN
cord-006460-3ayc0hne	255	4	mesenteric	mesenteric	JJ
cord-006460-3ayc0hne	255	5	lymph	lymph	NN
cord-006460-3ayc0hne	255	6	is	be	VBZ
cord-006460-3ayc0hne	255	7	a	a	DT
cord-006460-3ayc0hne	255	8	problem	problem	NN
cord-006460-3ayc0hne	255	9	and	and	CC
cord-006460-3ayc0hne	255	10	this	this	DT
cord-006460-3ayc0hne	255	11	must	must	MD
cord-006460-3ayc0hne	255	12	be	be	VB
cord-006460-3ayc0hne	255	13	explored	explore	VBN
cord-006460-3ayc0hne	255	14	further	far	RBR
cord-006460-3ayc0hne	255	15	in	in	IN
cord-006460-3ayc0hne	255	16	order	order	NN
cord-006460-3ayc0hne	255	17	to	to	TO
cord-006460-3ayc0hne	255	18	ascertain	ascertain	VB
cord-006460-3ayc0hne	255	19	what	what	WP
cord-006460-3ayc0hne	255	20	its	-PRON-	PRP$
cord-006460-3ayc0hne	255	21	consequences	consequence	NNS
cord-006460-3ayc0hne	255	22	are	be	VBP
cord-006460-3ayc0hne	255	23	in	in	IN
cord-006460-3ayc0hne	255	24	man	man	NN
cord-006460-3ayc0hne	255	25	[	[	-LRB-
cord-006460-3ayc0hne	255	26	73	73	CD
cord-006460-3ayc0hne	255	27	,	,	,
cord-006460-3ayc0hne	255	28	74	74	CD
cord-006460-3ayc0hne	255	29	]	]	-RRB-
cord-006460-3ayc0hne	255	30	.	.	.
cord-006460-3ayc0hne	256	1	In	in	IN
cord-006460-3ayc0hne	256	2	experimental	experimental	JJ
cord-006460-3ayc0hne	256	3	animals	animal	NNS
cord-006460-3ayc0hne	256	4	,	,	,
cord-006460-3ayc0hne	256	5	there	there	EX
cord-006460-3ayc0hne	256	6	seems	seem	VBZ
cord-006460-3ayc0hne	256	7	little	little	JJ
cord-006460-3ayc0hne	256	8	doubt	doubt	NN
cord-006460-3ayc0hne	256	9	about	about	IN
cord-006460-3ayc0hne	256	10	this	this	DT
cord-006460-3ayc0hne	256	11	phenomenon	phenomenon	NN
cord-006460-3ayc0hne	256	12	[	[	-LRB-
cord-006460-3ayc0hne	256	13	75	75	CD
cord-006460-3ayc0hne	256	14	]	]	-RRB-
cord-006460-3ayc0hne	256	15	.	.	.
cord-006460-3ayc0hne	257	1	Postimplantation	postimplantation	NN
cord-006460-3ayc0hne	257	2	inflammation	inflammation	NN
cord-006460-3ayc0hne	257	3	has	have	VBZ
cord-006460-3ayc0hne	257	4	been	be	VBN
cord-006460-3ayc0hne	257	5	described	describe	VBN
cord-006460-3ayc0hne	257	6	by	by	IN
cord-006460-3ayc0hne	257	7	Zimmer	Zimmer	NNP
cord-006460-3ayc0hne	257	8	et	et	NNP
cord-006460-3ayc0hne	257	9	al	al	NNP
cord-006460-3ayc0hne	257	10	.	.	.
cord-006460-3ayc0hne	258	1	[	[	-LRB-
cord-006460-3ayc0hne	258	2	76	76	CD
cord-006460-3ayc0hne	258	3	]	]	-RRB-
cord-006460-3ayc0hne	258	4	.	.	.
cord-006460-3ayc0hne	259	1	The	the	DT
cord-006460-3ayc0hne	259	2	implantation	implantation	NN
cord-006460-3ayc0hne	259	3	of	of	IN
cord-006460-3ayc0hne	259	4	a	a	DT
cord-006460-3ayc0hne	259	5	device	device	NN
cord-006460-3ayc0hne	259	6	in	in	IN
cord-006460-3ayc0hne	259	7	a	a	DT
cord-006460-3ayc0hne	259	8	patient	patient	NN
cord-006460-3ayc0hne	259	9	produces	produce	VBZ
cord-006460-3ayc0hne	259	10	an	an	DT
cord-006460-3ayc0hne	259	11	inflammatory	inflammatory	JJ
cord-006460-3ayc0hne	259	12	reaction	reaction	NN
cord-006460-3ayc0hne	259	13	that	that	WDT
cord-006460-3ayc0hne	259	14	can	can	MD
cord-006460-3ayc0hne	259	15	be	be	VB
cord-006460-3ayc0hne	259	16	quite	quite	RB
cord-006460-3ayc0hne	259	17	severe	severe	JJ
cord-006460-3ayc0hne	259	18	.	.	.
cord-006460-3ayc0hne	260	1	There	there	EX
cord-006460-3ayc0hne	260	2	is	be	VBZ
cord-006460-3ayc0hne	260	3	also	also	RB
cord-006460-3ayc0hne	260	4	a	a	DT
cord-006460-3ayc0hne	260	5	question	question	NN
cord-006460-3ayc0hne	260	6	as	as	IN
cord-006460-3ayc0hne	260	7	to	to	IN
cord-006460-3ayc0hne	260	8	whether	whether	IN
cord-006460-3ayc0hne	260	9	we	-PRON-	PRP
cord-006460-3ayc0hne	260	10	should	should	MD
cord-006460-3ayc0hne	260	11	replace	replace	VB
cord-006460-3ayc0hne	260	12	rather	rather	RB
cord-006460-3ayc0hne	260	13	than	than	IN
cord-006460-3ayc0hne	260	14	block	block	VB
cord-006460-3ayc0hne	260	15	various	various	JJ
cord-006460-3ayc0hne	260	16	mediators	mediator	NNS
cord-006460-3ayc0hne	260	17	.	.	.
cord-006460-3ayc0hne	261	1	For	for	IN
cord-006460-3ayc0hne	261	2	example	example	NN
cord-006460-3ayc0hne	261	3	,	,	,
cord-006460-3ayc0hne	261	4	increasing	increase	VBG
cord-006460-3ayc0hne	261	5	the	the	DT
cord-006460-3ayc0hne	261	6	level	level	NN
cord-006460-3ayc0hne	261	7	of	of	IN
cord-006460-3ayc0hne	261	8	protein	protein	NN
cord-006460-3ayc0hne	261	9	C	c	NN
cord-006460-3ayc0hne	261	10	could	could	MD
cord-006460-3ayc0hne	261	11	be	be	VB
cord-006460-3ayc0hne	261	12	helpful	helpful	JJ
cord-006460-3ayc0hne	261	13	.	.	.
cord-006460-3ayc0hne	262	1	There	there	EX
cord-006460-3ayc0hne	262	2	is	be	VBZ
cord-006460-3ayc0hne	262	3	a	a	DT
cord-006460-3ayc0hne	262	4	question	question	NN
cord-006460-3ayc0hne	262	5	as	as	IN
cord-006460-3ayc0hne	262	6	to	to	IN
cord-006460-3ayc0hne	262	7	whether	whether	IN
cord-006460-3ayc0hne	262	8	transgenic	transgenic	JJ
cord-006460-3ayc0hne	262	9	knockout	knockout	NN
cord-006460-3ayc0hne	262	10	animals	animal	NNS
cord-006460-3ayc0hne	262	11	,	,	,
cord-006460-3ayc0hne	262	12	which	which	WDT
cord-006460-3ayc0hne	262	13	provide	provide	VBP
cord-006460-3ayc0hne	262	14	fascinating	fascinating	JJ
cord-006460-3ayc0hne	262	15	information	information	NN
cord-006460-3ayc0hne	262	16	,	,	,
cord-006460-3ayc0hne	262	17	will	will	MD
cord-006460-3ayc0hne	262	18	explain	explain	VB
cord-006460-3ayc0hne	262	19	the	the	DT
cord-006460-3ayc0hne	262	20	redundancies	redundancy	NNS
cord-006460-3ayc0hne	262	21	,	,	,
cord-006460-3ayc0hne	262	22	the	the	DT
cord-006460-3ayc0hne	262	23	overlap	overlap	NN
cord-006460-3ayc0hne	262	24	,	,	,
cord-006460-3ayc0hne	262	25	and	and	CC
cord-006460-3ayc0hne	262	26	the	the	DT
cord-006460-3ayc0hne	262	27	interactions	interaction	NNS
cord-006460-3ayc0hne	262	28	between	between	IN
cord-006460-3ayc0hne	262	29	cytokines	cytokine	NNS
cord-006460-3ayc0hne	262	30	and	and	CC
cord-006460-3ayc0hne	262	31	various	various	JJ
cord-006460-3ayc0hne	262	32	other	other	JJ
cord-006460-3ayc0hne	262	33	mediators	mediator	NNS
cord-006460-3ayc0hne	262	34	.	.	.
cord-006460-3ayc0hne	263	1	They	-PRON-	PRP
cord-006460-3ayc0hne	263	2	may	may	MD
cord-006460-3ayc0hne	263	3	not	not	RB
cord-006460-3ayc0hne	263	4	be	be	VB
cord-006460-3ayc0hne	263	5	able	able	JJ
cord-006460-3ayc0hne	263	6	to	to	TO
cord-006460-3ayc0hne	263	7	indicate	indicate	VB
cord-006460-3ayc0hne	263	8	the	the	DT
cord-006460-3ayc0hne	263	9	problems	problem	NNS
cord-006460-3ayc0hne	263	10	of	of	IN
cord-006460-3ayc0hne	263	11	cell	cell	NN
cord-006460-3ayc0hne	263	12	-	-	HYPH
cord-006460-3ayc0hne	263	13	cell	cell	NN
cord-006460-3ayc0hne	263	14	interaction	interaction	NN
cord-006460-3ayc0hne	263	15	such	such	JJ
cord-006460-3ayc0hne	263	16	as	as	IN
cord-006460-3ayc0hne	263	17	the	the	DT
cord-006460-3ayc0hne	263	18	interactions	interaction	NNS
cord-006460-3ayc0hne	263	19	between	between	IN
cord-006460-3ayc0hne	263	20	neutrophils	neutrophil	NNS
cord-006460-3ayc0hne	263	21	and	and	CC
cord-006460-3ayc0hne	263	22	platelets	platelet	NNS
cord-006460-3ayc0hne	263	23	[	[	-LRB-
cord-006460-3ayc0hne	263	24	77	77	CD
cord-006460-3ayc0hne	263	25	]	]	-RRB-
cord-006460-3ayc0hne	263	26	.	.	.
cord-006460-3ayc0hne	264	1	Polymerase	polymerase	NN
cord-006460-3ayc0hne	264	2	chain	chain	NN
cord-006460-3ayc0hne	264	3	reaction	reaction	NN
cord-006460-3ayc0hne	264	4	(	(	-LRB-
cord-006460-3ayc0hne	264	5	PCR	PCR	NNP
cord-006460-3ayc0hne	264	6	)	)	-RRB-
cord-006460-3ayc0hne	264	7	will	will	MD
cord-006460-3ayc0hne	264	8	contribute	contribute	VB
cord-006460-3ayc0hne	264	9	greatly	greatly	RB
cord-006460-3ayc0hne	264	10	to	to	IN
cord-006460-3ayc0hne	264	11	our	-PRON-	PRP$
cord-006460-3ayc0hne	264	12	understanding	understanding	NN
cord-006460-3ayc0hne	264	13	of	of	IN
cord-006460-3ayc0hne	264	14	human	human	JJ
cord-006460-3ayc0hne	264	15	disease	disease	NN
cord-006460-3ayc0hne	264	16	[	[	-LRB-
cord-006460-3ayc0hne	264	17	78	78	CD
cord-006460-3ayc0hne	264	18	]	]	-RRB-
cord-006460-3ayc0hne	264	19	.	.	.
cord-006460-3ayc0hne	265	1	PCR	PCR	NNP
cord-006460-3ayc0hne	265	2	detects	detect	VBZ
cord-006460-3ayc0hne	265	3	microbial	microbial	JJ
cord-006460-3ayc0hne	265	4	DNA	dna	NN
cord-006460-3ayc0hne	265	5	in	in	IN
cord-006460-3ayc0hne	265	6	blood	blood	NN
cord-006460-3ayc0hne	265	7	and	and	CC
cord-006460-3ayc0hne	265	8	is	be	VBZ
cord-006460-3ayc0hne	265	9	much	much	RB
cord-006460-3ayc0hne	265	10	more	more	RBR
cord-006460-3ayc0hne	265	11	sensitive	sensitive	JJ
cord-006460-3ayc0hne	265	12	than	than	IN
cord-006460-3ayc0hne	265	13	blood	blood	NN
cord-006460-3ayc0hne	265	14	cultures	culture	NNS
cord-006460-3ayc0hne	265	15	.	.	.
cord-006460-3ayc0hne	266	1	A	a	DT
cord-006460-3ayc0hne	266	2	consensus	consensus	NN
cord-006460-3ayc0hne	266	3	PCR	PCR	NNP
cord-006460-3ayc0hne	266	4	will	will	MD
cord-006460-3ayc0hne	266	5	provide	provide	VB
cord-006460-3ayc0hne	266	6	information	information	NN
cord-006460-3ayc0hne	266	7	about	about	IN
cord-006460-3ayc0hne	266	8	shared	share	VBD
cord-006460-3ayc0hne	266	9	conserved	conserved	JJ
cord-006460-3ayc0hne	266	10	genetic	genetic	JJ
cord-006460-3ayc0hne	266	11	sequences	sequence	NNS
cord-006460-3ayc0hne	266	12	.	.	.
cord-006460-3ayc0hne	267	1	There	there	EX
cord-006460-3ayc0hne	267	2	is	be	VBZ
cord-006460-3ayc0hne	267	3	also	also	RB
cord-006460-3ayc0hne	267	4	representational	representational	JJ
cord-006460-3ayc0hne	267	5	difference	difference	NN
cord-006460-3ayc0hne	267	6	analysis	analysis	NN
cord-006460-3ayc0hne	267	7	(	(	-LRB-
cord-006460-3ayc0hne	267	8	RDA	RDA	NNP
cord-006460-3ayc0hne	267	9	)	)	-RRB-
cord-006460-3ayc0hne	267	10	and	and	CC
cord-006460-3ayc0hne	267	11	pathogen	pathogen	NN
cord-006460-3ayc0hne	267	12	detection	detection	NN
cord-006460-3ayc0hne	267	13	chips	chip	NNS
cord-006460-3ayc0hne	267	14	.	.	.
cord-006460-3ayc0hne	268	1	DNA	dna	NN
cord-006460-3ayc0hne	268	2	microarray	microarray	NN
cord-006460-3ayc0hne	268	3	techniques	technique	NNS
cord-006460-3ayc0hne	268	4	and	and	CC
cord-006460-3ayc0hne	268	5	gene	gene	NN
cord-006460-3ayc0hne	268	6	expression	expression	NN
cord-006460-3ayc0hne	268	7	immune	immune	JJ
cord-006460-3ayc0hne	268	8	cells	cell	NNS
cord-006460-3ayc0hne	268	9	will	will	MD
cord-006460-3ayc0hne	268	10	provide	provide	VB
cord-006460-3ayc0hne	268	11	similar	similar	JJ
cord-006460-3ayc0hne	268	12	responses	response	NNS
cord-006460-3ayc0hne	268	13	.	.	.
cord-006460-3ayc0hne	269	1	It	-PRON-	PRP
cord-006460-3ayc0hne	269	2	is	be	VBZ
cord-006460-3ayc0hne	269	3	possible	possible	JJ
cord-006460-3ayc0hne	269	4	,	,	,
cord-006460-3ayc0hne	269	5	in	in	IN
cord-006460-3ayc0hne	269	6	the	the	DT
cord-006460-3ayc0hne	269	7	future	future	NN
cord-006460-3ayc0hne	269	8	,	,	,
cord-006460-3ayc0hne	269	9	that	that	IN
cord-006460-3ayc0hne	269	10	everyone	everyone	NN
cord-006460-3ayc0hne	269	11	with	with	IN
cord-006460-3ayc0hne	269	12	sepsis	sepsis	NN
cord-006460-3ayc0hne	269	13	or	or	CC
cord-006460-3ayc0hne	269	14	SIRS	SIRS	NNP
cord-006460-3ayc0hne	269	15	may	may	MD
cord-006460-3ayc0hne	269	16	be	be	VB
cord-006460-3ayc0hne	269	17	found	find	VBN
cord-006460-3ayc0hne	269	18	to	to	TO
cord-006460-3ayc0hne	269	19	have	have	VB
cord-006460-3ayc0hne	269	20	an	an	DT
cord-006460-3ayc0hne	269	21	infection	infection	NN
cord-006460-3ayc0hne	269	22	of	of	IN
cord-006460-3ayc0hne	269	23	some	some	DT
cord-006460-3ayc0hne	269	24	sort	sort	NN
cord-006460-3ayc0hne	269	25	,	,	,
cord-006460-3ayc0hne	269	26	a	a	DT
cord-006460-3ayc0hne	269	27	virus	virus	NN
cord-006460-3ayc0hne	269	28	which	which	WDT
cord-006460-3ayc0hne	269	29	can	can	MD
cord-006460-3ayc0hne	269	30	not	not	RB
cord-006460-3ayc0hne	269	31	be	be	VB
cord-006460-3ayc0hne	269	32	cultured	culture	VBN
cord-006460-3ayc0hne	269	33	,	,	,
cord-006460-3ayc0hne	269	34	bacteria	bacteria	NNS
cord-006460-3ayc0hne	269	35	which	which	WDT
cord-006460-3ayc0hne	269	36	can	can	MD
cord-006460-3ayc0hne	269	37	not	not	RB
cord-006460-3ayc0hne	269	38	be	be	VB
cord-006460-3ayc0hne	269	39	cultured	cultured	JJ
cord-006460-3ayc0hne	269	40	,	,	,
cord-006460-3ayc0hne	269	41	or	or	CC
cord-006460-3ayc0hne	269	42	some	some	DT
cord-006460-3ayc0hne	269	43	other	other	JJ
cord-006460-3ayc0hne	269	44	microbial	microbial	JJ
cord-006460-3ayc0hne	269	45	factor	factor	NN
cord-006460-3ayc0hne	269	46	[	[	-LRB-
cord-006460-3ayc0hne	269	47	79	79	CD
cord-006460-3ayc0hne	269	48	,	,	,
cord-006460-3ayc0hne	269	49	80	80	CD
cord-006460-3ayc0hne	269	50	,	,	,
cord-006460-3ayc0hne	269	51	81	81	CD
cord-006460-3ayc0hne	269	52	]	]	-RRB-
cord-006460-3ayc0hne	269	53	.	.	.
cord-006460-3ayc0hne	270	1	Other	other	JJ
cord-006460-3ayc0hne	270	2	new	new	JJ
cord-006460-3ayc0hne	270	3	concepts	concept	NNS
cord-006460-3ayc0hne	270	4	of	of	IN
cord-006460-3ayc0hne	270	5	organ	organ	NN
cord-006460-3ayc0hne	270	6	damage	damage	NN
cord-006460-3ayc0hne	270	7	include	include	VBP
cord-006460-3ayc0hne	270	8	superantigen	superantigen	NN
cord-006460-3ayc0hne	270	9	-	-	HYPH
cord-006460-3ayc0hne	270	10	mediated	mediate	VBN
cord-006460-3ayc0hne	270	11	lethal	lethal	JJ
cord-006460-3ayc0hne	270	12	shock	shock	NN
cord-006460-3ayc0hne	270	13	[	[	-LRB-
cord-006460-3ayc0hne	270	14	82	82	CD
cord-006460-3ayc0hne	270	15	]	]	-RRB-
cord-006460-3ayc0hne	270	16	.	.	.
cord-006460-3ayc0hne	271	1	The	the	DT
cord-006460-3ayc0hne	271	2	bacteria	bacteria	NNS
cord-006460-3ayc0hne	271	3	H.	h.	NN
cord-006460-3ayc0hne	271	4	pylori	pylori	NN
cord-006460-3ayc0hne	271	5	produces	produce	VBZ
cord-006460-3ayc0hne	271	6	gastric	gastric	JJ
cord-006460-3ayc0hne	271	7	ulcer	ulcer	NN
cord-006460-3ayc0hne	271	8	and	and	CC
cord-006460-3ayc0hne	271	9	duodenal	duodenal	JJ
cord-006460-3ayc0hne	271	10	ulcer	ulcer	NN
cord-006460-3ayc0hne	271	11	disease	disease	NN
cord-006460-3ayc0hne	271	12	,	,	,
cord-006460-3ayc0hne	271	13	and	and	CC
cord-006460-3ayc0hne	271	14	perhaps	perhaps	RB
cord-006460-3ayc0hne	271	15	gastric	gastric	JJ
cord-006460-3ayc0hne	271	16	cancer	cancer	NN
cord-006460-3ayc0hne	271	17	.	.	.
cord-006460-3ayc0hne	272	1	Does	do	VBZ
cord-006460-3ayc0hne	272	2	H.	H.	NNP
cord-006460-3ayc0hne	272	3	pylori	pylori	NN
cord-006460-3ayc0hne	272	4	modulate	modulate	VB
cord-006460-3ayc0hne	272	5	the	the	DT
cord-006460-3ayc0hne	272	6	response	response	NN
cord-006460-3ayc0hne	272	7	to	to	IN
cord-006460-3ayc0hne	272	8	injury	injury	NN
cord-006460-3ayc0hne	272	9	and	and	CC
cord-006460-3ayc0hne	272	10	is	be	VBZ
cord-006460-3ayc0hne	272	11	it	-PRON-	PRP
cord-006460-3ayc0hne	272	12	a	a	DT
cord-006460-3ayc0hne	272	13	nosocomial	nosocomial	JJ
cord-006460-3ayc0hne	272	14	infection	infection	NN
cord-006460-3ayc0hne	272	15	[	[	-LRB-
cord-006460-3ayc0hne	272	16	83	83	CD
cord-006460-3ayc0hne	272	17	,	,	,
cord-006460-3ayc0hne	272	18	84	84	CD
cord-006460-3ayc0hne	272	19	]	]	-RRB-
cord-006460-3ayc0hne	272	20	?	?	.
cord-006460-3ayc0hne	273	1	It	-PRON-	PRP
cord-006460-3ayc0hne	273	2	is	be	VBZ
cord-006460-3ayc0hne	273	3	known	know	VBN
cord-006460-3ayc0hne	273	4	that	that	IN
cord-006460-3ayc0hne	273	5	neutrophils	neutrophil	NNS
cord-006460-3ayc0hne	273	6	in	in	IN
cord-006460-3ayc0hne	273	7	the	the	DT
cord-006460-3ayc0hne	273	8	inflammatory	inflammatory	JJ
cord-006460-3ayc0hne	273	9	response	response	NN
cord-006460-3ayc0hne	273	10	are	be	VBP
cord-006460-3ayc0hne	273	11	both	both	CC
cord-006460-3ayc0hne	273	12	a	a	DT
cord-006460-3ayc0hne	273	13	culprit	culprit	NN
cord-006460-3ayc0hne	273	14	and	and	CC
cord-006460-3ayc0hne	273	15	a	a	DT
cord-006460-3ayc0hne	273	16	solution	solution	NN
cord-006460-3ayc0hne	273	17	with	with	IN
cord-006460-3ayc0hne	273	18	delayed	delay	VBN
cord-006460-3ayc0hne	273	19	apoptosis	apoptosis	NN
cord-006460-3ayc0hne	273	20	,	,	,
cord-006460-3ayc0hne	273	21	cytotoxicity	cytotoxicity	NN
cord-006460-3ayc0hne	273	22	,	,	,
cord-006460-3ayc0hne	273	23	activation	activation	NN
cord-006460-3ayc0hne	273	24	of	of	IN
cord-006460-3ayc0hne	273	25	neutrophils	neutrophil	NNS
cord-006460-3ayc0hne	273	26	,	,	,
cord-006460-3ayc0hne	273	27	and	and	CC
cord-006460-3ayc0hne	273	28	the	the	DT
cord-006460-3ayc0hne	273	29	production	production	NN
cord-006460-3ayc0hne	273	30	and	and	CC
cord-006460-3ayc0hne	273	31	release	release	NN
cord-006460-3ayc0hne	273	32	of	of	IN
cord-006460-3ayc0hne	273	33	elastase	elastase	NN
cord-006460-3ayc0hne	273	34	and	and	CC
cord-006460-3ayc0hne	273	35	superoxide	superoxide	NN
cord-006460-3ayc0hne	273	36	anions	anion	NNS
cord-006460-3ayc0hne	273	37	,	,	,
cord-006460-3ayc0hne	273	38	which	which	WDT
cord-006460-3ayc0hne	273	39	damage	damage	NN
cord-006460-3ayc0hne	273	40	cells	cell	NNS
cord-006460-3ayc0hne	273	41	[	[	-LRB-
cord-006460-3ayc0hne	273	42	87	87	CD
cord-006460-3ayc0hne	273	43	,	,	,
cord-006460-3ayc0hne	273	44	88	88	CD
cord-006460-3ayc0hne	273	45	]	]	-RRB-
cord-006460-3ayc0hne	273	46	.	.	.
cord-006460-3ayc0hne	274	1	The	the	DT
cord-006460-3ayc0hne	274	2	effect	effect	NN
cord-006460-3ayc0hne	274	3	of	of	IN
cord-006460-3ayc0hne	274	4	granulocyte	granulocyte	NN
cord-006460-3ayc0hne	274	5	colony	colony	NN
cord-006460-3ayc0hne	274	6	-	-	HYPH
cord-006460-3ayc0hne	274	7	stimulating	stimulate	VBG
cord-006460-3ayc0hne	274	8	factor	factor	NN
cord-006460-3ayc0hne	274	9	(	(	-LRB-
cord-006460-3ayc0hne	274	10	G	G	NNP
cord-006460-3ayc0hne	274	11	-	-	HYPH
cord-006460-3ayc0hne	274	12	CSF	CSF	NNP
cord-006460-3ayc0hne	274	13	)	)	-RRB-
cord-006460-3ayc0hne	274	14	is	be	VBZ
cord-006460-3ayc0hne	274	15	important	important	JJ
cord-006460-3ayc0hne	274	16	.	.	.
cord-006460-3ayc0hne	275	1	For	for	IN
cord-006460-3ayc0hne	275	2	example	example	NN
cord-006460-3ayc0hne	275	3	,	,	,
cord-006460-3ayc0hne	275	4	the	the	DT
cord-006460-3ayc0hne	275	5	use	use	NN
cord-006460-3ayc0hne	275	6	of	of	IN
cord-006460-3ayc0hne	275	7	neupogen	neupogen	NNP
cord-006460-3ayc0hne	275	8	,	,	,
cord-006460-3ayc0hne	275	9	a	a	DT
cord-006460-3ayc0hne	275	10	G	G	NNP
cord-006460-3ayc0hne	275	11	-	-	HYPH
cord-006460-3ayc0hne	275	12	CSF	csf	NN
cord-006460-3ayc0hne	275	13	compound	compound	NN
cord-006460-3ayc0hne	275	14	,	,	,
cord-006460-3ayc0hne	275	15	is	be	VBZ
cord-006460-3ayc0hne	275	16	encouraging	encourage	VBG
cord-006460-3ayc0hne	275	17	[	[	-LRB-
cord-006460-3ayc0hne	275	18	89	89	CD
cord-006460-3ayc0hne	275	19	]	]	-RRB-
cord-006460-3ayc0hne	275	20	,	,	,
cord-006460-3ayc0hne	275	21	whereas	whereas	IN
cord-006460-3ayc0hne	275	22	Root	Root	NNP
cord-006460-3ayc0hne	275	23	[	[	-LRB-
cord-006460-3ayc0hne	275	24	90	90	CD
cord-006460-3ayc0hne	275	25	]	]	-RRB-
cord-006460-3ayc0hne	275	26	reported	report	VBD
cord-006460-3ayc0hne	275	27	that	that	IN
cord-006460-3ayc0hne	275	28	rG	rg	NN
cord-006460-3ayc0hne	275	29	-	-	HYPH
cord-006460-3ayc0hne	275	30	CSF	csf	NN
cord-006460-3ayc0hne	275	31	(	(	-LRB-
cord-006460-3ayc0hne	275	32	filgrastin	filgrastin	NN
cord-006460-3ayc0hne	275	33	)	)	-RRB-
cord-006460-3ayc0hne	275	34	did	do	VBD
cord-006460-3ayc0hne	275	35	not	not	RB
cord-006460-3ayc0hne	275	36	alter	alter	VB
cord-006460-3ayc0hne	275	37	morbidity	morbidity	NN
cord-006460-3ayc0hne	275	38	or	or	CC
cord-006460-3ayc0hne	275	39	mortality	mortality	NN
cord-006460-3ayc0hne	275	40	in	in	IN
cord-006460-3ayc0hne	275	41	the	the	DT
cord-006460-3ayc0hne	275	42	treatment	treatment	NN
cord-006460-3ayc0hne	275	43	of	of	IN
cord-006460-3ayc0hne	275	44	pneumonia	pneumonia	NN
cord-006460-3ayc0hne	275	45	,	,	,
cord-006460-3ayc0hne	275	46	sepsis	sepsis	NN
cord-006460-3ayc0hne	275	47	and	and	CC
cord-006460-3ayc0hne	275	48	septic	septic	JJ
cord-006460-3ayc0hne	275	49	shock	shock	NN
cord-006460-3ayc0hne	275	50	[	[	-LRB-
cord-006460-3ayc0hne	275	51	89	89	CD
cord-006460-3ayc0hne	275	52	]	]	-RRB-
cord-006460-3ayc0hne	275	53	.	.	.
cord-006460-3ayc0hne	276	1	There	there	EX
cord-006460-3ayc0hne	276	2	is	be	VBZ
cord-006460-3ayc0hne	276	3	considerable	considerable	JJ
cord-006460-3ayc0hne	276	4	information	information	NN
cord-006460-3ayc0hne	276	5	about	about	IN
cord-006460-3ayc0hne	276	6	these	these	DT
cord-006460-3ayc0hne	276	7	factors	factor	NNS
cord-006460-3ayc0hne	276	8	,	,	,
cord-006460-3ayc0hne	276	9	but	but	CC
cord-006460-3ayc0hne	276	10	what	what	WP
cord-006460-3ayc0hne	276	11	to	to	TO
cord-006460-3ayc0hne	276	12	do	do	VB
cord-006460-3ayc0hne	276	13	about	about	IN
cord-006460-3ayc0hne	276	14	them	-PRON-	PRP
cord-006460-3ayc0hne	276	15	is	be	VBZ
cord-006460-3ayc0hne	276	16	far	far	RB
cord-006460-3ayc0hne	276	17	from	from	IN
cord-006460-3ayc0hne	276	18	being	be	VBG
cord-006460-3ayc0hne	276	19	established	establish	VBN
cord-006460-3ayc0hne	276	20	.	.	.
cord-006460-3ayc0hne	277	1	These	these	DT
cord-006460-3ayc0hne	277	2	are	be	VBP
cord-006460-3ayc0hne	277	3	presently	presently	RB
cord-006460-3ayc0hne	277	4	imponderables	imponderable	NNS
cord-006460-3ayc0hne	277	5	.	.	.
cord-006460-3ayc0hne	278	1	The	the	DT
cord-006460-3ayc0hne	278	2	timing	timing	NN
cord-006460-3ayc0hne	278	3	of	of	IN
cord-006460-3ayc0hne	278	4	treatments	treatment	NNS
cord-006460-3ayc0hne	278	5	is	be	VBZ
cord-006460-3ayc0hne	278	6	critical	critical	JJ
cord-006460-3ayc0hne	278	7	.	.	.
cord-006460-3ayc0hne	279	1	For	for	IN
cord-006460-3ayc0hne	279	2	example	example	NN
cord-006460-3ayc0hne	279	3	,	,	,
cord-006460-3ayc0hne	279	4	Knox	Knox	NNP
cord-006460-3ayc0hne	279	5	et	et	NNP
cord-006460-3ayc0hne	279	6	al	al	NNP
cord-006460-3ayc0hne	279	7	.	.	.
cord-006460-3ayc0hne	280	1	[	[	-LRB-
cord-006460-3ayc0hne	280	2	91	91	CD
cord-006460-3ayc0hne	280	3	]	]	-RRB-
cord-006460-3ayc0hne	280	4	found	find	VBD
cord-006460-3ayc0hne	280	5	that	that	IN
cord-006460-3ayc0hne	280	6	recombinant	recombinant	JJ
cord-006460-3ayc0hne	280	7	human	human	JJ
cord-006460-3ayc0hne	280	8	growth	growth	NN
cord-006460-3ayc0hne	280	9	hormone	hormone	NN
cord-006460-3ayc0hne	280	10	(	(	-LRB-
cord-006460-3ayc0hne	280	11	rHGH	rhgh	NN
cord-006460-3ayc0hne	280	12	)	)	-RRB-
cord-006460-3ayc0hne	280	13	can	can	MD
cord-006460-3ayc0hne	280	14	be	be	VB
cord-006460-3ayc0hne	280	15	helpful	helpful	JJ
cord-006460-3ayc0hne	280	16	in	in	IN
cord-006460-3ayc0hne	280	17	burns	burn	NNS
cord-006460-3ayc0hne	280	18	when	when	WRB
cord-006460-3ayc0hne	280	19	given	give	VBN
cord-006460-3ayc0hne	280	20	at	at	IN
cord-006460-3ayc0hne	280	21	an	an	DT
cord-006460-3ayc0hne	280	22	appropriate	appropriate	JJ
cord-006460-3ayc0hne	280	23	time	time	NN
cord-006460-3ayc0hne	280	24	;	;	:
cord-006460-3ayc0hne	280	25	however	however	RB
cord-006460-3ayc0hne	280	26	,	,	,
cord-006460-3ayc0hne	280	27	in	in	IN
cord-006460-3ayc0hne	280	28	other	other	JJ
cord-006460-3ayc0hne	280	29	studies	study	NNS
cord-006460-3ayc0hne	280	30	,	,	,
cord-006460-3ayc0hne	280	31	it	-PRON-	PRP
cord-006460-3ayc0hne	280	32	was	be	VBD
cord-006460-3ayc0hne	280	33	found	find	VBN
cord-006460-3ayc0hne	280	34	to	to	TO
cord-006460-3ayc0hne	280	35	increase	increase	VB
cord-006460-3ayc0hne	280	36	mortality	mortality	NN
cord-006460-3ayc0hne	280	37	.	.	.
cord-006460-3ayc0hne	281	1	The	the	DT
cord-006460-3ayc0hne	281	2	relationships	relationship	NNS
cord-006460-3ayc0hne	281	3	of	of	IN
cord-006460-3ayc0hne	281	4	infec	infec	NN
cord-006460-3ayc0hne	281	5	-	-	HYPH
cord-006460-3ayc0hne	281	6	tion	tion	NN
cord-006460-3ayc0hne	281	7	and	and	CC
cord-006460-3ayc0hne	281	8	cancer	cancer	NN
cord-006460-3ayc0hne	281	9	are	be	VBP
cord-006460-3ayc0hne	281	10	becoming	become	VBG
cord-006460-3ayc0hne	281	11	increasingly	increasingly	RB
cord-006460-3ayc0hne	281	12	apparent	apparent	JJ
cord-006460-3ayc0hne	281	13	.	.	.
cord-006460-3ayc0hne	282	1	Hepatitis	Hepatitis	NNP
cord-006460-3ayc0hne	282	2	B	B	NNP
cord-006460-3ayc0hne	282	3	,	,	,
cord-006460-3ayc0hne	282	4	H.	H.	NNP
cord-006460-3ayc0hne	282	5	pylori	pylori	NN
cord-006460-3ayc0hne	282	6	,	,	.
cord-006460-3ayc0hne	283	1	the	the	DT
cord-006460-3ayc0hne	283	2	Lyme	Lyme	NNP
cord-006460-3ayc0hne	283	3	disease	disease	NN
cord-006460-3ayc0hne	283	4	spirochete	spirochete	NN
cord-006460-3ayc0hne	283	5	and	and	CC
cord-006460-3ayc0hne	283	6	other	other	JJ
cord-006460-3ayc0hne	283	7	organisms	organism	NNS
cord-006460-3ayc0hne	283	8	are	be	VBP
cord-006460-3ayc0hne	283	9	associated	associate	VBN
cord-006460-3ayc0hne	283	10	with	with	IN
cord-006460-3ayc0hne	283	11	increased	increase	VBN
cord-006460-3ayc0hne	283	12	incidence	incidence	NN
cord-006460-3ayc0hne	283	13	of	of	IN
cord-006460-3ayc0hne	283	14	certain	certain	JJ
cord-006460-3ayc0hne	283	15	malignancies	malignancy	NNS
cord-006460-3ayc0hne	283	16	.	.	.
cord-006460-3ayc0hne	284	1	Patients	patient	NNS
cord-006460-3ayc0hne	284	2	with	with	IN
cord-006460-3ayc0hne	284	3	short	short	JJ
cord-006460-3ayc0hne	284	4	-	-	HYPH
cord-006460-3ayc0hne	284	5	bowel	bowel	NN
cord-006460-3ayc0hne	284	6	syndrome	syndrome	NN
cord-006460-3ayc0hne	284	7	have	have	VBP
cord-006460-3ayc0hne	284	8	benefited	benefit	VBN
cord-006460-3ayc0hne	284	9	from	from	IN
cord-006460-3ayc0hne	284	10	rHGH	rHGH	NNS
cord-006460-3ayc0hne	284	11	[	[	-LRB-
cord-006460-3ayc0hne	284	12	92	92	CD
cord-006460-3ayc0hne	284	13	]	]	-RRB-
cord-006460-3ayc0hne	284	14	,	,	,
cord-006460-3ayc0hne	284	15	as	as	IN
cord-006460-3ayc0hne	284	16	have	have	VBP
cord-006460-3ayc0hne	284	17	patients	patient	NNS
cord-006460-3ayc0hne	284	18	with	with	IN
cord-006460-3ayc0hne	284	19	burns	burn	NNS
cord-006460-3ayc0hne	284	20	[	[	-LRB-
cord-006460-3ayc0hne	284	21	93	93	CD
cord-006460-3ayc0hne	284	22	]	]	-RRB-
cord-006460-3ayc0hne	284	23	.	.	.
cord-006460-3ayc0hne	285	1	A	a	DT
cord-006460-3ayc0hne	285	2	multicenter	multicenter	JJ
cord-006460-3ayc0hne	285	3	phase	phase	NN
cord-006460-3ayc0hne	285	4	III	iii	CD
cord-006460-3ayc0hne	285	5	trial	trial	NN
cord-006460-3ayc0hne	285	6	in	in	IN
cord-006460-3ayc0hne	285	7	Europe	Europe	NNP
cord-006460-3ayc0hne	285	8	administered	administer	VBD
cord-006460-3ayc0hne	285	9	rHGH	rHGH	''
cord-006460-3ayc0hne	285	10	to	to	IN
cord-006460-3ayc0hne	285	11	patients	patient	NNS
cord-006460-3ayc0hne	285	12	after	after	IN
cord-006460-3ayc0hne	285	13	operations	operation	NNS
cord-006460-3ayc0hne	285	14	,	,	,
cord-006460-3ayc0hne	285	15	trauma	trauma	NN
cord-006460-3ayc0hne	285	16	or	or	CC
cord-006460-3ayc0hne	285	17	with	with	IN
cord-006460-3ayc0hne	285	18	ARDS	ARDS	NNP
cord-006460-3ayc0hne	285	19	and	and	CC
cord-006460-3ayc0hne	285	20	after	after	IN
cord-006460-3ayc0hne	285	21	5	5	CD
cord-006460-3ayc0hne	285	22	days	day	NNS
cord-006460-3ayc0hne	285	23	of	of	IN
cord-006460-3ayc0hne	285	24	intensive	intensive	JJ
cord-006460-3ayc0hne	285	25	care	care	NN
cord-006460-3ayc0hne	285	26	.	.	.
cord-006460-3ayc0hne	286	1	The	the	DT
cord-006460-3ayc0hne	286	2	company	company	NN
cord-006460-3ayc0hne	286	3	allegedly	allegedly	RB
cord-006460-3ayc0hne	286	4	called	call	VBD
cord-006460-3ayc0hne	286	5	off	off	RP
cord-006460-3ayc0hne	286	6	the	the	DT
cord-006460-3ayc0hne	286	7	trial	trial	NN
cord-006460-3ayc0hne	286	8	because	because	IN
cord-006460-3ayc0hne	286	9	of	of	IN
cord-006460-3ayc0hne	286	10	a	a	DT
cord-006460-3ayc0hne	286	11	twofold	twofold	JJ
cord-006460-3ayc0hne	286	12	increase	increase	NN
cord-006460-3ayc0hne	286	13	in	in	IN
cord-006460-3ayc0hne	286	14	mortality	mortality	NN
cord-006460-3ayc0hne	286	15	in	in	IN
cord-006460-3ayc0hne	286	16	the	the	DT
cord-006460-3ayc0hne	286	17	treated	treated	JJ
cord-006460-3ayc0hne	286	18	group	group	NN
cord-006460-3ayc0hne	286	19	.	.	.
cord-006460-3ayc0hne	287	1	This	this	DT
cord-006460-3ayc0hne	287	2	has	have	VBZ
cord-006460-3ayc0hne	287	3	not	not	RB
cord-006460-3ayc0hne	287	4	been	be	VBN
cord-006460-3ayc0hne	287	5	reported	report	VBN
cord-006460-3ayc0hne	287	6	yet	yet	RB
cord-006460-3ayc0hne	288	1	(	(	-LRB-
cord-006460-3ayc0hne	288	2	D.	D.	NNP
cord-006460-3ayc0hne	288	3	Wilmore	Wilmore	NNP
cord-006460-3ayc0hne	288	4	,	,	,
cord-006460-3ayc0hne	288	5	pers	pers	NNP
cord-006460-3ayc0hne	288	6	.	.	NNP
cord-006460-3ayc0hne	288	7	comm	comm	NNP
cord-006460-3ayc0hne	288	8	.	.	.
cord-006460-3ayc0hne	288	9	)	)	-RRB-
cord-006460-3ayc0hne	288	10	.	.	.
cord-006460-3ayc0hne	289	1	There	there	EX
cord-006460-3ayc0hne	289	2	are	be	VBP
cord-006460-3ayc0hne	289	3	other	other	JJ
cord-006460-3ayc0hne	289	4	differences	difference	NNS
cord-006460-3ayc0hne	289	5	that	that	WDT
cord-006460-3ayc0hne	289	6	must	must	MD
cord-006460-3ayc0hne	289	7	be	be	VB
cord-006460-3ayc0hne	289	8	considered	consider	VBN
cord-006460-3ayc0hne	289	9	.	.	.
cord-006460-3ayc0hne	290	1	For	for	IN
cord-006460-3ayc0hne	290	2	example	example	NN
cord-006460-3ayc0hne	290	3	,	,	,
cord-006460-3ayc0hne	290	4	the	the	DT
cord-006460-3ayc0hne	290	5	neutrophil	neutrophil	NN
cord-006460-3ayc0hne	290	6	response	response	NN
cord-006460-3ayc0hne	290	7	to	to	IN
cord-006460-3ayc0hne	290	8	trauma	trauma	NN
cord-006460-3ayc0hne	290	9	depends	depend	VBZ
cord-006460-3ayc0hne	290	10	on	on	IN
cord-006460-3ayc0hne	290	11	the	the	DT
cord-006460-3ayc0hne	290	12	bacterial	bacterial	JJ
cord-006460-3ayc0hne	290	13	species	specie	NNS
cord-006460-3ayc0hne	290	14	.	.	.
cord-006460-3ayc0hne	291	1	In	in	IN
cord-006460-3ayc0hne	291	2	addition	addition	NN
cord-006460-3ayc0hne	291	3	,	,	,
cord-006460-3ayc0hne	291	4	septic	septic	JJ
cord-006460-3ayc0hne	291	5	serum	serum	NN
cord-006460-3ayc0hne	291	6	signaling	signaling	NN
cord-006460-3ayc0hne	291	7	is	be	VBZ
cord-006460-3ayc0hne	291	8	diverse	diverse	JJ
cord-006460-3ayc0hne	291	9	and	and	CC
cord-006460-3ayc0hne	291	10	complex	complex	JJ
cord-006460-3ayc0hne	291	11	[	[	-LRB-
cord-006460-3ayc0hne	291	12	94	94	CD
cord-006460-3ayc0hne	291	13	]	]	-RRB-
cord-006460-3ayc0hne	291	14	.	.	.
cord-006460-3ayc0hne	292	1	Genes	gene	NNS
cord-006460-3ayc0hne	292	2	are	be	VBP
cord-006460-3ayc0hne	292	3	expressed	express	VBN
cord-006460-3ayc0hne	292	4	in	in	IN
cord-006460-3ayc0hne	292	5	the	the	DT
cord-006460-3ayc0hne	292	6	serum	serum	NN
cord-006460-3ayc0hne	292	7	of	of	IN
cord-006460-3ayc0hne	292	8	septic	septic	JJ
cord-006460-3ayc0hne	292	9	patients	patient	NNS
cord-006460-3ayc0hne	292	10	which	which	WDT
cord-006460-3ayc0hne	292	11	were	be	VBD
cord-006460-3ayc0hne	292	12	not	not	RB
cord-006460-3ayc0hne	292	13	previously	previously	RB
cord-006460-3ayc0hne	292	14	associated	associate	VBN
cord-006460-3ayc0hne	292	15	with	with	IN
cord-006460-3ayc0hne	292	16	sepsis	sepsis	NN
cord-006460-3ayc0hne	292	17	or	or	CC
cord-006460-3ayc0hne	292	18	known	know	VBN
cord-006460-3ayc0hne	292	19	to	to	TO
cord-006460-3ayc0hne	292	20	have	have	VB
cord-006460-3ayc0hne	292	21	any	any	DT
cord-006460-3ayc0hne	292	22	relationship	relationship	NN
cord-006460-3ayc0hne	292	23	with	with	IN
cord-006460-3ayc0hne	292	24	sepsis	sepsis	NN
cord-006460-3ayc0hne	292	25	.	.	.
cord-006460-3ayc0hne	293	1	Other	other	JJ
cord-006460-3ayc0hne	293	2	differences	difference	NNS
cord-006460-3ayc0hne	293	3	include	include	VBP
cord-006460-3ayc0hne	293	4	:	:	:
cord-006460-3ayc0hne	293	5	AB	AB	NNP
cord-006460-3ayc0hne	293	6	T	T	NNP
cord-006460-3ayc0hne	293	7	-	-	HYPH
cord-006460-3ayc0hne	293	8	cell	cell	NN
cord-006460-3ayc0hne	293	9	receptor	receptor	NN
cord-006460-3ayc0hne	293	10	diversity	diversity	NN
cord-006460-3ayc0hne	293	11	differences	difference	NNS
cord-006460-3ayc0hne	293	12	in	in	IN
cord-006460-3ayc0hne	293	13	species	species	NN
cord-006460-3ayc0hne	293	14	sensitivity	sensitivity	NN
cord-006460-3ayc0hne	293	15	of	of	IN
cord-006460-3ayc0hne	293	16	hormones	hormone	NNS
cord-006460-3ayc0hne	293	17	;	;	:
cord-006460-3ayc0hne	293	18	variability	variability	NN
cord-006460-3ayc0hne	293	19	in	in	IN
cord-006460-3ayc0hne	293	20	the	the	DT
cord-006460-3ayc0hne	293	21	G	G	NNP
cord-006460-3ayc0hne	293	22	-	-	HYPH
cord-006460-3ayc0hne	293	23	CSF	csf	NN
cord-006460-3ayc0hne	293	24	response	response	NN
cord-006460-3ayc0hne	293	25	;	;	:
cord-006460-3ayc0hne	293	26	and	and	CC
cord-006460-3ayc0hne	293	27	LPS	LPS	NNP
cord-006460-3ayc0hne	293	28	stress	stress	NN
cord-006460-3ayc0hne	293	29	variability	variability	NN
cord-006460-3ayc0hne	293	30	in	in	IN
cord-006460-3ayc0hne	293	31	various	various	JJ
cord-006460-3ayc0hne	293	32	species	specie	NNS
cord-006460-3ayc0hne	293	33	.	.	.
cord-006460-3ayc0hne	294	1	An	an	DT
cord-006460-3ayc0hne	294	2	additional	additional	JJ
cord-006460-3ayc0hne	294	3	problem	problem	NN
cord-006460-3ayc0hne	294	4	is	be	VBZ
cord-006460-3ayc0hne	294	5	that	that	DT
cord-006460-3ayc0hne	294	6	of	of	IN
cord-006460-3ayc0hne	294	7	autoimmunity	autoimmunity	NN
cord-006460-3ayc0hne	294	8	,	,	,
cord-006460-3ayc0hne	294	9	which	which	WDT
cord-006460-3ayc0hne	294	10	may	may	MD
cord-006460-3ayc0hne	294	11	be	be	VB
cord-006460-3ayc0hne	294	12	related	relate	VBN
cord-006460-3ayc0hne	294	13	to	to	IN
cord-006460-3ayc0hne	294	14	molecular	molecular	JJ
cord-006460-3ayc0hne	294	15	mimicry	mimicry	NN
cord-006460-3ayc0hne	294	16	.	.	.
cord-006460-3ayc0hne	295	1	Albert	Albert	NNP
cord-006460-3ayc0hne	295	2	et	et	NNP
cord-006460-3ayc0hne	295	3	al	al	NNP
cord-006460-3ayc0hne	295	4	.	.	.
cord-006460-3ayc0hne	296	1	[	[	-LRB-
cord-006460-3ayc0hne	296	2	95	95	CD
cord-006460-3ayc0hne	296	3	]	]	-RRB-
cord-006460-3ayc0hne	296	4	recently	recently	RB
cord-006460-3ayc0hne	296	5	described	describe	VBD
cord-006460-3ayc0hne	296	6	the	the	DT
cord-006460-3ayc0hne	296	7	relationship	relationship	NN
cord-006460-3ayc0hne	296	8	that	that	WDT
cord-006460-3ayc0hne	296	9	may	may	MD
cord-006460-3ayc0hne	296	10	pertain	pertain	VB
cord-006460-3ayc0hne	296	11	.	.	.
cord-006460-3ayc0hne	297	1	For	for	IN
cord-006460-3ayc0hne	297	2	example	example	NN
cord-006460-3ayc0hne	297	3	,	,	,
cord-006460-3ayc0hne	297	4	if	if	IN
cord-006460-3ayc0hne	297	5	the	the	DT
cord-006460-3ayc0hne	297	6	host	host	NN
cord-006460-3ayc0hne	297	7	acquires	acquire	VBZ
cord-006460-3ayc0hne	297	8	an	an	DT
cord-006460-3ayc0hne	297	9	infection	infection	NN
cord-006460-3ayc0hne	297	10	with	with	IN
cord-006460-3ayc0hne	297	11	an	an	DT
cord-006460-3ayc0hne	297	12	agent	agent	NN
cord-006460-3ayc0hne	297	13	that	that	WDT
cord-006460-3ayc0hne	297	14	has	have	VBZ
cord-006460-3ayc0hne	297	15	an	an	DT
cord-006460-3ayc0hne	297	16	antigen	antigen	NN
cord-006460-3ayc0hne	297	17	similar	similar	JJ
cord-006460-3ayc0hne	297	18	to	to	IN
cord-006460-3ayc0hne	297	19	host	host	NN
cord-006460-3ayc0hne	297	20	antigens	antigen	NNS
cord-006460-3ayc0hne	297	21	,	,	,
cord-006460-3ayc0hne	297	22	tolerance	tolerance	NN
cord-006460-3ayc0hne	297	23	to	to	IN
cord-006460-3ayc0hne	297	24	the	the	DT
cord-006460-3ayc0hne	297	25	autoantigens	autoantigens	NNP
cord-006460-3ayc0hne	297	26	may	may	MD
cord-006460-3ayc0hne	297	27	break	break	VB
cord-006460-3ayc0hne	297	28	down	down	RP
cord-006460-3ayc0hne	297	29	.	.	.
cord-006460-3ayc0hne	298	1	The	the	DT
cord-006460-3ayc0hne	298	2	pathogen	pathogen	NN
cord-006460-3ayc0hne	298	3	response	response	NN
cord-006460-3ayc0hne	298	4	then	then	RB
cord-006460-3ayc0hne	298	5	cross	cross	NN
cord-006460-3ayc0hne	298	6	-	-	VBZ
cord-006460-3ayc0hne	298	7	reacts	react	VBZ
cord-006460-3ayc0hne	298	8	to	to	TO
cord-006460-3ayc0hne	298	9	cause	cause	VB
cord-006460-3ayc0hne	298	10	tissue	tissue	NN
cord-006460-3ayc0hne	298	11	damage	damage	NN
cord-006460-3ayc0hne	298	12	and	and	CC
cord-006460-3ayc0hne	298	13	an	an	DT
cord-006460-3ayc0hne	298	14	autoimmune	autoimmune	JJ
cord-006460-3ayc0hne	298	15	response	response	NN
cord-006460-3ayc0hne	298	16	.	.	.
cord-006460-3ayc0hne	299	1	Are	be	VBP
cord-006460-3ayc0hne	299	2	we	-PRON-	PRP
cord-006460-3ayc0hne	299	3	improving	improve	VBG
cord-006460-3ayc0hne	299	4	patient	patient	JJ
cord-006460-3ayc0hne	299	5	care	care	NN
cord-006460-3ayc0hne	299	6	and	and	CC
cord-006460-3ayc0hne	299	7	,	,	,
cord-006460-3ayc0hne	299	8	if	if	IN
cord-006460-3ayc0hne	299	9	so	so	RB
cord-006460-3ayc0hne	299	10	,	,	,
cord-006460-3ayc0hne	299	11	how	how	WRB
cord-006460-3ayc0hne	299	12	?	?	.
cord-006460-3ayc0hne	300	1	Prevention	prevention	NN
cord-006460-3ayc0hne	300	2	of	of	IN
cord-006460-3ayc0hne	300	3	MOF	MOF	NNP
cord-006460-3ayc0hne	300	4	is	be	VBZ
cord-006460-3ayc0hne	300	5	the	the	DT
cord-006460-3ayc0hne	300	6	goal	goal	NN
cord-006460-3ayc0hne	300	7	.	.	.
cord-006460-3ayc0hne	301	1	We	-PRON-	PRP
cord-006460-3ayc0hne	301	2	know	know	VBP
cord-006460-3ayc0hne	301	3	that	that	IN
cord-006460-3ayc0hne	301	4	we	-PRON-	PRP
cord-006460-3ayc0hne	301	5	can	can	MD
cord-006460-3ayc0hne	301	6	not	not	RB
cord-006460-3ayc0hne	301	7	treat	treat	VB
cord-006460-3ayc0hne	301	8	specifically	specifically	RB
cord-006460-3ayc0hne	301	9	but	but	CC
cord-006460-3ayc0hne	301	10	can	can	MD
cord-006460-3ayc0hne	301	11	only	only	RB
cord-006460-3ayc0hne	301	12	support	support	VB
cord-006460-3ayc0hne	301	13	MOF	MOF	NNP
cord-006460-3ayc0hne	301	14	,	,	,
cord-006460-3ayc0hne	301	15	MODS	MODS	NNP
cord-006460-3ayc0hne	301	16	and	and	CC
cord-006460-3ayc0hne	301	17	SIRS	sir	NNS
cord-006460-3ayc0hne	301	18	;	;	:
cord-006460-3ayc0hne	301	19	therefore	therefore	RB
cord-006460-3ayc0hne	301	20	,	,	,
cord-006460-3ayc0hne	301	21	we	-PRON-	PRP
cord-006460-3ayc0hne	301	22	must	must	MD
cord-006460-3ayc0hne	301	23	prevent	prevent	VB
cord-006460-3ayc0hne	301	24	them	-PRON-	PRP
cord-006460-3ayc0hne	301	25	by	by	IN
cord-006460-3ayc0hne	301	26	means	mean	NNS
cord-006460-3ayc0hne	301	27	of	of	IN
cord-006460-3ayc0hne	301	28	better	well	JJR
cord-006460-3ayc0hne	301	29	patient	patient	JJ
cord-006460-3ayc0hne	301	30	care	care	NN
cord-006460-3ayc0hne	301	31	.	.	.
cord-006460-3ayc0hne	302	1	Are	be	VBP
cord-006460-3ayc0hne	302	2	we	-PRON-	PRP
cord-006460-3ayc0hne	302	3	improving	improve	VBG
cord-006460-3ayc0hne	302	4	patient	patient	JJ
cord-006460-3ayc0hne	302	5	care	care	NN
cord-006460-3ayc0hne	302	6	,	,	,
cord-006460-3ayc0hne	302	7	are	be	VBP
cord-006460-3ayc0hne	302	8	we	-PRON-	PRP
cord-006460-3ayc0hne	302	9	winning	win	VBG
cord-006460-3ayc0hne	302	10	the	the	DT
cord-006460-3ayc0hne	302	11	battle	battle	NN
cord-006460-3ayc0hne	302	12	[	[	-LRB-
cord-006460-3ayc0hne	302	13	96	96	CD
cord-006460-3ayc0hne	302	14	,	,	,
cord-006460-3ayc0hne	302	15	97	97	CD
cord-006460-3ayc0hne	302	16	]	]	-RRB-
cord-006460-3ayc0hne	302	17	,	,	,
cord-006460-3ayc0hne	302	18	and	and	CC
cord-006460-3ayc0hne	302	19	is	be	VBZ
cord-006460-3ayc0hne	302	20	MOF	MOF	NNP
cord-006460-3ayc0hne	302	21	disappearing	disappear	VBG
cord-006460-3ayc0hne	302	22	?	?	.
cord-006460-3ayc0hne	303	1	In	in	IN
cord-006460-3ayc0hne	303	2	Levine	Levine	NNP
cord-006460-3ayc0hne	303	3	et	et	NNP
cord-006460-3ayc0hne	303	4	al	al	NNP
cord-006460-3ayc0hne	303	5	.	.	.
cord-006460-3ayc0hne	304	1	[	[	-LRB-
cord-006460-3ayc0hne	304	2	98	98	CD
cord-006460-3ayc0hne	304	3	]	]	-RRB-
cord-006460-3ayc0hne	304	4	we	-PRON-	PRP
cord-006460-3ayc0hne	304	5	reviewed	review	VBD
cord-006460-3ayc0hne	304	6	this	this	DT
cord-006460-3ayc0hne	304	7	recently	recently	RB
cord-006460-3ayc0hne	304	8	,	,	,
cord-006460-3ayc0hne	304	9	raising	raise	VBG
cord-006460-3ayc0hne	304	10	the	the	DT
cord-006460-3ayc0hne	304	11	question	question	NN
cord-006460-3ayc0hne	304	12	:	:	:
cord-006460-3ayc0hne	304	13	MOF	MOF	NNP
cord-006460-3ayc0hne	304	14	-is	-is	ADD
cord-006460-3ayc0hne	305	1	it	-PRON-	PRP
cord-006460-3ayc0hne	305	2	disappearing	disappear	VBG
cord-006460-3ayc0hne	305	3	?	?	.
cord-006460-3ayc0hne	306	1	Our	-PRON-	PRP$
cord-006460-3ayc0hne	306	2	answer	answer	NN
cord-006460-3ayc0hne	306	3	to	to	IN
cord-006460-3ayc0hne	306	4	this	this	DT
cord-006460-3ayc0hne	306	5	question	question	NN
cord-006460-3ayc0hne	306	6	was	be	VBD
cord-006460-3ayc0hne	306	7	no	no	DT
cord-006460-3ayc0hne	306	8	:	:	:
cord-006460-3ayc0hne	306	9	MOF	MOF	NNP
cord-006460-3ayc0hne	306	10	is	be	VBZ
cord-006460-3ayc0hne	306	11	not	not	RB
cord-006460-3ayc0hne	306	12	disappearing	disappear	VBG
cord-006460-3ayc0hne	306	13	and	and	CC
cord-006460-3ayc0hne	306	14	,	,	,
cord-006460-3ayc0hne	306	15	as	as	IN
cord-006460-3ayc0hne	306	16	we	-PRON-	PRP
cord-006460-3ayc0hne	306	17	help	help	VBP
cord-006460-3ayc0hne	306	18	more	more	RBR
cord-006460-3ayc0hne	306	19	severely	severely	RB
cord-006460-3ayc0hne	306	20	injured	injured	JJ
cord-006460-3ayc0hne	306	21	and	and	CC
cord-006460-3ayc0hne	306	22	sick	sick	JJ
cord-006460-3ayc0hne	306	23	patients	patient	NNS
cord-006460-3ayc0hne	306	24	to	to	TO
cord-006460-3ayc0hne	306	25	survive	survive	VB
cord-006460-3ayc0hne	306	26	,	,	,
cord-006460-3ayc0hne	306	27	MOF	MOF	NNP
cord-006460-3ayc0hne	306	28	may	may	MD
cord-006460-3ayc0hne	306	29	actually	actually	RB
cord-006460-3ayc0hne	306	30	increase	increase	VB
cord-006460-3ayc0hne	306	31	and	and	CC
cord-006460-3ayc0hne	306	32	the	the	DT
cord-006460-3ayc0hne	306	33	mortality	mortality	NN
cord-006460-3ayc0hne	306	34	will	will	MD
cord-006460-3ayc0hne	306	35	remain	remain	VB
cord-006460-3ayc0hne	306	36	high	high	JJ
cord-006460-3ayc0hne	306	37	.	.	.
cord-006460-3ayc0hne	307	1	I	-PRON-	PRP
cord-006460-3ayc0hne	307	2	will	will	MD
cord-006460-3ayc0hne	307	3	now	now	RB
cord-006460-3ayc0hne	307	4	review	review	VB
cord-006460-3ayc0hne	307	5	the	the	DT
cord-006460-3ayc0hne	307	6	evidence	evidence	NN
cord-006460-3ayc0hne	307	7	for	for	IN
cord-006460-3ayc0hne	307	8	this	this	DT
cord-006460-3ayc0hne	307	9	.	.	.
cord-006460-3ayc0hne	308	1	Zimmerman	Zimmerman	NNP
cord-006460-3ayc0hne	308	2	et	et	NNP
cord-006460-3ayc0hne	308	3	al	al	NNP
cord-006460-3ayc0hne	308	4	.	.	.
cord-006460-3ayc0hne	309	1	[	[	-LRB-
cord-006460-3ayc0hne	309	2	99	99	CD
cord-006460-3ayc0hne	309	3	]	]	-RRB-
cord-006460-3ayc0hne	309	4	compared	compare	VBD
cord-006460-3ayc0hne	309	5	the	the	DT
cord-006460-3ayc0hne	309	6	risks	risk	NNS
cord-006460-3ayc0hne	309	7	and	and	CC
cord-006460-3ayc0hne	309	8	outcomes	outcome	NNS
cord-006460-3ayc0hne	309	9	for	for	IN
cord-006460-3ayc0hne	309	10	patients	patient	NNS
cord-006460-3ayc0hne	309	11	with	with	IN
cord-006460-3ayc0hne	309	12	organ	organ	NN
cord-006460-3ayc0hne	309	13	system	system	NN
cord-006460-3ayc0hne	309	14	failure	failure	NN
cord-006460-3ayc0hne	309	15	from	from	IN
cord-006460-3ayc0hne	309	16	1982	1982	CD
cord-006460-3ayc0hne	309	17	to	to	IN
cord-006460-3ayc0hne	309	18	1990	1990	CD
cord-006460-3ayc0hne	309	19	.	.	.
cord-006460-3ayc0hne	310	1	They	-PRON-	PRP
cord-006460-3ayc0hne	310	2	found	find	VBD
cord-006460-3ayc0hne	310	3	that	that	IN
cord-006460-3ayc0hne	310	4	"	"	``
cord-006460-3ayc0hne	310	5	The	the	DT
cord-006460-3ayc0hne	310	6	incidence	incidence	NN
cord-006460-3ayc0hne	310	7	and	and	CC
cord-006460-3ayc0hne	310	8	overall	overall	JJ
cord-006460-3ayc0hne	310	9	outcome	outcome	NN
cord-006460-3ayc0hne	310	10	of	of	IN
cord-006460-3ayc0hne	310	11	organ	organ	NN
cord-006460-3ayc0hne	310	12	system	system	NN
cord-006460-3ayc0hne	310	13	failure	failure	NN
cord-006460-3ayc0hne	310	14	have	have	VBP
cord-006460-3ayc0hne	310	15	not	not	RB
cord-006460-3ayc0hne	310	16	changed	change	VBN
cord-006460-3ayc0hne	310	17	significantly	significantly	RB
cord-006460-3ayc0hne	310	18	over	over	IN
cord-006460-3ayc0hne	310	19	the	the	DT
cord-006460-3ayc0hne	310	20	past	past	JJ
cord-006460-3ayc0hne	310	21	eight	eight	CD
cord-006460-3ayc0hne	310	22	years	year	NNS
cord-006460-3ayc0hne	310	23	.	.	.
cord-006460-3ayc0hne	311	1	There	there	EX
cord-006460-3ayc0hne	311	2	has	have	VBZ
cord-006460-3ayc0hne	311	3	been	be	VBN
cord-006460-3ayc0hne	311	4	significant	significant	JJ
cord-006460-3ayc0hne	311	5	improvement	improvement	NN
cord-006460-3ayc0hne	311	6	in	in	IN
cord-006460-3ayc0hne	311	7	survival	survival	NN
cord-006460-3ayc0hne	311	8	of	of	IN
cord-006460-3ayc0hne	311	9	patients	patient	NNS
cord-006460-3ayc0hne	311	10	with	with	IN
cord-006460-3ayc0hne	311	11	persistent	persistent	JJ
cord-006460-3ayc0hne	311	12	severe	severe	JJ
cord-006460-3ayc0hne	311	13	organ	organ	NN
cord-006460-3ayc0hne	311	14	system	system	NN
cord-006460-3ayc0hne	311	15	failure	failure	NN
cord-006460-3ayc0hne	311	16	.	.	.
cord-006460-3ayc0hne	311	17	"	"	''
cord-006460-3ayc0hne	312	1	Thus	thus	RB
cord-006460-3ayc0hne	312	2	,	,	,
cord-006460-3ayc0hne	312	3	this	this	DT
cord-006460-3ayc0hne	312	4	report	report	NN
cord-006460-3ayc0hne	312	5	confirms	confirm	VBZ
cord-006460-3ayc0hne	312	6	again	again	RB
cord-006460-3ayc0hne	312	7	(	(	-LRB-
cord-006460-3ayc0hne	312	8	1	1	LS
cord-006460-3ayc0hne	312	9	)	)	-RRB-
cord-006460-3ayc0hne	312	10	that	that	WDT
cord-006460-3ayc0hne	312	11	better	well	JJR
cord-006460-3ayc0hne	312	12	intensive	intensive	JJ
cord-006460-3ayc0hne	312	13	care	care	NN
cord-006460-3ayc0hne	312	14	is	be	VBZ
cord-006460-3ayc0hne	312	15	helping	help	VBG
cord-006460-3ayc0hne	312	16	,	,	,
cord-006460-3ayc0hne	312	17	and	and	CC
cord-006460-3ayc0hne	312	18	(	(	-LRB-
cord-006460-3ayc0hne	312	19	2	2	LS
cord-006460-3ayc0hne	312	20	)	)	-RRB-
cord-006460-3ayc0hne	312	21	my	-PRON-	PRP$
cord-006460-3ayc0hne	312	22	insistence	insistence	NN
cord-006460-3ayc0hne	312	23	that	that	IN
cord-006460-3ayc0hne	312	24	the	the	DT
cord-006460-3ayc0hne	312	25	secret	secret	NN
cord-006460-3ayc0hne	312	26	to	to	IN
cord-006460-3ayc0hne	312	27	MOF	MOF	NNP
cord-006460-3ayc0hne	312	28	is	be	VBZ
cord-006460-3ayc0hne	312	29	prevention	prevention	NN
cord-006460-3ayc0hne	312	30	.	.	.
cord-006460-3ayc0hne	313	1	Regel	Regel	NNP
cord-006460-3ayc0hne	313	2	et	et	NNP
cord-006460-3ayc0hne	313	3	al	al	NNP
cord-006460-3ayc0hne	313	4	.	.	.
cord-006460-3ayc0hne	314	1	[	[	-LRB-
cord-006460-3ayc0hne	314	2	101	101	CD
cord-006460-3ayc0hne	314	3	]	]	-RRB-
cord-006460-3ayc0hne	314	4	reported	report	VBN
cord-006460-3ayc0hne	314	5	on	on	IN
cord-006460-3ayc0hne	314	6	the	the	DT
cord-006460-3ayc0hne	314	7	results	result	NNS
cord-006460-3ayc0hne	314	8	of	of	IN
cord-006460-3ayc0hne	314	9	patients	patient	NNS
cord-006460-3ayc0hne	314	10	with	with	IN
cord-006460-3ayc0hne	314	11	multiple	multiple	JJ
cord-006460-3ayc0hne	314	12	trauma	trauma	NN
cord-006460-3ayc0hne	314	13	(	(	-LRB-
cord-006460-3ayc0hne	314	14	3406	3406	CD
cord-006460-3ayc0hne	314	15	patients	patient	NNS
cord-006460-3ayc0hne	314	16	)	)	-RRB-
cord-006460-3ayc0hne	314	17	treated	treat	VBN
cord-006460-3ayc0hne	314	18	between	between	IN
cord-006460-3ayc0hne	314	19	1972	1972	CD
cord-006460-3ayc0hne	314	20	and	and	CC
cord-006460-3ayc0hne	314	21	1991	1991	CD
cord-006460-3ayc0hne	314	22	at	at	IN
cord-006460-3ayc0hne	314	23	a	a	DT
cord-006460-3ayc0hne	314	24	German	german	JJ
cord-006460-3ayc0hne	314	25	level	level	NN
cord-006460-3ayc0hne	314	26	one	one	CD
cord-006460-3ayc0hne	314	27	trauma	trauma	NN
cord-006460-3ayc0hne	314	28	center	center	NN
cord-006460-3ayc0hne	314	29	.	.	.
cord-006460-3ayc0hne	315	1	They	-PRON-	PRP
cord-006460-3ayc0hne	315	2	found	find	VBD
cord-006460-3ayc0hne	315	3	increased	increase	VBN
cord-006460-3ayc0hne	315	4	head	head	NN
cord-006460-3ayc0hne	315	5	and	and	CC
cord-006460-3ayc0hne	315	6	thoracic	thoracic	JJ
cord-006460-3ayc0hne	315	7	injuries	injury	NNS
cord-006460-3ayc0hne	315	8	in	in	IN
cord-006460-3ayc0hne	315	9	the	the	DT
cord-006460-3ayc0hne	315	10	second	second	JJ
cord-006460-3ayc0hne	315	11	decade	decade	NN
cord-006460-3ayc0hne	315	12	.	.	.
cord-006460-3ayc0hne	316	1	In	in	IN
cord-006460-3ayc0hne	316	2	the	the	DT
cord-006460-3ayc0hne	316	3	second	second	JJ
cord-006460-3ayc0hne	316	4	decade	decade	NN
cord-006460-3ayc0hne	316	5	,	,	,
cord-006460-3ayc0hne	316	6	there	there	EX
cord-006460-3ayc0hne	316	7	was	be	VBD
cord-006460-3ayc0hne	316	8	a	a	DT
cord-006460-3ayc0hne	316	9	decrease	decrease	NN
cord-006460-3ayc0hne	316	10	in	in	IN
cord-006460-3ayc0hne	316	11	renal	renal	JJ
cord-006460-3ayc0hne	316	12	failure	failure	NN
cord-006460-3ayc0hne	316	13	and	and	CC
cord-006460-3ayc0hne	316	14	ARDS	ARDS	NNP
cord-006460-3ayc0hne	316	15	,	,	,
cord-006460-3ayc0hne	316	16	but	but	CC
cord-006460-3ayc0hne	316	17	an	an	DT
cord-006460-3ayc0hne	316	18	increase	increase	NN
cord-006460-3ayc0hne	316	19	in	in	IN
cord-006460-3ayc0hne	316	20	MOF	MOF	NNP
cord-006460-3ayc0hne	316	21	from	from	IN
cord-006460-3ayc0hne	316	22	15.4	15.4	CD
cord-006460-3ayc0hne	316	23	to	to	IN
cord-006460-3ayc0hne	316	24	28.2	28.2	CD
cord-006460-3ayc0hne	316	25	%	%	NN
cord-006460-3ayc0hne	316	26	.	.	.
cord-006460-3ayc0hne	317	1	Lethal	lethal	JJ
cord-006460-3ayc0hne	317	2	MOF	MOF	NNP
cord-006460-3ayc0hne	317	3	increased	increase	VBD
cord-006460-3ayc0hne	317	4	from	from	IN
cord-006460-3ayc0hne	317	5	13.8	13.8	CD
cord-006460-3ayc0hne	317	6	to	to	IN
cord-006460-3ayc0hne	317	7	18.6	18.6	CD
cord-006460-3ayc0hne	317	8	%	%	NN
cord-006460-3ayc0hne	317	9	;	;	,
cord-006460-3ayc0hne	317	10	however	however	RB
cord-006460-3ayc0hne	317	11	,	,	,
cord-006460-3ayc0hne	317	12	overall	overall	JJ
cord-006460-3ayc0hne	317	13	mortality	mortality	NN
cord-006460-3ayc0hne	317	14	decreased	decrease	VBD
cord-006460-3ayc0hne	317	15	from	from	IN
cord-006460-3ayc0hne	317	16	37	37	CD
cord-006460-3ayc0hne	317	17	to	to	TO
cord-006460-3ayc0hne	317	18	22	22	CD
cord-006460-3ayc0hne	317	19	%	%	NN
cord-006460-3ayc0hne	317	20	.	.	.
cord-006460-3ayc0hne	318	1	Regel	Regel	NNP
cord-006460-3ayc0hne	318	2	et	et	NNP
cord-006460-3ayc0hne	318	3	al	al	NNP
cord-006460-3ayc0hne	318	4	.	.	NNP
cord-006460-3ayc0hne	318	5	believed	believe	VBD
cord-006460-3ayc0hne	318	6	that	that	IN
cord-006460-3ayc0hne	318	7	more	more	RBR
cord-006460-3ayc0hne	318	8	severely	severely	RB
cord-006460-3ayc0hne	318	9	injured	injure	VBN
cord-006460-3ayc0hne	318	10	patients	patient	NNS
cord-006460-3ayc0hne	318	11	stayed	stay	VBD
cord-006460-3ayc0hne	318	12	alive	alive	JJ
cord-006460-3ayc0hne	318	13	longer	long	RBR
cord-006460-3ayc0hne	318	14	to	to	TO
cord-006460-3ayc0hne	318	15	develop	develop	VB
cord-006460-3ayc0hne	318	16	MOF	MOF	NNP
cord-006460-3ayc0hne	318	17	and	and	CC
cord-006460-3ayc0hne	318	18	then	then	RB
cord-006460-3ayc0hne	318	19	die	die	VB
cord-006460-3ayc0hne	318	20	.	.	.
cord-006460-3ayc0hne	319	1	Christou	Christou	NNP
cord-006460-3ayc0hne	319	2	et	et	NNP
cord-006460-3ayc0hne	319	3	al	al	NNP
cord-006460-3ayc0hne	319	4	.	.	.
cord-006460-3ayc0hne	320	1	[	[	-LRB-
cord-006460-3ayc0hne	320	2	101	101	CD
cord-006460-3ayc0hne	320	3	]	]	-RRB-
cord-006460-3ayc0hne	320	4	reported	report	VBN
cord-006460-3ayc0hne	320	5	on	on	IN
cord-006460-3ayc0hne	320	6	the	the	DT
cord-006460-3ayc0hne	320	7	delayed	delay	VBN
cord-006460-3ayc0hne	320	8	hypersensitivity	hypersensitivity	NN
cord-006460-3ayc0hne	320	9	response	response	NN
cord-006460-3ayc0hne	320	10	and	and	CC
cord-006460-3ayc0hne	320	11	host	host	NN
cord-006460-3ayc0hne	320	12	resistance	resistance	NN
cord-006460-3ayc0hne	320	13	in	in	IN
cord-006460-3ayc0hne	320	14	surgical	surgical	JJ
cord-006460-3ayc0hne	320	15	patients	patient	NNS
cord-006460-3ayc0hne	320	16	,	,	,
cord-006460-3ayc0hne	320	17	and	and	CC
cord-006460-3ayc0hne	320	18	on	on	IN
cord-006460-3ayc0hne	320	19	the	the	DT
cord-006460-3ayc0hne	320	20	results	result	NNS
cord-006460-3ayc0hne	320	21	of	of	IN
cord-006460-3ayc0hne	320	22	surgical	surgical	JJ
cord-006460-3ayc0hne	320	23	care	care	NN
cord-006460-3ayc0hne	320	24	over	over	IN
cord-006460-3ayc0hne	320	25	a	a	DT
cord-006460-3ayc0hne	320	26	20-year	20-year	JJ
cord-006460-3ayc0hne	320	27	period	period	NN
cord-006460-3ayc0hne	320	28	.	.	.
cord-006460-3ayc0hne	321	1	They	-PRON-	PRP
cord-006460-3ayc0hne	321	2	found	find	VBD
cord-006460-3ayc0hne	321	3	that	that	IN
cord-006460-3ayc0hne	321	4	overall	overall	JJ
cord-006460-3ayc0hne	321	5	surgical	surgical	JJ
cord-006460-3ayc0hne	321	6	mortality	mortality	NN
cord-006460-3ayc0hne	321	7	decreased	decrease	VBD
cord-006460-3ayc0hne	321	8	from	from	IN
cord-006460-3ayc0hne	321	9	11.4	11.4	CD
cord-006460-3ayc0hne	321	10	%	%	NN
cord-006460-3ayc0hne	321	11	in	in	IN
cord-006460-3ayc0hne	321	12	the	the	DT
cord-006460-3ayc0hne	321	13	1970s	1970	NNS
cord-006460-3ayc0hne	321	14	to	to	IN
cord-006460-3ayc0hne	321	15	10.2	10.2	CD
cord-006460-3ayc0hne	321	16	%	%	NN
cord-006460-3ayc0hne	321	17	in	in	IN
cord-006460-3ayc0hne	321	18	the	the	DT
cord-006460-3ayc0hne	321	19	1980s	1980	NNS
cord-006460-3ayc0hne	321	20	and	and	CC
cord-006460-3ayc0hne	321	21	to	to	IN
cord-006460-3ayc0hne	321	22	2.4	2.4	CD
cord-006460-3ayc0hne	321	23	%	%	NN
cord-006460-3ayc0hne	321	24	in	in	IN
cord-006460-3ayc0hne	321	25	the	the	DT
cord-006460-3ayc0hne	321	26	1990s	1990s	CD
cord-006460-3ayc0hne	321	27	.	.	.
cord-006460-3ayc0hne	322	1	They	-PRON-	PRP
cord-006460-3ayc0hne	322	2	believe	believe	VBP
cord-006460-3ayc0hne	322	3	that	that	IN
cord-006460-3ayc0hne	322	4	this	this	DT
cord-006460-3ayc0hne	322	5	was	be	VBD
cord-006460-3ayc0hne	322	6	due	due	JJ
cord-006460-3ayc0hne	322	7	to	to	IN
cord-006460-3ayc0hne	322	8	improved	improve	VBN
cord-006460-3ayc0hne	322	9	pre-	pre-	JJ
cord-006460-3ayc0hne	322	10	,	,	,
cord-006460-3ayc0hne	322	11	post	post	JJ
cord-006460-3ayc0hne	322	12	-	-	JJ
cord-006460-3ayc0hne	322	13	and	and	CC
cord-006460-3ayc0hne	322	14	intra	intra	JJ
cord-006460-3ayc0hne	322	15	-	-	JJ
cord-006460-3ayc0hne	322	16	operative	operative	JJ
cord-006460-3ayc0hne	322	17	care	care	NN
cord-006460-3ayc0hne	322	18	.	.	.
cord-006460-3ayc0hne	323	1	However	however	RB
cord-006460-3ayc0hne	323	2	,	,	,
cord-006460-3ayc0hne	323	3	there	there	EX
cord-006460-3ayc0hne	323	4	was	be	VBD
cord-006460-3ayc0hne	323	5	no	no	DT
cord-006460-3ayc0hne	323	6	decrease	decrease	NN
cord-006460-3ayc0hne	323	7	in	in	IN
cord-006460-3ayc0hne	323	8	surgical	surgical	JJ
cord-006460-3ayc0hne	323	9	ICU	ICU	NNP
cord-006460-3ayc0hne	323	10	deaths	death	NNS
cord-006460-3ayc0hne	323	11	.	.	.
cord-006460-3ayc0hne	324	1	The	the	DT
cord-006460-3ayc0hne	324	2	ICU	ICU	NNP
cord-006460-3ayc0hne	324	3	remains	remain	VBZ
cord-006460-3ayc0hne	324	4	a	a	DT
cord-006460-3ayc0hne	324	5	problem	problem	NN
cord-006460-3ayc0hne	324	6	.	.	.
cord-006460-3ayc0hne	325	1	O'Keefe	O'Keefe	NNP
cord-006460-3ayc0hne	325	2	et	et	NNP
cord-006460-3ayc0hne	325	3	al	al	NNP
cord-006460-3ayc0hne	325	4	.	.	.
cord-006460-3ayc0hne	326	1	[	[	-LRB-
cord-006460-3ayc0hne	326	2	102	102	CD
cord-006460-3ayc0hne	326	3	]	]	-RRB-
cord-006460-3ayc0hne	326	4	reported	report	VBD
cord-006460-3ayc0hne	326	5	10-year	10-year	CD
cord-006460-3ayc0hne	326	6	trends	trend	NNS
cord-006460-3ayc0hne	326	7	in	in	IN
cord-006460-3ayc0hne	326	8	costs	cost	NNS
cord-006460-3ayc0hne	326	9	,	,	,
cord-006460-3ayc0hne	326	10	resource	resource	NN
cord-006460-3ayc0hne	326	11	utilization	utilization	NN
cord-006460-3ayc0hne	326	12	and	and	CC
cord-006460-3ayc0hne	326	13	survival	survival	NN
cord-006460-3ayc0hne	326	14	in	in	IN
cord-006460-3ayc0hne	326	15	an	an	DT
cord-006460-3ayc0hne	326	16	established	establish	VBN
cord-006460-3ayc0hne	326	17	trauma	trauma	NN
cord-006460-3ayc0hne	326	18	center	center	NN
cord-006460-3ayc0hne	326	19	.	.	.
cord-006460-3ayc0hne	327	1	They	-PRON-	PRP
cord-006460-3ayc0hne	327	2	found	find	VBD
cord-006460-3ayc0hne	327	3	no	no	DT
cord-006460-3ayc0hne	327	4	change	change	NN
cord-006460-3ayc0hne	327	5	in	in	IN
cord-006460-3ayc0hne	327	6	mean	mean	JJ
cord-006460-3ayc0hne	327	7	age	age	NN
cord-006460-3ayc0hne	327	8	or	or	CC
cord-006460-3ayc0hne	327	9	ISS	ISS	NNP
cord-006460-3ayc0hne	327	10	over	over	IN
cord-006460-3ayc0hne	327	11	the	the	DT
cord-006460-3ayc0hne	327	12	10-year	10-year	CD
cord-006460-3ayc0hne	327	13	period	period	NN
cord-006460-3ayc0hne	327	14	.	.	.
cord-006460-3ayc0hne	328	1	Crude	crude	JJ
cord-006460-3ayc0hne	328	2	mortality	mortality	NN
cord-006460-3ayc0hne	328	3	did	do	VBD
cord-006460-3ayc0hne	328	4	not	not	RB
cord-006460-3ayc0hne	328	5	change	change	VB
cord-006460-3ayc0hne	328	6	.	.	.
cord-006460-3ayc0hne	329	1	It	-PRON-	PRP
cord-006460-3ayc0hne	329	2	stayed	stay	VBD
cord-006460-3ayc0hne	329	3	at	at	IN
cord-006460-3ayc0hne	329	4	8	8	CD
cord-006460-3ayc0hne	329	5	%	%	NN
cord-006460-3ayc0hne	329	6	.	.	.
cord-006460-3ayc0hne	330	1	Length	length	NN
cord-006460-3ayc0hne	330	2	of	of	IN
cord-006460-3ayc0hne	330	3	stay	stay	NN
cord-006460-3ayc0hne	330	4	decreased	decrease	VBD
cord-006460-3ayc0hne	330	5	from	from	IN
cord-006460-3ayc0hne	330	6	9.5	9.5	CD
cord-006460-3ayc0hne	330	7	to	to	TO
cord-006460-3ayc0hne	330	8	6.8	6.8	CD
cord-006460-3ayc0hne	330	9	days	day	NNS
cord-006460-3ayc0hne	330	10	,	,	,
cord-006460-3ayc0hne	330	11	while	while	IN
cord-006460-3ayc0hne	330	12	costs	cost	NNS
cord-006460-3ayc0hne	330	13	increased	increase	VBN
cord-006460-3ayc0hne	330	14	by	by	IN
cord-006460-3ayc0hne	330	15	16.7	16.7	CD
cord-006460-3ayc0hne	330	16	%	%	NN
cord-006460-3ayc0hne	330	17	.	.	.
cord-006460-3ayc0hne	331	1	Adjusting	adjust	VBG
cord-006460-3ayc0hne	331	2	for	for	IN
cord-006460-3ayc0hne	331	3	ISS	ISS	NNP
cord-006460-3ayc0hne	331	4	and	and	CC
cord-006460-3ayc0hne	331	5	accidental	accidental	JJ
cord-006460-3ayc0hne	331	6	injury	injury	NN
cord-006460-3ayc0hne	331	7	score	score	NN
cord-006460-3ayc0hne	331	8	,	,	,
cord-006460-3ayc0hne	331	9	the	the	DT
cord-006460-3ayc0hne	331	10	mortality	mortality	NN
cord-006460-3ayc0hne	331	11	decreased	decrease	VBD
cord-006460-3ayc0hne	331	12	by	by	IN
cord-006460-3ayc0hne	331	13	3%/year	3%/year	CD
cord-006460-3ayc0hne	331	14	in	in	IN
cord-006460-3ayc0hne	331	15	patients	patient	NNS
cord-006460-3ayc0hne	331	16	with	with	IN
cord-006460-3ayc0hne	331	17	an	an	DT
cord-006460-3ayc0hne	331	18	ISS	ISS	NNP
cord-006460-3ayc0hne	331	19	>	>	XX
cord-006460-3ayc0hne	331	20	16	16	CD
cord-006460-3ayc0hne	331	21	.	.	.
cord-006460-3ayc0hne	332	1	Thus	thus	RB
cord-006460-3ayc0hne	332	2	,	,	,
cord-006460-3ayc0hne	332	3	to	to	TO
cord-006460-3ayc0hne	332	4	answer	answer	VB
cord-006460-3ayc0hne	332	5	the	the	DT
cord-006460-3ayc0hne	332	6	question	question	NN
cord-006460-3ayc0hne	332	7	-is	-is	:
cord-006460-3ayc0hne	332	8	MOF	MOF	NNP
cord-006460-3ayc0hne	332	9	disappearing	disappear	VBG
cord-006460-3ayc0hne	332	10	?	?	.
cord-006460-3ayc0hne	333	1	-	-	:
cord-006460-3ayc0hne	333	2	,	,	,
cord-006460-3ayc0hne	333	3	in	in	IN
cord-006460-3ayc0hne	333	4	the	the	DT
cord-006460-3ayc0hne	333	5	last	last	JJ
cord-006460-3ayc0hne	333	6	decade	decade	NN
cord-006460-3ayc0hne	333	7	the	the	DT
cord-006460-3ayc0hne	333	8	incidence	incidence	NN
cord-006460-3ayc0hne	333	9	varied	varied	JJ
cord-006460-3ayc0hne	333	10	from	from	IN
cord-006460-3ayc0hne	333	11	2	2	CD
cord-006460-3ayc0hne	333	12	to	to	IN
cord-006460-3ayc0hne	333	13	25	25	CD
cord-006460-3ayc0hne	333	14	%	%	NN
cord-006460-3ayc0hne	333	15	,	,	,
cord-006460-3ayc0hne	333	16	depending	depend	VBG
cord-006460-3ayc0hne	333	17	on	on	IN
cord-006460-3ayc0hne	333	18	the	the	DT
cord-006460-3ayc0hne	333	19	clinical	clinical	JJ
cord-006460-3ayc0hne	333	20	setting	setting	NN
cord-006460-3ayc0hne	333	21	,	,	,
cord-006460-3ayc0hne	333	22	with	with	IN
cord-006460-3ayc0hne	333	23	a	a	DT
cord-006460-3ayc0hne	333	24	mortality	mortality	NN
cord-006460-3ayc0hne	333	25	rate	rate	NN
cord-006460-3ayc0hne	333	26	of	of	IN
cord-006460-3ayc0hne	333	27	40	40	CD
cord-006460-3ayc0hne	333	28	-	-	SYM
cord-006460-3ayc0hne	333	29	80	80	CD
cord-006460-3ayc0hne	333	30	%	%	NN
cord-006460-3ayc0hne	333	31	.	.	.
cord-006460-3ayc0hne	334	1	Regel	Regel	NNP
cord-006460-3ayc0hne	334	2	et	et	NNP
cord-006460-3ayc0hne	334	3	al	al	NNP
cord-006460-3ayc0hne	334	4	.	.	.
cord-006460-3ayc0hne	335	1	[	[	-LRB-
cord-006460-3ayc0hne	335	2	100	100	CD
cord-006460-3ayc0hne	335	3	]	]	-RRB-
cord-006460-3ayc0hne	335	4	found	find	VBD
cord-006460-3ayc0hne	335	5	that	that	IN
cord-006460-3ayc0hne	335	6	the	the	DT
cord-006460-3ayc0hne	335	7	mortality	mortality	NN
cord-006460-3ayc0hne	335	8	from	from	IN
cord-006460-3ayc0hne	335	9	trauma	trauma	NN
cord-006460-3ayc0hne	335	10	decreased	decrease	VBD
cord-006460-3ayc0hne	335	11	,	,	,
cord-006460-3ayc0hne	335	12	but	but	CC
cord-006460-3ayc0hne	335	13	the	the	DT
cord-006460-3ayc0hne	335	14	mortality	mortality	NN
cord-006460-3ayc0hne	335	15	from	from	IN
cord-006460-3ayc0hne	335	16	MOF	MOF	NNP
cord-006460-3ayc0hne	335	17	increased	increase	VBD
cord-006460-3ayc0hne	335	18	.	.	.
cord-006460-3ayc0hne	336	1	Christou	Christou	NNP
cord-006460-3ayc0hne	336	2	et	et	NNP
cord-006460-3ayc0hne	336	3	al	al	NNP
cord-006460-3ayc0hne	336	4	.	.	.
cord-006460-3ayc0hne	337	1	[	[	-LRB-
cord-006460-3ayc0hne	337	2	101	101	CD
cord-006460-3ayc0hne	337	3	]	]	-RRB-
cord-006460-3ayc0hne	337	4	found	find	VBD
cord-006460-3ayc0hne	337	5	that	that	IN
cord-006460-3ayc0hne	337	6	overall	overall	JJ
cord-006460-3ayc0hne	337	7	surgical	surgical	JJ
cord-006460-3ayc0hne	337	8	mortality	mortality	NN
cord-006460-3ayc0hne	337	9	decreased	decrease	VBD
cord-006460-3ayc0hne	337	10	,	,	,
cord-006460-3ayc0hne	337	11	but	but	CC
cord-006460-3ayc0hne	337	12	ICU	ICU	NNP
cord-006460-3ayc0hne	337	13	mortality	mortality	NN
cord-006460-3ayc0hne	337	14	did	do	VBD
cord-006460-3ayc0hne	337	15	not	not	RB
cord-006460-3ayc0hne	337	16	change	change	VB
cord-006460-3ayc0hne	337	17	.	.	.
cord-006460-3ayc0hne	338	1	I	-PRON-	PRP
cord-006460-3ayc0hne	338	2	found	find	VBD
cord-006460-3ayc0hne	338	3	that	that	IN
cord-006460-3ayc0hne	338	4	,	,	,
cord-006460-3ayc0hne	338	5	in	in	IN
cord-006460-3ayc0hne	338	6	cardiac	cardiac	JJ
cord-006460-3ayc0hne	338	7	surgery	surgery	NN
cord-006460-3ayc0hne	338	8	,	,	,
cord-006460-3ayc0hne	338	9	the	the	DT
cord-006460-3ayc0hne	338	10	overall	overall	JJ
cord-006460-3ayc0hne	338	11	incidence	incidence	NN
cord-006460-3ayc0hne	338	12	of	of	IN
cord-006460-3ayc0hne	338	13	MOF	MOF	NNP
cord-006460-3ayc0hne	338	14	was	be	VBD
cord-006460-3ayc0hne	338	15	unchanged	unchanged	JJ
cord-006460-3ayc0hne	338	16	,	,	,
cord-006460-3ayc0hne	338	17	but	but	CC
cord-006460-3ayc0hne	338	18	more	more	JJR
cord-006460-3ayc0hne	338	19	re	re	NNS
cord-006460-3ayc0hne	338	20	-	-	NNS
cord-006460-3ayc0hne	338	21	operations	operation	NNS
cord-006460-3ayc0hne	338	22	were	be	VBD
cord-006460-3ayc0hne	338	23	performed	perform	VBN
cord-006460-3ayc0hne	338	24	recently	recently	RB
cord-006460-3ayc0hne	338	25	where	where	WRB
cord-006460-3ayc0hne	338	26	the	the	DT
cord-006460-3ayc0hne	338	27	incidence	incidence	NN
cord-006460-3ayc0hne	338	28	of	of	IN
cord-006460-3ayc0hne	338	29	MOF	MOF	NNP
cord-006460-3ayc0hne	338	30	was	be	VBD
cord-006460-3ayc0hne	338	31	higher	high	JJR
cord-006460-3ayc0hne	338	32	.	.	.
cord-006460-3ayc0hne	339	1	O'Keefe	O'Keefe	NNP
cord-006460-3ayc0hne	339	2	and	and	CC
cord-006460-3ayc0hne	339	3	Maier	Maier	NNP
cord-006460-3ayc0hne	339	4	[	[	-LRB-
cord-006460-3ayc0hne	339	5	103	103	CD
cord-006460-3ayc0hne	339	6	]	]	-RRB-
cord-006460-3ayc0hne	339	7	concluded	conclude	VBD
cord-006460-3ayc0hne	339	8	that	that	IN
cord-006460-3ayc0hne	339	9	there	there	EX
cord-006460-3ayc0hne	339	10	are	be	VBP
cord-006460-3ayc0hne	339	11	documented	document	VBN
cord-006460-3ayc0hne	339	12	improvements	improvement	NNS
cord-006460-3ayc0hne	339	13	in	in	IN
cord-006460-3ayc0hne	339	14	the	the	DT
cord-006460-3ayc0hne	339	15	treatment	treatment	NN
cord-006460-3ayc0hne	339	16	of	of	IN
cord-006460-3ayc0hne	339	17	septic	septic	JJ
cord-006460-3ayc0hne	339	18	shock	shock	NN
cord-006460-3ayc0hne	339	19	,	,	,
cord-006460-3ayc0hne	339	20	trauma	trauma	NN
cord-006460-3ayc0hne	339	21	,	,	,
cord-006460-3ayc0hne	339	22	ARDS	ARDS	NNP
cord-006460-3ayc0hne	339	23	,	,	,
cord-006460-3ayc0hne	339	24	and	and	CC
cord-006460-3ayc0hne	339	25	that	that	IN
cord-006460-3ayc0hne	339	26	these	these	DT
cord-006460-3ayc0hne	339	27	are	be	VBP
cord-006460-3ayc0hne	339	28	"	"	``
cord-006460-3ayc0hne	339	29	due	due	JJ
cord-006460-3ayc0hne	339	30	to	to	IN
cord-006460-3ayc0hne	339	31	overall	overall	JJ
cord-006460-3ayc0hne	339	32	and	and	CC
cord-006460-3ayc0hne	339	33	cumulative	cumulative	JJ
cord-006460-3ayc0hne	339	34	improvements	improvement	NNS
cord-006460-3ayc0hne	339	35	in	in	IN
cord-006460-3ayc0hne	339	36	care	care	NN
cord-006460-3ayc0hne	339	37	in	in	IN
cord-006460-3ayc0hne	339	38	the	the	DT
cord-006460-3ayc0hne	339	39	ICU	ICU	NNP
cord-006460-3ayc0hne	339	40	rather	rather	RB
cord-006460-3ayc0hne	339	41	than	than	IN
cord-006460-3ayc0hne	339	42	to	to	IN
cord-006460-3ayc0hne	339	43	any	any	DT
cord-006460-3ayc0hne	339	44	isolated	isolate	VBN
cord-006460-3ayc0hne	339	45	specific	specific	JJ
cord-006460-3ayc0hne	339	46	intervention	intervention	NN
cord-006460-3ayc0hne	339	47	.	.	.
cord-006460-3ayc0hne	340	1	"	"	``
cord-006460-3ayc0hne	340	2	They	-PRON-	PRP
cord-006460-3ayc0hne	340	3	predicted	predict	VBD
cord-006460-3ayc0hne	340	4	,	,	,
cord-006460-3ayc0hne	340	5	"	"	``
cord-006460-3ayc0hne	340	6	as	as	IN
cord-006460-3ayc0hne	340	7	survival	survival	NN
cord-006460-3ayc0hne	340	8	rates	rate	NNS
cord-006460-3ayc0hne	340	9	improve	improve	VBP
cord-006460-3ayc0hne	340	10	,	,	,
cord-006460-3ayc0hne	340	11	the	the	DT
cord-006460-3ayc0hne	340	12	ability	ability	NN
cord-006460-3ayc0hne	340	13	to	to	TO
cord-006460-3ayc0hne	340	14	test	test	VB
cord-006460-3ayc0hne	340	15	specific	specific	JJ
cord-006460-3ayc0hne	340	16	interventions	intervention	NNS
cord-006460-3ayc0hne	340	17	and	and	CC
cord-006460-3ayc0hne	340	18	document	document	NN
cord-006460-3ayc0hne	340	19	relevant	relevant	JJ
cord-006460-3ayc0hne	340	20	improvements	improvement	NNS
cord-006460-3ayc0hne	340	21	will	will	MD
cord-006460-3ayc0hne	340	22	become	become	VB
cord-006460-3ayc0hne	340	23	more	more	RBR
cord-006460-3ayc0hne	340	24	difficult	difficult	JJ
cord-006460-3ayc0hne	340	25	.	.	.
cord-006460-3ayc0hne	340	26	"	"	''
cord-006460-3ayc0hne	341	1	The	the	DT
cord-006460-3ayc0hne	341	2	promissory	promissory	JJ
cord-006460-3ayc0hne	341	3	note	note	NN
cord-006460-3ayc0hne	341	4	in	in	IN
cord-006460-3ayc0hne	341	5	scientific	scientific	JJ
cord-006460-3ayc0hne	341	6	research	research	NN
cord-006460-3ayc0hne	341	7	I	-PRON-	PRP
cord-006460-3ayc0hne	341	8	have	have	VBP
cord-006460-3ayc0hne	341	9	described	describe	VBN
cord-006460-3ayc0hne	341	10	the	the	DT
cord-006460-3ayc0hne	341	11	results	result	NNS
cord-006460-3ayc0hne	341	12	of	of	IN
cord-006460-3ayc0hne	341	13	wonderful	wonderful	JJ
cord-006460-3ayc0hne	341	14	studies	study	NNS
cord-006460-3ayc0hne	341	15	of	of	IN
cord-006460-3ayc0hne	341	16	science	science	NN
cord-006460-3ayc0hne	341	17	and	and	CC
cord-006460-3ayc0hne	341	18	injury	injury	NN
cord-006460-3ayc0hne	341	19	and	and	CC
cord-006460-3ayc0hne	341	20	how	how	WRB
cord-006460-3ayc0hne	341	21	some	some	DT
cord-006460-3ayc0hne	341	22	investigators	investigator	NNS
cord-006460-3ayc0hne	341	23	concluded	conclude	VBD
cord-006460-3ayc0hne	341	24	,	,	,
cord-006460-3ayc0hne	341	25	by	by	IN
cord-006460-3ayc0hne	341	26	predicting	predict	VBG
cord-006460-3ayc0hne	341	27	usefulness	usefulness	NN
cord-006460-3ayc0hne	341	28	in	in	IN
cord-006460-3ayc0hne	341	29	patient	patient	JJ
cord-006460-3ayc0hne	341	30	care	care	NN
cord-006460-3ayc0hne	341	31	,	,	,
cord-006460-3ayc0hne	341	32	beyond	beyond	IN
cord-006460-3ayc0hne	341	33	what	what	WP
cord-006460-3ayc0hne	341	34	their	-PRON-	PRP$
cord-006460-3ayc0hne	341	35	studies	study	NNS
cord-006460-3ayc0hne	341	36	allow	allow	VBP
cord-006460-3ayc0hne	341	37	[	[	-LRB-
cord-006460-3ayc0hne	341	38	104	104	CD
cord-006460-3ayc0hne	341	39	]	]	-RRB-
cord-006460-3ayc0hne	341	40	.	.	.
cord-006460-3ayc0hne	342	1	This	this	DT
cord-006460-3ayc0hne	342	2	phenomenon	phenomenon	NN
cord-006460-3ayc0hne	342	3	continues	continue	VBZ
cord-006460-3ayc0hne	342	4	and	and	CC
cord-006460-3ayc0hne	342	5	is	be	VBZ
cord-006460-3ayc0hne	342	6	unfortunate	unfortunate	JJ
cord-006460-3ayc0hne	342	7	.	.	.
cord-006460-3ayc0hne	343	1	Extending	extend	VBG
cord-006460-3ayc0hne	343	2	the	the	DT
cord-006460-3ayc0hne	343	3	results	result	NNS
cord-006460-3ayc0hne	343	4	beyond	beyond	IN
cord-006460-3ayc0hne	343	5	what	what	WP
cord-006460-3ayc0hne	343	6	the	the	DT
cord-006460-3ayc0hne	343	7	study	study	NN
cord-006460-3ayc0hne	343	8	actually	actually	RB
cord-006460-3ayc0hne	343	9	shows	show	VBZ
cord-006460-3ayc0hne	343	10	is	be	VBZ
cord-006460-3ayc0hne	343	11	a	a	DT
cord-006460-3ayc0hne	343	12	form	form	NN
cord-006460-3ayc0hne	343	13	of	of	IN
cord-006460-3ayc0hne	343	14	"	"	``
cord-006460-3ayc0hne	343	15	hype	hype	NN
cord-006460-3ayc0hne	343	16	"	"	''
cord-006460-3ayc0hne	343	17	.	.	.
cord-006460-3ayc0hne	344	1	For	for	IN
cord-006460-3ayc0hne	344	2	example	example	NN
cord-006460-3ayc0hne	344	3	,	,	,
cord-006460-3ayc0hne	344	4	an	an	DT
cord-006460-3ayc0hne	344	5	author	author	NN
cord-006460-3ayc0hne	344	6	may	may	MD
cord-006460-3ayc0hne	344	7	state	state	VB
cord-006460-3ayc0hne	344	8	that	that	IN
cord-006460-3ayc0hne	344	9	these	these	DT
cord-006460-3ayc0hne	344	10	biologic	biologic	JJ
cord-006460-3ayc0hne	344	11	effects	effect	NNS
cord-006460-3ayc0hne	344	12	suggest	suggest	VBP
cord-006460-3ayc0hne	344	13	a	a	DT
cord-006460-3ayc0hne	344	14	promising	promising	JJ
cord-006460-3ayc0hne	344	15	candidate	candidate	NN
cord-006460-3ayc0hne	344	16	for	for	IN
cord-006460-3ayc0hne	344	17	the	the	DT
cord-006460-3ayc0hne	344	18	treatment	treatment	NN
cord-006460-3ayc0hne	344	19	of	of	IN
cord-006460-3ayc0hne	344	20	sepsis	sepsis	NN
cord-006460-3ayc0hne	344	21	in	in	IN
cord-006460-3ayc0hne	344	22	humans	human	NNS
cord-006460-3ayc0hne	344	23	from	from	IN
cord-006460-3ayc0hne	344	24	a	a	DT
cord-006460-3ayc0hne	344	25	study	study	NN
cord-006460-3ayc0hne	344	26	based	base	VBN
cord-006460-3ayc0hne	344	27	on	on	IN
cord-006460-3ayc0hne	344	28	30	30	CD
cord-006460-3ayc0hne	344	29	rats	rat	NNS
cord-006460-3ayc0hne	344	30	.	.	.
cord-006460-3ayc0hne	345	1	Recent	recent	JJ
cord-006460-3ayc0hne	345	2	examples	example	NNS
cord-006460-3ayc0hne	345	3	of	of	IN
cord-006460-3ayc0hne	345	4	this	this	DT
cord-006460-3ayc0hne	345	5	include	include	VBP
cord-006460-3ayc0hne	345	6	a	a	DT
cord-006460-3ayc0hne	345	7	paper	paper	NN
cord-006460-3ayc0hne	345	8	by	by	IN
cord-006460-3ayc0hne	345	9	Forceville	Forceville	NNP
cord-006460-3ayc0hne	345	10	et	et	NNP
cord-006460-3ayc0hne	345	11	al	al	NNP
cord-006460-3ayc0hne	345	12	.	.	.
cord-006460-3ayc0hne	346	1	[	[	-LRB-
cord-006460-3ayc0hne	346	2	105	105	CD
cord-006460-3ayc0hne	346	3	]	]	-RRB-
cord-006460-3ayc0hne	346	4	,	,	,
cord-006460-3ayc0hne	346	5	from	from	IN
cord-006460-3ayc0hne	346	6	Paris	Paris	NNP
cord-006460-3ayc0hne	346	7	,	,	,
cord-006460-3ayc0hne	346	8	where	where	WRB
cord-006460-3ayc0hne	346	9	it	-PRON-	PRP
cord-006460-3ayc0hne	346	10	was	be	VBD
cord-006460-3ayc0hne	346	11	stated	state	VBN
cord-006460-3ayc0hne	346	12	,	,	,
cord-006460-3ayc0hne	346	13	"	"	``
cord-006460-3ayc0hne	346	14	In	in	IN
cord-006460-3ayc0hne	346	15	severely	severely	RB
cord-006460-3ayc0hne	346	16	ill	ill	JJ
cord-006460-3ayc0hne	346	17	ICU	ICU	NNP
cord-006460-3ayc0hne	346	18	patients	patient	NNS
cord-006460-3ayc0hne	346	19	with	with	IN
cord-006460-3ayc0hne	346	20	SIRS	SIRS	NNP
cord-006460-3ayc0hne	346	21	,	,	,
cord-006460-3ayc0hne	346	22	we	-PRON-	PRP
cord-006460-3ayc0hne	346	23	observed	observe	VBD
cord-006460-3ayc0hne	346	24	an	an	DT
cord-006460-3ayc0hne	346	25	early	early	JJ
cord-006460-3ayc0hne	346	26	40	40	CD
cord-006460-3ayc0hne	346	27	%	%	NN
cord-006460-3ayc0hne	346	28	decrease	decrease	NN
cord-006460-3ayc0hne	346	29	in	in	IN
cord-006460-3ayc0hne	346	30	plasma	plasma	NN
cord-006460-3ayc0hne	346	31	selenium	selenium	NN
cord-006460-3ayc0hne	346	32	.	.	.
cord-006460-3ayc0hne	347	1	"	"	``
cord-006460-3ayc0hne	347	2	They	-PRON-	PRP
cord-006460-3ayc0hne	347	3	then	then	RB
cord-006460-3ayc0hne	347	4	went	go	VBD
cord-006460-3ayc0hne	347	5	on	on	RP
cord-006460-3ayc0hne	347	6	to	to	IN
cord-006460-3ayc0hne	347	7	state	state	NN
cord-006460-3ayc0hne	347	8	"	"	''
cord-006460-3ayc0hne	347	9	…	…	NFP
cord-006460-3ayc0hne	347	10	this	this	DT
cord-006460-3ayc0hne	347	11	could	could	MD
cord-006460-3ayc0hne	347	12	explain	explain	VB
cord-006460-3ayc0hne	347	13	the	the	DT
cord-006460-3ayc0hne	347	14	threefold	threefold	JJ
cord-006460-3ayc0hne	347	15	increase	increase	NN
cord-006460-3ayc0hne	347	16	in	in	IN
cord-006460-3ayc0hne	347	17	morbidity	morbidity	NN
cord-006460-3ayc0hne	347	18	and	and	CC
cord-006460-3ayc0hne	347	19	mortality	mortality	NN
cord-006460-3ayc0hne	347	20	rates	rate	NNS
cord-006460-3ayc0hne	347	21	in	in	IN
cord-006460-3ayc0hne	347	22	these	these	DT
cord-006460-3ayc0hne	347	23	patients	patient	NNS
cord-006460-3ayc0hne	347	24	…	…	NFP
cord-006460-3ayc0hne	347	25	"	"	``
cord-006460-3ayc0hne	347	26	This	this	DT
cord-006460-3ayc0hne	347	27	is	be	VBZ
cord-006460-3ayc0hne	347	28	ridiculous	ridiculous	JJ
cord-006460-3ayc0hne	347	29	of	of	IN
cord-006460-3ayc0hne	347	30	course	course	NN
cord-006460-3ayc0hne	347	31	.	.	.
cord-006460-3ayc0hne	348	1	Wong	Wong	NNP
cord-006460-3ayc0hne	348	2	[	[	-LRB-
cord-006460-3ayc0hne	348	3	106	106	CD
cord-006460-3ayc0hne	348	4	]	]	-RRB-
cord-006460-3ayc0hne	348	5	stated	state	VBD
cord-006460-3ayc0hne	348	6	that	that	IN
cord-006460-3ayc0hne	348	7	,	,	,
cord-006460-3ayc0hne	348	8	"	"	``
cord-006460-3ayc0hne	348	9	In	in	IN
cord-006460-3ayc0hne	348	10	molecular	molecular	JJ
cord-006460-3ayc0hne	348	11	terms	term	NNS
cord-006460-3ayc0hne	348	12	,	,	,
cord-006460-3ayc0hne	348	13	MODS	mod	NNS
cord-006460-3ayc0hne	348	14	may	may	MD
cord-006460-3ayc0hne	348	15	occur	occur	VB
cord-006460-3ayc0hne	348	16	when	when	WRB
cord-006460-3ayc0hne	348	17	endothelial	endothelial	JJ
cord-006460-3ayc0hne	348	18	cells	cell	NNS
cord-006460-3ayc0hne	348	19	undergo	undergo	VBP
cord-006460-3ayc0hne	348	20	disparate	disparate	JJ
cord-006460-3ayc0hne	348	21	patterns	pattern	NNS
cord-006460-3ayc0hne	348	22	of	of	IN
cord-006460-3ayc0hne	348	23	gene	gene	NN
cord-006460-3ayc0hne	348	24	expression	expression	NN
cord-006460-3ayc0hne	348	25	either	either	CC
cord-006460-3ayc0hne	348	26	simultaneously	simultaneously	RB
cord-006460-3ayc0hne	348	27	or	or	CC
cord-006460-3ayc0hne	348	28	consecutively	consecutively	RB
cord-006460-3ayc0hne	348	29	.	.	.
cord-006460-3ayc0hne	349	1	"	"	``
cord-006460-3ayc0hne	349	2	That	that	DT
cord-006460-3ayc0hne	349	3	does	do	VBZ
cord-006460-3ayc0hne	349	4	not	not	RB
cord-006460-3ayc0hne	349	5	help	help	VB
cord-006460-3ayc0hne	349	6	me	-PRON-	PRP
cord-006460-3ayc0hne	349	7	understand	understand	VB
cord-006460-3ayc0hne	349	8	MODS	MODS	NNP
cord-006460-3ayc0hne	349	9	.	.	.
cord-006460-3ayc0hne	350	1	In	in	IN
cord-006460-3ayc0hne	350	2	1960	1960	CD
cord-006460-3ayc0hne	350	3	,	,	,
cord-006460-3ayc0hne	350	4	I	-PRON-	PRP
cord-006460-3ayc0hne	350	5	sat	sit	VBD
cord-006460-3ayc0hne	350	6	at	at	IN
cord-006460-3ayc0hne	350	7	a	a	DT
cord-006460-3ayc0hne	350	8	dinner	dinner	NN
cord-006460-3ayc0hne	350	9	of	of	IN
cord-006460-3ayc0hne	350	10	the	the	DT
cord-006460-3ayc0hne	350	11	American	American	NNP
cord-006460-3ayc0hne	350	12	Heart	Heart	NNP
cord-006460-3ayc0hne	350	13	Association	Association	NNP
cord-006460-3ayc0hne	350	14	with	with	IN
cord-006460-3ayc0hne	350	15	the	the	DT
cord-006460-3ayc0hne	350	16	great	great	JJ
cord-006460-3ayc0hne	350	17	pioneer	pioneer	NN
cord-006460-3ayc0hne	350	18	Wilhelm	Wilhelm	NNP
cord-006460-3ayc0hne	350	19	Kolff	Kolff	NNP
cord-006460-3ayc0hne	350	20	.	.	.
cord-006460-3ayc0hne	351	1	Kolff	Kolff	NNP
cord-006460-3ayc0hne	351	2	was	be	VBD
cord-006460-3ayc0hne	351	3	the	the	DT
cord-006460-3ayc0hne	351	4	developer	developer	NN
cord-006460-3ayc0hne	351	5	of	of	IN
cord-006460-3ayc0hne	351	6	the	the	DT
cord-006460-3ayc0hne	351	7	artificial	artificial	JJ
cord-006460-3ayc0hne	351	8	kidney	kidney	NN
cord-006460-3ayc0hne	351	9	,	,	,
cord-006460-3ayc0hne	351	10	an	an	DT
cord-006460-3ayc0hne	351	11	immense	immense	JJ
cord-006460-3ayc0hne	351	12	contribution	contribution	NN
cord-006460-3ayc0hne	351	13	from	from	IN
cord-006460-3ayc0hne	351	14	a	a	DT
cord-006460-3ayc0hne	351	15	man	man	NN
cord-006460-3ayc0hne	351	16	who	who	WP
cord-006460-3ayc0hne	351	17	dedicated	dedicate	VBD
cord-006460-3ayc0hne	351	18	his	-PRON-	PRP$
cord-006460-3ayc0hne	351	19	life	life	NN
cord-006460-3ayc0hne	351	20	to	to	IN
cord-006460-3ayc0hne	351	21	this	this	DT
cord-006460-3ayc0hne	351	22	concept	concept	NN
cord-006460-3ayc0hne	351	23	and	and	CC
cord-006460-3ayc0hne	351	24	the	the	DT
cord-006460-3ayc0hne	351	25	science	science	NN
cord-006460-3ayc0hne	351	26	behind	behind	IN
cord-006460-3ayc0hne	351	27	it	-PRON-	PRP
cord-006460-3ayc0hne	351	28	.	.	.
cord-006460-3ayc0hne	352	1	At	at	IN
cord-006460-3ayc0hne	352	2	this	this	DT
cord-006460-3ayc0hne	352	3	dinner	dinner	NN
cord-006460-3ayc0hne	352	4	,	,	,
cord-006460-3ayc0hne	352	5	Kolff	Kolff	NNP
cord-006460-3ayc0hne	352	6	talked	talk	VBD
cord-006460-3ayc0hne	352	7	about	about	IN
cord-006460-3ayc0hne	352	8	how	how	WRB
cord-006460-3ayc0hne	352	9	science	science	NN
cord-006460-3ayc0hne	352	10	and	and	CC
cord-006460-3ayc0hne	352	11	technology	technology	NN
cord-006460-3ayc0hne	352	12	would	would	MD
cord-006460-3ayc0hne	352	13	advance	advance	VB
cord-006460-3ayc0hne	352	14	.	.	.
cord-006460-3ayc0hne	353	1	He	-PRON-	PRP
cord-006460-3ayc0hne	353	2	stated	state	VBD
cord-006460-3ayc0hne	353	3	that	that	IN
cord-006460-3ayc0hne	353	4	,	,	,
cord-006460-3ayc0hne	353	5	"	"	``
cord-006460-3ayc0hne	353	6	Advances	advance	NNS
cord-006460-3ayc0hne	353	7	in	in	IN
cord-006460-3ayc0hne	353	8	science	science	NN
cord-006460-3ayc0hne	353	9	and	and	CC
cord-006460-3ayc0hne	353	10	technology	technology	NN
cord-006460-3ayc0hne	353	11	will	will	MD
cord-006460-3ayc0hne	353	12	easily	easily	RB
cord-006460-3ayc0hne	353	13	be	be	VB
cord-006460-3ayc0hne	353	14	able	able	JJ
cord-006460-3ayc0hne	353	15	to	to	TO
cord-006460-3ayc0hne	353	16	develop	develop	VB
cord-006460-3ayc0hne	353	17	a	a	DT
cord-006460-3ayc0hne	353	18	satisfactory	satisfactory	JJ
cord-006460-3ayc0hne	353	19	long	long	JJ
cord-006460-3ayc0hne	353	20	-	-	HYPH
cord-006460-3ayc0hne	353	21	term	term	NN
cord-006460-3ayc0hne	353	22	implantable	implantable	JJ
cord-006460-3ayc0hne	353	23	artificial	artificial	JJ
cord-006460-3ayc0hne	353	24	heart	heart	NN
cord-006460-3ayc0hne	353	25	.	.	.
cord-006460-3ayc0hne	353	26	"	"	''
cord-006460-3ayc0hne	354	1	He	-PRON-	PRP
cord-006460-3ayc0hne	354	2	said	say	VBD
cord-006460-3ayc0hne	354	3	that	that	IN
cord-006460-3ayc0hne	354	4	it	-PRON-	PRP
cord-006460-3ayc0hne	354	5	would	would	MD
cord-006460-3ayc0hne	354	6	be	be	VB
cord-006460-3ayc0hne	354	7	just	just	RB
cord-006460-3ayc0hne	354	8	like	like	UH
cord-006460-3ayc0hne	354	9	going	go	VBG
cord-006460-3ayc0hne	354	10	to	to	IN
cord-006460-3ayc0hne	354	11	the	the	DT
cord-006460-3ayc0hne	354	12	moon	moon	NN
cord-006460-3ayc0hne	354	13	,	,	,
cord-006460-3ayc0hne	354	14	a	a	DT
cord-006460-3ayc0hne	354	15	simple	simple	JJ
cord-006460-3ayc0hne	354	16	scientific	scientific	JJ
cord-006460-3ayc0hne	354	17	problem	problem	NN
cord-006460-3ayc0hne	354	18	.	.	.
cord-006460-3ayc0hne	355	1	I	-PRON-	PRP
cord-006460-3ayc0hne	355	2	asked	ask	VBD
cord-006460-3ayc0hne	355	3	him	-PRON-	PRP
cord-006460-3ayc0hne	355	4	whether	whether	IN
cord-006460-3ayc0hne	355	5	he	-PRON-	PRP
cord-006460-3ayc0hne	355	6	thought	think	VBD
cord-006460-3ayc0hne	355	7	there	there	EX
cord-006460-3ayc0hne	355	8	would	would	MD
cord-006460-3ayc0hne	355	9	be	be	VB
cord-006460-3ayc0hne	355	10	any	any	DT
cord-006460-3ayc0hne	355	11	biologic	biologic	JJ
cord-006460-3ayc0hne	355	12	problems	problem	NNS
cord-006460-3ayc0hne	355	13	.	.	.
cord-006460-3ayc0hne	356	1	He	-PRON-	PRP
cord-006460-3ayc0hne	356	2	said	say	VBD
cord-006460-3ayc0hne	356	3	no	no	UH
cord-006460-3ayc0hne	356	4	,	,	,
cord-006460-3ayc0hne	356	5	those	those	DT
cord-006460-3ayc0hne	356	6	were	be	VBD
cord-006460-3ayc0hne	356	7	surmountable	surmountable	JJ
cord-006460-3ayc0hne	356	8	.	.	.
cord-006460-3ayc0hne	357	1	It	-PRON-	PRP
cord-006460-3ayc0hne	357	2	is	be	VBZ
cord-006460-3ayc0hne	357	3	now	now	RB
cord-006460-3ayc0hne	357	4	the	the	DT
cord-006460-3ayc0hne	357	5	year	year	NN
cord-006460-3ayc0hne	357	6	2000	2000	CD
cord-006460-3ayc0hne	357	7	,	,	,
cord-006460-3ayc0hne	357	8	40	40	CD
cord-006460-3ayc0hne	357	9	years	year	NNS
cord-006460-3ayc0hne	357	10	later	later	RB
cord-006460-3ayc0hne	357	11	,	,	,
cord-006460-3ayc0hne	357	12	and	and	CC
cord-006460-3ayc0hne	357	13	there	there	EX
cord-006460-3ayc0hne	357	14	is	be	VBZ
cord-006460-3ayc0hne	357	15	still	still	RB
cord-006460-3ayc0hne	357	16	no	no	DT
cord-006460-3ayc0hne	357	17	satisfactory	satisfactory	JJ
cord-006460-3ayc0hne	357	18	,	,	,
cord-006460-3ayc0hne	357	19	long	long	JJ
cord-006460-3ayc0hne	357	20	-	-	HYPH
cord-006460-3ayc0hne	357	21	term	term	NN
cord-006460-3ayc0hne	357	22	implantable	implantable	JJ
cord-006460-3ayc0hne	357	23	artificial	artificial	JJ
cord-006460-3ayc0hne	357	24	heart	heart	NN
cord-006460-3ayc0hne	357	25	,	,	,
cord-006460-3ayc0hne	357	26	nor	nor	CC
cord-006460-3ayc0hne	357	27	is	be	VBZ
cord-006460-3ayc0hne	357	28	one	one	CD
cord-006460-3ayc0hne	357	29	on	on	IN
cord-006460-3ayc0hne	357	30	the	the	DT
cord-006460-3ayc0hne	357	31	immediate	immediate	JJ
cord-006460-3ayc0hne	357	32	horizon	horizon	NN
cord-006460-3ayc0hne	357	33	.	.	.
cord-006460-3ayc0hne	358	1	Have	have	VBP
cord-006460-3ayc0hne	358	2	there	there	EX
cord-006460-3ayc0hne	358	3	been	be	VBN
cord-006460-3ayc0hne	358	4	any	any	DT
cord-006460-3ayc0hne	358	5	clinical	clinical	JJ
cord-006460-3ayc0hne	358	6	advances	advance	NNS
cord-006460-3ayc0hne	358	7	in	in	IN
cord-006460-3ayc0hne	358	8	the	the	DT
cord-006460-3ayc0hne	358	9	care	care	NN
cord-006460-3ayc0hne	358	10	of	of	IN
cord-006460-3ayc0hne	358	11	patients	patient	NNS
cord-006460-3ayc0hne	358	12	in	in	IN
cord-006460-3ayc0hne	358	13	the	the	DT
cord-006460-3ayc0hne	358	14	past	past	JJ
cord-006460-3ayc0hne	358	15	20	20	CD
cord-006460-3ayc0hne	358	16	years	year	NNS
cord-006460-3ayc0hne	358	17	?	?	.
cord-006460-3ayc0hne	359	1	There	there	EX
cord-006460-3ayc0hne	359	2	have	have	VBP
cord-006460-3ayc0hne	359	3	been	be	VBN
cord-006460-3ayc0hne	359	4	a	a	DT
cord-006460-3ayc0hne	359	5	number	number	NN
cord-006460-3ayc0hne	359	6	of	of	IN
cord-006460-3ayc0hne	359	7	advances	advance	NNS
cord-006460-3ayc0hne	359	8	,	,	,
cord-006460-3ayc0hne	359	9	but	but	CC
cord-006460-3ayc0hne	359	10	they	-PRON-	PRP
cord-006460-3ayc0hne	359	11	are	be	VBP
cord-006460-3ayc0hne	359	12	difficult	difficult	JJ
cord-006460-3ayc0hne	359	13	to	to	TO
cord-006460-3ayc0hne	359	14	document	document	VB
cord-006460-3ayc0hne	359	15	on	on	IN
cord-006460-3ayc0hne	359	16	a	a	DT
cord-006460-3ayc0hne	359	17	patient	patient	NN
cord-006460-3ayc0hne	359	18	-	-	HYPH
cord-006460-3ayc0hne	359	19	by	by	IN
cord-006460-3ayc0hne	359	20	-	-	HYPH
cord-006460-3ayc0hne	359	21	patient	patient	NN
cord-006460-3ayc0hne	359	22	basis	basis	NN
cord-006460-3ayc0hne	359	23	.	.	.
cord-006460-3ayc0hne	360	1	They	-PRON-	PRP
cord-006460-3ayc0hne	360	2	can	can	MD
cord-006460-3ayc0hne	360	3	only	only	RB
cord-006460-3ayc0hne	360	4	be	be	VB
cord-006460-3ayc0hne	360	5	documented	document	VBN
cord-006460-3ayc0hne	360	6	by	by	IN
cord-006460-3ayc0hne	360	7	the	the	DT
cord-006460-3ayc0hne	360	8	types	type	NNS
cord-006460-3ayc0hne	360	9	of	of	IN
cord-006460-3ayc0hne	360	10	experience	experience	NN
cord-006460-3ayc0hne	360	11	that	that	WDT
cord-006460-3ayc0hne	360	12	were	be	VBD
cord-006460-3ayc0hne	360	13	cited	cite	VBN
cord-006460-3ayc0hne	360	14	earlier	early	RBR
cord-006460-3ayc0hne	360	15	in	in	IN
cord-006460-3ayc0hne	360	16	the	the	DT
cord-006460-3ayc0hne	360	17	section	section	NN
cord-006460-3ayc0hne	360	18	entitled	entitle	VBN
cord-006460-3ayc0hne	360	19	"	"	``
cord-006460-3ayc0hne	360	20	Are	be	VBP
cord-006460-3ayc0hne	360	21	we	-PRON-	PRP
cord-006460-3ayc0hne	360	22	improving	improve	VBG
cord-006460-3ayc0hne	360	23	patient	patient	JJ
cord-006460-3ayc0hne	360	24	care	care	NN
cord-006460-3ayc0hne	360	25	and	and	CC
cord-006460-3ayc0hne	360	26	,	,	,
cord-006460-3ayc0hne	360	27	if	if	IN
cord-006460-3ayc0hne	360	28	so	so	RB
cord-006460-3ayc0hne	360	29	,	,	,
cord-006460-3ayc0hne	360	30	how	how	WRB
cord-006460-3ayc0hne	360	31	?	?	.
cord-006460-3ayc0hne	360	32	:	:	:
cord-006460-3ayc0hne	361	1	"	"	``
cord-006460-3ayc0hne	361	2	Is	be	VBZ
cord-006460-3ayc0hne	361	3	multiple	multiple	JJ
cord-006460-3ayc0hne	361	4	organ	organ	NN
cord-006460-3ayc0hne	361	5	failure	failure	NN
cord-006460-3ayc0hne	362	1	disappearing?"Are	disappearing?"are	NN
cord-006460-3ayc0hne	363	1	we	-PRON-	PRP
cord-006460-3ayc0hne	363	2	winning	win	VBG
cord-006460-3ayc0hne	363	3	the	the	DT
cord-006460-3ayc0hne	363	4	battle	battle	NN
cord-006460-3ayc0hne	363	5	?	?	.
cord-006460-3ayc0hne	364	1	One	one	CD
cord-006460-3ayc0hne	364	2	such	such	JJ
cord-006460-3ayc0hne	364	3	advance	advance	NN
cord-006460-3ayc0hne	364	4	is	be	VBZ
cord-006460-3ayc0hne	364	5	better	well	JJR
cord-006460-3ayc0hne	364	6	resuscitation	resuscitation	NN
cord-006460-3ayc0hne	364	7	and	and	CC
cord-006460-3ayc0hne	364	8	initial	initial	JJ
cord-006460-3ayc0hne	364	9	care	care	NN
cord-006460-3ayc0hne	364	10	.	.	.
cord-006460-3ayc0hne	365	1	There	there	EX
cord-006460-3ayc0hne	365	2	certainly	certainly	RB
cord-006460-3ayc0hne	365	3	have	have	VBP
cord-006460-3ayc0hne	365	4	been	be	VBN
cord-006460-3ayc0hne	365	5	improvements	improvement	NNS
cord-006460-3ayc0hne	365	6	in	in	IN
cord-006460-3ayc0hne	365	7	monitoring	monitoring	NN
cord-006460-3ayc0hne	365	8	.	.	.
cord-006460-3ayc0hne	366	1	Early	early	JJ
cord-006460-3ayc0hne	366	2	definitive	definitive	JJ
cord-006460-3ayc0hne	366	3	operations	operation	NNS
cord-006460-3ayc0hne	366	4	for	for	IN
cord-006460-3ayc0hne	366	5	fracture	fracture	NN
cord-006460-3ayc0hne	366	6	immobilization	immobilization	NN
cord-006460-3ayc0hne	366	7	allow	allow	VB
cord-006460-3ayc0hne	366	8	patients	patient	NNS
cord-006460-3ayc0hne	366	9	to	to	TO
cord-006460-3ayc0hne	366	10	move	move	VB
cord-006460-3ayc0hne	366	11	about	about	RB
cord-006460-3ayc0hne	366	12	and	and	CC
cord-006460-3ayc0hne	366	13	decreases	decrease	VBZ
cord-006460-3ayc0hne	366	14	the	the	DT
cord-006460-3ayc0hne	366	15	need	need	NN
cord-006460-3ayc0hne	366	16	for	for	IN
cord-006460-3ayc0hne	366	17	ventilatory	ventilatory	JJ
cord-006460-3ayc0hne	366	18	support	support	NN
cord-006460-3ayc0hne	366	19	and	and	CC
cord-006460-3ayc0hne	366	20	the	the	DT
cord-006460-3ayc0hne	366	21	development	development	NN
cord-006460-3ayc0hne	366	22	of	of	IN
cord-006460-3ayc0hne	366	23	ARDS	ARDS	NNP
cord-006460-3ayc0hne	366	24	[	[	-LRB-
cord-006460-3ayc0hne	366	25	107	107	CD
cord-006460-3ayc0hne	366	26	]	]	-RRB-
cord-006460-3ayc0hne	366	27	.	.	.
cord-006460-3ayc0hne	367	1	Better	well	RBR
cord-006460-3ayc0hne	367	2	circulatory	circulatory	JJ
cord-006460-3ayc0hne	367	3	,	,	,
cord-006460-3ayc0hne	367	4	pulmonary	pulmonary	JJ
cord-006460-3ayc0hne	367	5	and	and	CC
cord-006460-3ayc0hne	367	6	gut	gut	NN
cord-006460-3ayc0hne	367	7	support	support	NN
cord-006460-3ayc0hne	367	8	are	be	VBP
cord-006460-3ayc0hne	367	9	provided	provide	VBN
cord-006460-3ayc0hne	367	10	by	by	IN
cord-006460-3ayc0hne	367	11	various	various	JJ
cord-006460-3ayc0hne	367	12	agents	agent	NNS
cord-006460-3ayc0hne	367	13	,	,	,
cord-006460-3ayc0hne	367	14	ventilator	ventilator	NN
cord-006460-3ayc0hne	367	15	strategies	strategy	NNS
cord-006460-3ayc0hne	367	16	and	and	CC
cord-006460-3ayc0hne	367	17	enteral	enteral	NN
cord-006460-3ayc0hne	367	18	and	and	CC
cord-006460-3ayc0hne	367	19	immune	immune	JJ
cord-006460-3ayc0hne	367	20	nutritional	nutritional	JJ
cord-006460-3ayc0hne	367	21	support	support	NN
cord-006460-3ayc0hne	367	22	[	[	-LRB-
cord-006460-3ayc0hne	367	23	96	96	CD
cord-006460-3ayc0hne	367	24	,	,	,
cord-006460-3ayc0hne	367	25	97	97	CD
cord-006460-3ayc0hne	367	26	]	]	-RRB-
cord-006460-3ayc0hne	367	27	.	.	.
cord-006460-3ayc0hne	368	1	Immune	immune	NN
cord-006460-3ayc0hne	368	2	-	-	HYPH
cord-006460-3ayc0hne	368	3	enhancing	enhance	VBG
cord-006460-3ayc0hne	368	4	diets	diet	NNS
cord-006460-3ayc0hne	368	5	seem	seem	VBP
cord-006460-3ayc0hne	368	6	to	to	TO
cord-006460-3ayc0hne	368	7	make	make	VB
cord-006460-3ayc0hne	368	8	a	a	DT
cord-006460-3ayc0hne	368	9	difference	difference	NN
cord-006460-3ayc0hne	368	10	[	[	-LRB-
cord-006460-3ayc0hne	368	11	108	108	CD
cord-006460-3ayc0hne	368	12	]	]	-RRB-
cord-006460-3ayc0hne	368	13	.	.	.
cord-006460-3ayc0hne	369	1	Hemodiafiltration	Hemodiafiltration	NNP
cord-006460-3ayc0hne	369	2	has	have	VBZ
cord-006460-3ayc0hne	369	3	been	be	VBN
cord-006460-3ayc0hne	369	4	helpful	helpful	JJ
cord-006460-3ayc0hne	369	5	in	in	IN
cord-006460-3ayc0hne	369	6	certain	certain	JJ
cord-006460-3ayc0hne	369	7	circumstances	circumstance	NNS
cord-006460-3ayc0hne	369	8	[	[	-LRB-
cord-006460-3ayc0hne	369	9	109	109	CD
cord-006460-3ayc0hne	369	10	,	,	,
cord-006460-3ayc0hne	369	11	110	110	CD
cord-006460-3ayc0hne	369	12	]	]	-RRB-
cord-006460-3ayc0hne	369	13	.	.	.
cord-006460-3ayc0hne	370	1	In	in	IN
cord-006460-3ayc0hne	370	2	addition	addition	NN
cord-006460-3ayc0hne	370	3	,	,	,
cord-006460-3ayc0hne	370	4	immunomodulation	immunomodulation	NNP
cord-006460-3ayc0hne	370	5	has	have	VBZ
cord-006460-3ayc0hne	370	6	made	make	VBN
cord-006460-3ayc0hne	370	7	a	a	DT
cord-006460-3ayc0hne	370	8	contribution	contribution	NN
cord-006460-3ayc0hne	370	9	.	.	.
cord-006460-3ayc0hne	371	1	Some	some	DT
cord-006460-3ayc0hne	371	2	of	of	IN
cord-006460-3ayc0hne	371	3	the	the	DT
cord-006460-3ayc0hne	371	4	new	new	JJ
cord-006460-3ayc0hne	371	5	therapeutic	therapeutic	JJ
cord-006460-3ayc0hne	371	6	agents	agent	NNS
cord-006460-3ayc0hne	371	7	,	,	,
cord-006460-3ayc0hne	371	8	such	such	JJ
cord-006460-3ayc0hne	371	9	as	as	IN
cord-006460-3ayc0hne	371	10	glucan	glucan	NN
cord-006460-3ayc0hne	371	11	,	,	,
cord-006460-3ayc0hne	371	12	ketoconazole	ketoconazole	NNP
cord-006460-3ayc0hne	371	13	,	,	,
cord-006460-3ayc0hne	371	14	and	and	CC
cord-006460-3ayc0hne	371	15	antithrombin	antithrombin	NN
cord-006460-3ayc0hne	371	16	III	III	NNP
cord-006460-3ayc0hne	371	17	,	,	,
cord-006460-3ayc0hne	371	18	remain	remain	VBP
cord-006460-3ayc0hne	371	19	controversial	controversial	JJ
cord-006460-3ayc0hne	371	20	,	,	,
cord-006460-3ayc0hne	371	21	depending	depend	VBG
cord-006460-3ayc0hne	371	22	on	on	IN
cord-006460-3ayc0hne	371	23	how	how	WRB
cord-006460-3ayc0hne	371	24	they	-PRON-	PRP
cord-006460-3ayc0hne	371	25	are	be	VBP
cord-006460-3ayc0hne	371	26	used	use	VBN
cord-006460-3ayc0hne	371	27	.	.	.
cord-006460-3ayc0hne	372	1	Other	other	JJ
cord-006460-3ayc0hne	372	2	advances	advance	NNS
cord-006460-3ayc0hne	372	3	include	include	VBP
cord-006460-3ayc0hne	372	4	some	some	DT
cord-006460-3ayc0hne	372	5	approximation	approximation	NN
cord-006460-3ayc0hne	372	6	of	of	IN
cord-006460-3ayc0hne	372	7	microcirculatory	microcirculatory	JJ
cord-006460-3ayc0hne	372	8	blood	blood	NN
cord-006460-3ayc0hne	372	9	flow	flow	NN
cord-006460-3ayc0hne	372	10	by	by	IN
cord-006460-3ayc0hne	372	11	measuring	measure	VBG
cord-006460-3ayc0hne	372	12	intercellular	intercellular	JJ
cord-006460-3ayc0hne	372	13	pH	ph	NN
cord-006460-3ayc0hne	372	14	in	in	IN
cord-006460-3ayc0hne	372	15	the	the	DT
cord-006460-3ayc0hne	372	16	stomach	stomach	NN
cord-006460-3ayc0hne	372	17	[	[	-LRB-
cord-006460-3ayc0hne	372	18	111	111	CD
cord-006460-3ayc0hne	372	19	]	]	-RRB-
cord-006460-3ayc0hne	372	20	,	,	,
cord-006460-3ayc0hne	372	21	by	by	IN
cord-006460-3ayc0hne	372	22	minimal	minimal	JJ
cord-006460-3ayc0hne	372	23	surgical	surgical	JJ
cord-006460-3ayc0hne	372	24	procedures	procedure	NNS
cord-006460-3ayc0hne	372	25	,	,	,
cord-006460-3ayc0hne	372	26	the	the	DT
cord-006460-3ayc0hne	372	27	widespread	widespread	JJ
cord-006460-3ayc0hne	372	28	use	use	NN
cord-006460-3ayc0hne	372	29	of	of	IN
cord-006460-3ayc0hne	372	30	epidural	epidural	NN
cord-006460-3ayc0hne	372	31	block	block	NN
cord-006460-3ayc0hne	372	32	and	and	CC
cord-006460-3ayc0hne	372	33	other	other	JJ
cord-006460-3ayc0hne	372	34	adjuncts	adjunct	NNS
cord-006460-3ayc0hne	372	35	.	.	.
cord-006460-3ayc0hne	373	1	There	there	EX
cord-006460-3ayc0hne	373	2	remains	remain	VBZ
cord-006460-3ayc0hne	373	3	the	the	DT
cord-006460-3ayc0hne	373	4	contrast	contrast	NN
cord-006460-3ayc0hne	373	5	between	between	IN
cord-006460-3ayc0hne	373	6	molecular	molecular	JJ
cord-006460-3ayc0hne	373	7	biology	biology	NN
cord-006460-3ayc0hne	373	8	and	and	CC
cord-006460-3ayc0hne	373	9	minimal	minimal	JJ
cord-006460-3ayc0hne	373	10	surgery	surgery	NN
cord-006460-3ayc0hne	373	11	and	and	CC
cord-006460-3ayc0hne	373	12	the	the	DT
cord-006460-3ayc0hne	373	13	disparity	disparity	NN
cord-006460-3ayc0hne	373	14	between	between	IN
cord-006460-3ayc0hne	373	15	them	-PRON-	PRP
cord-006460-3ayc0hne	373	16	[	[	-LRB-
cord-006460-3ayc0hne	373	17	112	112	CD
cord-006460-3ayc0hne	373	18	]	]	-RRB-
cord-006460-3ayc0hne	373	19	.	.	.
cord-006460-3ayc0hne	374	1	Minimal	minimal	JJ
cord-006460-3ayc0hne	374	2	surgery	surgery	NN
cord-006460-3ayc0hne	374	3	has	have	VBZ
cord-006460-3ayc0hne	374	4	certainly	certainly	RB
cord-006460-3ayc0hne	374	5	contributed	contribute	VBN
cord-006460-3ayc0hne	374	6	to	to	TO
cord-006460-3ayc0hne	374	7	better	well	JJR
cord-006460-3ayc0hne	374	8	patient	patient	JJ
cord-006460-3ayc0hne	374	9	care	care	NN
cord-006460-3ayc0hne	374	10	.	.	.
cord-006460-3ayc0hne	375	1	There	there	EX
cord-006460-3ayc0hne	375	2	are	be	VBP
cord-006460-3ayc0hne	375	3	other	other	JJ
cord-006460-3ayc0hne	375	4	procedures	procedure	NNS
cord-006460-3ayc0hne	375	5	on	on	IN
cord-006460-3ayc0hne	375	6	the	the	DT
cord-006460-3ayc0hne	375	7	horizon	horizon	NN
cord-006460-3ayc0hne	375	8	such	such	JJ
cord-006460-3ayc0hne	375	9	as	as	IN
cord-006460-3ayc0hne	375	10	the	the	DT
cord-006460-3ayc0hne	375	11	measurement	measurement	NN
cord-006460-3ayc0hne	375	12	of	of	IN
cord-006460-3ayc0hne	375	13	hemodynamic	hemodynamic	JJ
cord-006460-3ayc0hne	375	14	patterns	pattern	NNS
cord-006460-3ayc0hne	375	15	during	during	IN
cord-006460-3ayc0hne	375	16	high	high	JJ
cord-006460-3ayc0hne	375	17	-	-	HYPH
cord-006460-3ayc0hne	375	18	risk	risk	NN
cord-006460-3ayc0hne	375	19	elective	elective	JJ
cord-006460-3ayc0hne	375	20	operations	operation	NNS
cord-006460-3ayc0hne	375	21	,	,	,
cord-006460-3ayc0hne	375	22	as	as	IN
cord-006460-3ayc0hne	375	23	performed	perform	VBN
cord-006460-3ayc0hne	375	24	by	by	IN
cord-006460-3ayc0hne	375	25	Shoemaker	Shoemaker	NNP
cord-006460-3ayc0hne	375	26	et	et	NNP
cord-006460-3ayc0hne	375	27	al	al	NNP
cord-006460-3ayc0hne	375	28	.	.	.
cord-006460-3ayc0hne	376	1	[	[	-LRB-
cord-006460-3ayc0hne	376	2	113	113	CD
cord-006460-3ayc0hne	376	3	]	]	-RRB-
cord-006460-3ayc0hne	376	4	.	.	.
cord-006460-3ayc0hne	377	1	They	-PRON-	PRP
cord-006460-3ayc0hne	377	2	found	find	VBD
cord-006460-3ayc0hne	377	3	that	that	IN
cord-006460-3ayc0hne	377	4	lethal	lethal	JJ
cord-006460-3ayc0hne	377	5	circulatory	circulatory	JJ
cord-006460-3ayc0hne	377	6	dysfunction	dysfunction	NN
cord-006460-3ayc0hne	377	7	may	may	MD
cord-006460-3ayc0hne	377	8	occur	occur	VB
cord-006460-3ayc0hne	377	9	during	during	IN
cord-006460-3ayc0hne	377	10	the	the	DT
cord-006460-3ayc0hne	377	11	operation	operation	NN
cord-006460-3ayc0hne	377	12	.	.	.
cord-006460-3ayc0hne	378	1	During	during	IN
cord-006460-3ayc0hne	378	2	an	an	DT
cord-006460-3ayc0hne	378	3	operation	operation	NN
cord-006460-3ayc0hne	378	4	,	,	,
cord-006460-3ayc0hne	378	5	non	non	NNS
cord-006460-3ayc0hne	378	6	-	-	NNS
cord-006460-3ayc0hne	378	7	survivors	survivor	NNS
cord-006460-3ayc0hne	378	8	were	be	VBD
cord-006460-3ayc0hne	378	9	found	find	VBN
cord-006460-3ayc0hne	378	10	to	to	TO
cord-006460-3ayc0hne	378	11	have	have	VB
cord-006460-3ayc0hne	378	12	a	a	DT
cord-006460-3ayc0hne	378	13	decreasing	decrease	VBG
cord-006460-3ayc0hne	378	14	cardiac	cardiac	JJ
cord-006460-3ayc0hne	378	15	index	index	NN
cord-006460-3ayc0hne	378	16	and	and	CC
cord-006460-3ayc0hne	378	17	stroke	stroke	NN
cord-006460-3ayc0hne	378	18	index	index	NN
cord-006460-3ayc0hne	378	19	and	and	CC
cord-006460-3ayc0hne	378	20	stroke	stroke	NN
cord-006460-3ayc0hne	378	21	work	work	NN
cord-006460-3ayc0hne	378	22	,	,	,
cord-006460-3ayc0hne	378	23	a	a	DT
cord-006460-3ayc0hne	378	24	decrease	decrease	NN
cord-006460-3ayc0hne	378	25	in	in	IN
cord-006460-3ayc0hne	378	26	oxygen	oxygen	NN
cord-006460-3ayc0hne	378	27	delivery	delivery	NN
cord-006460-3ayc0hne	378	28	,	,	,
cord-006460-3ayc0hne	378	29	and	and	CC
cord-006460-3ayc0hne	378	30	a	a	DT
cord-006460-3ayc0hne	378	31	decrease	decrease	NN
cord-006460-3ayc0hne	378	32	in	in	IN
cord-006460-3ayc0hne	378	33	oxygen	oxygen	NN
cord-006460-3ayc0hne	378	34	consumption	consumption	NN
cord-006460-3ayc0hne	378	35	[	[	-LRB-
cord-006460-3ayc0hne	378	36	114	114	CD
cord-006460-3ayc0hne	378	37	]	]	-RRB-
cord-006460-3ayc0hne	378	38	.	.	.
cord-006460-3ayc0hne	379	1	Identifying	identify	VBG
cord-006460-3ayc0hne	379	2	these	these	DT
cord-006460-3ayc0hne	379	3	factors	factor	NNS
cord-006460-3ayc0hne	379	4	during	during	IN
cord-006460-3ayc0hne	379	5	surgery	surgery	NN
cord-006460-3ayc0hne	379	6	may	may	MD
cord-006460-3ayc0hne	379	7	allow	allow	VB
cord-006460-3ayc0hne	379	8	immediate	immediate	JJ
cord-006460-3ayc0hne	379	9	corrective	corrective	JJ
cord-006460-3ayc0hne	379	10	measures	measure	NNS
cord-006460-3ayc0hne	379	11	.	.	.
cord-006460-3ayc0hne	380	1	We	-PRON-	PRP
cord-006460-3ayc0hne	380	2	found	find	VBD
cord-006460-3ayc0hne	380	3	,	,	,
cord-006460-3ayc0hne	380	4	for	for	IN
cord-006460-3ayc0hne	380	5	example	example	NN
cord-006460-3ayc0hne	380	6	,	,	,
cord-006460-3ayc0hne	380	7	that	that	IN
cord-006460-3ayc0hne	380	8	using	use	VBG
cord-006460-3ayc0hne	380	9	oxygen	oxygen	NN
cord-006460-3ayc0hne	380	10	consumption	consumption	NN
cord-006460-3ayc0hne	380	11	and	and	CC
cord-006460-3ayc0hne	380	12	delivery	delivery	NN
cord-006460-3ayc0hne	380	13	as	as	IN
cord-006460-3ayc0hne	380	14	endpoints	endpoint	NNS
cord-006460-3ayc0hne	380	15	for	for	IN
cord-006460-3ayc0hne	380	16	resuscitation	resuscitation	NN
cord-006460-3ayc0hne	380	17	in	in	IN
cord-006460-3ayc0hne	380	18	critically	critically	RB
cord-006460-3ayc0hne	380	19	ill	ill	JJ
cord-006460-3ayc0hne	380	20	patients	patient	NNS
cord-006460-3ayc0hne	380	21	is	be	VBZ
cord-006460-3ayc0hne	380	22	not	not	RB
cord-006460-3ayc0hne	380	23	particularly	particularly	RB
cord-006460-3ayc0hne	380	24	helpful	helpful	JJ
cord-006460-3ayc0hne	380	25	.	.	.
cord-006460-3ayc0hne	381	1	Oxygen	oxygen	NN
cord-006460-3ayc0hne	381	2	parameters	parameter	NNS
cord-006460-3ayc0hne	381	3	are	be	VBP
cord-006460-3ayc0hne	381	4	more	more	RBR
cord-006460-3ayc0hne	381	5	useful	useful	JJ
cord-006460-3ayc0hne	381	6	as	as	IN
cord-006460-3ayc0hne	381	7	predictors	predictor	NNS
cord-006460-3ayc0hne	381	8	of	of	IN
cord-006460-3ayc0hne	381	9	outcome	outcome	NN
cord-006460-3ayc0hne	381	10	than	than	IN
cord-006460-3ayc0hne	381	11	as	as	IN
cord-006460-3ayc0hne	381	12	endpoints	endpoint	NNS
cord-006460-3ayc0hne	381	13	for	for	IN
cord-006460-3ayc0hne	381	14	resuscitation	resuscitation	NN
cord-006460-3ayc0hne	381	15	[	[	-LRB-
cord-006460-3ayc0hne	381	16	115	115	CD
cord-006460-3ayc0hne	381	17	]	]	-RRB-
cord-006460-3ayc0hne	381	18	.	.	.
cord-006460-3ayc0hne	382	1	We	-PRON-	PRP
cord-006460-3ayc0hne	382	2	have	have	VBP
cord-006460-3ayc0hne	382	3	known	know	VBN
cord-006460-3ayc0hne	382	4	for	for	IN
cord-006460-3ayc0hne	382	5	many	many	JJ
cord-006460-3ayc0hne	382	6	years	year	NNS
cord-006460-3ayc0hne	382	7	that	that	IN
cord-006460-3ayc0hne	382	8	surgical	surgical	JJ
cord-006460-3ayc0hne	382	9	and	and	CC
cord-006460-3ayc0hne	382	10	injured	injured	JJ
cord-006460-3ayc0hne	382	11	patients	patient	NNS
cord-006460-3ayc0hne	382	12	must	must	MD
cord-006460-3ayc0hne	382	13	increase	increase	VB
cord-006460-3ayc0hne	382	14	oxygen	oxygen	NN
cord-006460-3ayc0hne	382	15	transport	transport	NN
cord-006460-3ayc0hne	382	16	,	,	,
cord-006460-3ayc0hne	382	17	cardiac	cardiac	JJ
cord-006460-3ayc0hne	382	18	index	index	NN
cord-006460-3ayc0hne	382	19	and	and	CC
cord-006460-3ayc0hne	382	20	oxygen	oxygen	NN
cord-006460-3ayc0hne	382	21	consumption	consumption	NN
cord-006460-3ayc0hne	382	22	to	to	TO
cord-006460-3ayc0hne	382	23	survive	survive	VB
cord-006460-3ayc0hne	382	24	.	.	.
cord-006460-3ayc0hne	383	1	Goodwin	Goodwin	NNP
cord-006460-3ayc0hne	383	2	[	[	-LRB-
cord-006460-3ayc0hne	383	3	116	116	CD
cord-006460-3ayc0hne	383	4	]	]	-RRB-
cord-006460-3ayc0hne	383	5	stated	state	VBD
cord-006460-3ayc0hne	383	6	that	that	IN
cord-006460-3ayc0hne	383	7	,	,	,
cord-006460-3ayc0hne	383	8	"	"	``
cord-006460-3ayc0hne	383	9	The	the	DT
cord-006460-3ayc0hne	383	10	great	great	JJ
cord-006460-3ayc0hne	383	11	gift	gift	NN
cord-006460-3ayc0hne	383	12	of	of	IN
cord-006460-3ayc0hne	383	13	chaos	chaos	NN
cord-006460-3ayc0hne	383	14	theory	theory	NN
cord-006460-3ayc0hne	383	15	to	to	IN
cord-006460-3ayc0hne	383	16	the	the	DT
cord-006460-3ayc0hne	383	17	practice	practice	NN
cord-006460-3ayc0hne	383	18	of	of	IN
cord-006460-3ayc0hne	383	19	medicine	medicine	NN
cord-006460-3ayc0hne	383	20	has	have	VBZ
cord-006460-3ayc0hne	383	21	been	be	VBN
cord-006460-3ayc0hne	383	22	the	the	DT
cord-006460-3ayc0hne	383	23	simple	simple	JJ
cord-006460-3ayc0hne	383	24	but	but	CC
cord-006460-3ayc0hne	383	25	profound	profound	JJ
cord-006460-3ayc0hne	383	26	negative	negative	JJ
cord-006460-3ayc0hne	383	27	statement	statement	NN
cord-006460-3ayc0hne	383	28	:	:	:
cord-006460-3ayc0hne	383	29	'	'	``
cord-006460-3ayc0hne	383	30	Traditional	traditional	JJ
cord-006460-3ayc0hne	383	31	science	science	NN
cord-006460-3ayc0hne	383	32	can	can	MD
cord-006460-3ayc0hne	383	33	not	not	RB
cord-006460-3ayc0hne	383	34	predict	predict	VB
cord-006460-3ayc0hne	383	35	complex	complex	JJ
cord-006460-3ayc0hne	383	36	systems	system	NNS
cord-006460-3ayc0hne	383	37	'	'	''
cord-006460-3ayc0hne	383	38	.	.	.
cord-006460-3ayc0hne	384	1	"	"	``
cord-006460-3ayc0hne	384	2	People	People	NNS
cord-006460-3ayc0hne	384	3	(	(	-LRB-
cord-006460-3ayc0hne	384	4	patients	patient	NNS
cord-006460-3ayc0hne	384	5	)	)	-RRB-
cord-006460-3ayc0hne	384	6	are	be	VBP
cord-006460-3ayc0hne	384	7	such	such	JJ
cord-006460-3ayc0hne	384	8	complex	complex	JJ
cord-006460-3ayc0hne	384	9	systems	system	NNS
cord-006460-3ayc0hne	384	10	.	.	.
cord-006460-3ayc0hne	385	1	Another	another	DT
cord-006460-3ayc0hne	385	2	reason	reason	NN
cord-006460-3ayc0hne	385	3	for	for	IN
cord-006460-3ayc0hne	385	4	the	the	DT
cord-006460-3ayc0hne	385	5	discrepancy	discrepancy	NN
cord-006460-3ayc0hne	385	6	between	between	IN
cord-006460-3ayc0hne	385	7	our	-PRON-	PRP$
cord-006460-3ayc0hne	385	8	science	science	NN
cord-006460-3ayc0hne	385	9	and	and	CC
cord-006460-3ayc0hne	385	10	patient	patient	NN
cord-006460-3ayc0hne	385	11	care	care	NN
cord-006460-3ayc0hne	385	12	is	be	VBZ
cord-006460-3ayc0hne	385	13	that	that	IN
cord-006460-3ayc0hne	385	14	much	much	JJ
cord-006460-3ayc0hne	385	15	of	of	IN
cord-006460-3ayc0hne	385	16	science	science	NN
cord-006460-3ayc0hne	385	17	today	today	NN
cord-006460-3ayc0hne	385	18	is	be	VBZ
cord-006460-3ayc0hne	385	19	based	base	VBN
cord-006460-3ayc0hne	385	20	on	on	IN
cord-006460-3ayc0hne	385	21	traditional	traditional	JJ
cord-006460-3ayc0hne	385	22	concepts	concept	NNS
cord-006460-3ayc0hne	385	23	.	.	.
cord-006460-3ayc0hne	386	1	The	the	DT
cord-006460-3ayc0hne	386	2	"	"	``
cord-006460-3ayc0hne	386	3	milieu	milieu	NN
cord-006460-3ayc0hne	386	4	interieur	interieur	NN
cord-006460-3ayc0hne	386	5	"	"	''
cord-006460-3ayc0hne	386	6	of	of	IN
cord-006460-3ayc0hne	386	7	Bernard	Bernard	NNP
cord-006460-3ayc0hne	386	8	[	[	-LRB-
cord-006460-3ayc0hne	386	9	117	117	CD
cord-006460-3ayc0hne	386	10	]	]	-RRB-
cord-006460-3ayc0hne	386	11	is	be	VBZ
cord-006460-3ayc0hne	386	12	important	important	JJ
cord-006460-3ayc0hne	386	13	,	,	,
cord-006460-3ayc0hne	386	14	as	as	IN
cord-006460-3ayc0hne	386	15	is	be	VBZ
cord-006460-3ayc0hne	386	16	the	the	DT
cord-006460-3ayc0hne	386	17	contribution	contribution	NN
cord-006460-3ayc0hne	386	18	to	to	IN
cord-006460-3ayc0hne	386	19	homeostasis	homeostasis	NN
cord-006460-3ayc0hne	386	20	by	by	IN
cord-006460-3ayc0hne	386	21	Cannon	Cannon	NNP
cord-006460-3ayc0hne	386	22	[	[	-LRB-
cord-006460-3ayc0hne	386	23	118	118	CD
cord-006460-3ayc0hne	386	24	]	]	-RRB-
cord-006460-3ayc0hne	386	25	.	.	.
cord-006460-3ayc0hne	387	1	Now	now	RB
cord-006460-3ayc0hne	387	2	there	there	EX
cord-006460-3ayc0hne	387	3	is	be	VBZ
cord-006460-3ayc0hne	387	4	a	a	DT
cord-006460-3ayc0hne	387	5	new	new	JJ
cord-006460-3ayc0hne	387	6	science	science	NN
cord-006460-3ayc0hne	387	7	of	of	IN
cord-006460-3ayc0hne	387	8	non	non	JJ
cord-006460-3ayc0hne	387	9	-	-	JJ
cord-006460-3ayc0hne	387	10	linear	linear	JJ
cord-006460-3ayc0hne	387	11	integration	integration	NN
cord-006460-3ayc0hne	387	12	,	,	,
cord-006460-3ayc0hne	387	13	which	which	WDT
cord-006460-3ayc0hne	387	14	,	,	,
cord-006460-3ayc0hne	387	15	according	accord	VBG
cord-006460-3ayc0hne	387	16	to	to	IN
cord-006460-3ayc0hne	387	17	Schultz	Schultz	NNP
cord-006460-3ayc0hne	387	18	[	[	-LRB-
cord-006460-3ayc0hne	387	19	119	119	CD
cord-006460-3ayc0hne	387	20	]	]	-RRB-
cord-006460-3ayc0hne	387	21	,	,	,
cord-006460-3ayc0hne	387	22	may	may	MD
cord-006460-3ayc0hne	387	23	be	be	VB
cord-006460-3ayc0hne	387	24	another	another	DT
cord-006460-3ayc0hne	387	25	emerging	emerge	VBG
cord-006460-3ayc0hne	387	26	scientific	scientific	JJ
cord-006460-3ayc0hne	387	27	revolution	revolution	NN
cord-006460-3ayc0hne	387	28	.	.	.
cord-006460-3ayc0hne	388	1	He	-PRON-	PRP
cord-006460-3ayc0hne	388	2	stated	state	VBD
cord-006460-3ayc0hne	388	3	that	that	IN
cord-006460-3ayc0hne	388	4	,	,	,
cord-006460-3ayc0hne	388	5	"	"	``
cord-006460-3ayc0hne	388	6	Molecular	molecular	JJ
cord-006460-3ayc0hne	388	7	biology	biology	NN
cord-006460-3ayc0hne	388	8	provides	provide	VBZ
cord-006460-3ayc0hne	388	9	parts	part	NNS
cord-006460-3ayc0hne	388	10	of	of	IN
cord-006460-3ayc0hne	388	11	a	a	DT
cord-006460-3ayc0hne	388	12	puzzle	puzzle	NN
cord-006460-3ayc0hne	388	13	which	which	WDT
cord-006460-3ayc0hne	388	14	are	be	VBP
cord-006460-3ayc0hne	388	15	dynamic	dynamic	JJ
cord-006460-3ayc0hne	388	16	or	or	CC
cord-006460-3ayc0hne	388	17	plastic	plastic	JJ
cord-006460-3ayc0hne	388	18	.	.	.
cord-006460-3ayc0hne	389	1	Putting	put	VBG
cord-006460-3ayc0hne	389	2	them	-PRON-	PRP
cord-006460-3ayc0hne	389	3	together	together	RB
cord-006460-3ayc0hne	389	4	is	be	VBZ
cord-006460-3ayc0hne	389	5	the	the	DT
cord-006460-3ayc0hne	389	6	problem	problem	NN
cord-006460-3ayc0hne	389	7	.	.	.
cord-006460-3ayc0hne	390	1	"	"	``
cord-006460-3ayc0hne	390	2	It	-PRON-	PRP
cord-006460-3ayc0hne	390	3	is	be	VBZ
cord-006460-3ayc0hne	390	4	our	-PRON-	PRP$
cord-006460-3ayc0hne	390	5	job	job	NN
cord-006460-3ayc0hne	390	6	to	to	TO
cord-006460-3ayc0hne	390	7	put	put	VB
cord-006460-3ayc0hne	390	8	them	-PRON-	PRP
cord-006460-3ayc0hne	390	9	together	together	RB
cord-006460-3ayc0hne	390	10	by	by	IN
cord-006460-3ayc0hne	390	11	learning	learn	VBG
cord-006460-3ayc0hne	390	12	the	the	DT
cord-006460-3ayc0hne	390	13	rules	rule	NNS
cord-006460-3ayc0hne	390	14	of	of	IN
cord-006460-3ayc0hne	390	15	association	association	NN
cord-006460-3ayc0hne	390	16	or	or	CC
cord-006460-3ayc0hne	390	17	integration	integration	NN
cord-006460-3ayc0hne	390	18	.	.	.
cord-006460-3ayc0hne	391	1	Schultz	Schultz	NNP
cord-006460-3ayc0hne	391	2	described	describe	VBD
cord-006460-3ayc0hne	391	3	non	non	JJ
cord-006460-3ayc0hne	391	4	-	-	NN
cord-006460-3ayc0hne	391	5	linearity	linearity	NN
cord-006460-3ayc0hne	391	6	as	as	IN
cord-006460-3ayc0hne	391	7	"	"	``
cord-006460-3ayc0hne	391	8	the	the	DT
cord-006460-3ayc0hne	391	9	shape	shape	NN
cord-006460-3ayc0hne	391	10	of	of	IN
cord-006460-3ayc0hne	391	11	the	the	DT
cord-006460-3ayc0hne	391	12	'	'	``
cord-006460-3ayc0hne	391	13	whole	whole	NN
cord-006460-3ayc0hne	391	14	'	'	''
cord-006460-3ayc0hne	391	15	can	can	MD
cord-006460-3ayc0hne	391	16	not	not	RB
cord-006460-3ayc0hne	391	17	be	be	VB
cord-006460-3ayc0hne	391	18	predicted	predict	VBN
cord-006460-3ayc0hne	391	19	by	by	IN
cord-006460-3ayc0hne	391	20	knowing	know	VBG
cord-006460-3ayc0hne	391	21	only	only	RB
cord-006460-3ayc0hne	391	22	the	the	DT
cord-006460-3ayc0hne	391	23	shapes	shape	NNS
cord-006460-3ayc0hne	391	24	of	of	IN
cord-006460-3ayc0hne	391	25	the	the	DT
cord-006460-3ayc0hne	391	26	separated	separated	JJ
cord-006460-3ayc0hne	391	27	parts	part	NNS
cord-006460-3ayc0hne	391	28	.	.	.
cord-006460-3ayc0hne	391	29	"	"	''
cord-006460-3ayc0hne	392	1	Buchman	Buchman	NNP
cord-006460-3ayc0hne	392	2	stated	state	VBD
cord-006460-3ayc0hne	392	3	that	that	IN
cord-006460-3ayc0hne	392	4	"	"	``
cord-006460-3ayc0hne	392	5	if	if	IN
cord-006460-3ayc0hne	392	6	nested	nest	VBN
cord-006460-3ayc0hne	392	7	,	,	,
cord-006460-3ayc0hne	392	8	nonlinear	nonlinear	JJ
cord-006460-3ayc0hne	392	9	models	model	NNS
cord-006460-3ayc0hne	392	10	are	be	VBP
cord-006460-3ayc0hne	392	11	better	well	JJR
cord-006460-3ayc0hne	392	12	representatives	representative	NNS
cord-006460-3ayc0hne	392	13	of	of	IN
cord-006460-3ayc0hne	392	14	human	human	JJ
cord-006460-3ayc0hne	392	15	physiology	physiology	NN
cord-006460-3ayc0hne	392	16	,	,	,
cord-006460-3ayc0hne	392	17	than	than	IN
cord-006460-3ayc0hne	392	18	Cannon	Cannon	NNP
cord-006460-3ayc0hne	392	19	's	's	POS
cord-006460-3ayc0hne	392	20	collection	collection	NN
cord-006460-3ayc0hne	392	21	of	of	IN
cord-006460-3ayc0hne	392	22	negative	negative	JJ
cord-006460-3ayc0hne	392	23	feedback	feedback	NN
cord-006460-3ayc0hne	392	24	servomechanisms	servomechanism	NNS
cord-006460-3ayc0hne	392	25	,	,	,
cord-006460-3ayc0hne	392	26	then	then	RB
cord-006460-3ayc0hne	392	27	therapy	therapy	NN
cord-006460-3ayc0hne	392	28	should	should	MD
cord-006460-3ayc0hne	392	29	be	be	VB
cord-006460-3ayc0hne	392	30	redirected	redirect	VBN
cord-006460-3ayc0hne	392	31	toward	toward	IN
cord-006460-3ayc0hne	392	32	transitions	transition	NNS
cord-006460-3ayc0hne	392	33	to	to	IN
cord-006460-3ayc0hne	392	34	a	a	DT
cord-006460-3ayc0hne	392	35	basal	basal	NN
cord-006460-3ayc0hne	392	36	range	range	NN
cord-006460-3ayc0hne	392	37	-not	-not	:
cord-006460-3ayc0hne	392	38	therapeutically	therapeutically	RB
cord-006460-3ayc0hne	392	39	manipulating	manipulate	VBG
cord-006460-3ayc0hne	392	40	things	thing	NNS
cord-006460-3ayc0hne	392	41	such	such	JJ
cord-006460-3ayc0hne	392	42	as	as	IN
cord-006460-3ayc0hne	392	43	cytokines	cytokine	NNS
cord-006460-3ayc0hne	392	44	or	or	CC
cord-006460-3ayc0hne	392	45	nitric	nitric	NN
cord-006460-3ayc0hne	392	46	oxide	oxide	NN
cord-006460-3ayc0hne	392	47	"	"	''
cord-006460-3ayc0hne	392	48	[	[	-LRB-
cord-006460-3ayc0hne	392	49	120	120	CD
cord-006460-3ayc0hne	392	50	]	]	-RRB-
cord-006460-3ayc0hne	392	51	.	.	.
cord-006460-3ayc0hne	393	1	Focusing	focus	VBG
cord-006460-3ayc0hne	393	2	on	on	IN
cord-006460-3ayc0hne	393	3	the	the	DT
cord-006460-3ayc0hne	393	4	phases	phase	NNS
cord-006460-3ayc0hne	393	5	of	of	IN
cord-006460-3ayc0hne	393	6	inflammation	inflammation	NN
cord-006460-3ayc0hne	393	7	(	(	-LRB-
cord-006460-3ayc0hne	393	8	pro	pro	JJ
cord-006460-3ayc0hne	393	9	-	-	JJ
cord-006460-3ayc0hne	393	10	anti	anti	JJ
cord-006460-3ayc0hne	393	11	,	,	,
cord-006460-3ayc0hne	393	12	etc	etc	FW
cord-006460-3ayc0hne	393	13	.	.	.
cord-006460-3ayc0hne	393	14	)	)	-RRB-
cord-006460-3ayc0hne	393	15	would	would	MD
cord-006460-3ayc0hne	393	16	be	be	VB
cord-006460-3ayc0hne	393	17	Cannon	Cannon	NNP
cord-006460-3ayc0hne	393	18	's	's	POS
cord-006460-3ayc0hne	393	19	approach	approach	NN
cord-006460-3ayc0hne	393	20	.	.	.
cord-006460-3ayc0hne	394	1	Blocking	block	VBG
cord-006460-3ayc0hne	394	2	one	one	CD
cord-006460-3ayc0hne	394	3	mediator	mediator	NN
cord-006460-3ayc0hne	394	4	may	may	MD
cord-006460-3ayc0hne	394	5	change	change	VB
cord-006460-3ayc0hne	394	6	not	not	RB
cord-006460-3ayc0hne	394	7	only	only	RB
cord-006460-3ayc0hne	394	8	the	the	DT
cord-006460-3ayc0hne	394	9	effects	effect	NNS
cord-006460-3ayc0hne	394	10	of	of	IN
cord-006460-3ayc0hne	394	11	that	that	DT
cord-006460-3ayc0hne	394	12	mediator	mediator	NN
cord-006460-3ayc0hne	394	13	,	,	,
cord-006460-3ayc0hne	394	14	but	but	CC
cord-006460-3ayc0hne	394	15	may	may	MD
cord-006460-3ayc0hne	394	16	also	also	RB
cord-006460-3ayc0hne	394	17	disturb	disturb	VB
cord-006460-3ayc0hne	394	18	other	other	JJ
cord-006460-3ayc0hne	394	19	mediators	mediator	NNS
cord-006460-3ayc0hne	394	20	and	and	CC
cord-006460-3ayc0hne	394	21	the	the	DT
cord-006460-3ayc0hne	394	22	entire	entire	JJ
cord-006460-3ayc0hne	394	23	system	system	NN
cord-006460-3ayc0hne	394	24	.	.	.
cord-006460-3ayc0hne	395	1	Sir	Sir	NNP
cord-006460-3ayc0hne	395	2	Karl	Karl	NNP
cord-006460-3ayc0hne	395	3	Popper	Popper	NNP
cord-006460-3ayc0hne	395	4	,	,	,
cord-006460-3ayc0hne	395	5	in	in	IN
cord-006460-3ayc0hne	395	6	his	-PRON-	PRP$
cord-006460-3ayc0hne	395	7	Medawar	Medawar	NNP
cord-006460-3ayc0hne	395	8	Lecture	Lecture	NNP
cord-006460-3ayc0hne	395	9	in	in	IN
cord-006460-3ayc0hne	395	10	1986	1986	CD
cord-006460-3ayc0hne	395	11	to	to	IN
cord-006460-3ayc0hne	395	12	the	the	DT
cord-006460-3ayc0hne	395	13	Royal	Royal	NNP
cord-006460-3ayc0hne	395	14	Society	Society	NNP
cord-006460-3ayc0hne	395	15	in	in	IN
cord-006460-3ayc0hne	395	16	London	London	NNP
cord-006460-3ayc0hne	395	17	,	,	,
cord-006460-3ayc0hne	395	18	stated	state	VBD
cord-006460-3ayc0hne	395	19	that	that	IN
cord-006460-3ayc0hne	395	20	"	"	``
cord-006460-3ayc0hne	395	21	biology	biology	NN
cord-006460-3ayc0hne	395	22	can	can	MD
cord-006460-3ayc0hne	395	23	not	not	RB
cord-006460-3ayc0hne	395	24	be	be	VB
cord-006460-3ayc0hne	395	25	reduced	reduce	VBN
cord-006460-3ayc0hne	395	26	to	to	IN
cord-006460-3ayc0hne	395	27	physics	physics	NN
cord-006460-3ayc0hne	395	28	because	because	IN
cord-006460-3ayc0hne	395	29	biochemistry	biochemistry	NN
cord-006460-3ayc0hne	395	30	can	can	MD
cord-006460-3ayc0hne	395	31	not	not	RB
cord-006460-3ayc0hne	395	32	be	be	VB
cord-006460-3ayc0hne	395	33	reduced	reduce	VBN
cord-006460-3ayc0hne	395	34	to	to	IN
cord-006460-3ayc0hne	395	35	chemistry	chemistry	NN
cord-006460-3ayc0hne	395	36	.	.	.
cord-006460-3ayc0hne	396	1	Reductionism	reductionism	NN
cord-006460-3ayc0hne	396	2	is	be	VBZ
cord-006460-3ayc0hne	396	3	not	not	RB
cord-006460-3ayc0hne	396	4	possible	possible	JJ
cord-006460-3ayc0hne	396	5	in	in	IN
cord-006460-3ayc0hne	396	6	biologic	biologic	JJ
cord-006460-3ayc0hne	396	7	systems	system	NNS
cord-006460-3ayc0hne	396	8	.	.	.
cord-006460-3ayc0hne	397	1	An	an	DT
cord-006460-3ayc0hne	397	2	organism	organism	NN
cord-006460-3ayc0hne	397	3	can	can	MD
cord-006460-3ayc0hne	397	4	not	not	RB
cord-006460-3ayc0hne	397	5	be	be	VB
cord-006460-3ayc0hne	397	6	reduced	reduce	VBN
cord-006460-3ayc0hne	397	7	to	to	IN
cord-006460-3ayc0hne	397	8	a	a	DT
cord-006460-3ayc0hne	397	9	series	series	NN
cord-006460-3ayc0hne	397	10	of	of	IN
cord-006460-3ayc0hne	397	11	systems	system	NNS
cord-006460-3ayc0hne	397	12	"	"	''
cord-006460-3ayc0hne	397	13	[	[	-LRB-
cord-006460-3ayc0hne	397	14	121	121	CD
cord-006460-3ayc0hne	397	15	]	]	-RRB-
cord-006460-3ayc0hne	397	16	.	.	.
cord-006460-3ayc0hne	398	1	As	as	IN
cord-006460-3ayc0hne	398	2	physicians	physician	NNS
cord-006460-3ayc0hne	398	3	,	,	,
cord-006460-3ayc0hne	398	4	we	-PRON-	PRP
cord-006460-3ayc0hne	398	5	were	be	VBD
cord-006460-3ayc0hne	398	6	taught	teach	VBN
cord-006460-3ayc0hne	398	7	that	that	IN
cord-006460-3ayc0hne	398	8	stability	stability	NN
cord-006460-3ayc0hne	398	9	is	be	VBZ
cord-006460-3ayc0hne	398	10	healthy	healthy	JJ
cord-006460-3ayc0hne	398	11	.	.	.
cord-006460-3ayc0hne	399	1	Now	now	RB
cord-006460-3ayc0hne	399	2	we	-PRON-	PRP
cord-006460-3ayc0hne	399	3	are	be	VBP
cord-006460-3ayc0hne	399	4	learning	learn	VBG
cord-006460-3ayc0hne	399	5	that	that	IN
cord-006460-3ayc0hne	399	6	regularity	regularity	NN
cord-006460-3ayc0hne	399	7	and	and	CC
cord-006460-3ayc0hne	399	8	stability	stability	NN
cord-006460-3ayc0hne	399	9	are	be	VBP
cord-006460-3ayc0hne	399	10	more	more	RBR
cord-006460-3ayc0hne	399	11	characteristic	characteristic	JJ
cord-006460-3ayc0hne	399	12	of	of	IN
cord-006460-3ayc0hne	399	13	the	the	DT
cord-006460-3ayc0hne	399	14	beginning	beginning	NN
cord-006460-3ayc0hne	399	15	of	of	IN
cord-006460-3ayc0hne	399	16	disease	disease	NN
cord-006460-3ayc0hne	399	17	.	.	.
cord-006460-3ayc0hne	400	1	For	for	IN
cord-006460-3ayc0hne	400	2	example	example	NN
cord-006460-3ayc0hne	400	3	,	,	,
cord-006460-3ayc0hne	400	4	injection	injection	NN
cord-006460-3ayc0hne	400	5	of	of	IN
cord-006460-3ayc0hne	400	6	endotoxin	endotoxin	NN
cord-006460-3ayc0hne	400	7	into	into	IN
cord-006460-3ayc0hne	400	8	normal	normal	JJ
cord-006460-3ayc0hne	400	9	human	human	JJ
cord-006460-3ayc0hne	400	10	volunteers	volunteer	NNS
cord-006460-3ayc0hne	400	11	increased	increase	VBD
cord-006460-3ayc0hne	400	12	cardiac	cardiac	JJ
cord-006460-3ayc0hne	400	13	regularity	regularity	NN
cord-006460-3ayc0hne	400	14	[	[	-LRB-
cord-006460-3ayc0hne	400	15	122	122	CD
cord-006460-3ayc0hne	400	16	]	]	-RRB-
cord-006460-3ayc0hne	400	17	.	.	.
cord-006460-3ayc0hne	401	1	Godin	Godin	NNP
cord-006460-3ayc0hne	401	2	and	and	CC
cord-006460-3ayc0hne	401	3	Buchman	Buchman	NNP
cord-006460-3ayc0hne	401	4	stated	state	VBD
cord-006460-3ayc0hne	401	5	that	that	IN
cord-006460-3ayc0hne	401	6	"	"	``
cord-006460-3ayc0hne	401	7	a	a	DT
cord-006460-3ayc0hne	401	8	nonlinear	nonlinear	JJ
cord-006460-3ayc0hne	401	9	system	system	NN
cord-006460-3ayc0hne	401	10	is	be	VBZ
cord-006460-3ayc0hne	401	11	one	one	CD
cord-006460-3ayc0hne	401	12	whose	whose	WP$
cord-006460-3ayc0hne	401	13	behavior	behavior	NN
cord-006460-3ayc0hne	401	14	is	be	VBZ
cord-006460-3ayc0hne	401	15	not	not	RB
cord-006460-3ayc0hne	401	16	a	a	DT
cord-006460-3ayc0hne	401	17	simple	simple	JJ
cord-006460-3ayc0hne	401	18	sum	sum	NN
cord-006460-3ayc0hne	401	19	or	or	CC
cord-006460-3ayc0hne	401	20	multiples	multiple	NNS
cord-006460-3ayc0hne	401	21	of	of	IN
cord-006460-3ayc0hne	401	22	the	the	DT
cord-006460-3ayc0hne	401	23	inputs	input	NNS
cord-006460-3ayc0hne	401	24	to	to	IN
cord-006460-3ayc0hne	401	25	the	the	DT
cord-006460-3ayc0hne	401	26	system	system	NN
cord-006460-3ayc0hne	401	27	.	.	.
cord-006460-3ayc0hne	402	1	Chaos	chaos	NN
cord-006460-3ayc0hne	402	2	is	be	VBZ
cord-006460-3ayc0hne	402	3	irregular	irregular	JJ
cord-006460-3ayc0hne	402	4	behavior	behavior	NN
cord-006460-3ayc0hne	402	5	of	of	IN
cord-006460-3ayc0hne	402	6	some	some	DT
cord-006460-3ayc0hne	402	7	deterministic	deterministic	JJ
cord-006460-3ayc0hne	402	8	,	,	,
cord-006460-3ayc0hne	402	9	nonlinear	nonlinear	JJ
cord-006460-3ayc0hne	402	10	systems	system	NNS
cord-006460-3ayc0hne	402	11	"	"	''
cord-006460-3ayc0hne	402	12	[	[	-LRB-
cord-006460-3ayc0hne	402	13	123	123	CD
cord-006460-3ayc0hne	402	14	]	]	-RRB-
cord-006460-3ayc0hne	402	15	.	.	.
cord-006460-3ayc0hne	403	1	They	-PRON-	PRP
cord-006460-3ayc0hne	403	2	proposed	propose	VBD
cord-006460-3ayc0hne	403	3	a	a	DT
cord-006460-3ayc0hne	403	4	theory	theory	NN
cord-006460-3ayc0hne	403	5	of	of	IN
cord-006460-3ayc0hne	403	6	uncoupling	uncoupling	NN
cord-006460-3ayc0hne	403	7	of	of	IN
cord-006460-3ayc0hne	403	8	biologic	biologic	JJ
cord-006460-3ayc0hne	403	9	oscillators	oscillator	NNS
cord-006460-3ayc0hne	403	10	to	to	TO
cord-006460-3ayc0hne	403	11	progress	progress	VB
cord-006460-3ayc0hne	403	12	from	from	IN
cord-006460-3ayc0hne	403	13	SIRS	SIRS	NNP
cord-006460-3ayc0hne	403	14	to	to	IN
cord-006460-3ayc0hne	403	15	MODS	mod	NNS
cord-006460-3ayc0hne	403	16	.	.	.
cord-006460-3ayc0hne	404	1	Biologic	biologic	JJ
cord-006460-3ayc0hne	404	2	systems	system	NNS
cord-006460-3ayc0hne	404	3	are	be	VBP
cord-006460-3ayc0hne	404	4	always	always	RB
cord-006460-3ayc0hne	404	5	coupling	couple	VBG
cord-006460-3ayc0hne	404	6	and	and	CC
cord-006460-3ayc0hne	404	7	uncoupling	uncoupling	JJ
cord-006460-3ayc0hne	404	8	(	(	-LRB-
cord-006460-3ayc0hne	404	9	multiple	multiple	JJ
cord-006460-3ayc0hne	404	10	stable	stable	JJ
cord-006460-3ayc0hne	404	11	states	state	NNS
cord-006460-3ayc0hne	404	12	)	)	-RRB-
cord-006460-3ayc0hne	404	13	.	.	.
cord-006460-3ayc0hne	405	1	Disease	Disease	NNP
cord-006460-3ayc0hne	405	2	is	be	VBZ
cord-006460-3ayc0hne	405	3	a	a	DT
cord-006460-3ayc0hne	405	4	failure	failure	NN
cord-006460-3ayc0hne	405	5	to	to	IN
cord-006460-3ayc0hne	405	6	recouple	recouple	NNP
cord-006460-3ayc0hne	405	7	.	.	.
cord-006460-3ayc0hne	406	1	Thus	thus	RB
cord-006460-3ayc0hne	406	2	,	,	,
cord-006460-3ayc0hne	406	3	the	the	DT
cord-006460-3ayc0hne	406	4	physiologic	physiologic	JJ
cord-006460-3ayc0hne	406	5	states	state	NNS
cord-006460-3ayc0hne	406	6	described	describe	VBN
cord-006460-3ayc0hne	406	7	by	by	IN
cord-006460-3ayc0hne	406	8	Siegel	Siegel	NNP
cord-006460-3ayc0hne	406	9	et	et	NNP
cord-006460-3ayc0hne	406	10	al	al	NNP
cord-006460-3ayc0hne	406	11	.	.	.
cord-006460-3ayc0hne	407	1	[	[	-LRB-
cord-006460-3ayc0hne	407	2	124	124	CD
cord-006460-3ayc0hne	407	3	]	]	-RRB-
cord-006460-3ayc0hne	407	4	may	may	MD
cord-006460-3ayc0hne	407	5	be	be	VB
cord-006460-3ayc0hne	407	6	a	a	DT
cord-006460-3ayc0hne	407	7	better	well	JJR
cord-006460-3ayc0hne	407	8	way	way	NN
cord-006460-3ayc0hne	407	9	to	to	TO
cord-006460-3ayc0hne	407	10	describe	describe	VB
cord-006460-3ayc0hne	407	11	and	and	CC
cord-006460-3ayc0hne	407	12	treat	treat	VB
cord-006460-3ayc0hne	407	13	human	human	JJ
cord-006460-3ayc0hne	407	14	problems	problem	NNS
cord-006460-3ayc0hne	407	15	.	.	.
cord-006460-3ayc0hne	408	1	In	in	IN
cord-006460-3ayc0hne	408	2	the	the	DT
cord-006460-3ayc0hne	408	3	meantime	meantime	NN
cord-006460-3ayc0hne	408	4	,	,	,
cord-006460-3ayc0hne	408	5	we	-PRON-	PRP
cord-006460-3ayc0hne	408	6	have	have	VBP
cord-006460-3ayc0hne	408	7	much	much	JJ
cord-006460-3ayc0hne	408	8	to	to	TO
cord-006460-3ayc0hne	408	9	learn	learn	VB
cord-006460-3ayc0hne	408	10	about	about	IN
cord-006460-3ayc0hne	408	11	how	how	WRB
cord-006460-3ayc0hne	408	12	non	non	JJ
cord-006460-3ayc0hne	408	13	-	-	JJ
cord-006460-3ayc0hne	408	14	linear	linear	JJ
cord-006460-3ayc0hne	408	15	integrative	integrative	JJ
cord-006460-3ayc0hne	408	16	biology	biology	NN
cord-006460-3ayc0hne	408	17	will	will	MD
cord-006460-3ayc0hne	408	18	help	help	VB
cord-006460-3ayc0hne	408	19	us	-PRON-	PRP
cord-006460-3ayc0hne	408	20	to	to	TO
cord-006460-3ayc0hne	408	21	solve	solve	VB
cord-006460-3ayc0hne	408	22	clinical	clinical	JJ
cord-006460-3ayc0hne	408	23	problems	problem	NNS
cord-006460-3ayc0hne	408	24	.	.	.
cord-006460-3ayc0hne	409	1	The	the	DT
cord-006460-3ayc0hne	409	2	discrepancy	discrepancy	NN
cord-006460-3ayc0hne	409	3	between	between	IN
cord-006460-3ayc0hne	409	4	what	what	WP
cord-006460-3ayc0hne	409	5	we	-PRON-	PRP
cord-006460-3ayc0hne	409	6	are	be	VBP
cord-006460-3ayc0hne	409	7	learning	learn	VBG
cord-006460-3ayc0hne	409	8	in	in	IN
cord-006460-3ayc0hne	409	9	molecular	molecular	JJ
cord-006460-3ayc0hne	409	10	biology	biology	NN
cord-006460-3ayc0hne	409	11	and	and	CC
cord-006460-3ayc0hne	409	12	what	what	WP
cord-006460-3ayc0hne	409	13	we	-PRON-	PRP
cord-006460-3ayc0hne	409	14	can	can	MD
cord-006460-3ayc0hne	409	15	do	do	VB
cord-006460-3ayc0hne	409	16	for	for	IN
cord-006460-3ayc0hne	409	17	our	-PRON-	PRP$
cord-006460-3ayc0hne	409	18	patients	patient	NNS
cord-006460-3ayc0hne	409	19	is	be	VBZ
cord-006460-3ayc0hne	409	20	great	great	JJ
cord-006460-3ayc0hne	409	21	.	.	.
cord-006460-3ayc0hne	410	1	The	the	DT
cord-006460-3ayc0hne	410	2	science	science	NN
cord-006460-3ayc0hne	410	3	is	be	VBZ
cord-006460-3ayc0hne	410	4	exciting	exciting	JJ
cord-006460-3ayc0hne	410	5	,	,	,
cord-006460-3ayc0hne	410	6	very	very	RB
cord-006460-3ayc0hne	410	7	worthwhile	worthwhile	JJ
cord-006460-3ayc0hne	410	8	,	,	,
cord-006460-3ayc0hne	410	9	and	and	CC
cord-006460-3ayc0hne	410	10	should	should	MD
cord-006460-3ayc0hne	410	11	be	be	VB
cord-006460-3ayc0hne	410	12	encouraged	encourage	VBN
cord-006460-3ayc0hne	410	13	.	.	.
cord-006460-3ayc0hne	411	1	Eventually	eventually	RB
cord-006460-3ayc0hne	411	2	it	-PRON-	PRP
cord-006460-3ayc0hne	411	3	will	will	MD
cord-006460-3ayc0hne	411	4	make	make	VB
cord-006460-3ayc0hne	411	5	contributions	contribution	NNS
cord-006460-3ayc0hne	411	6	to	to	IN
cord-006460-3ayc0hne	411	7	health	health	NN
cord-006460-3ayc0hne	411	8	and	and	CC
cord-006460-3ayc0hne	411	9	patient	patient	NN
cord-006460-3ayc0hne	411	10	care	care	NN
cord-006460-3ayc0hne	411	11	.	.	.
cord-006460-3ayc0hne	412	1	In	in	IN
cord-006460-3ayc0hne	412	2	the	the	DT
cord-006460-3ayc0hne	412	3	meantime	meantime	NN
cord-006460-3ayc0hne	412	4	,	,	,
cord-006460-3ayc0hne	412	5	we	-PRON-	PRP
cord-006460-3ayc0hne	412	6	must	must	MD
cord-006460-3ayc0hne	412	7	focus	focus	VB
cord-006460-3ayc0hne	412	8	on	on	IN
cord-006460-3ayc0hne	412	9	better	well	JJR
cord-006460-3ayc0hne	412	10	and	and	CC
cord-006460-3ayc0hne	412	11	safer	safe	JJR
cord-006460-3ayc0hne	412	12	operations	operation	NNS
cord-006460-3ayc0hne	412	13	,	,	,
cord-006460-3ayc0hne	412	14	better	well	JJR
cord-006460-3ayc0hne	412	15	treatment	treatment	NN
cord-006460-3ayc0hne	412	16	of	of	IN
cord-006460-3ayc0hne	412	17	injury	injury	NN
cord-006460-3ayc0hne	412	18	,	,	,
cord-006460-3ayc0hne	412	19	and	and	CC
cord-006460-3ayc0hne	412	20	clinical	clinical	JJ
cord-006460-3ayc0hne	412	21	research	research	NN
cord-006460-3ayc0hne	412	22	to	to	TO
cord-006460-3ayc0hne	412	23	improve	improve	VB
cord-006460-3ayc0hne	412	24	care	care	NN
cord-006460-3ayc0hne	412	25	and	and	CC
cord-006460-3ayc0hne	412	26	decrease	decrease	VB
cord-006460-3ayc0hne	412	27	morbidity	morbidity	NN
cord-006460-3ayc0hne	412	28	and	and	CC
cord-006460-3ayc0hne	412	29	mortality	mortality	NN
cord-006460-3ayc0hne	412	30	.	.	.
cord-006460-3ayc0hne	413	1	We	-PRON-	PRP
cord-006460-3ayc0hne	413	2	must	must	MD
cord-006460-3ayc0hne	413	3	avoid	avoid	VB
cord-006460-3ayc0hne	413	4	exaggerating	exaggerate	VBG
cord-006460-3ayc0hne	413	5	the	the	DT
cord-006460-3ayc0hne	413	6	results	result	NNS
cord-006460-3ayc0hne	413	7	and	and	CC
cord-006460-3ayc0hne	413	8	significance	significance	NN
cord-006460-3ayc0hne	413	9	of	of	IN
cord-006460-3ayc0hne	413	10	animal	animal	NN
cord-006460-3ayc0hne	413	11	research	research	NN
cord-006460-3ayc0hne	413	12	because	because	IN
cord-006460-3ayc0hne	413	13	it	-PRON-	PRP
cord-006460-3ayc0hne	413	14	may	may	MD
cord-006460-3ayc0hne	413	15	not	not	RB
cord-006460-3ayc0hne	413	16	apply	apply	VB
cord-006460-3ayc0hne	413	17	to	to	IN
cord-006460-3ayc0hne	413	18	man	man	NN
cord-006460-3ayc0hne	413	19	.	.	.
cord-006460-3ayc0hne	414	1	All	all	DT
cord-006460-3ayc0hne	414	2	of	of	IN
cord-006460-3ayc0hne	414	3	us	-PRON-	PRP
cord-006460-3ayc0hne	414	4	remember	remember	VBP
cord-006460-3ayc0hne	414	5	exciting	exciting	JJ
cord-006460-3ayc0hne	414	6	experiments	experiment	NNS
cord-006460-3ayc0hne	414	7	in	in	IN
cord-006460-3ayc0hne	414	8	the	the	DT
cord-006460-3ayc0hne	414	9	laboratory	laboratory	NN
cord-006460-3ayc0hne	414	10	that	that	WDT
cord-006460-3ayc0hne	414	11	have	have	VBP
cord-006460-3ayc0hne	414	12	never	never	RB
cord-006460-3ayc0hne	414	13	helped	help	VBN
cord-006460-3ayc0hne	414	14	patients	patient	NNS
cord-006460-3ayc0hne	414	15	.	.	.
cord-006460-3ayc0hne	415	1	Our	-PRON-	PRP$
cord-006460-3ayc0hne	415	2	research	research	NN
cord-006460-3ayc0hne	415	3	may	may	MD
cord-006460-3ayc0hne	415	4	eliminate	eliminate	VB
cord-006460-3ayc0hne	415	5	the	the	DT
cord-006460-3ayc0hne	415	6	need	need	NN
cord-006460-3ayc0hne	415	7	for	for	IN
cord-006460-3ayc0hne	415	8	an	an	DT
cord-006460-3ayc0hne	415	9	operation	operation	NN
cord-006460-3ayc0hne	415	10	.	.	.
cord-006460-3ayc0hne	416	1	Professor	Professor	NNP
cord-006460-3ayc0hne	416	2	Edward	Edward	NNP
cord-006460-3ayc0hne	416	3	D.	D.	NNP
cord-006460-3ayc0hne	416	4	Churchill	Churchill	NNP
cord-006460-3ayc0hne	416	5	[	[	-LRB-
cord-006460-3ayc0hne	416	6	125	125	CD
cord-006460-3ayc0hne	416	7	]	]	-RRB-
cord-006460-3ayc0hne	416	8	at	at	IN
cord-006460-3ayc0hne	416	9	Harvard	Harvard	NNP
cord-006460-3ayc0hne	416	10	and	and	CC
cord-006460-3ayc0hne	416	11	the	the	DT
cord-006460-3ayc0hne	416	12	Massachusetts	Massachusetts	NNP
cord-006460-3ayc0hne	416	13	General	General	NNP
cord-006460-3ayc0hne	416	14	Hospital	Hospital	NNP
cord-006460-3ayc0hne	416	15	in	in	IN
cord-006460-3ayc0hne	416	16	Boston	Boston	NNP
cord-006460-3ayc0hne	416	17	once	once	RB
cord-006460-3ayc0hne	416	18	stated	state	VBD
cord-006460-3ayc0hne	416	19	that	that	IN
cord-006460-3ayc0hne	416	20	,	,	,
cord-006460-3ayc0hne	416	21	"	"	``
cord-006460-3ayc0hne	416	22	Surgery	surgery	NN
cord-006460-3ayc0hne	416	23	began	begin	VBD
cord-006460-3ayc0hne	416	24	with	with	IN
cord-006460-3ayc0hne	416	25	trauma	trauma	NN
cord-006460-3ayc0hne	416	26	and	and	CC
cord-006460-3ayc0hne	416	27	congenital	congenital	JJ
cord-006460-3ayc0hne	416	28	anomalies	anomaly	NNS
cord-006460-3ayc0hne	416	29	and	and	CC
cord-006460-3ayc0hne	416	30	therein	therein	RB
cord-006460-3ayc0hne	416	31	shall	shall	MD
cord-006460-3ayc0hne	416	32	it	-PRON-	PRP
cord-006460-3ayc0hne	416	33	end	end	VB
cord-006460-3ayc0hne	416	34	.	.	.
cord-006460-3ayc0hne	416	35	"	"	''
cord-006460-3ayc0hne	417	1	Even	even	RB
cord-006460-3ayc0hne	417	2	congenital	congenital	JJ
cord-006460-3ayc0hne	417	3	anomalies	anomaly	NNS
cord-006460-3ayc0hne	417	4	may	may	MD
cord-006460-3ayc0hne	417	5	be	be	VB
cord-006460-3ayc0hne	417	6	prevented	prevent	VBN
cord-006460-3ayc0hne	417	7	or	or	CC
cord-006460-3ayc0hne	417	8	treated	treat	VBN
cord-006460-3ayc0hne	417	9	in	in	IN
cord-006460-3ayc0hne	417	10	utero	utero	NNS
cord-006460-3ayc0hne	417	11	.	.	.
cord-006460-3ayc0hne	418	1	Angioplasty	angioplasty	NN
cord-006460-3ayc0hne	418	2	with	with	IN
cord-006460-3ayc0hne	418	3	stents	stent	NNS
cord-006460-3ayc0hne	418	4	may	may	MD
cord-006460-3ayc0hne	418	5	eventually	eventually	RB
cord-006460-3ayc0hne	418	6	take	take	VB
cord-006460-3ayc0hne	418	7	the	the	DT
cord-006460-3ayc0hne	418	8	place	place	NN
cord-006460-3ayc0hne	418	9	of	of	IN
cord-006460-3ayc0hne	418	10	coronary	coronary	JJ
cord-006460-3ayc0hne	418	11	bypass	bypass	NN
cord-006460-3ayc0hne	418	12	grafting	grafting	NN
cord-006460-3ayc0hne	418	13	.	.	.
cord-006460-3ayc0hne	419	1	Many	many	JJ
cord-006460-3ayc0hne	419	2	years	year	NNS
cord-006460-3ayc0hne	419	3	ago	ago	RB
cord-006460-3ayc0hne	419	4	,	,	,
cord-006460-3ayc0hne	419	5	antibiotics	antibiotic	NNS
cord-006460-3ayc0hne	419	6	eliminated	eliminate	VBD
cord-006460-3ayc0hne	419	7	the	the	DT
cord-006460-3ayc0hne	419	8	need	need	NN
cord-006460-3ayc0hne	419	9	for	for	IN
cord-006460-3ayc0hne	419	10	mastoidectomies	mastoidectomy	NNS
cord-006460-3ayc0hne	419	11	,	,	,
cord-006460-3ayc0hne	419	12	but	but	CC
cord-006460-3ayc0hne	419	13	otolaryngologists	otolaryngologist	NNS
cord-006460-3ayc0hne	419	14	went	go	VBD
cord-006460-3ayc0hne	419	15	on	on	RP
cord-006460-3ayc0hne	419	16	to	to	IN
cord-006460-3ayc0hne	419	17	other	other	JJ
cord-006460-3ayc0hne	419	18	things	thing	NNS
cord-006460-3ayc0hne	419	19	.	.	.
cord-006460-3ayc0hne	420	1	We	-PRON-	PRP
cord-006460-3ayc0hne	420	2	must	must	MD
cord-006460-3ayc0hne	420	3	be	be	VB
cord-006460-3ayc0hne	420	4	cautious	cautious	JJ
cord-006460-3ayc0hne	420	5	about	about	IN
cord-006460-3ayc0hne	420	6	so	so	RB
cord-006460-3ayc0hne	420	7	-	-	HYPH
cord-006460-3ayc0hne	420	8	called	call	VBN
cord-006460-3ayc0hne	420	9	"	"	``
cord-006460-3ayc0hne	420	10	magic	magic	JJ
cord-006460-3ayc0hne	420	11	bullets	bullet	NNS
cord-006460-3ayc0hne	420	12	"	"	''
cord-006460-3ayc0hne	420	13	and	and	CC
cord-006460-3ayc0hne	420	14	remember	remember	VB
cord-006460-3ayc0hne	420	15	the	the	DT
cord-006460-3ayc0hne	420	16	differences	difference	NNS
cord-006460-3ayc0hne	420	17	in	in	IN
cord-006460-3ayc0hne	420	18	individuals	individual	NNS
cord-006460-3ayc0hne	420	19	,	,	,
cord-006460-3ayc0hne	420	20	both	both	CC
cord-006460-3ayc0hne	420	21	in	in	IN
cord-006460-3ayc0hne	420	22	terms	term	NNS
cord-006460-3ayc0hne	420	23	of	of	IN
cord-006460-3ayc0hne	420	24	genetics	genetic	NNS
cord-006460-3ayc0hne	420	25	and	and	CC
cord-006460-3ayc0hne	420	26	in	in	IN
cord-006460-3ayc0hne	420	27	life	life	NN
cord-006460-3ayc0hne	420	28	experiences	experience	NNS
cord-006460-3ayc0hne	420	29	.	.	.
cord-006460-3ayc0hne	421	1	We	-PRON-	PRP
cord-006460-3ayc0hne	421	2	must	must	MD
cord-006460-3ayc0hne	421	3	treat	treat	VB
cord-006460-3ayc0hne	421	4	disease	disease	NN
cord-006460-3ayc0hne	421	5	,	,	,
cord-006460-3ayc0hne	421	6	not	not	RB
cord-006460-3ayc0hne	421	7	concepts	concept	NNS
cord-006460-3ayc0hne	421	8	of	of	IN
cord-006460-3ayc0hne	421	9	inflammation	inflammation	NN
cord-006460-3ayc0hne	421	10	or	or	CC
cord-006460-3ayc0hne	421	11	of	of	IN
cord-006460-3ayc0hne	421	12	being	be	VBG
cord-006460-3ayc0hne	421	13	sick	sick	JJ
cord-006460-3ayc0hne	421	14	.	.	.
cord-006460-3ayc0hne	422	1	We	-PRON-	PRP
cord-006460-3ayc0hne	422	2	must	must	MD
cord-006460-3ayc0hne	422	3	be	be	VB
cord-006460-3ayc0hne	422	4	careful	careful	JJ
cord-006460-3ayc0hne	422	5	about	about	IN
cord-006460-3ayc0hne	422	6	"	"	``
cord-006460-3ayc0hne	422	7	academically	academically	RB
cord-006460-3ayc0hne	422	8	-	-	HYPH
cord-006460-3ayc0hne	422	9	correct	correct	JJ
cord-006460-3ayc0hne	422	10	biology	biology	NN
cord-006460-3ayc0hne	422	11	,	,	,
cord-006460-3ayc0hne	422	12	"	"	''
cord-006460-3ayc0hne	422	13	as	as	IN
cord-006460-3ayc0hne	422	14	described	describe	VBN
cord-006460-3ayc0hne	422	15	by	by	IN
cord-006460-3ayc0hne	422	16	Vogel	Vogel	NNP
cord-006460-3ayc0hne	422	17	[	[	-LRB-
cord-006460-3ayc0hne	422	18	126	126	CD
cord-006460-3ayc0hne	422	19	]	]	-RRB-
cord-006460-3ayc0hne	422	20	:	:	:
cord-006460-3ayc0hne	422	21	"	"	``
cord-006460-3ayc0hne	422	22	(	(	-LRB-
cord-006460-3ayc0hne	422	23	1	1	LS
cord-006460-3ayc0hne	422	24	)	)	-RRB-
cord-006460-3ayc0hne	422	25	It	-PRON-	PRP
cord-006460-3ayc0hne	422	26	seeks	seek	VBZ
cord-006460-3ayc0hne	422	27	molecular	molecular	JJ
cord-006460-3ayc0hne	422	28	explanations	explanation	NNS
cord-006460-3ayc0hne	422	29	;	;	,
cord-006460-3ayc0hne	422	30	(	(	-LRB-
cord-006460-3ayc0hne	422	31	2	2	LS
cord-006460-3ayc0hne	422	32	)	)	-RRB-
cord-006460-3ayc0hne	422	33	It	-PRON-	PRP
cord-006460-3ayc0hne	422	34	views	view	VBZ
cord-006460-3ayc0hne	422	35	scientific	scientific	JJ
cord-006460-3ayc0hne	422	36	progress	progress	NN
cord-006460-3ayc0hne	422	37	as	as	IN
cord-006460-3ayc0hne	422	38	incremental	incremental	JJ
cord-006460-3ayc0hne	422	39	accretion	accretion	NN
cord-006460-3ayc0hne	422	40	of	of	IN
cord-006460-3ayc0hne	422	41	detail	detail	NN
cord-006460-3ayc0hne	422	42	;	;	:
cord-006460-3ayc0hne	422	43	(	(	-LRB-
cord-006460-3ayc0hne	422	44	3	3	LS
cord-006460-3ayc0hne	422	45	)	)	-RRB-
cord-006460-3ayc0hne	423	1	The	the	DT
cord-006460-3ayc0hne	423	2	immediate	immediate	JJ
cord-006460-3ayc0hne	423	3	goal	goal	NN
cord-006460-3ayc0hne	423	4	is	be	VBZ
cord-006460-3ayc0hne	423	5	human	human	JJ
cord-006460-3ayc0hne	423	6	therapy	therapy	NN
cord-006460-3ayc0hne	423	7	;	;	:
cord-006460-3ayc0hne	423	8	(	(	-LRB-
cord-006460-3ayc0hne	423	9	4	4	LS
cord-006460-3ayc0hne	423	10	)	)	-RRB-
cord-006460-3ayc0hne	424	1	Its	-PRON-	PRP$
cord-006460-3ayc0hne	424	2	operation	operation	NN
cord-006460-3ayc0hne	424	3	is	be	VBZ
cord-006460-3ayc0hne	424	4	unabashedly	unabashedly	RB
cord-006460-3ayc0hne	424	5	entrepreneurial	entrepreneurial	JJ
cord-006460-3ayc0hne	424	6	.	.	.
cord-006460-3ayc0hne	424	7	"	"	''
cord-006460-3ayc0hne	425	1	Latour	Latour	NNP
cord-006460-3ayc0hne	425	2	[	[	-LRB-
cord-006460-3ayc0hne	425	3	127	127	CD
cord-006460-3ayc0hne	425	4	]	]	-RRB-
cord-006460-3ayc0hne	425	5	stated	state	VBD
cord-006460-3ayc0hne	425	6	that	that	IN
cord-006460-3ayc0hne	425	7	,	,	,
cord-006460-3ayc0hne	425	8	"	"	``
cord-006460-3ayc0hne	425	9	Science	science	NN
cord-006460-3ayc0hne	425	10	does	do	VBZ
cord-006460-3ayc0hne	425	11	not	not	RB
cord-006460-3ayc0hne	425	12	enter	enter	VB
cord-006460-3ayc0hne	425	13	a	a	DT
cord-006460-3ayc0hne	425	14	chaotic	chaotic	JJ
cord-006460-3ayc0hne	425	15	society	society	NN
cord-006460-3ayc0hne	425	16	to	to	TO
cord-006460-3ayc0hne	425	17	put	put	VB
cord-006460-3ayc0hne	425	18	order	order	NN
cord-006460-3ayc0hne	425	19	into	into	IN
cord-006460-3ayc0hne	425	20	it	-PRON-	PRP
cord-006460-3ayc0hne	425	21	anymore	anymore	RB
cord-006460-3ayc0hne	425	22	but	but	CC
cord-006460-3ayc0hne	425	23	to	to	TO
cord-006460-3ayc0hne	425	24	add	add	VB
cord-006460-3ayc0hne	425	25	new	new	JJ
cord-006460-3ayc0hne	425	26	,	,	,
cord-006460-3ayc0hne	425	27	uncertain	uncertain	JJ
cord-006460-3ayc0hne	425	28	ingredients	ingredient	NNS
cord-006460-3ayc0hne	425	29	-to	-to	:
cord-006460-3ayc0hne	425	30	the	the	DT
cord-006460-3ayc0hne	425	31	collective	collective	JJ
cord-006460-3ayc0hne	425	32	process	process	NN
cord-006460-3ayc0hne	425	33	.	.	.
cord-006460-3ayc0hne	425	34	"	"	''
cord-006460-3ayc0hne	426	1	Claude	Claude	NNP
cord-006460-3ayc0hne	426	2	Lenfant	Lenfant	NNP
cord-006460-3ayc0hne	426	3	[	[	-LRB-
cord-006460-3ayc0hne	426	4	128	128	CD
cord-006460-3ayc0hne	426	5	]	]	-RRB-
cord-006460-3ayc0hne	426	6	,	,	,
cord-006460-3ayc0hne	426	7	Director	Director	NNP
cord-006460-3ayc0hne	426	8	of	of	IN
cord-006460-3ayc0hne	426	9	the	the	DT
cord-006460-3ayc0hne	426	10	National	National	NNP
cord-006460-3ayc0hne	426	11	Heart	Heart	NNP
cord-006460-3ayc0hne	426	12	,	,	,
cord-006460-3ayc0hne	426	13	Lung	Lung	NNP
cord-006460-3ayc0hne	426	14	and	and	CC
cord-006460-3ayc0hne	426	15	Blood	Blood	NNP
cord-006460-3ayc0hne	426	16	Institute	Institute	NNP
cord-006460-3ayc0hne	426	17	of	of	IN
cord-006460-3ayc0hne	426	18	the	the	DT
cord-006460-3ayc0hne	426	19	National	National	NNP
cord-006460-3ayc0hne	426	20	Institutes	Institutes	NNPS
cord-006460-3ayc0hne	426	21	of	of	IN
cord-006460-3ayc0hne	426	22	Health	Health	NNP
cord-006460-3ayc0hne	426	23	(	(	-LRB-
cord-006460-3ayc0hne	427	1	NHL&B	NHL&B	NNP
cord-006460-3ayc0hne	427	2	)	)	-RRB-
cord-006460-3ayc0hne	427	3	,	,	,
cord-006460-3ayc0hne	427	4	stated	state	VBD
cord-006460-3ayc0hne	427	5	that	that	IN
cord-006460-3ayc0hne	427	6	,	,	,
cord-006460-3ayc0hne	427	7	"	"	``
cord-006460-3ayc0hne	427	8	The	the	DT
cord-006460-3ayc0hne	427	9	real	real	JJ
cord-006460-3ayc0hne	427	10	challenge	challenge	NN
cord-006460-3ayc0hne	427	11	of	of	IN
cord-006460-3ayc0hne	427	12	the	the	DT
cord-006460-3ayc0hne	427	13	new	new	JJ
cord-006460-3ayc0hne	427	14	millennium	millennium	NN
cord-006460-3ayc0hne	427	15	may	may	MD
cord-006460-3ayc0hne	427	16	indeed	indeed	RB
cord-006460-3ayc0hne	427	17	be	be	VB
cord-006460-3ayc0hne	427	18	to	to	TO
cord-006460-3ayc0hne	427	19	strike	strike	VB
cord-006460-3ayc0hne	427	20	an	an	DT
cord-006460-3ayc0hne	427	21	appropriate	appropriate	JJ
cord-006460-3ayc0hne	427	22	balance	balance	NN
cord-006460-3ayc0hne	427	23	between	between	IN
cord-006460-3ayc0hne	427	24	the	the	DT
cord-006460-3ayc0hne	427	25	pursuit	pursuit	NN
cord-006460-3ayc0hne	427	26	of	of	IN
cord-006460-3ayc0hne	427	27	exciting	exciting	JJ
cord-006460-3ayc0hne	427	28	new	new	JJ
cord-006460-3ayc0hne	427	29	knowledge	knowledge	NN
cord-006460-3ayc0hne	427	30	and	and	CC
cord-006460-3ayc0hne	427	31	the	the	DT
cord-006460-3ayc0hne	427	32	full	full	JJ
cord-006460-3ayc0hne	427	33	application	application	NN
cord-006460-3ayc0hne	427	34	of	of	IN
cord-006460-3ayc0hne	427	35	strategies	strategy	NNS
cord-006460-3ayc0hne	427	36	that	that	WDT
cord-006460-3ayc0hne	427	37	are	be	VBP
cord-006460-3ayc0hne	427	38	already	already	RB
cord-006460-3ayc0hne	427	39	known	know	VBN
cord-006460-3ayc0hne	427	40	to	to	TO
cord-006460-3ayc0hne	427	41	be	be	VB
cord-006460-3ayc0hne	427	42	extremely	extremely	RB
cord-006460-3ayc0hne	427	43	effective	effective	JJ
cord-006460-3ayc0hne	427	44	but	but	CC
cord-006460-3ayc0hne	427	45	considerably	considerably	RB
cord-006460-3ayc0hne	427	46	underused	underused	JJ
cord-006460-3ayc0hne	427	47	.	.	.
cord-006460-3ayc0hne	428	1	"	"	''
cord-006460-3ayc0hne	429	1	Finally	finally	RB
cord-006460-3ayc0hne	429	2	,	,	,
cord-006460-3ayc0hne	429	3	I	-PRON-	PRP
cord-006460-3ayc0hne	429	4	have	have	VBP
cord-006460-3ayc0hne	429	5	paraphrased	paraphrase	VBN
cord-006460-3ayc0hne	429	6	a	a	DT
cord-006460-3ayc0hne	429	7	section	section	NN
cord-006460-3ayc0hne	429	8	of	of	IN
cord-006460-3ayc0hne	429	9	the	the	DT
cord-006460-3ayc0hne	429	10	Old	Old	NNP
cord-006460-3ayc0hne	429	11	Testament	Testament	NNP
cord-006460-3ayc0hne	429	12	,	,	,
cord-006460-3ayc0hne	429	13	Ecclesiastes	Ecclesiastes	NNP
cord-006460-3ayc0hne	429	14	3:1	3:1	CD
cord-006460-3ayc0hne	429	15	[	[	-LRB-
cord-006460-3ayc0hne	429	16	129	129	CD
cord-006460-3ayc0hne	429	17	]	]	-RRB-
cord-006460-3ayc0hne	429	18	:	:	:
cord-006460-3ayc0hne	430	1	There	there	EX
cord-006460-3ayc0hne	430	2	is	be	VBZ
cord-006460-3ayc0hne	430	3	a	a	DT
cord-006460-3ayc0hne	430	4	time	time	NN
cord-006460-3ayc0hne	430	5	for	for	IN
cord-006460-3ayc0hne	430	6	everything	everything	NN
cord-006460-3ayc0hne	430	7	and	and	CC
cord-006460-3ayc0hne	430	8	a	a	DT
cord-006460-3ayc0hne	430	9	season	season	NN
cord-006460-3ayc0hne	430	10	for	for	IN
cord-006460-3ayc0hne	430	11	every	every	DT
cord-006460-3ayc0hne	430	12	activity	activity	NN
cord-006460-3ayc0hne	430	13	under	under	IN
cord-006460-3ayc0hne	430	14	heaven	heaven	NNP
cord-006460-3ayc0hne	430	15	.	.	.
cord-006460-3ayc0hne	430	16	"	"	''
cord-006460-3ayc0hne	431	1	A	a	DT
cord-006460-3ayc0hne	431	2	time	time	NN
cord-006460-3ayc0hne	431	3	to	to	TO
cord-006460-3ayc0hne	431	4	be	be	VB
cord-006460-3ayc0hne	431	5	born	bear	VBN
cord-006460-3ayc0hne	431	6	and	and	CC
cord-006460-3ayc0hne	431	7	a	a	DT
cord-006460-3ayc0hne	431	8	time	time	NN
cord-006460-3ayc0hne	431	9	to	to	TO
cord-006460-3ayc0hne	431	10	die	die	VB
cord-006460-3ayc0hne	431	11	,	,	,
cord-006460-3ayc0hne	431	12	A	a	DT
cord-006460-3ayc0hne	431	13	time	time	NN
cord-006460-3ayc0hne	431	14	to	to	TO
cord-006460-3ayc0hne	431	15	plant	plant	VB
cord-006460-3ayc0hne	431	16	and	and	CC
cord-006460-3ayc0hne	431	17	a	a	DT
cord-006460-3ayc0hne	431	18	time	time	NN
cord-006460-3ayc0hne	431	19	to	to	TO
cord-006460-3ayc0hne	431	20	pluck	pluck	VB
cord-006460-3ayc0hne	431	21	up	up	RP
cord-006460-3ayc0hne	431	22	,	,	,
cord-006460-3ayc0hne	431	23	A	a	DT
cord-006460-3ayc0hne	431	24	time	time	NN
cord-006460-3ayc0hne	431	25	to	to	TO
cord-006460-3ayc0hne	431	26	weep	weep	VB
cord-006460-3ayc0hne	431	27	and	and	CC
cord-006460-3ayc0hne	431	28	a	a	DT
cord-006460-3ayc0hne	431	29	time	time	NN
cord-006460-3ayc0hne	431	30	to	to	TO
cord-006460-3ayc0hne	431	31	laugh	laugh	VB
cord-006460-3ayc0hne	431	32	,	,	,
cord-006460-3ayc0hne	431	33	A	a	DT
cord-006460-3ayc0hne	431	34	time	time	NN
cord-006460-3ayc0hne	431	35	to	to	TO
cord-006460-3ayc0hne	431	36	mourn	mourn	VB
cord-006460-3ayc0hne	431	37	and	and	CC
cord-006460-3ayc0hne	431	38	a	a	DT
cord-006460-3ayc0hne	431	39	time	time	NN
cord-006460-3ayc0hne	431	40	to	to	TO
cord-006460-3ayc0hne	431	41	dance	dance	VB
cord-006460-3ayc0hne	431	42	,	,	,
cord-006460-3ayc0hne	431	43	A	a	DT
cord-006460-3ayc0hne	431	44	time	time	NN
cord-006460-3ayc0hne	431	45	of	of	IN
cord-006460-3ayc0hne	431	46	war	war	NN
cord-006460-3ayc0hne	431	47	and	and	CC
cord-006460-3ayc0hne	431	48	a	a	DT
cord-006460-3ayc0hne	431	49	time	time	NN
cord-006460-3ayc0hne	431	50	of	of	IN
cord-006460-3ayc0hne	431	51	peace	peace	NN
cord-006460-3ayc0hne	431	52	,	,	,
cord-006460-3ayc0hne	431	53	"	"	''
cord-006460-3ayc0hne	431	54	A	a	DT
cord-006460-3ayc0hne	431	55	time	time	NN
cord-006460-3ayc0hne	431	56	to	to	TO
cord-006460-3ayc0hne	431	57	give	give	VB
cord-006460-3ayc0hne	431	58	cytokines	cytokine	NNS
cord-006460-3ayc0hne	431	59	and	and	CC
cord-006460-3ayc0hne	431	60	a	a	DT
cord-006460-3ayc0hne	431	61	time	time	NN
cord-006460-3ayc0hne	431	62	to	to	TO
cord-006460-3ayc0hne	431	63	block	block	VB
cord-006460-3ayc0hne	431	64	cytokines	cytokine	NNS
cord-006460-3ayc0hne	431	65	,	,	,
cord-006460-3ayc0hne	431	66	A	a	DT
cord-006460-3ayc0hne	431	67	time	time	NN
cord-006460-3ayc0hne	431	68	to	to	TO
cord-006460-3ayc0hne	431	69	supplement	supplement	VB
cord-006460-3ayc0hne	431	70	and	and	CC
cord-006460-3ayc0hne	431	71	a	a	DT
cord-006460-3ayc0hne	431	72	time	time	NN
cord-006460-3ayc0hne	431	73	to	to	TO
cord-006460-3ayc0hne	431	74	modulate	modulate	VB
cord-006460-3ayc0hne	431	75	,	,	,
cord-006460-3ayc0hne	431	76	And	and	CC
cord-006460-3ayc0hne	431	77	a	a	DT
cord-006460-3ayc0hne	431	78	long	long	JJ
cord-006460-3ayc0hne	431	79	time	time	NN
cord-006460-3ayc0hne	431	80	to	to	TO
cord-006460-3ayc0hne	431	81	figure	figure	VB
cord-006460-3ayc0hne	431	82	out	out	RP
cord-006460-3ayc0hne	431	83	the	the	DT
cord-006460-3ayc0hne	431	84	time	time	NN
cord-006460-3ayc0hne	431	85	for	for	IN
cord-006460-3ayc0hne	431	86	any	any	DT
cord-006460-3ayc0hne	431	87	of	of	IN
cord-006460-3ayc0hne	431	88	these	these	DT
cord-006460-3ayc0hne	431	89	.	.	.
cord-006460-3ayc0hne	432	1	Then	then	RB
cord-006460-3ayc0hne	432	2	,	,	,
cord-006460-3ayc0hne	432	3	if	if	IN
cord-006460-3ayc0hne	432	4	successful	successful	JJ
cord-006460-3ayc0hne	432	5	,	,	,
cord-006460-3ayc0hne	432	6	the	the	DT
cord-006460-3ayc0hne	432	7	Lord	Lord	NNP
cord-006460-3ayc0hne	432	8	will	will	MD
cord-006460-3ayc0hne	432	9	invite	invite	VB
cord-006460-3ayc0hne	432	10	you	-PRON-	PRP
cord-006460-3ayc0hne	432	11	to	to	IN
cord-006460-3ayc0hne	432	12	Stockholm	Stockholm	NNP
cord-006460-3ayc0hne	432	13	and	and	CC
cord-006460-3ayc0hne	432	14	there	there	EX
cord-006460-3ayc0hne	432	15	will	will	MD
cord-006460-3ayc0hne	432	16	be	be	VB
cord-006460-3ayc0hne	432	17	a	a	DT
cord-006460-3ayc0hne	432	18	time	time	NN
cord-006460-3ayc0hne	432	19	for	for	IN
cord-006460-3ayc0hne	432	20	honor	honor	NN
cord-006460-3ayc0hne	432	21	.	.	.
cord-006460-3ayc0hne	433	1	On	on	IN
cord-006460-3ayc0hne	433	2	1	1	CD
cord-006460-3ayc0hne	433	3	and	and	CC
cord-006460-3ayc0hne	433	4	2	2	CD
cord-006460-3ayc0hne	433	5	March	March	NNP
cord-006460-3ayc0hne	433	6	2000	2000	CD
cord-006460-3ayc0hne	433	7	,	,	,
cord-006460-3ayc0hne	433	8	the	the	DT
cord-006460-3ayc0hne	433	9	Fifth	Fifth	NNP
cord-006460-3ayc0hne	433	10	World	World	NNP
cord-006460-3ayc0hne	433	11	Congress	Congress	NNP
cord-006460-3ayc0hne	433	12	on	on	IN
cord-006460-3ayc0hne	433	13	Trauma	Trauma	NNP
cord-006460-3ayc0hne	433	14	,	,	,
cord-006460-3ayc0hne	433	15	Shock	shock	NN
cord-006460-3ayc0hne	433	16	,	,	,
cord-006460-3ayc0hne	433	17	Inflammation	inflammation	NN
cord-006460-3ayc0hne	433	18	and	and	CC
cord-006460-3ayc0hne	433	19	Sepsis	sepsis	NN
cord-006460-3ayc0hne	433	20	took	take	VBD
cord-006460-3ayc0hne	433	21	place	place	NN
cord-006460-3ayc0hne	433	22	at	at	IN
cord-006460-3ayc0hne	433	23	the	the	DT
cord-006460-3ayc0hne	433	24	Klinikum	Klinikum	NNP
cord-006460-3ayc0hne	433	25	Grosshadern	Grosshadern	NNP
cord-006460-3ayc0hne	433	26	,	,	,
cord-006460-3ayc0hne	433	27	the	the	DT
cord-006460-3ayc0hne	433	28	Ludwig	Ludwig	NNP
cord-006460-3ayc0hne	433	29	Maximillians	Maximillians	NNP
cord-006460-3ayc0hne	433	30	Universität	Universität	NNP
cord-006460-3ayc0hne	433	31	,	,	,
cord-006460-3ayc0hne	433	32	Munich	Munich	NNP
cord-006460-3ayc0hne	433	33	,	,	,
cord-006460-3ayc0hne	433	34	hosted	host	VBN
cord-006460-3ayc0hne	433	35	by	by	IN
cord-006460-3ayc0hne	433	36	Professor	Professor	NNP
cord-006460-3ayc0hne	433	37	Eugen	Eugen	NNP
cord-006460-3ayc0hne	433	38	Faist	Faist	NNP
cord-006460-3ayc0hne	433	39	and	and	CC
cord-006460-3ayc0hne	433	40	Professor	Professor	NNP
cord-006460-3ayc0hne	433	41	Wilhelm	Wilhelm	NNP
cord-006460-3ayc0hne	433	42	Schildberg	Schildberg	NNP
cord-006460-3ayc0hne	433	43	.	.	.
cord-006460-3ayc0hne	434	1	Thousands	thousand	NNS
cord-006460-3ayc0hne	434	2	attended	attend	VBD
cord-006460-3ayc0hne	434	3	from	from	IN
cord-006460-3ayc0hne	434	4	more	more	JJR
cord-006460-3ayc0hne	434	5	than	than	IN
cord-006460-3ayc0hne	434	6	60	60	CD
cord-006460-3ayc0hne	434	7	countries	country	NNS
cord-006460-3ayc0hne	434	8	all	all	RB
cord-006460-3ayc0hne	434	9	over	over	IN
cord-006460-3ayc0hne	434	10	the	the	DT
cord-006460-3ayc0hne	434	11	world	world	NN
cord-006460-3ayc0hne	434	12	.	.	.
cord-006460-3ayc0hne	435	1	I	-PRON-	PRP
cord-006460-3ayc0hne	435	2	suggest	suggest	VBP
cord-006460-3ayc0hne	435	3	to	to	IN
cord-006460-3ayc0hne	435	4	you	-PRON-	PRP
cord-006460-3ayc0hne	435	5	that	that	IN
cord-006460-3ayc0hne	435	6	a	a	DT
cord-006460-3ayc0hne	435	7	major	major	JJ
cord-006460-3ayc0hne	435	8	theme	theme	NN
cord-006460-3ayc0hne	435	9	of	of	IN
cord-006460-3ayc0hne	435	10	this	this	DT
cord-006460-3ayc0hne	435	11	congress	congress	NN
cord-006460-3ayc0hne	435	12	,	,	,
cord-006460-3ayc0hne	435	13	although	although	IN
cord-006460-3ayc0hne	435	14	not	not	RB
cord-006460-3ayc0hne	435	15	stated	state	VBN
cord-006460-3ayc0hne	435	16	,	,	,
cord-006460-3ayc0hne	435	17	was	be	VBD
cord-006460-3ayc0hne	435	18	the	the	DT
cord-006460-3ayc0hne	435	19	theme	theme	NN
cord-006460-3ayc0hne	435	20	of	of	IN
cord-006460-3ayc0hne	435	21	this	this	DT
cord-006460-3ayc0hne	435	22	presentation	presentation	NN
cord-006460-3ayc0hne	435	23	-the	-the	DT
cord-006460-3ayc0hne	435	24	discrepancy	discrepancy	NN
cord-006460-3ayc0hne	435	25	between	between	IN
cord-006460-3ayc0hne	435	26	understanding	understanding	NN
cord-006460-3ayc0hne	435	27	and	and	CC
cord-006460-3ayc0hne	435	28	management	management	NN
cord-006460-3ayc0hne	435	29	.	.	.
cord-006460-3ayc0hne	436	1	At	at	IN
cord-006460-3ayc0hne	436	2	this	this	DT
cord-006460-3ayc0hne	436	3	meeting	meeting	NN
cord-006460-3ayc0hne	436	4	,	,	,
cord-006460-3ayc0hne	436	5	basic	basic	JJ
cord-006460-3ayc0hne	436	6	scientists	scientist	NNS
cord-006460-3ayc0hne	436	7	presented	present	VBD
cord-006460-3ayc0hne	436	8	the	the	DT
cord-006460-3ayc0hne	436	9	results	result	NNS
cord-006460-3ayc0hne	436	10	of	of	IN
cord-006460-3ayc0hne	436	11	their	-PRON-	PRP$
cord-006460-3ayc0hne	436	12	exciting	exciting	JJ
cord-006460-3ayc0hne	436	13	research	research	NN
cord-006460-3ayc0hne	436	14	into	into	IN
cord-006460-3ayc0hne	436	15	molecular	molecular	JJ
cord-006460-3ayc0hne	436	16	biology	biology	NN
cord-006460-3ayc0hne	436	17	on	on	IN
cord-006460-3ayc0hne	436	18	the	the	DT
cord-006460-3ayc0hne	436	19	leading	leading	JJ
cord-006460-3ayc0hne	436	20	edge	edge	NN
cord-006460-3ayc0hne	436	21	of	of	IN
cord-006460-3ayc0hne	436	22	scientific	scientific	JJ
cord-006460-3ayc0hne	436	23	knowledge	knowledge	NN
cord-006460-3ayc0hne	436	24	.	.	.
cord-006460-3ayc0hne	437	1	Clinical	clinical	JJ
cord-006460-3ayc0hne	437	2	investigators	investigator	NNS
cord-006460-3ayc0hne	437	3	presented	present	VBD
cord-006460-3ayc0hne	437	4	their	-PRON-	PRP$
cord-006460-3ayc0hne	437	5	equally	equally	RB
cord-006460-3ayc0hne	437	6	exciting	exciting	JJ
cord-006460-3ayc0hne	437	7	findings	finding	NNS
cord-006460-3ayc0hne	437	8	about	about	IN
cord-006460-3ayc0hne	437	9	sick	sick	JJ
cord-006460-3ayc0hne	437	10	,	,	,
cord-006460-3ayc0hne	437	11	injured	injured	JJ
cord-006460-3ayc0hne	437	12	and	and	CC
cord-006460-3ayc0hne	437	13	septic	septic	JJ
cord-006460-3ayc0hne	437	14	patients	patient	NNS
cord-006460-3ayc0hne	437	15	.	.	.
cord-006460-3ayc0hne	438	1	Some	some	DT
cord-006460-3ayc0hne	438	2	of	of	IN
cord-006460-3ayc0hne	438	3	the	the	DT
cord-006460-3ayc0hne	438	4	experiences	experience	NNS
cord-006460-3ayc0hne	438	5	presented	present	VBN
cord-006460-3ayc0hne	438	6	will	will	MD
cord-006460-3ayc0hne	438	7	help	help	VB
cord-006460-3ayc0hne	438	8	us	-PRON-	PRP
cord-006460-3ayc0hne	438	9	to	to	TO
cord-006460-3ayc0hne	438	10	take	take	VB
cord-006460-3ayc0hne	438	11	better	well	JJR
cord-006460-3ayc0hne	438	12	care	care	NN
cord-006460-3ayc0hne	438	13	of	of	IN
cord-006460-3ayc0hne	438	14	our	-PRON-	PRP$
cord-006460-3ayc0hne	438	15	patients	patient	NNS
cord-006460-3ayc0hne	438	16	.	.	.
cord-006460-3ayc0hne	439	1	All	all	DT
cord-006460-3ayc0hne	439	2	of	of	IN
cord-006460-3ayc0hne	439	3	these	these	DT
cord-006460-3ayc0hne	439	4	studies	study	NNS
cord-006460-3ayc0hne	439	5	are	be	VBP
cord-006460-3ayc0hne	439	6	very	very	RB
cord-006460-3ayc0hne	439	7	worthwhile	worthwhile	JJ
cord-006460-3ayc0hne	439	8	;	;	:
cord-006460-3ayc0hne	439	9	however	however	RB
cord-006460-3ayc0hne	439	10	,	,	,
cord-006460-3ayc0hne	439	11	there	there	EX
cord-006460-3ayc0hne	439	12	is	be	VBZ
cord-006460-3ayc0hne	439	13	a	a	DT
cord-006460-3ayc0hne	439	14	widening	widen	VBG
cord-006460-3ayc0hne	439	15	gap	gap	NN
cord-006460-3ayc0hne	439	16	between	between	IN
cord-006460-3ayc0hne	439	17	our	-PRON-	PRP$
cord-006460-3ayc0hne	439	18	knowledge	knowledge	NN
cord-006460-3ayc0hne	439	19	of	of	IN
cord-006460-3ayc0hne	439	20	human	human	JJ
cord-006460-3ayc0hne	439	21	biology	biology	NN
cord-006460-3ayc0hne	439	22	,	,	,
cord-006460-3ayc0hne	439	23	our	-PRON-	PRP$
cord-006460-3ayc0hne	439	24	understanding	understanding	NN
cord-006460-3ayc0hne	439	25	of	of	IN
cord-006460-3ayc0hne	439	26	it	-PRON-	PRP
cord-006460-3ayc0hne	439	27	,	,	,
cord-006460-3ayc0hne	439	28	and	and	CC
cord-006460-3ayc0hne	439	29	our	-PRON-	PRP$
cord-006460-3ayc0hne	439	30	ability	ability	NN
cord-006460-3ayc0hne	439	31	to	to	TO
cord-006460-3ayc0hne	439	32	help	help	VB
cord-006460-3ayc0hne	439	33	patients	patient	NNS
cord-006460-3ayc0hne	439	34	.	.	.
cord-006460-3ayc0hne	440	1	Why	why	WRB
cord-006460-3ayc0hne	440	2	is	be	VBZ
cord-006460-3ayc0hne	440	3	this	this	DT
cord-006460-3ayc0hne	440	4	?	?	.
cord-006460-3ayc0hne	441	1	1	1	CD
cord-006460-3ayc0hne	441	2	449	449	CD
cord-006460-3ayc0hne	441	3	Nitric	nitric	NN
cord-006460-3ayc0hne	441	4	oxide	oxide	NN
cord-006460-3ayc0hne	441	5	leads	lead	VBZ
cord-006460-3ayc0hne	441	6	to	to	IN
cord-006460-3ayc0hne	441	7	prized	prize	VBN
cord-006460-3ayc0hne	441	8	nobility	nobility	NN
cord-006460-3ayc0hne	441	9	Prolonged	prolong	VBN
cord-006460-3ayc0hne	441	10	inhibition	inhibition	NN
cord-006460-3ayc0hne	441	11	of	of	IN
cord-006460-3ayc0hne	441	12	nitric	nitric	JJ
cord-006460-3ayc0hne	441	13	oxide	oxide	NN
cord-006460-3ayc0hne	441	14	synthesis	synthesis	NN
cord-006460-3ayc0hne	441	15	in	in	IN
cord-006460-3ayc0hne	441	16	severe	severe	JJ
cord-006460-3ayc0hne	441	17	septic	septic	JJ
cord-006460-3ayc0hne	441	18	shock	shock	NN
cord-006460-3ayc0hne	441	19	:	:	:
cord-006460-3ayc0hne	441	20	a	a	DT
cord-006460-3ayc0hne	441	21	clinical	clinical	JJ
cord-006460-3ayc0hne	441	22	study	study	NN
cord-006460-3ayc0hne	441	23	Effect	effect	NN
cord-006460-3ayc0hne	441	24	of	of	IN
cord-006460-3ayc0hne	441	25	nitric	nitric	JJ
cord-006460-3ayc0hne	441	26	oxide	oxide	NN
cord-006460-3ayc0hne	441	27	synthase	synthase	NN
cord-006460-3ayc0hne	441	28	inhibitors	inhibitor	NNS
cord-006460-3ayc0hne	441	29	on	on	IN
cord-006460-3ayc0hne	441	30	hypotension	hypotension	NN
cord-006460-3ayc0hne	441	31	in	in	IN
cord-006460-3ayc0hne	441	32	patients	patient	NNS
cord-006460-3ayc0hne	441	33	with	with	IN
cord-006460-3ayc0hne	441	34	septic	septic	JJ
cord-006460-3ayc0hne	441	35	shock	shock	NN
cord-006460-3ayc0hne	442	1	Multicenter	multicenter	JJ
cord-006460-3ayc0hne	442	2	,	,	,
cord-006460-3ayc0hne	442	3	randomized	randomized	JJ
cord-006460-3ayc0hne	442	4	placebo	placebo	NN
cord-006460-3ayc0hne	442	5	-	-	HYPH
cord-006460-3ayc0hne	442	6	controlled	control	VBN
cord-006460-3ayc0hne	442	7	,	,	,
cord-006460-3ayc0hne	442	8	double	double	JJ
cord-006460-3ayc0hne	442	9	-	-	HYPH
cord-006460-3ayc0hne	442	10	blind	blind	JJ
cord-006460-3ayc0hne	442	11	study	study	NN
cord-006460-3ayc0hne	442	12	of	of	IN
cord-006460-3ayc0hne	442	13	the	the	DT
cord-006460-3ayc0hne	442	14	nitric	nitric	NN
cord-006460-3ayc0hne	442	15	oxide	oxide	NN
cord-006460-3ayc0hne	442	16	synthase	synthase	NN
cord-006460-3ayc0hne	442	17	inhibitor	inhibitor	NN
cord-006460-3ayc0hne	442	18	546C88	546c88	CD
cord-006460-3ayc0hne	443	1	The	the	DT
cord-006460-3ayc0hne	443	2	endless	endless	JJ
cord-006460-3ayc0hne	443	3	pathways	pathway	NNS
cord-006460-3ayc0hne	443	4	of	of	IN
cord-006460-3ayc0hne	443	5	discovery	discovery	NN
cord-006460-3ayc0hne	444	1	The	the	DT
cord-006460-3ayc0hne	444	2	Principles	Principles	NNPS
cord-006460-3ayc0hne	444	3	and	and	CC
cord-006460-3ayc0hne	444	4	Practice	Practice	NNP
cord-006460-3ayc0hne	444	5	of	of	IN
cord-006460-3ayc0hne	444	6	Medicine	Medicine	NNP
cord-006460-3ayc0hne	444	7	Association	Association	NNP
cord-006460-3ayc0hne	444	8	of	of	IN
cord-006460-3ayc0hne	444	9	tumor	tumor	NN
cord-006460-3ayc0hne	444	10	necrosis	necrosis	NN
cord-006460-3ayc0hne	444	11	factor	factor	NN
cord-006460-3ayc0hne	444	12	microsatellites	microsatellite	NNS
cord-006460-3ayc0hne	444	13	with	with	IN
cord-006460-3ayc0hne	444	14	incidence	incidence	NN
cord-006460-3ayc0hne	444	15	and	and	CC
cord-006460-3ayc0hne	444	16	outcome	outcome	NN
cord-006460-3ayc0hne	444	17	of	of	IN
cord-006460-3ayc0hne	444	18	severe	severe	JJ
cord-006460-3ayc0hne	444	19	sepsis	sepsis	NN
cord-006460-3ayc0hne	444	20	Multiple	multiple	JJ
cord-006460-3ayc0hne	444	21	,	,	,
cord-006460-3ayc0hne	444	22	progressive	progressive	JJ
cord-006460-3ayc0hne	444	23	or	or	CC
cord-006460-3ayc0hne	444	24	sequential	sequential	JJ
cord-006460-3ayc0hne	444	25	systems	system	NNS
cord-006460-3ayc0hne	444	26	failure	failure	NN
cord-006460-3ayc0hne	444	27	:	:	:
cord-006460-3ayc0hne	444	28	a	a	DT
cord-006460-3ayc0hne	444	29	syndrome	syndrome	NN
cord-006460-3ayc0hne	444	30	of	of	IN
cord-006460-3ayc0hne	444	31	the	the	DT
cord-006460-3ayc0hne	444	32	1970s	1970	NNS
cord-006460-3ayc0hne	444	33	Multiple	multiple	JJ
cord-006460-3ayc0hne	444	34	organ	organ	NN
cord-006460-3ayc0hne	444	35	failure	failure	NN
cord-006460-3ayc0hne	444	36	in	in	IN
cord-006460-3ayc0hne	444	37	polytrauma	polytrauma	NNP
cord-006460-3ayc0hne	444	38	patients	patient	NNS
cord-006460-3ayc0hne	445	1	Multiple	multiple	JJ
cord-006460-3ayc0hne	445	2	organ	organ	NN
cord-006460-3ayc0hne	445	3	failure	failure	NN
cord-006460-3ayc0hne	445	4	:	:	:
cord-006460-3ayc0hne	446	1	the	the	DT
cord-006460-3ayc0hne	446	2	pilgrim	pilgrim	NNP
cord-006460-3ayc0hne	446	3	's	's	POS
cord-006460-3ayc0hne	446	4	progress	progress	NN
cord-006460-3ayc0hne	446	5	The	the	DT
cord-006460-3ayc0hne	446	6	role	role	NN
cord-006460-3ayc0hne	446	7	of	of	IN
cord-006460-3ayc0hne	446	8	the	the	DT
cord-006460-3ayc0hne	446	9	gut	gut	NN
cord-006460-3ayc0hne	446	10	in	in	IN
cord-006460-3ayc0hne	446	11	the	the	DT
cord-006460-3ayc0hne	446	12	development	development	NN
cord-006460-3ayc0hne	446	13	of	of	IN
cord-006460-3ayc0hne	446	14	multiple	multiple	JJ
cord-006460-3ayc0hne	446	15	organ	organ	NN
cord-006460-3ayc0hne	446	16	dysfunction	dysfunction	NN
cord-006460-3ayc0hne	446	17	in	in	IN
cord-006460-3ayc0hne	446	18	cardiothoracic	cardiothoracic	JJ
cord-006460-3ayc0hne	446	19	patients	patient	NNS
cord-006460-3ayc0hne	446	20	Definitions	definition	NNS
cord-006460-3ayc0hne	446	21	for	for	IN
cord-006460-3ayc0hne	446	22	sepsis	sepsis	NN
cord-006460-3ayc0hne	446	23	and	and	CC
cord-006460-3ayc0hne	446	24	organ	organ	NN
cord-006460-3ayc0hne	446	25	failure	failure	NN
cord-006460-3ayc0hne	446	26	and	and	CC
cord-006460-3ayc0hne	446	27	guidelines	guideline	NNS
cord-006460-3ayc0hne	446	28	for	for	IN
cord-006460-3ayc0hne	446	29	the	the	DT
cord-006460-3ayc0hne	446	30	use	use	NN
cord-006460-3ayc0hne	446	31	of	of	IN
cord-006460-3ayc0hne	446	32	innovative	innovative	JJ
cord-006460-3ayc0hne	446	33	therapies	therapy	NNS
cord-006460-3ayc0hne	446	34	in	in	IN
cord-006460-3ayc0hne	446	35	sepsis	sepsis	NN
cord-006460-3ayc0hne	447	1	MODS	MODS	NNP
cord-006460-3ayc0hne	447	2	/	/	SYM
cord-006460-3ayc0hne	447	3	SIRS	SIRS	NNP
cord-006460-3ayc0hne	447	4	:	:	:
cord-006460-3ayc0hne	447	5	result	result	NN
cord-006460-3ayc0hne	447	6	of	of	IN
cord-006460-3ayc0hne	447	7	an	an	DT
cord-006460-3ayc0hne	447	8	overwhelming	overwhelming	JJ
cord-006460-3ayc0hne	447	9	inflammatory	inflammatory	JJ
cord-006460-3ayc0hne	447	10	response	response	NN
cord-006460-3ayc0hne	447	11	To	to	IN
cord-006460-3ayc0hne	447	12	SIRS	SIRS	NNP
cord-006460-3ayc0hne	447	13	with	with	IN
cord-006460-3ayc0hne	447	14	love	love	NN
cord-006460-3ayc0hne	448	1	Dear	dear	JJ
cord-006460-3ayc0hne	448	2	SIRS	sirs	UH
cord-006460-3ayc0hne	448	3	,	,	,
cord-006460-3ayc0hne	448	4	I	-PRON-	PRP
cord-006460-3ayc0hne	448	5	'm	be	VBP
cord-006460-3ayc0hne	448	6	sorry	sorry	JJ
cord-006460-3ayc0hne	448	7	to	to	TO
cord-006460-3ayc0hne	448	8	say	say	VB
cord-006460-3ayc0hne	448	9	I	-PRON-	PRP
cord-006460-3ayc0hne	448	10	do	do	VBP
cord-006460-3ayc0hne	448	11	n't	not	RB
cord-006460-3ayc0hne	448	12	like	like	VB
cord-006460-3ayc0hne	448	13	you	-PRON-	PRP
cord-006460-3ayc0hne	449	1	What	what	WP
cord-006460-3ayc0hne	449	2	's	be	VBZ
cord-006460-3ayc0hne	449	3	in	in	IN
cord-006460-3ayc0hne	449	4	a	a	DT
cord-006460-3ayc0hne	449	5	name	name	NN
cord-006460-3ayc0hne	449	6	?	?	.
cord-006460-3ayc0hne	450	1	An	an	DT
cord-006460-3ayc0hne	450	2	acronym	acronym	NN
cord-006460-3ayc0hne	450	3	or	or	CC
cord-006460-3ayc0hne	450	4	a	a	DT
cord-006460-3ayc0hne	450	5	response	response	NN
cord-006460-3ayc0hne	450	6	?	?	.
cord-006460-3ayc0hne	451	1	The	the	DT
cord-006460-3ayc0hne	451	2	systemic	systemic	JJ
cord-006460-3ayc0hne	451	3	inflammatory	inflammatory	JJ
cord-006460-3ayc0hne	451	4	response	response	NN
cord-006460-3ayc0hne	451	5	syndrome	syndrome	NN
cord-006460-3ayc0hne	451	6	as	as	IN
cord-006460-3ayc0hne	451	7	a	a	DT
cord-006460-3ayc0hne	451	8	predictor	predictor	NN
cord-006460-3ayc0hne	451	9	of	of	IN
cord-006460-3ayc0hne	451	10	bacteraemia	bacteraemia	NN
cord-006460-3ayc0hne	451	11	and	and	CC
cord-006460-3ayc0hne	451	12	outcome	outcome	NN
cord-006460-3ayc0hne	451	13	from	from	IN
cord-006460-3ayc0hne	451	14	sepsis	sepsis	NN
cord-006460-3ayc0hne	451	15	Blakiston	Blakiston	NNP
cord-006460-3ayc0hne	451	16	's	's	POS
cord-006460-3ayc0hne	451	17	Gould	Gould	NNP
cord-006460-3ayc0hne	451	18	Medical	Medical	NNP
cord-006460-3ayc0hne	451	19	Dictionary	Dictionary	NNP
cord-006460-3ayc0hne	451	20	(	(	-LRB-
cord-006460-3ayc0hne	451	21	1972	1972	CD
cord-006460-3ayc0hne	451	22	)	)	-RRB-
cord-006460-3ayc0hne	452	1	Blakiston	Blakiston	NNP
cord-006460-3ayc0hne	452	2	's	's	POS
cord-006460-3ayc0hne	452	3	Gould	Gould	NNP
cord-006460-3ayc0hne	452	4	medical	medical	JJ
cord-006460-3ayc0hne	452	5	dictionary	dictionary	NN
cord-006460-3ayc0hne	452	6	SIRS	sirs	UH
cord-006460-3ayc0hne	452	7	,	,	,
cord-006460-3ayc0hne	452	8	MODS	MODS	NNP
cord-006460-3ayc0hne	452	9	,	,	,
cord-006460-3ayc0hne	452	10	MOFwhat	MOFwhat	NNP
cord-006460-3ayc0hne	452	11	's	be	VBZ
cord-006460-3ayc0hne	452	12	in	in	IN
cord-006460-3ayc0hne	452	13	a	a	DT
cord-006460-3ayc0hne	452	14	name	name	NN
cord-006460-3ayc0hne	452	15	?	?	.
cord-006460-3ayc0hne	453	1	Multiple	multiple	JJ
cord-006460-3ayc0hne	453	2	organ	organ	NN
cord-006460-3ayc0hne	453	3	failure	failure	NN
cord-006460-3ayc0hne	453	4	:	:	:
cord-006460-3ayc0hne	453	5	generalized	generalized	JJ
cord-006460-3ayc0hne	453	6	and	and	CC
cord-006460-3ayc0hne	453	7	destructive	destructive	JJ
cord-006460-3ayc0hne	453	8	inflammation	inflammation	NN
cord-006460-3ayc0hne	453	9	Treatise	treatise	NN
cord-006460-3ayc0hne	453	10	on	on	IN
cord-006460-3ayc0hne	453	11	the	the	DT
cord-006460-3ayc0hne	453	12	Blood	blood	NN
cord-006460-3ayc0hne	453	13	Inflammation	inflammation	NN
cord-006460-3ayc0hne	453	14	and	and	CC
cord-006460-3ayc0hne	453	15	Gunshot	gunshot	NN
cord-006460-3ayc0hne	453	16	Wounds	Wounds	NNPS
cord-006460-3ayc0hne	453	17	Ueber	Ueber	NNP
cord-006460-3ayc0hne	453	18	Hämolysins	Hämolysins	NNP
cord-006460-3ayc0hne	453	19	.	.	.
cord-006460-3ayc0hne	454	1	Fünfte	Fünfte	NNP
cord-006460-3ayc0hne	454	2	Mittei	Mittei	NNP
cord-006460-3ayc0hne	454	3	lung	lung	NN
cord-006460-3ayc0hne	454	4	Clinical	clinical	JJ
cord-006460-3ayc0hne	454	5	trials	trial	NNS
cord-006460-3ayc0hne	454	6	for	for	IN
cord-006460-3ayc0hne	454	7	severe	severe	JJ
cord-006460-3ayc0hne	454	8	sepsis	sepsis	NN
cord-006460-3ayc0hne	454	9	:	:	:
cord-006460-3ayc0hne	455	1	past	past	JJ
cord-006460-3ayc0hne	455	2	failures	failure	NNS
cord-006460-3ayc0hne	455	3	and	and	CC
cord-006460-3ayc0hne	455	4	future	future	JJ
cord-006460-3ayc0hne	455	5	hopes	hope	NNS
cord-006460-3ayc0hne	456	1	Why	why	WRB
cord-006460-3ayc0hne	456	2	have	have	VBP
cord-006460-3ayc0hne	456	3	new	new	JJ
cord-006460-3ayc0hne	456	4	effective	effective	JJ
cord-006460-3ayc0hne	456	5	therapies	therapy	NNS
cord-006460-3ayc0hne	456	6	for	for	IN
cord-006460-3ayc0hne	456	7	sepsis	sepsis	NN
cord-006460-3ayc0hne	456	8	not	not	RB
cord-006460-3ayc0hne	456	9	been	be	VBN
cord-006460-3ayc0hne	456	10	developed	develop	VBN
cord-006460-3ayc0hne	456	11	?	?	.
cord-006460-3ayc0hne	457	1	Why	why	WRB
cord-006460-3ayc0hne	457	2	sepsis	sepsis	NN
cord-006460-3ayc0hne	457	3	trials	trial	NNS
cord-006460-3ayc0hne	457	4	fail	fail	VBP
cord-006460-3ayc0hne	457	5	Anti	anti	JJ
cord-006460-3ayc0hne	457	6	-	-	JJ
cord-006460-3ayc0hne	457	7	inflammatory	inflammatory	JJ
cord-006460-3ayc0hne	457	8	therapies	therapy	NNS
cord-006460-3ayc0hne	457	9	to	to	TO
cord-006460-3ayc0hne	457	10	treat	treat	VB
cord-006460-3ayc0hne	457	11	sepsis	sepsis	NN
cord-006460-3ayc0hne	457	12	and	and	CC
cord-006460-3ayc0hne	457	13	septic	septic	JJ
cord-006460-3ayc0hne	457	14	shock	shock	NN
cord-006460-3ayc0hne	457	15	:	:	:
cord-006460-3ayc0hne	457	16	a	a	DT
cord-006460-3ayc0hne	457	17	reassessment	reassessment	NN
cord-006460-3ayc0hne	457	18	MOF	MOF	NNP
cord-006460-3ayc0hne	457	19	,	,	,
cord-006460-3ayc0hne	457	20	MODS	MODS	NNP
cord-006460-3ayc0hne	457	21	and	and	CC
cord-006460-3ayc0hne	457	22	SIRS	sir	NNS
cord-006460-3ayc0hne	457	23	-why	-why	:
cord-006460-3ayc0hne	457	24	no	no	DT
cord-006460-3ayc0hne	457	25	magic	magic	JJ
cord-006460-3ayc0hne	457	26	bullets	bullet	NNS
cord-006460-3ayc0hne	457	27	?	?	.
cord-006460-3ayc0hne	458	1	Blood	blood	NN
cord-006460-3ayc0hne	458	2	substitutes	substitute	NNS
cord-006460-3ayc0hne	458	3	N	n	CD
cord-006460-3ayc0hne	458	4	-	-	HYPH
cord-006460-3ayc0hne	458	5	acetylcysteine	acetylcysteine	NN
cord-006460-3ayc0hne	458	6	enhances	enhance	VBZ
cord-006460-3ayc0hne	458	7	recovery	recovery	NN
cord-006460-3ayc0hne	458	8	from	from	IN
cord-006460-3ayc0hne	458	9	acute	acute	JJ
cord-006460-3ayc0hne	458	10	lung	lung	NN
cord-006460-3ayc0hne	458	11	injury	injury	NN
cord-006460-3ayc0hne	458	12	in	in	IN
cord-006460-3ayc0hne	458	13	man	man	NN
cord-006460-3ayc0hne	458	14	:	:	:
cord-006460-3ayc0hne	458	15	a	a	DT
cord-006460-3ayc0hne	458	16	randomized	randomized	JJ
cord-006460-3ayc0hne	458	17	,	,	,
cord-006460-3ayc0hne	458	18	double	double	JJ
cord-006460-3ayc0hne	458	19	-	-	HYPH
cord-006460-3ayc0hne	458	20	blind	blind	JJ
cord-006460-3ayc0hne	458	21	,	,	,
cord-006460-3ayc0hne	458	22	placebo	placebo	NN
cord-006460-3ayc0hne	458	23	-	-	HYPH
cord-006460-3ayc0hne	458	24	controlled	control	VBN
cord-006460-3ayc0hne	458	25	clinical	clinical	JJ
cord-006460-3ayc0hne	458	26	study	study	NN
cord-006460-3ayc0hne	458	27	Tracing	trace	VBG
cord-006460-3ayc0hne	458	28	leptins	leptins	NNP
cord-006460-3ayc0hne	458	29	partners	partner	NNS
cord-006460-3ayc0hne	458	30	in	in	IN
cord-006460-3ayc0hne	458	31	regulating	regulate	VBG
cord-006460-3ayc0hne	458	32	body	body	NN
cord-006460-3ayc0hne	458	33	weight	weight	NN
cord-006460-3ayc0hne	458	34	Swindell	Swindell	NNP
cord-006460-3ayc0hne	458	35	BB	BB	NNP
cord-006460-3ayc0hne	458	36	(	(	-LRB-
cord-006460-3ayc0hne	458	37	1997	1997	CD
cord-006460-3ayc0hne	458	38	)	)	-RRB-
cord-006460-3ayc0hne	459	1	The	the	DT
cord-006460-3ayc0hne	459	2	effects	effect	NNS
cord-006460-3ayc0hne	459	3	of	of	IN
cord-006460-3ayc0hne	459	4	ibuprofen	ibuprofen	NN
cord-006460-3ayc0hne	459	5	on	on	IN
cord-006460-3ayc0hne	459	6	the	the	DT
cord-006460-3ayc0hne	459	7	physiology	physiology	NN
cord-006460-3ayc0hne	459	8	and	and	CC
cord-006460-3ayc0hne	459	9	survival	survival	NN
cord-006460-3ayc0hne	459	10	of	of	IN
cord-006460-3ayc0hne	459	11	patients	patient	NNS
cord-006460-3ayc0hne	459	12	with	with	IN
cord-006460-3ayc0hne	459	13	sepsis	sepsis	NN
cord-006460-3ayc0hne	459	14	High	high	JJ
cord-006460-3ayc0hne	459	15	-	-	HYPH
cord-006460-3ayc0hne	459	16	dose	dose	NN
cord-006460-3ayc0hne	459	17	antithrombin	antithrombin	NN
cord-006460-3ayc0hne	459	18	III	iii	CD
cord-006460-3ayc0hne	459	19	treatment	treatment	NN
cord-006460-3ayc0hne	459	20	of	of	IN
cord-006460-3ayc0hne	459	21	severely	severely	RB
cord-006460-3ayc0hne	459	22	injured	injure	VBN
cord-006460-3ayc0hne	459	23	patients	patient	NNS
cord-006460-3ayc0hne	459	24	:	:	:
cord-006460-3ayc0hne	459	25	results	result	NNS
cord-006460-3ayc0hne	459	26	of	of	IN
cord-006460-3ayc0hne	459	27	a	a	DT
cord-006460-3ayc0hne	459	28	prospective	prospective	JJ
cord-006460-3ayc0hne	459	29	study	study	NN
cord-006460-3ayc0hne	459	30	Phase	Phase	NNP
cord-006460-3ayc0hne	459	31	II	ii	CD
cord-006460-3ayc0hne	459	32	multicenter	multicenter	JJ
cord-006460-3ayc0hne	459	33	clinical	clinical	JJ
cord-006460-3ayc0hne	459	34	study	study	NN
cord-006460-3ayc0hne	459	35	of	of	IN
cord-006460-3ayc0hne	459	36	the	the	DT
cord-006460-3ayc0hne	459	37	platelet	platelet	NN
cord-006460-3ayc0hne	459	38	-	-	HYPH
cord-006460-3ayc0hne	459	39	activating	activate	VBG
cord-006460-3ayc0hne	459	40	factor	factor	NN
cord-006460-3ayc0hne	459	41	receptor	receptor	NN
cord-006460-3ayc0hne	459	42	antagonist	antagonist	NN
cord-006460-3ayc0hne	460	1	BB-882	bb-882	NN
cord-006460-3ayc0hne	460	2	in	in	IN
cord-006460-3ayc0hne	460	3	the	the	DT
cord-006460-3ayc0hne	460	4	treatment	treatment	NN
cord-006460-3ayc0hne	460	5	of	of	IN
cord-006460-3ayc0hne	460	6	sepsis	sepsis	NN
cord-006460-3ayc0hne	460	7	Treatment	treatment	NN
cord-006460-3ayc0hne	460	8	of	of	IN
cord-006460-3ayc0hne	460	9	patients	patient	NNS
cord-006460-3ayc0hne	460	10	with	with	IN
cord-006460-3ayc0hne	460	11	sepsis	sepsis	NN
cord-006460-3ayc0hne	460	12	syndrome	syndrome	NN
cord-006460-3ayc0hne	460	13	with	with	IN
cord-006460-3ayc0hne	460	14	soluble	soluble	JJ
cord-006460-3ayc0hne	460	15	TNF	TNF	NNP
cord-006460-3ayc0hne	460	16	receptor	receptor	NN
cord-006460-3ayc0hne	460	17	(	(	-LRB-
cord-006460-3ayc0hne	460	18	sTNFr	stnfr	ADD
cord-006460-3ayc0hne	460	19	)	)	-RRB-
cord-006460-3ayc0hne	461	1	Investigations	investigation	NNS
cord-006460-3ayc0hne	461	2	into	into	IN
cord-006460-3ayc0hne	461	3	the	the	DT
cord-006460-3ayc0hne	461	4	polydeterminant	polydeterminant	JJ
cord-006460-3ayc0hne	461	5	nature	nature	NN
cord-006460-3ayc0hne	461	6	of	of	IN
cord-006460-3ayc0hne	461	7	sepsis	sepsis	NN
cord-006460-3ayc0hne	461	8	Causality	causality	NN
cord-006460-3ayc0hne	461	9	in	in	IN
cord-006460-3ayc0hne	461	10	medical	medical	JJ
cord-006460-3ayc0hne	461	11	science	science	NN
cord-006460-3ayc0hne	461	12	with	with	IN
cord-006460-3ayc0hne	461	13	particular	particular	JJ
cord-006460-3ayc0hne	461	14	reference	reference	NN
cord-006460-3ayc0hne	461	15	to	to	IN
cord-006460-3ayc0hne	461	16	heart	heart	NN
cord-006460-3ayc0hne	461	17	disease	disease	NN
cord-006460-3ayc0hne	461	18	and	and	CC
cord-006460-3ayc0hne	461	19	atherosclerosis	atherosclerosis	NN
cord-006460-3ayc0hne	461	20	.	.	.
cord-006460-3ayc0hne	462	1	Perspect	Perspect	NNP
cord-006460-3ayc0hne	463	1	The	the	DT
cord-006460-3ayc0hne	463	2	concept	concept	NN
cord-006460-3ayc0hne	463	3	of	of	IN
cord-006460-3ayc0hne	463	4	cause	cause	NN
cord-006460-3ayc0hne	463	5	in	in	IN
cord-006460-3ayc0hne	463	6	disease	disease	NNP
cord-006460-3ayc0hne	463	7	Consensus	Consensus	NNP
cord-006460-3ayc0hne	463	8	conference	conference	NN
cord-006460-3ayc0hne	463	9	definitions	definition	NNS
cord-006460-3ayc0hne	463	10	for	for	IN
cord-006460-3ayc0hne	463	11	sepsis	sepsis	NN
cord-006460-3ayc0hne	463	12	,	,	,
cord-006460-3ayc0hne	463	13	septic	septic	JJ
cord-006460-3ayc0hne	463	14	shock	shock	NN
cord-006460-3ayc0hne	463	15	,	,	,
cord-006460-3ayc0hne	463	16	acute	acute	JJ
cord-006460-3ayc0hne	463	17	lung	lung	NN
cord-006460-3ayc0hne	463	18	injury	injury	NN
cord-006460-3ayc0hne	463	19	,	,	,
cord-006460-3ayc0hne	463	20	and	and	CC
cord-006460-3ayc0hne	463	21	acute	acute	JJ
cord-006460-3ayc0hne	463	22	respiratory	respiratory	JJ
cord-006460-3ayc0hne	463	23	distress	distress	NN
cord-006460-3ayc0hne	463	24	syndrome	syndrome	NN
cord-006460-3ayc0hne	463	25	:	:	:
cord-006460-3ayc0hne	463	26	time	time	NN
cord-006460-3ayc0hne	463	27	for	for	IN
cord-006460-3ayc0hne	463	28	a	a	DT
cord-006460-3ayc0hne	463	29	reevaluation	reevaluation	NN
cord-006460-3ayc0hne	463	30	Lymphocytes	lymphocyte	NNS
cord-006460-3ayc0hne	463	31	play	play	VBP
cord-006460-3ayc0hne	463	32	the	the	DT
cord-006460-3ayc0hne	463	33	music	music	NN
cord-006460-3ayc0hne	463	34	but	but	CC
cord-006460-3ayc0hne	463	35	the	the	DT
cord-006460-3ayc0hne	463	36	macrophages	macrophage	NNS
cord-006460-3ayc0hne	463	37	call	call	VBP
cord-006460-3ayc0hne	463	38	the	the	DT
cord-006460-3ayc0hne	463	39	tune	tune	NN
cord-006460-3ayc0hne	463	40	Genetic	genetic	JJ
cord-006460-3ayc0hne	463	41	predisposition	predisposition	NN
cord-006460-3ayc0hne	463	42	to	to	IN
cord-006460-3ayc0hne	463	43	sepsis	sepsis	NN
cord-006460-3ayc0hne	463	44	and	and	CC
cord-006460-3ayc0hne	463	45	organ	organ	NN
cord-006460-3ayc0hne	463	46	failure	failure	NN
cord-006460-3ayc0hne	463	47	Comparison	comparison	NN
cord-006460-3ayc0hne	463	48	of	of	IN
cord-006460-3ayc0hne	463	49	two	two	CD
cord-006460-3ayc0hne	463	50	polymorphisms	polymorphism	NNS
cord-006460-3ayc0hne	463	51	of	of	IN
cord-006460-3ayc0hne	463	52	the	the	DT
cord-006460-3ayc0hne	463	53	interleukin-1	interleukin-1	NNP
cord-006460-3ayc0hne	463	54	gene	gene	NN
cord-006460-3ayc0hne	463	55	family	family	NN
cord-006460-3ayc0hne	463	56	:	:	:
cord-006460-3ayc0hne	463	57	interleukin-1	interleukin-1	NNP
cord-006460-3ayc0hne	463	58	receptor	receptor	NN
cord-006460-3ayc0hne	463	59	antagonist	antagonist	NN
cord-006460-3ayc0hne	463	60	polymorphism	polymorphism	NN
cord-006460-3ayc0hne	463	61	contributes	contribute	VBZ
cord-006460-3ayc0hne	463	62	to	to	IN
cord-006460-3ayc0hne	463	63	susceptibility	susceptibility	NN
cord-006460-3ayc0hne	463	64	to	to	IN
cord-006460-3ayc0hne	463	65	severe	severe	JJ
cord-006460-3ayc0hne	463	66	sepsis	sepsis	NN
cord-006460-3ayc0hne	464	1	Is	be	VBZ
cord-006460-3ayc0hne	464	2	there	there	EX
cord-006460-3ayc0hne	464	3	an	an	DT
cord-006460-3ayc0hne	464	4	interleukin-1	interleukin-1	NN
cord-006460-3ayc0hne	464	5	genetic	genetic	JJ
cord-006460-3ayc0hne	464	6	predisposition	predisposition	NN
cord-006460-3ayc0hne	464	7	to	to	IN
cord-006460-3ayc0hne	464	8	developing	develop	VBG
cord-006460-3ayc0hne	464	9	severe	severe	JJ
cord-006460-3ayc0hne	464	10	sepsis	sepsis	NN
cord-006460-3ayc0hne	464	11	?	?	.
cord-006460-3ayc0hne	465	1	Association	Association	NNP
cord-006460-3ayc0hne	465	2	of	of	IN
cord-006460-3ayc0hne	465	3	TNF2	TNF2	NNP
cord-006460-3ayc0hne	465	4	,	,	,
cord-006460-3ayc0hne	465	5	a	a	DT
cord-006460-3ayc0hne	465	6	TNF	TNF	NNP
cord-006460-3ayc0hne	465	7	-	-	HYPH
cord-006460-3ayc0hne	465	8	α	α	NN
cord-006460-3ayc0hne	465	9	promoter	promoter	NN
cord-006460-3ayc0hne	465	10	polymorphism	polymorphism	NN
cord-006460-3ayc0hne	465	11	,	,	,
cord-006460-3ayc0hne	465	12	with	with	IN
cord-006460-3ayc0hne	465	13	septic	septic	JJ
cord-006460-3ayc0hne	465	14	shock	shock	NN
cord-006460-3ayc0hne	465	15	susceptibility	susceptibility	NN
cord-006460-3ayc0hne	465	16	and	and	CC
cord-006460-3ayc0hne	465	17	mortality	mortality	NN
cord-006460-3ayc0hne	465	18	,	,	,
cord-006460-3ayc0hne	465	19	a	a	DT
cord-006460-3ayc0hne	465	20	multicenter	multicenter	JJ
cord-006460-3ayc0hne	465	21	study	study	NN
cord-006460-3ayc0hne	465	22	Relation	relation	NN
cord-006460-3ayc0hne	465	23	of	of	IN
cord-006460-3ayc0hne	465	24	a	a	DT
cord-006460-3ayc0hne	465	25	TNF	TNF	NNP
cord-006460-3ayc0hne	465	26	gene	gene	NN
cord-006460-3ayc0hne	465	27	polymorphism	polymorphism	NN
cord-006460-3ayc0hne	465	28	to	to	IN
cord-006460-3ayc0hne	465	29	severe	severe	JJ
cord-006460-3ayc0hne	465	30	sepsis	sepsis	NN
cord-006460-3ayc0hne	465	31	in	in	IN
cord-006460-3ayc0hne	465	32	trauma	trauma	NN
cord-006460-3ayc0hne	465	33	patients	patient	NNS
cord-006460-3ayc0hne	465	34	Relationship	relationship	NN
cord-006460-3ayc0hne	465	35	of	of	IN
cord-006460-3ayc0hne	465	36	preoperative	preoperative	JJ
cord-006460-3ayc0hne	465	37	antiendotoxin	antiendotoxin	NN
cord-006460-3ayc0hne	465	38	core	core	NN
cord-006460-3ayc0hne	465	39	antibodies	antibody	NNS
cord-006460-3ayc0hne	465	40	and	and	CC
cord-006460-3ayc0hne	465	41	adverse	adverse	JJ
cord-006460-3ayc0hne	465	42	outcomes	outcome	NNS
cord-006460-3ayc0hne	465	43	following	follow	VBG
cord-006460-3ayc0hne	465	44	cardiac	cardiac	JJ
cord-006460-3ayc0hne	465	45	surgery	surgery	NN
cord-006460-3ayc0hne	465	46	Relationship	relationship	NN
cord-006460-3ayc0hne	465	47	between	between	IN
cord-006460-3ayc0hne	465	48	preoperative	preoperative	JJ
cord-006460-3ayc0hne	465	49	endotoxin	endotoxin	NN
cord-006460-3ayc0hne	465	50	immune	immune	NN
cord-006460-3ayc0hne	465	51	status	status	NN
cord-006460-3ayc0hne	465	52	,	,	,
cord-006460-3ayc0hne	465	53	gut	gut	NN
cord-006460-3ayc0hne	465	54	perfusion	perfusion	NN
cord-006460-3ayc0hne	465	55	,	,	,
cord-006460-3ayc0hne	465	56	and	and	CC
cord-006460-3ayc0hne	465	57	outcome	outcome	NN
cord-006460-3ayc0hne	465	58	from	from	IN
cord-006460-3ayc0hne	465	59	cardiac	cardiac	JJ
cord-006460-3ayc0hne	465	60	valve	valve	NN
cord-006460-3ayc0hne	465	61	replacement	replacement	NN
cord-006460-3ayc0hne	465	62	surgery	surgery	NN
cord-006460-3ayc0hne	465	63	Hemorrhage	hemorrhage	NN
cord-006460-3ayc0hne	465	64	and	and	CC
cord-006460-3ayc0hne	465	65	resuscitation	resuscitation	NN
cord-006460-3ayc0hne	465	66	;	;	,
cord-006460-3ayc0hne	465	67	immunological	immunological	JJ
cord-006460-3ayc0hne	465	68	aspects	aspect	NNS
cord-006460-3ayc0hne	466	1	Cytokine	cytokine	NN
cord-006460-3ayc0hne	466	2	pleiotropy	pleiotropy	NN
cord-006460-3ayc0hne	466	3	and	and	CC
cord-006460-3ayc0hne	466	4	redundancy	redundancy	NN
cord-006460-3ayc0hne	467	1	-gp130	-gp130	.
cord-006460-3ayc0hne	468	1	cytokines	cytokine	NNS
cord-006460-3ayc0hne	468	2	in	in	IN
cord-006460-3ayc0hne	468	3	human	human	JJ
cord-006460-3ayc0hne	468	4	implantation	implantation	NN
cord-006460-3ayc0hne	469	1	Attenuating	attenuate	VBG
cord-006460-3ayc0hne	469	2	tumor	tumor	NN
cord-006460-3ayc0hne	469	3	necrosis	necrosis	NN
cord-006460-3ayc0hne	469	4	factor	factor	NN
cord-006460-3ayc0hne	469	5	α	α	NN
cord-006460-3ayc0hne	469	6	does	do	VBZ
cord-006460-3ayc0hne	469	7	not	not	RB
cord-006460-3ayc0hne	469	8	ameliorate	ameliorate	VB
cord-006460-3ayc0hne	469	9	other	other	JJ
cord-006460-3ayc0hne	469	10	cytokine	cytokine	NN
cord-006460-3ayc0hne	469	11	and	and	CC
cord-006460-3ayc0hne	469	12	peroxidase	peroxidase	NN
cord-006460-3ayc0hne	469	13	products	product	NNS
cord-006460-3ayc0hne	469	14	during	during	IN
cord-006460-3ayc0hne	469	15	sepsis	sepsis	NN
cord-006460-3ayc0hne	469	16	Microsatellite	Microsatellite	NNP
cord-006460-3ayc0hne	469	17	marker	marker	NN
cord-006460-3ayc0hne	469	18	of	of	IN
cord-006460-3ayc0hne	469	19	interferon	interferon	NN
cord-006460-3ayc0hne	469	20	-	-	HYPH
cord-006460-3ayc0hne	469	21	γ	γ	NN
cord-006460-3ayc0hne	469	22	receptor	receptor	NN
cord-006460-3ayc0hne	469	23	1	1	CD
cord-006460-3ayc0hne	469	24	gene	gene	NN
cord-006460-3ayc0hne	469	25	correlates	correlate	VBZ
cord-006460-3ayc0hne	469	26	with	with	IN
cord-006460-3ayc0hne	469	27	infection	infection	NN
cord-006460-3ayc0hne	469	28	following	follow	VBG
cord-006460-3ayc0hne	469	29	major	major	JJ
cord-006460-3ayc0hne	469	30	trauma	trauma	NN
cord-006460-3ayc0hne	469	31	Discordant	discordant	JJ
cord-006460-3ayc0hne	469	32	tumor	tumor	NN
cord-006460-3ayc0hne	469	33	necrosis	necrosis	NN
cord-006460-3ayc0hne	469	34	factor	factor	NN
cord-006460-3ayc0hne	469	35	-	-	HYPH
cord-006460-3ayc0hne	469	36	α	α	NNP
cord-006460-3ayc0hne	469	37	superfamily	superfamily	NN
cord-006460-3ayc0hne	469	38	gene	gene	NN
cord-006460-3ayc0hne	469	39	expression	expression	NN
cord-006460-3ayc0hne	469	40	in	in	IN
cord-006460-3ayc0hne	469	41	bacterial	bacterial	JJ
cord-006460-3ayc0hne	469	42	peritonitis	peritonitis	NN
cord-006460-3ayc0hne	469	43	and	and	CC
cord-006460-3ayc0hne	469	44	endotoxemic	endotoxemic	NNP
cord-006460-3ayc0hne	469	45	shock	shock	NN
cord-006460-3ayc0hne	469	46	Differential	differential	JJ
cord-006460-3ayc0hne	469	47	expression	expression	NN
cord-006460-3ayc0hne	469	48	of	of	IN
cord-006460-3ayc0hne	469	49	tumor	tumor	NN
cord-006460-3ayc0hne	469	50	necrosis	necrosis	NN
cord-006460-3ayc0hne	469	51	factor	factor	NN
cord-006460-3ayc0hne	469	52	receptor	receptor	NN
cord-006460-3ayc0hne	469	53	subtypes	subtype	NNS
cord-006460-3ayc0hne	469	54	on	on	IN
cord-006460-3ayc0hne	469	55	leukocytes	leukocyte	NNS
cord-006460-3ayc0hne	469	56	in	in	IN
cord-006460-3ayc0hne	469	57	systemic	systemic	JJ
cord-006460-3ayc0hne	469	58	inflammatory	inflammatory	JJ
cord-006460-3ayc0hne	469	59	response	response	NN
cord-006460-3ayc0hne	469	60	syndrome	syndrome	NN
cord-006460-3ayc0hne	469	61	Analysis	Analysis	NNP
cord-006460-3ayc0hne	469	62	of	of	IN
cord-006460-3ayc0hne	469	63	two	two	CD
cord-006460-3ayc0hne	469	64	human	human	JJ
cord-006460-3ayc0hne	469	65	leukocyte	leukocyte	NN
cord-006460-3ayc0hne	469	66	antigen	antigen	NN
cord-006460-3ayc0hne	469	67	-	-	HYPH
cord-006460-3ayc0hne	469	68	linked	link	VBN
cord-006460-3ayc0hne	469	69	polymorphic	polymorphic	JJ
cord-006460-3ayc0hne	469	70	heat	heat	NN
cord-006460-3ayc0hne	469	71	shock	shock	NN
cord-006460-3ayc0hne	469	72	protein	protein	NN
cord-006460-3ayc0hne	469	73	70	70	CD
cord-006460-3ayc0hne	469	74	genes	gene	NNS
cord-006460-3ayc0hne	469	75	in	in	IN
cord-006460-3ayc0hne	469	76	patients	patient	NNS
cord-006460-3ayc0hne	469	77	with	with	IN
cord-006460-3ayc0hne	469	78	severe	severe	JJ
cord-006460-3ayc0hne	469	79	sepsis	sepsis	NN
cord-006460-3ayc0hne	469	80	Immunological	immunological	JJ
cord-006460-3ayc0hne	469	81	and	and	CC
cord-006460-3ayc0hne	469	82	inflammatory	inflammatory	JJ
cord-006460-3ayc0hne	469	83	consequences	consequence	NNS
cord-006460-3ayc0hne	469	84	of	of	IN
cord-006460-3ayc0hne	469	85	surgical	surgical	JJ
cord-006460-3ayc0hne	469	86	trauma	trauma	NN
cord-006460-3ayc0hne	469	87	Genetic	genetic	JJ
cord-006460-3ayc0hne	469	88	component	component	NN
cord-006460-3ayc0hne	469	89	in	in	IN
cord-006460-3ayc0hne	469	90	the	the	DT
cord-006460-3ayc0hne	469	91	inflammatory	inflammatory	JJ
cord-006460-3ayc0hne	469	92	response	response	NN
cord-006460-3ayc0hne	469	93	induced	induce	VBN
cord-006460-3ayc0hne	469	94	by	by	IN
cord-006460-3ayc0hne	469	95	bacterial	bacterial	JJ
cord-006460-3ayc0hne	469	96	lipopolysaccharide	lipopolysaccharide	NN
cord-006460-3ayc0hne	469	97	Genetic	genetic	JJ
cord-006460-3ayc0hne	469	98	factors	factor	NNS
cord-006460-3ayc0hne	469	99	in	in	IN
cord-006460-3ayc0hne	469	100	septic	septic	JJ
cord-006460-3ayc0hne	469	101	shock	shock	NN
cord-006460-3ayc0hne	469	102	New	new	JJ
cord-006460-3ayc0hne	469	103	developments	development	NNS
cord-006460-3ayc0hne	469	104	in	in	IN
cord-006460-3ayc0hne	469	105	pathophysiology	pathophysiology	NN
cord-006460-3ayc0hne	469	106	of	of	IN
cord-006460-3ayc0hne	469	107	endotoxins	endotoxin	NNS
cord-006460-3ayc0hne	469	108	and	and	CC
cord-006460-3ayc0hne	469	109	opportunities	opportunity	NNS
cord-006460-3ayc0hne	469	110	for	for	IN
cord-006460-3ayc0hne	469	111	treatment	treatment	NN
cord-006460-3ayc0hne	469	112	Endotoxin	endotoxin	NN
cord-006460-3ayc0hne	469	113	,	,	,
cord-006460-3ayc0hne	469	114	sepsis	sepsis	NN
cord-006460-3ayc0hne	469	115	,	,	,
cord-006460-3ayc0hne	469	116	and	and	CC
cord-006460-3ayc0hne	469	117	the	the	DT
cord-006460-3ayc0hne	469	118	primrose	primrose	NN
cord-006460-3ayc0hne	469	119	path	path	NN
cord-006460-3ayc0hne	469	120	Chlamydia	Chlamydia	NNP
cord-006460-3ayc0hne	469	121	:	:	:
cord-006460-3ayc0hne	470	1	old	old	JJ
cord-006460-3ayc0hne	470	2	ideas	idea	NNS
cord-006460-3ayc0hne	470	3	crushed	crush	VBN
cord-006460-3ayc0hne	470	4	,	,	,
cord-006460-3ayc0hne	470	5	new	new	JJ
cord-006460-3ayc0hne	470	6	mysteries	mystery	NNS
cord-006460-3ayc0hne	470	7	bared	bare	VBD
cord-006460-3ayc0hne	470	8	Inflammation	inflammation	NN
cord-006460-3ayc0hne	470	9	,	,	,
cord-006460-3ayc0hne	470	10	infection	infection	NN
cord-006460-3ayc0hne	470	11	,	,	,
cord-006460-3ayc0hne	470	12	and	and	CC
cord-006460-3ayc0hne	470	13	coronary	coronary	JJ
cord-006460-3ayc0hne	470	14	artery	artery	NN
cord-006460-3ayc0hne	470	15	disease	disease	NN
cord-006460-3ayc0hne	470	16	Does	do	VBZ
cord-006460-3ayc0hne	470	17	Chlamydia	Chlamydia	NNP
cord-006460-3ayc0hne	470	18	pneumoniae	pneumoniae	NN
cord-006460-3ayc0hne	470	19	cause	cause	VB
cord-006460-3ayc0hne	470	20	atherosclerosis	atherosclerosis	NN
cord-006460-3ayc0hne	470	21	?	?	.
cord-006460-3ayc0hne	471	1	Helicobacter	helicobacter	NN
cord-006460-3ayc0hne	471	2	pylori	pylori	NN
cord-006460-3ayc0hne	471	3	and	and	CC
cord-006460-3ayc0hne	471	4	critical	critical	JJ
cord-006460-3ayc0hne	471	5	illness	illness	NN
cord-006460-3ayc0hne	471	6	:	:	:
cord-006460-3ayc0hne	471	7	a	a	DT
cord-006460-3ayc0hne	471	8	passive	passive	JJ
cord-006460-3ayc0hne	471	9	bystander	bystander	NN
cord-006460-3ayc0hne	471	10	or	or	CC
cord-006460-3ayc0hne	471	11	cause	cause	NN
cord-006460-3ayc0hne	471	12	of	of	IN
cord-006460-3ayc0hne	471	13	disease	disease	NN
cord-006460-3ayc0hne	471	14	?	?	.
cord-006460-3ayc0hne	472	1	Antibiotics	antibiotic	NNS
cord-006460-3ayc0hne	472	2	and	and	CC
cord-006460-3ayc0hne	472	3	risk	risk	NN
cord-006460-3ayc0hne	472	4	of	of	IN
cord-006460-3ayc0hne	472	5	subsequent	subsequent	JJ
cord-006460-3ayc0hne	472	6	first	first	JJ
cord-006460-3ayc0hne	472	7	-	-	HYPH
cord-006460-3ayc0hne	472	8	time	time	NN
cord-006460-3ayc0hne	472	9	acute	acute	JJ
cord-006460-3ayc0hne	472	10	myocardial	myocardial	JJ
cord-006460-3ayc0hne	472	11	infarction	infarction	NN
cord-006460-3ayc0hne	472	12	Gender	gender	NN
cord-006460-3ayc0hne	472	13	dimorphism	dimorphism	NN
cord-006460-3ayc0hne	472	14	in	in	IN
cord-006460-3ayc0hne	472	15	trauma	trauma	NN
cord-006460-3ayc0hne	472	16	-	-	HYPH
cord-006460-3ayc0hne	472	17	hemorrhage	hemorrhage	NN
cord-006460-3ayc0hne	472	18	-	-	HYPH
cord-006460-3ayc0hne	472	19	induced	induce	VBN
cord-006460-3ayc0hne	472	20	thymocyte	thymocyte	NN
cord-006460-3ayc0hne	472	21	apoptosis	apoptosis	NN
cord-006460-3ayc0hne	472	22	The	the	DT
cord-006460-3ayc0hne	472	23	male	male	NN
cord-006460-3ayc0hne	472	24	's	's	POS
cord-006460-3ayc0hne	472	25	dilemma	dilemma	NN
cord-006460-3ayc0hne	472	26	Gender	gender	NN
cord-006460-3ayc0hne	472	27	-	-	HYPH
cord-006460-3ayc0hne	472	28	based	base	VBN
cord-006460-3ayc0hne	472	29	differences	difference	NNS
cord-006460-3ayc0hne	472	30	in	in	IN
cord-006460-3ayc0hne	472	31	outcome	outcome	NN
cord-006460-3ayc0hne	472	32	with	with	IN
cord-006460-3ayc0hne	472	33	patients	patient	NNS
cord-006460-3ayc0hne	472	34	with	with	IN
cord-006460-3ayc0hne	472	35	sepsis	sepsis	NN
cord-006460-3ayc0hne	472	36	Genderdependent	Genderdependent	NNP
cord-006460-3ayc0hne	472	37	differences	difference	NNS
cord-006460-3ayc0hne	472	38	in	in	IN
cord-006460-3ayc0hne	472	39	outcome	outcome	NN
cord-006460-3ayc0hne	472	40	after	after	IN
cord-006460-3ayc0hne	472	41	the	the	DT
cord-006460-3ayc0hne	472	42	treatment	treatment	NN
cord-006460-3ayc0hne	472	43	of	of	IN
cord-006460-3ayc0hne	472	44	infection	infection	NN
cord-006460-3ayc0hne	472	45	in	in	IN
cord-006460-3ayc0hne	472	46	hospitalized	hospitalize	VBN
cord-006460-3ayc0hne	472	47	patients	patient	NNS
cord-006460-3ayc0hne	473	1	Male	male	JJ
cord-006460-3ayc0hne	473	2	gender	gender	NN
cord-006460-3ayc0hne	473	3	is	be	VBZ
cord-006460-3ayc0hne	473	4	a	a	DT
cord-006460-3ayc0hne	473	5	risk	risk	NN
cord-006460-3ayc0hne	473	6	factor	factor	NN
cord-006460-3ayc0hne	473	7	for	for	IN
cord-006460-3ayc0hne	473	8	major	major	JJ
cord-006460-3ayc0hne	473	9	infections	infection	NNS
cord-006460-3ayc0hne	473	10	after	after	IN
cord-006460-3ayc0hne	473	11	surgery	surgery	NN
cord-006460-3ayc0hne	473	12	Multiple	Multiple	NNP
cord-006460-3ayc0hne	473	13	Sclerosis	Sclerosis	NNP
cord-006460-3ayc0hne	473	14	and	and	CC
cord-006460-3ayc0hne	473	15	Autoimmunity	Autoimmunity	NNP
cord-006460-3ayc0hne	473	16	(	(	-LRB-
cord-006460-3ayc0hne	473	17	1999	1999	CD
cord-006460-3ayc0hne	473	18	)	)	-RRB-
cord-006460-3ayc0hne	474	1	A	a	DT
cord-006460-3ayc0hne	474	2	gender	gender	NN
cord-006460-3ayc0hne	474	3	gap	gap	NN
cord-006460-3ayc0hne	474	4	in	in	IN
cord-006460-3ayc0hne	474	5	autoimmunity	autoimmunity	IN
cord-006460-3ayc0hne	474	6	Post	post	JJ
cord-006460-3ayc0hne	474	7	-	-	JJ
cord-006460-3ayc0hne	474	8	hemorrhagic	hemorrhagic	JJ
cord-006460-3ayc0hne	474	9	shock	shock	NN
cord-006460-3ayc0hne	474	10	mesenteric	mesenteric	JJ
cord-006460-3ayc0hne	474	11	lymph	lymph	NN
cord-006460-3ayc0hne	474	12	is	be	VBZ
cord-006460-3ayc0hne	474	13	cytotoxic	cytotoxic	JJ
cord-006460-3ayc0hne	474	14	to	to	IN
cord-006460-3ayc0hne	474	15	endothelial	endothelial	JJ
cord-006460-3ayc0hne	474	16	cells	cell	NNS
cord-006460-3ayc0hne	474	17	and	and	CC
cord-006460-3ayc0hne	474	18	activates	activate	VBZ
cord-006460-3ayc0hne	474	19	neutrophils	neutrophil	NNS
cord-006460-3ayc0hne	474	20	Thoracic	thoracic	JJ
cord-006460-3ayc0hne	474	21	duct	duct	NN
cord-006460-3ayc0hne	474	22	in	in	IN
cord-006460-3ayc0hne	474	23	patients	patient	NNS
cord-006460-3ayc0hne	474	24	with	with	IN
cord-006460-3ayc0hne	474	25	multiple	multiple	JJ
cord-006460-3ayc0hne	474	26	organ	organ	NN
cord-006460-3ayc0hne	474	27	failure	failure	NN
cord-006460-3ayc0hne	474	28	:	:	:
cord-006460-3ayc0hne	474	29	no	no	DT
cord-006460-3ayc0hne	474	30	major	major	JJ
cord-006460-3ayc0hne	474	31	route	route	NN
cord-006460-3ayc0hne	474	32	of	of	IN
cord-006460-3ayc0hne	474	33	bacterial	bacterial	JJ
cord-006460-3ayc0hne	474	34	translocation	translocation	NN
cord-006460-3ayc0hne	474	35	Mesenteric	Mesenteric	NNP
cord-006460-3ayc0hne	474	36	lymph	lymph	NNS
cord-006460-3ayc0hne	474	37	:	:	:
cord-006460-3ayc0hne	474	38	the	the	DT
cord-006460-3ayc0hne	474	39	critical	critical	JJ
cord-006460-3ayc0hne	474	40	bridge	bridge	NN
cord-006460-3ayc0hne	474	41	between	between	IN
cord-006460-3ayc0hne	474	42	dysfunctional	dysfunctional	JJ
cord-006460-3ayc0hne	474	43	gut	gut	NN
cord-006460-3ayc0hne	474	44	and	and	CC
cord-006460-3ayc0hne	474	45	multiple	multiple	JJ
cord-006460-3ayc0hne	474	46	organ	organ	NN
cord-006460-3ayc0hne	474	47	failure	failure	NN
cord-006460-3ayc0hne	475	1	Translocating	translocate	VBG
cord-006460-3ayc0hne	475	2	gut	gut	NN
cord-006460-3ayc0hne	475	3	bacteria	bacteria	NNS
cord-006460-3ayc0hne	475	4	reach	reach	VBP
cord-006460-3ayc0hne	475	5	the	the	DT
cord-006460-3ayc0hne	475	6	pulmonary	pulmonary	JJ
cord-006460-3ayc0hne	475	7	artery	artery	NN
cord-006460-3ayc0hne	475	8	by	by	IN
cord-006460-3ayc0hne	475	9	means	mean	NNS
cord-006460-3ayc0hne	475	10	of	of	IN
cord-006460-3ayc0hne	475	11	the	the	DT
cord-006460-3ayc0hne	475	12	thoracic	thoracic	JJ
cord-006460-3ayc0hne	475	13	duct	duct	NN
cord-006460-3ayc0hne	475	14	during	during	IN
cord-006460-3ayc0hne	475	15	hemorrhagic	hemorrhagic	JJ
cord-006460-3ayc0hne	475	16	shock	shock	NN
cord-006460-3ayc0hne	475	17	Gut	gut	NN
cord-006460-3ayc0hne	475	18	-	-	HYPH
cord-006460-3ayc0hne	475	19	derived	derive	VBN
cord-006460-3ayc0hne	475	20	mesenteric	mesenteric	JJ
cord-006460-3ayc0hne	475	21	lymph	lymph	NN
cord-006460-3ayc0hne	475	22	:	:	:
cord-006460-3ayc0hne	476	1	a	a	DT
cord-006460-3ayc0hne	476	2	link	link	NN
cord-006460-3ayc0hne	476	3	between	between	IN
cord-006460-3ayc0hne	476	4	burn	burn	NN
cord-006460-3ayc0hne	476	5	and	and	CC
cord-006460-3ayc0hne	476	6	lung	lung	NN
cord-006460-3ayc0hne	476	7	injury	injury	NN
cord-006460-3ayc0hne	476	8	Inflammatorisches	Inflammatorisches	NNP
cord-006460-3ayc0hne	476	9	Syndrom	Syndrom	NNP
cord-006460-3ayc0hne	476	10	nach	nach	NNP
cord-006460-3ayc0hne	476	11	endovaskulären	endovaskulären	NNP
cord-006460-3ayc0hne	476	12	Aortenstentimplatationen	Aortenstentimplatationen	NNP
cord-006460-3ayc0hne	476	13	-eine	-eine	HYPH
cord-006460-3ayc0hne	476	14	vergleichende	vergleichende	NNP
cord-006460-3ayc0hne	476	15	studie	studie	NNP
cord-006460-3ayc0hne	476	16	Neutrophil	Neutrophil	NNP
cord-006460-3ayc0hne	476	17	-	-	HYPH
cord-006460-3ayc0hne	476	18	platelet	platelet	NN
cord-006460-3ayc0hne	476	19	interactions	interaction	NNS
cord-006460-3ayc0hne	476	20	in	in	IN
cord-006460-3ayc0hne	476	21	sepsis	sepsis	NN
cord-006460-3ayc0hne	477	1	The	the	DT
cord-006460-3ayc0hne	477	2	impact	impact	NN
cord-006460-3ayc0hne	477	3	of	of	IN
cord-006460-3ayc0hne	477	4	the	the	DT
cord-006460-3ayc0hne	477	5	polymerase	polymerase	NN
cord-006460-3ayc0hne	477	6	chain	chain	NN
cord-006460-3ayc0hne	477	7	reaction	reaction	NN
cord-006460-3ayc0hne	477	8	in	in	IN
cord-006460-3ayc0hne	477	9	clinical	clinical	JJ
cord-006460-3ayc0hne	477	10	medicine	medicine	NN
cord-006460-3ayc0hne	477	11	Polymerase	Polymerase	NNP
cord-006460-3ayc0hne	477	12	chain	chain	NN
cord-006460-3ayc0hne	477	13	reaction	reaction	NN
cord-006460-3ayc0hne	477	14	surveillance	surveillance	NN
cord-006460-3ayc0hne	477	15	of	of	IN
cord-006460-3ayc0hne	477	16	fungal	fungal	JJ
cord-006460-3ayc0hne	477	17	DNA	dna	NN
cord-006460-3ayc0hne	477	18	in	in	IN
cord-006460-3ayc0hne	477	19	critically	critically	RB
cord-006460-3ayc0hne	477	20	ill	ill	JJ
cord-006460-3ayc0hne	477	21	patients	patient	NNS
cord-006460-3ayc0hne	477	22	with	with	IN
cord-006460-3ayc0hne	477	23	systemic	systemic	JJ
cord-006460-3ayc0hne	477	24	inflammatory	inflammatory	JJ
cord-006460-3ayc0hne	477	25	response	response	NN
cord-006460-3ayc0hne	477	26	syndrome	syndrome	NN
cord-006460-3ayc0hne	477	27	Detection	detection	NN
cord-006460-3ayc0hne	477	28	of	of	IN
cord-006460-3ayc0hne	477	29	bacterial	bacterial	JJ
cord-006460-3ayc0hne	477	30	DNA	dna	NN
cord-006460-3ayc0hne	477	31	in	in	IN
cord-006460-3ayc0hne	477	32	the	the	DT
cord-006460-3ayc0hne	477	33	plasma	plasma	NN
cord-006460-3ayc0hne	477	34	of	of	IN
cord-006460-3ayc0hne	477	35	patients	patient	NNS
cord-006460-3ayc0hne	477	36	with	with	IN
cord-006460-3ayc0hne	477	37	sepsis	sepsis	NN
cord-006460-3ayc0hne	477	38	,	,	,
cord-006460-3ayc0hne	477	39	severe	severe	JJ
cord-006460-3ayc0hne	477	40	sepsis	sepsis	NN
cord-006460-3ayc0hne	477	41	and	and	CC
cord-006460-3ayc0hne	478	1	multiple	multiple	JJ
cord-006460-3ayc0hne	478	2	organ	organ	NN
cord-006460-3ayc0hne	478	3	dysfunction	dysfunction	NN
cord-006460-3ayc0hne	478	4	syndrome	syndrome	NN
cord-006460-3ayc0hne	478	5	Septic	septic	JJ
cord-006460-3ayc0hne	478	6	shock	shock	NN
cord-006460-3ayc0hne	478	7	without	without	IN
cord-006460-3ayc0hne	478	8	documented	document	VBN
cord-006460-3ayc0hne	478	9	infection	infection	NN
cord-006460-3ayc0hne	478	10	:	:	:
cord-006460-3ayc0hne	478	11	an	an	DT
cord-006460-3ayc0hne	478	12	uncommon	uncommon	JJ
cord-006460-3ayc0hne	478	13	entity	entity	NN
cord-006460-3ayc0hne	478	14	with	with	IN
cord-006460-3ayc0hne	478	15	a	a	DT
cord-006460-3ayc0hne	478	16	high	high	JJ
cord-006460-3ayc0hne	478	17	mortality	mortality	NN
cord-006460-3ayc0hne	478	18	Superantigen	Superantigen	NNP
cord-006460-3ayc0hne	478	19	-	-	HYPH
cord-006460-3ayc0hne	478	20	mediated	mediate	VBN
cord-006460-3ayc0hne	478	21	lethal	lethal	JJ
cord-006460-3ayc0hne	478	22	shock	shock	NN
cord-006460-3ayc0hne	478	23	:	:	:
cord-006460-3ayc0hne	478	24	the	the	DT
cord-006460-3ayc0hne	478	25	functional	functional	JJ
cord-006460-3ayc0hne	478	26	state	state	NN
cord-006460-3ayc0hne	478	27	of	of	IN
cord-006460-3ayc0hne	478	28	ligand	ligand	NN
cord-006460-3ayc0hne	478	29	-	-	HYPH
cord-006460-3ayc0hne	478	30	reactive	reactive	JJ
cord-006460-3ayc0hne	478	31	T	t	NN
cord-006460-3ayc0hne	478	32	cells	cell	NNS
cord-006460-3ayc0hne	479	1	Helicobacter	helicobacter	NN
cord-006460-3ayc0hne	479	2	pylori	pylori	NN
cord-006460-3ayc0hne	479	3	virulence	virulence	NN
cord-006460-3ayc0hne	479	4	and	and	CC
cord-006460-3ayc0hne	479	5	genetic	genetic	JJ
cord-006460-3ayc0hne	479	6	geography	geography	NN
cord-006460-3ayc0hne	480	1	Helicobacter	Helicobacter	NNP
cord-006460-3ayc0hne	480	2	pylori	pylori	NN
cord-006460-3ayc0hne	480	3	infection	infection	NN
cord-006460-3ayc0hne	480	4	in	in	IN
cord-006460-3ayc0hne	480	5	intensive	intensive	JJ
cord-006460-3ayc0hne	480	6	care	care	NN
cord-006460-3ayc0hne	480	7	:	:	:
cord-006460-3ayc0hne	480	8	increased	increase	VBN
cord-006460-3ayc0hne	480	9	prevalence	prevalence	NN
cord-006460-3ayc0hne	480	10	and	and	CC
cord-006460-3ayc0hne	480	11	a	a	DT
cord-006460-3ayc0hne	480	12	new	new	JJ
cord-006460-3ayc0hne	480	13	nosocomial	nosocomial	JJ
cord-006460-3ayc0hne	480	14	infection	infection	NN
cord-006460-3ayc0hne	481	1	Circulating	circulate	VBG
cord-006460-3ayc0hne	481	2	postinjury	postinjury	NNP
cord-006460-3ayc0hne	481	3	neutrophils	neutrophil	NNS
cord-006460-3ayc0hne	481	4	are	be	VBP
cord-006460-3ayc0hne	481	5	primed	prime	VBN
cord-006460-3ayc0hne	481	6	for	for	IN
cord-006460-3ayc0hne	481	7	the	the	DT
cord-006460-3ayc0hne	481	8	release	release	NN
cord-006460-3ayc0hne	481	9	of	of	IN
cord-006460-3ayc0hne	481	10	proinflammatory	proinflammatory	JJ
cord-006460-3ayc0hne	481	11	cytokines	cytokine	NNS
cord-006460-3ayc0hne	481	12	Early	early	RB
cord-006460-3ayc0hne	481	13	neutrophil	neutrophil	NN
cord-006460-3ayc0hne	481	14	sequestration	sequestration	NN
cord-006460-3ayc0hne	481	15	after	after	IN
cord-006460-3ayc0hne	481	16	injury	injury	NN
cord-006460-3ayc0hne	481	17	:	:	:
cord-006460-3ayc0hne	481	18	a	a	DT
cord-006460-3ayc0hne	481	19	pathogenic	pathogenic	JJ
cord-006460-3ayc0hne	481	20	mechanism	mechanism	NN
cord-006460-3ayc0hne	481	21	for	for	IN
cord-006460-3ayc0hne	481	22	multiple	multiple	JJ
cord-006460-3ayc0hne	481	23	organ	organ	NN
cord-006460-3ayc0hne	481	24	failure	failure	NN
cord-006460-3ayc0hne	481	25	Sequential	sequential	JJ
cord-006460-3ayc0hne	481	26	systemic	systemic	JJ
cord-006460-3ayc0hne	481	27	platelet	platelet	NN
cord-006460-3ayc0hne	481	28	-	-	HYPH
cord-006460-3ayc0hne	481	29	activating	activate	VBG
cord-006460-3ayc0hne	481	30	factor	factor	NN
cord-006460-3ayc0hne	481	31	and	and	CC
cord-006460-3ayc0hne	481	32	interleukin	interleukin	NN
cord-006460-3ayc0hne	482	1	8	8	CD
cord-006460-3ayc0hne	482	2	primes	primes	JJ
cord-006460-3ayc0hne	482	3	neutrophils	neutrophil	NNS
cord-006460-3ayc0hne	482	4	in	in	IN
cord-006460-3ayc0hne	482	5	patients	patient	NNS
cord-006460-3ayc0hne	482	6	with	with	IN
cord-006460-3ayc0hne	482	7	trauma	trauma	NN
cord-006460-3ayc0hne	482	8	at	at	IN
cord-006460-3ayc0hne	482	9	risk	risk	NN
cord-006460-3ayc0hne	482	10	of	of	IN
cord-006460-3ayc0hne	482	11	multiple	multiple	JJ
cord-006460-3ayc0hne	482	12	organ	organ	NN
cord-006460-3ayc0hne	482	13	failure	failure	NN
cord-006460-3ayc0hne	482	14	Does	do	VBZ
cord-006460-3ayc0hne	482	15	programmed	program	VBN
cord-006460-3ayc0hne	482	16	cell	cell	NN
cord-006460-3ayc0hne	482	17	death	death	NN
cord-006460-3ayc0hne	482	18	(	(	-LRB-
cord-006460-3ayc0hne	482	19	apoptosis	apoptosis	NN
cord-006460-3ayc0hne	482	20	)	)	-RRB-
cord-006460-3ayc0hne	482	21	play	play	VB
cord-006460-3ayc0hne	482	22	a	a	DT
cord-006460-3ayc0hne	482	23	role	role	NN
cord-006460-3ayc0hne	482	24	in	in	IN
cord-006460-3ayc0hne	482	25	the	the	DT
cord-006460-3ayc0hne	482	26	development	development	NN
cord-006460-3ayc0hne	482	27	of	of	IN
cord-006460-3ayc0hne	482	28	multiple	multiple	JJ
cord-006460-3ayc0hne	482	29	organ	organ	NN
cord-006460-3ayc0hne	482	30	dysfunction	dysfunction	NN
cord-006460-3ayc0hne	482	31	in	in	IN
cord-006460-3ayc0hne	482	32	critically	critically	RB
cord-006460-3ayc0hne	482	33	ill	ill	JJ
cord-006460-3ayc0hne	482	34	patients	patient	NNS
cord-006460-3ayc0hne	482	35	?	?	.
cord-006460-3ayc0hne	483	1	A	a	DT
cord-006460-3ayc0hne	483	2	review	review	NN
cord-006460-3ayc0hne	483	3	and	and	CC
cord-006460-3ayc0hne	483	4	a	a	DT
cord-006460-3ayc0hne	483	5	theoretical	theoretical	JJ
cord-006460-3ayc0hne	483	6	framework	framework	NN
cord-006460-3ayc0hne	483	7	GCSF	GCSF	NNP
cord-006460-3ayc0hne	483	8	treatment	treatment	NN
cord-006460-3ayc0hne	483	9	of	of	IN
cord-006460-3ayc0hne	483	10	normal	normal	JJ
cord-006460-3ayc0hne	483	11	volunteers	volunteer	NNS
cord-006460-3ayc0hne	483	12	induces	induce	VBZ
cord-006460-3ayc0hne	483	13	a	a	DT
cord-006460-3ayc0hne	483	14	sustained	sustained	JJ
cord-006460-3ayc0hne	483	15	immunomodulation	immunomodulation	NN
cord-006460-3ayc0hne	483	16	characterized	characterize	VBN
cord-006460-3ayc0hne	483	17	by	by	IN
cord-006460-3ayc0hne	483	18	an	an	DT
cord-006460-3ayc0hne	483	19	anti	anti	JJ
cord-006460-3ayc0hne	483	20	-	-	JJ
cord-006460-3ayc0hne	483	21	inflammatory	inflammatory	JJ
cord-006460-3ayc0hne	483	22	cytokine	cytokine	NN
cord-006460-3ayc0hne	483	23	response	response	NN
cord-006460-3ayc0hne	483	24	Granulocyte	Granulocyte	NNP
cord-006460-3ayc0hne	483	25	colonystimulating	colonystimulating	NN
cord-006460-3ayc0hne	483	26	factor	factor	NN
cord-006460-3ayc0hne	483	27	(	(	-LRB-
cord-006460-3ayc0hne	483	28	GCSF	GCSF	NNP
cord-006460-3ayc0hne	483	29	)	)	-RRB-
cord-006460-3ayc0hne	483	30	in	in	IN
cord-006460-3ayc0hne	483	31	the	the	DT
cord-006460-3ayc0hne	483	32	treatment	treatment	NN
cord-006460-3ayc0hne	483	33	of	of	IN
cord-006460-3ayc0hne	483	34	severe	severe	JJ
cord-006460-3ayc0hne	483	35	pneumonia	pneumonia	NN
cord-006460-3ayc0hne	483	36	,	,	,
cord-006460-3ayc0hne	483	37	sepsis	sepsis	NN
cord-006460-3ayc0hne	483	38	and	and	CC
cord-006460-3ayc0hne	483	39	septic	septic	JJ
cord-006460-3ayc0hne	483	40	shock	shock	NN
cord-006460-3ayc0hne	483	41	Increased	increase	VBN
cord-006460-3ayc0hne	483	42	survival	survival	NN
cord-006460-3ayc0hne	483	43	after	after	IN
cord-006460-3ayc0hne	483	44	major	major	JJ
cord-006460-3ayc0hne	483	45	thermal	thermal	JJ
cord-006460-3ayc0hne	483	46	injury	injury	NN
cord-006460-3ayc0hne	483	47	:	:	:
cord-006460-3ayc0hne	483	48	the	the	DT
cord-006460-3ayc0hne	483	49	effect	effect	NN
cord-006460-3ayc0hne	483	50	of	of	IN
cord-006460-3ayc0hne	483	51	growth	growth	NN
cord-006460-3ayc0hne	483	52	hormone	hormone	NN
cord-006460-3ayc0hne	483	53	therapy	therapy	NN
cord-006460-3ayc0hne	483	54	in	in	IN
cord-006460-3ayc0hne	483	55	adults	adult	NNS
cord-006460-3ayc0hne	484	1	A	a	DT
cord-006460-3ayc0hne	484	2	new	new	JJ
cord-006460-3ayc0hne	484	3	treatment	treatment	NN
cord-006460-3ayc0hne	484	4	for	for	IN
cord-006460-3ayc0hne	484	5	patients	patient	NNS
cord-006460-3ayc0hne	484	6	with	with	IN
cord-006460-3ayc0hne	484	7	shortbowel	shortbowel	NNP
cord-006460-3ayc0hne	484	8	syndrome	syndrome	NN
cord-006460-3ayc0hne	484	9	:	:	:
cord-006460-3ayc0hne	485	1	growth	growth	NN
cord-006460-3ayc0hne	485	2	hormone	hormone	NN
cord-006460-3ayc0hne	485	3	,	,	,
cord-006460-3ayc0hne	485	4	glutamine	glutamine	NN
cord-006460-3ayc0hne	485	5	,	,	,
cord-006460-3ayc0hne	485	6	and	and	CC
cord-006460-3ayc0hne	485	7	a	a	DT
cord-006460-3ayc0hne	485	8	modified	modify	VBN
cord-006460-3ayc0hne	485	9	diet	diet	NN
cord-006460-3ayc0hne	485	10	Characterization	characterization	NN
cord-006460-3ayc0hne	485	11	of	of	IN
cord-006460-3ayc0hne	485	12	growth	growth	NN
cord-006460-3ayc0hne	485	13	hormone	hormone	NN
cord-006460-3ayc0hne	485	14	enhanced	enhance	VBN
cord-006460-3ayc0hne	485	15	donor	donor	NN
cord-006460-3ayc0hne	485	16	site	site	NN
cord-006460-3ayc0hne	485	17	healing	healing	NN
cord-006460-3ayc0hne	485	18	in	in	IN
cord-006460-3ayc0hne	485	19	patients	patient	NNS
cord-006460-3ayc0hne	485	20	with	with	IN
cord-006460-3ayc0hne	485	21	large	large	JJ
cord-006460-3ayc0hne	485	22	cutaneous	cutaneous	JJ
cord-006460-3ayc0hne	485	23	burns	burn	NNS
cord-006460-3ayc0hne	485	24	Priming	Priming	NNP
cord-006460-3ayc0hne	485	25	of	of	IN
cord-006460-3ayc0hne	485	26	the	the	DT
cord-006460-3ayc0hne	485	27	neutrophil	neutrophil	NN
cord-006460-3ayc0hne	485	28	respiratory	respiratory	JJ
cord-006460-3ayc0hne	485	29	burst	burst	NN
cord-006460-3ayc0hne	485	30	is	be	VBZ
cord-006460-3ayc0hne	485	31	species	species	NN
cord-006460-3ayc0hne	485	32	-	-	HYPH
cord-006460-3ayc0hne	485	33	dependent	dependent	JJ
cord-006460-3ayc0hne	485	34	and	and	CC
cord-006460-3ayc0hne	485	35	involves	involve	VBZ
cord-006460-3ayc0hne	485	36	MAP	map	NN
cord-006460-3ayc0hne	485	37	kinase	kinase	NN
cord-006460-3ayc0hne	485	38	activation	activation	NN
cord-006460-3ayc0hne	485	39	Molecular	molecular	JJ
cord-006460-3ayc0hne	485	40	mimicry	mimicry	NN
cord-006460-3ayc0hne	485	41	and	and	CC
cord-006460-3ayc0hne	485	42	autoimmunity	autoimmunity	IN
cord-006460-3ayc0hne	485	43	Systemic	systemic	JJ
cord-006460-3ayc0hne	485	44	inflammatory	inflammatory	JJ
cord-006460-3ayc0hne	485	45	response	response	NN
cord-006460-3ayc0hne	485	46	syndrome	syndrome	NN
cord-006460-3ayc0hne	485	47	(	(	-LRB-
cord-006460-3ayc0hne	485	48	SIRS	SIRS	NNP
cord-006460-3ayc0hne	485	49	)	)	-RRB-
cord-006460-3ayc0hne	485	50	,	,	,
cord-006460-3ayc0hne	485	51	multiple	multiple	JJ
cord-006460-3ayc0hne	485	52	organ	organ	NN
cord-006460-3ayc0hne	485	53	dysfunction	dysfunction	NN
cord-006460-3ayc0hne	485	54	syndrome	syndrome	NN
cord-006460-3ayc0hne	485	55	(	(	-LRB-
cord-006460-3ayc0hne	485	56	MODS	MODS	NNP
cord-006460-3ayc0hne	485	57	)	)	-RRB-
cord-006460-3ayc0hne	485	58	,	,	,
cord-006460-3ayc0hne	485	59	multiple	multiple	JJ
cord-006460-3ayc0hne	485	60	organ	organ	NN
cord-006460-3ayc0hne	485	61	failure	failure	NN
cord-006460-3ayc0hne	485	62	(	(	-LRB-
cord-006460-3ayc0hne	485	63	MOF	MOF	NNP
cord-006460-3ayc0hne	485	64	)	)	-RRB-
cord-006460-3ayc0hne	485	65	:	:	:
cord-006460-3ayc0hne	485	66	are	be	VBP
cord-006460-3ayc0hne	485	67	we	-PRON-	PRP
cord-006460-3ayc0hne	485	68	winning	win	VBG
cord-006460-3ayc0hne	485	69	the	the	DT
cord-006460-3ayc0hne	485	70	battle	battle	NN
cord-006460-3ayc0hne	485	71	?	?	.
cord-006460-3ayc0hne	486	1	Multiple	multiple	JJ
cord-006460-3ayc0hne	486	2	organ	organ	NN
cord-006460-3ayc0hne	486	3	failure	failure	NN
cord-006460-3ayc0hne	486	4	,	,	,
cord-006460-3ayc0hne	486	5	multiple	multiple	JJ
cord-006460-3ayc0hne	486	6	organ	organ	NN
cord-006460-3ayc0hne	486	7	dysfunction	dysfunction	NN
cord-006460-3ayc0hne	486	8	syndrome	syndrome	NN
cord-006460-3ayc0hne	486	9	,	,	,
cord-006460-3ayc0hne	486	10	and	and	CC
cord-006460-3ayc0hne	486	11	the	the	DT
cord-006460-3ayc0hne	486	12	systemic	systemic	JJ
cord-006460-3ayc0hne	486	13	inflammatory	inflammatory	JJ
cord-006460-3ayc0hne	486	14	response	response	NN
cord-006460-3ayc0hne	486	15	syndrome	syndrome	NN
cord-006460-3ayc0hne	486	16	-where	-where	RB
cord-006460-3ayc0hne	487	1	do	do	VBP
cord-006460-3ayc0hne	487	2	we	-PRON-	PRP
cord-006460-3ayc0hne	487	3	stand	stand	VB
cord-006460-3ayc0hne	487	4	Multiple	multiple	JJ
cord-006460-3ayc0hne	487	5	organ	organ	NN
cord-006460-3ayc0hne	487	6	failure	failure	NN
cord-006460-3ayc0hne	487	7	:	:	:
cord-006460-3ayc0hne	487	8	is	be	VBZ
cord-006460-3ayc0hne	487	9	it	-PRON-	PRP
cord-006460-3ayc0hne	487	10	disappearing	disappear	VBG
cord-006460-3ayc0hne	487	11	?	?	.
cord-006460-3ayc0hne	488	1	A	a	DT
cord-006460-3ayc0hne	488	2	comparison	comparison	NN
cord-006460-3ayc0hne	488	3	of	of	IN
cord-006460-3ayc0hne	488	4	risks	risk	NNS
cord-006460-3ayc0hne	488	5	and	and	CC
cord-006460-3ayc0hne	488	6	outcomes	outcome	NNS
cord-006460-3ayc0hne	488	7	of	of	IN
cord-006460-3ayc0hne	488	8	patients	patient	NNS
cord-006460-3ayc0hne	488	9	with	with	IN
cord-006460-3ayc0hne	488	10	organ	organ	NN
cord-006460-3ayc0hne	488	11	system	system	NN
cord-006460-3ayc0hne	488	12	failure	failure	NN
cord-006460-3ayc0hne	488	13	:	:	:
cord-006460-3ayc0hne	488	14	1982	1982	CD
cord-006460-3ayc0hne	488	15	-	-	SYM
cord-006460-3ayc0hne	488	16	1990	1990	CD
cord-006460-3ayc0hne	488	17	Treatment	Treatment	NNP
cord-006460-3ayc0hne	488	18	results	result	NNS
cord-006460-3ayc0hne	488	19	of	of	IN
cord-006460-3ayc0hne	488	20	patients	patient	NNS
cord-006460-3ayc0hne	488	21	with	with	IN
cord-006460-3ayc0hne	488	22	multiple	multiple	JJ
cord-006460-3ayc0hne	488	23	trauma	trauma	NN
cord-006460-3ayc0hne	488	24	:	:	:
cord-006460-3ayc0hne	488	25	an	an	DT
cord-006460-3ayc0hne	488	26	analysis	analysis	NN
cord-006460-3ayc0hne	488	27	of	of	IN
cord-006460-3ayc0hne	488	28	3,406	3,406	CD
cord-006460-3ayc0hne	488	29	cases	case	NNS
cord-006460-3ayc0hne	488	30	treated	treat	VBN
cord-006460-3ayc0hne	488	31	between	between	IN
cord-006460-3ayc0hne	488	32	1972	1972	CD
cord-006460-3ayc0hne	488	33	and	and	CC
cord-006460-3ayc0hne	488	34	1991	1991	CD
cord-006460-3ayc0hne	488	35	in	in	IN
cord-006460-3ayc0hne	488	36	a	a	DT
cord-006460-3ayc0hne	488	37	German	german	JJ
cord-006460-3ayc0hne	488	38	level	level	NN
cord-006460-3ayc0hne	488	39	one	one	CD
cord-006460-3ayc0hne	488	40	trauma	trauma	NN
cord-006460-3ayc0hne	488	41	center	center	NN
cord-006460-3ayc0hne	489	1	The	the	DT
cord-006460-3ayc0hne	489	2	delayed	delay	VBN
cord-006460-3ayc0hne	489	3	hypersensitivity	hypersensitivity	NN
cord-006460-3ayc0hne	489	4	response	response	NN
cord-006460-3ayc0hne	489	5	and	and	CC
cord-006460-3ayc0hne	489	6	host	host	NN
cord-006460-3ayc0hne	489	7	resistance	resistance	NN
cord-006460-3ayc0hne	489	8	in	in	IN
cord-006460-3ayc0hne	489	9	surgical	surgical	JJ
cord-006460-3ayc0hne	489	10	patients	patient	NNS
cord-006460-3ayc0hne	490	1	-20	-20	CD
cord-006460-3ayc0hne	490	2	years	year	NNS
cord-006460-3ayc0hne	490	3	later	later	RB
cord-006460-3ayc0hne	490	4	The	the	DT
cord-006460-3ayc0hne	490	5	complications	complication	NNS
cord-006460-3ayc0hne	490	6	of	of	IN
cord-006460-3ayc0hne	490	7	trauma	trauma	NN
cord-006460-3ayc0hne	490	8	and	and	CC
cord-006460-3ayc0hne	490	9	their	-PRON-	PRP$
cord-006460-3ayc0hne	490	10	associated	associate	VBN
cord-006460-3ayc0hne	490	11	costs	cost	NNS
cord-006460-3ayc0hne	490	12	in	in	IN
cord-006460-3ayc0hne	490	13	a	a	DT
cord-006460-3ayc0hne	490	14	level	level	NN
cord-006460-3ayc0hne	490	15	I	-PRON-	PRP
cord-006460-3ayc0hne	490	16	trauma	trauma	NN
cord-006460-3ayc0hne	490	17	center	center	NN
cord-006460-3ayc0hne	490	18	Are	be	VBP
cord-006460-3ayc0hne	490	19	we	-PRON-	PRP
cord-006460-3ayc0hne	490	20	winning	win	VBG
cord-006460-3ayc0hne	490	21	the	the	DT
cord-006460-3ayc0hne	490	22	battle	battle	NN
cord-006460-3ayc0hne	490	23	in	in	IN
cord-006460-3ayc0hne	490	24	the	the	DT
cord-006460-3ayc0hne	490	25	surgical	surgical	JJ
cord-006460-3ayc0hne	490	26	intensive	intensive	JJ
cord-006460-3ayc0hne	490	27	care	care	NN
cord-006460-3ayc0hne	490	28	unit	unit	NN
cord-006460-3ayc0hne	490	29	?	?	.
cord-006460-3ayc0hne	491	1	The	the	DT
cord-006460-3ayc0hne	491	2	promissory	promissory	JJ
cord-006460-3ayc0hne	491	3	note	note	NN
cord-006460-3ayc0hne	491	4	in	in	IN
cord-006460-3ayc0hne	491	5	scientific	scientific	JJ
cord-006460-3ayc0hne	491	6	research	research	NN
cord-006460-3ayc0hne	491	7	Selenium	selenium	NN
cord-006460-3ayc0hne	491	8	systemic	systemic	JJ
cord-006460-3ayc0hne	491	9	immune	immune	JJ
cord-006460-3ayc0hne	491	10	response	response	NN
cord-006460-3ayc0hne	491	11	syndrome	syndrome	NN
cord-006460-3ayc0hne	491	12	,	,	,
cord-006460-3ayc0hne	491	13	sepsis	sepsis	NN
cord-006460-3ayc0hne	491	14	,	,	,
cord-006460-3ayc0hne	491	15	and	and	CC
cord-006460-3ayc0hne	491	16	outcome	outcome	VB
cord-006460-3ayc0hne	491	17	in	in	IN
cord-006460-3ayc0hne	491	18	critically	critically	RB
cord-006460-3ayc0hne	491	19	ill	ill	JJ
cord-006460-3ayc0hne	491	20	patients	patient	NNS
cord-006460-3ayc0hne	491	21	Nuclear	Nuclear	NNP
cord-006460-3ayc0hne	491	22	factorskappa	factorskappa	JJ
cord-006460-3ayc0hne	491	23	β	β	NN
cord-006460-3ayc0hne	491	24	and	and	CC
cord-006460-3ayc0hne	491	25	nitric	nitric	NN
cord-006460-3ayc0hne	491	26	oxide	oxide	NN
cord-006460-3ayc0hne	491	27	regulating	regulate	VBG
cord-006460-3ayc0hne	491	28	life	life	NN
cord-006460-3ayc0hne	491	29	and	and	CC
cord-006460-3ayc0hne	491	30	death	death	NN
cord-006460-3ayc0hne	491	31	:	:	:
cord-006460-3ayc0hne	491	32	nonsense	nonsense	NN
cord-006460-3ayc0hne	491	33	or	or	CC
cord-006460-3ayc0hne	491	34	harsh	harsh	JJ
cord-006460-3ayc0hne	491	35	reality	reality	NN
cord-006460-3ayc0hne	491	36	Early	early	JJ
cord-006460-3ayc0hne	491	37	osteosynthesis	osteosynthesis	NN
cord-006460-3ayc0hne	491	38	and	and	CC
cord-006460-3ayc0hne	491	39	prophylactic	prophylactic	JJ
cord-006460-3ayc0hne	491	40	ventilation	ventilation	NN
cord-006460-3ayc0hne	491	41	in	in	IN
cord-006460-3ayc0hne	491	42	the	the	DT
cord-006460-3ayc0hne	491	43	multi	multi	JJ
cord-006460-3ayc0hne	491	44	-	-	JJ
cord-006460-3ayc0hne	491	45	trauma	trauma	JJ
cord-006460-3ayc0hne	491	46	patient	patient	NN
cord-006460-3ayc0hne	492	1	An	an	DT
cord-006460-3ayc0hne	492	2	immune	immune	NN
cord-006460-3ayc0hne	492	3	-	-	HYPH
cord-006460-3ayc0hne	492	4	enhancing	enhance	VBG
cord-006460-3ayc0hne	492	5	enteral	enteral	JJ
cord-006460-3ayc0hne	492	6	diet	diet	NN
cord-006460-3ayc0hne	492	7	reduces	reduce	VBZ
cord-006460-3ayc0hne	492	8	mortality	mortality	NN
cord-006460-3ayc0hne	492	9	rate	rate	NN
cord-006460-3ayc0hne	492	10	and	and	CC
cord-006460-3ayc0hne	492	11	episodes	episode	NNS
cord-006460-3ayc0hne	492	12	of	of	IN
cord-006460-3ayc0hne	492	13	bacteremia	bacteremia	NN
cord-006460-3ayc0hne	492	14	in	in	IN
cord-006460-3ayc0hne	492	15	septic	septic	JJ
cord-006460-3ayc0hne	492	16	intensive	intensive	JJ
cord-006460-3ayc0hne	492	17	care	care	NN
cord-006460-3ayc0hne	492	18	unit	unit	NN
cord-006460-3ayc0hne	492	19	patients	patient	VBZ
cord-006460-3ayc0hne	492	20	Clinical	clinical	JJ
cord-006460-3ayc0hne	492	21	benefits	benefit	NNS
cord-006460-3ayc0hne	492	22	of	of	IN
cord-006460-3ayc0hne	492	23	cytokine	cytokine	NN
cord-006460-3ayc0hne	492	24	removal	removal	NN
cord-006460-3ayc0hne	492	25	with	with	IN
cord-006460-3ayc0hne	492	26	continuous	continuous	JJ
cord-006460-3ayc0hne	492	27	hemodiafiltration	hemodiafiltration	NN
cord-006460-3ayc0hne	492	28	(	(	-LRB-
cord-006460-3ayc0hne	492	29	CHDF	CHDF	NNP
cord-006460-3ayc0hne	492	30	)	)	-RRB-
cord-006460-3ayc0hne	492	31	in	in	IN
cord-006460-3ayc0hne	492	32	critical	critical	JJ
cord-006460-3ayc0hne	492	33	care	care	NN
cord-006460-3ayc0hne	492	34	Plasmafiltration	Plasmafiltration	NNP
cord-006460-3ayc0hne	492	35	in	in	IN
cord-006460-3ayc0hne	492	36	Sepsis	Sepsis	NNP
cord-006460-3ayc0hne	492	37	Study	Study	NNP
cord-006460-3ayc0hne	492	38	Group	Group	NNP
cord-006460-3ayc0hne	492	39	(	(	-LRB-
cord-006460-3ayc0hne	492	40	1999	1999	CD
cord-006460-3ayc0hne	492	41	)	)	-RRB-
cord-006460-3ayc0hne	493	1	Continuous	continuous	JJ
cord-006460-3ayc0hne	493	2	plasmafiltration	plasmafiltration	NN
cord-006460-3ayc0hne	493	3	in	in	IN
cord-006460-3ayc0hne	493	4	sepsis	sepsis	NN
cord-006460-3ayc0hne	493	5	syndrome	syndrome	NN
cord-006460-3ayc0hne	494	1	Persistent	persistent	JJ
cord-006460-3ayc0hne	494	2	occult	occult	JJ
cord-006460-3ayc0hne	494	3	hypoperfusion	hypoperfusion	NN
cord-006460-3ayc0hne	494	4	is	be	VBZ
cord-006460-3ayc0hne	494	5	associated	associate	VBN
cord-006460-3ayc0hne	494	6	with	with	IN
cord-006460-3ayc0hne	494	7	a	a	DT
cord-006460-3ayc0hne	494	8	significant	significant	JJ
cord-006460-3ayc0hne	494	9	increase	increase	NN
cord-006460-3ayc0hne	494	10	in	in	IN
cord-006460-3ayc0hne	494	11	infection	infection	NN
cord-006460-3ayc0hne	494	12	rate	rate	NN
cord-006460-3ayc0hne	494	13	and	and	CC
cord-006460-3ayc0hne	494	14	mortality	mortality	NN
cord-006460-3ayc0hne	494	15	in	in	IN
cord-006460-3ayc0hne	494	16	major	major	JJ
cord-006460-3ayc0hne	494	17	trauma	trauma	NN
cord-006460-3ayc0hne	494	18	patients	patient	NNS
cord-006460-3ayc0hne	495	1	Molecular	molecular	JJ
cord-006460-3ayc0hne	495	2	biology	biology	NN
cord-006460-3ayc0hne	495	3	and	and	CC
cord-006460-3ayc0hne	495	4	minimal	minimal	JJ
cord-006460-3ayc0hne	495	5	surgery	surgery	NN
cord-006460-3ayc0hne	496	1	Hemodynamic	Hemodynamic	NNP
cord-006460-3ayc0hne	496	2	patterns	pattern	NNS
cord-006460-3ayc0hne	496	3	of	of	IN
cord-006460-3ayc0hne	496	4	survivors	survivor	NNS
cord-006460-3ayc0hne	496	5	and	and	CC
cord-006460-3ayc0hne	496	6	nonsurvivors	nonsurvivor	NNS
cord-006460-3ayc0hne	496	7	during	during	IN
cord-006460-3ayc0hne	496	8	high	high	JJ
cord-006460-3ayc0hne	496	9	risk	risk	NN
cord-006460-3ayc0hne	496	10	elective	elective	JJ
cord-006460-3ayc0hne	496	11	surgical	surgical	JJ
cord-006460-3ayc0hne	496	12	operations	operation	NNS
cord-006460-3ayc0hne	496	13	Intraoperative	intraoperative	JJ
cord-006460-3ayc0hne	496	14	evaluation	evaluation	NN
cord-006460-3ayc0hne	496	15	of	of	IN
cord-006460-3ayc0hne	496	16	tissue	tissue	NN
cord-006460-3ayc0hne	496	17	perfusion	perfusion	NN
cord-006460-3ayc0hne	496	18	in	in	IN
cord-006460-3ayc0hne	496	19	high	high	JJ
cord-006460-3ayc0hne	496	20	-	-	HYPH
cord-006460-3ayc0hne	496	21	risk	risk	NN
cord-006460-3ayc0hne	496	22	patients	patient	NNS
cord-006460-3ayc0hne	496	23	by	by	IN
cord-006460-3ayc0hne	496	24	invasive	invasive	JJ
cord-006460-3ayc0hne	496	25	and	and	CC
cord-006460-3ayc0hne	496	26	noninvasive	noninvasive	JJ
cord-006460-3ayc0hne	496	27	hemodynamic	hemodynamic	JJ
cord-006460-3ayc0hne	496	28	monitoring	monitoring	NN
cord-006460-3ayc0hne	496	29	The	the	DT
cord-006460-3ayc0hne	496	30	use	use	NN
cord-006460-3ayc0hne	496	31	of	of	IN
cord-006460-3ayc0hne	496	32	oxygen	oxygen	NN
cord-006460-3ayc0hne	496	33	consumption	consumption	NN
cord-006460-3ayc0hne	496	34	and	and	CC
cord-006460-3ayc0hne	496	35	delivery	delivery	NN
cord-006460-3ayc0hne	496	36	as	as	IN
cord-006460-3ayc0hne	496	37	end	end	NN
cord-006460-3ayc0hne	496	38	points	point	NNS
cord-006460-3ayc0hne	496	39	for	for	IN
cord-006460-3ayc0hne	496	40	resuscitation	resuscitation	NN
cord-006460-3ayc0hne	496	41	in	in	IN
cord-006460-3ayc0hne	496	42	critically	critically	RB
cord-006460-3ayc0hne	496	43	ill	ill	JJ
cord-006460-3ayc0hne	496	44	patients	patient	NNS
cord-006460-3ayc0hne	496	45	Chaos	Chaos	NNP
cord-006460-3ayc0hne	496	46	and	and	CC
cord-006460-3ayc0hne	496	47	the	the	DT
cord-006460-3ayc0hne	496	48	limits	limit	NNS
cord-006460-3ayc0hne	496	49	of	of	IN
cord-006460-3ayc0hne	496	50	modern	modern	JJ
cord-006460-3ayc0hne	496	51	medicine	medicine	NN
cord-006460-3ayc0hne	496	52	An	an	DT
cord-006460-3ayc0hne	496	53	Introduction	introduction	NN
cord-006460-3ayc0hne	496	54	to	to	IN
cord-006460-3ayc0hne	496	55	the	the	DT
cord-006460-3ayc0hne	496	56	Study	Study	NNP
cord-006460-3ayc0hne	496	57	of	of	IN
cord-006460-3ayc0hne	496	58	Experimental	Experimental	NNP
cord-006460-3ayc0hne	496	59	Medicine	Medicine	NNP
cord-006460-3ayc0hne	496	60	(	(	-LRB-
cord-006460-3ayc0hne	496	61	translated	translate	VBN
cord-006460-3ayc0hne	496	62	by	by	IN
cord-006460-3ayc0hne	496	63	HC	HC	NNP
cord-006460-3ayc0hne	496	64	Green	Green	NNP
cord-006460-3ayc0hne	496	65	)	)	-RRB-
cord-006460-3ayc0hne	497	1	The	the	DT
cord-006460-3ayc0hne	497	2	Wisdom	Wisdom	NNP
cord-006460-3ayc0hne	497	3	of	of	IN
cord-006460-3ayc0hne	497	4	the	the	DT
cord-006460-3ayc0hne	497	5	Body	Body	NNP
cord-006460-3ayc0hne	497	6	.	.	.
cord-006460-3ayc0hne	498	1	Norton	Norton	NNP
cord-006460-3ayc0hne	498	2	,	,	,
cord-006460-3ayc0hne	498	3	New	New	NNP
cord-006460-3ayc0hne	498	4	York	York	NNP
cord-006460-3ayc0hne	498	5	119	119	CD
cord-006460-3ayc0hne	498	6	.	.	.
cord-006460-3ayc0hne	499	1	Schultz	Schultz	NNP
cord-006460-3ayc0hne	499	2	SG	SG	NNP
cord-006460-3ayc0hne	499	3	(	(	-LRB-
cord-006460-3ayc0hne	499	4	1996	1996	CD
cord-006460-3ayc0hne	499	5	)	)	-RRB-
cord-006460-3ayc0hne	500	1	Homeostasis	homeostasis	NN
cord-006460-3ayc0hne	500	2	,	,	,
cord-006460-3ayc0hne	500	3	humpty	humpty	NNP
cord-006460-3ayc0hne	500	4	dumpty	dumpty	NNP
cord-006460-3ayc0hne	500	5	and	and	CC
cord-006460-3ayc0hne	500	6	integrative	integrative	JJ
cord-006460-3ayc0hne	500	7	biology	biology	NN
cord-006460-3ayc0hne	500	8	news	news	NN
cord-006460-3ayc0hne	500	9	Physiologic	physiologic	JJ
cord-006460-3ayc0hne	500	10	stability	stability	NN
cord-006460-3ayc0hne	500	11	and	and	CC
cord-006460-3ayc0hne	500	12	physiologic	physiologic	JJ
cord-006460-3ayc0hne	500	13	state	state	NN
cord-006460-3ayc0hne	500	14	Reductionism	Reductionism	NNP
cord-006460-3ayc0hne	500	15	and	and	CC
cord-006460-3ayc0hne	500	16	biologic	biologic	JJ
cord-006460-3ayc0hne	500	17	systems	system	NNS
cord-006460-3ayc0hne	501	1	Experimental	experimental	JJ
cord-006460-3ayc0hne	501	2	human	human	JJ
cord-006460-3ayc0hne	501	3	endotoxemia	endotoxemia	NN
cord-006460-3ayc0hne	501	4	increases	increase	VBZ
cord-006460-3ayc0hne	501	5	cardiac	cardiac	JJ
cord-006460-3ayc0hne	501	6	regularity	regularity	NN
cord-006460-3ayc0hne	501	7	:	:	:
cord-006460-3ayc0hne	501	8	results	result	NNS
cord-006460-3ayc0hne	501	9	from	from	IN
cord-006460-3ayc0hne	501	10	a	a	DT
cord-006460-3ayc0hne	501	11	prospective	prospective	JJ
cord-006460-3ayc0hne	501	12	,	,	,
cord-006460-3ayc0hne	501	13	randomized	randomized	JJ
cord-006460-3ayc0hne	501	14	crossover	crossover	NN
cord-006460-3ayc0hne	501	15	trial	trial	NN
cord-006460-3ayc0hne	501	16	Uncoupling	uncoupling	NN
cord-006460-3ayc0hne	501	17	of	of	IN
cord-006460-3ayc0hne	501	18	biological	biological	JJ
cord-006460-3ayc0hne	501	19	oscillators	oscillator	NNS
cord-006460-3ayc0hne	501	20	:	:	:
cord-006460-3ayc0hne	501	21	a	a	DT
cord-006460-3ayc0hne	501	22	complementary	complementary	JJ
cord-006460-3ayc0hne	501	23	hypothesis	hypothesis	NN
cord-006460-3ayc0hne	501	24	concerning	concern	VBG
cord-006460-3ayc0hne	501	25	the	the	DT
cord-006460-3ayc0hne	501	26	pathogenesis	pathogenesis	NN
cord-006460-3ayc0hne	501	27	of	of	IN
cord-006460-3ayc0hne	501	28	multiple	multiple	JJ
cord-006460-3ayc0hne	501	29	organ	organ	NN
cord-006460-3ayc0hne	501	30	dysfunction	dysfunction	NN
cord-006460-3ayc0hne	501	31	syndrome	syndrome	NN
cord-006460-3ayc0hne	501	32	Physiologic	physiologic	JJ
cord-006460-3ayc0hne	501	33	classification	classification	NN
cord-006460-3ayc0hne	501	34	and	and	CC
cord-006460-3ayc0hne	501	35	stratification	stratification	NN
cord-006460-3ayc0hne	501	36	of	of	IN
cord-006460-3ayc0hne	501	37	illness	illness	NN
cord-006460-3ayc0hne	501	38	severity	severity	NN
cord-006460-3ayc0hne	501	39	of	of	IN
cord-006460-3ayc0hne	501	40	post	post	JJ
cord-006460-3ayc0hne	501	41	-	-	JJ
cord-006460-3ayc0hne	501	42	trauma	trauma	JJ
cord-006460-3ayc0hne	501	43	"	"	``
cord-006460-3ayc0hne	501	44	sepsis	sepsis	NN
cord-006460-3ayc0hne	501	45	"	"	''
cord-006460-3ayc0hne	501	46	patients	patient	NNS
cord-006460-3ayc0hne	501	47	as	as	IN
cord-006460-3ayc0hne	501	48	a	a	DT
cord-006460-3ayc0hne	501	49	basis	basis	NN
cord-006460-3ayc0hne	501	50	for	for	IN
cord-006460-3ayc0hne	501	51	randomization	randomization	NN
cord-006460-3ayc0hne	501	52	of	of	IN
cord-006460-3ayc0hne	501	53	clinical	clinical	JJ
cord-006460-3ayc0hne	501	54	trials	trial	NNS
cord-006460-3ayc0hne	501	55	Surgeon	Surgeon	NNP
cord-006460-3ayc0hne	501	56	to	to	IN
cord-006460-3ayc0hne	501	57	Soldiers	soldier	NNS
cord-006460-3ayc0hne	501	58	Academically	academically	RB
cord-006460-3ayc0hne	501	59	correct	correct	JJ
cord-006460-3ayc0hne	501	60	biology	biology	NN
cord-006460-3ayc0hne	501	61	From	from	IN
cord-006460-3ayc0hne	501	62	the	the	DT
cord-006460-3ayc0hne	501	63	world	world	NN
cord-006460-3ayc0hne	501	64	of	of	IN
cord-006460-3ayc0hne	501	65	science	science	NN
cord-006460-3ayc0hne	501	66	to	to	IN
cord-006460-3ayc0hne	501	67	the	the	DT
cord-006460-3ayc0hne	501	68	world	world	NN
cord-006460-3ayc0hne	501	69	of	of	IN
cord-006460-3ayc0hne	501	70	research	research	NN
cord-006460-3ayc0hne	501	71	Medicine	Medicine	NNP
cord-006460-3ayc0hne	501	72	and	and	CC
cord-006460-3ayc0hne	501	73	the	the	DT
cord-006460-3ayc0hne	501	74	new	new	JJ
cord-006460-3ayc0hne	501	75	millennium	millennium	NN
cord-006460-3ayc0hne	501	76	Ecclesiastes	Ecclesiastes	NNP
cord-006460-3ayc0hne	501	77	3:1	3:1	CD
cord-006460-3ayc0hne	501	78	.	.	.
cord-006460-3ayc0hne	502	1	The	the	DT
cord-006460-3ayc0hne	502	2	Holy	Holy	NNP
cord-006460-3ayc0hne	502	3	Bible	Bible	NNP
cord-006460-3ayc0hne	502	4	of	of	IN
cord-006460-3ayc0hne	502	5	King	King	NNP
cord-006460-3ayc0hne	502	6	James	James	NNP
cord-006460-3ayc0hne	502	7	Version	Version	NNP
cord-006460-3ayc0hne	502	8	1	1	CD
cord-006460-3ayc0hne	503	1	An	an	DT
cord-006460-3ayc0hne	503	2	address	address	NN
cord-006460-3ayc0hne	503	3	at	at	IN
cord-006460-3ayc0hne	503	4	an	an	DT
cord-006460-3ayc0hne	503	5	honorary	honorary	JJ
cord-006460-3ayc0hne	503	6	degree	degree	NN
cord-006460-3ayc0hne	503	7	presentation	presentation	NN
cord-006460-3ayc0hne	503	8	to	to	IN
cord-006460-3ayc0hne	503	9	Dr.	Dr.	NNP
cord-006460-3ayc0hne	503	10	Baue	Baue	NNP
cord-006460-3ayc0hne	503	11	by	by	IN
cord-006460-3ayc0hne	503	12	Ludwig	Ludwig	NNP
cord-006460-3ayc0hne	503	13	Maximillians	Maximillians	NNP
cord-006460-3ayc0hne	503	14	Universität	Universität	NNP
cord-006460-3ayc0hne	503	15	,	,	,
cord-006460-3ayc0hne	503	16	Munich	Munich	NNP
cord-006460-3ayc0hne	503	17	,	,	,
cord-006460-3ayc0hne	503	18	Germany	Germany	NNP
cord-006460-3ayc0hne	503	19	,	,	,
cord-006460-3ayc0hne	503	20	28	28	CD
cord-006460-3ayc0hne	503	21	February	February	NNP
cord-006460-3ayc0hne	503	22	2000	2000	CD
cord-006460-3ayc0hne	503	23	.	.	.