id	sid	tid	token	lemma	pos
cord-005603-kjcbbgse	1	1	key	key	JJ
cord-005603-kjcbbgse	1	2	:	:	:
cord-005603-kjcbbgse	1	3	cord-005603-kjcbbgse	cord-005603-kjcbbgse	NNP
cord-005603-kjcbbgse	2	1	authors	author	NNS
cord-005603-kjcbbgse	2	2	:	:	:
cord-005603-kjcbbgse	2	3	Brun	Brun	NNP
cord-005603-kjcbbgse	2	4	-	-	HYPH
cord-005603-kjcbbgse	2	5	Buisson	Buisson	NNP
cord-005603-kjcbbgse	2	6	,	,	,
cord-005603-kjcbbgse	3	1	C.	C.	NNP
cord-005603-kjcbbgse	3	2	title	title	NN
cord-005603-kjcbbgse	3	3	:	:	:
cord-005603-kjcbbgse	4	1	The	the	DT
cord-005603-kjcbbgse	4	2	epidemiology	epidemiology	NN
cord-005603-kjcbbgse	4	3	of	of	IN
cord-005603-kjcbbgse	4	4	the	the	DT
cord-005603-kjcbbgse	4	5	systemic	systemic	JJ
cord-005603-kjcbbgse	4	6	inflammatory	inflammatory	JJ
cord-005603-kjcbbgse	4	7	response	response	NN
cord-005603-kjcbbgse	4	8	date	date	NN
cord-005603-kjcbbgse	4	9	:	:	:
cord-005603-kjcbbgse	4	10	2000	2000	CD
cord-005603-kjcbbgse	4	11	journal	journal	NN
cord-005603-kjcbbgse	4	12	:	:	:
cord-005603-kjcbbgse	4	13	Intensive	Intensive	NNP
cord-005603-kjcbbgse	4	14	Care	care	NN
cord-005603-kjcbbgse	4	15	Med	Med	NNP
cord-005603-kjcbbgse	4	16	DOI	doi	NN
cord-005603-kjcbbgse	4	17	:	:	:
cord-005603-kjcbbgse	4	18	10.1007	10.1007	CD
cord-005603-kjcbbgse	4	19	/	/	SYM
cord-005603-kjcbbgse	4	20	s001340051121	s001340051121	NNP
cord-005603-kjcbbgse	4	21	sha	sha	NNP
cord-005603-kjcbbgse	4	22	:	:	:
cord-005603-kjcbbgse	4	23	1862da9d213b50e12f2e6eaea5692b84b16dc1ef	1862da9d213b50e12f2e6eaea5692b84b16dc1ef	CD
cord-005603-kjcbbgse	4	24	doc_id	doc_id	CD
cord-005603-kjcbbgse	4	25	:	:	:
cord-005603-kjcbbgse	4	26	5603	5603	CD
cord-005603-kjcbbgse	4	27	cord_uid	cord_uid	NNS
cord-005603-kjcbbgse	4	28	:	:	:
cord-005603-kjcbbgse	4	29	kjcbbgse	kjcbbgse	NNP
cord-005603-kjcbbgse	4	30	Objective	Objective	NNP
cord-005603-kjcbbgse	4	31	:	:	:
cord-005603-kjcbbgse	4	32	To	to	TO
cord-005603-kjcbbgse	4	33	examine	examine	VB
cord-005603-kjcbbgse	4	34	the	the	DT
cord-005603-kjcbbgse	4	35	incidence	incidence	NN
cord-005603-kjcbbgse	4	36	,	,	,
cord-005603-kjcbbgse	4	37	risk	risk	NN
cord-005603-kjcbbgse	4	38	factors	factor	NNS
cord-005603-kjcbbgse	4	39	,	,	,
cord-005603-kjcbbgse	4	40	aetiologies	aetiology	NNS
cord-005603-kjcbbgse	4	41	and	and	CC
cord-005603-kjcbbgse	4	42	outcome	outcome	NN
cord-005603-kjcbbgse	4	43	of	of	IN
cord-005603-kjcbbgse	4	44	the	the	DT
cord-005603-kjcbbgse	4	45	various	various	JJ
cord-005603-kjcbbgse	4	46	forms	form	NNS
cord-005603-kjcbbgse	4	47	of	of	IN
cord-005603-kjcbbgse	4	48	the	the	DT
cord-005603-kjcbbgse	4	49	septic	septic	JJ
cord-005603-kjcbbgse	4	50	syndromes	syndrome	NNS
cord-005603-kjcbbgse	4	51	(	(	-LRB-
cord-005603-kjcbbgse	4	52	the	the	DT
cord-005603-kjcbbgse	4	53	systemic	systemic	JJ
cord-005603-kjcbbgse	4	54	inflammatory	inflammatory	JJ
cord-005603-kjcbbgse	4	55	response	response	NN
cord-005603-kjcbbgse	4	56	syndrome	syndrome	NN
cord-005603-kjcbbgse	4	57	[	[	-LRB-
cord-005603-kjcbbgse	4	58	SIRS	sirs	UH
cord-005603-kjcbbgse	4	59	]	]	-RRB-
cord-005603-kjcbbgse	4	60	sepsis	sepsis	NN
cord-005603-kjcbbgse	4	61	,	,	,
cord-005603-kjcbbgse	4	62	severe	severe	JJ
cord-005603-kjcbbgse	4	63	sepsis	sepsis	NN
cord-005603-kjcbbgse	4	64	,	,	,
cord-005603-kjcbbgse	4	65	and	and	CC
cord-005603-kjcbbgse	4	66	septic	septic	JJ
cord-005603-kjcbbgse	4	67	shock	shock	NN
cord-005603-kjcbbgse	4	68	)	)	-RRB-
cord-005603-kjcbbgse	4	69	and	and	CC
cord-005603-kjcbbgse	4	70	their	-PRON-	PRP$
cord-005603-kjcbbgse	4	71	relationships	relationship	NNS
cord-005603-kjcbbgse	4	72	with	with	IN
cord-005603-kjcbbgse	4	73	infection.¶Design	infection.¶design	NN
cord-005603-kjcbbgse	4	74	:	:	:
cord-005603-kjcbbgse	4	75	Review	Review	NNP
cord-005603-kjcbbgse	4	76	of	of	IN
cord-005603-kjcbbgse	4	77	published	publish	VBN
cord-005603-kjcbbgse	4	78	cohort	cohort	NN
cord-005603-kjcbbgse	4	79	studies	study	NNS
cord-005603-kjcbbgse	4	80	examining	examine	VBG
cord-005603-kjcbbgse	4	81	the	the	DT
cord-005603-kjcbbgse	4	82	epidemiology	epidemiology	NN
cord-005603-kjcbbgse	4	83	of	of	IN
cord-005603-kjcbbgse	4	84	the	the	DT
cord-005603-kjcbbgse	4	85	septic	septic	JJ
cord-005603-kjcbbgse	4	86	syndromes	syndrome	NNS
cord-005603-kjcbbgse	4	87	,	,	,
cord-005603-kjcbbgse	4	88	with	with	IN
cord-005603-kjcbbgse	4	89	emphasis	emphasis	NN
cord-005603-kjcbbgse	4	90	on	on	IN
cord-005603-kjcbbgse	4	91	intensive	intensive	JJ
cord-005603-kjcbbgse	4	92	care	care	NN
cord-005603-kjcbbgse	4	93	unit	unit	NN
cord-005603-kjcbbgse	5	1	(	(	-LRB-
cord-005603-kjcbbgse	5	2	ICU	ICU	NNP
cord-005603-kjcbbgse	5	3	)	)	-RRB-
cord-005603-kjcbbgse	5	4	patients.¶Results	patients.¶Results	NNP
cord-005603-kjcbbgse	5	5	:	:	:
cord-005603-kjcbbgse	6	1	The	the	DT
cord-005603-kjcbbgse	6	2	prevalence	prevalence	NN
cord-005603-kjcbbgse	6	3	of	of	IN
cord-005603-kjcbbgse	6	4	SIRS	SIRS	NNP
cord-005603-kjcbbgse	6	5	is	be	VBZ
cord-005603-kjcbbgse	6	6	very	very	RB
cord-005603-kjcbbgse	6	7	high	high	JJ
cord-005603-kjcbbgse	6	8	,	,	,
cord-005603-kjcbbgse	6	9	affecting	affect	VBG
cord-005603-kjcbbgse	6	10	one	one	CD
cord-005603-kjcbbgse	6	11	-	-	HYPH
cord-005603-kjcbbgse	6	12	third	third	NN
cord-005603-kjcbbgse	6	13	of	of	IN
cord-005603-kjcbbgse	6	14	all	all	DT
cord-005603-kjcbbgse	6	15	in	in	IN
cord-005603-kjcbbgse	6	16	-	-	HYPH
cord-005603-kjcbbgse	6	17	hospital	hospital	NN
cord-005603-kjcbbgse	6	18	patients	patient	NNS
cord-005603-kjcbbgse	6	19	,	,	,
cord-005603-kjcbbgse	6	20	and	and	CC
cord-005603-kjcbbgse	6	21	>	>	XX
cord-005603-kjcbbgse	6	22	50	50	CD
cord-005603-kjcbbgse	6	23	%	%	NN
cord-005603-kjcbbgse	6	24	of	of	IN
cord-005603-kjcbbgse	6	25	all	all	DT
cord-005603-kjcbbgse	6	26	ICU	ICU	NNP
cord-005603-kjcbbgse	6	27	patients	patient	NNS
cord-005603-kjcbbgse	6	28	;	;	:
cord-005603-kjcbbgse	6	29	in	in	IN
cord-005603-kjcbbgse	6	30	surgical	surgical	JJ
cord-005603-kjcbbgse	6	31	ICU	ICU	NNP
cord-005603-kjcbbgse	6	32	patients	patient	NNS
cord-005603-kjcbbgse	6	33	,	,	,
cord-005603-kjcbbgse	6	34	SIRS	SIRS	NNP
cord-005603-kjcbbgse	6	35	occurs	occur	VBZ
cord-005603-kjcbbgse	6	36	in	in	IN
cord-005603-kjcbbgse	6	37	>	>	$
cord-005603-kjcbbgse	6	38	80	80	CD
cord-005603-kjcbbgse	6	39	%	%	NN
cord-005603-kjcbbgse	6	40	patients	patient	NNS
cord-005603-kjcbbgse	6	41	.	.	.
cord-005603-kjcbbgse	7	1	Trauma	trauma	NN
cord-005603-kjcbbgse	7	2	patients	patient	NNS
cord-005603-kjcbbgse	7	3	are	be	VBP
cord-005603-kjcbbgse	7	4	at	at	IN
cord-005603-kjcbbgse	7	5	particularly	particularly	RB
cord-005603-kjcbbgse	7	6	high	high	JJ
cord-005603-kjcbbgse	7	7	risk	risk	NN
cord-005603-kjcbbgse	7	8	of	of	IN
cord-005603-kjcbbgse	7	9	SIRS	SIRS	NNP
cord-005603-kjcbbgse	7	10	,	,	,
cord-005603-kjcbbgse	7	11	and	and	CC
cord-005603-kjcbbgse	7	12	most	most	JJS
cord-005603-kjcbbgse	7	13	these	these	DT
cord-005603-kjcbbgse	7	14	patients	patient	NNS
cord-005603-kjcbbgse	7	15	do	do	VBP
cord-005603-kjcbbgse	7	16	not	not	RB
cord-005603-kjcbbgse	7	17	have	have	VB
cord-005603-kjcbbgse	7	18	infection	infection	NN
cord-005603-kjcbbgse	7	19	documented	document	VBN
cord-005603-kjcbbgse	7	20	.	.	.
cord-005603-kjcbbgse	8	1	The	the	DT
cord-005603-kjcbbgse	8	2	prevalence	prevalence	NN
cord-005603-kjcbbgse	8	3	of	of	IN
cord-005603-kjcbbgse	8	4	infection	infection	NN
cord-005603-kjcbbgse	8	5	and	and	CC
cord-005603-kjcbbgse	8	6	bacteraemia	bacteraemia	NN
cord-005603-kjcbbgse	8	7	increases	increase	VBZ
cord-005603-kjcbbgse	8	8	with	with	IN
cord-005603-kjcbbgse	8	9	the	the	DT
cord-005603-kjcbbgse	8	10	number	number	NN
cord-005603-kjcbbgse	8	11	of	of	IN
cord-005603-kjcbbgse	8	12	SIRS	SIRS	NNP
cord-005603-kjcbbgse	8	13	criteria	criterion	NNS
cord-005603-kjcbbgse	8	14	met	meet	VBD
cord-005603-kjcbbgse	8	15	,	,	,
cord-005603-kjcbbgse	8	16	and	and	CC
cord-005603-kjcbbgse	8	17	with	with	IN
cord-005603-kjcbbgse	8	18	increasing	increase	VBG
cord-005603-kjcbbgse	8	19	severity	severity	NN
cord-005603-kjcbbgse	8	20	of	of	IN
cord-005603-kjcbbgse	8	21	the	the	DT
cord-005603-kjcbbgse	8	22	septic	septic	JJ
cord-005603-kjcbbgse	8	23	syndromes	syndrome	NNS
cord-005603-kjcbbgse	8	24	.	.	.
cord-005603-kjcbbgse	9	1	About	about	RB
cord-005603-kjcbbgse	9	2	one	one	CD
cord-005603-kjcbbgse	9	3	-	-	HYPH
cord-005603-kjcbbgse	9	4	third	third	NN
cord-005603-kjcbbgse	9	5	of	of	IN
cord-005603-kjcbbgse	9	6	patients	patient	NNS
cord-005603-kjcbbgse	9	7	with	with	IN
cord-005603-kjcbbgse	9	8	SIRS	SIRS	NNP
cord-005603-kjcbbgse	9	9	have	have	VBP
cord-005603-kjcbbgse	9	10	or	or	CC
cord-005603-kjcbbgse	9	11	evolve	evolve	VB
cord-005603-kjcbbgse	9	12	to	to	TO
cord-005603-kjcbbgse	9	13	sepsis	sepsis	VB
cord-005603-kjcbbgse	9	14	.	.	.
cord-005603-kjcbbgse	10	1	Sepsis	sepsis	NN
cord-005603-kjcbbgse	10	2	may	may	MD
cord-005603-kjcbbgse	10	3	occur	occur	VB
cord-005603-kjcbbgse	10	4	in	in	IN
cord-005603-kjcbbgse	10	5	approximately	approximately	RB
cord-005603-kjcbbgse	10	6	25	25	CD
cord-005603-kjcbbgse	10	7	%	%	NN
cord-005603-kjcbbgse	10	8	of	of	IN
cord-005603-kjcbbgse	10	9	ICU	ICU	NNP
cord-005603-kjcbbgse	10	10	patients	patient	NNS
cord-005603-kjcbbgse	10	11	,	,	,
cord-005603-kjcbbgse	10	12	and	and	CC
cord-005603-kjcbbgse	10	13	bacteraemic	bacteraemic	NNP
cord-005603-kjcbbgse	10	14	sepsis	sepsis	NN
cord-005603-kjcbbgse	10	15	in	in	IN
cord-005603-kjcbbgse	10	16	10	10	CD
cord-005603-kjcbbgse	10	17	%	%	NN
cord-005603-kjcbbgse	10	18	.	.	.
cord-005603-kjcbbgse	11	1	In	in	IN
cord-005603-kjcbbgse	11	2	such	such	JJ
cord-005603-kjcbbgse	11	3	patients	patient	NNS
cord-005603-kjcbbgse	11	4	,	,	,
cord-005603-kjcbbgse	11	5	sepsis	sepsis	NN
cord-005603-kjcbbgse	11	6	evolves	evolve	VBZ
cord-005603-kjcbbgse	11	7	to	to	IN
cord-005603-kjcbbgse	11	8	severe	severe	JJ
cord-005603-kjcbbgse	11	9	sepsis	sepsis	NN
cord-005603-kjcbbgse	11	10	in	in	IN
cord-005603-kjcbbgse	11	11	>	>	$
cord-005603-kjcbbgse	11	12	50	50	CD
cord-005603-kjcbbgse	11	13	%	%	NN
cord-005603-kjcbbgse	11	14	of	of	IN
cord-005603-kjcbbgse	11	15	cases	case	NNS
cord-005603-kjcbbgse	11	16	,	,	,
cord-005603-kjcbbgse	11	17	whereas	whereas	IN
cord-005603-kjcbbgse	11	18	evolution	evolution	NN
cord-005603-kjcbbgse	11	19	to	to	IN
cord-005603-kjcbbgse	11	20	severe	severe	JJ
cord-005603-kjcbbgse	11	21	sepsis	sepsis	NN
cord-005603-kjcbbgse	11	22	in	in	IN
cord-005603-kjcbbgse	11	23	non	non	JJ
cord-005603-kjcbbgse	11	24	-	-	JJ
cord-005603-kjcbbgse	11	25	ICU	icu	JJ
cord-005603-kjcbbgse	11	26	patients	patient	NNS
cord-005603-kjcbbgse	11	27	is	be	VBZ
cord-005603-kjcbbgse	11	28	about	about	RB
cord-005603-kjcbbgse	11	29	25	25	CD
cord-005603-kjcbbgse	11	30	%	%	NN
cord-005603-kjcbbgse	11	31	.	.	.
cord-005603-kjcbbgse	12	1	Severe	severe	JJ
cord-005603-kjcbbgse	12	2	sepsis	sepsis	NN
cord-005603-kjcbbgse	12	3	and	and	CC
cord-005603-kjcbbgse	12	4	septic	septic	JJ
cord-005603-kjcbbgse	12	5	shock	shock	NN
cord-005603-kjcbbgse	12	6	occur	occur	VBP
cord-005603-kjcbbgse	12	7	in	in	IN
cord-005603-kjcbbgse	12	8	2	2	CD
cord-005603-kjcbbgse	12	9	%	%	NN
cord-005603-kjcbbgse	12	10	–	–	:
cord-005603-kjcbbgse	12	11	3	3	CD
cord-005603-kjcbbgse	12	12	%	%	NN
cord-005603-kjcbbgse	12	13	of	of	IN
cord-005603-kjcbbgse	12	14	ward	ward	NN
cord-005603-kjcbbgse	12	15	patients	patient	NNS
cord-005603-kjcbbgse	12	16	and	and	CC
cord-005603-kjcbbgse	12	17	10	10	CD
cord-005603-kjcbbgse	12	18	%	%	NN
cord-005603-kjcbbgse	12	19	–	–	:
cord-005603-kjcbbgse	12	20	15	15	CD
cord-005603-kjcbbgse	12	21	%	%	NN
cord-005603-kjcbbgse	12	22	or	or	CC
cord-005603-kjcbbgse	12	23	more	more	JJR
cord-005603-kjcbbgse	12	24	ICU	ICU	NNP
cord-005603-kjcbbgse	12	25	patients	patient	NNS
cord-005603-kjcbbgse	12	26	,	,	,
cord-005603-kjcbbgse	12	27	depending	depend	VBG
cord-005603-kjcbbgse	12	28	on	on	IN
cord-005603-kjcbbgse	12	29	the	the	DT
cord-005603-kjcbbgse	12	30	case	case	NN
cord-005603-kjcbbgse	12	31	-	-	HYPH
cord-005603-kjcbbgse	12	32	mix	mix	NN
cord-005603-kjcbbgse	12	33	;	;	:
cord-005603-kjcbbgse	12	34	25	25	CD
cord-005603-kjcbbgse	12	35	%	%	NN
cord-005603-kjcbbgse	12	36	of	of	IN
cord-005603-kjcbbgse	12	37	patients	patient	NNS
cord-005603-kjcbbgse	12	38	with	with	IN
cord-005603-kjcbbgse	12	39	severe	severe	JJ
cord-005603-kjcbbgse	12	40	sepsis	sepsis	NN
cord-005603-kjcbbgse	12	41	have	have	VBP
cord-005603-kjcbbgse	12	42	shock	shock	NN
cord-005603-kjcbbgse	12	43	.	.	.
cord-005603-kjcbbgse	13	1	There	there	EX
cord-005603-kjcbbgse	13	2	is	be	VBZ
cord-005603-kjcbbgse	13	3	a	a	DT
cord-005603-kjcbbgse	13	4	graded	grade	VBN
cord-005603-kjcbbgse	13	5	severity	severity	NN
cord-005603-kjcbbgse	13	6	from	from	IN
cord-005603-kjcbbgse	13	7	SIRS	SIRS	NNP
cord-005603-kjcbbgse	13	8	to	to	IN
cord-005603-kjcbbgse	13	9	sepsis	sepsis	NN
cord-005603-kjcbbgse	13	10	,	,	,
cord-005603-kjcbbgse	13	11	severe	severe	JJ
cord-005603-kjcbbgse	13	12	sepsis	sepsis	NN
cord-005603-kjcbbgse	13	13	and	and	CC
cord-005603-kjcbbgse	13	14	septic	septic	JJ
cord-005603-kjcbbgse	13	15	shock	shock	NN
cord-005603-kjcbbgse	13	16	,	,	,
cord-005603-kjcbbgse	13	17	with	with	IN
cord-005603-kjcbbgse	13	18	an	an	DT
cord-005603-kjcbbgse	13	19	associated	associated	JJ
cord-005603-kjcbbgse	13	20	28-d	28-d	CD
cord-005603-kjcbbgse	13	21	mortality	mortality	NN
cord-005603-kjcbbgse	13	22	of	of	IN
cord-005603-kjcbbgse	13	23	approximately	approximately	RB
cord-005603-kjcbbgse	13	24	10	10	CD
cord-005603-kjcbbgse	13	25	%	%	NN
cord-005603-kjcbbgse	13	26	,	,	,
cord-005603-kjcbbgse	13	27	20	20	CD
cord-005603-kjcbbgse	13	28	%	%	NN
cord-005603-kjcbbgse	13	29	,	,	,
cord-005603-kjcbbgse	13	30	20	20	CD
cord-005603-kjcbbgse	13	31	%	%	NN
cord-005603-kjcbbgse	13	32	–	–	:
cord-005603-kjcbbgse	13	33	40	40	CD
cord-005603-kjcbbgse	13	34	%	%	NN
cord-005603-kjcbbgse	13	35	,	,	,
cord-005603-kjcbbgse	13	36	and	and	CC
cord-005603-kjcbbgse	13	37	40	40	CD
cord-005603-kjcbbgse	13	38	%	%	NN
cord-005603-kjcbbgse	13	39	–	–	:
cord-005603-kjcbbgse	13	40	60	60	CD
cord-005603-kjcbbgse	13	41	%	%	NN
cord-005603-kjcbbgse	13	42	,	,	,
cord-005603-kjcbbgse	13	43	respectively	respectively	RB
cord-005603-kjcbbgse	13	44	.	.	.
cord-005603-kjcbbgse	14	1	Mortality	mortality	NN
cord-005603-kjcbbgse	14	2	rates	rate	NNS
cord-005603-kjcbbgse	14	3	are	be	VBP
cord-005603-kjcbbgse	14	4	similar	similar	JJ
cord-005603-kjcbbgse	14	5	within	within	IN
cord-005603-kjcbbgse	14	6	each	each	DT
cord-005603-kjcbbgse	14	7	stage	stage	NN
cord-005603-kjcbbgse	14	8	,	,	,
cord-005603-kjcbbgse	14	9	whether	whether	IN
cord-005603-kjcbbgse	14	10	infection	infection	NN
cord-005603-kjcbbgse	14	11	is	be	VBZ
cord-005603-kjcbbgse	14	12	documented	document	VBN
cord-005603-kjcbbgse	14	13	or	or	CC
cord-005603-kjcbbgse	14	14	not	not	RB
cord-005603-kjcbbgse	14	15	,	,	,
cord-005603-kjcbbgse	14	16	and	and	CC
cord-005603-kjcbbgse	14	17	microbiological	microbiological	JJ
cord-005603-kjcbbgse	14	18	characteristics	characteristic	NNS
cord-005603-kjcbbgse	14	19	of	of	IN
cord-005603-kjcbbgse	14	20	infection	infection	NN
cord-005603-kjcbbgse	14	21	do	do	VBP
cord-005603-kjcbbgse	14	22	not	not	RB
cord-005603-kjcbbgse	14	23	substantially	substantially	RB
cord-005603-kjcbbgse	14	24	influence	influence	VB
cord-005603-kjcbbgse	14	25	outcome	outcome	NN
cord-005603-kjcbbgse	14	26	,	,	,
cord-005603-kjcbbgse	14	27	although	although	IN
cord-005603-kjcbbgse	14	28	the	the	DT
cord-005603-kjcbbgse	14	29	source	source	NN
cord-005603-kjcbbgse	14	30	of	of	IN
cord-005603-kjcbbgse	14	31	infection	infection	NN
cord-005603-kjcbbgse	14	32	does	do	VBZ
cord-005603-kjcbbgse	14	33	.	.	.
cord-005603-kjcbbgse	15	1	While	while	IN
cord-005603-kjcbbgse	15	2	about	about	RB
cord-005603-kjcbbgse	15	3	three	three	CD
cord-005603-kjcbbgse	15	4	of	of	IN
cord-005603-kjcbbgse	15	5	four	four	CD
cord-005603-kjcbbgse	15	6	deaths	death	NNS
cord-005603-kjcbbgse	15	7	occur	occur	VBP
cord-005603-kjcbbgse	15	8	during	during	IN
cord-005603-kjcbbgse	15	9	the	the	DT
cord-005603-kjcbbgse	15	10	first	first	JJ
cord-005603-kjcbbgse	15	11	months	month	NNS
cord-005603-kjcbbgse	15	12	after	after	IN
cord-005603-kjcbbgse	15	13	sepsis	sepsis	NN
cord-005603-kjcbbgse	15	14	,	,	,
cord-005603-kjcbbgse	15	15	the	the	DT
cord-005603-kjcbbgse	15	16	septic	septic	JJ
cord-005603-kjcbbgse	15	17	syndromes	syndrome	NNS
cord-005603-kjcbbgse	15	18	significantly	significantly	RB
cord-005603-kjcbbgse	15	19	impact	impact	VBP
cord-005603-kjcbbgse	15	20	on	on	IN
cord-005603-kjcbbgse	15	21	long	long	JJ
cord-005603-kjcbbgse	15	22	-	-	HYPH
cord-005603-kjcbbgse	15	23	term	term	NN
cord-005603-kjcbbgse	15	24	outcome	outcome	NN
cord-005603-kjcbbgse	15	25	,	,	,
cord-005603-kjcbbgse	15	26	with	with	IN
cord-005603-kjcbbgse	15	27	an	an	DT
cord-005603-kjcbbgse	15	28	estimated	estimate	VBN
cord-005603-kjcbbgse	15	29	50	50	CD
cord-005603-kjcbbgse	15	30	%	%	NN
cord-005603-kjcbbgse	15	31	reduction	reduction	NN
cord-005603-kjcbbgse	15	32	of	of	IN
cord-005603-kjcbbgse	15	33	life	life	NN
cord-005603-kjcbbgse	15	34	expectancy	expectancy	NN
cord-005603-kjcbbgse	15	35	over	over	IN
cord-005603-kjcbbgse	15	36	the	the	DT
cord-005603-kjcbbgse	15	37	following	following	JJ
cord-005603-kjcbbgse	15	38	five	five	CD
cord-005603-kjcbbgse	15	39	years	year	NNS
cord-005603-kjcbbgse	15	40	.	.	.
cord-005603-kjcbbgse	16	1	The	the	DT
cord-005603-kjcbbgse	16	2	major	major	JJ
cord-005603-kjcbbgse	16	3	determinants	determinant	NNS
cord-005603-kjcbbgse	16	4	of	of	IN
cord-005603-kjcbbgse	16	5	outcome	outcome	NN
cord-005603-kjcbbgse	16	6	,	,	,
cord-005603-kjcbbgse	16	7	both	both	CC
cord-005603-kjcbbgse	16	8	short	short	JJ
cord-005603-kjcbbgse	16	9	-	-	HYPH
cord-005603-kjcbbgse	16	10	term	term	NN
cord-005603-kjcbbgse	16	11	and	and	CC
cord-005603-kjcbbgse	16	12	long	long	JJ
cord-005603-kjcbbgse	16	13	-	-	HYPH
cord-005603-kjcbbgse	16	14	term	term	NN
cord-005603-kjcbbgse	16	15	,	,	,
cord-005603-kjcbbgse	16	16	of	of	IN
cord-005603-kjcbbgse	16	17	patients	patient	NNS
cord-005603-kjcbbgse	16	18	with	with	IN
cord-005603-kjcbbgse	16	19	sepsis	sepsis	NN
cord-005603-kjcbbgse	16	20	are	be	VBP
cord-005603-kjcbbgse	16	21	the	the	DT
cord-005603-kjcbbgse	16	22	severity	severity	NN
cord-005603-kjcbbgse	16	23	of	of	IN
cord-005603-kjcbbgse	16	24	underlying	underlie	VBG
cord-005603-kjcbbgse	16	25	diseases	disease	NNS
cord-005603-kjcbbgse	16	26	and	and	CC
cord-005603-kjcbbgse	16	27	comorbidities	comorbiditie	NNS
cord-005603-kjcbbgse	16	28	,	,	,
cord-005603-kjcbbgse	16	29	the	the	DT
cord-005603-kjcbbgse	16	30	presence	presence	NN
cord-005603-kjcbbgse	16	31	of	of	IN
cord-005603-kjcbbgse	16	32	shock	shock	NN
cord-005603-kjcbbgse	16	33	and	and	CC
cord-005603-kjcbbgse	16	34	organ	organ	NN
cord-005603-kjcbbgse	16	35	failures	failure	NNS
cord-005603-kjcbbgse	16	36	at	at	IN
cord-005603-kjcbbgse	16	37	onset	onset	NN
cord-005603-kjcbbgse	16	38	of	of	IN
cord-005603-kjcbbgse	16	39	sepsis	sepsis	NN
cord-005603-kjcbbgse	16	40	or	or	CC
cord-005603-kjcbbgse	16	41	evolving	evolve	VBG
cord-005603-kjcbbgse	16	42	thereafter	thereafter	RB
cord-005603-kjcbbgse	16	43	.	.	.
cord-005603-kjcbbgse	17	1	It	-PRON-	PRP
cord-005603-kjcbbgse	17	2	has	have	VBZ
cord-005603-kjcbbgse	17	3	been	be	VBN
cord-005603-kjcbbgse	17	4	estimated	estimate	VBN
cord-005603-kjcbbgse	17	5	that	that	IN
cord-005603-kjcbbgse	17	6	two	two	CD
cord-005603-kjcbbgse	17	7	-	-	HYPH
cord-005603-kjcbbgse	17	8	thirds	third	NNS
cord-005603-kjcbbgse	17	9	of	of	IN
cord-005603-kjcbbgse	17	10	the	the	DT
cord-005603-kjcbbgse	17	11	overall	overall	JJ
cord-005603-kjcbbgse	17	12	mortality	mortality	NN
cord-005603-kjcbbgse	17	13	can	can	MD
cord-005603-kjcbbgse	17	14	be	be	VB
cord-005603-kjcbbgse	17	15	attributed	attribute	VBN
cord-005603-kjcbbgse	17	16	to	to	IN
cord-005603-kjcbbgse	17	17	sepsis.¶Conclusions	sepsis.¶conclusion	NNS
cord-005603-kjcbbgse	17	18	:	:	:
cord-005603-kjcbbgse	18	1	The	the	DT
cord-005603-kjcbbgse	18	2	prevalence	prevalence	NN
cord-005603-kjcbbgse	18	3	of	of	IN
cord-005603-kjcbbgse	18	4	sepsis	sepsis	NN
cord-005603-kjcbbgse	18	5	in	in	IN
cord-005603-kjcbbgse	18	6	ICU	ICU	NNP
cord-005603-kjcbbgse	18	7	patients	patient	NNS
cord-005603-kjcbbgse	18	8	is	be	VBZ
cord-005603-kjcbbgse	18	9	very	very	RB
cord-005603-kjcbbgse	18	10	high	high	JJ
cord-005603-kjcbbgse	18	11	,	,	,
cord-005603-kjcbbgse	18	12	and	and	CC
cord-005603-kjcbbgse	18	13	most	most	JJS
cord-005603-kjcbbgse	18	14	patients	patient	NNS
cord-005603-kjcbbgse	18	15	have	have	VBP
cord-005603-kjcbbgse	18	16	clinically	clinically	RB
cord-005603-kjcbbgse	18	17	or	or	CC
cord-005603-kjcbbgse	18	18	microbiologically	microbiologically	RB
cord-005603-kjcbbgse	18	19	documented	document	VBN
cord-005603-kjcbbgse	18	20	infection	infection	NN
cord-005603-kjcbbgse	18	21	,	,	,
cord-005603-kjcbbgse	18	22	except	except	IN
cord-005603-kjcbbgse	18	23	in	in	IN
cord-005603-kjcbbgse	18	24	specific	specific	JJ
cord-005603-kjcbbgse	18	25	subset	subset	NN
cord-005603-kjcbbgse	18	26	of	of	IN
cord-005603-kjcbbgse	18	27	patients	patient	NNS
cord-005603-kjcbbgse	18	28	.	.	.
cord-005603-kjcbbgse	19	1	The	the	DT
cord-005603-kjcbbgse	19	2	prognosis	prognosis	NN
cord-005603-kjcbbgse	19	3	of	of	IN
cord-005603-kjcbbgse	19	4	septic	septic	JJ
cord-005603-kjcbbgse	19	5	syndromes	syndrome	NNS
cord-005603-kjcbbgse	19	6	is	be	VBZ
cord-005603-kjcbbgse	19	7	related	relate	VBN
cord-005603-kjcbbgse	19	8	to	to	IN
cord-005603-kjcbbgse	19	9	underlying	underlie	VBG
cord-005603-kjcbbgse	19	10	diseases	disease	NNS
cord-005603-kjcbbgse	19	11	and	and	CC
cord-005603-kjcbbgse	19	12	the	the	DT
cord-005603-kjcbbgse	19	13	severity	severity	NN
cord-005603-kjcbbgse	19	14	of	of	IN
cord-005603-kjcbbgse	19	15	the	the	DT
cord-005603-kjcbbgse	19	16	inflammatory	inflammatory	JJ
cord-005603-kjcbbgse	19	17	response	response	NN
cord-005603-kjcbbgse	19	18	and	and	CC
cord-005603-kjcbbgse	19	19	its	-PRON-	PRP$
cord-005603-kjcbbgse	19	20	sequelae	sequela	NNS
cord-005603-kjcbbgse	19	21	,	,	,
cord-005603-kjcbbgse	19	22	reflected	reflect	VBN
cord-005603-kjcbbgse	19	23	in	in	IN
cord-005603-kjcbbgse	19	24	shock	shock	NN
cord-005603-kjcbbgse	19	25	and	and	CC
cord-005603-kjcbbgse	19	26	organ	organ	NN
cord-005603-kjcbbgse	19	27	dysfunction	dysfunction	NN
cord-005603-kjcbbgse	19	28	/	/	SYM
cord-005603-kjcbbgse	19	29	failures	failure	NNS
cord-005603-kjcbbgse	19	30	.	.	.
cord-005603-kjcbbgse	20	1	Abstract	Abstract	NNP
cord-005603-kjcbbgse	20	2	Objective	Objective	NNP
cord-005603-kjcbbgse	20	3	:	:	:
cord-005603-kjcbbgse	20	4	To	to	TO
cord-005603-kjcbbgse	20	5	examine	examine	VB
cord-005603-kjcbbgse	20	6	the	the	DT
cord-005603-kjcbbgse	20	7	incidence	incidence	NN
cord-005603-kjcbbgse	20	8	,	,	,
cord-005603-kjcbbgse	20	9	risk	risk	NN
cord-005603-kjcbbgse	20	10	factors	factor	NNS
cord-005603-kjcbbgse	20	11	,	,	,
cord-005603-kjcbbgse	20	12	aetiologies	aetiology	NNS
cord-005603-kjcbbgse	20	13	and	and	CC
cord-005603-kjcbbgse	20	14	outcome	outcome	NN
cord-005603-kjcbbgse	20	15	of	of	IN
cord-005603-kjcbbgse	20	16	the	the	DT
cord-005603-kjcbbgse	20	17	various	various	JJ
cord-005603-kjcbbgse	20	18	forms	form	NNS
cord-005603-kjcbbgse	20	19	of	of	IN
cord-005603-kjcbbgse	20	20	the	the	DT
cord-005603-kjcbbgse	20	21	septic	septic	JJ
cord-005603-kjcbbgse	20	22	syndromes	syndrome	NNS
cord-005603-kjcbbgse	20	23	(	(	-LRB-
cord-005603-kjcbbgse	20	24	the	the	DT
cord-005603-kjcbbgse	20	25	systemic	systemic	JJ
cord-005603-kjcbbgse	20	26	inflammatory	inflammatory	JJ
cord-005603-kjcbbgse	20	27	response	response	NN
cord-005603-kjcbbgse	20	28	syndrome	syndrome	NN
cord-005603-kjcbbgse	20	29	[	[	-LRB-
cord-005603-kjcbbgse	20	30	SIRS	sirs	UH
cord-005603-kjcbbgse	20	31	]	]	-RRB-
cord-005603-kjcbbgse	20	32	sepsis	sepsis	NN
cord-005603-kjcbbgse	20	33	,	,	,
cord-005603-kjcbbgse	20	34	severe	severe	JJ
cord-005603-kjcbbgse	20	35	sepsis	sepsis	NN
cord-005603-kjcbbgse	20	36	,	,	,
cord-005603-kjcbbgse	20	37	and	and	CC
cord-005603-kjcbbgse	20	38	septic	septic	JJ
cord-005603-kjcbbgse	20	39	shock	shock	NN
cord-005603-kjcbbgse	20	40	)	)	-RRB-
cord-005603-kjcbbgse	20	41	and	and	CC
cord-005603-kjcbbgse	20	42	their	-PRON-	PRP$
cord-005603-kjcbbgse	20	43	relationships	relationship	NNS
cord-005603-kjcbbgse	20	44	with	with	IN
cord-005603-kjcbbgse	20	45	infection	infection	NN
cord-005603-kjcbbgse	20	46	.	.	.
cord-005603-kjcbbgse	21	1	Design	design	NN
cord-005603-kjcbbgse	21	2	:	:	:
cord-005603-kjcbbgse	21	3	Review	Review	NNP
cord-005603-kjcbbgse	21	4	of	of	IN
cord-005603-kjcbbgse	21	5	published	publish	VBN
cord-005603-kjcbbgse	21	6	cohort	cohort	NN
cord-005603-kjcbbgse	21	7	studies	study	NNS
cord-005603-kjcbbgse	21	8	examining	examine	VBG
cord-005603-kjcbbgse	21	9	the	the	DT
cord-005603-kjcbbgse	21	10	epidemiology	epidemiology	NN
cord-005603-kjcbbgse	21	11	of	of	IN
cord-005603-kjcbbgse	21	12	the	the	DT
cord-005603-kjcbbgse	21	13	septic	septic	JJ
cord-005603-kjcbbgse	21	14	syndromes	syndrome	NNS
cord-005603-kjcbbgse	21	15	,	,	,
cord-005603-kjcbbgse	21	16	with	with	IN
cord-005603-kjcbbgse	21	17	emphasis	emphasis	NN
cord-005603-kjcbbgse	21	18	on	on	IN
cord-005603-kjcbbgse	21	19	intensive	intensive	JJ
cord-005603-kjcbbgse	21	20	care	care	NN
cord-005603-kjcbbgse	21	21	unit	unit	NN
cord-005603-kjcbbgse	21	22	(	(	-LRB-
cord-005603-kjcbbgse	21	23	ICU	ICU	NNP
cord-005603-kjcbbgse	21	24	)	)	-RRB-
cord-005603-kjcbbgse	21	25	patients	patient	NNS
cord-005603-kjcbbgse	21	26	.	.	.
cord-005603-kjcbbgse	22	1	Results	result	NNS
cord-005603-kjcbbgse	22	2	:	:	:
cord-005603-kjcbbgse	23	1	The	the	DT
cord-005603-kjcbbgse	23	2	prevalence	prevalence	NN
cord-005603-kjcbbgse	23	3	of	of	IN
cord-005603-kjcbbgse	23	4	SIRS	SIRS	NNP
cord-005603-kjcbbgse	23	5	is	be	VBZ
cord-005603-kjcbbgse	23	6	very	very	RB
cord-005603-kjcbbgse	23	7	high	high	JJ
cord-005603-kjcbbgse	23	8	,	,	,
cord-005603-kjcbbgse	23	9	affecting	affect	VBG
cord-005603-kjcbbgse	23	10	one	one	CD
cord-005603-kjcbbgse	23	11	-	-	HYPH
cord-005603-kjcbbgse	23	12	third	third	NN
cord-005603-kjcbbgse	23	13	of	of	IN
cord-005603-kjcbbgse	23	14	all	all	DT
cord-005603-kjcbbgse	23	15	in	in	IN
cord-005603-kjcbbgse	23	16	-	-	HYPH
cord-005603-kjcbbgse	23	17	hospital	hospital	NN
cord-005603-kjcbbgse	23	18	patients	patient	NNS
cord-005603-kjcbbgse	23	19	,	,	,
cord-005603-kjcbbgse	23	20	and	and	CC
cord-005603-kjcbbgse	23	21	>	>	XX
cord-005603-kjcbbgse	23	22	50	50	CD
cord-005603-kjcbbgse	23	23	%	%	NN
cord-005603-kjcbbgse	23	24	of	of	IN
cord-005603-kjcbbgse	23	25	all	all	DT
cord-005603-kjcbbgse	23	26	ICU	ICU	NNP
cord-005603-kjcbbgse	23	27	patients	patient	NNS
cord-005603-kjcbbgse	23	28	;	;	:
cord-005603-kjcbbgse	23	29	in	in	IN
cord-005603-kjcbbgse	23	30	surgical	surgical	JJ
cord-005603-kjcbbgse	23	31	ICU	ICU	NNP
cord-005603-kjcbbgse	23	32	patients	patient	NNS
cord-005603-kjcbbgse	23	33	,	,	,
cord-005603-kjcbbgse	23	34	SIRS	SIRS	NNP
cord-005603-kjcbbgse	23	35	occurs	occur	VBZ
cord-005603-kjcbbgse	23	36	in	in	IN
cord-005603-kjcbbgse	23	37	>	>	$
cord-005603-kjcbbgse	23	38	80	80	CD
cord-005603-kjcbbgse	23	39	%	%	NN
cord-005603-kjcbbgse	23	40	patients	patient	NNS
cord-005603-kjcbbgse	23	41	.	.	.
cord-005603-kjcbbgse	24	1	Trauma	trauma	NN
cord-005603-kjcbbgse	24	2	patients	patient	NNS
cord-005603-kjcbbgse	24	3	are	be	VBP
cord-005603-kjcbbgse	24	4	at	at	IN
cord-005603-kjcbbgse	24	5	particularly	particularly	RB
cord-005603-kjcbbgse	24	6	high	high	JJ
cord-005603-kjcbbgse	24	7	risk	risk	NN
cord-005603-kjcbbgse	24	8	of	of	IN
cord-005603-kjcbbgse	24	9	SIRS	SIRS	NNP
cord-005603-kjcbbgse	24	10	,	,	,
cord-005603-kjcbbgse	24	11	and	and	CC
cord-005603-kjcbbgse	24	12	most	most	JJS
cord-005603-kjcbbgse	24	13	these	these	DT
cord-005603-kjcbbgse	24	14	patients	patient	NNS
cord-005603-kjcbbgse	24	15	do	do	VBP
cord-005603-kjcbbgse	24	16	not	not	RB
cord-005603-kjcbbgse	24	17	have	have	VB
cord-005603-kjcbbgse	24	18	infection	infection	NN
cord-005603-kjcbbgse	24	19	documented	document	VBN
cord-005603-kjcbbgse	24	20	.	.	.
cord-005603-kjcbbgse	25	1	The	the	DT
cord-005603-kjcbbgse	25	2	prevalence	prevalence	NN
cord-005603-kjcbbgse	25	3	of	of	IN
cord-005603-kjcbbgse	25	4	infection	infection	NN
cord-005603-kjcbbgse	25	5	and	and	CC
cord-005603-kjcbbgse	25	6	bacteraemia	bacteraemia	NN
cord-005603-kjcbbgse	25	7	increases	increase	VBZ
cord-005603-kjcbbgse	25	8	with	with	IN
cord-005603-kjcbbgse	25	9	the	the	DT
cord-005603-kjcbbgse	25	10	number	number	NN
cord-005603-kjcbbgse	25	11	of	of	IN
cord-005603-kjcbbgse	25	12	SIRS	SIRS	NNP
cord-005603-kjcbbgse	25	13	criteria	criterion	NNS
cord-005603-kjcbbgse	25	14	met	meet	VBD
cord-005603-kjcbbgse	25	15	,	,	,
cord-005603-kjcbbgse	25	16	and	and	CC
cord-005603-kjcbbgse	25	17	with	with	IN
cord-005603-kjcbbgse	25	18	increasing	increase	VBG
cord-005603-kjcbbgse	25	19	severity	severity	NN
cord-005603-kjcbbgse	25	20	of	of	IN
cord-005603-kjcbbgse	25	21	the	the	DT
cord-005603-kjcbbgse	25	22	septic	septic	JJ
cord-005603-kjcbbgse	25	23	syndromes	syndrome	NNS
cord-005603-kjcbbgse	25	24	.	.	.
cord-005603-kjcbbgse	26	1	About	about	IN
cord-005603-kjcbbgse	26	2	onethird	onethird	NN
cord-005603-kjcbbgse	26	3	of	of	IN
cord-005603-kjcbbgse	26	4	patients	patient	NNS
cord-005603-kjcbbgse	26	5	with	with	IN
cord-005603-kjcbbgse	26	6	SIRS	SIRS	NNP
cord-005603-kjcbbgse	26	7	have	have	VBP
cord-005603-kjcbbgse	26	8	or	or	CC
cord-005603-kjcbbgse	26	9	evolve	evolve	VB
cord-005603-kjcbbgse	26	10	to	to	TO
cord-005603-kjcbbgse	26	11	sepsis	sepsis	VB
cord-005603-kjcbbgse	26	12	.	.	.
cord-005603-kjcbbgse	27	1	Sepsis	sepsis	NN
cord-005603-kjcbbgse	27	2	may	may	MD
cord-005603-kjcbbgse	27	3	occur	occur	VB
cord-005603-kjcbbgse	27	4	in	in	IN
cord-005603-kjcbbgse	27	5	approximately	approximately	RB
cord-005603-kjcbbgse	27	6	25	25	CD
cord-005603-kjcbbgse	27	7	%	%	NN
cord-005603-kjcbbgse	27	8	of	of	IN
cord-005603-kjcbbgse	27	9	ICU	ICU	NNP
cord-005603-kjcbbgse	27	10	patients	patient	NNS
cord-005603-kjcbbgse	27	11	,	,	,
cord-005603-kjcbbgse	27	12	and	and	CC
cord-005603-kjcbbgse	27	13	bacteraemic	bacteraemic	NNP
cord-005603-kjcbbgse	27	14	sepsis	sepsis	NN
cord-005603-kjcbbgse	27	15	in	in	IN
cord-005603-kjcbbgse	27	16	10	10	CD
cord-005603-kjcbbgse	27	17	%	%	NN
cord-005603-kjcbbgse	27	18	.	.	.
cord-005603-kjcbbgse	28	1	In	in	IN
cord-005603-kjcbbgse	28	2	such	such	JJ
cord-005603-kjcbbgse	28	3	patients	patient	NNS
cord-005603-kjcbbgse	28	4	,	,	,
cord-005603-kjcbbgse	28	5	sepsis	sepsis	NN
cord-005603-kjcbbgse	28	6	evolves	evolve	VBZ
cord-005603-kjcbbgse	28	7	to	to	IN
cord-005603-kjcbbgse	28	8	severe	severe	JJ
cord-005603-kjcbbgse	28	9	sepsis	sepsis	NN
cord-005603-kjcbbgse	28	10	in	in	IN
cord-005603-kjcbbgse	28	11	>	>	$
cord-005603-kjcbbgse	28	12	50	50	CD
cord-005603-kjcbbgse	28	13	%	%	NN
cord-005603-kjcbbgse	28	14	of	of	IN
cord-005603-kjcbbgse	28	15	cases	case	NNS
cord-005603-kjcbbgse	28	16	,	,	,
cord-005603-kjcbbgse	28	17	whereas	whereas	IN
cord-005603-kjcbbgse	28	18	evolution	evolution	NN
cord-005603-kjcbbgse	28	19	to	to	IN
cord-005603-kjcbbgse	28	20	severe	severe	JJ
cord-005603-kjcbbgse	28	21	sepsis	sepsis	NN
cord-005603-kjcbbgse	28	22	in	in	IN
cord-005603-kjcbbgse	28	23	non	non	JJ
cord-005603-kjcbbgse	28	24	-	-	JJ
cord-005603-kjcbbgse	28	25	ICU	icu	JJ
cord-005603-kjcbbgse	28	26	patients	patient	NNS
cord-005603-kjcbbgse	28	27	is	be	VBZ
cord-005603-kjcbbgse	28	28	about	about	RB
cord-005603-kjcbbgse	28	29	25	25	CD
cord-005603-kjcbbgse	28	30	%	%	NN
cord-005603-kjcbbgse	28	31	.	.	.
cord-005603-kjcbbgse	29	1	Severe	severe	JJ
cord-005603-kjcbbgse	29	2	sepsis	sepsis	NN
cord-005603-kjcbbgse	29	3	and	and	CC
cord-005603-kjcbbgse	29	4	septic	septic	JJ
cord-005603-kjcbbgse	29	5	shock	shock	NN
cord-005603-kjcbbgse	29	6	occur	occur	VBP
cord-005603-kjcbbgse	29	7	in	in	IN
cord-005603-kjcbbgse	29	8	2	2	CD
cord-005603-kjcbbgse	29	9	%	%	NN
cord-005603-kjcbbgse	29	10	±3	±3	NNP
cord-005603-kjcbbgse	29	11	%	%	NN
cord-005603-kjcbbgse	29	12	of	of	IN
cord-005603-kjcbbgse	29	13	ward	ward	NN
cord-005603-kjcbbgse	29	14	patients	patient	NNS
cord-005603-kjcbbgse	29	15	and	and	CC
cord-005603-kjcbbgse	29	16	10	10	CD
cord-005603-kjcbbgse	29	17	%	%	NN
cord-005603-kjcbbgse	29	18	±15	±15	NNP
cord-005603-kjcbbgse	29	19	%	%	NN
cord-005603-kjcbbgse	29	20	or	or	CC
cord-005603-kjcbbgse	29	21	more	more	JJR
cord-005603-kjcbbgse	29	22	ICU	ICU	NNP
cord-005603-kjcbbgse	29	23	patients	patient	NNS
cord-005603-kjcbbgse	29	24	,	,	,
cord-005603-kjcbbgse	29	25	depending	depend	VBG
cord-005603-kjcbbgse	29	26	on	on	IN
cord-005603-kjcbbgse	29	27	the	the	DT
cord-005603-kjcbbgse	29	28	case	case	NN
cord-005603-kjcbbgse	29	29	-	-	HYPH
cord-005603-kjcbbgse	29	30	mix	mix	NN
cord-005603-kjcbbgse	29	31	;	;	:
cord-005603-kjcbbgse	29	32	25	25	CD
cord-005603-kjcbbgse	29	33	%	%	NN
cord-005603-kjcbbgse	29	34	of	of	IN
cord-005603-kjcbbgse	29	35	patients	patient	NNS
cord-005603-kjcbbgse	29	36	with	with	IN
cord-005603-kjcbbgse	29	37	severe	severe	JJ
cord-005603-kjcbbgse	29	38	sepsis	sepsis	NN
cord-005603-kjcbbgse	29	39	have	have	VBP
cord-005603-kjcbbgse	29	40	shock	shock	NN
cord-005603-kjcbbgse	29	41	.	.	.
cord-005603-kjcbbgse	30	1	There	there	EX
cord-005603-kjcbbgse	30	2	is	be	VBZ
cord-005603-kjcbbgse	30	3	a	a	DT
cord-005603-kjcbbgse	30	4	graded	grade	VBN
cord-005603-kjcbbgse	30	5	severity	severity	NN
cord-005603-kjcbbgse	30	6	from	from	IN
cord-005603-kjcbbgse	30	7	SIRS	SIRS	NNP
cord-005603-kjcbbgse	30	8	to	to	IN
cord-005603-kjcbbgse	30	9	sepsis	sepsis	NN
cord-005603-kjcbbgse	30	10	,	,	,
cord-005603-kjcbbgse	30	11	severe	severe	JJ
cord-005603-kjcbbgse	30	12	sepsis	sepsis	NN
cord-005603-kjcbbgse	30	13	and	and	CC
cord-005603-kjcbbgse	30	14	septic	septic	JJ
cord-005603-kjcbbgse	30	15	shock	shock	NN
cord-005603-kjcbbgse	30	16	,	,	,
cord-005603-kjcbbgse	30	17	with	with	IN
cord-005603-kjcbbgse	30	18	an	an	DT
cord-005603-kjcbbgse	30	19	associated	associated	JJ
cord-005603-kjcbbgse	30	20	28-d	28-d	CD
cord-005603-kjcbbgse	30	21	mortality	mortality	NN
cord-005603-kjcbbgse	30	22	of	of	IN
cord-005603-kjcbbgse	30	23	approximately	approximately	RB
cord-005603-kjcbbgse	30	24	10	10	CD
cord-005603-kjcbbgse	30	25	%	%	NN
cord-005603-kjcbbgse	30	26	,	,	,
cord-005603-kjcbbgse	30	27	20	20	CD
cord-005603-kjcbbgse	30	28	%	%	NN
cord-005603-kjcbbgse	30	29	,	,	,
cord-005603-kjcbbgse	30	30	20	20	CD
cord-005603-kjcbbgse	30	31	%	%	NN
cord-005603-kjcbbgse	30	32	±40	±40	NNP
cord-005603-kjcbbgse	30	33	%	%	NN
cord-005603-kjcbbgse	30	34	,	,	,
cord-005603-kjcbbgse	30	35	and	and	CC
cord-005603-kjcbbgse	30	36	40	40	CD
cord-005603-kjcbbgse	30	37	%	%	NN
cord-005603-kjcbbgse	30	38	±60	±60	CD
cord-005603-kjcbbgse	30	39	%	%	NN
cord-005603-kjcbbgse	30	40	,	,	,
cord-005603-kjcbbgse	30	41	respectively	respectively	RB
cord-005603-kjcbbgse	30	42	.	.	.
cord-005603-kjcbbgse	31	1	Mortality	mortality	NN
cord-005603-kjcbbgse	31	2	rates	rate	NNS
cord-005603-kjcbbgse	31	3	are	be	VBP
cord-005603-kjcbbgse	31	4	similar	similar	JJ
cord-005603-kjcbbgse	31	5	within	within	IN
cord-005603-kjcbbgse	31	6	each	each	DT
cord-005603-kjcbbgse	31	7	stage	stage	NN
cord-005603-kjcbbgse	31	8	,	,	,
cord-005603-kjcbbgse	31	9	whether	whether	IN
cord-005603-kjcbbgse	31	10	infection	infection	NN
cord-005603-kjcbbgse	31	11	is	be	VBZ
cord-005603-kjcbbgse	31	12	documented	document	VBN
cord-005603-kjcbbgse	31	13	or	or	CC
cord-005603-kjcbbgse	31	14	not	not	RB
cord-005603-kjcbbgse	31	15	,	,	,
cord-005603-kjcbbgse	31	16	and	and	CC
cord-005603-kjcbbgse	31	17	microbiological	microbiological	JJ
cord-005603-kjcbbgse	31	18	characteristics	characteristic	NNS
cord-005603-kjcbbgse	31	19	of	of	IN
cord-005603-kjcbbgse	31	20	infection	infection	NN
cord-005603-kjcbbgse	31	21	do	do	VBP
cord-005603-kjcbbgse	31	22	not	not	RB
cord-005603-kjcbbgse	31	23	substantially	substantially	RB
cord-005603-kjcbbgse	31	24	influence	influence	VB
cord-005603-kjcbbgse	31	25	outcome	outcome	NN
cord-005603-kjcbbgse	31	26	,	,	,
cord-005603-kjcbbgse	31	27	although	although	IN
cord-005603-kjcbbgse	31	28	the	the	DT
cord-005603-kjcbbgse	31	29	source	source	NN
cord-005603-kjcbbgse	31	30	of	of	IN
cord-005603-kjcbbgse	31	31	infection	infection	NN
cord-005603-kjcbbgse	31	32	does	do	VBZ
cord-005603-kjcbbgse	31	33	.	.	.
cord-005603-kjcbbgse	32	1	While	while	IN
cord-005603-kjcbbgse	32	2	about	about	RB
cord-005603-kjcbbgse	32	3	three	three	CD
cord-005603-kjcbbgse	32	4	of	of	IN
cord-005603-kjcbbgse	32	5	four	four	CD
cord-005603-kjcbbgse	32	6	deaths	death	NNS
cord-005603-kjcbbgse	32	7	occur	occur	VBP
cord-005603-kjcbbgse	32	8	during	during	IN
cord-005603-kjcbbgse	32	9	the	the	DT
cord-005603-kjcbbgse	32	10	first	first	JJ
cord-005603-kjcbbgse	32	11	months	month	NNS
cord-005603-kjcbbgse	32	12	after	after	IN
cord-005603-kjcbbgse	32	13	sepsis	sepsis	NN
cord-005603-kjcbbgse	32	14	,	,	,
cord-005603-kjcbbgse	32	15	the	the	DT
cord-005603-kjcbbgse	32	16	septic	septic	JJ
cord-005603-kjcbbgse	32	17	syndromes	syndrome	NNS
cord-005603-kjcbbgse	32	18	significantly	significantly	RB
cord-005603-kjcbbgse	32	19	impact	impact	VBP
cord-005603-kjcbbgse	32	20	on	on	IN
cord-005603-kjcbbgse	32	21	long	long	JJ
cord-005603-kjcbbgse	32	22	-	-	HYPH
cord-005603-kjcbbgse	32	23	term	term	NN
cord-005603-kjcbbgse	32	24	outcome	outcome	NN
cord-005603-kjcbbgse	32	25	,	,	,
cord-005603-kjcbbgse	32	26	with	with	IN
cord-005603-kjcbbgse	32	27	an	an	DT
cord-005603-kjcbbgse	32	28	estimated	estimate	VBN
cord-005603-kjcbbgse	32	29	50	50	CD
cord-005603-kjcbbgse	32	30	%	%	NN
cord-005603-kjcbbgse	32	31	reduction	reduction	NN
cord-005603-kjcbbgse	32	32	of	of	IN
cord-005603-kjcbbgse	32	33	life	life	NN
cord-005603-kjcbbgse	32	34	expectancy	expectancy	NN
cord-005603-kjcbbgse	32	35	over	over	IN
cord-005603-kjcbbgse	32	36	the	the	DT
cord-005603-kjcbbgse	32	37	following	following	JJ
cord-005603-kjcbbgse	32	38	five	five	CD
cord-005603-kjcbbgse	32	39	years	year	NNS
cord-005603-kjcbbgse	32	40	.	.	.
cord-005603-kjcbbgse	33	1	The	the	DT
cord-005603-kjcbbgse	33	2	major	major	JJ
cord-005603-kjcbbgse	33	3	determinants	determinant	NNS
cord-005603-kjcbbgse	33	4	of	of	IN
cord-005603-kjcbbgse	33	5	outcome	outcome	NN
cord-005603-kjcbbgse	33	6	,	,	,
cord-005603-kjcbbgse	33	7	both	both	CC
cord-005603-kjcbbgse	33	8	short	short	JJ
cord-005603-kjcbbgse	33	9	-	-	HYPH
cord-005603-kjcbbgse	33	10	term	term	NN
cord-005603-kjcbbgse	33	11	and	and	CC
cord-005603-kjcbbgse	33	12	long	long	JJ
cord-005603-kjcbbgse	33	13	-	-	HYPH
cord-005603-kjcbbgse	33	14	term	term	NN
cord-005603-kjcbbgse	33	15	,	,	,
cord-005603-kjcbbgse	33	16	of	of	IN
cord-005603-kjcbbgse	33	17	patients	patient	NNS
cord-005603-kjcbbgse	33	18	with	with	IN
cord-005603-kjcbbgse	33	19	sepsis	sepsis	NN
cord-005603-kjcbbgse	33	20	are	be	VBP
cord-005603-kjcbbgse	33	21	the	the	DT
cord-005603-kjcbbgse	33	22	severity	severity	NN
cord-005603-kjcbbgse	33	23	of	of	IN
cord-005603-kjcbbgse	33	24	underlying	underlie	VBG
cord-005603-kjcbbgse	33	25	diseases	disease	NNS
cord-005603-kjcbbgse	33	26	and	and	CC
cord-005603-kjcbbgse	33	27	comorbidities	comorbiditie	NNS
cord-005603-kjcbbgse	33	28	,	,	,
cord-005603-kjcbbgse	33	29	the	the	DT
cord-005603-kjcbbgse	33	30	presence	presence	NN
cord-005603-kjcbbgse	33	31	of	of	IN
cord-005603-kjcbbgse	33	32	shock	shock	NN
cord-005603-kjcbbgse	33	33	and	and	CC
cord-005603-kjcbbgse	33	34	organ	organ	NN
cord-005603-kjcbbgse	33	35	failures	failure	NNS
cord-005603-kjcbbgse	33	36	at	at	IN
cord-005603-kjcbbgse	33	37	onset	onset	NN
cord-005603-kjcbbgse	33	38	of	of	IN
cord-005603-kjcbbgse	33	39	sepsis	sepsis	NN
cord-005603-kjcbbgse	33	40	or	or	CC
cord-005603-kjcbbgse	33	41	evolving	evolve	VBG
cord-005603-kjcbbgse	33	42	thereafter	thereafter	RB
cord-005603-kjcbbgse	33	43	.	.	.
cord-005603-kjcbbgse	34	1	It	-PRON-	PRP
cord-005603-kjcbbgse	34	2	has	have	VBZ
cord-005603-kjcbbgse	34	3	been	be	VBN
cord-005603-kjcbbgse	34	4	estimated	estimate	VBN
cord-005603-kjcbbgse	34	5	that	that	IN
cord-005603-kjcbbgse	34	6	two	two	CD
cord-005603-kjcbbgse	34	7	-	-	HYPH
cord-005603-kjcbbgse	34	8	thirds	third	NNS
cord-005603-kjcbbgse	34	9	of	of	IN
cord-005603-kjcbbgse	34	10	the	the	DT
cord-005603-kjcbbgse	34	11	overall	overall	JJ
cord-005603-kjcbbgse	34	12	mortality	mortality	NN
cord-005603-kjcbbgse	34	13	can	can	MD
cord-005603-kjcbbgse	34	14	be	be	VB
cord-005603-kjcbbgse	34	15	attributed	attribute	VBN
cord-005603-kjcbbgse	34	16	to	to	IN
cord-005603-kjcbbgse	34	17	sepsis	sepsis	NN
cord-005603-kjcbbgse	34	18	.	.	.
cord-005603-kjcbbgse	35	1	Conclusions	conclusion	NNS
cord-005603-kjcbbgse	35	2	:	:	:
cord-005603-kjcbbgse	36	1	The	the	DT
cord-005603-kjcbbgse	36	2	prevalence	prevalence	NN
cord-005603-kjcbbgse	36	3	of	of	IN
cord-005603-kjcbbgse	36	4	sepsis	sepsis	NN
cord-005603-kjcbbgse	36	5	in	in	IN
cord-005603-kjcbbgse	36	6	ICU	ICU	NNP
cord-005603-kjcbbgse	36	7	patients	patient	NNS
cord-005603-kjcbbgse	36	8	is	be	VBZ
cord-005603-kjcbbgse	36	9	very	very	RB
cord-005603-kjcbbgse	36	10	high	high	JJ
cord-005603-kjcbbgse	36	11	,	,	,
cord-005603-kjcbbgse	36	12	and	and	CC
cord-005603-kjcbbgse	36	13	most	most	JJS
cord-005603-kjcbbgse	36	14	patients	patient	NNS
cord-005603-kjcbbgse	36	15	have	have	VBP
cord-005603-kjcbbgse	36	16	clinically	clinically	RB
cord-005603-kjcbbgse	36	17	or	or	CC
cord-005603-kjcbbgse	36	18	microbiologically	microbiologically	RB
cord-005603-kjcbbgse	36	19	documented	document	VBN
cord-005603-kjcbbgse	36	20	infection	infection	NN
cord-005603-kjcbbgse	36	21	,	,	,
cord-005603-kjcbbgse	36	22	except	except	IN
cord-005603-kjcbbgse	36	23	in	in	IN
cord-005603-kjcbbgse	36	24	specific	specific	JJ
cord-005603-kjcbbgse	36	25	subset	subset	NN
cord-005603-kjcbbgse	36	26	of	of	IN
cord-005603-kjcbbgse	36	27	patients	patient	NNS
cord-005603-kjcbbgse	36	28	.	.	.
cord-005603-kjcbbgse	37	1	The	the	DT
cord-005603-kjcbbgse	37	2	prognosis	prognosis	NN
cord-005603-kjcbbgse	37	3	of	of	IN
cord-005603-kjcbbgse	37	4	septic	septic	JJ
cord-005603-kjcbbgse	37	5	syndromes	syndrome	NNS
cord-005603-kjcbbgse	37	6	is	be	VBZ
cord-005603-kjcbbgse	37	7	related	relate	VBN
cord-005603-kjcbbgse	37	8	to	to	IN
cord-005603-kjcbbgse	37	9	underlying	underlie	VBG
cord-005603-kjcbbgse	37	10	diseases	disease	NNS
cord-005603-kjcbbgse	37	11	and	and	CC
cord-005603-kjcbbgse	37	12	the	the	DT
cord-005603-kjcbbgse	37	13	severity	severity	NN
cord-005603-kjcbbgse	37	14	of	of	IN
cord-005603-kjcbbgse	37	15	the	the	DT
cord-005603-kjcbbgse	37	16	inflammatory	inflammatory	JJ
cord-005603-kjcbbgse	37	17	response	response	NN
cord-005603-kjcbbgse	37	18	and	and	CC
cord-005603-kjcbbgse	37	19	its	-PRON-	PRP$
cord-005603-kjcbbgse	37	20	sequelae	sequela	NNS
cord-005603-kjcbbgse	37	21	,	,	,
cord-005603-kjcbbgse	37	22	reflected	reflect	VBN
cord-005603-kjcbbgse	37	23	in	in	IN
cord-005603-kjcbbgse	37	24	shock	shock	NN
cord-005603-kjcbbgse	37	25	and	and	CC
cord-005603-kjcbbgse	37	26	organ	organ	NN
cord-005603-kjcbbgse	37	27	dysfunction	dysfunction	NN
cord-005603-kjcbbgse	37	28	/	/	SYM
cord-005603-kjcbbgse	37	29	failures	failure	NNS
cord-005603-kjcbbgse	37	30	.	.	.
cord-005603-kjcbbgse	38	1	Similarly	similarly	RB
cord-005603-kjcbbgse	38	2	to	to	IN
cord-005603-kjcbbgse	38	3	ARDS	ARDS	NNP
cord-005603-kjcbbgse	38	4	[	[	-LRB-
cord-005603-kjcbbgse	38	5	1	1	CD
cord-005603-kjcbbgse	38	6	]	]	-RRB-
cord-005603-kjcbbgse	38	7	the	the	DT
cord-005603-kjcbbgse	38	8	definition	definition	NN
cord-005603-kjcbbgse	38	9	of	of	IN
cord-005603-kjcbbgse	38	10	septic	septic	JJ
cord-005603-kjcbbgse	38	11	syndromes	syndrome	NNS
cord-005603-kjcbbgse	38	12	has	have	VBZ
cord-005603-kjcbbgse	38	13	caused	cause	VBN
cord-005603-kjcbbgse	38	14	much	much	JJ
cord-005603-kjcbbgse	38	15	controversy	controversy	NN
cord-005603-kjcbbgse	38	16	and	and	CC
cord-005603-kjcbbgse	38	17	debate	debate	NN
cord-005603-kjcbbgse	38	18	in	in	IN
cord-005603-kjcbbgse	38	19	the	the	DT
cord-005603-kjcbbgse	38	20	past	past	JJ
cord-005603-kjcbbgse	38	21	decade	decade	NN
cord-005603-kjcbbgse	38	22	.	.	.
cord-005603-kjcbbgse	39	1	Many	many	JJ
cord-005603-kjcbbgse	39	2	of	of	IN
cord-005603-kjcbbgse	39	3	these	these	DT
cord-005603-kjcbbgse	39	4	controversies	controversy	NNS
cord-005603-kjcbbgse	39	5	have	have	VBP
cord-005603-kjcbbgse	39	6	stemmed	stem	VBN
cord-005603-kjcbbgse	39	7	from	from	IN
cord-005603-kjcbbgse	39	8	the	the	DT
cord-005603-kjcbbgse	39	9	frustration	frustration	NN
cord-005603-kjcbbgse	39	10	accumulated	accumulate	VBN
cord-005603-kjcbbgse	39	11	following	follow	VBG
cord-005603-kjcbbgse	39	12	the	the	DT
cord-005603-kjcbbgse	39	13	repeatedly	repeatedly	RB
cord-005603-kjcbbgse	39	14	negative	negative	JJ
cord-005603-kjcbbgse	39	15	results	result	NNS
cord-005603-kjcbbgse	39	16	of	of	IN
cord-005603-kjcbbgse	39	17	new	new	JJ
cord-005603-kjcbbgse	39	18	therapeutic	therapeutic	JJ
cord-005603-kjcbbgse	39	19	interventions	intervention	NNS
cord-005603-kjcbbgse	39	20	aiming	aim	VBG
cord-005603-kjcbbgse	39	21	at	at	IN
cord-005603-kjcbbgse	39	22	controlling	control	VBG
cord-005603-kjcbbgse	39	23	the	the	DT
cord-005603-kjcbbgse	39	24	inflammatory	inflammatory	JJ
cord-005603-kjcbbgse	39	25	response	response	NN
cord-005603-kjcbbgse	39	26	associated	associate	VBN
cord-005603-kjcbbgse	39	27	with	with	IN
cord-005603-kjcbbgse	39	28	infection	infection	NN
cord-005603-kjcbbgse	39	29	.	.	.
cord-005603-kjcbbgse	40	1	Hence	hence	RB
cord-005603-kjcbbgse	40	2	the	the	DT
cord-005603-kjcbbgse	40	3	suggestions	suggestion	NNS
cord-005603-kjcbbgse	40	4	that	that	IN
cord-005603-kjcbbgse	40	5	new	new	JJ
cord-005603-kjcbbgse	40	6	definitions	definition	NNS
cord-005603-kjcbbgse	40	7	were	be	VBD
cord-005603-kjcbbgse	40	8	needed	need	VBN
cord-005603-kjcbbgse	40	9	,	,	,
cord-005603-kjcbbgse	40	10	that	that	DT
cord-005603-kjcbbgse	40	11	would	would	MD
cord-005603-kjcbbgse	40	12	allow	allow	VB
cord-005603-kjcbbgse	40	13	a	a	DT
cord-005603-kjcbbgse	40	14	quicker	quick	JJR
cord-005603-kjcbbgse	40	15	and	and	CC
cord-005603-kjcbbgse	40	16	simpler	simple	JJR
cord-005603-kjcbbgse	40	17	identification	identification	NN
cord-005603-kjcbbgse	40	18	of	of	IN
cord-005603-kjcbbgse	40	19	septic	septic	JJ
cord-005603-kjcbbgse	40	20	patients	patient	NNS
cord-005603-kjcbbgse	40	21	for	for	IN
cord-005603-kjcbbgse	40	22	accrual	accrual	NN
cord-005603-kjcbbgse	40	23	into	into	IN
cord-005603-kjcbbgse	40	24	randomised	randomised	JJ
cord-005603-kjcbbgse	40	25	trials	trial	NNS
cord-005603-kjcbbgse	40	26	of	of	IN
cord-005603-kjcbbgse	40	27	new	new	JJ
cord-005603-kjcbbgse	40	28	therapies	therapy	NNS
cord-005603-kjcbbgse	40	29	[	[	-LRB-
cord-005603-kjcbbgse	40	30	2	2	CD
cord-005603-kjcbbgse	40	31	]	]	-RRB-
cord-005603-kjcbbgse	40	32	and	and	CC
cord-005603-kjcbbgse	40	33	that	that	DT
cord-005603-kjcbbgse	40	34	would	would	MD
cord-005603-kjcbbgse	40	35	help	help	VB
cord-005603-kjcbbgse	40	36	derive	derive	VB
cord-005603-kjcbbgse	40	37	more	more	RBR
cord-005603-kjcbbgse	40	38	consistent	consistent	JJ
cord-005603-kjcbbgse	40	39	and	and	CC
cord-005603-kjcbbgse	40	40	comparable	comparable	JJ
cord-005603-kjcbbgse	40	41	results	result	NNS
cord-005603-kjcbbgse	40	42	from	from	IN
cord-005603-kjcbbgse	40	43	epidemiological	epidemiological	JJ
cord-005603-kjcbbgse	40	44	studies	study	NNS
cord-005603-kjcbbgse	40	45	and	and	CC
cord-005603-kjcbbgse	40	46	clinical	clinical	JJ
cord-005603-kjcbbgse	40	47	trials	trial	NNS
cord-005603-kjcbbgse	40	48	.	.	.
cord-005603-kjcbbgse	41	1	While	while	IN
cord-005603-kjcbbgse	41	2	the	the	DT
cord-005603-kjcbbgse	41	3	ultimate	ultimate	JJ
cord-005603-kjcbbgse	41	4	goal	goal	NN
cord-005603-kjcbbgse	41	5	of	of	IN
cord-005603-kjcbbgse	41	6	showing	show	VBG
cord-005603-kjcbbgse	41	7	the	the	DT
cord-005603-kjcbbgse	41	8	efficacy	efficacy	NN
cord-005603-kjcbbgse	41	9	of	of	IN
cord-005603-kjcbbgse	41	10	these	these	DT
cord-005603-kjcbbgse	41	11	pharmacological	pharmacological	JJ
cord-005603-kjcbbgse	41	12	interventions	intervention	NNS
cord-005603-kjcbbgse	41	13	remains	remain	VBZ
cord-005603-kjcbbgse	41	14	elusive	elusive	JJ
cord-005603-kjcbbgse	41	15	,	,	,
cord-005603-kjcbbgse	41	16	the	the	DT
cord-005603-kjcbbgse	41	17	definitions	definition	NNS
cord-005603-kjcbbgse	41	18	elaborated	elaborate	VBN
cord-005603-kjcbbgse	41	19	then	then	RB
cord-005603-kjcbbgse	41	20	and	and	CC
cord-005603-kjcbbgse	41	21	now	now	RB
cord-005603-kjcbbgse	41	22	in	in	IN
cord-005603-kjcbbgse	41	23	widespread	widespread	JJ
cord-005603-kjcbbgse	41	24	use	use	NN
cord-005603-kjcbbgse	41	25	did	do	VBD
cord-005603-kjcbbgse	41	26	provide	provide	VB
cord-005603-kjcbbgse	41	27	the	the	DT
cord-005603-kjcbbgse	41	28	impetus	impetus	NN
cord-005603-kjcbbgse	41	29	for	for	IN
cord-005603-kjcbbgse	41	30	conducting	conduct	VBG
cord-005603-kjcbbgse	41	31	several	several	JJ
cord-005603-kjcbbgse	41	32	epidemiological	epidemiological	JJ
cord-005603-kjcbbgse	41	33	studies	study	NNS
cord-005603-kjcbbgse	41	34	aimed	aim	VBN
cord-005603-kjcbbgse	41	35	at	at	IN
cord-005603-kjcbbgse	41	36	better	well	RBR
cord-005603-kjcbbgse	41	37	characterising	characterise	VBG
cord-005603-kjcbbgse	41	38	the	the	DT
cord-005603-kjcbbgse	41	39	septic	septic	JJ
cord-005603-kjcbbgse	41	40	syndromes	syndrome	NNS
cord-005603-kjcbbgse	41	41	and	and	CC
cord-005603-kjcbbgse	41	42	their	-PRON-	PRP$
cord-005603-kjcbbgse	41	43	sequelae	sequela	NNS
cord-005603-kjcbbgse	41	44	.	.	.
cord-005603-kjcbbgse	42	1	In	in	IN
cord-005603-kjcbbgse	42	2	this	this	DT
cord-005603-kjcbbgse	42	3	paper	paper	NN
cord-005603-kjcbbgse	42	4	,	,	,
cord-005603-kjcbbgse	42	5	we	-PRON-	PRP
cord-005603-kjcbbgse	42	6	shall	shall	MD
cord-005603-kjcbbgse	42	7	review	review	VB
cord-005603-kjcbbgse	42	8	these	these	DT
cord-005603-kjcbbgse	42	9	studies	study	NNS
cord-005603-kjcbbgse	42	10	and	and	CC
cord-005603-kjcbbgse	42	11	summarise	summarise	VB
cord-005603-kjcbbgse	42	12	the	the	DT
cord-005603-kjcbbgse	42	13	current	current	JJ
cord-005603-kjcbbgse	42	14	understanding	understanding	NN
cord-005603-kjcbbgse	42	15	of	of	IN
cord-005603-kjcbbgse	42	16	the	the	DT
cord-005603-kjcbbgse	42	17	clinical	clinical	JJ
cord-005603-kjcbbgse	42	18	and	and	CC
cord-005603-kjcbbgse	42	19	microbiological	microbiological	JJ
cord-005603-kjcbbgse	42	20	epidemiology	epidemiology	NN
cord-005603-kjcbbgse	42	21	of	of	IN
cord-005603-kjcbbgse	42	22	the	the	DT
cord-005603-kjcbbgse	42	23	septic	septic	JJ
cord-005603-kjcbbgse	42	24	syndromes	syndrome	NNS
cord-005603-kjcbbgse	42	25	,	,	,
cord-005603-kjcbbgse	42	26	their	-PRON-	PRP$
cord-005603-kjcbbgse	42	27	interplay	interplay	NN
cord-005603-kjcbbgse	42	28	,	,	,
cord-005603-kjcbbgse	42	29	and	and	CC
cord-005603-kjcbbgse	42	30	outcomes	outcome	NNS
cord-005603-kjcbbgse	42	31	of	of	IN
cord-005603-kjcbbgse	42	32	patients	patient	NNS
cord-005603-kjcbbgse	42	33	affected	affect	VBN
cord-005603-kjcbbgse	42	34	.	.	.
cord-005603-kjcbbgse	43	1	Finally	finally	RB
cord-005603-kjcbbgse	43	2	,	,	,
cord-005603-kjcbbgse	43	3	we	-PRON-	PRP
cord-005603-kjcbbgse	43	4	shall	shall	MD
cord-005603-kjcbbgse	43	5	discuss	discuss	VB
cord-005603-kjcbbgse	43	6	the	the	DT
cord-005603-kjcbbgse	43	7	implications	implication	NNS
cord-005603-kjcbbgse	43	8	of	of	IN
cord-005603-kjcbbgse	43	9	this	this	DT
cord-005603-kjcbbgse	43	10	information	information	NN
cord-005603-kjcbbgse	43	11	for	for	IN
cord-005603-kjcbbgse	43	12	conducting	conduct	VBG
cord-005603-kjcbbgse	43	13	clinical	clinical	JJ
cord-005603-kjcbbgse	43	14	trials	trial	NNS
cord-005603-kjcbbgse	43	15	.	.	.
cord-005603-kjcbbgse	44	1	The	the	DT
cord-005603-kjcbbgse	44	2	term	term	NN
cord-005603-kjcbbgse	44	3	ªsepsisº	ªsepsisº	NN
cord-005603-kjcbbgse	44	4	has	have	VBZ
cord-005603-kjcbbgse	44	5	long	long	RB
cord-005603-kjcbbgse	44	6	been	be	VBN
cord-005603-kjcbbgse	44	7	used	use	VBN
cord-005603-kjcbbgse	44	8	interchangeably	interchangeably	RB
cord-005603-kjcbbgse	44	9	with	with	IN
cord-005603-kjcbbgse	44	10	bacteraemia	bacteraemia	NN
cord-005603-kjcbbgse	44	11	,	,	,
cord-005603-kjcbbgse	44	12	severe	severe	JJ
cord-005603-kjcbbgse	44	13	sepsis	sepsis	NN
cord-005603-kjcbbgse	44	14	or	or	CC
cord-005603-kjcbbgse	44	15	even	even	RB
cord-005603-kjcbbgse	44	16	septic	septic	JJ
cord-005603-kjcbbgse	44	17	shock	shock	NN
cord-005603-kjcbbgse	44	18	,	,	,
cord-005603-kjcbbgse	44	19	undoubtedly	undoubtedly	RB
cord-005603-kjcbbgse	44	20	a	a	DT
cord-005603-kjcbbgse	44	21	source	source	NN
cord-005603-kjcbbgse	44	22	of	of	IN
cord-005603-kjcbbgse	44	23	some	some	DT
cord-005603-kjcbbgse	44	24	confusion	confusion	NN
cord-005603-kjcbbgse	44	25	and	and	CC
cord-005603-kjcbbgse	44	26	difficulty	difficulty	NN
cord-005603-kjcbbgse	44	27	in	in	IN
cord-005603-kjcbbgse	44	28	putting	put	VBG
cord-005603-kjcbbgse	44	29	together	together	RP
cord-005603-kjcbbgse	44	30	results	result	NNS
cord-005603-kjcbbgse	44	31	from	from	IN
cord-005603-kjcbbgse	44	32	published	publish	VBN
cord-005603-kjcbbgse	44	33	studies	study	NNS
cord-005603-kjcbbgse	44	34	.	.	.
cord-005603-kjcbbgse	45	1	In	in	IN
cord-005603-kjcbbgse	45	2	1992	1992	CD
cord-005603-kjcbbgse	45	3	the	the	DT
cord-005603-kjcbbgse	45	4	US	US	NNP
cord-005603-kjcbbgse	45	5	expert	expert	NN
cord-005603-kjcbbgse	45	6	panel	panel	NN
cord-005603-kjcbbgse	45	7	from	from	IN
cord-005603-kjcbbgse	45	8	the	the	DT
cord-005603-kjcbbgse	45	9	American	American	NNP
cord-005603-kjcbbgse	45	10	College	College	NNP
cord-005603-kjcbbgse	45	11	of	of	IN
cord-005603-kjcbbgse	45	12	Chest	Chest	NNP
cord-005603-kjcbbgse	45	13	Physicians	Physicians	NNPS
cord-005603-kjcbbgse	45	14	and	and	CC
cord-005603-kjcbbgse	45	15	the	the	DT
cord-005603-kjcbbgse	45	16	Society	Society	NNP
cord-005603-kjcbbgse	45	17	of	of	IN
cord-005603-kjcbbgse	45	18	Critical	Critical	NNP
cord-005603-kjcbbgse	45	19	Care	Care	NNP
cord-005603-kjcbbgse	45	20	Medicine	Medicine	NNP
cord-005603-kjcbbgse	45	21	[	[	-LRB-
cord-005603-kjcbbgse	45	22	2	2	CD
cord-005603-kjcbbgse	45	23	]	]	-RRB-
cord-005603-kjcbbgse	45	24	produced	produce	VBD
cord-005603-kjcbbgse	45	25	a	a	DT
cord-005603-kjcbbgse	45	26	consensus	consensus	NN
cord-005603-kjcbbgse	45	27	statement	statement	NN
cord-005603-kjcbbgse	45	28	on	on	IN
cord-005603-kjcbbgse	45	29	the	the	DT
cord-005603-kjcbbgse	45	30	suggested	suggest	VBN
cord-005603-kjcbbgse	45	31	definitions	definition	NNS
cord-005603-kjcbbgse	45	32	to	to	TO
cord-005603-kjcbbgse	45	33	characterise	characterise	VB
cord-005603-kjcbbgse	45	34	the	the	DT
cord-005603-kjcbbgse	45	35	various	various	JJ
cord-005603-kjcbbgse	45	36	stages	stage	NNS
cord-005603-kjcbbgse	45	37	of	of	IN
cord-005603-kjcbbgse	45	38	the	the	DT
cord-005603-kjcbbgse	45	39	associated	associate	VBN
cord-005603-kjcbbgse	45	40	inflammatory	inflammatory	JJ
cord-005603-kjcbbgse	45	41	response	response	NN
cord-005603-kjcbbgse	45	42	and	and	CC
cord-005603-kjcbbgse	45	43	help	help	NN
cord-005603-kjcbbgse	45	44	in	in	IN
cord-005603-kjcbbgse	45	45	differentiating	differentiate	VBG
cord-005603-kjcbbgse	45	46	infectious	infectious	JJ
cord-005603-kjcbbgse	45	47	from	from	IN
cord-005603-kjcbbgse	45	48	non	non	JJ
cord-005603-kjcbbgse	45	49	-	-	JJ
cord-005603-kjcbbgse	45	50	infectious	infectious	JJ
cord-005603-kjcbbgse	45	51	processes	process	NNS
cord-005603-kjcbbgse	45	52	.	.	.
cord-005603-kjcbbgse	46	1	While	while	IN
cord-005603-kjcbbgse	46	2	the	the	DT
cord-005603-kjcbbgse	46	3	recent	recent	JJ
cord-005603-kjcbbgse	46	4	definitions	definition	NNS
cord-005603-kjcbbgse	46	5	are	be	VBP
cord-005603-kjcbbgse	46	6	centred	centre	VBN
cord-005603-kjcbbgse	46	7	on	on	IN
cord-005603-kjcbbgse	46	8	the	the	DT
cord-005603-kjcbbgse	46	9	documentation	documentation	NN
cord-005603-kjcbbgse	46	10	of	of	IN
cord-005603-kjcbbgse	46	11	infection	infection	NN
cord-005603-kjcbbgse	46	12	,	,	,
cord-005603-kjcbbgse	46	13	they	-PRON-	PRP
cord-005603-kjcbbgse	46	14	aim	aim	VBP
cord-005603-kjcbbgse	46	15	at	at	IN
cord-005603-kjcbbgse	46	16	encompassing	encompass	VBG
cord-005603-kjcbbgse	46	17	all	all	DT
cord-005603-kjcbbgse	46	18	potential	potential	JJ
cord-005603-kjcbbgse	46	19	clinical	clinical	JJ
cord-005603-kjcbbgse	46	20	presentations	presentation	NNS
cord-005603-kjcbbgse	46	21	of	of	IN
cord-005603-kjcbbgse	46	22	infection	infection	NN
cord-005603-kjcbbgse	46	23	and	and	CC
cord-005603-kjcbbgse	46	24	its	-PRON-	PRP$
cord-005603-kjcbbgse	46	25	consequences	consequence	NNS
cord-005603-kjcbbgse	46	26	.	.	.
cord-005603-kjcbbgse	47	1	The	the	DT
cord-005603-kjcbbgse	47	2	principles	principle	NNS
cord-005603-kjcbbgse	47	3	followed	follow	VBD
cord-005603-kjcbbgse	47	4	in	in	IN
cord-005603-kjcbbgse	47	5	elaborating	elaborate	VBG
cord-005603-kjcbbgse	47	6	the	the	DT
cord-005603-kjcbbgse	47	7	definitions	definition	NNS
cord-005603-kjcbbgse	47	8	were	be	VBD
cord-005603-kjcbbgse	47	9	that	that	DT
cord-005603-kjcbbgse	47	10	:	:	:
cord-005603-kjcbbgse	47	11	(	(	-LRB-
cord-005603-kjcbbgse	47	12	1	1	LS
cord-005603-kjcbbgse	47	13	)	)	-RRB-
cord-005603-kjcbbgse	47	14	infectious	infectious	JJ
cord-005603-kjcbbgse	47	15	(	(	-LRB-
cord-005603-kjcbbgse	47	16	and	and	CC
cord-005603-kjcbbgse	47	17	some	some	DT
cord-005603-kjcbbgse	47	18	non	non	JJ
cord-005603-kjcbbgse	47	19	-	-	JJ
cord-005603-kjcbbgse	47	20	infectious	infectious	JJ
cord-005603-kjcbbgse	47	21	)	)	-RRB-
cord-005603-kjcbbgse	47	22	processes	process	NNS
cord-005603-kjcbbgse	47	23	,	,	,
cord-005603-kjcbbgse	47	24	whatever	whatever	WDT
cord-005603-kjcbbgse	47	25	their	-PRON-	PRP$
cord-005603-kjcbbgse	47	26	cause	cause	NN
cord-005603-kjcbbgse	47	27	,	,	,
cord-005603-kjcbbgse	47	28	elicit	elicit	VB
cord-005603-kjcbbgse	47	29	a	a	DT
cord-005603-kjcbbgse	47	30	common	common	JJ
cord-005603-kjcbbgse	47	31	systemic	systemic	JJ
cord-005603-kjcbbgse	47	32	response	response	NN
cord-005603-kjcbbgse	47	33	which	which	WDT
cord-005603-kjcbbgse	47	34	,	,	,
cord-005603-kjcbbgse	47	35	although	although	IN
cord-005603-kjcbbgse	47	36	of	of	IN
cord-005603-kjcbbgse	47	37	variable	variable	JJ
cord-005603-kjcbbgse	47	38	intensity	intensity	NN
cord-005603-kjcbbgse	47	39	,	,	,
cord-005603-kjcbbgse	47	40	is	be	VBZ
cord-005603-kjcbbgse	47	41	the	the	DT
cord-005603-kjcbbgse	47	42	expression	expression	NN
cord-005603-kjcbbgse	47	43	of	of	IN
cord-005603-kjcbbgse	47	44	common	common	JJ
cord-005603-kjcbbgse	47	45	pathophysiologic	pathophysiologic	JJ
cord-005603-kjcbbgse	47	46	pathways	pathway	NNS
cord-005603-kjcbbgse	47	47	resulting	result	VBG
cord-005603-kjcbbgse	47	48	from	from	IN
cord-005603-kjcbbgse	47	49	the	the	DT
cord-005603-kjcbbgse	47	50	expression	expression	NN
cord-005603-kjcbbgse	47	51	and	and	CC
cord-005603-kjcbbgse	47	52	interaction	interaction	NN
cord-005603-kjcbbgse	47	53	of	of	IN
cord-005603-kjcbbgse	47	54	various	various	JJ
cord-005603-kjcbbgse	47	55	humoral	humoral	JJ
cord-005603-kjcbbgse	47	56	and	and	CC
cord-005603-kjcbbgse	47	57	cellular	cellular	JJ
cord-005603-kjcbbgse	47	58	mediators	mediator	NNS
cord-005603-kjcbbgse	47	59	and	and	CC
cord-005603-kjcbbgse	47	60	cytokines	cytokine	NNS
cord-005603-kjcbbgse	47	61	;	;	,
cord-005603-kjcbbgse	47	62	(	(	-LRB-
cord-005603-kjcbbgse	47	63	2	2	LS
cord-005603-kjcbbgse	47	64	)	)	-RRB-
cord-005603-kjcbbgse	47	65	sepsis	sepsis	NN
cord-005603-kjcbbgse	47	66	and	and	CC
cord-005603-kjcbbgse	47	67	related	related	JJ
cord-005603-kjcbbgse	47	68	terms	term	NNS
cord-005603-kjcbbgse	47	69	should	should	MD
cord-005603-kjcbbgse	47	70	be	be	VB
cord-005603-kjcbbgse	47	71	reserved	reserve	VBN
cord-005603-kjcbbgse	47	72	for	for	IN
cord-005603-kjcbbgse	47	73	infectious	infectious	JJ
cord-005603-kjcbbgse	47	74	processes	process	NNS
cord-005603-kjcbbgse	47	75	;	;	:
cord-005603-kjcbbgse	47	76	and	and	CC
cord-005603-kjcbbgse	47	77	(	(	-LRB-
cord-005603-kjcbbgse	47	78	3	3	LS
cord-005603-kjcbbgse	47	79	)	)	-RRB-
cord-005603-kjcbbgse	47	80	there	there	EX
cord-005603-kjcbbgse	47	81	is	be	VBZ
cord-005603-kjcbbgse	47	82	a	a	DT
cord-005603-kjcbbgse	47	83	continuum	continuum	NN
cord-005603-kjcbbgse	47	84	between	between	IN
cord-005603-kjcbbgse	47	85	the	the	DT
cord-005603-kjcbbgse	47	86	various	various	JJ
cord-005603-kjcbbgse	47	87	stages	stage	NNS
cord-005603-kjcbbgse	47	88	of	of	IN
cord-005603-kjcbbgse	47	89	this	this	DT
cord-005603-kjcbbgse	47	90	response	response	NN
cord-005603-kjcbbgse	47	91	to	to	IN
cord-005603-kjcbbgse	47	92	infection	infection	NN
cord-005603-kjcbbgse	47	93	(	(	-LRB-
cord-005603-kjcbbgse	47	94	Table	table	NN
cord-005603-kjcbbgse	47	95	1	1	CD
cord-005603-kjcbbgse	47	96	)	)	-RRB-
cord-005603-kjcbbgse	47	97	.	.	.
cord-005603-kjcbbgse	48	1	Although	although	IN
cord-005603-kjcbbgse	48	2	the	the	DT
cord-005603-kjcbbgse	48	3	definitions	definition	NNS
cord-005603-kjcbbgse	48	4	do	do	VBP
cord-005603-kjcbbgse	48	5	provide	provide	VB
cord-005603-kjcbbgse	48	6	a	a	DT
cord-005603-kjcbbgse	48	7	framework	framework	NN
cord-005603-kjcbbgse	48	8	for	for	IN
cord-005603-kjcbbgse	48	9	classifying	classify	VBG
cord-005603-kjcbbgse	48	10	patients	patient	NNS
cord-005603-kjcbbgse	48	11	±	±	NNP
cord-005603-kjcbbgse	48	12	a	a	DT
cord-005603-kjcbbgse	48	13	useful	useful	JJ
cord-005603-kjcbbgse	48	14	achievement	achievement	NN
cord-005603-kjcbbgse	48	15	for	for	IN
cord-005603-kjcbbgse	48	16	enrolling	enrol	VBG
cord-005603-kjcbbgse	48	17	patients	patient	NNS
cord-005603-kjcbbgse	48	18	into	into	IN
cord-005603-kjcbbgse	48	19	clinical	clinical	JJ
cord-005603-kjcbbgse	48	20	trials	trial	NNS
cord-005603-kjcbbgse	48	21	±	±	XX
cord-005603-kjcbbgse	49	1	a	a	DT
cord-005603-kjcbbgse	49	2	persisting	persist	VBG
cord-005603-kjcbbgse	49	3	and	and	CC
cord-005603-kjcbbgse	49	4	unresolved	unresolved	JJ
cord-005603-kjcbbgse	49	5	problem	problem	NN
cord-005603-kjcbbgse	49	6	facing	face	VBG
cord-005603-kjcbbgse	49	7	clinicians	clinician	NNS
cord-005603-kjcbbgse	49	8	in	in	IN
cord-005603-kjcbbgse	49	9	clinical	clinical	JJ
cord-005603-kjcbbgse	49	10	practice	practice	NN
cord-005603-kjcbbgse	49	11	is	be	VBZ
cord-005603-kjcbbgse	49	12	that	that	IN
cord-005603-kjcbbgse	49	13	the	the	DT
cord-005603-kjcbbgse	49	14	definitions	definition	NNS
cord-005603-kjcbbgse	49	15	are	be	VBP
cord-005603-kjcbbgse	49	16	in	in	IN
cord-005603-kjcbbgse	49	17	part	part	NN
cord-005603-kjcbbgse	49	18	retrospective	retrospective	NN
cord-005603-kjcbbgse	49	19	(	(	-LRB-
cord-005603-kjcbbgse	49	20	based	base	VBN
cord-005603-kjcbbgse	49	21	on	on	IN
cord-005603-kjcbbgse	49	22	the	the	DT
cord-005603-kjcbbgse	49	23	documentation	documentation	NN
cord-005603-kjcbbgse	49	24	of	of	IN
cord-005603-kjcbbgse	49	25	infection	infection	NN
cord-005603-kjcbbgse	49	26	)	)	-RRB-
cord-005603-kjcbbgse	49	27	and	and	CC
cord-005603-kjcbbgse	49	28	do	do	VBP
cord-005603-kjcbbgse	49	29	not	not	RB
cord-005603-kjcbbgse	49	30	actually	actually	RB
cord-005603-kjcbbgse	49	31	help	help	VB
cord-005603-kjcbbgse	49	32	them	-PRON-	PRP
cord-005603-kjcbbgse	49	33	solve	solve	VB
cord-005603-kjcbbgse	49	34	the	the	DT
cord-005603-kjcbbgse	49	35	major	major	JJ
cord-005603-kjcbbgse	49	36	clinical	clinical	JJ
cord-005603-kjcbbgse	49	37	issue	issue	NN
cord-005603-kjcbbgse	49	38	when	when	WRB
cord-005603-kjcbbgse	49	39	faced	face	VBN
cord-005603-kjcbbgse	49	40	with	with	IN
cord-005603-kjcbbgse	49	41	a	a	DT
cord-005603-kjcbbgse	49	42	septic	septic	JJ
cord-005603-kjcbbgse	49	43	patient	patient	NN
cord-005603-kjcbbgse	49	44	,	,	,
cord-005603-kjcbbgse	49	45	which	which	WDT
cord-005603-kjcbbgse	49	46	is	be	VBZ
cord-005603-kjcbbgse	49	47	to	to	TO
cord-005603-kjcbbgse	49	48	differentiate	differentiate	VB
cord-005603-kjcbbgse	49	49	infectious	infectious	JJ
cord-005603-kjcbbgse	49	50	from	from	IN
cord-005603-kjcbbgse	49	51	non	non	JJ
cord-005603-kjcbbgse	49	52	-	-	JJ
cord-005603-kjcbbgse	49	53	infectious	infectious	JJ
cord-005603-kjcbbgse	49	54	processes	process	NNS
cord-005603-kjcbbgse	49	55	.	.	.
cord-005603-kjcbbgse	50	1	Another	another	DT
cord-005603-kjcbbgse	50	2	critique	critique	NN
cord-005603-kjcbbgse	50	3	of	of	IN
cord-005603-kjcbbgse	50	4	this	this	DT
cord-005603-kjcbbgse	50	5	classification	classification	NN
cord-005603-kjcbbgse	50	6	has	have	VBZ
cord-005603-kjcbbgse	50	7	been	be	VBN
cord-005603-kjcbbgse	50	8	that	that	IN
cord-005603-kjcbbgse	50	9	its	-PRON-	PRP$
cord-005603-kjcbbgse	50	10	broad	broad	RB
cord-005603-kjcbbgse	50	11	-	-	HYPH
cord-005603-kjcbbgse	50	12	based	base	VBN
cord-005603-kjcbbgse	50	13	approach	approach	NN
cord-005603-kjcbbgse	50	14	,	,	,
cord-005603-kjcbbgse	50	15	intended	intend	VBN
cord-005603-kjcbbgse	50	16	to	to	TO
cord-005603-kjcbbgse	50	17	identify	identify	VB
cord-005603-kjcbbgse	50	18	patients	patient	NNS
cord-005603-kjcbbgse	50	19	early	early	RB
cord-005603-kjcbbgse	50	20	in	in	IN
cord-005603-kjcbbgse	50	21	the	the	DT
cord-005603-kjcbbgse	50	22	course	course	NN
cord-005603-kjcbbgse	50	23	of	of	IN
cord-005603-kjcbbgse	50	24	the	the	DT
cord-005603-kjcbbgse	50	25	infectious	infectious	JJ
cord-005603-kjcbbgse	50	26	process	process	NN
cord-005603-kjcbbgse	50	27	,	,	,
cord-005603-kjcbbgse	50	28	did	do	VBD
cord-005603-kjcbbgse	50	29	not	not	RB
cord-005603-kjcbbgse	50	30	in	in	IN
cord-005603-kjcbbgse	50	31	fact	fact	NN
cord-005603-kjcbbgse	50	32	help	help	VB
cord-005603-kjcbbgse	50	33	physicians	physician	NNS
cord-005603-kjcbbgse	50	34	,	,	,
cord-005603-kjcbbgse	50	35	and	and	CC
cord-005603-kjcbbgse	50	36	especially	especially	RB
cord-005603-kjcbbgse	50	37	intensivists	intensivists	NNP
cord-005603-kjcbbgse	50	38	,	,	,
cord-005603-kjcbbgse	50	39	to	to	TO
cord-005603-kjcbbgse	50	40	better	better	RB
cord-005603-kjcbbgse	50	41	characterise	characterise	VB
cord-005603-kjcbbgse	50	42	patients	patient	NNS
cord-005603-kjcbbgse	50	43	exhibiting	exhibit	VBG
cord-005603-kjcbbgse	50	44	the	the	DT
cord-005603-kjcbbgse	50	45	least	least	JJS
cord-005603-kjcbbgse	50	46	severe	severe	JJ
cord-005603-kjcbbgse	50	47	presentations	presentation	NNS
cord-005603-kjcbbgse	50	48	of	of	IN
cord-005603-kjcbbgse	50	49	the	the	DT
cord-005603-kjcbbgse	50	50	septic	septic	JJ
cord-005603-kjcbbgse	50	51	syndromes	syndrome	NNS
cord-005603-kjcbbgse	50	52	.	.	.
cord-005603-kjcbbgse	51	1	In	in	IN
cord-005603-kjcbbgse	51	2	other	other	JJ
cord-005603-kjcbbgse	51	3	words	word	NNS
cord-005603-kjcbbgse	51	4	,	,	,
cord-005603-kjcbbgse	51	5	the	the	DT
cord-005603-kjcbbgse	51	6	high	high	JJ
cord-005603-kjcbbgse	51	7	sensitivity	sensitivity	NN
cord-005603-kjcbbgse	51	8	of	of	IN
cord-005603-kjcbbgse	51	9	the	the	DT
cord-005603-kjcbbgse	51	10	definition	definition	NN
cord-005603-kjcbbgse	51	11	is	be	VBZ
cord-005603-kjcbbgse	51	12	counterbalanced	counterbalance	VBN
cord-005603-kjcbbgse	51	13	by	by	IN
cord-005603-kjcbbgse	51	14	a	a	DT
cord-005603-kjcbbgse	51	15	rather	rather	RB
cord-005603-kjcbbgse	51	16	low	low	JJ
cord-005603-kjcbbgse	51	17	specificity	specificity	NN
cord-005603-kjcbbgse	51	18	.	.	.
cord-005603-kjcbbgse	52	1	Finally	finally	RB
cord-005603-kjcbbgse	52	2	,	,	,
cord-005603-kjcbbgse	52	3	even	even	RB
cord-005603-kjcbbgse	52	4	the	the	DT
cord-005603-kjcbbgse	52	5	sensitivity	sensitivity	NN
cord-005603-kjcbbgse	52	6	of	of	IN
cord-005603-kjcbbgse	52	7	the	the	DT
cord-005603-kjcbbgse	52	8	definitions	definition	NNS
cord-005603-kjcbbgse	52	9	has	have	VBZ
cord-005603-kjcbbgse	52	10	been	be	VBN
cord-005603-kjcbbgse	52	11	questioned	question	VBN
cord-005603-kjcbbgse	52	12	,	,	,
cord-005603-kjcbbgse	52	13	as	as	IN
cord-005603-kjcbbgse	52	14	there	there	EX
cord-005603-kjcbbgse	52	15	are	be	VBP
cord-005603-kjcbbgse	52	16	unquestionably	unquestionably	RB
cord-005603-kjcbbgse	52	17	infected	infect	VBN
cord-005603-kjcbbgse	52	18	patients	patient	NNS
cord-005603-kjcbbgse	52	19	that	that	WDT
cord-005603-kjcbbgse	52	20	do	do	VBP
cord-005603-kjcbbgse	52	21	not	not	RB
cord-005603-kjcbbgse	52	22	meet	meet	VB
cord-005603-kjcbbgse	52	23	sepsis	sepsis	NN
cord-005603-kjcbbgse	52	24	criteria	criterion	NNS
cord-005603-kjcbbgse	52	25	.	.	.
cord-005603-kjcbbgse	53	1	Nevertheless	nevertheless	RB
cord-005603-kjcbbgse	53	2	,	,	,
cord-005603-kjcbbgse	53	3	several	several	JJ
cord-005603-kjcbbgse	53	4	large	large	JJ
cord-005603-kjcbbgse	53	5	epidemiological	epidemiological	JJ
cord-005603-kjcbbgse	53	6	studies	study	NNS
cord-005603-kjcbbgse	53	7	conducted	conduct	VBN
cord-005603-kjcbbgse	53	8	after	after	IN
cord-005603-kjcbbgse	53	9	this	this	DT
cord-005603-kjcbbgse	53	10	conference	conference	NN
cord-005603-kjcbbgse	53	11	have	have	VBP
cord-005603-kjcbbgse	53	12	contributed	contribute	VBN
cord-005603-kjcbbgse	53	13	to	to	IN
cord-005603-kjcbbgse	53	14	S	S	NNP
cord-005603-kjcbbgse	53	15	65	65	CD
cord-005603-kjcbbgse	53	16	Sepsis	sepsis	NN
cord-005603-kjcbbgse	53	17	-	-	HYPH
cord-005603-kjcbbgse	53	18	induced	induce	VBN
cord-005603-kjcbbgse	53	19	hypotension	hypotension	NN
cord-005603-kjcbbgse	53	20	,	,	,
cord-005603-kjcbbgse	53	21	persisting	persist	VBG
cord-005603-kjcbbgse	53	22	despite	despite	IN
cord-005603-kjcbbgse	53	23	adequate	adequate	JJ
cord-005603-kjcbbgse	53	24	fluid	fluid	JJ
cord-005603-kjcbbgse	53	25	resuscitation	resuscitation	NN
cord-005603-kjcbbgse	53	26	,	,	,
cord-005603-kjcbbgse	53	27	(	(	-LRB-
cord-005603-kjcbbgse	53	28	2	2	CD
cord-005603-kjcbbgse	53	29	,	,	,
cord-005603-kjcbbgse	53	30	3	3	CD
cord-005603-kjcbbgse	53	31	)	)	-RRB-
cord-005603-kjcbbgse	53	32	and	and	CC
cord-005603-kjcbbgse	53	33	manifestations	manifestation	NNS
cord-005603-kjcbbgse	53	34	of	of	IN
cord-005603-kjcbbgse	53	35	hypoperfusion	hypoperfusion	NN
cord-005603-kjcbbgse	53	36	as	as	IN
cord-005603-kjcbbgse	53	37	listed	list	VBN
cord-005603-kjcbbgse	53	38	in	in	IN
cord-005603-kjcbbgse	53	39	5	5	CD
cord-005603-kjcbbgse	53	40	7	7	CD
cord-005603-kjcbbgse	53	41	.	.	.
cord-005603-kjcbbgse	54	1	Hypotension	hypotension	NN
cord-005603-kjcbbgse	54	2	,	,	,
cord-005603-kjcbbgse	54	3	sepsis	sepsis	NN
cord-005603-kjcbbgse	54	4	-	-	HYPH
cord-005603-kjcbbgse	54	5	induced	induce	VBN
cord-005603-kjcbbgse	54	6	A	a	DT
cord-005603-kjcbbgse	54	7	decrease	decrease	NN
cord-005603-kjcbbgse	54	8	in	in	IN
cord-005603-kjcbbgse	54	9	systolic	systolic	JJ
cord-005603-kjcbbgse	54	10	blood	blood	NN
cord-005603-kjcbbgse	54	11	pressure	pressure	NN
cord-005603-kjcbbgse	54	12	to	to	IN
cord-005603-kjcbbgse	54	13	<	<	XX
cord-005603-kjcbbgse	54	14	90	90	CD
cord-005603-kjcbbgse	54	15	mm	mm	CD
cord-005603-kjcbbgse	54	16	Hg	Hg	NNP
cord-005603-kjcbbgse	54	17	,	,	,
cord-005603-kjcbbgse	54	18	or	or	CC
cord-005603-kjcbbgse	54	19	of	of	IN
cord-005603-kjcbbgse	54	20	>	>	XX
cord-005603-kjcbbgse	55	1	40	40	CD
cord-005603-kjcbbgse	55	2	mm	mm	CD
cord-005603-kjcbbgse	55	3	Hg	hg	NN
cord-005603-kjcbbgse	55	4	from	from	IN
cord-005603-kjcbbgse	55	5	baseline	baseline	NN
cord-005603-kjcbbgse	55	6	,	,	,
cord-005603-kjcbbgse	55	7	in	in	IN
cord-005603-kjcbbgse	55	8	the	the	DT
cord-005603-kjcbbgse	55	9	absence	absence	NN
cord-005603-kjcbbgse	55	10	of	of	IN
cord-005603-kjcbbgse	55	11	other	other	JJ
cord-005603-kjcbbgse	55	12	cause	cause	NN
cord-005603-kjcbbgse	55	13	for	for	IN
cord-005603-kjcbbgse	55	14	hypotension	hypotension	NN
cord-005603-kjcbbgse	55	15	(	(	-LRB-
cord-005603-kjcbbgse	55	16	3	3	LS
cord-005603-kjcbbgse	55	17	)	)	-RRB-
cord-005603-kjcbbgse	55	18	(	(	-LRB-
cord-005603-kjcbbgse	55	19	1	1	CD
cord-005603-kjcbbgse	55	20	)	)	-RRB-
cord-005603-kjcbbgse	56	1	The	the	DT
cord-005603-kjcbbgse	56	2	SIRS	SIRS	NNP
cord-005603-kjcbbgse	56	3	may	may	MD
cord-005603-kjcbbgse	56	4	be	be	VB
cord-005603-kjcbbgse	56	5	caused	cause	VBN
cord-005603-kjcbbgse	56	6	by	by	IN
cord-005603-kjcbbgse	56	7	a	a	DT
cord-005603-kjcbbgse	56	8	variety	variety	NN
cord-005603-kjcbbgse	56	9	of	of	IN
cord-005603-kjcbbgse	56	10	insults	insult	NNS
cord-005603-kjcbbgse	56	11	in	in	IN
cord-005603-kjcbbgse	56	12	addition	addition	NN
cord-005603-kjcbbgse	56	13	to	to	IN
cord-005603-kjcbbgse	56	14	infection	infection	NN
cord-005603-kjcbbgse	56	15	,	,	,
cord-005603-kjcbbgse	56	16	including	include	VBG
cord-005603-kjcbbgse	56	17	but	but	CC
cord-005603-kjcbbgse	56	18	not	not	RB
cord-005603-kjcbbgse	56	19	limited	limited	JJ
cord-005603-kjcbbgse	56	20	to	to	IN
cord-005603-kjcbbgse	56	21	trauma	trauma	NN
cord-005603-kjcbbgse	56	22	and	and	CC
cord-005603-kjcbbgse	56	23	status	status	NN
cord-005603-kjcbbgse	56	24	post	post	JJ
cord-005603-kjcbbgse	56	25	-	-	JJ
cord-005603-kjcbbgse	56	26	major	major	JJ
cord-005603-kjcbbgse	56	27	surgery	surgery	NN
cord-005603-kjcbbgse	56	28	,	,	,
cord-005603-kjcbbgse	56	29	acute	acute	JJ
cord-005603-kjcbbgse	56	30	pancreatitis	pancreatitis	NN
cord-005603-kjcbbgse	56	31	,	,	,
cord-005603-kjcbbgse	56	32	and	and	CC
cord-005603-kjcbbgse	56	33	burns	burn	NNS
cord-005603-kjcbbgse	56	34	(	(	-LRB-
cord-005603-kjcbbgse	56	35	2	2	CD
cord-005603-kjcbbgse	56	36	)	)	-RRB-
cord-005603-kjcbbgse	57	1	An	an	DT
cord-005603-kjcbbgse	57	2	adequate	adequate	JJ
cord-005603-kjcbbgse	57	3	fluid	fluid	JJ
cord-005603-kjcbbgse	57	4	challenge	challenge	NN
cord-005603-kjcbbgse	57	5	is	be	VBZ
cord-005603-kjcbbgse	57	6	usually	usually	RB
cord-005603-kjcbbgse	57	7	considered	consider	VBN
cord-005603-kjcbbgse	57	8	as	as	IN
cord-005603-kjcbbgse	57	9	at	at	RB
cord-005603-kjcbbgse	57	10	least	least	JJS
cord-005603-kjcbbgse	57	11	500	500	CD
cord-005603-kjcbbgse	57	12	ml	ml	NN
cord-005603-kjcbbgse	57	13	fluid	fluid	NN
cord-005603-kjcbbgse	57	14	infused	infuse	VBN
cord-005603-kjcbbgse	57	15	rapidly	rapidly	RB
cord-005603-kjcbbgse	57	16	,	,	,
cord-005603-kjcbbgse	57	17	and	and	CC
cord-005603-kjcbbgse	57	18	persisting	persist	VBG
cord-005603-kjcbbgse	57	19	hypotension	hypotension	NN
cord-005603-kjcbbgse	57	20	as	as	IN
cord-005603-kjcbbgse	57	21	one	one	CD
cord-005603-kjcbbgse	57	22	persisting	persist	VBG
cord-005603-kjcbbgse	57	23	for	for	IN
cord-005603-kjcbbgse	57	24	>	>	NN
cord-005603-kjcbbgse	57	25	1	1	CD
cord-005603-kjcbbgse	57	26	hour	hour	NN
cord-005603-kjcbbgse	57	27	(	(	-LRB-
cord-005603-kjcbbgse	57	28	3	3	CD
cord-005603-kjcbbgse	57	29	)	)	-RRB-
cord-005603-kjcbbgse	58	1	Patients	patient	NNS
cord-005603-kjcbbgse	58	2	on	on	IN
cord-005603-kjcbbgse	58	3	inotropic	inotropic	NNP
cord-005603-kjcbbgse	58	4	/	/	SYM
cord-005603-kjcbbgse	58	5	vasoactive	vasoactive	JJ
cord-005603-kjcbbgse	58	6	agents	agent	NNS
cord-005603-kjcbbgse	58	7	may	may	MD
cord-005603-kjcbbgse	58	8	not	not	RB
cord-005603-kjcbbgse	58	9	be	be	VB
cord-005603-kjcbbgse	58	10	hypotensive	hypotensive	JJ
cord-005603-kjcbbgse	58	11	at	at	IN
cord-005603-kjcbbgse	58	12	time	time	NN
cord-005603-kjcbbgse	58	13	of	of	IN
cord-005603-kjcbbgse	58	14	evaluation	evaluation	NN
cord-005603-kjcbbgse	59	1	our	-PRON-	PRP$
cord-005603-kjcbbgse	59	2	better	well	JJR
cord-005603-kjcbbgse	59	3	understanding	understanding	NN
cord-005603-kjcbbgse	59	4	and	and	CC
cord-005603-kjcbbgse	59	5	characterisation	characterisation	NN
cord-005603-kjcbbgse	59	6	of	of	IN
cord-005603-kjcbbgse	59	7	the	the	DT
cord-005603-kjcbbgse	59	8	epidemiology	epidemiology	NN
cord-005603-kjcbbgse	59	9	and	and	CC
cord-005603-kjcbbgse	59	10	relationships	relationship	NNS
cord-005603-kjcbbgse	59	11	to	to	IN
cord-005603-kjcbbgse	59	12	infection	infection	NN
cord-005603-kjcbbgse	59	13	of	of	IN
cord-005603-kjcbbgse	59	14	the	the	DT
cord-005603-kjcbbgse	59	15	various	various	JJ
cord-005603-kjcbbgse	59	16	stages	stage	NNS
cord-005603-kjcbbgse	59	17	of	of	IN
cord-005603-kjcbbgse	59	18	the	the	DT
cord-005603-kjcbbgse	59	19	inflammatory	inflammatory	JJ
cord-005603-kjcbbgse	59	20	response	response	NN
cord-005603-kjcbbgse	59	21	,	,	,
cord-005603-kjcbbgse	59	22	and	and	CC
cord-005603-kjcbbgse	59	23	of	of	IN
cord-005603-kjcbbgse	59	24	their	-PRON-	PRP$
cord-005603-kjcbbgse	59	25	outcome	outcome	NN
cord-005603-kjcbbgse	59	26	.	.	.
cord-005603-kjcbbgse	60	1	In	in	IN
cord-005603-kjcbbgse	60	2	reviewing	review	VBG
cord-005603-kjcbbgse	60	3	these	these	DT
cord-005603-kjcbbgse	60	4	,	,	,
cord-005603-kjcbbgse	60	5	we	-PRON-	PRP
cord-005603-kjcbbgse	60	6	will	will	MD
cord-005603-kjcbbgse	60	7	use	use	VB
cord-005603-kjcbbgse	60	8	definitions	definition	NNS
cord-005603-kjcbbgse	60	9	recommended	recommend	VBN
cord-005603-kjcbbgse	60	10	by	by	IN
cord-005603-kjcbbgse	60	11	the	the	DT
cord-005603-kjcbbgse	60	12	expert	expert	JJ
cord-005603-kjcbbgse	60	13	panel	panel	NN
cord-005603-kjcbbgse	60	14	[	[	-LRB-
cord-005603-kjcbbgse	60	15	2	2	CD
cord-005603-kjcbbgse	60	16	]	]	-RRB-
cord-005603-kjcbbgse	60	17	and	and	CC
cord-005603-kjcbbgse	60	18	will	will	MD
cord-005603-kjcbbgse	60	19	use	use	VB
cord-005603-kjcbbgse	60	20	the	the	DT
cord-005603-kjcbbgse	60	21	term	term	NN
cord-005603-kjcbbgse	60	22	ªseptic	ªseptic	JJ
cord-005603-kjcbbgse	60	23	syndromesº	syndromesº	NNS
cord-005603-kjcbbgse	60	24	to	to	TO
cord-005603-kjcbbgse	60	25	refer	refer	VB
cord-005603-kjcbbgse	60	26	to	to	IN
cord-005603-kjcbbgse	60	27	all	all	DT
cord-005603-kjcbbgse	60	28	stages	stage	NNS
cord-005603-kjcbbgse	60	29	of	of	IN
cord-005603-kjcbbgse	60	30	the	the	DT
cord-005603-kjcbbgse	60	31	inflammatory	inflammatory	JJ
cord-005603-kjcbbgse	60	32	response	response	NN
cord-005603-kjcbbgse	60	33	to	to	IN
cord-005603-kjcbbgse	60	34	infection	infection	NN
cord-005603-kjcbbgse	60	35	.	.	.
cord-005603-kjcbbgse	61	1	Evaluations	evaluation	NNS
cord-005603-kjcbbgse	61	2	of	of	IN
cord-005603-kjcbbgse	61	3	the	the	DT
cord-005603-kjcbbgse	61	4	incidence	incidence	NN
cord-005603-kjcbbgse	61	5	of	of	IN
cord-005603-kjcbbgse	61	6	sepsis	sepsis	NN
cord-005603-kjcbbgse	61	7	have	have	VBP
cord-005603-kjcbbgse	61	8	initially	initially	RB
cord-005603-kjcbbgse	61	9	focused	focus	VBN
cord-005603-kjcbbgse	61	10	on	on	IN
cord-005603-kjcbbgse	61	11	the	the	DT
cord-005603-kjcbbgse	61	12	most	most	RBS
cord-005603-kjcbbgse	61	13	indisputable	indisputable	JJ
cord-005603-kjcbbgse	61	14	evidence	evidence	NN
cord-005603-kjcbbgse	61	15	for	for	IN
cord-005603-kjcbbgse	61	16	infection	infection	NN
cord-005603-kjcbbgse	61	17	,	,	,
cord-005603-kjcbbgse	61	18	i.	i.	NNP
cord-005603-kjcbbgse	61	19	e.	e.	NNP
cord-005603-kjcbbgse	61	20	,	,	,
cord-005603-kjcbbgse	61	21	bacteraemia	bacteraemia	NNP
cord-005603-kjcbbgse	61	22	.	.	.
cord-005603-kjcbbgse	62	1	The	the	DT
cord-005603-kjcbbgse	62	2	incidence	incidence	NN
cord-005603-kjcbbgse	62	3	of	of	IN
cord-005603-kjcbbgse	62	4	bacteraemia	bacteraemia	NNP
cord-005603-kjcbbgse	62	5	has	have	VBZ
cord-005603-kjcbbgse	62	6	been	be	VBN
cord-005603-kjcbbgse	62	7	increasing	increase	VBG
cord-005603-kjcbbgse	62	8	steadily	steadily	RB
cord-005603-kjcbbgse	62	9	over	over	IN
cord-005603-kjcbbgse	62	10	the	the	DT
cord-005603-kjcbbgse	62	11	years	year	NNS
cord-005603-kjcbbgse	62	12	.	.	.
cord-005603-kjcbbgse	63	1	In	in	IN
cord-005603-kjcbbgse	63	2	1990	1990	CD
cord-005603-kjcbbgse	63	3	,	,	,
cord-005603-kjcbbgse	63	4	the	the	DT
cord-005603-kjcbbgse	63	5	US	US	NNP
cord-005603-kjcbbgse	63	6	National	National	NNP
cord-005603-kjcbbgse	63	7	Center	Center	NNP
cord-005603-kjcbbgse	63	8	for	for	IN
cord-005603-kjcbbgse	63	9	Health	Health	NNP
cord-005603-kjcbbgse	63	10	Statistics	Statistics	NNPS
cord-005603-kjcbbgse	63	11	reported	report	VBD
cord-005603-kjcbbgse	63	12	that	that	IN
cord-005603-kjcbbgse	63	13	the	the	DT
cord-005603-kjcbbgse	63	14	rate	rate	NN
cord-005603-kjcbbgse	63	15	of	of	IN
cord-005603-kjcbbgse	63	16	bacteraemia	bacteraemia	NN
cord-005603-kjcbbgse	63	17	had	have	VBD
cord-005603-kjcbbgse	63	18	increased	increase	VBN
cord-005603-kjcbbgse	63	19	from	from	IN
cord-005603-kjcbbgse	63	20	0.74/1,000	0.74/1,000	CD
cord-005603-kjcbbgse	63	21	to	to	TO
cord-005603-kjcbbgse	63	22	1.76/1,000	1.76/1,000	CD
cord-005603-kjcbbgse	63	23	hospital	hospital	NN
cord-005603-kjcbbgse	63	24	discharges	discharge	NNS
cord-005603-kjcbbgse	63	25	between	between	IN
cord-005603-kjcbbgse	63	26	1979	1979	CD
cord-005603-kjcbbgse	63	27	to	to	IN
cord-005603-kjcbbgse	63	28	1987	1987	CD
cord-005603-kjcbbgse	63	29	[	[	-LRB-
cord-005603-kjcbbgse	63	30	3	3	CD
cord-005603-kjcbbgse	63	31	]	]	-RRB-
cord-005603-kjcbbgse	63	32	.	.	.
cord-005603-kjcbbgse	64	1	Much	much	JJ
cord-005603-kjcbbgse	64	2	±	±	NNP
cord-005603-kjcbbgse	64	3	if	if	IN
cord-005603-kjcbbgse	64	4	not	not	RB
cord-005603-kjcbbgse	64	5	all	all	DT
cord-005603-kjcbbgse	64	6	±	±	NNP
cord-005603-kjcbbgse	64	7	this	this	DT
cord-005603-kjcbbgse	64	8	change	change	NN
cord-005603-kjcbbgse	64	9	is	be	VBZ
cord-005603-kjcbbgse	64	10	caused	cause	VBN
cord-005603-kjcbbgse	64	11	by	by	IN
cord-005603-kjcbbgse	64	12	the	the	DT
cord-005603-kjcbbgse	64	13	increasing	increase	VBG
cord-005603-kjcbbgse	64	14	importance	importance	NN
cord-005603-kjcbbgse	64	15	of	of	IN
cord-005603-kjcbbgse	64	16	nosocomial	nosocomial	JJ
cord-005603-kjcbbgse	64	17	infection	infection	NN
cord-005603-kjcbbgse	64	18	.	.	.
cord-005603-kjcbbgse	65	1	At	at	IN
cord-005603-kjcbbgse	65	2	one	one	CD
cord-005603-kjcbbgse	65	3	tertiary	tertiary	JJ
cord-005603-kjcbbgse	65	4	-	-	HYPH
cord-005603-kjcbbgse	65	5	care	care	NN
cord-005603-kjcbbgse	65	6	institution	institution	NN
cord-005603-kjcbbgse	65	7	,	,	,
cord-005603-kjcbbgse	65	8	the	the	DT
cord-005603-kjcbbgse	65	9	rate	rate	NN
cord-005603-kjcbbgse	65	10	of	of	IN
cord-005603-kjcbbgse	65	11	nosocomial	nosocomial	JJ
cord-005603-kjcbbgse	65	12	bacteraemia	bacteraemia	NNP
cord-005603-kjcbbgse	65	13	has	have	VBZ
cord-005603-kjcbbgse	65	14	increased	increase	VBN
cord-005603-kjcbbgse	65	15	steadily	steadily	RB
cord-005603-kjcbbgse	65	16	from	from	IN
cord-005603-kjcbbgse	65	17	6.7/1,000	6.7/1,000	CD
cord-005603-kjcbbgse	65	18	to	to	IN
cord-005603-kjcbbgse	65	19	18.4/1,000	18.4/1,000	CD
cord-005603-kjcbbgse	65	20	discharges	discharge	NNS
cord-005603-kjcbbgse	65	21	between	between	IN
cord-005603-kjcbbgse	65	22	1980	1980	CD
cord-005603-kjcbbgse	65	23	and	and	CC
cord-005603-kjcbbgse	65	24	1992	1992	CD
cord-005603-kjcbbgse	65	25	[	[	-LRB-
cord-005603-kjcbbgse	65	26	4	4	CD
cord-005603-kjcbbgse	65	27	]	]	-RRB-
cord-005603-kjcbbgse	65	28	.	.	.
cord-005603-kjcbbgse	66	1	In	in	IN
cord-005603-kjcbbgse	66	2	the	the	DT
cord-005603-kjcbbgse	66	3	French	french	JJ
cord-005603-kjcbbgse	66	4	multi	multi	JJ
cord-005603-kjcbbgse	66	5	-	-	JJ
cord-005603-kjcbbgse	66	6	center	center	JJ
cord-005603-kjcbbgse	66	7	study	study	NN
cord-005603-kjcbbgse	66	8	conducted	conduct	VBN
cord-005603-kjcbbgse	66	9	in	in	IN
cord-005603-kjcbbgse	66	10	1993	1993	CD
cord-005603-kjcbbgse	66	11	in	in	IN
cord-005603-kjcbbgse	66	12	24	24	CD
cord-005603-kjcbbgse	66	13	public	public	JJ
cord-005603-kjcbbgse	66	14	or	or	CC
cord-005603-kjcbbgse	66	15	public	public	JJ
cord-005603-kjcbbgse	66	16	-	-	HYPH
cord-005603-kjcbbgse	66	17	affiliated	affiliate	VBN
cord-005603-kjcbbgse	66	18	hospitals	hospital	NNS
cord-005603-kjcbbgse	66	19	[	[	-LRB-
cord-005603-kjcbbgse	66	20	5	5	CD
cord-005603-kjcbbgse	66	21	]	]	-RRB-
cord-005603-kjcbbgse	66	22	we	-PRON-	PRP
cord-005603-kjcbbgse	66	23	recorded	record	VBD
cord-005603-kjcbbgse	66	24	an	an	DT
cord-005603-kjcbbgse	66	25	overall	overall	JJ
cord-005603-kjcbbgse	66	26	incidence	incidence	NN
cord-005603-kjcbbgse	66	27	rate	rate	NN
cord-005603-kjcbbgse	66	28	of	of	IN
cord-005603-kjcbbgse	66	29	bacteraemia	bacteraemia	NN
cord-005603-kjcbbgse	66	30	of	of	IN
cord-005603-kjcbbgse	66	31	9.8	9.8	CD
cord-005603-kjcbbgse	66	32	(	(	-LRB-
cord-005603-kjcbbgse	66	33	95	95	CD
cord-005603-kjcbbgse	66	34	CI	CI	NNP
cord-005603-kjcbbgse	66	35	9.2	9.2	CD
cord-005603-kjcbbgse	66	36	to	to	IN
cord-005603-kjcbbgse	66	37	10.5	10.5	CD
cord-005603-kjcbbgse	66	38	)	)	-RRB-
cord-005603-kjcbbgse	66	39	per	per	IN
cord-005603-kjcbbgse	66	40	1,000	1,000	CD
cord-005603-kjcbbgse	66	41	admissions	admission	NNS
cord-005603-kjcbbgse	66	42	;	;	:
cord-005603-kjcbbgse	66	43	this	this	DT
cord-005603-kjcbbgse	66	44	rate	rate	NN
cord-005603-kjcbbgse	66	45	was	be	VBD
cord-005603-kjcbbgse	66	46	more	more	JJR
cord-005603-kjcbbgse	66	47	than	than	IN
cord-005603-kjcbbgse	66	48	eight	eight	CD
cord-005603-kjcbbgse	66	49	-	-	RB
cord-005603-kjcbbgse	66	50	fold	fold	VB
cord-005603-kjcbbgse	66	51	higher	higher	RBR
cord-005603-kjcbbgse	66	52	in	in	IN
cord-005603-kjcbbgse	66	53	ICUs	ICUs	NNP
cord-005603-kjcbbgse	66	54	(	(	-LRB-
cord-005603-kjcbbgse	66	55	69/1,000	69/1,000	CD
cord-005603-kjcbbgse	66	56	)	)	-RRB-
cord-005603-kjcbbgse	66	57	than	than	IN
cord-005603-kjcbbgse	66	58	in	in	IN
cord-005603-kjcbbgse	66	59	wards	ward	NNS
cord-005603-kjcbbgse	66	60	(	(	-LRB-
cord-005603-kjcbbgse	66	61	8.2/1,000	8.2/1,000	CD
cord-005603-kjcbbgse	66	62	)	)	-RRB-
cord-005603-kjcbbgse	67	1	(	(	-LRB-
cord-005603-kjcbbgse	67	2	Table	table	NN
cord-005603-kjcbbgse	67	3	2	2	CD
cord-005603-kjcbbgse	67	4	)	)	-RRB-
cord-005603-kjcbbgse	67	5	.	.	.
cord-005603-kjcbbgse	68	1	Of	of	IN
cord-005603-kjcbbgse	68	2	the	the	DT
cord-005603-kjcbbgse	68	3	842	842	CD
cord-005603-kjcbbgse	68	4	bacteraemic	bacteraemic	NNP
cord-005603-kjcbbgse	68	5	episodes	episode	NNS
cord-005603-kjcbbgse	68	6	recorded	record	VBN
cord-005603-kjcbbgse	68	7	in	in	IN
cord-005603-kjcbbgse	68	8	this	this	DT
cord-005603-kjcbbgse	68	9	study	study	NN
cord-005603-kjcbbgse	68	10	,	,	,
cord-005603-kjcbbgse	68	11	19	19	CD
cord-005603-kjcbbgse	68	12	%	%	NN
cord-005603-kjcbbgse	68	13	occurred	occur	VBD
cord-005603-kjcbbgse	68	14	in	in	IN
cord-005603-kjcbbgse	68	15	ICUs	ICUs	NNP
cord-005603-kjcbbgse	68	16	,	,	,
cord-005603-kjcbbgse	68	17	63	63	CD
cord-005603-kjcbbgse	68	18	%	%	NN
cord-005603-kjcbbgse	68	19	in	in	IN
cord-005603-kjcbbgse	68	20	medical	medical	JJ
cord-005603-kjcbbgse	68	21	wards	ward	NNS
cord-005603-kjcbbgse	68	22	,	,	,
cord-005603-kjcbbgse	68	23	and	and	CC
cord-005603-kjcbbgse	68	24	18	18	CD
cord-005603-kjcbbgse	68	25	%	%	NN
cord-005603-kjcbbgse	68	26	in	in	IN
cord-005603-kjcbbgse	68	27	surgical	surgical	JJ
cord-005603-kjcbbgse	68	28	wards	ward	NNS
cord-005603-kjcbbgse	68	29	.	.	.
cord-005603-kjcbbgse	69	1	Extrapolating	extrapolate	VBG
cord-005603-kjcbbgse	69	2	these	these	DT
cord-005603-kjcbbgse	69	3	results	result	NNS
cord-005603-kjcbbgse	69	4	to	to	IN
cord-005603-kjcbbgse	69	5	the	the	DT
cord-005603-kjcbbgse	69	6	whole	whole	JJ
cord-005603-kjcbbgse	69	7	country	country	NN
cord-005603-kjcbbgse	69	8	would	would	MD
cord-005603-kjcbbgse	69	9	give	give	VB
cord-005603-kjcbbgse	69	10	a	a	DT
cord-005603-kjcbbgse	69	11	figure	figure	NN
cord-005603-kjcbbgse	69	12	of	of	IN
cord-005603-kjcbbgse	69	13	approximately	approximately	RB
cord-005603-kjcbbgse	69	14	67,500	67,500	CD
cord-005603-kjcbbgse	69	15	bacteraemic	bacteraemic	NNP
cord-005603-kjcbbgse	69	16	episodes	episode	NNS
cord-005603-kjcbbgse	69	17	occurring	occur	VBG
cord-005603-kjcbbgse	69	18	annually	annually	RB
cord-005603-kjcbbgse	69	19	,	,	,
cord-005603-kjcbbgse	69	20	of	of	IN
cord-005603-kjcbbgse	69	21	which	which	WDT
cord-005603-kjcbbgse	69	22	13,500	13,500	CD
cord-005603-kjcbbgse	69	23	would	would	MD
cord-005603-kjcbbgse	69	24	occur	occur	VB
cord-005603-kjcbbgse	69	25	in	in	IN
cord-005603-kjcbbgse	69	26	ICUs	ICUs	NNP
cord-005603-kjcbbgse	69	27	.	.	.
cord-005603-kjcbbgse	70	1	So	so	RB
cord-005603-kjcbbgse	70	2	far	far	RB
cord-005603-kjcbbgse	70	3	,	,	,
cord-005603-kjcbbgse	70	4	the	the	DT
cord-005603-kjcbbgse	70	5	most	most	RBS
cord-005603-kjcbbgse	70	6	comprehensive	comprehensive	JJ
cord-005603-kjcbbgse	70	7	study	study	NN
cord-005603-kjcbbgse	70	8	on	on	IN
cord-005603-kjcbbgse	70	9	the	the	DT
cord-005603-kjcbbgse	70	10	clinical	clinical	JJ
cord-005603-kjcbbgse	70	11	significance	significance	NN
cord-005603-kjcbbgse	70	12	of	of	IN
cord-005603-kjcbbgse	70	13	the	the	DT
cord-005603-kjcbbgse	70	14	early	early	JJ
cord-005603-kjcbbgse	70	15	stages	stage	NNS
cord-005603-kjcbbgse	70	16	of	of	IN
cord-005603-kjcbbgse	70	17	the	the	DT
cord-005603-kjcbbgse	70	18	septic	septic	JJ
cord-005603-kjcbbgse	70	19	syndromes	syndrome	NNS
cord-005603-kjcbbgse	70	20	was	be	VBD
cord-005603-kjcbbgse	70	21	conducted	conduct	VBN
cord-005603-kjcbbgse	70	22	by	by	IN
cord-005603-kjcbbgse	70	23	Rangel	Rangel	NNP
cord-005603-kjcbbgse	70	24	-	-	HYPH
cord-005603-kjcbbgse	70	25	Fausto	Fausto	NNP
cord-005603-kjcbbgse	70	26	et	et	NNP
cord-005603-kjcbbgse	70	27	al	al	NNP
cord-005603-kjcbbgse	70	28	.	.	.
cord-005603-kjcbbgse	71	1	at	at	IN
cord-005603-kjcbbgse	71	2	the	the	DT
cord-005603-kjcbbgse	71	3	University	University	NNP
cord-005603-kjcbbgse	71	4	of	of	IN
cord-005603-kjcbbgse	71	5	Iowa	Iowa	NNP
cord-005603-kjcbbgse	71	6	Hospital	Hospital	NNP
cord-005603-kjcbbgse	71	7	and	and	CC
cord-005603-kjcbbgse	71	8	Clinics	Clinics	NNP
cord-005603-kjcbbgse	71	9	[	[	-LRB-
cord-005603-kjcbbgse	71	10	6	6	CD
cord-005603-kjcbbgse	71	11	]	]	-RRB-
cord-005603-kjcbbgse	71	12	.	.	.
cord-005603-kjcbbgse	72	1	This	this	DT
cord-005603-kjcbbgse	72	2	study	study	NN
cord-005603-kjcbbgse	72	3	was	be	VBD
cord-005603-kjcbbgse	72	4	performed	perform	VBN
cord-005603-kjcbbgse	72	5	in	in	IN
cord-005603-kjcbbgse	72	6	three	three	CD
cord-005603-kjcbbgse	72	7	ICUs	icu	NNS
cord-005603-kjcbbgse	72	8	(	(	-LRB-
cord-005603-kjcbbgse	72	9	medical	medical	JJ
cord-005603-kjcbbgse	72	10	,	,	,
cord-005603-kjcbbgse	72	11	surgical	surgical	JJ
cord-005603-kjcbbgse	72	12	,	,	,
cord-005603-kjcbbgse	72	13	and	and	CC
cord-005603-kjcbbgse	72	14	cardiovascular	cardiovascular	JJ
cord-005603-kjcbbgse	72	15	)	)	-RRB-
cord-005603-kjcbbgse	72	16	and	and	CC
cord-005603-kjcbbgse	72	17	3	3	CD
cord-005603-kjcbbgse	72	18	wards	ward	NNS
cord-005603-kjcbbgse	72	19	of	of	IN
cord-005603-kjcbbgse	72	20	a	a	DT
cord-005603-kjcbbgse	72	21	900-bed	900-bed	CD
cord-005603-kjcbbgse	72	22	teaching	teaching	NN
cord-005603-kjcbbgse	72	23	hospital	hospital	NN
cord-005603-kjcbbgse	72	24	including	include	VBG
cord-005603-kjcbbgse	72	25	200	200	CD
cord-005603-kjcbbgse	72	26	ICU	ICU	NNP
cord-005603-kjcbbgse	72	27	beds	bed	NNS
cord-005603-kjcbbgse	72	28	.	.	.
cord-005603-kjcbbgse	73	1	The	the	DT
cord-005603-kjcbbgse	73	2	incidence	incidence	NN
cord-005603-kjcbbgse	73	3	of	of	IN
cord-005603-kjcbbgse	73	4	SIRS	SIRS	NNP
cord-005603-kjcbbgse	73	5	,	,	,
cord-005603-kjcbbgse	73	6	sepsis	sepsis	NN
cord-005603-kjcbbgse	73	7	,	,	,
cord-005603-kjcbbgse	73	8	and	and	CC
cord-005603-kjcbbgse	73	9	severe	severe	JJ
cord-005603-kjcbbgse	73	10	sepsis	sepsis	NN
cord-005603-kjcbbgse	73	11	and	and	CC
cord-005603-kjcbbgse	73	12	septic	septic	JJ
cord-005603-kjcbbgse	73	13	shock	shock	NN
cord-005603-kjcbbgse	73	14	was	be	VBD
cord-005603-kjcbbgse	73	15	assessed	assess	VBN
cord-005603-kjcbbgse	73	16	during	during	IN
cord-005603-kjcbbgse	73	17	a	a	DT
cord-005603-kjcbbgse	73	18	9-month	9-month	JJ
cord-005603-kjcbbgse	73	19	period	period	NN
cord-005603-kjcbbgse	73	20	,	,	,
cord-005603-kjcbbgse	73	21	including	include	VBG
cord-005603-kjcbbgse	73	22	a	a	DT
cord-005603-kjcbbgse	73	23	follow	follow	VB
cord-005603-kjcbbgse	73	24	-	-	HYPH
cord-005603-kjcbbgse	73	25	up	up	NN
cord-005603-kjcbbgse	73	26	period	period	NN
cord-005603-kjcbbgse	73	27	of	of	IN
cord-005603-kjcbbgse	73	28	up	up	IN
cord-005603-kjcbbgse	73	29	to	to	TO
cord-005603-kjcbbgse	73	30	28	28	CD
cord-005603-kjcbbgse	73	31	days	day	NNS
cord-005603-kjcbbgse	73	32	.	.	.
cord-005603-kjcbbgse	74	1	Of	of	IN
cord-005603-kjcbbgse	74	2	the	the	DT
cord-005603-kjcbbgse	74	3	3708	3708	CD
cord-005603-kjcbbgse	74	4	patients	patient	NNS
cord-005603-kjcbbgse	74	5	admitted	admit	VBD
cord-005603-kjcbbgse	74	6	during	during	IN
cord-005603-kjcbbgse	74	7	the	the	DT
cord-005603-kjcbbgse	74	8	study	study	NN
cord-005603-kjcbbgse	74	9	period	period	NN
cord-005603-kjcbbgse	74	10	,	,	,
cord-005603-kjcbbgse	74	11	S	S	NNP
cord-005603-kjcbbgse	74	12	66	66	CD
cord-005603-kjcbbgse	74	13	Data	datum	NNS
cord-005603-kjcbbgse	74	14	are	be	VBP
cord-005603-kjcbbgse	74	15	reported	report	VBN
cord-005603-kjcbbgse	74	16	with	with	IN
cord-005603-kjcbbgse	74	17	95	95	CD
cord-005603-kjcbbgse	74	18	%	%	NN
cord-005603-kjcbbgse	74	19	confidence	confidence	NN
cord-005603-kjcbbgse	74	20	intervals	interval	NNS
cord-005603-kjcbbgse	74	21	in	in	IN
cord-005603-kjcbbgse	74	22	brackets	bracket	NNS
cord-005603-kjcbbgse	74	23	,	,	,
cord-005603-kjcbbgse	74	24	when	when	WRB
cord-005603-kjcbbgse	74	25	available	available	JJ
cord-005603-kjcbbgse	74	26	.	.	.
cord-005603-kjcbbgse	75	1	NA	NA	NNP
cord-005603-kjcbbgse	75	2	=	=	NFP
cord-005603-kjcbbgse	75	3	not	not	RB
cord-005603-kjcbbgse	75	4	available	available	JJ
cord-005603-kjcbbgse	75	5	(	(	-LRB-
cord-005603-kjcbbgse	75	6	1	1	CD
cord-005603-kjcbbgse	75	7	)	)	-RRB-
cord-005603-kjcbbgse	75	8	2-month	2-month	JJ
cord-005603-kjcbbgse	75	9	incidence	incidence	NN
cord-005603-kjcbbgse	75	10	study	study	NN
cord-005603-kjcbbgse	75	11	in	in	IN
cord-005603-kjcbbgse	75	12	24	24	CD
cord-005603-kjcbbgse	75	13	hospitals	hospital	NNS
cord-005603-kjcbbgse	75	14	in	in	IN
cord-005603-kjcbbgse	75	15	France	France	NNP
cord-005603-kjcbbgse	75	16	;	;	:
cord-005603-kjcbbgse	75	17	(	(	-LRB-
cord-005603-kjcbbgse	75	18	2	2	LS
cord-005603-kjcbbgse	75	19	)	)	-RRB-
cord-005603-kjcbbgse	75	20	Survey	survey	VB
cord-005603-kjcbbgse	75	21	at	at	IN
cord-005603-kjcbbgse	75	22	8	8	CD
cord-005603-kjcbbgse	75	23	academic	academic	JJ
cord-005603-kjcbbgse	75	24	medical	medical	JJ
cord-005603-kjcbbgse	75	25	centres	centre	NNS
cord-005603-kjcbbgse	75	26	in	in	IN
cord-005603-kjcbbgse	75	27	the	the	DT
cord-005603-kjcbbgse	75	28	US	US	NNP
cord-005603-kjcbbgse	75	29	;	;	:
cord-005603-kjcbbgse	75	30	(	(	-LRB-
cord-005603-kjcbbgse	75	31	3	3	LS
cord-005603-kjcbbgse	75	32	)	)	-RRB-
cord-005603-kjcbbgse	75	33	Incidence	incidence	NN
cord-005603-kjcbbgse	75	34	study	study	NN
cord-005603-kjcbbgse	75	35	at	at	IN
cord-005603-kjcbbgse	75	36	one	one	CD
cord-005603-kjcbbgse	75	37	academic	academic	JJ
cord-005603-kjcbbgse	75	38	centre	centre	NN
cord-005603-kjcbbgse	75	39	in	in	IN
cord-005603-kjcbbgse	75	40	the	the	DT
cord-005603-kjcbbgse	75	41	Netherlands	Netherlands	NNP
cord-005603-kjcbbgse	75	42	;	;	:
cord-005603-kjcbbgse	75	43	(	(	-LRB-
cord-005603-kjcbbgse	75	44	4	4	LS
cord-005603-kjcbbgse	75	45	)	)	-RRB-
cord-005603-kjcbbgse	76	1	Prevalence	prevalence	NN
cord-005603-kjcbbgse	76	2	survey	survey	NN
cord-005603-kjcbbgse	76	3	at	at	IN
cord-005603-kjcbbgse	76	4	one	one	CD
cord-005603-kjcbbgse	76	5	academic	academic	JJ
cord-005603-kjcbbgse	76	6	medical	medical	JJ
cord-005603-kjcbbgse	76	7	centre	centre	NN
cord-005603-kjcbbgse	76	8	in	in	IN
cord-005603-kjcbbgse	76	9	the	the	DT
cord-005603-kjcbbgse	76	10	US	US	NNP
cord-005603-kjcbbgse	76	11	;	;	:
cord-005603-kjcbbgse	76	12	(	(	-LRB-
cord-005603-kjcbbgse	76	13	5	5	LS
cord-005603-kjcbbgse	76	14	)	)	-RRB-
cord-005603-kjcbbgse	77	1	Prevalence	prevalence	NN
cord-005603-kjcbbgse	77	2	survey	survey	NN
cord-005603-kjcbbgse	77	3	at	at	IN
cord-005603-kjcbbgse	77	4	n	n	CD
cord-005603-kjcbbgse	77	5	hospitals	hospital	NNS
cord-005603-kjcbbgse	77	6	in	in	IN
cord-005603-kjcbbgse	77	7	Italy	Italy	NNP
cord-005603-kjcbbgse	77	8	;	;	:
cord-005603-kjcbbgse	78	1	(	(	-LRB-
cord-005603-kjcbbgse	78	2	6	6	LS
cord-005603-kjcbbgse	78	3	)	)	-RRB-
cord-005603-kjcbbgse	78	4	Incidence	incidence	NN
cord-005603-kjcbbgse	78	5	of	of	IN
cord-005603-kjcbbgse	78	6	bacteremic	bacteremic	JJ
cord-005603-kjcbbgse	78	7	sepsis	sepsis	NN
cord-005603-kjcbbgse	78	8	only	only	RB
cord-005603-kjcbbgse	78	9	at	at	IN
cord-005603-kjcbbgse	78	10	one	one	CD
cord-005603-kjcbbgse	78	11	academic	academic	JJ
cord-005603-kjcbbgse	78	12	medical	medical	JJ
cord-005603-kjcbbgse	78	13	centre	centre	NN
cord-005603-kjcbbgse	78	14	in	in	IN
cord-005603-kjcbbgse	78	15	Switzerland	Switzerland	NNP
cord-005603-kjcbbgse	78	16	a	a	DT
cord-005603-kjcbbgse	78	17	Incidence/1,000	Incidence/1,000	NNP
cord-005603-kjcbbgse	78	18	admissions	admission	NNS
cord-005603-kjcbbgse	78	19	;	;	:
cord-005603-kjcbbgse	78	20	b	b	LS
cord-005603-kjcbbgse	78	21	incidence/1,000	incidence/1,000	NN
cord-005603-kjcbbgse	78	22	patient	patient	NN
cord-005603-kjcbbgse	78	23	-	-	HYPH
cord-005603-kjcbbgse	78	24	days	day	NNS
cord-005603-kjcbbgse	78	25	2527	2527	CD
cord-005603-kjcbbgse	78	26	(	(	-LRB-
cord-005603-kjcbbgse	78	27	68	68	CD
cord-005603-kjcbbgse	78	28	%	%	NN
cord-005603-kjcbbgse	78	29	)	)	-RRB-
cord-005603-kjcbbgse	78	30	met	meet	VBD
cord-005603-kjcbbgse	78	31	at	at	RB
cord-005603-kjcbbgse	78	32	least	least	RBS
cord-005603-kjcbbgse	78	33	two	two	CD
cord-005603-kjcbbgse	78	34	criteria	criterion	NNS
cord-005603-kjcbbgse	78	35	for	for	IN
cord-005603-kjcbbgse	78	36	SIRS	sir	NNS
cord-005603-kjcbbgse	78	37	at	at	IN
cord-005603-kjcbbgse	78	38	some	some	DT
cord-005603-kjcbbgse	78	39	point	point	NN
cord-005603-kjcbbgse	78	40	in	in	IN
cord-005603-kjcbbgse	78	41	their	-PRON-	PRP$
cord-005603-kjcbbgse	78	42	hospital	hospital	NN
cord-005603-kjcbbgse	78	43	stay	stay	NN
cord-005603-kjcbbgse	78	44	[	[	-LRB-
cord-005603-kjcbbgse	78	45	6	6	CD
cord-005603-kjcbbgse	78	46	<	<	XX
cord-005603-kjcbbgse	78	47	]	]	-RRB-
cord-005603-kjcbbgse	78	48	.	.	.
cord-005603-kjcbbgse	79	1	The	the	DT
cord-005603-kjcbbgse	79	2	major	major	JJ
cord-005603-kjcbbgse	79	3	finding	finding	NN
cord-005603-kjcbbgse	79	4	from	from	IN
cord-005603-kjcbbgse	79	5	this	this	DT
cord-005603-kjcbbgse	79	6	study	study	NN
cord-005603-kjcbbgse	79	7	was	be	VBD
cord-005603-kjcbbgse	79	8	that	that	IN
cord-005603-kjcbbgse	79	9	medical	medical	JJ
cord-005603-kjcbbgse	79	10	or	or	CC
cord-005603-kjcbbgse	79	11	surgical	surgical	JJ
cord-005603-kjcbbgse	79	12	ICU	ICU	NNP
cord-005603-kjcbbgse	79	13	patients	patient	NNS
cord-005603-kjcbbgse	79	14	met	meet	VBD
cord-005603-kjcbbgse	79	15	2	2	CD
cord-005603-kjcbbgse	79	16	or	or	CC
cord-005603-kjcbbgse	79	17	more	more	JJR
cord-005603-kjcbbgse	79	18	SIRS	sirs	JJ
cord-005603-kjcbbgse	79	19	criteria	criterion	NNS
cord-005603-kjcbbgse	79	20	during	during	IN
cord-005603-kjcbbgse	79	21	>	>	XX
cord-005603-kjcbbgse	79	22	80	80	CD
cord-005603-kjcbbgse	79	23	%	%	NN
cord-005603-kjcbbgse	79	24	of	of	IN
cord-005603-kjcbbgse	79	25	their	-PRON-	PRP$
cord-005603-kjcbbgse	79	26	unit	unit	NN
cord-005603-kjcbbgse	79	27	stay	stay	VB
cord-005603-kjcbbgse	79	28	,	,	,
cord-005603-kjcbbgse	79	29	whereas	whereas	IN
cord-005603-kjcbbgse	79	30	patients	patient	NNS
cord-005603-kjcbbgse	79	31	in	in	IN
cord-005603-kjcbbgse	79	32	the	the	DT
cord-005603-kjcbbgse	79	33	cardiovascular	cardiovascular	JJ
cord-005603-kjcbbgse	79	34	ICU	ICU	NNP
cord-005603-kjcbbgse	79	35	met	meet	VBD
cord-005603-kjcbbgse	79	36	such	such	JJ
cord-005603-kjcbbgse	79	37	criteria	criterion	NNS
cord-005603-kjcbbgse	79	38	during	during	IN
cord-005603-kjcbbgse	79	39	slightly	slightly	RB
cord-005603-kjcbbgse	79	40	over	over	IN
cord-005603-kjcbbgse	79	41	one	one	CD
cord-005603-kjcbbgse	79	42	-	-	HYPH
cord-005603-kjcbbgse	79	43	half	half	NN
cord-005603-kjcbbgse	79	44	of	of	IN
cord-005603-kjcbbgse	79	45	their	-PRON-	PRP$
cord-005603-kjcbbgse	79	46	unit	unit	NN
cord-005603-kjcbbgse	79	47	stay	stay	VB
cord-005603-kjcbbgse	79	48	,	,	,
cord-005603-kjcbbgse	79	49	and	and	CC
cord-005603-kjcbbgse	79	50	patients	patient	NNS
cord-005603-kjcbbgse	79	51	from	from	IN
cord-005603-kjcbbgse	79	52	other	other	JJ
cord-005603-kjcbbgse	79	53	wards	ward	NNS
cord-005603-kjcbbgse	79	54	from	from	IN
cord-005603-kjcbbgse	79	55	32	32	CD
cord-005603-kjcbbgse	79	56	%	%	NN
cord-005603-kjcbbgse	79	57	to	to	TO
cord-005603-kjcbbgse	79	58	67	67	CD
cord-005603-kjcbbgse	79	59	%	%	NN
cord-005603-kjcbbgse	79	60	of	of	IN
cord-005603-kjcbbgse	79	61	their	-PRON-	PRP$
cord-005603-kjcbbgse	79	62	stay	stay	NN
cord-005603-kjcbbgse	79	63	.	.	.
cord-005603-kjcbbgse	80	1	It	-PRON-	PRP
cord-005603-kjcbbgse	80	2	should	should	MD
cord-005603-kjcbbgse	80	3	be	be	VB
cord-005603-kjcbbgse	80	4	noted	note	VBN
cord-005603-kjcbbgse	80	5	however	however	RB
cord-005603-kjcbbgse	80	6	,	,	,
cord-005603-kjcbbgse	80	7	that	that	IN
cord-005603-kjcbbgse	80	8	the	the	DT
cord-005603-kjcbbgse	80	9	wards	ward	NNS
cord-005603-kjcbbgse	80	10	surveyed	survey	VBN
cord-005603-kjcbbgse	80	11	likely	likely	RB
cord-005603-kjcbbgse	80	12	housed	house	VBD
cord-005603-kjcbbgse	80	13	a	a	DT
cord-005603-kjcbbgse	80	14	population	population	NN
cord-005603-kjcbbgse	80	15	at	at	IN
cord-005603-kjcbbgse	80	16	unusually	unusually	RB
cord-005603-kjcbbgse	80	17	high	high	JJ
cord-005603-kjcbbgse	80	18	risk	risk	NN
cord-005603-kjcbbgse	80	19	of	of	IN
cord-005603-kjcbbgse	80	20	sepsis	sepsis	NN
cord-005603-kjcbbgse	80	21	,	,	,
cord-005603-kjcbbgse	80	22	as	as	IN
cord-005603-kjcbbgse	80	23	indicated	indicate	VBN
cord-005603-kjcbbgse	80	24	by	by	IN
cord-005603-kjcbbgse	80	25	the	the	DT
cord-005603-kjcbbgse	80	26	two	two	CD
cord-005603-kjcbbgse	80	27	prevalence	prevalence	NN
cord-005603-kjcbbgse	80	28	surveys	survey	NNS
cord-005603-kjcbbgse	80	29	done	do	VBN
cord-005603-kjcbbgse	80	30	to	to	TO
cord-005603-kjcbbgse	80	31	complement	complement	VB
cord-005603-kjcbbgse	80	32	the	the	DT
cord-005603-kjcbbgse	80	33	incidence	incidence	NN
cord-005603-kjcbbgse	80	34	study	study	NN
cord-005603-kjcbbgse	80	35	.	.	.
cord-005603-kjcbbgse	81	1	In	in	IN
cord-005603-kjcbbgse	81	2	these	these	DT
cord-005603-kjcbbgse	81	3	surveys	survey	NNS
cord-005603-kjcbbgse	81	4	including	include	VBG
cord-005603-kjcbbgse	81	5	all	all	DT
cord-005603-kjcbbgse	81	6	hospital	hospital	NN
cord-005603-kjcbbgse	81	7	wards	ward	NNS
cord-005603-kjcbbgse	81	8	,	,	,
cord-005603-kjcbbgse	81	9	the	the	DT
cord-005603-kjcbbgse	81	10	prevalence	prevalence	NN
cord-005603-kjcbbgse	81	11	of	of	IN
cord-005603-kjcbbgse	81	12	SIRS	SIRS	NNP
cord-005603-kjcbbgse	81	13	was	be	VBD
cord-005603-kjcbbgse	81	14	about	about	RB
cord-005603-kjcbbgse	81	15	twice	twice	RB
cord-005603-kjcbbgse	81	16	higher	high	JJR
cord-005603-kjcbbgse	81	17	(	(	-LRB-
cord-005603-kjcbbgse	81	18	64	64	CD
cord-005603-kjcbbgse	81	19	%	%	NN
cord-005603-kjcbbgse	81	20	and	and	CC
cord-005603-kjcbbgse	81	21	61	61	CD
cord-005603-kjcbbgse	81	22	%	%	NN
cord-005603-kjcbbgse	81	23	)	)	-RRB-
cord-005603-kjcbbgse	81	24	in	in	IN
cord-005603-kjcbbgse	81	25	the	the	DT
cord-005603-kjcbbgse	81	26	3	3	CD
cord-005603-kjcbbgse	81	27	wards	ward	NNS
cord-005603-kjcbbgse	81	28	participating	participate	VBG
cord-005603-kjcbbgse	81	29	in	in	IN
cord-005603-kjcbbgse	81	30	the	the	DT
cord-005603-kjcbbgse	81	31	incidence	incidence	NN
cord-005603-kjcbbgse	81	32	study	study	NN
cord-005603-kjcbbgse	81	33	than	than	IN
cord-005603-kjcbbgse	81	34	that	that	DT
cord-005603-kjcbbgse	81	35	recorded	record	VBN
cord-005603-kjcbbgse	81	36	in	in	IN
cord-005603-kjcbbgse	81	37	the	the	DT
cord-005603-kjcbbgse	81	38	27	27	CD
cord-005603-kjcbbgse	81	39	other	other	JJ
cord-005603-kjcbbgse	81	40	wards	ward	NNS
cord-005603-kjcbbgse	81	41	(	(	-LRB-
cord-005603-kjcbbgse	81	42	25	25	CD
cord-005603-kjcbbgse	81	43	%	%	NN
cord-005603-kjcbbgse	81	44	and	and	CC
cord-005603-kjcbbgse	81	45	27	27	CD
cord-005603-kjcbbgse	81	46	%	%	NN
cord-005603-kjcbbgse	81	47	)	)	-RRB-
cord-005603-kjcbbgse	82	1	(	(	-LRB-
cord-005603-kjcbbgse	82	2	Table	table	NN
cord-005603-kjcbbgse	82	3	2	2	CD
cord-005603-kjcbbgse	82	4	)	)	-RRB-
cord-005603-kjcbbgse	82	5	.	.	.
cord-005603-kjcbbgse	83	1	The	the	DT
cord-005603-kjcbbgse	83	2	prevalence	prevalence	NN
cord-005603-kjcbbgse	83	3	of	of	IN
cord-005603-kjcbbgse	83	4	sepsis	sepsis	NN
cord-005603-kjcbbgse	83	5	was	be	VBD
cord-005603-kjcbbgse	83	6	of	of	IN
cord-005603-kjcbbgse	83	7	6	6	CD
cord-005603-kjcbbgse	83	8	%	%	NN
cord-005603-kjcbbgse	83	9	±8	±8	NNS
cord-005603-kjcbbgse	83	10	%	%	NN
cord-005603-kjcbbgse	83	11	in	in	IN
cord-005603-kjcbbgse	83	12	the	the	DT
cord-005603-kjcbbgse	83	13	latter	latter	JJ
cord-005603-kjcbbgse	83	14	wards	ward	NNS
cord-005603-kjcbbgse	83	15	,	,	,
cord-005603-kjcbbgse	83	16	and	and	CC
cord-005603-kjcbbgse	83	17	that	that	DT
cord-005603-kjcbbgse	83	18	of	of	IN
cord-005603-kjcbbgse	83	19	severe	severe	JJ
cord-005603-kjcbbgse	83	20	sepsis	sepsis	NN
cord-005603-kjcbbgse	83	21	and	and	CC
cord-005603-kjcbbgse	83	22	shock	shock	NN
cord-005603-kjcbbgse	83	23	was	be	VBD
cord-005603-kjcbbgse	83	24	similar	similar	JJ
cord-005603-kjcbbgse	83	25	in	in	IN
cord-005603-kjcbbgse	83	26	both	both	DT
cord-005603-kjcbbgse	83	27	surveys	survey	NNS
cord-005603-kjcbbgse	83	28	in	in	IN
cord-005603-kjcbbgse	83	29	the	the	DT
cord-005603-kjcbbgse	83	30	two	two	CD
cord-005603-kjcbbgse	83	31	categories	category	NNS
cord-005603-kjcbbgse	83	32	of	of	IN
cord-005603-kjcbbgse	83	33	wards	ward	NNS
cord-005603-kjcbbgse	83	34	,	,	,
cord-005603-kjcbbgse	83	35	respectively	respectively	RB
cord-005603-kjcbbgse	83	36	at	at	IN
cord-005603-kjcbbgse	83	37	2	2	CD
cord-005603-kjcbbgse	83	38	%	%	NN
cord-005603-kjcbbgse	83	39	±3	±3	NNP
cord-005603-kjcbbgse	83	40	%	%	NN
cord-005603-kjcbbgse	83	41	,	,	,
cord-005603-kjcbbgse	83	42	and	and	CC
cord-005603-kjcbbgse	83	43	0	0	CD
cord-005603-kjcbbgse	83	44	%	%	NN
cord-005603-kjcbbgse	83	45	.	.	.
cord-005603-kjcbbgse	84	1	Of	of	IN
cord-005603-kjcbbgse	84	2	the	the	DT
cord-005603-kjcbbgse	84	3	2729	2729	CD
cord-005603-kjcbbgse	84	4	episodes	episode	NNS
cord-005603-kjcbbgse	84	5	of	of	IN
cord-005603-kjcbbgse	84	6	septic	septic	JJ
cord-005603-kjcbbgse	84	7	syndromes	syndrome	NNS
cord-005603-kjcbbgse	84	8	(	(	-LRB-
cord-005603-kjcbbgse	84	9	i.	i.	NNP
cord-005603-kjcbbgse	84	10	e.	e.	NNP
cord-005603-kjcbbgse	84	11	,	,	,
cord-005603-kjcbbgse	84	12	at	at	IN
cord-005603-kjcbbgse	84	13	least	least	JJS
cord-005603-kjcbbgse	84	14	SIRS	SIRS	NNP
cord-005603-kjcbbgse	84	15	)	)	-RRB-
cord-005603-kjcbbgse	84	16	recorded	record	VBN
cord-005603-kjcbbgse	84	17	in	in	IN
cord-005603-kjcbbgse	84	18	the	the	DT
cord-005603-kjcbbgse	84	19	incidence	incidence	NN
cord-005603-kjcbbgse	84	20	study	study	NN
cord-005603-kjcbbgse	84	21	,	,	,
cord-005603-kjcbbgse	84	22	1541	1541	CD
cord-005603-kjcbbgse	84	23	(	(	-LRB-
cord-005603-kjcbbgse	84	24	56.4	56.4	CD
cord-005603-kjcbbgse	84	25	%	%	NN
cord-005603-kjcbbgse	84	26	)	)	-RRB-
cord-005603-kjcbbgse	84	27	were	be	VBD
cord-005603-kjcbbgse	84	28	classified	classify	VBN
cord-005603-kjcbbgse	84	29	as	as	IN
cord-005603-kjcbbgse	84	30	sepsis	sepsis	NN
cord-005603-kjcbbgse	84	31	,	,	,
cord-005603-kjcbbgse	84	32	994	994	CD
cord-005603-kjcbbgse	84	33	(	(	-LRB-
cord-005603-kjcbbgse	84	34	36.4	36.4	CD
cord-005603-kjcbbgse	84	35	%	%	NN
cord-005603-kjcbbgse	84	36	)	)	-RRB-
cord-005603-kjcbbgse	84	37	as	as	IN
cord-005603-kjcbbgse	84	38	severe	severe	JJ
cord-005603-kjcbbgse	84	39	sepsis	sepsis	NN
cord-005603-kjcbbgse	84	40	,	,	,
cord-005603-kjcbbgse	84	41	and	and	CC
cord-005603-kjcbbgse	84	42	194	194	CD
cord-005603-kjcbbgse	84	43	(	(	-LRB-
cord-005603-kjcbbgse	84	44	7.1	7.1	CD
cord-005603-kjcbbgse	84	45	%	%	NN
cord-005603-kjcbbgse	84	46	)	)	-RRB-
cord-005603-kjcbbgse	84	47	as	as	IN
cord-005603-kjcbbgse	84	48	septic	septic	JJ
cord-005603-kjcbbgse	84	49	shock	shock	NN
cord-005603-kjcbbgse	84	50	[	[	-LRB-
cord-005603-kjcbbgse	84	51	6	6	CD
cord-005603-kjcbbgse	84	52	]	]	-RRB-
cord-005603-kjcbbgse	84	53	.	.	.
cord-005603-kjcbbgse	85	1	Patients	patient	NNS
cord-005603-kjcbbgse	85	2	with	with	IN
cord-005603-kjcbbgse	85	3	infection	infection	NN
cord-005603-kjcbbgse	85	4	were	be	VBD
cord-005603-kjcbbgse	85	5	classified	classify	VBN
cord-005603-kjcbbgse	85	6	as	as	IN
cord-005603-kjcbbgse	85	7	having	have	VBG
cord-005603-kjcbbgse	85	8	culture	culture	NN
cord-005603-kjcbbgse	85	9	-	-	HYPH
cord-005603-kjcbbgse	85	10	proven	prove	VBN
cord-005603-kjcbbgse	85	11	or	or	CC
cord-005603-kjcbbgse	85	12	culture	culture	NN
cord-005603-kjcbbgse	85	13	-	-	HYPH
cord-005603-kjcbbgse	85	14	negative	negative	JJ
cord-005603-kjcbbgse	85	15	sepsis	sepsis	NN
cord-005603-kjcbbgse	85	16	.	.	.
cord-005603-kjcbbgse	86	1	It	-PRON-	PRP
cord-005603-kjcbbgse	86	2	is	be	VBZ
cord-005603-kjcbbgse	86	3	noteworthy	noteworthy	JJ
cord-005603-kjcbbgse	86	4	that	that	IN
cord-005603-kjcbbgse	86	5	less	less	JJR
cord-005603-kjcbbgse	86	6	than	than	IN
cord-005603-kjcbbgse	86	7	50	50	CD
cord-005603-kjcbbgse	86	8	%	%	NN
cord-005603-kjcbbgse	86	9	of	of	IN
cord-005603-kjcbbgse	86	10	all	all	DT
cord-005603-kjcbbgse	86	11	episodes	episode	NNS
cord-005603-kjcbbgse	86	12	were	be	VBD
cord-005603-kjcbbgse	86	13	microbiologically	microbiologically	RB
cord-005603-kjcbbgse	86	14	documented	document	VBN
cord-005603-kjcbbgse	86	15	,	,	,
cord-005603-kjcbbgse	86	16	although	although	IN
cord-005603-kjcbbgse	86	17	this	this	DT
cord-005603-kjcbbgse	86	18	proportion	proportion	NN
cord-005603-kjcbbgse	86	19	increased	increase	VBD
cord-005603-kjcbbgse	86	20	from	from	IN
cord-005603-kjcbbgse	86	21	42	42	CD
cord-005603-kjcbbgse	86	22	%	%	NN
cord-005603-kjcbbgse	86	23	when	when	WRB
cord-005603-kjcbbgse	86	24	patients	patient	NNS
cord-005603-kjcbbgse	86	25	only	only	RB
cord-005603-kjcbbgse	86	26	met	meet	VBD
cord-005603-kjcbbgse	86	27	criteria	criterion	NNS
cord-005603-kjcbbgse	86	28	for	for	IN
cord-005603-kjcbbgse	86	29	SIRS	SIRS	NNP
cord-005603-kjcbbgse	86	30	,	,	,
cord-005603-kjcbbgse	86	31	to	to	IN
cord-005603-kjcbbgse	86	32	57	57	CD
cord-005603-kjcbbgse	86	33	%	%	NN
cord-005603-kjcbbgse	86	34	in	in	IN
cord-005603-kjcbbgse	86	35	patients	patient	NNS
cord-005603-kjcbbgse	86	36	presenting	present	VBG
cord-005603-kjcbbgse	86	37	with	with	IN
cord-005603-kjcbbgse	86	38	shock	shock	NN
cord-005603-kjcbbgse	86	39	.	.	.
cord-005603-kjcbbgse	87	1	Importantly	importantly	RB
cord-005603-kjcbbgse	87	2	,	,	,
cord-005603-kjcbbgse	87	3	this	this	DT
cord-005603-kjcbbgse	87	4	study	study	NN
cord-005603-kjcbbgse	87	5	confirmed	confirm	VBD
cord-005603-kjcbbgse	87	6	the	the	DT
cord-005603-kjcbbgse	87	7	expected	expect	VBN
cord-005603-kjcbbgse	87	8	natural	natural	JJ
cord-005603-kjcbbgse	87	9	progression	progression	NN
cord-005603-kjcbbgse	87	10	between	between	IN
cord-005603-kjcbbgse	87	11	the	the	DT
cord-005603-kjcbbgse	87	12	different	different	JJ
cord-005603-kjcbbgse	87	13	stages	stage	NNS
cord-005603-kjcbbgse	87	14	of	of	IN
cord-005603-kjcbbgse	87	15	septic	septic	JJ
cord-005603-kjcbbgse	87	16	syndromes	syndrome	NNS
cord-005603-kjcbbgse	87	17	:	:	:
cord-005603-kjcbbgse	87	18	32	32	CD
cord-005603-kjcbbgse	87	19	%	%	NN
cord-005603-kjcbbgse	87	20	and	and	CC
cord-005603-kjcbbgse	87	21	36	36	CD
cord-005603-kjcbbgse	87	22	%	%	NN
cord-005603-kjcbbgse	87	23	of	of	IN
cord-005603-kjcbbgse	87	24	patients	patient	NNS
cord-005603-kjcbbgse	87	25	having	have	VBG
cord-005603-kjcbbgse	87	26	2	2	CD
cord-005603-kjcbbgse	87	27	or	or	CC
cord-005603-kjcbbgse	87	28	3	3	CD
cord-005603-kjcbbgse	87	29	SIRS	SIRS	NNP
cord-005603-kjcbbgse	87	30	criteria	criterion	NNS
cord-005603-kjcbbgse	87	31	,	,	,
cord-005603-kjcbbgse	87	32	respectively	respectively	RB
cord-005603-kjcbbgse	87	33	developed	develop	VBD
cord-005603-kjcbbgse	87	34	culture	culture	NN
cord-005603-kjcbbgse	87	35	-	-	HYPH
cord-005603-kjcbbgse	87	36	proven	prove	VBN
cord-005603-kjcbbgse	87	37	sepsis	sepsis	NN
cord-005603-kjcbbgse	87	38	by	by	IN
cord-005603-kjcbbgse	87	39	day	day	NN
cord-005603-kjcbbgse	87	40	14	14	CD
cord-005603-kjcbbgse	87	41	,	,	,
cord-005603-kjcbbgse	87	42	and	and	CC
cord-005603-kjcbbgse	87	43	45	45	CD
cord-005603-kjcbbgse	87	44	%	%	NN
cord-005603-kjcbbgse	87	45	of	of	IN
cord-005603-kjcbbgse	87	46	those	those	DT
cord-005603-kjcbbgse	87	47	with	with	IN
cord-005603-kjcbbgse	87	48	4	4	CD
cord-005603-kjcbbgse	87	49	criteria	criterion	NNS
cord-005603-kjcbbgse	87	50	subsequently	subsequently	RB
cord-005603-kjcbbgse	87	51	developed	develop	VBD
cord-005603-kjcbbgse	87	52	sepsis	sepsis	NN
cord-005603-kjcbbgse	87	53	,	,	,
cord-005603-kjcbbgse	87	54	while	while	IN
cord-005603-kjcbbgse	87	55	64	64	CD
cord-005603-kjcbbgse	87	56	%	%	NN
cord-005603-kjcbbgse	87	57	of	of	IN
cord-005603-kjcbbgse	87	58	those	those	DT
cord-005603-kjcbbgse	87	59	with	with	IN
cord-005603-kjcbbgse	87	60	sepsis	sepsis	NN
cord-005603-kjcbbgse	87	61	developed	develop	VBD
cord-005603-kjcbbgse	87	62	severe	severe	JJ
cord-005603-kjcbbgse	87	63	sepsis	sepsis	NN
cord-005603-kjcbbgse	87	64	,	,	,
cord-005603-kjcbbgse	87	65	a	a	DT
cord-005603-kjcbbgse	87	66	median	median	NN
cord-005603-kjcbbgse	87	67	of	of	IN
cord-005603-kjcbbgse	87	68	only	only	RB
cord-005603-kjcbbgse	87	69	1	1	CD
cord-005603-kjcbbgse	87	70	day	day	NN
cord-005603-kjcbbgse	87	71	after	after	IN
cord-005603-kjcbbgse	87	72	sepsis	sepsis	NN
cord-005603-kjcbbgse	87	73	;	;	:
cord-005603-kjcbbgse	87	74	conversely	conversely	RB
cord-005603-kjcbbgse	87	75	,	,	,
cord-005603-kjcbbgse	87	76	only	only	RB
cord-005603-kjcbbgse	87	77	23	23	CD
cord-005603-kjcbbgse	87	78	%	%	NN
cord-005603-kjcbbgse	87	79	of	of	IN
cord-005603-kjcbbgse	87	80	patients	patient	NNS
cord-005603-kjcbbgse	87	81	presenting	present	VBG
cord-005603-kjcbbgse	87	82	with	with	IN
cord-005603-kjcbbgse	87	83	severe	severe	JJ
cord-005603-kjcbbgse	87	84	sepsis	sepsis	NN
cord-005603-kjcbbgse	87	85	developed	develop	VBD
cord-005603-kjcbbgse	87	86	septic	septic	JJ
cord-005603-kjcbbgse	87	87	shock	shock	NN
cord-005603-kjcbbgse	87	88	,	,	,
cord-005603-kjcbbgse	87	89	and	and	CC
cord-005603-kjcbbgse	87	90	this	this	DT
cord-005603-kjcbbgse	87	91	occurrence	occurrence	NN
cord-005603-kjcbbgse	87	92	was	be	VBD
cord-005603-kjcbbgse	87	93	delayed	delay	VBN
cord-005603-kjcbbgse	87	94	by	by	IN
cord-005603-kjcbbgse	87	95	a	a	DT
cord-005603-kjcbbgse	87	96	median	median	NN
cord-005603-kjcbbgse	87	97	of	of	IN
cord-005603-kjcbbgse	87	98	28	28	CD
cord-005603-kjcbbgse	87	99	days	day	NNS
cord-005603-kjcbbgse	87	100	after	after	IN
cord-005603-kjcbbgse	87	101	severe	severe	JJ
cord-005603-kjcbbgse	87	102	sepsis	sepsis	NN
cord-005603-kjcbbgse	87	103	[	[	-LRB-
cord-005603-kjcbbgse	87	104	6	6	CD
cord-005603-kjcbbgse	87	105	,	,	,
cord-005603-kjcbbgse	87	106	7	7	CD
cord-005603-kjcbbgse	87	107	]	]	-RRB-
cord-005603-kjcbbgse	87	108	.	.	.
cord-005603-kjcbbgse	88	1	The	the	DT
cord-005603-kjcbbgse	88	2	authors	author	NNS
cord-005603-kjcbbgse	88	3	also	also	RB
cord-005603-kjcbbgse	88	4	noted	note	VBD
cord-005603-kjcbbgse	88	5	an	an	DT
cord-005603-kjcbbgse	88	6	increasing	increase	VBG
cord-005603-kjcbbgse	88	7	prevalence	prevalence	NN
cord-005603-kjcbbgse	88	8	of	of	IN
cord-005603-kjcbbgse	88	9	eventual	eventual	JJ
cord-005603-kjcbbgse	88	10	organ	organ	NN
cord-005603-kjcbbgse	88	11	dysfunctions	dysfunction	NNS
cord-005603-kjcbbgse	88	12	(	(	-LRB-
cord-005603-kjcbbgse	88	13	respiratory	respiratory	JJ
cord-005603-kjcbbgse	88	14	,	,	,
cord-005603-kjcbbgse	88	15	renal	renal	JJ
cord-005603-kjcbbgse	88	16	,	,	,
cord-005603-kjcbbgse	88	17	disseminated	disseminate	VBN
cord-005603-kjcbbgse	88	18	intravascular	intravascular	JJ
cord-005603-kjcbbgse	88	19	coagulation	coagulation	NN
cord-005603-kjcbbgse	88	20	and	and	CC
cord-005603-kjcbbgse	88	21	shock	shock	NN
cord-005603-kjcbbgse	88	22	)	)	-RRB-
cord-005603-kjcbbgse	88	23	with	with	IN
cord-005603-kjcbbgse	88	24	increasing	increase	VBG
cord-005603-kjcbbgse	88	25	number	number	NN
cord-005603-kjcbbgse	88	26	of	of	IN
cord-005603-kjcbbgse	88	27	SIRS	SIRS	NNP
cord-005603-kjcbbgse	88	28	criteria	criterion	NNS
cord-005603-kjcbbgse	88	29	.	.	.
cord-005603-kjcbbgse	89	1	Of	of	IN
cord-005603-kjcbbgse	89	2	note	note	NN
cord-005603-kjcbbgse	89	3	,	,	,
cord-005603-kjcbbgse	89	4	27	27	CD
cord-005603-kjcbbgse	89	5	%	%	NN
cord-005603-kjcbbgse	89	6	of	of	IN
cord-005603-kjcbbgse	89	7	patients	patient	NNS
cord-005603-kjcbbgse	89	8	meeting	meet	VBG
cord-005603-kjcbbgse	89	9	four	four	CD
cord-005603-kjcbbgse	89	10	SIRS	SIRS	NNP
cord-005603-kjcbbgse	89	11	criteria	criterion	NNS
cord-005603-kjcbbgse	89	12	developed	develop	VBD
cord-005603-kjcbbgse	89	13	shock	shock	NN
cord-005603-kjcbbgse	89	14	at	at	IN
cord-005603-kjcbbgse	89	15	some	some	DT
cord-005603-kjcbbgse	89	16	point	point	NN
cord-005603-kjcbbgse	89	17	in	in	IN
cord-005603-kjcbbgse	89	18	time	time	NN
cord-005603-kjcbbgse	89	19	.	.	.
cord-005603-kjcbbgse	90	1	Although	although	IN
cord-005603-kjcbbgse	90	2	there	there	EX
cord-005603-kjcbbgse	90	3	were	be	VBD
cord-005603-kjcbbgse	90	4	some	some	DT
cord-005603-kjcbbgse	90	5	minor	minor	JJ
cord-005603-kjcbbgse	90	6	differences	difference	NNS
cord-005603-kjcbbgse	90	7	in	in	IN
cord-005603-kjcbbgse	90	8	risk	risk	NN
cord-005603-kjcbbgse	90	9	of	of	IN
cord-005603-kjcbbgse	90	10	organ	organ	NN
cord-005603-kjcbbgse	90	11	failures	failure	NNS
cord-005603-kjcbbgse	90	12	depending	depend	VBG
cord-005603-kjcbbgse	90	13	on	on	IN
cord-005603-kjcbbgse	90	14	the	the	DT
cord-005603-kjcbbgse	90	15	stage	stage	NN
cord-005603-kjcbbgse	90	16	examined	examine	VBN
cord-005603-kjcbbgse	90	17	,	,	,
cord-005603-kjcbbgse	90	18	the	the	DT
cord-005603-kjcbbgse	90	19	overall	overall	JJ
cord-005603-kjcbbgse	90	20	rate	rate	NN
cord-005603-kjcbbgse	90	21	of	of	IN
cord-005603-kjcbbgse	90	22	organ	organ	NN
cord-005603-kjcbbgse	90	23	failures	failure	NNS
cord-005603-kjcbbgse	90	24	was	be	VBD
cord-005603-kjcbbgse	90	25	similar	similar	JJ
cord-005603-kjcbbgse	90	26	within	within	IN
cord-005603-kjcbbgse	90	27	each	each	DT
cord-005603-kjcbbgse	90	28	stage	stage	NN
cord-005603-kjcbbgse	90	29	(	(	-LRB-
cord-005603-kjcbbgse	90	30	as	as	RB
cord-005603-kjcbbgse	90	31	well	well	RB
cord-005603-kjcbbgse	90	32	as	as	IN
cord-005603-kjcbbgse	90	33	mortality	mortality	NN
cord-005603-kjcbbgse	90	34	)	)	-RRB-
cord-005603-kjcbbgse	90	35	whether	whether	IN
cord-005603-kjcbbgse	90	36	infection	infection	NN
cord-005603-kjcbbgse	90	37	was	be	VBD
cord-005603-kjcbbgse	90	38	confirmed	confirm	VBN
cord-005603-kjcbbgse	90	39	or	or	CC
cord-005603-kjcbbgse	90	40	not	not	RB
cord-005603-kjcbbgse	90	41	,	,	,
cord-005603-kjcbbgse	90	42	to	to	IN
cord-005603-kjcbbgse	90	43	the	the	DT
cord-005603-kjcbbgse	90	44	notable	notable	JJ
cord-005603-kjcbbgse	90	45	exception	exception	NN
cord-005603-kjcbbgse	90	46	of	of	IN
cord-005603-kjcbbgse	90	47	acute	acute	JJ
cord-005603-kjcbbgse	90	48	renal	renal	JJ
cord-005603-kjcbbgse	90	49	failure	failure	NN
cord-005603-kjcbbgse	90	50	,	,	,
cord-005603-kjcbbgse	90	51	which	which	WDT
cord-005603-kjcbbgse	90	52	was	be	VBD
cord-005603-kjcbbgse	90	53	more	more	RBR
cord-005603-kjcbbgse	90	54	frequent	frequent	JJ
cord-005603-kjcbbgse	90	55	at	at	IN
cord-005603-kjcbbgse	90	56	all	all	DT
cord-005603-kjcbbgse	90	57	stages	stage	NNS
cord-005603-kjcbbgse	90	58	in	in	IN
cord-005603-kjcbbgse	90	59	the	the	DT
cord-005603-kjcbbgse	90	60	presence	presence	NN
cord-005603-kjcbbgse	90	61	of	of	IN
cord-005603-kjcbbgse	90	62	confirmed	confirm	VBN
cord-005603-kjcbbgse	90	63	infection	infection	NN
cord-005603-kjcbbgse	90	64	.	.	.
cord-005603-kjcbbgse	91	1	Several	several	JJ
cord-005603-kjcbbgse	91	2	conclusions	conclusion	NNS
cord-005603-kjcbbgse	91	3	can	can	MD
cord-005603-kjcbbgse	91	4	be	be	VB
cord-005603-kjcbbgse	91	5	drawn	draw	VBN
cord-005603-kjcbbgse	91	6	from	from	IN
cord-005603-kjcbbgse	91	7	this	this	DT
cord-005603-kjcbbgse	91	8	study	study	NN
cord-005603-kjcbbgse	91	9	:	:	:
cord-005603-kjcbbgse	91	10	1	1	CD
cord-005603-kjcbbgse	91	11	.	.	.
cord-005603-kjcbbgse	92	1	The	the	DT
cord-005603-kjcbbgse	92	2	incidence	incidence	NN
cord-005603-kjcbbgse	92	3	of	of	IN
cord-005603-kjcbbgse	92	4	SIRS	SIRS	NNP
cord-005603-kjcbbgse	92	5	is	be	VBZ
cord-005603-kjcbbgse	92	6	very	very	RB
cord-005603-kjcbbgse	92	7	high	high	JJ
cord-005603-kjcbbgse	92	8	in	in	IN
cord-005603-kjcbbgse	92	9	ICU	ICU	NNP
cord-005603-kjcbbgse	92	10	patients	patient	NNS
cord-005603-kjcbbgse	92	11	,	,	,
cord-005603-kjcbbgse	92	12	and	and	CC
cord-005603-kjcbbgse	92	13	its	-PRON-	PRP$
cord-005603-kjcbbgse	92	14	recognition	recognition	NN
cord-005603-kjcbbgse	92	15	can	can	MD
cord-005603-kjcbbgse	92	16	not	not	RB
cord-005603-kjcbbgse	92	17	help	help	VB
cord-005603-kjcbbgse	92	18	in	in	IN
cord-005603-kjcbbgse	92	19	accurately	accurately	RB
cord-005603-kjcbbgse	92	20	identifying	identify	VBG
cord-005603-kjcbbgse	92	21	patients	patient	NNS
cord-005603-kjcbbgse	92	22	who	who	WP
cord-005603-kjcbbgse	92	23	will	will	MD
cord-005603-kjcbbgse	92	24	prove	prove	VB
cord-005603-kjcbbgse	92	25	to	to	TO
cord-005603-kjcbbgse	92	26	be	be	VB
cord-005603-kjcbbgse	92	27	infected	infect	VBN
cord-005603-kjcbbgse	92	28	or	or	CC
cord-005603-kjcbbgse	92	29	those	those	DT
cord-005603-kjcbbgse	92	30	at	at	IN
cord-005603-kjcbbgse	92	31	higher	high	JJR
cord-005603-kjcbbgse	92	32	risk	risk	NN
cord-005603-kjcbbgse	92	33	of	of	IN
cord-005603-kjcbbgse	92	34	the	the	DT
cord-005603-kjcbbgse	92	35	more	more	RBR
cord-005603-kjcbbgse	92	36	severe	severe	JJ
cord-005603-kjcbbgse	92	37	stages	stage	NNS
cord-005603-kjcbbgse	92	38	.	.	.
cord-005603-kjcbbgse	93	1	This	this	DT
cord-005603-kjcbbgse	93	2	is	be	VBZ
cord-005603-kjcbbgse	93	3	confirmed	confirm	VBN
cord-005603-kjcbbgse	93	4	by	by	IN
cord-005603-kjcbbgse	93	5	the	the	DT
cord-005603-kjcbbgse	93	6	fact	fact	NN
cord-005603-kjcbbgse	93	7	that	that	IN
cord-005603-kjcbbgse	93	8	only	only	RB
cord-005603-kjcbbgse	93	9	about	about	RB
cord-005603-kjcbbgse	93	10	one	one	CD
cord-005603-kjcbbgse	93	11	-	-	HYPH
cord-005603-kjcbbgse	93	12	third	third	NN
cord-005603-kjcbbgse	93	13	to	to	IN
cord-005603-kjcbbgse	93	14	onehalf	onehalf	NN
cord-005603-kjcbbgse	93	15	of	of	IN
cord-005603-kjcbbgse	93	16	patients	patient	NNS
cord-005603-kjcbbgse	93	17	meeting	meet	VBG
cord-005603-kjcbbgse	93	18	SIRS	SIRS	NNP
cord-005603-kjcbbgse	93	19	criteria	criterion	NNS
cord-005603-kjcbbgse	93	20	were	be	VBD
cord-005603-kjcbbgse	93	21	subsequently	subsequently	RB
cord-005603-kjcbbgse	93	22	proven	prove	VBN
cord-005603-kjcbbgse	93	23	to	to	TO
cord-005603-kjcbbgse	93	24	have	have	VB
cord-005603-kjcbbgse	93	25	confirmed	confirm	VBN
cord-005603-kjcbbgse	93	26	(	(	-LRB-
cord-005603-kjcbbgse	93	27	i.	i.	NNP
cord-005603-kjcbbgse	93	28	e.	e.	NNP
cord-005603-kjcbbgse	93	29	,	,	,
cord-005603-kjcbbgse	93	30	microbiologically	microbiologically	NNP
cord-005603-kjcbbgse	93	31	proven	prove	VBN
cord-005603-kjcbbgse	93	32	)	)	-RRB-
cord-005603-kjcbbgse	93	33	sepsis	sepsis	NN
cord-005603-kjcbbgse	93	34	;	;	:
cord-005603-kjcbbgse	93	35	the	the	DT
cord-005603-kjcbbgse	93	36	prevalence	prevalence	NN
cord-005603-kjcbbgse	93	37	of	of	IN
cord-005603-kjcbbgse	93	38	infection	infection	NN
cord-005603-kjcbbgse	93	39	,	,	,
cord-005603-kjcbbgse	93	40	however	however	RB
cord-005603-kjcbbgse	93	41	,	,	,
cord-005603-kjcbbgse	93	42	increases	increase	VBZ
cord-005603-kjcbbgse	93	43	with	with	IN
cord-005603-kjcbbgse	93	44	the	the	DT
cord-005603-kjcbbgse	93	45	number	number	NN
cord-005603-kjcbbgse	93	46	of	of	IN
cord-005603-kjcbbgse	93	47	SIRS	SIRS	NNP
cord-005603-kjcbbgse	93	48	criteria	criterion	NNS
cord-005603-kjcbbgse	93	49	met	meet	VBD
cord-005603-kjcbbgse	93	50	.	.	.
cord-005603-kjcbbgse	94	1	However	however	RB
cord-005603-kjcbbgse	94	2	,	,	,
cord-005603-kjcbbgse	94	3	this	this	DT
cord-005603-kjcbbgse	94	4	conclusion	conclusion	NN
cord-005603-kjcbbgse	94	5	must	must	MD
cord-005603-kjcbbgse	94	6	be	be	VB
cord-005603-kjcbbgse	94	7	tempered	temper	VBN
cord-005603-kjcbbgse	94	8	by	by	IN
cord-005603-kjcbbgse	94	9	the	the	DT
cord-005603-kjcbbgse	94	10	fact	fact	NN
cord-005603-kjcbbgse	94	11	that	that	IN
cord-005603-kjcbbgse	94	12	many	many	JJ
cord-005603-kjcbbgse	94	13	patients	patient	NNS
cord-005603-kjcbbgse	94	14	with	with	IN
cord-005603-kjcbbgse	94	15	SIRS	SIRS	NNP
cord-005603-kjcbbgse	94	16	were	be	VBD
cord-005603-kjcbbgse	94	17	thought	think	VBN
cord-005603-kjcbbgse	94	18	to	to	TO
cord-005603-kjcbbgse	94	19	have	have	VB
cord-005603-kjcbbgse	94	20	infection	infection	NN
cord-005603-kjcbbgse	94	21	,	,	,
cord-005603-kjcbbgse	94	22	and	and	CC
cord-005603-kjcbbgse	94	23	were	be	VBD
cord-005603-kjcbbgse	94	24	thus	thus	RB
cord-005603-kjcbbgse	94	25	administered	administer	VBN
cord-005603-kjcbbgse	94	26	empirical	empirical	JJ
cord-005603-kjcbbgse	94	27	antimicrobial	antimicrobial	JJ
cord-005603-kjcbbgse	94	28	therapy	therapy	NN
cord-005603-kjcbbgse	94	29	,	,	,
cord-005603-kjcbbgse	94	30	which	which	WDT
cord-005603-kjcbbgse	94	31	likely	likely	RB
cord-005603-kjcbbgse	94	32	interfered	interfere	VBD
cord-005603-kjcbbgse	94	33	with	with	IN
cord-005603-kjcbbgse	94	34	the	the	DT
cord-005603-kjcbbgse	94	35	documentation	documentation	NN
cord-005603-kjcbbgse	94	36	of	of	IN
cord-005603-kjcbbgse	94	37	infection	infection	NN
cord-005603-kjcbbgse	94	38	;	;	:
cord-005603-kjcbbgse	94	39	the	the	DT
cord-005603-kjcbbgse	94	40	actual	actual	JJ
cord-005603-kjcbbgse	94	41	proportion	proportion	NN
cord-005603-kjcbbgse	94	42	of	of	IN
cord-005603-kjcbbgse	94	43	non	non	JJ
cord-005603-kjcbbgse	94	44	-	-	JJ
cord-005603-kjcbbgse	94	45	infectious	infectious	JJ
cord-005603-kjcbbgse	94	46	SIRS	sir	NNS
cord-005603-kjcbbgse	94	47	or	or	CC
cord-005603-kjcbbgse	94	48	ªsevere	ªsevere	NN
cord-005603-kjcbbgse	94	49	SIRSº	SIRSº	NNS
cord-005603-kjcbbgse	94	50	in	in	IN
cord-005603-kjcbbgse	94	51	this	this	DT
cord-005603-kjcbbgse	94	52	study	study	NN
cord-005603-kjcbbgse	94	53	is	be	VBZ
cord-005603-kjcbbgse	94	54	unknown	unknown	JJ
cord-005603-kjcbbgse	94	55	.	.	.
cord-005603-kjcbbgse	95	1	2	2	LS
cord-005603-kjcbbgse	95	2	.	.	.
cord-005603-kjcbbgse	96	1	There	there	EX
cord-005603-kjcbbgse	96	2	is	be	VBZ
cord-005603-kjcbbgse	96	3	indeed	indeed	RB
cord-005603-kjcbbgse	96	4	a	a	DT
cord-005603-kjcbbgse	96	5	continuum	continuum	NN
cord-005603-kjcbbgse	96	6	between	between	IN
cord-005603-kjcbbgse	96	7	the	the	DT
cord-005603-kjcbbgse	96	8	different	different	JJ
cord-005603-kjcbbgse	96	9	stages	stage	NNS
cord-005603-kjcbbgse	96	10	of	of	IN
cord-005603-kjcbbgse	96	11	the	the	DT
cord-005603-kjcbbgse	96	12	inflammatory	inflammatory	JJ
cord-005603-kjcbbgse	96	13	response	response	NN
cord-005603-kjcbbgse	96	14	from	from	IN
cord-005603-kjcbbgse	96	15	SIRS	SIRS	NNP
cord-005603-kjcbbgse	96	16	to	to	IN
cord-005603-kjcbbgse	96	17	sepsis	sepsis	NN
cord-005603-kjcbbgse	96	18	,	,	,
cord-005603-kjcbbgse	96	19	severe	severe	JJ
cord-005603-kjcbbgse	96	20	sepsis	sepsis	NN
cord-005603-kjcbbgse	96	21	and	and	CC
cord-005603-kjcbbgse	96	22	shock	shock	NN
cord-005603-kjcbbgse	96	23	.	.	.
cord-005603-kjcbbgse	97	1	However	however	RB
cord-005603-kjcbbgse	97	2	,	,	,
cord-005603-kjcbbgse	97	3	only	only	RB
cord-005603-kjcbbgse	97	4	about	about	RB
cord-005603-kjcbbgse	97	5	one	one	CD
cord-005603-kjcbbgse	97	6	-	-	HYPH
cord-005603-kjcbbgse	97	7	third	third	NN
cord-005603-kjcbbgse	97	8	of	of	IN
cord-005603-kjcbbgse	97	9	patients	patient	NNS
cord-005603-kjcbbgse	97	10	presenting	present	VBG
cord-005603-kjcbbgse	97	11	with	with	IN
cord-005603-kjcbbgse	97	12	SIRS	SIRS	NNP
cord-005603-kjcbbgse	97	13	have	have	VBP
cord-005603-kjcbbgse	97	14	confirmed	confirm	VBN
cord-005603-kjcbbgse	97	15	sepsis	sepsis	NN
cord-005603-kjcbbgse	97	16	and	and	CC
cord-005603-kjcbbgse	97	17	about	about	RB
cord-005603-kjcbbgse	97	18	one	one	CD
cord-005603-kjcbbgse	97	19	-	-	HYPH
cord-005603-kjcbbgse	97	20	fourth	fourth	NN
cord-005603-kjcbbgse	97	21	will	will	MD
cord-005603-kjcbbgse	97	22	evolve	evolve	VB
cord-005603-kjcbbgse	97	23	to	to	TO
cord-005603-kjcbbgse	97	24	severe	severe	JJ
cord-005603-kjcbbgse	97	25	sepsis	sepsis	NN
cord-005603-kjcbbgse	97	26	.	.	.
cord-005603-kjcbbgse	98	1	Conversely	conversely	RB
cord-005603-kjcbbgse	98	2	,	,	,
cord-005603-kjcbbgse	98	3	sepsis	sepsis	NN
cord-005603-kjcbbgse	98	4	(	(	-LRB-
cord-005603-kjcbbgse	98	5	microbiologically	microbiologically	RB
cord-005603-kjcbbgse	98	6	confirmed	confirm	VBD
cord-005603-kjcbbgse	98	7	)	)	-RRB-
cord-005603-kjcbbgse	98	8	appears	appear	VBZ
cord-005603-kjcbbgse	98	9	at	at	IN
cord-005603-kjcbbgse	98	10	high	high	JJ
cord-005603-kjcbbgse	98	11	risk	risk	NN
cord-005603-kjcbbgse	98	12	of	of	IN
cord-005603-kjcbbgse	98	13	evolving	evolve	VBG
cord-005603-kjcbbgse	98	14	rapidly	rapidly	RB
cord-005603-kjcbbgse	98	15	to	to	IN
cord-005603-kjcbbgse	98	16	severe	severe	JJ
cord-005603-kjcbbgse	98	17	sepsis	sepsis	NN
cord-005603-kjcbbgse	98	18	,	,	,
cord-005603-kjcbbgse	98	19	as	as	IN
cord-005603-kjcbbgse	98	20	shown	show	VBN
cord-005603-kjcbbgse	98	21	by	by	IN
cord-005603-kjcbbgse	98	22	the	the	DT
cord-005603-kjcbbgse	98	23	64	64	CD
cord-005603-kjcbbgse	98	24	%	%	NN
cord-005603-kjcbbgse	98	25	proportion	proportion	NN
cord-005603-kjcbbgse	98	26	of	of	IN
cord-005603-kjcbbgse	98	27	cases	case	NNS
cord-005603-kjcbbgse	98	28	subsequently	subsequently	RB
cord-005603-kjcbbgse	98	29	developing	develop	VBG
cord-005603-kjcbbgse	98	30	severe	severe	JJ
cord-005603-kjcbbgse	98	31	sepsis	sepsis	NN
cord-005603-kjcbbgse	98	32	,	,	,
cord-005603-kjcbbgse	98	33	of	of	IN
cord-005603-kjcbbgse	98	34	which	which	WDT
cord-005603-kjcbbgse	98	35	one	one	CD
cord-005603-kjcbbgse	98	36	-	-	HYPH
cord-005603-kjcbbgse	98	37	half	half	NN
cord-005603-kjcbbgse	98	38	will	will	MD
cord-005603-kjcbbgse	98	39	occur	occur	VB
cord-005603-kjcbbgse	98	40	within	within	IN
cord-005603-kjcbbgse	98	41	one	one	CD
cord-005603-kjcbbgse	98	42	day	day	NN
cord-005603-kjcbbgse	98	43	of	of	IN
cord-005603-kjcbbgse	98	44	sepsis	sepsis	NN
cord-005603-kjcbbgse	98	45	.	.	.
cord-005603-kjcbbgse	99	1	3	3	LS
cord-005603-kjcbbgse	99	2	.	.	.
cord-005603-kjcbbgse	100	1	Whether	whether	IN
cord-005603-kjcbbgse	100	2	infection	infection	NN
cord-005603-kjcbbgse	100	3	is	be	VBZ
cord-005603-kjcbbgse	100	4	confirmed	confirm	VBN
cord-005603-kjcbbgse	100	5	or	or	CC
cord-005603-kjcbbgse	100	6	not	not	RB
cord-005603-kjcbbgse	100	7	,	,	,
cord-005603-kjcbbgse	100	8	the	the	DT
cord-005603-kjcbbgse	100	9	outcomes	outcome	NNS
cord-005603-kjcbbgse	100	10	are	be	VBP
cord-005603-kjcbbgse	100	11	similar	similar	JJ
cord-005603-kjcbbgse	100	12	in	in	IN
cord-005603-kjcbbgse	100	13	terms	term	NNS
cord-005603-kjcbbgse	100	14	of	of	IN
cord-005603-kjcbbgse	100	15	organ	organ	NN
cord-005603-kjcbbgse	100	16	dysfunctions	dysfunction	NNS
cord-005603-kjcbbgse	100	17	and	and	CC
cord-005603-kjcbbgse	100	18	mortality	mortality	NN
cord-005603-kjcbbgse	100	19	,	,	,
cord-005603-kjcbbgse	100	20	within	within	IN
cord-005603-kjcbbgse	100	21	each	each	DT
cord-005603-kjcbbgse	100	22	corresponding	corresponding	JJ
cord-005603-kjcbbgse	100	23	stage	stage	NN
cord-005603-kjcbbgse	100	24	(	(	-LRB-
cord-005603-kjcbbgse	100	25	with	with	IN
cord-005603-kjcbbgse	100	26	the	the	DT
cord-005603-kjcbbgse	100	27	possible	possible	JJ
cord-005603-kjcbbgse	100	28	exception	exception	NN
cord-005603-kjcbbgse	100	29	of	of	IN
cord-005603-kjcbbgse	100	30	renal	renal	JJ
cord-005603-kjcbbgse	100	31	failure	failure	NN
cord-005603-kjcbbgse	100	32	)	)	-RRB-
cord-005603-kjcbbgse	100	33	.	.	.
cord-005603-kjcbbgse	101	1	In	in	IN
cord-005603-kjcbbgse	101	2	another	another	DT
cord-005603-kjcbbgse	101	3	large	large	JJ
cord-005603-kjcbbgse	101	4	study	study	NN
cord-005603-kjcbbgse	101	5	,	,	,
cord-005603-kjcbbgse	101	6	Sands	Sands	NNPS
cord-005603-kjcbbgse	101	7	[	[	-LRB-
cord-005603-kjcbbgse	101	8	10	10	CD
cord-005603-kjcbbgse	101	9	]	]	-RRB-
cord-005603-kjcbbgse	101	10	have	have	VBP
cord-005603-kjcbbgse	101	11	evaluated	evaluate	VBN
cord-005603-kjcbbgse	101	12	168	168	CD
cord-005603-kjcbbgse	101	13	patients	patient	NNS
cord-005603-kjcbbgse	101	14	with	with	IN
cord-005603-kjcbbgse	101	15	severe	severe	JJ
cord-005603-kjcbbgse	101	16	trauma	trauma	NN
cord-005603-kjcbbgse	101	17	during	during	IN
cord-005603-kjcbbgse	101	18	the	the	DT
cord-005603-kjcbbgse	101	19	first	first	JJ
cord-005603-kjcbbgse	101	20	48	48	CD
cord-005603-kjcbbgse	101	21	hours	hour	NNS
cord-005603-kjcbbgse	101	22	in	in	IN
cord-005603-kjcbbgse	101	23	the	the	DT
cord-005603-kjcbbgse	101	24	SICU	SICU	NNP
cord-005603-kjcbbgse	101	25	;	;	:
cord-005603-kjcbbgse	101	26	95	95	CD
cord-005603-kjcbbgse	101	27	(	(	-LRB-
cord-005603-kjcbbgse	101	28	56	56	CD
cord-005603-kjcbbgse	101	29	%	%	NN
cord-005603-kjcbbgse	101	30	)	)	-RRB-
cord-005603-kjcbbgse	101	31	had	have	VBD
cord-005603-kjcbbgse	101	32	SIRS	sir	NNS
cord-005603-kjcbbgse	101	33	.	.	.
cord-005603-kjcbbgse	102	1	When	when	WRB
cord-005603-kjcbbgse	102	2	stratifying	stratify	VBG
cord-005603-kjcbbgse	102	3	patients	patient	NNS
cord-005603-kjcbbgse	102	4	on	on	IN
cord-005603-kjcbbgse	102	5	the	the	DT
cord-005603-kjcbbgse	102	6	presence	presence	NN
cord-005603-kjcbbgse	102	7	of	of	IN
cord-005603-kjcbbgse	102	8	multiple	multiple	JJ
cord-005603-kjcbbgse	102	9	organ	organ	NN
cord-005603-kjcbbgse	102	10	dysfunction	dysfunction	NN
cord-005603-kjcbbgse	102	11	(	(	-LRB-
cord-005603-kjcbbgse	102	12	MODS	MODS	NNP
cord-005603-kjcbbgse	102	13	)	)	-RRB-
cord-005603-kjcbbgse	102	14	,	,	,
cord-005603-kjcbbgse	102	15	these	these	DT
cord-005603-kjcbbgse	102	16	authors	author	NNS
cord-005603-kjcbbgse	102	17	found	find	VBD
cord-005603-kjcbbgse	102	18	that	that	IN
cord-005603-kjcbbgse	102	19	the	the	DT
cord-005603-kjcbbgse	102	20	rate	rate	NN
cord-005603-kjcbbgse	102	21	of	of	IN
cord-005603-kjcbbgse	102	22	SIRS	SIRS	NNP
cord-005603-kjcbbgse	102	23	was	be	VBD
cord-005603-kjcbbgse	102	24	much	much	RB
cord-005603-kjcbbgse	102	25	higher	high	JJR
cord-005603-kjcbbgse	102	26	in	in	IN
cord-005603-kjcbbgse	102	27	patients	patient	NNS
cord-005603-kjcbbgse	102	28	with	with	IN
cord-005603-kjcbbgse	102	29	MODS	MODS	NNP
cord-005603-kjcbbgse	102	30	(	(	-LRB-
cord-005603-kjcbbgse	102	31	22/27	22/27	CD
cord-005603-kjcbbgse	102	32	,	,	,
cord-005603-kjcbbgse	102	33	81	81	CD
cord-005603-kjcbbgse	102	34	%	%	NN
cord-005603-kjcbbgse	102	35	)	)	-RRB-
cord-005603-kjcbbgse	102	36	than	than	IN
cord-005603-kjcbbgse	102	37	in	in	IN
cord-005603-kjcbbgse	102	38	patients	patient	NNS
cord-005603-kjcbbgse	102	39	without	without	IN
cord-005603-kjcbbgse	102	40	(	(	-LRB-
cord-005603-kjcbbgse	102	41	73/136	73/136	CD
cord-005603-kjcbbgse	102	42	,	,	,
cord-005603-kjcbbgse	102	43	54	54	CD
cord-005603-kjcbbgse	102	44	%	%	NN
cord-005603-kjcbbgse	102	45	)	)	-RRB-
cord-005603-kjcbbgse	102	46	.	.	.
cord-005603-kjcbbgse	103	1	The	the	DT
cord-005603-kjcbbgse	103	2	occurrence	occurrence	NN
cord-005603-kjcbbgse	103	3	of	of	IN
cord-005603-kjcbbgse	103	4	MODS	mods	NN
cord-005603-kjcbbgse	103	5	appeared	appear	VBD
cord-005603-kjcbbgse	103	6	related	relate	VBN
cord-005603-kjcbbgse	103	7	to	to	IN
cord-005603-kjcbbgse	103	8	the	the	DT
cord-005603-kjcbbgse	103	9	severity	severity	NN
cord-005603-kjcbbgse	103	10	of	of	IN
cord-005603-kjcbbgse	103	11	injury	injury	NN
cord-005603-kjcbbgse	103	12	,	,	,
cord-005603-kjcbbgse	103	13	the	the	DT
cord-005603-kjcbbgse	103	14	volume	volume	NN
cord-005603-kjcbbgse	103	15	of	of	IN
cord-005603-kjcbbgse	103	16	blood	blood	NN
cord-005603-kjcbbgse	103	17	and	and	CC
cord-005603-kjcbbgse	103	18	fluid	fluid	NN
cord-005603-kjcbbgse	103	19	replacement	replacement	NN
cord-005603-kjcbbgse	103	20	,	,	,
cord-005603-kjcbbgse	103	21	but	but	CC
cord-005603-kjcbbgse	103	22	not	not	RB
cord-005603-kjcbbgse	103	23	to	to	IN
cord-005603-kjcbbgse	103	24	the	the	DT
cord-005603-kjcbbgse	103	25	presence	presence	NN
cord-005603-kjcbbgse	103	26	of	of	IN
cord-005603-kjcbbgse	103	27	infection	infection	NN
cord-005603-kjcbbgse	103	28	:	:	:
cord-005603-kjcbbgse	103	29	infection	infection	NN
cord-005603-kjcbbgse	103	30	rates	rate	NNS
cord-005603-kjcbbgse	103	31	were	be	VBD
cord-005603-kjcbbgse	103	32	9	9	CD
cord-005603-kjcbbgse	103	33	%	%	NN
cord-005603-kjcbbgse	103	34	and	and	CC
cord-005603-kjcbbgse	103	35	4	4	CD
cord-005603-kjcbbgse	103	36	%	%	NN
cord-005603-kjcbbgse	103	37	,	,	,
cord-005603-kjcbbgse	103	38	respectively	respectively	RB
cord-005603-kjcbbgse	103	39	,	,	,
cord-005603-kjcbbgse	103	40	in	in	IN
cord-005603-kjcbbgse	103	41	patients	patient	NNS
cord-005603-kjcbbgse	103	42	with	with	IN
cord-005603-kjcbbgse	103	43	and	and	CC
cord-005603-kjcbbgse	103	44	without	without	IN
cord-005603-kjcbbgse	103	45	MODS	mod	NNS
cord-005603-kjcbbgse	103	46	.	.	.
cord-005603-kjcbbgse	104	1	As	as	IN
cord-005603-kjcbbgse	104	2	expected	expect	VBN
cord-005603-kjcbbgse	104	3	in	in	IN
cord-005603-kjcbbgse	104	4	this	this	DT
cord-005603-kjcbbgse	104	5	particular	particular	JJ
cord-005603-kjcbbgse	104	6	population	population	NN
cord-005603-kjcbbgse	104	7	,	,	,
cord-005603-kjcbbgse	104	8	SIRS	SIRS	NNP
cord-005603-kjcbbgse	104	9	appeared	appear	VBD
cord-005603-kjcbbgse	104	10	as	as	IN
cord-005603-kjcbbgse	104	11	an	an	DT
cord-005603-kjcbbgse	104	12	extremely	extremely	RB
cord-005603-kjcbbgse	104	13	frequent	frequent	JJ
cord-005603-kjcbbgse	104	14	and	and	CC
cord-005603-kjcbbgse	104	15	non	non	JJ
cord-005603-kjcbbgse	104	16	-	-	JJ
cord-005603-kjcbbgse	104	17	specific	specific	JJ
cord-005603-kjcbbgse	104	18	finding	finding	NN
cord-005603-kjcbbgse	104	19	,	,	,
cord-005603-kjcbbgse	104	20	irrespective	irrespective	RB
cord-005603-kjcbbgse	104	21	of	of	IN
cord-005603-kjcbbgse	104	22	the	the	DT
cord-005603-kjcbbgse	104	23	presence	presence	NN
cord-005603-kjcbbgse	104	24	of	of	IN
cord-005603-kjcbbgse	104	25	infection	infection	NN
cord-005603-kjcbbgse	104	26	.	.	.
cord-005603-kjcbbgse	105	1	Likewise	likewise	RB
cord-005603-kjcbbgse	105	2	,	,	,
cord-005603-kjcbbgse	105	3	Muckart	Muckart	NNP
cord-005603-kjcbbgse	105	4	and	and	CC
cord-005603-kjcbbgse	105	5	Bhangwanjee	Bhangwanjee	NNP
cord-005603-kjcbbgse	105	6	assessed	assess	VBD
cord-005603-kjcbbgse	105	7	the	the	DT
cord-005603-kjcbbgse	105	8	incidence	incidence	NN
cord-005603-kjcbbgse	105	9	of	of	IN
cord-005603-kjcbbgse	105	10	the	the	DT
cord-005603-kjcbbgse	105	11	septic	septic	JJ
cord-005603-kjcbbgse	105	12	syndromes	syndrome	NNS
cord-005603-kjcbbgse	105	13	in	in	IN
cord-005603-kjcbbgse	105	14	penetrating	penetrating	JJ
cord-005603-kjcbbgse	105	15	or	or	CC
cord-005603-kjcbbgse	105	16	blunt	blunt	JJ
cord-005603-kjcbbgse	105	17	trauma	trauma	NN
cord-005603-kjcbbgse	105	18	[	[	-LRB-
cord-005603-kjcbbgse	105	19	11	11	CD
cord-005603-kjcbbgse	105	20	]	]	-RRB-
cord-005603-kjcbbgse	105	21	.	.	.
cord-005603-kjcbbgse	106	1	Of	of	IN
cord-005603-kjcbbgse	106	2	450	450	CD
cord-005603-kjcbbgse	106	3	patients	patient	NNS
cord-005603-kjcbbgse	106	4	followed	follow	VBN
cord-005603-kjcbbgse	106	5	-	-	HYPH
cord-005603-kjcbbgse	106	6	up	up	NN
cord-005603-kjcbbgse	106	7	,	,	,
cord-005603-kjcbbgse	106	8	399	399	CD
cord-005603-kjcbbgse	106	9	(	(	-LRB-
cord-005603-kjcbbgse	106	10	88	88	CD
cord-005603-kjcbbgse	106	11	%	%	NN
cord-005603-kjcbbgse	106	12	)	)	-RRB-
cord-005603-kjcbbgse	106	13	fulfilled	fulfil	VBD
cord-005603-kjcbbgse	106	14	SIRS	SIRS	NNP
cord-005603-kjcbbgse	106	15	criteria	criterion	NNS
cord-005603-kjcbbgse	106	16	:	:	:
cord-005603-kjcbbgse	106	17	22	22	CD
cord-005603-kjcbbgse	106	18	%	%	NN
cord-005603-kjcbbgse	106	19	had	have	VBD
cord-005603-kjcbbgse	106	20	SIRS	SIRS	NNP
cord-005603-kjcbbgse	106	21	only	only	RB
cord-005603-kjcbbgse	106	22	and	and	CC
cord-005603-kjcbbgse	106	23	14	14	CD
cord-005603-kjcbbgse	106	24	%	%	NN
cord-005603-kjcbbgse	106	25	sepsis	sepsis	NN
cord-005603-kjcbbgse	106	26	;	;	:
cord-005603-kjcbbgse	106	27	14	14	CD
cord-005603-kjcbbgse	106	28	%	%	NN
cord-005603-kjcbbgse	106	29	had	have	VBD
cord-005603-kjcbbgse	106	30	severe	severe	JJ
cord-005603-kjcbbgse	106	31	sepsis	sepsis	NN
cord-005603-kjcbbgse	106	32	and	and	CC
cord-005603-kjcbbgse	106	33	8	8	CD
cord-005603-kjcbbgse	106	34	%	%	NN
cord-005603-kjcbbgse	106	35	severe	severe	JJ
cord-005603-kjcbbgse	106	36	SIRS	SIRS	NNP
cord-005603-kjcbbgse	106	37	;	;	:
cord-005603-kjcbbgse	106	38	and	and	CC
cord-005603-kjcbbgse	106	39	20	20	CD
cord-005603-kjcbbgse	106	40	%	%	NN
cord-005603-kjcbbgse	106	41	had	have	VBD
cord-005603-kjcbbgse	106	42	septic	septic	JJ
cord-005603-kjcbbgse	106	43	shock	shock	NN
cord-005603-kjcbbgse	106	44	and	and	CC
cord-005603-kjcbbgse	106	45	9	9	CD
cord-005603-kjcbbgse	106	46	%	%	NN
cord-005603-kjcbbgse	106	47	non	non	JJ
cord-005603-kjcbbgse	106	48	-	-	JJ
cord-005603-kjcbbgse	106	49	documented	documented	JJ
cord-005603-kjcbbgse	106	50	septic	septic	JJ
cord-005603-kjcbbgse	106	51	shock	shock	NN
cord-005603-kjcbbgse	106	52	.	.	.
cord-005603-kjcbbgse	107	1	Documentation	documentation	NN
cord-005603-kjcbbgse	107	2	of	of	IN
cord-005603-kjcbbgse	107	3	infection	infection	NN
cord-005603-kjcbbgse	107	4	was	be	VBD
cord-005603-kjcbbgse	107	5	more	more	RBR
cord-005603-kjcbbgse	107	6	frequent	frequent	JJ
cord-005603-kjcbbgse	107	7	with	with	IN
cord-005603-kjcbbgse	107	8	penetrating	penetrating	JJ
cord-005603-kjcbbgse	107	9	trauma	trauma	NN
cord-005603-kjcbbgse	107	10	.	.	.
cord-005603-kjcbbgse	108	1	In	in	IN
cord-005603-kjcbbgse	108	2	the	the	DT
cord-005603-kjcbbgse	108	3	Italian	italian	JJ
cord-005603-kjcbbgse	108	4	multicenter	multicenter	JJ
cord-005603-kjcbbgse	108	5	study	study	NN
cord-005603-kjcbbgse	108	6	conducted	conduct	VBN
cord-005603-kjcbbgse	108	7	in	in	IN
cord-005603-kjcbbgse	108	8	1993±1994	1993±1994	CD
cord-005603-kjcbbgse	108	9	in	in	IN
cord-005603-kjcbbgse	108	10	99	99	CD
cord-005603-kjcbbgse	108	11	ICUs	icu	NNS
cord-005603-kjcbbgse	108	12	[	[	-LRB-
cord-005603-kjcbbgse	108	13	12	12	CD
cord-005603-kjcbbgse	108	14	]	]	-RRB-
cord-005603-kjcbbgse	108	15	,	,	,
cord-005603-kjcbbgse	108	16	52	52	CD
cord-005603-kjcbbgse	108	17	%	%	NN
cord-005603-kjcbbgse	108	18	of	of	IN
cord-005603-kjcbbgse	108	19	1101	1101	CD
cord-005603-kjcbbgse	108	20	patients	patient	NNS
cord-005603-kjcbbgse	108	21	had	have	VBD
cord-005603-kjcbbgse	108	22	SIRS	SIRS	NNP
cord-005603-kjcbbgse	108	23	on	on	IN
cord-005603-kjcbbgse	108	24	admission	admission	NN
cord-005603-kjcbbgse	108	25	;	;	:
cord-005603-kjcbbgse	108	26	at	at	IN
cord-005603-kjcbbgse	108	27	any	any	DT
cord-005603-kjcbbgse	108	28	time	time	NN
cord-005603-kjcbbgse	108	29	during	during	IN
cord-005603-kjcbbgse	108	30	the	the	DT
cord-005603-kjcbbgse	108	31	study	study	NN
cord-005603-kjcbbgse	108	32	,	,	,
cord-005603-kjcbbgse	108	33	SIRS	SIRS	NNP
cord-005603-kjcbbgse	108	34	only	only	RB
cord-005603-kjcbbgse	108	35	was	be	VBD
cord-005603-kjcbbgse	108	36	recorded	record	VBN
cord-005603-kjcbbgse	108	37	in	in	IN
cord-005603-kjcbbgse	108	38	58	58	CD
cord-005603-kjcbbgse	108	39	%	%	NN
cord-005603-kjcbbgse	108	40	of	of	IN
cord-005603-kjcbbgse	108	41	patients	patient	NNS
cord-005603-kjcbbgse	108	42	,	,	,
cord-005603-kjcbbgse	108	43	sepsis	sepsis	NN
cord-005603-kjcbbgse	108	44	in	in	IN
cord-005603-kjcbbgse	108	45	another	another	DT
cord-005603-kjcbbgse	108	46	16	16	CD
cord-005603-kjcbbgse	108	47	%	%	NN
cord-005603-kjcbbgse	108	48	,	,	,
cord-005603-kjcbbgse	108	49	severe	severe	JJ
cord-005603-kjcbbgse	108	50	sepsis	sepsis	NN
cord-005603-kjcbbgse	108	51	in	in	IN
cord-005603-kjcbbgse	108	52	5.5	5.5	CD
cord-005603-kjcbbgse	108	53	%	%	NN
cord-005603-kjcbbgse	108	54	,	,	,
cord-005603-kjcbbgse	108	55	and	and	CC
cord-005603-kjcbbgse	108	56	septic	septic	JJ
cord-005603-kjcbbgse	108	57	shock	shock	NN
cord-005603-kjcbbgse	108	58	in	in	IN
cord-005603-kjcbbgse	108	59	6	6	CD
cord-005603-kjcbbgse	108	60	%	%	NN
cord-005603-kjcbbgse	108	61	.	.	.
cord-005603-kjcbbgse	109	1	Overall	overall	RB
cord-005603-kjcbbgse	109	2	,	,	,
cord-005603-kjcbbgse	109	3	85	85	CD
cord-005603-kjcbbgse	109	4	%	%	NN
cord-005603-kjcbbgse	109	5	of	of	IN
cord-005603-kjcbbgse	109	6	patients	patient	NNS
cord-005603-kjcbbgse	109	7	had	have	VBD
cord-005603-kjcbbgse	109	8	one	one	CD
cord-005603-kjcbbgse	109	9	of	of	IN
cord-005603-kjcbbgse	109	10	the	the	DT
cord-005603-kjcbbgse	109	11	septic	septic	JJ
cord-005603-kjcbbgse	109	12	syndromes	syndrome	NNS
cord-005603-kjcbbgse	109	13	,	,	,
cord-005603-kjcbbgse	110	1	of	of	IN
cord-005603-kjcbbgse	110	2	which	which	WDT
cord-005603-kjcbbgse	110	3	more	more	JJR
cord-005603-kjcbbgse	110	4	than	than	IN
cord-005603-kjcbbgse	110	5	two	two	CD
cord-005603-kjcbbgse	110	6	-	-	HYPH
cord-005603-kjcbbgse	110	7	thirds	third	NNS
cord-005603-kjcbbgse	110	8	were	be	VBD
cord-005603-kjcbbgse	110	9	non	non	JJ
cord-005603-kjcbbgse	110	10	-	-	JJ
cord-005603-kjcbbgse	110	11	microbiologically	microbiologically	RB
cord-005603-kjcbbgse	110	12	documented	document	VBN
cord-005603-kjcbbgse	110	13	SIRS	SIRS	NNP
cord-005603-kjcbbgse	110	14	.	.	.
cord-005603-kjcbbgse	111	1	Similarly	similarly	RB
cord-005603-kjcbbgse	111	2	to	to	IN
cord-005603-kjcbbgse	111	3	the	the	DT
cord-005603-kjcbbgse	111	4	study	study	NN
cord-005603-kjcbbgse	111	5	from	from	IN
cord-005603-kjcbbgse	111	6	Iowa	Iowa	NNP
cord-005603-kjcbbgse	111	7	[	[	-LRB-
cord-005603-kjcbbgse	111	8	6	6	CD
cord-005603-kjcbbgse	111	9	]	]	-RRB-
cord-005603-kjcbbgse	111	10	the	the	DT
cord-005603-kjcbbgse	111	11	investigators	investigator	NNS
cord-005603-kjcbbgse	111	12	noted	note	VBD
cord-005603-kjcbbgse	111	13	that	that	IN
cord-005603-kjcbbgse	111	14	a	a	DT
cord-005603-kjcbbgse	111	15	substantial	substantial	JJ
cord-005603-kjcbbgse	111	16	proportion	proportion	NN
cord-005603-kjcbbgse	111	17	of	of	IN
cord-005603-kjcbbgse	111	18	patients	patient	NNS
cord-005603-kjcbbgse	111	19	evolved	evolve	VBN
cord-005603-kjcbbgse	111	20	from	from	IN
cord-005603-kjcbbgse	111	21	an	an	DT
cord-005603-kjcbbgse	111	22	earlier	early	JJR
cord-005603-kjcbbgse	111	23	stage	stage	NN
cord-005603-kjcbbgse	111	24	on	on	IN
cord-005603-kjcbbgse	111	25	admission	admission	NN
cord-005603-kjcbbgse	111	26	to	to	IN
cord-005603-kjcbbgse	111	27	a	a	DT
cord-005603-kjcbbgse	111	28	more	more	RBR
cord-005603-kjcbbgse	111	29	severe	severe	JJ
cord-005603-kjcbbgse	111	30	one	one	CD
cord-005603-kjcbbgse	111	31	:	:	:
cord-005603-kjcbbgse	111	32	15	15	CD
cord-005603-kjcbbgse	111	33	%	%	NN
cord-005603-kjcbbgse	111	34	of	of	IN
cord-005603-kjcbbgse	111	35	patients	patient	NNS
cord-005603-kjcbbgse	111	36	with	with	IN
cord-005603-kjcbbgse	111	37	SIRS	SIRS	NNP
cord-005603-kjcbbgse	111	38	evolved	evolve	VBD
cord-005603-kjcbbgse	111	39	to	to	IN
cord-005603-kjcbbgse	111	40	sepsis	sepsis	NN
cord-005603-kjcbbgse	111	41	,	,	,
cord-005603-kjcbbgse	111	42	but	but	CC
cord-005603-kjcbbgse	111	43	only	only	RB
cord-005603-kjcbbgse	111	44	<	<	XX
cord-005603-kjcbbgse	111	45	5	5	CD
cord-005603-kjcbbgse	111	46	%	%	NN
cord-005603-kjcbbgse	111	47	to	to	IN
cord-005603-kjcbbgse	111	48	severe	severe	JJ
cord-005603-kjcbbgse	111	49	sepsis	sepsis	NN
cord-005603-kjcbbgse	111	50	,	,	,
cord-005603-kjcbbgse	111	51	while	while	IN
cord-005603-kjcbbgse	111	52	30	30	CD
cord-005603-kjcbbgse	111	53	%	%	NN
cord-005603-kjcbbgse	111	54	of	of	IN
cord-005603-kjcbbgse	111	55	patients	patient	NNS
cord-005603-kjcbbgse	111	56	with	with	IN
cord-005603-kjcbbgse	111	57	sepsis	sepsis	NN
cord-005603-kjcbbgse	111	58	evolved	evolve	VBN
cord-005603-kjcbbgse	111	59	to	to	IN
cord-005603-kjcbbgse	111	60	severe	severe	JJ
cord-005603-kjcbbgse	111	61	sepsis	sepsis	NN
cord-005603-kjcbbgse	111	62	or	or	CC
cord-005603-kjcbbgse	111	63	shock	shock	NN
cord-005603-kjcbbgse	111	64	.	.	.
cord-005603-kjcbbgse	112	1	Severe	severe	JJ
cord-005603-kjcbbgse	112	2	sepsis	sepsis	NN
cord-005603-kjcbbgse	112	3	and	and	CC
cord-005603-kjcbbgse	112	4	septic	septic	JJ
cord-005603-kjcbbgse	112	5	shock	shock	NN
cord-005603-kjcbbgse	113	1	These	these	DT
cord-005603-kjcbbgse	113	2	syndromes	syndrome	NNS
cord-005603-kjcbbgse	113	3	are	be	VBP
cord-005603-kjcbbgse	113	4	of	of	IN
cord-005603-kjcbbgse	113	5	much	much	RB
cord-005603-kjcbbgse	113	6	more	more	JJR
cord-005603-kjcbbgse	113	7	concern	concern	NN
cord-005603-kjcbbgse	113	8	to	to	IN
cord-005603-kjcbbgse	113	9	intensivists	intensivist	NNS
cord-005603-kjcbbgse	113	10	than	than	IN
cord-005603-kjcbbgse	113	11	SIRS	SIRS	NNP
cord-005603-kjcbbgse	113	12	,	,	,
cord-005603-kjcbbgse	113	13	given	give	VBN
cord-005603-kjcbbgse	113	14	their	-PRON-	PRP$
cord-005603-kjcbbgse	113	15	more	more	RBR
cord-005603-kjcbbgse	113	16	severe	severe	JJ
cord-005603-kjcbbgse	113	17	outcome	outcome	NN
cord-005603-kjcbbgse	113	18	,	,	,
cord-005603-kjcbbgse	113	19	and	and	CC
cord-005603-kjcbbgse	113	20	the	the	DT
cord-005603-kjcbbgse	113	21	poor	poor	JJ
cord-005603-kjcbbgse	113	22	specificity	specificity	NN
cord-005603-kjcbbgse	113	23	(	(	-LRB-
cord-005603-kjcbbgse	113	24	and	and	CC
cord-005603-kjcbbgse	113	25	suboptimal	suboptimal	JJ
cord-005603-kjcbbgse	113	26	sensitivity	sensitivity	NN
cord-005603-kjcbbgse	113	27	)	)	-RRB-
cord-005603-kjcbbgse	113	28	of	of	IN
cord-005603-kjcbbgse	113	29	the	the	DT
cord-005603-kjcbbgse	113	30	latter	latter	JJ
cord-005603-kjcbbgse	113	31	.	.	.
cord-005603-kjcbbgse	114	1	A	a	DT
cord-005603-kjcbbgse	114	2	closer	close	JJR
cord-005603-kjcbbgse	114	3	view	view	NN
cord-005603-kjcbbgse	114	4	of	of	IN
cord-005603-kjcbbgse	114	5	the	the	DT
cord-005603-kjcbbgse	114	6	overall	overall	JJ
cord-005603-kjcbbgse	114	7	incidence	incidence	NN
cord-005603-kjcbbgse	114	8	of	of	IN
cord-005603-kjcbbgse	114	9	these	these	DT
cord-005603-kjcbbgse	114	10	two	two	CD
cord-005603-kjcbbgse	114	11	severe	severe	JJ
cord-005603-kjcbbgse	114	12	syndromes	syndrome	NNS
cord-005603-kjcbbgse	114	13	,	,	,
cord-005603-kjcbbgse	114	14	which	which	WDT
cord-005603-kjcbbgse	114	15	are	be	VBP
cord-005603-kjcbbgse	114	16	easier	easy	JJR
cord-005603-kjcbbgse	114	17	to	to	TO
cord-005603-kjcbbgse	114	18	characterise	characterise	VB
cord-005603-kjcbbgse	114	19	in	in	IN
cord-005603-kjcbbgse	114	20	the	the	DT
cord-005603-kjcbbgse	114	21	ICU	ICU	NNP
cord-005603-kjcbbgse	114	22	,	,	,
cord-005603-kjcbbgse	114	23	has	have	VBZ
cord-005603-kjcbbgse	114	24	been	be	VBN
cord-005603-kjcbbgse	114	25	provided	provide	VBN
cord-005603-kjcbbgse	114	26	by	by	IN
cord-005603-kjcbbgse	114	27	two	two	CD
cord-005603-kjcbbgse	114	28	multicenter	multicenter	JJ
cord-005603-kjcbbgse	114	29	multi	multi	JJ
cord-005603-kjcbbgse	114	30	-	-	JJ
cord-005603-kjcbbgse	114	31	institutional	institutional	JJ
cord-005603-kjcbbgse	114	32	hospital	hospital	NN
cord-005603-kjcbbgse	114	33	-	-	HYPH
cord-005603-kjcbbgse	114	34	wide	wide	JJ
cord-005603-kjcbbgse	114	35	studies	study	NNS
cord-005603-kjcbbgse	114	36	.	.	.
cord-005603-kjcbbgse	115	1	In	in	IN
cord-005603-kjcbbgse	115	2	the	the	DT
cord-005603-kjcbbgse	115	3	French	french	JJ
cord-005603-kjcbbgse	115	4	Bacteraemia	Bacteraemia	NNP
cord-005603-kjcbbgse	115	5	/	/	SYM
cord-005603-kjcbbgse	115	6	Sepsis	Sepsis	NNP
cord-005603-kjcbbgse	115	7	study	study	NN
cord-005603-kjcbbgse	115	8	,	,	,
cord-005603-kjcbbgse	115	9	including	include	VBG
cord-005603-kjcbbgse	115	10	24	24	CD
cord-005603-kjcbbgse	115	11	hospitals	hospital	NNS
cord-005603-kjcbbgse	115	12	on	on	IN
cord-005603-kjcbbgse	115	13	the	the	DT
cord-005603-kjcbbgse	115	14	one	one	CD
cord-005603-kjcbbgse	115	15	hand	hand	NN
cord-005603-kjcbbgse	115	16	[	[	-LRB-
cord-005603-kjcbbgse	115	17	5	5	CD
cord-005603-kjcbbgse	115	18	]	]	-RRB-
cord-005603-kjcbbgse	115	19	and	and	CC
cord-005603-kjcbbgse	115	20	170	170	CD
cord-005603-kjcbbgse	115	21	ICUs	icu	NNS
cord-005603-kjcbbgse	115	22	on	on	IN
cord-005603-kjcbbgse	115	23	the	the	DT
cord-005603-kjcbbgse	115	24	other	other	JJ
cord-005603-kjcbbgse	115	25	[	[	-LRB-
cord-005603-kjcbbgse	115	26	13	13	CD
cord-005603-kjcbbgse	115	27	]	]	-RRB-
cord-005603-kjcbbgse	115	28	both	both	DT
cord-005603-kjcbbgse	115	29	surveyed	survey	VBD
cord-005603-kjcbbgse	115	30	during	during	IN
cord-005603-kjcbbgse	115	31	a	a	DT
cord-005603-kjcbbgse	115	32	2-month	2-month	JJ
cord-005603-kjcbbgse	115	33	period	period	NN
cord-005603-kjcbbgse	115	34	,	,	,
cord-005603-kjcbbgse	115	35	the	the	DT
cord-005603-kjcbbgse	115	36	overall	overall	JJ
cord-005603-kjcbbgse	115	37	incidence	incidence	NN
cord-005603-kjcbbgse	115	38	of	of	IN
cord-005603-kjcbbgse	115	39	severe	severe	JJ
cord-005603-kjcbbgse	115	40	sepsis	sepsis	NN
cord-005603-kjcbbgse	115	41	and	and	CC
cord-005603-kjcbbgse	115	42	shock	shock	NN
cord-005603-kjcbbgse	115	43	(	(	-LRB-
cord-005603-kjcbbgse	115	44	including	include	VBG
cord-005603-kjcbbgse	115	45	clinically	clinically	RB
cord-005603-kjcbbgse	115	46	and	and	CC
cord-005603-kjcbbgse	115	47	microbiologically	microbiologically	RB
cord-005603-kjcbbgse	115	48	documented	document	VBN
cord-005603-kjcbbgse	115	49	infection	infection	NN
cord-005603-kjcbbgse	115	50	)	)	-RRB-
cord-005603-kjcbbgse	115	51	was	be	VBD
cord-005603-kjcbbgse	115	52	of	of	IN
cord-005603-kjcbbgse	115	53	6/1000	6/1000	CD
cord-005603-kjcbbgse	115	54	of	of	IN
cord-005603-kjcbbgse	115	55	all	all	DT
cord-005603-kjcbbgse	115	56	hospital	hospital	NN
cord-005603-kjcbbgse	115	57	admissions	admission	NNS
cord-005603-kjcbbgse	115	58	,	,	,
cord-005603-kjcbbgse	115	59	but	but	CC
cord-005603-kjcbbgse	115	60	only	only	RB
cord-005603-kjcbbgse	115	61	of	of	IN
cord-005603-kjcbbgse	115	62	2.9/	2.9/	CD
cord-005603-kjcbbgse	115	63	1000	1000	CD
cord-005603-kjcbbgse	115	64	in	in	IN
cord-005603-kjcbbgse	115	65	medical	medical	JJ
cord-005603-kjcbbgse	115	66	/	/	SYM
cord-005603-kjcbbgse	115	67	surgical	surgical	JJ
cord-005603-kjcbbgse	115	68	wards	ward	NNS
cord-005603-kjcbbgse	115	69	and	and	CC
cord-005603-kjcbbgse	115	70	119/1000	119/1000	CD
cord-005603-kjcbbgse	115	71	in	in	IN
cord-005603-kjcbbgse	115	72	ICUs	ICUs	NNP
cord-005603-kjcbbgse	115	73	(	(	-LRB-
cord-005603-kjcbbgse	115	74	Table	Table	NNP
cord-005603-kjcbbgse	115	75	2	2	CD
cord-005603-kjcbbgse	115	76	)	)	-RRB-
cord-005603-kjcbbgse	115	77	.	.	.
cord-005603-kjcbbgse	116	1	Of	of	IN
cord-005603-kjcbbgse	116	2	note	note	VB
cord-005603-kjcbbgse	116	3	,	,	,
cord-005603-kjcbbgse	116	4	nearly	nearly	RB
cord-005603-kjcbbgse	116	5	half	half	PDT
cord-005603-kjcbbgse	116	6	the	the	DT
cord-005603-kjcbbgse	116	7	episodes	episode	NNS
cord-005603-kjcbbgse	116	8	were	be	VBD
cord-005603-kjcbbgse	116	9	of	of	IN
cord-005603-kjcbbgse	116	10	nosocomial	nosocomial	JJ
cord-005603-kjcbbgse	116	11	origin	origin	NN
cord-005603-kjcbbgse	116	12	.	.	.
cord-005603-kjcbbgse	117	1	In	in	IN
cord-005603-kjcbbgse	117	2	the	the	DT
cord-005603-kjcbbgse	117	3	parallel	parallel	JJ
cord-005603-kjcbbgse	117	4	larger	large	JJR
cord-005603-kjcbbgse	117	5	ICU	ICU	NNP
cord-005603-kjcbbgse	117	6	survey	survey	NN
cord-005603-kjcbbgse	117	7	,	,	,
cord-005603-kjcbbgse	117	8	severe	severe	JJ
cord-005603-kjcbbgse	117	9	sepsis	sepsis	NN
cord-005603-kjcbbgse	117	10	or	or	CC
cord-005603-kjcbbgse	117	11	shock	shock	NN
cord-005603-kjcbbgse	117	12	occurred	occur	VBD
cord-005603-kjcbbgse	117	13	in	in	IN
cord-005603-kjcbbgse	117	14	9	9	CD
cord-005603-kjcbbgse	117	15	%	%	NN
cord-005603-kjcbbgse	117	16	ICU	ICU	NNP
cord-005603-kjcbbgse	117	17	admissions	admission	NNS
cord-005603-kjcbbgse	117	18	;	;	:
cord-005603-kjcbbgse	117	19	71	71	CD
cord-005603-kjcbbgse	117	20	%	%	NN
cord-005603-kjcbbgse	117	21	of	of	IN
cord-005603-kjcbbgse	117	22	the	the	DT
cord-005603-kjcbbgse	117	23	1064	1064	CD
cord-005603-kjcbbgse	117	24	episodes	episode	NNS
cord-005603-kjcbbgse	117	25	were	be	VBD
cord-005603-kjcbbgse	117	26	microbiologically	microbiologically	RB
cord-005603-kjcbbgse	117	27	docu	docu	NNP
cord-005603-kjcbbgse	117	28	-	-	HYPH
cord-005603-kjcbbgse	117	29	mented	mente	VBN
cord-005603-kjcbbgse	117	30	.	.	.
cord-005603-kjcbbgse	118	1	The	the	DT
cord-005603-kjcbbgse	118	2	attack	attack	NN
cord-005603-kjcbbgse	118	3	rate	rate	NN
cord-005603-kjcbbgse	118	4	was	be	VBD
cord-005603-kjcbbgse	118	5	higher	high	JJR
cord-005603-kjcbbgse	118	6	in	in	IN
cord-005603-kjcbbgse	118	7	larger	large	JJR
cord-005603-kjcbbgse	118	8	(	(	-LRB-
cord-005603-kjcbbgse	118	9	>	>	NFP
cord-005603-kjcbbgse	118	10	400	400	CD
cord-005603-kjcbbgse	118	11	beds	bed	NNS
cord-005603-kjcbbgse	118	12	)	)	-RRB-
cord-005603-kjcbbgse	118	13	than	than	IN
cord-005603-kjcbbgse	118	14	smaller	small	JJR
cord-005603-kjcbbgse	118	15	hospitals	hospital	NNS
cord-005603-kjcbbgse	118	16	(	(	-LRB-
cord-005603-kjcbbgse	118	17	10.3	10.3	CD
cord-005603-kjcbbgse	118	18	vs.	vs.	IN
cord-005603-kjcbbgse	118	19	6.7/1000	6.7/1000	CD
cord-005603-kjcbbgse	118	20	admissions	admission	NNS
cord-005603-kjcbbgse	118	21	)	)	-RRB-
cord-005603-kjcbbgse	118	22	.	.	.
cord-005603-kjcbbgse	119	1	Septic	septic	JJ
cord-005603-kjcbbgse	119	2	shock	shock	NN
cord-005603-kjcbbgse	119	3	occurred	occur	VBD
cord-005603-kjcbbgse	119	4	in	in	IN
cord-005603-kjcbbgse	119	5	6.3/1000	6.3/1000	CD
cord-005603-kjcbbgse	119	6	ICU	ICU	NNP
cord-005603-kjcbbgse	119	7	admissions	admission	NNS
cord-005603-kjcbbgse	119	8	.	.	.
cord-005603-kjcbbgse	120	1	In	in	IN
cord-005603-kjcbbgse	120	2	the	the	DT
cord-005603-kjcbbgse	120	3	study	study	NN
cord-005603-kjcbbgse	120	4	by	by	IN
cord-005603-kjcbbgse	120	5	Sands	Sands	NNPS
cord-005603-kjcbbgse	120	6	et	et	NNP
cord-005603-kjcbbgse	120	7	al	al	NNP
cord-005603-kjcbbgse	120	8	.	.	.
cord-005603-kjcbbgse	121	1	[	[	-LRB-
cord-005603-kjcbbgse	121	2	8	8	CD
cord-005603-kjcbbgse	121	3	]	]	-RRB-
cord-005603-kjcbbgse	121	4	sepsis	sepsis	NN
cord-005603-kjcbbgse	121	5	was	be	VBD
cord-005603-kjcbbgse	121	6	noted	note	VBN
cord-005603-kjcbbgse	121	7	in	in	IN
cord-005603-kjcbbgse	121	8	20	20	CD
cord-005603-kjcbbgse	121	9	%	%	NN
cord-005603-kjcbbgse	121	10	ICU	ICU	NNP
cord-005603-kjcbbgse	121	11	patients	patient	NNS
cord-005603-kjcbbgse	121	12	and	and	CC
cord-005603-kjcbbgse	121	13	severe	severe	JJ
cord-005603-kjcbbgse	121	14	sepsis	sepsis	NN
cord-005603-kjcbbgse	121	15	(	(	-LRB-
cord-005603-kjcbbgse	121	16	defined	define	VBN
cord-005603-kjcbbgse	121	17	in	in	IN
cord-005603-kjcbbgse	121	18	that	that	DT
cord-005603-kjcbbgse	121	19	study	study	NN
cord-005603-kjcbbgse	121	20	as	as	IN
cord-005603-kjcbbgse	121	21	sepsis	sepsis	NN
cord-005603-kjcbbgse	121	22	+	+	CC
cord-005603-kjcbbgse	121	23	one	one	CD
cord-005603-kjcbbgse	121	24	of	of	IN
cord-005603-kjcbbgse	121	25	seven	seven	CD
cord-005603-kjcbbgse	121	26	criteria	criterion	NNS
cord-005603-kjcbbgse	121	27	for	for	IN
cord-005603-kjcbbgse	121	28	organ	organ	NN
cord-005603-kjcbbgse	121	29	dysfunction	dysfunction	NN
cord-005603-kjcbbgse	121	30	)	)	-RRB-
cord-005603-kjcbbgse	121	31	occurred	occur	VBD
cord-005603-kjcbbgse	121	32	in	in	IN
cord-005603-kjcbbgse	121	33	10	10	CD
cord-005603-kjcbbgse	121	34	%	%	NN
cord-005603-kjcbbgse	121	35	of	of	IN
cord-005603-kjcbbgse	121	36	ICU	ICU	NNP
cord-005603-kjcbbgse	121	37	admissions	admission	NNS
cord-005603-kjcbbgse	121	38	,	,	,
cord-005603-kjcbbgse	121	39	a	a	DT
cord-005603-kjcbbgse	121	40	figure	figure	NN
cord-005603-kjcbbgse	121	41	very	very	RB
cord-005603-kjcbbgse	121	42	close	close	RB
cord-005603-kjcbbgse	121	43	to	to	IN
cord-005603-kjcbbgse	121	44	the	the	DT
cord-005603-kjcbbgse	121	45	rate	rate	NN
cord-005603-kjcbbgse	121	46	recorded	record	VBN
cord-005603-kjcbbgse	121	47	in	in	IN
cord-005603-kjcbbgse	121	48	France	France	NNP
cord-005603-kjcbbgse	121	49	in	in	IN
cord-005603-kjcbbgse	121	50	large	large	JJ
cord-005603-kjcbbgse	121	51	hospitals	hospital	NNS
cord-005603-kjcbbgse	121	52	.	.	.
cord-005603-kjcbbgse	122	1	While	while	IN
cord-005603-kjcbbgse	122	2	nearly	nearly	RB
cord-005603-kjcbbgse	122	3	41	41	CD
cord-005603-kjcbbgse	122	4	%	%	NN
cord-005603-kjcbbgse	122	5	sepsis	sepsis	NN
cord-005603-kjcbbgse	122	6	episodes	episode	NNS
cord-005603-kjcbbgse	122	7	occurred	occur	VBD
cord-005603-kjcbbgse	122	8	in	in	IN
cord-005603-kjcbbgse	122	9	non	non	JJ
cord-005603-kjcbbgse	122	10	-	-	JJ
cord-005603-kjcbbgse	122	11	ICU	icu	JJ
cord-005603-kjcbbgse	122	12	patients	patient	NNS
cord-005603-kjcbbgse	122	13	,	,	,
cord-005603-kjcbbgse	122	14	only	only	RB
cord-005603-kjcbbgse	122	15	24	24	CD
cord-005603-kjcbbgse	122	16	%	%	NN
cord-005603-kjcbbgse	122	17	episodes	episode	NNS
cord-005603-kjcbbgse	122	18	of	of	IN
cord-005603-kjcbbgse	122	19	severe	severe	JJ
cord-005603-kjcbbgse	122	20	sepsis	sepsis	NN
cord-005603-kjcbbgse	122	21	occurred	occur	VBD
cord-005603-kjcbbgse	122	22	in	in	IN
cord-005603-kjcbbgse	122	23	such	such	JJ
cord-005603-kjcbbgse	122	24	patients	patient	NNS
cord-005603-kjcbbgse	122	25	,	,	,
cord-005603-kjcbbgse	122	26	and	and	CC
cord-005603-kjcbbgse	122	27	76	76	CD
cord-005603-kjcbbgse	122	28	%	%	NN
cord-005603-kjcbbgse	122	29	were	be	VBD
cord-005603-kjcbbgse	122	30	recorded	record	VBN
cord-005603-kjcbbgse	122	31	in	in	IN
cord-005603-kjcbbgse	122	32	ICU	ICU	NNP
cord-005603-kjcbbgse	122	33	patients	patient	NNS
cord-005603-kjcbbgse	122	34	[	[	-LRB-
cord-005603-kjcbbgse	122	35	14	14	CD
cord-005603-kjcbbgse	122	36	]	]	-RRB-
cord-005603-kjcbbgse	122	37	.	.	.
cord-005603-kjcbbgse	123	1	The	the	DT
cord-005603-kjcbbgse	123	2	relationship	relationship	NN
cord-005603-kjcbbgse	123	3	between	between	IN
cord-005603-kjcbbgse	123	4	bacteraemia	bacteraemia	NN
cord-005603-kjcbbgse	123	5	and	and	CC
cord-005603-kjcbbgse	123	6	sepsis	sepsis	NN
cord-005603-kjcbbgse	123	7	has	have	VBZ
cord-005603-kjcbbgse	123	8	been	be	VBN
cord-005603-kjcbbgse	123	9	specifically	specifically	RB
cord-005603-kjcbbgse	123	10	studied	study	VBN
cord-005603-kjcbbgse	123	11	in	in	IN
cord-005603-kjcbbgse	123	12	the	the	DT
cord-005603-kjcbbgse	123	13	French	french	JJ
cord-005603-kjcbbgse	123	14	bacteraemia	bacteraemia	NN
cord-005603-kjcbbgse	123	15	/	/	SYM
cord-005603-kjcbbgse	123	16	sepsis	sepsis	NN
cord-005603-kjcbbgse	123	17	multicenter	multicenter	JJ
cord-005603-kjcbbgse	123	18	survey	survey	NN
cord-005603-kjcbbgse	123	19	[	[	-LRB-
cord-005603-kjcbbgse	123	20	5	5	CD
cord-005603-kjcbbgse	123	21	]	]	-RRB-
cord-005603-kjcbbgse	123	22	.	.	.
cord-005603-kjcbbgse	124	1	Data	datum	NNS
cord-005603-kjcbbgse	124	2	from	from	IN
cord-005603-kjcbbgse	124	3	this	this	DT
cord-005603-kjcbbgse	124	4	study	study	NN
cord-005603-kjcbbgse	124	5	indicate	indicate	VBP
cord-005603-kjcbbgse	124	6	that	that	IN
cord-005603-kjcbbgse	124	7	only	only	RB
cord-005603-kjcbbgse	124	8	19	19	CD
cord-005603-kjcbbgse	124	9	%	%	NN
cord-005603-kjcbbgse	124	10	bacteraemic	bacteraemic	NNP
cord-005603-kjcbbgse	124	11	episodes	episode	NNS
cord-005603-kjcbbgse	124	12	occurred	occur	VBD
cord-005603-kjcbbgse	124	13	in	in	IN
cord-005603-kjcbbgse	124	14	ICUs	ICUs	NNP
cord-005603-kjcbbgse	124	15	,	,	,
cord-005603-kjcbbgse	124	16	while	while	IN
cord-005603-kjcbbgse	124	17	81	81	CD
cord-005603-kjcbbgse	124	18	%	%	NN
cord-005603-kjcbbgse	124	19	occurred	occur	VBD
cord-005603-kjcbbgse	124	20	in	in	IN
cord-005603-kjcbbgse	124	21	wards	ward	NNS
cord-005603-kjcbbgse	124	22	,	,	,
cord-005603-kjcbbgse	124	23	including	include	VBG
cord-005603-kjcbbgse	124	24	63	63	CD
cord-005603-kjcbbgse	124	25	%	%	NN
cord-005603-kjcbbgse	124	26	in	in	IN
cord-005603-kjcbbgse	124	27	medical	medical	JJ
cord-005603-kjcbbgse	124	28	wards	ward	NNS
cord-005603-kjcbbgse	124	29	,	,	,
cord-005603-kjcbbgse	124	30	and	and	CC
cord-005603-kjcbbgse	124	31	18	18	CD
cord-005603-kjcbbgse	124	32	%	%	NN
cord-005603-kjcbbgse	124	33	in	in	IN
cord-005603-kjcbbgse	124	34	surgical	surgical	JJ
cord-005603-kjcbbgse	124	35	wards	ward	NNS
cord-005603-kjcbbgse	124	36	.	.	.
cord-005603-kjcbbgse	125	1	Sepsis	sepsis	NN
cord-005603-kjcbbgse	125	2	was	be	VBD
cord-005603-kjcbbgse	125	3	recorded	record	VBN
cord-005603-kjcbbgse	125	4	in	in	IN
cord-005603-kjcbbgse	125	5	74	74	CD
cord-005603-kjcbbgse	125	6	%	%	NN
cord-005603-kjcbbgse	125	7	of	of	IN
cord-005603-kjcbbgse	125	8	bacteraemic	bacteraemic	NNP
cord-005603-kjcbbgse	125	9	episodes	episode	NNS
cord-005603-kjcbbgse	125	10	,	,	,
cord-005603-kjcbbgse	125	11	severe	severe	JJ
cord-005603-kjcbbgse	125	12	sepsis	sepsis	NN
cord-005603-kjcbbgse	125	13	in	in	IN
cord-005603-kjcbbgse	125	14	26	26	CD
cord-005603-kjcbbgse	125	15	%	%	NN
cord-005603-kjcbbgse	125	16	,	,	,
cord-005603-kjcbbgse	125	17	of	of	IN
cord-005603-kjcbbgse	125	18	which	which	WDT
cord-005603-kjcbbgse	125	19	60	60	CD
cord-005603-kjcbbgse	125	20	%	%	NN
cord-005603-kjcbbgse	125	21	were	be	VBD
cord-005603-kjcbbgse	125	22	associated	associate	VBN
cord-005603-kjcbbgse	125	23	with	with	IN
cord-005603-kjcbbgse	125	24	septic	septic	JJ
cord-005603-kjcbbgse	125	25	shock	shock	NN
cord-005603-kjcbbgse	125	26	(	(	-LRB-
cord-005603-kjcbbgse	125	27	16	16	CD
cord-005603-kjcbbgse	125	28	%	%	NN
cord-005603-kjcbbgse	125	29	of	of	IN
cord-005603-kjcbbgse	125	30	all	all	DT
cord-005603-kjcbbgse	125	31	bacteraemic	bacteraemic	NNP
cord-005603-kjcbbgse	125	32	episodes	episode	NNS
cord-005603-kjcbbgse	125	33	)	)	-RRB-
cord-005603-kjcbbgse	125	34	.	.	.
cord-005603-kjcbbgse	126	1	However	however	RB
cord-005603-kjcbbgse	126	2	,	,	,
cord-005603-kjcbbgse	126	3	the	the	DT
cord-005603-kjcbbgse	126	4	prevalence	prevalence	NN
cord-005603-kjcbbgse	126	5	of	of	IN
cord-005603-kjcbbgse	126	6	severe	severe	JJ
cord-005603-kjcbbgse	126	7	sepsis	sepsis	NN
cord-005603-kjcbbgse	126	8	during	during	IN
cord-005603-kjcbbgse	126	9	bacteraemia	bacteraemia	NN
cord-005603-kjcbbgse	126	10	was	be	VBD
cord-005603-kjcbbgse	126	11	much	much	RB
cord-005603-kjcbbgse	126	12	higher	high	JJR
cord-005603-kjcbbgse	126	13	in	in	IN
cord-005603-kjcbbgse	126	14	ICUs	icus	NN
cord-005603-kjcbbgse	126	15	than	than	IN
cord-005603-kjcbbgse	126	16	in	in	IN
cord-005603-kjcbbgse	126	17	medical	medical	JJ
cord-005603-kjcbbgse	126	18	/	/	SYM
cord-005603-kjcbbgse	126	19	surgical	surgical	JJ
cord-005603-kjcbbgse	126	20	wards	ward	NNS
cord-005603-kjcbbgse	126	21	(	(	-LRB-
cord-005603-kjcbbgse	126	22	65	65	CD
cord-005603-kjcbbgse	126	23	%	%	NN
cord-005603-kjcbbgse	126	24	vs.	vs.	IN
cord-005603-kjcbbgse	126	25	17	17	CD
cord-005603-kjcbbgse	126	26	%	%	NN
cord-005603-kjcbbgse	126	27	of	of	IN
cord-005603-kjcbbgse	126	28	bacteraemic	bacteraemic	NNP
cord-005603-kjcbbgse	126	29	episodes	episode	NNS
cord-005603-kjcbbgse	126	30	,	,	,
cord-005603-kjcbbgse	126	31	P	p	NN
cord-005603-kjcbbgse	126	32	<	<	XX
cord-005603-kjcbbgse	126	33	0.001	0.001	CD
cord-005603-kjcbbgse	126	34	)	)	-RRB-
cord-005603-kjcbbgse	126	35	,	,	,
cord-005603-kjcbbgse	126	36	emphasising	emphasise	VBG
cord-005603-kjcbbgse	126	37	the	the	DT
cord-005603-kjcbbgse	126	38	much	much	RB
cord-005603-kjcbbgse	126	39	higher	high	JJR
cord-005603-kjcbbgse	126	40	risk	risk	NN
cord-005603-kjcbbgse	126	41	of	of	IN
cord-005603-kjcbbgse	126	42	organ	organ	NN
cord-005603-kjcbbgse	126	43	dysfunction	dysfunction	NN
cord-005603-kjcbbgse	126	44	and	and	CC
cord-005603-kjcbbgse	126	45	shock	shock	NN
cord-005603-kjcbbgse	126	46	during	during	IN
cord-005603-kjcbbgse	126	47	bacteraemia	bacteraemia	NNP
cord-005603-kjcbbgse	126	48	in	in	IN
cord-005603-kjcbbgse	126	49	critically	critically	RB
cord-005603-kjcbbgse	126	50	ill	ill	JJ
cord-005603-kjcbbgse	126	51	patients	patient	NNS
cord-005603-kjcbbgse	126	52	.	.	.
cord-005603-kjcbbgse	127	1	Conversely	conversely	RB
cord-005603-kjcbbgse	127	2	,	,	,
cord-005603-kjcbbgse	127	3	the	the	DT
cord-005603-kjcbbgse	127	4	prevalence	prevalence	NN
cord-005603-kjcbbgse	127	5	of	of	IN
cord-005603-kjcbbgse	127	6	bacteraemia	bacteraemia	NN
cord-005603-kjcbbgse	127	7	during	during	IN
cord-005603-kjcbbgse	127	8	severe	severe	JJ
cord-005603-kjcbbgse	127	9	sepsis	sepsis	NN
cord-005603-kjcbbgse	127	10	was	be	VBD
cord-005603-kjcbbgse	127	11	estimated	estimate	VBN
cord-005603-kjcbbgse	127	12	at	at	IN
cord-005603-kjcbbgse	127	13	38	38	CD
cord-005603-kjcbbgse	127	14	%	%	NN
cord-005603-kjcbbgse	127	15	by	by	IN
cord-005603-kjcbbgse	127	16	Kieft	Kieft	NNP
cord-005603-kjcbbgse	127	17	et	et	NNP
cord-005603-kjcbbgse	127	18	al	al	NNP
cord-005603-kjcbbgse	127	19	.	.	.
cord-005603-kjcbbgse	128	1	[	[	-LRB-
cord-005603-kjcbbgse	128	2	15	15	CD
cord-005603-kjcbbgse	128	3	]	]	-RRB-
cord-005603-kjcbbgse	128	4	at	at	IN
cord-005603-kjcbbgse	128	5	43	43	CD
cord-005603-kjcbbgse	128	6	%	%	NN
cord-005603-kjcbbgse	128	7	in	in	IN
cord-005603-kjcbbgse	128	8	the	the	DT
cord-005603-kjcbbgse	128	9	French	french	JJ
cord-005603-kjcbbgse	128	10	multicenter	multicenter	JJ
cord-005603-kjcbbgse	128	11	study	study	NN
cord-005603-kjcbbgse	128	12	[	[	-LRB-
cord-005603-kjcbbgse	128	13	5	5	CD
cord-005603-kjcbbgse	128	14	]	]	-RRB-
cord-005603-kjcbbgse	128	15	and	and	CC
cord-005603-kjcbbgse	128	16	at	at	IN
cord-005603-kjcbbgse	128	17	32.5	32.5	CD
cord-005603-kjcbbgse	128	18	%	%	NN
cord-005603-kjcbbgse	128	19	of	of	IN
cord-005603-kjcbbgse	128	20	episodes	episode	NNS
cord-005603-kjcbbgse	128	21	in	in	IN
cord-005603-kjcbbgse	128	22	the	the	DT
cord-005603-kjcbbgse	128	23	study	study	NN
cord-005603-kjcbbgse	128	24	conducted	conduct	VBN
cord-005603-kjcbbgse	128	25	by	by	IN
cord-005603-kjcbbgse	128	26	Sands	Sands	NNPS
cord-005603-kjcbbgse	128	27	et	et	NNP
cord-005603-kjcbbgse	128	28	al	al	NNP
cord-005603-kjcbbgse	128	29	.	.	.
cord-005603-kjcbbgse	129	1	[	[	-LRB-
cord-005603-kjcbbgse	129	2	8	8	CD
cord-005603-kjcbbgse	129	3	]	]	-RRB-
cord-005603-kjcbbgse	129	4	.	.	.
cord-005603-kjcbbgse	130	1	Rangel	Rangel	NNP
cord-005603-kjcbbgse	130	2	-	-	HYPH
cord-005603-kjcbbgse	130	3	Frausto	Frausto	NNP
cord-005603-kjcbbgse	130	4	et	et	NNP
cord-005603-kjcbbgse	130	5	al	al	NNP
cord-005603-kjcbbgse	130	6	.	.	.
cord-005603-kjcbbgse	131	1	,	,	,
cord-005603-kjcbbgse	131	2	recorded	record	VBN
cord-005603-kjcbbgse	131	3	bacteraemia	bacteraemia	NN
cord-005603-kjcbbgse	131	4	in	in	IN
cord-005603-kjcbbgse	131	5	17	17	CD
cord-005603-kjcbbgse	131	6	%	%	NN
cord-005603-kjcbbgse	131	7	of	of	IN
cord-005603-kjcbbgse	131	8	patients	patient	NNS
cord-005603-kjcbbgse	131	9	with	with	IN
cord-005603-kjcbbgse	131	10	sepsis	sepsis	NN
cord-005603-kjcbbgse	131	11	,	,	,
cord-005603-kjcbbgse	131	12	25	25	CD
cord-005603-kjcbbgse	131	13	%	%	NN
cord-005603-kjcbbgse	131	14	of	of	IN
cord-005603-kjcbbgse	131	15	those	those	DT
cord-005603-kjcbbgse	131	16	with	with	IN
cord-005603-kjcbbgse	131	17	severe	severe	JJ
cord-005603-kjcbbgse	131	18	sepsis	sepsis	NN
cord-005603-kjcbbgse	131	19	,	,	,
cord-005603-kjcbbgse	131	20	and	and	CC
cord-005603-kjcbbgse	131	21	69	69	CD
cord-005603-kjcbbgse	131	22	%	%	NN
cord-005603-kjcbbgse	131	23	of	of	IN
cord-005603-kjcbbgse	131	24	patients	patient	NNS
cord-005603-kjcbbgse	131	25	with	with	IN
cord-005603-kjcbbgse	131	26	septic	septic	JJ
cord-005603-kjcbbgse	131	27	shock	shock	NN
cord-005603-kjcbbgse	131	28	[	[	-LRB-
cord-005603-kjcbbgse	131	29	6	6	CD
cord-005603-kjcbbgse	131	30	]	]	-RRB-
cord-005603-kjcbbgse	131	31	.	.	.
cord-005603-kjcbbgse	132	1	In	in	IN
cord-005603-kjcbbgse	132	2	non	non	JJ
cord-005603-kjcbbgse	132	3	-	-	JJ
cord-005603-kjcbbgse	132	4	ICU	icu	JJ
cord-005603-kjcbbgse	132	5	patients	patient	NNS
cord-005603-kjcbbgse	132	6	,	,	,
cord-005603-kjcbbgse	132	7	the	the	DT
cord-005603-kjcbbgse	132	8	prevalence	prevalence	NN
cord-005603-kjcbbgse	132	9	of	of	IN
cord-005603-kjcbbgse	132	10	bacteraemia	bacteraemia	NN
cord-005603-kjcbbgse	132	11	during	during	IN
cord-005603-kjcbbgse	132	12	severe	severe	JJ
cord-005603-kjcbbgse	132	13	sepsis	sepsis	NN
cord-005603-kjcbbgse	132	14	was	be	VBD
cord-005603-kjcbbgse	132	15	estimated	estimate	VBN
cord-005603-kjcbbgse	132	16	at	at	IN
cord-005603-kjcbbgse	132	17	48	48	CD
cord-005603-kjcbbgse	132	18	%	%	NN
cord-005603-kjcbbgse	132	19	,	,	,
cord-005603-kjcbbgse	132	20	compared	compare	VBN
cord-005603-kjcbbgse	132	21	to	to	IN
cord-005603-kjcbbgse	132	22	38	38	CD
cord-005603-kjcbbgse	132	23	%	%	NN
cord-005603-kjcbbgse	132	24	in	in	IN
cord-005603-kjcbbgse	132	25	ICU	ICU	NNP
cord-005603-kjcbbgse	132	26	patients	patient	NNS
cord-005603-kjcbbgse	132	27	[	[	-LRB-
cord-005603-kjcbbgse	132	28	13	13	CD
cord-005603-kjcbbgse	132	29	]	]	-RRB-
cord-005603-kjcbbgse	132	30	.	.	.
cord-005603-kjcbbgse	133	1	Likewise	likewise	RB
cord-005603-kjcbbgse	133	2	,	,	,
cord-005603-kjcbbgse	133	3	Sands	Sands	NNPS
cord-005603-kjcbbgse	133	4	et	et	NNP
cord-005603-kjcbbgse	133	5	al	al	NNP
cord-005603-kjcbbgse	133	6	.	.	NNP
cord-005603-kjcbbgse	133	7	,	,	,
cord-005603-kjcbbgse	133	8	found	find	VBD
cord-005603-kjcbbgse	133	9	a	a	DT
cord-005603-kjcbbgse	133	10	prevalence	prevalence	NN
cord-005603-kjcbbgse	133	11	of	of	IN
cord-005603-kjcbbgse	133	12	bacteraemia	bacteraemia	NN
cord-005603-kjcbbgse	133	13	during	during	IN
cord-005603-kjcbbgse	133	14	severe	severe	JJ
cord-005603-kjcbbgse	133	15	sepsis	sepsis	NN
cord-005603-kjcbbgse	133	16	of	of	IN
cord-005603-kjcbbgse	133	17	50	50	CD
cord-005603-kjcbbgse	133	18	%	%	NN
cord-005603-kjcbbgse	133	19	in	in	IN
cord-005603-kjcbbgse	133	20	non	non	JJ
cord-005603-kjcbbgse	133	21	-	-	JJ
cord-005603-kjcbbgse	133	22	ICU	icu	JJ
cord-005603-kjcbbgse	133	23	patients	patient	NNS
cord-005603-kjcbbgse	133	24	and	and	CC
cord-005603-kjcbbgse	133	25	of	of	IN
cord-005603-kjcbbgse	133	26	26	26	CD
cord-005603-kjcbbgse	133	27	%	%	NN
cord-005603-kjcbbgse	133	28	in	in	IN
cord-005603-kjcbbgse	133	29	ICU	ICU	NNP
cord-005603-kjcbbgse	133	30	patients	patient	NNS
cord-005603-kjcbbgse	133	31	[	[	-LRB-
cord-005603-kjcbbgse	133	32	8	8	CD
cord-005603-kjcbbgse	133	33	,	,	,
cord-005603-kjcbbgse	133	34	14	14	CD
cord-005603-kjcbbgse	133	35	]	]	-RRB-
cord-005603-kjcbbgse	133	36	.	.	.
cord-005603-kjcbbgse	134	1	These	these	DT
cord-005603-kjcbbgse	134	2	data	datum	NNS
cord-005603-kjcbbgse	134	3	indicate	indicate	VBP
cord-005603-kjcbbgse	134	4	that	that	IN
cord-005603-kjcbbgse	134	5	,	,	,
cord-005603-kjcbbgse	134	6	although	although	IN
cord-005603-kjcbbgse	134	7	ICU	ICU	NNP
cord-005603-kjcbbgse	134	8	patients	patient	NNS
cord-005603-kjcbbgse	134	9	are	be	VBP
cord-005603-kjcbbgse	134	10	at	at	IN
cord-005603-kjcbbgse	134	11	much	much	RB
cord-005603-kjcbbgse	134	12	higher	high	JJR
cord-005603-kjcbbgse	134	13	risk	risk	NN
cord-005603-kjcbbgse	134	14	of	of	IN
cord-005603-kjcbbgse	134	15	severe	severe	JJ
cord-005603-kjcbbgse	134	16	sepsis	sepsis	NN
cord-005603-kjcbbgse	134	17	than	than	IN
cord-005603-kjcbbgse	134	18	ward	ward	NN
cord-005603-kjcbbgse	134	19	patients	patient	NNS
cord-005603-kjcbbgse	134	20	,	,	,
cord-005603-kjcbbgse	134	21	bacteraemic	bacteraemic	NNP
cord-005603-kjcbbgse	134	22	severe	severe	JJ
cord-005603-kjcbbgse	134	23	sepsis	sepsis	NN
cord-005603-kjcbbgse	134	24	is	be	VBZ
cord-005603-kjcbbgse	134	25	proportionally	proportionally	RB
cord-005603-kjcbbgse	134	26	less	less	RBR
cord-005603-kjcbbgse	134	27	often	often	RB
cord-005603-kjcbbgse	134	28	encountered	encounter	VBN
cord-005603-kjcbbgse	134	29	in	in	IN
cord-005603-kjcbbgse	134	30	ICU	ICU	NNP
cord-005603-kjcbbgse	134	31	than	than	IN
cord-005603-kjcbbgse	134	32	in	in	IN
cord-005603-kjcbbgse	134	33	non	non	JJ
cord-005603-kjcbbgse	134	34	-	-	JJ
cord-005603-kjcbbgse	134	35	ICU	icu	JJ
cord-005603-kjcbbgse	134	36	patients	patient	NNS
cord-005603-kjcbbgse	134	37	.	.	.
cord-005603-kjcbbgse	135	1	Factors	factor	NNS
cord-005603-kjcbbgse	135	2	associated	associate	VBN
cord-005603-kjcbbgse	135	3	with	with	IN
cord-005603-kjcbbgse	135	4	bacteraemia	bacteraemia	NN
cord-005603-kjcbbgse	135	5	at	at	IN
cord-005603-kjcbbgse	135	6	the	the	DT
cord-005603-kjcbbgse	135	7	onset	onset	NN
cord-005603-kjcbbgse	135	8	of	of	IN
cord-005603-kjcbbgse	135	9	sepsis	sepsis	NN
cord-005603-kjcbbgse	135	10	have	have	VBP
cord-005603-kjcbbgse	135	11	been	be	VBN
cord-005603-kjcbbgse	135	12	examined	examine	VBN
cord-005603-kjcbbgse	135	13	in	in	IN
cord-005603-kjcbbgse	135	14	the	the	DT
cord-005603-kjcbbgse	135	15	study	study	NN
cord-005603-kjcbbgse	135	16	conducted	conduct	VBN
cord-005603-kjcbbgse	135	17	by	by	IN
cord-005603-kjcbbgse	135	18	Sands	Sands	NNPS
cord-005603-kjcbbgse	135	19	et	et	NNP
cord-005603-kjcbbgse	135	20	al	al	NNP
cord-005603-kjcbbgse	135	21	.	.	.
cord-005603-kjcbbgse	136	1	[	[	-LRB-
cord-005603-kjcbbgse	136	2	14	14	CD
cord-005603-kjcbbgse	136	3	]	]	-RRB-
cord-005603-kjcbbgse	136	4	.	.	.
cord-005603-kjcbbgse	137	1	Independent	independent	JJ
cord-005603-kjcbbgse	137	2	predictors	predictor	NNS
cord-005603-kjcbbgse	137	3	of	of	IN
cord-005603-kjcbbgse	137	4	bacteraemia	bacteraemia	NN
cord-005603-kjcbbgse	137	5	during	during	IN
cord-005603-kjcbbgse	137	6	sepsis	sepsis	NN
cord-005603-kjcbbgse	137	7	were	be	VBD
cord-005603-kjcbbgse	137	8	:	:	:
cord-005603-kjcbbgse	137	9	a	a	DT
cord-005603-kjcbbgse	137	10	suspected	suspect	VBN
cord-005603-kjcbbgse	137	11	or	or	CC
cord-005603-kjcbbgse	137	12	documented	document	VBN
cord-005603-kjcbbgse	137	13	focal	focal	JJ
cord-005603-kjcbbgse	137	14	infection	infection	NN
cord-005603-kjcbbgse	137	15	,	,	,
cord-005603-kjcbbgse	137	16	absence	absence	NN
cord-005603-kjcbbgse	137	17	of	of	IN
cord-005603-kjcbbgse	137	18	antibiotic	antibiotic	JJ
cord-005603-kjcbbgse	137	19	therapy	therapy	NN
cord-005603-kjcbbgse	137	20	,	,	,
cord-005603-kjcbbgse	137	21	presence	presence	NN
cord-005603-kjcbbgse	137	22	of	of	IN
cord-005603-kjcbbgse	137	23	liver	liver	NN
cord-005603-kjcbbgse	137	24	disease	disease	NN
cord-005603-kjcbbgse	137	25	,	,	,
cord-005603-kjcbbgse	137	26	of	of	IN
cord-005603-kjcbbgse	137	27	a	a	DT
cord-005603-kjcbbgse	137	28	Hickman	Hickman	NNP
cord-005603-kjcbbgse	137	29	catheter	catheter	NN
cord-005603-kjcbbgse	137	30	,	,	,
cord-005603-kjcbbgse	137	31	altered	alter	VBN
cord-005603-kjcbbgse	137	32	mental	mental	JJ
cord-005603-kjcbbgse	137	33	status	status	NN
cord-005603-kjcbbgse	137	34	,	,	,
cord-005603-kjcbbgse	137	35	and	and	CC
cord-005603-kjcbbgse	137	36	focal	focal	JJ
cord-005603-kjcbbgse	137	37	abdominal	abdominal	JJ
cord-005603-kjcbbgse	137	38	signs	sign	NNS
cord-005603-kjcbbgse	137	39	.	.	.
cord-005603-kjcbbgse	138	1	Infection	infection	NN
cord-005603-kjcbbgse	138	2	caused	cause	VBN
cord-005603-kjcbbgse	138	3	by	by	IN
cord-005603-kjcbbgse	138	4	staphylococci	staphylococcus	NNS
cord-005603-kjcbbgse	138	5	were	be	VBD
cord-005603-kjcbbgse	138	6	associated	associate	VBN
cord-005603-kjcbbgse	138	7	with	with	IN
cord-005603-kjcbbgse	138	8	hemodialysis	hemodialysis	NN
cord-005603-kjcbbgse	138	9	and	and	CC
cord-005603-kjcbbgse	138	10	mechanical	mechanical	JJ
cord-005603-kjcbbgse	138	11	ventilation	ventilation	NN
cord-005603-kjcbbgse	138	12	,	,	,
cord-005603-kjcbbgse	138	13	while	while	IN
cord-005603-kjcbbgse	138	14	gram	gram	NN
cord-005603-kjcbbgse	138	15	-	-	HYPH
cord-005603-kjcbbgse	138	16	negative	negative	JJ
cord-005603-kjcbbgse	138	17	infection	infection	NN
cord-005603-kjcbbgse	138	18	were	be	VBD
cord-005603-kjcbbgse	138	19	associated	associate	VBN
cord-005603-kjcbbgse	138	20	with	with	IN
cord-005603-kjcbbgse	138	21	the	the	DT
cord-005603-kjcbbgse	138	22	use	use	NN
cord-005603-kjcbbgse	138	23	of	of	IN
cord-005603-kjcbbgse	138	24	TPN	TPN	NNP
cord-005603-kjcbbgse	138	25	,	,	,
cord-005603-kjcbbgse	138	26	the	the	DT
cord-005603-kjcbbgse	138	27	absence	absence	NN
cord-005603-kjcbbgse	138	28	of	of	IN
cord-005603-kjcbbgse	138	29	antibiotic	antibiotic	JJ
cord-005603-kjcbbgse	138	30	therapy	therapy	NN
cord-005603-kjcbbgse	138	31	,	,	,
cord-005603-kjcbbgse	138	32	the	the	DT
cord-005603-kjcbbgse	138	33	presence	presence	NN
cord-005603-kjcbbgse	138	34	of	of	IN
cord-005603-kjcbbgse	138	35	a	a	DT
cord-005603-kjcbbgse	138	36	Hickman	Hickman	NNP
cord-005603-kjcbbgse	138	37	catheter	catheter	NN
cord-005603-kjcbbgse	138	38	,	,	,
cord-005603-kjcbbgse	138	39	of	of	IN
cord-005603-kjcbbgse	138	40	focal	focal	JJ
cord-005603-kjcbbgse	138	41	abdominal	abdominal	JJ
cord-005603-kjcbbgse	138	42	signs	sign	NNS
cord-005603-kjcbbgse	138	43	,	,	,
cord-005603-kjcbbgse	138	44	and	and	CC
cord-005603-kjcbbgse	138	45	of	of	IN
cord-005603-kjcbbgse	138	46	chills	chill	NNS
cord-005603-kjcbbgse	138	47	[	[	-LRB-
cord-005603-kjcbbgse	138	48	14	14	CD
cord-005603-kjcbbgse	138	49	]	]	-RRB-
cord-005603-kjcbbgse	138	50	.	.	.
cord-005603-kjcbbgse	139	1	The	the	DT
cord-005603-kjcbbgse	139	2	prediction	prediction	NN
cord-005603-kjcbbgse	139	3	rules	rule	NNS
cord-005603-kjcbbgse	139	4	derived	derive	VBN
cord-005603-kjcbbgse	139	5	from	from	IN
cord-005603-kjcbbgse	139	6	these	these	DT
cord-005603-kjcbbgse	139	7	data	datum	NNS
cord-005603-kjcbbgse	139	8	performed	perform	VBD
cord-005603-kjcbbgse	139	9	reasonably	reasonably	RB
cord-005603-kjcbbgse	139	10	well	well	RB
cord-005603-kjcbbgse	139	11	,	,	,
cord-005603-kjcbbgse	139	12	although	although	IN
cord-005603-kjcbbgse	139	13	the	the	DT
cord-005603-kjcbbgse	139	14	rates	rate	NNS
cord-005603-kjcbbgse	139	15	of	of	IN
cord-005603-kjcbbgse	139	16	bacteraemia	bacteraemia	NN
cord-005603-kjcbbgse	139	17	in	in	IN
cord-005603-kjcbbgse	139	18	the	the	DT
cord-005603-kjcbbgse	139	19	highest	high	JJS
cord-005603-kjcbbgse	139	20	-	-	HYPH
cord-005603-kjcbbgse	139	21	risk	risk	NN
cord-005603-kjcbbgse	139	22	groups	group	NNS
cord-005603-kjcbbgse	139	23	varied	vary	VBN
cord-005603-kjcbbgse	139	24	from	from	IN
cord-005603-kjcbbgse	139	25	only	only	RB
cord-005603-kjcbbgse	139	26	20	20	CD
cord-005603-kjcbbgse	139	27	%	%	NN
cord-005603-kjcbbgse	139	28	to	to	TO
cord-005603-kjcbbgse	139	29	60	60	CD
cord-005603-kjcbbgse	139	30	%	%	NN
cord-005603-kjcbbgse	139	31	,	,	,
cord-005603-kjcbbgse	139	32	depending	depend	VBG
cord-005603-kjcbbgse	139	33	on	on	IN
cord-005603-kjcbbgse	139	34	the	the	DT
cord-005603-kjcbbgse	139	35	source	source	NN
cord-005603-kjcbbgse	139	36	and	and	CC
cord-005603-kjcbbgse	139	37	micro	micro	NNS
cord-005603-kjcbbgse	139	38	-	-	NNS
cord-005603-kjcbbgse	139	39	organisms	organism	NNS
cord-005603-kjcbbgse	139	40	involved	involve	VBN
cord-005603-kjcbbgse	139	41	.	.	.
cord-005603-kjcbbgse	140	1	Host	host	NN
cord-005603-kjcbbgse	140	2	factors	factor	NNS
cord-005603-kjcbbgse	140	3	identified	identify	VBD
cord-005603-kjcbbgse	140	4	(	(	-LRB-
cord-005603-kjcbbgse	140	5	by	by	IN
cord-005603-kjcbbgse	140	6	multivariate	multivariate	JJ
cord-005603-kjcbbgse	140	7	analysis	analysis	NN
cord-005603-kjcbbgse	140	8	)	)	-RRB-
cord-005603-kjcbbgse	140	9	as	as	RB
cord-005603-kjcbbgse	140	10	independently	independently	RB
cord-005603-kjcbbgse	140	11	associated	associate	VBN
cord-005603-kjcbbgse	140	12	with	with	IN
cord-005603-kjcbbgse	140	13	severe	severe	JJ
cord-005603-kjcbbgse	140	14	sepsis	sepsis	NN
cord-005603-kjcbbgse	140	15	among	among	IN
cord-005603-kjcbbgse	140	16	the	the	DT
cord-005603-kjcbbgse	140	17	11	11	CD
cord-005603-kjcbbgse	140	18	740	740	CD
cord-005603-kjcbbgse	140	19	admissions	admission	NNS
cord-005603-kjcbbgse	140	20	to	to	IN
cord-005603-kjcbbgse	140	21	the	the	DT
cord-005603-kjcbbgse	140	22	170	170	CD
cord-005603-kjcbbgse	140	23	ICUs	icu	NNS
cord-005603-kjcbbgse	140	24	participating	participate	VBG
cord-005603-kjcbbgse	140	25	in	in	IN
cord-005603-kjcbbgse	140	26	the	the	DT
cord-005603-kjcbbgse	140	27	French	french	JJ
cord-005603-kjcbbgse	140	28	bacteraemia	bacteraemia	NN
cord-005603-kjcbbgse	140	29	/	/	SYM
cord-005603-kjcbbgse	140	30	sepsis	sepsis	NN
cord-005603-kjcbbgse	140	31	study	study	NN
cord-005603-kjcbbgse	140	32	were	be	VBD
cord-005603-kjcbbgse	140	33	:	:	:
cord-005603-kjcbbgse	140	34	age	age	NN
cord-005603-kjcbbgse	140	35	,	,	,
cord-005603-kjcbbgse	140	36	male	male	JJ
cord-005603-kjcbbgse	140	37	sex	sex	NN
cord-005603-kjcbbgse	140	38	,	,	,
cord-005603-kjcbbgse	140	39	admission	admission	NN
cord-005603-kjcbbgse	140	40	to	to	IN
cord-005603-kjcbbgse	140	41	a	a	DT
cord-005603-kjcbbgse	140	42	large	large	JJ
cord-005603-kjcbbgse	140	43	(	(	-LRB-
cord-005603-kjcbbgse	140	44	>	>	NFP
cord-005603-kjcbbgse	140	45	400	400	CD
cord-005603-kjcbbgse	140	46	beds	bed	NNS
cord-005603-kjcbbgse	140	47	)	)	-RRB-
cord-005603-kjcbbgse	140	48	hospital	hospital	NN
cord-005603-kjcbbgse	140	49	,	,	,
cord-005603-kjcbbgse	140	50	a	a	DT
cord-005603-kjcbbgse	140	51	medical	medical	JJ
cord-005603-kjcbbgse	140	52	or	or	CC
cord-005603-kjcbbgse	140	53	unscheduled	unscheduled	JJ
cord-005603-kjcbbgse	140	54	surgical	surgical	JJ
cord-005603-kjcbbgse	140	55	admission	admission	NN
cord-005603-kjcbbgse	140	56	,	,	,
cord-005603-kjcbbgse	140	57	presence	presence	NN
cord-005603-kjcbbgse	140	58	of	of	IN
cord-005603-kjcbbgse	140	59	chronic	chronic	JJ
cord-005603-kjcbbgse	140	60	liver	liver	NN
cord-005603-kjcbbgse	140	61	insufficiency	insufficiency	NN
cord-005603-kjcbbgse	140	62	,	,	,
cord-005603-kjcbbgse	140	63	of	of	IN
cord-005603-kjcbbgse	140	64	immunodepression	immunodepression	NN
cord-005603-kjcbbgse	140	65	,	,	,
cord-005603-kjcbbgse	140	66	and	and	CC
cord-005603-kjcbbgse	140	67	of	of	IN
cord-005603-kjcbbgse	140	68	severe	severe	JJ
cord-005603-kjcbbgse	140	69	underlying	underlie	VBG
cord-005603-kjcbbgse	140	70	disease	disease	NN
cord-005603-kjcbbgse	140	71	[	[	-LRB-
cord-005603-kjcbbgse	140	72	13	13	CD
cord-005603-kjcbbgse	140	73	]	]	-RRB-
cord-005603-kjcbbgse	140	74	.	.	.
cord-005603-kjcbbgse	141	1	There	there	EX
cord-005603-kjcbbgse	141	2	was	be	VBD
cord-005603-kjcbbgse	141	3	no	no	DT
cord-005603-kjcbbgse	141	4	difference	difference	NN
cord-005603-kjcbbgse	141	5	in	in	IN
cord-005603-kjcbbgse	141	6	these	these	DT
cord-005603-kjcbbgse	141	7	risk	risk	NN
cord-005603-kjcbbgse	141	8	factors	factor	NNS
cord-005603-kjcbbgse	141	9	when	when	WRB
cord-005603-kjcbbgse	141	10	excluding	exclude	VBG
cord-005603-kjcbbgse	141	11	patients	patient	NNS
cord-005603-kjcbbgse	141	12	with	with	IN
cord-005603-kjcbbgse	141	13	non	non	JJ
cord-005603-kjcbbgse	141	14	-	-	JJ
cord-005603-kjcbbgse	141	15	documented	documented	JJ
cord-005603-kjcbbgse	141	16	severe	severe	JJ
cord-005603-kjcbbgse	141	17	sepsis	sepsis	NN
cord-005603-kjcbbgse	141	18	(	(	-LRB-
cord-005603-kjcbbgse	142	1	i.	i.	NNP
cord-005603-kjcbbgse	142	2	e.	e.	NNP
cord-005603-kjcbbgse	143	1	,	,	,
cord-005603-kjcbbgse	143	2	`	`	''
cord-005603-kjcbbgse	143	3	severe	severe	JJ
cord-005603-kjcbbgse	143	4	SIRS	SIRS	NNP
cord-005603-kjcbbgse	143	5	'	'	''
cord-005603-kjcbbgse	143	6	)	)	-RRB-
cord-005603-kjcbbgse	143	7	from	from	IN
cord-005603-kjcbbgse	143	8	the	the	DT
cord-005603-kjcbbgse	143	9	cohort	cohort	NN
cord-005603-kjcbbgse	143	10	.	.	.
cord-005603-kjcbbgse	144	1	This	this	DT
cord-005603-kjcbbgse	144	2	question	question	NN
cord-005603-kjcbbgse	144	3	was	be	VBD
cord-005603-kjcbbgse	144	4	specifically	specifically	RB
cord-005603-kjcbbgse	144	5	addressed	address	VBN
cord-005603-kjcbbgse	144	6	in	in	IN
cord-005603-kjcbbgse	144	7	the	the	DT
cord-005603-kjcbbgse	144	8	French	french	JJ
cord-005603-kjcbbgse	144	9	multicenter	multicenter	JJ
cord-005603-kjcbbgse	144	10	study	study	NN
cord-005603-kjcbbgse	144	11	of	of	IN
cord-005603-kjcbbgse	144	12	832	832	CD
cord-005603-kjcbbgse	144	13	patients	patient	NNS
cord-005603-kjcbbgse	144	14	with	with	IN
cord-005603-kjcbbgse	144	15	bacteraemia	bacteraemia	NNP
cord-005603-kjcbbgse	144	16	[	[	-LRB-
cord-005603-kjcbbgse	144	17	5	5	CD
cord-005603-kjcbbgse	144	18	]	]	-RRB-
cord-005603-kjcbbgse	144	19	.	.	.
cord-005603-kjcbbgse	145	1	By	by	IN
cord-005603-kjcbbgse	145	2	Cox	Cox	NNP
cord-005603-kjcbbgse	145	3	regression	regression	NN
cord-005603-kjcbbgse	145	4	analysis	analysis	NN
cord-005603-kjcbbgse	145	5	,	,	,
cord-005603-kjcbbgse	145	6	independent	independent	JJ
cord-005603-kjcbbgse	145	7	factors	factor	NNS
cord-005603-kjcbbgse	145	8	associated	associate	VBN
cord-005603-kjcbbgse	145	9	with	with	IN
cord-005603-kjcbbgse	145	10	severe	severe	JJ
cord-005603-kjcbbgse	145	11	sepsis	sepsis	NN
cord-005603-kjcbbgse	145	12	during	during	IN
cord-005603-kjcbbgse	145	13	bacteraemia	bacteraemia	NNP
cord-005603-kjcbbgse	145	14	were	be	VBD
cord-005603-kjcbbgse	145	15	increasing	increase	VBG
cord-005603-kjcbbgse	145	16	age	age	NN
cord-005603-kjcbbgse	145	17	(	(	-LRB-
cord-005603-kjcbbgse	145	18	>	>	NFP
cord-005603-kjcbbgse	145	19	50	50	CD
cord-005603-kjcbbgse	145	20	years	year	NNS
cord-005603-kjcbbgse	145	21	)	)	-RRB-
cord-005603-kjcbbgse	145	22	,	,	,
cord-005603-kjcbbgse	145	23	sources	source	NNS
cord-005603-kjcbbgse	145	24	other	other	JJ
cord-005603-kjcbbgse	145	25	than	than	IN
cord-005603-kjcbbgse	145	26	the	the	DT
cord-005603-kjcbbgse	145	27	urinary	urinary	JJ
cord-005603-kjcbbgse	145	28	tract	tract	NN
cord-005603-kjcbbgse	145	29	,	,	,
cord-005603-kjcbbgse	145	30	an	an	DT
cord-005603-kjcbbgse	145	31	intravascular	intravascular	JJ
cord-005603-kjcbbgse	145	32	catheter	catheter	NN
cord-005603-kjcbbgse	145	33	,	,	,
cord-005603-kjcbbgse	145	34	or	or	CC
cord-005603-kjcbbgse	145	35	primary	primary	JJ
cord-005603-kjcbbgse	145	36	bacteraemia	bacteraemia	NN
cord-005603-kjcbbgse	145	37	.	.	.
cord-005603-kjcbbgse	146	1	Organisms	organism	NNS
cord-005603-kjcbbgse	146	2	involved	involve	VBN
cord-005603-kjcbbgse	146	3	were	be	VBD
cord-005603-kjcbbgse	146	4	not	not	RB
cord-005603-kjcbbgse	146	5	associated	associate	VBN
cord-005603-kjcbbgse	146	6	with	with	IN
cord-005603-kjcbbgse	146	7	the	the	DT
cord-005603-kjcbbgse	146	8	occurrence	occurrence	NN
cord-005603-kjcbbgse	146	9	of	of	IN
cord-005603-kjcbbgse	146	10	severe	severe	JJ
cord-005603-kjcbbgse	146	11	sepsis	sepsis	NN
cord-005603-kjcbbgse	146	12	,	,	,
cord-005603-kjcbbgse	146	13	nor	nor	CC
cord-005603-kjcbbgse	146	14	was	be	VBD
cord-005603-kjcbbgse	146	15	the	the	DT
cord-005603-kjcbbgse	146	16	severity	severity	NN
cord-005603-kjcbbgse	146	17	of	of	IN
cord-005603-kjcbbgse	146	18	the	the	DT
cord-005603-kjcbbgse	146	19	underlying	underlie	VBG
cord-005603-kjcbbgse	146	20	disease	disease	NN
cord-005603-kjcbbgse	146	21	.	.	.
cord-005603-kjcbbgse	147	1	In	in	IN
cord-005603-kjcbbgse	147	2	another	another	DT
cord-005603-kjcbbgse	147	3	retrospective	retrospective	JJ
cord-005603-kjcbbgse	147	4	study	study	NN
cord-005603-kjcbbgse	147	5	of	of	IN
cord-005603-kjcbbgse	147	6	1505	1505	CD
cord-005603-kjcbbgse	147	7	patients	patient	NNS
cord-005603-kjcbbgse	147	8	that	that	WDT
cord-005603-kjcbbgse	147	9	had	have	VBD
cord-005603-kjcbbgse	147	10	been	be	VBN
cord-005603-kjcbbgse	147	11	included	include	VBN
cord-005603-kjcbbgse	147	12	in	in	IN
cord-005603-kjcbbgse	147	13	the	the	DT
cord-005603-kjcbbgse	147	14	VA	VA	NNP
cord-005603-kjcbbgse	147	15	corticosteroids	corticosteroid	NNS
cord-005603-kjcbbgse	147	16	trials	trial	NNS
cord-005603-kjcbbgse	147	17	[	[	-LRB-
cord-005603-kjcbbgse	147	18	16	16	CD
cord-005603-kjcbbgse	147	19	]	]	-RRB-
cord-005603-kjcbbgse	147	20	(	(	-LRB-
cord-005603-kjcbbgse	147	21	of	of	IN
cord-005603-kjcbbgse	147	22	whom	whom	WP
cord-005603-kjcbbgse	147	23	40	40	CD
cord-005603-kjcbbgse	147	24	%	%	NN
cord-005603-kjcbbgse	147	25	had	have	VBD
cord-005603-kjcbbgse	147	26	uncomplicated	uncomplicated	JJ
cord-005603-kjcbbgse	147	27	sepsis	sepsis	NN
cord-005603-kjcbbgse	147	28	,	,	,
cord-005603-kjcbbgse	147	29	45	45	CD
cord-005603-kjcbbgse	147	30	%	%	NN
cord-005603-kjcbbgse	147	31	met	meet	VBD
cord-005603-kjcbbgse	147	32	criteria	criterion	NNS
cord-005603-kjcbbgse	147	33	for	for	IN
cord-005603-kjcbbgse	147	34	severe	severe	JJ
cord-005603-kjcbbgse	147	35	sepsis	sepsis	NN
cord-005603-kjcbbgse	147	36	and	and	CC
cord-005603-kjcbbgse	147	37	15	15	CD
cord-005603-kjcbbgse	147	38	%	%	NN
cord-005603-kjcbbgse	147	39	for	for	IN
cord-005603-kjcbbgse	147	40	septic	septic	JJ
cord-005603-kjcbbgse	147	41	shock	shock	NN
cord-005603-kjcbbgse	147	42	)	)	-RRB-
cord-005603-kjcbbgse	147	43	,	,	,
cord-005603-kjcbbgse	147	44	independent	independent	JJ
cord-005603-kjcbbgse	147	45	risk	risk	NN
cord-005603-kjcbbgse	147	46	factors	factor	NNS
cord-005603-kjcbbgse	147	47	for	for	IN
cord-005603-kjcbbgse	147	48	the	the	DT
cord-005603-kjcbbgse	147	49	development	development	NN
cord-005603-kjcbbgse	147	50	of	of	IN
cord-005603-kjcbbgse	147	51	severe	severe	JJ
cord-005603-kjcbbgse	147	52	sepsis	sepsis	NN
cord-005603-kjcbbgse	147	53	or	or	CC
cord-005603-kjcbbgse	147	54	shock	shock	NN
cord-005603-kjcbbgse	147	55	were	be	VBD
cord-005603-kjcbbgse	147	56	age	age	NN
cord-005603-kjcbbgse	147	57	,	,	,
cord-005603-kjcbbgse	147	58	gastro	gastro	JJ
cord-005603-kjcbbgse	147	59	-	-	JJ
cord-005603-kjcbbgse	147	60	intestinal	intestinal	JJ
cord-005603-kjcbbgse	147	61	tract	tract	NN
cord-005603-kjcbbgse	147	62	disease	disease	NN
cord-005603-kjcbbgse	147	63	,	,	,
cord-005603-kjcbbgse	147	64	liver	liver	NN
cord-005603-kjcbbgse	147	65	disease	disease	NN
cord-005603-kjcbbgse	147	66	,	,	,
cord-005603-kjcbbgse	147	67	haematological	haematological	JJ
cord-005603-kjcbbgse	147	68	disorders	disorder	NNS
cord-005603-kjcbbgse	147	69	,	,	,
cord-005603-kjcbbgse	147	70	spinal	spinal	JJ
cord-005603-kjcbbgse	147	71	cord	cord	NN
cord-005603-kjcbbgse	147	72	injury	injury	NN
cord-005603-kjcbbgse	147	73	,	,	,
cord-005603-kjcbbgse	147	74	and	and	CC
cord-005603-kjcbbgse	147	75	drug	drug	NN
cord-005603-kjcbbgse	147	76	abuse	abuse	NN
cord-005603-kjcbbgse	147	77	.	.	.
cord-005603-kjcbbgse	148	1	As	as	IN
cord-005603-kjcbbgse	148	2	already	already	RB
cord-005603-kjcbbgse	148	3	mentioned	mention	VBN
cord-005603-kjcbbgse	148	4	,	,	,
cord-005603-kjcbbgse	148	5	only	only	RB
cord-005603-kjcbbgse	148	6	a	a	DT
cord-005603-kjcbbgse	148	7	limited	limited	JJ
cord-005603-kjcbbgse	148	8	fraction	fraction	NN
cord-005603-kjcbbgse	148	9	of	of	IN
cord-005603-kjcbbgse	148	10	patients	patient	NNS
cord-005603-kjcbbgse	148	11	presenting	present	VBG
cord-005603-kjcbbgse	148	12	with	with	IN
cord-005603-kjcbbgse	148	13	one	one	CD
cord-005603-kjcbbgse	148	14	of	of	IN
cord-005603-kjcbbgse	148	15	the	the	DT
cord-005603-kjcbbgse	148	16	septic	septic	JJ
cord-005603-kjcbbgse	148	17	syndromes	syndrome	NNS
cord-005603-kjcbbgse	148	18	have	have	VBP
cord-005603-kjcbbgse	148	19	microbiologically	microbiologically	RB
cord-005603-kjcbbgse	148	20	documented	document	VBN
cord-005603-kjcbbgse	148	21	infection	infection	NN
cord-005603-kjcbbgse	148	22	.	.	.
cord-005603-kjcbbgse	149	1	In	in	IN
cord-005603-kjcbbgse	149	2	patients	patient	NNS
cord-005603-kjcbbgse	149	3	meeting	meet	VBG
cord-005603-kjcbbgse	149	4	criteria	criterion	NNS
cord-005603-kjcbbgse	149	5	for	for	IN
cord-005603-kjcbbgse	149	6	SIRS	SIRS	NNP
cord-005603-kjcbbgse	149	7	,	,	,
cord-005603-kjcbbgse	149	8	only	only	RB
cord-005603-kjcbbgse	149	9	42	42	CD
cord-005603-kjcbbgse	149	10	%	%	NN
cord-005603-kjcbbgse	149	11	were	be	VBD
cord-005603-kjcbbgse	149	12	found	find	VBN
cord-005603-kjcbbgse	149	13	by	by	IN
cord-005603-kjcbbgse	149	14	Rangel	Rangel	NNP
cord-005603-kjcbbgse	149	15	-	-	HYPH
cord-005603-kjcbbgse	149	16	Fausto	Fausto	NNP
cord-005603-kjcbbgse	149	17	et	et	NNP
cord-005603-kjcbbgse	149	18	al	al	NNP
cord-005603-kjcbbgse	149	19	.	.	NNP
cord-005603-kjcbbgse	149	20	,	,	,
cord-005603-kjcbbgse	149	21	to	to	TO
cord-005603-kjcbbgse	149	22	have	have	VB
cord-005603-kjcbbgse	149	23	documented	document	VBN
cord-005603-kjcbbgse	149	24	infection	infection	NN
cord-005603-kjcbbgse	149	25	(	(	-LRB-
cord-005603-kjcbbgse	149	26	i.	i.	NNP
cord-005603-kjcbbgse	149	27	e.	e.	NNP
cord-005603-kjcbbgse	149	28	,	,	,
cord-005603-kjcbbgse	149	29	sepsis	sepsis	NN
cord-005603-kjcbbgse	149	30	)	)	-RRB-
cord-005603-kjcbbgse	149	31	,	,	,
cord-005603-kjcbbgse	149	32	and	and	CC
cord-005603-kjcbbgse	149	33	58	58	CD
cord-005603-kjcbbgse	149	34	%	%	NN
cord-005603-kjcbbgse	149	35	had	have	VBD
cord-005603-kjcbbgse	149	36	culture	culture	NN
cord-005603-kjcbbgse	149	37	-	-	HYPH
cord-005603-kjcbbgse	149	38	negative	negative	JJ
cord-005603-kjcbbgse	149	39	,	,	,
cord-005603-kjcbbgse	149	40	but	but	CC
cord-005603-kjcbbgse	149	41	clinically	clinically	RB
cord-005603-kjcbbgse	149	42	documented	document	VBN
cord-005603-kjcbbgse	149	43	,	,	,
cord-005603-kjcbbgse	149	44	infection	infection	NN
cord-005603-kjcbbgse	149	45	;	;	:
cord-005603-kjcbbgse	149	46	the	the	DT
cord-005603-kjcbbgse	149	47	proportion	proportion	NN
cord-005603-kjcbbgse	149	48	of	of	IN
cord-005603-kjcbbgse	149	49	documented	document	VBN
cord-005603-kjcbbgse	149	50	infection	infection	NN
cord-005603-kjcbbgse	149	51	rose	rise	VBD
cord-005603-kjcbbgse	149	52	to	to	IN
cord-005603-kjcbbgse	149	53	only	only	RB
cord-005603-kjcbbgse	149	54	47	47	CD
cord-005603-kjcbbgse	149	55	%	%	NN
cord-005603-kjcbbgse	149	56	in	in	IN
cord-005603-kjcbbgse	149	57	patients	patient	NNS
cord-005603-kjcbbgse	149	58	with	with	IN
cord-005603-kjcbbgse	149	59	severe	severe	JJ
cord-005603-kjcbbgse	149	60	sepsis	sepsis	NN
cord-005603-kjcbbgse	149	61	,	,	,
cord-005603-kjcbbgse	149	62	and	and	CC
cord-005603-kjcbbgse	149	63	to	to	IN
cord-005603-kjcbbgse	149	64	57	57	CD
cord-005603-kjcbbgse	149	65	%	%	NN
cord-005603-kjcbbgse	149	66	in	in	IN
cord-005603-kjcbbgse	149	67	patients	patient	NNS
cord-005603-kjcbbgse	149	68	with	with	IN
cord-005603-kjcbbgse	149	69	septic	septic	JJ
cord-005603-kjcbbgse	149	70	shock	shock	NN
cord-005603-kjcbbgse	149	71	[	[	-LRB-
cord-005603-kjcbbgse	149	72	6	6	CD
cord-005603-kjcbbgse	149	73	]	]	-RRB-
cord-005603-kjcbbgse	149	74	.	.	.
cord-005603-kjcbbgse	150	1	Higher	high	JJR
cord-005603-kjcbbgse	150	2	rates	rate	NNS
cord-005603-kjcbbgse	150	3	of	of	IN
cord-005603-kjcbbgse	150	4	infection	infection	NN
cord-005603-kjcbbgse	150	5	were	be	VBD
cord-005603-kjcbbgse	150	6	similarly	similarly	RB
cord-005603-kjcbbgse	150	7	found	find	VBN
cord-005603-kjcbbgse	150	8	in	in	IN
cord-005603-kjcbbgse	150	9	the	the	DT
cord-005603-kjcbbgse	150	10	more	more	RBR
cord-005603-kjcbbgse	150	11	severe	severe	JJ
cord-005603-kjcbbgse	150	12	forms	form	NNS
cord-005603-kjcbbgse	150	13	of	of	IN
cord-005603-kjcbbgse	150	14	septic	septic	JJ
cord-005603-kjcbbgse	150	15	syndromes	syndrome	NNS
cord-005603-kjcbbgse	150	16	in	in	IN
cord-005603-kjcbbgse	150	17	other	other	JJ
cord-005603-kjcbbgse	150	18	studies	study	NNS
cord-005603-kjcbbgse	150	19	:	:	:
cord-005603-kjcbbgse	150	20	clinically	clinically	RB
cord-005603-kjcbbgse	150	21	or	or	CC
cord-005603-kjcbbgse	150	22	microbiologically	microbiologically	RB
cord-005603-kjcbbgse	150	23	documented	document	VBN
cord-005603-kjcbbgse	150	24	infection	infection	NN
cord-005603-kjcbbgse	150	25	was	be	VBD
cord-005603-kjcbbgse	150	26	recorded	record	VBN
cord-005603-kjcbbgse	150	27	in	in	IN
cord-005603-kjcbbgse	150	28	92	92	CD
cord-005603-kjcbbgse	150	29	%	%	NN
cord-005603-kjcbbgse	150	30	of	of	IN
cord-005603-kjcbbgse	150	31	episodes	episode	NNS
cord-005603-kjcbbgse	150	32	in	in	IN
cord-005603-kjcbbgse	150	33	patients	patient	NNS
cord-005603-kjcbbgse	150	34	meeting	meet	VBG
cord-005603-kjcbbgse	150	35	clinical	clinical	JJ
cord-005603-kjcbbgse	150	36	criteria	criterion	NNS
cord-005603-kjcbbgse	150	37	for	for	IN
cord-005603-kjcbbgse	150	38	severe	severe	JJ
cord-005603-kjcbbgse	150	39	sepsis	sepsis	NN
cord-005603-kjcbbgse	150	40	by	by	IN
cord-005603-kjcbbgse	150	41	Sands	Sands	NNPS
cord-005603-kjcbbgse	150	42	et	et	NNP
cord-005603-kjcbbgse	150	43	al	al	NNP
cord-005603-kjcbbgse	150	44	.	.	.
cord-005603-kjcbbgse	151	1	[	[	-LRB-
cord-005603-kjcbbgse	151	2	8	8	CD
cord-005603-kjcbbgse	151	3	]	]	-RRB-
cord-005603-kjcbbgse	151	4	and	and	CC
cord-005603-kjcbbgse	151	5	in	in	IN
cord-005603-kjcbbgse	151	6	95	95	CD
cord-005603-kjcbbgse	151	7	%	%	NN
cord-005603-kjcbbgse	151	8	of	of	IN
cord-005603-kjcbbgse	151	9	episodes	episode	NNS
cord-005603-kjcbbgse	151	10	recorded	record	VBN
cord-005603-kjcbbgse	151	11	by	by	IN
cord-005603-kjcbbgse	151	12	Brun	Brun	NNP
cord-005603-kjcbbgse	151	13	-	-	HYPH
cord-005603-kjcbbgse	151	14	Buisson	Buisson	NNP
cord-005603-kjcbbgse	151	15	et	et	FW
cord-005603-kjcbbgse	151	16	al	al	NNP
cord-005603-kjcbbgse	151	17	.	.	.
cord-005603-kjcbbgse	152	1	[	[	-LRB-
cord-005603-kjcbbgse	152	2	13	13	CD
cord-005603-kjcbbgse	152	3	]	]	-RRB-
cord-005603-kjcbbgse	152	4	;	;	:
cord-005603-kjcbbgse	152	5	in	in	IN
cord-005603-kjcbbgse	152	6	these	these	DT
cord-005603-kjcbbgse	152	7	two	two	CD
cord-005603-kjcbbgse	152	8	studies	study	NNS
cord-005603-kjcbbgse	152	9	,	,	,
cord-005603-kjcbbgse	152	10	70	70	CD
cord-005603-kjcbbgse	152	11	%	%	NN
cord-005603-kjcbbgse	152	12	and	and	CC
cord-005603-kjcbbgse	152	13	71	71	CD
cord-005603-kjcbbgse	152	14	%	%	NN
cord-005603-kjcbbgse	152	15	of	of	IN
cord-005603-kjcbbgse	152	16	patients	patient	NNS
cord-005603-kjcbbgse	152	17	had	have	VBD
cord-005603-kjcbbgse	152	18	microbiologically	microbiologically	RB
cord-005603-kjcbbgse	152	19	documented	document	VBN
cord-005603-kjcbbgse	152	20	infection	infection	NN
cord-005603-kjcbbgse	152	21	,	,	,
cord-005603-kjcbbgse	152	22	and	and	CC
cord-005603-kjcbbgse	152	23	30	30	CD
cord-005603-kjcbbgse	152	24	%	%	NN
cord-005603-kjcbbgse	152	25	and	and	CC
cord-005603-kjcbbgse	152	26	29	29	CD
cord-005603-kjcbbgse	152	27	%	%	NN
cord-005603-kjcbbgse	152	28	had	have	VBD
cord-005603-kjcbbgse	152	29	clinically	clinically	RB
cord-005603-kjcbbgse	152	30	documented	document	VBN
cord-005603-kjcbbgse	152	31	infection	infection	NN
cord-005603-kjcbbgse	152	32	,	,	,
cord-005603-kjcbbgse	152	33	respectively	respectively	RB
cord-005603-kjcbbgse	152	34	.	.	.
cord-005603-kjcbbgse	153	1	Therefore	therefore	RB
cord-005603-kjcbbgse	153	2	,	,	,
cord-005603-kjcbbgse	153	3	only	only	RB
cord-005603-kjcbbgse	153	4	a	a	DT
cord-005603-kjcbbgse	153	5	small	small	JJ
cord-005603-kjcbbgse	153	6	fraction	fraction	NN
cord-005603-kjcbbgse	153	7	of	of	IN
cord-005603-kjcbbgse	153	8	patients	patient	NNS
cord-005603-kjcbbgse	153	9	presenting	present	VBG
cord-005603-kjcbbgse	153	10	with	with	IN
cord-005603-kjcbbgse	153	11	clinically	clinically	RB
cord-005603-kjcbbgse	153	12	suspected	suspect	VBN
cord-005603-kjcbbgse	153	13	severe	severe	JJ
cord-005603-kjcbbgse	153	14	sepsis	sepsis	NN
cord-005603-kjcbbgse	153	15	(	(	-LRB-
cord-005603-kjcbbgse	153	16	5	5	CD
cord-005603-kjcbbgse	153	17	%	%	NN
cord-005603-kjcbbgse	153	18	±10	±10	NNP
cord-005603-kjcbbgse	153	19	%	%	NN
cord-005603-kjcbbgse	153	20	)	)	-RRB-
cord-005603-kjcbbgse	153	21	had	have	VBD
cord-005603-kjcbbgse	153	22	no	no	DT
cord-005603-kjcbbgse	153	23	infection	infection	NN
cord-005603-kjcbbgse	153	24	clinically	clinically	RB
cord-005603-kjcbbgse	153	25	or	or	CC
cord-005603-kjcbbgse	153	26	microbiologically	microbiologically	RB
cord-005603-kjcbbgse	153	27	documented	document	VBN
cord-005603-kjcbbgse	153	28	.	.	.
cord-005603-kjcbbgse	154	1	The	the	DT
cord-005603-kjcbbgse	154	2	four	four	CD
cord-005603-kjcbbgse	154	3	major	major	JJ
cord-005603-kjcbbgse	154	4	sources	source	NNS
cord-005603-kjcbbgse	154	5	of	of	IN
cord-005603-kjcbbgse	154	6	infection	infection	NN
cord-005603-kjcbbgse	154	7	in	in	IN
cord-005603-kjcbbgse	154	8	patients	patient	NNS
cord-005603-kjcbbgse	154	9	with	with	IN
cord-005603-kjcbbgse	154	10	severe	severe	JJ
cord-005603-kjcbbgse	154	11	sepsis	sepsis	NN
cord-005603-kjcbbgse	154	12	,	,	,
cord-005603-kjcbbgse	154	13	in	in	IN
cord-005603-kjcbbgse	154	14	descending	descend	VBG
cord-005603-kjcbbgse	154	15	order	order	NN
cord-005603-kjcbbgse	154	16	,	,	,
cord-005603-kjcbbgse	154	17	are	be	VBP
cord-005603-kjcbbgse	154	18	the	the	DT
cord-005603-kjcbbgse	154	19	respiratory	respiratory	JJ
cord-005603-kjcbbgse	154	20	tract	tract	NN
cord-005603-kjcbbgse	154	21	,	,	,
cord-005603-kjcbbgse	154	22	the	the	DT
cord-005603-kjcbbgse	154	23	abdomen	abdomen	NN
cord-005603-kjcbbgse	154	24	,	,	,
cord-005603-kjcbbgse	154	25	the	the	DT
cord-005603-kjcbbgse	154	26	urinary	urinary	JJ
cord-005603-kjcbbgse	154	27	tract	tract	NN
cord-005603-kjcbbgse	154	28	,	,	,
cord-005603-kjcbbgse	154	29	and	and	CC
cord-005603-kjcbbgse	154	30	primary	primary	JJ
cord-005603-kjcbbgse	154	31	bacteraemia	bacteraemia	NN
cord-005603-kjcbbgse	154	32	[	[	-LRB-
cord-005603-kjcbbgse	154	33	8	8	CD
cord-005603-kjcbbgse	154	34	,	,	,
cord-005603-kjcbbgse	154	35	13	13	CD
cord-005603-kjcbbgse	154	36	]	]	-RRB-
cord-005603-kjcbbgse	154	37	;	;	:
cord-005603-kjcbbgse	154	38	these	these	DT
cord-005603-kjcbbgse	154	39	sources	source	NNS
cord-005603-kjcbbgse	154	40	account	account	VBP
cord-005603-kjcbbgse	154	41	for	for	IN
cord-005603-kjcbbgse	154	42	>	>	XX
cord-005603-kjcbbgse	154	43	75	75	CD
cord-005603-kjcbbgse	154	44	%	%	NN
cord-005603-kjcbbgse	154	45	of	of	IN
cord-005603-kjcbbgse	154	46	cases	case	NNS
cord-005603-kjcbbgse	154	47	of	of	IN
cord-005603-kjcbbgse	154	48	severe	severe	JJ
cord-005603-kjcbbgse	154	49	sepsis	sepsis	NN
cord-005603-kjcbbgse	155	1	(	(	-LRB-
cord-005603-kjcbbgse	155	2	Table	table	NN
cord-005603-kjcbbgse	155	3	3	3	CD
cord-005603-kjcbbgse	155	4	a	a	LS
cord-005603-kjcbbgse	155	5	)	)	-RRB-
cord-005603-kjcbbgse	155	6	.	.	.
cord-005603-kjcbbgse	156	1	This	this	DT
cord-005603-kjcbbgse	156	2	distribution	distribution	NN
cord-005603-kjcbbgse	156	3	differs	differ	VBZ
cord-005603-kjcbbgse	156	4	somewhat	somewhat	RB
cord-005603-kjcbbgse	156	5	from	from	IN
cord-005603-kjcbbgse	156	6	that	that	DT
cord-005603-kjcbbgse	156	7	observed	observe	VBN
cord-005603-kjcbbgse	156	8	in	in	IN
cord-005603-kjcbbgse	156	9	patients	patient	NNS
cord-005603-kjcbbgse	156	10	with	with	IN
cord-005603-kjcbbgse	156	11	bacteraemic	bacteraemic	NNP
cord-005603-kjcbbgse	156	12	sepsis	sepsis	NN
cord-005603-kjcbbgse	156	13	,	,	,
cord-005603-kjcbbgse	156	14	where	where	WRB
cord-005603-kjcbbgse	156	15	the	the	DT
cord-005603-kjcbbgse	156	16	urinary	urinary	JJ
cord-005603-kjcbbgse	156	17	tract	tract	NN
cord-005603-kjcbbgse	156	18	is	be	VBZ
cord-005603-kjcbbgse	156	19	the	the	DT
cord-005603-kjcbbgse	156	20	major	major	JJ
cord-005603-kjcbbgse	156	21	source	source	NN
cord-005603-kjcbbgse	156	22	of	of	IN
cord-005603-kjcbbgse	156	23	infection	infection	NN
cord-005603-kjcbbgse	156	24	(	(	-LRB-
cord-005603-kjcbbgse	156	25	Table	table	NN
cord-005603-kjcbbgse	156	26	3	3	CD
cord-005603-kjcbbgse	156	27	b	b	NN
cord-005603-kjcbbgse	156	28	)	)	-RRB-
cord-005603-kjcbbgse	156	29	,	,	,
cord-005603-kjcbbgse	156	30	reflecting	reflect	VBG
cord-005603-kjcbbgse	156	31	the	the	DT
cord-005603-kjcbbgse	156	32	lower	low	JJR
cord-005603-kjcbbgse	156	33	risk	risk	NN
cord-005603-kjcbbgse	156	34	associated	associate	VBN
cord-005603-kjcbbgse	156	35	with	with	IN
cord-005603-kjcbbgse	156	36	this	this	DT
cord-005603-kjcbbgse	156	37	source	source	NN
cord-005603-kjcbbgse	156	38	in	in	IN
cord-005603-kjcbbgse	156	39	causing	cause	VBG
cord-005603-kjcbbgse	156	40	severe	severe	JJ
cord-005603-kjcbbgse	156	41	sepsis	sepsis	NN
cord-005603-kjcbbgse	156	42	,	,	,
cord-005603-kjcbbgse	156	43	as	as	IN
cord-005603-kjcbbgse	156	44	already	already	RB
cord-005603-kjcbbgse	156	45	mentioned	mention	VBN
cord-005603-kjcbbgse	156	46	.	.	.
cord-005603-kjcbbgse	157	1	Of	of	IN
cord-005603-kjcbbgse	157	2	note	note	NN
cord-005603-kjcbbgse	157	3	,	,	,
cord-005603-kjcbbgse	157	4	there	there	EX
cord-005603-kjcbbgse	157	5	is	be	VBZ
cord-005603-kjcbbgse	157	6	no	no	DT
cord-005603-kjcbbgse	157	7	major	major	JJ
cord-005603-kjcbbgse	157	8	difference	difference	NN
cord-005603-kjcbbgse	157	9	in	in	IN
cord-005603-kjcbbgse	157	10	the	the	DT
cord-005603-kjcbbgse	157	11	distribution	distribution	NN
cord-005603-kjcbbgse	157	12	of	of	IN
cord-005603-kjcbbgse	157	13	sources	source	NNS
cord-005603-kjcbbgse	157	14	of	of	IN
cord-005603-kjcbbgse	157	15	infection	infection	NN
cord-005603-kjcbbgse	157	16	when	when	WRB
cord-005603-kjcbbgse	157	17	one	one	PRP
cord-005603-kjcbbgse	157	18	compares	compare	VBZ
cord-005603-kjcbbgse	157	19	microbiologically	microbiologically	RB
cord-005603-kjcbbgse	157	20	documented	document	VBD
cord-005603-kjcbbgse	157	21	cases	case	NNS
cord-005603-kjcbbgse	157	22	to	to	TO
cord-005603-kjcbbgse	157	23	clinically	clinically	RB
cord-005603-kjcbbgse	157	24	documented	document	VBN
cord-005603-kjcbbgse	157	25	cases	case	NNS
cord-005603-kjcbbgse	157	26	,	,	,
cord-005603-kjcbbgse	157	27	except	except	IN
cord-005603-kjcbbgse	157	28	for	for	IN
cord-005603-kjcbbgse	157	29	a	a	DT
cord-005603-kjcbbgse	157	30	higher	high	JJR
cord-005603-kjcbbgse	157	31	proportion	proportion	NN
cord-005603-kjcbbgse	157	32	of	of	IN
cord-005603-kjcbbgse	157	33	urinary	urinary	JJ
cord-005603-kjcbbgse	157	34	tract	tract	NN
cord-005603-kjcbbgse	157	35	infection	infection	NN
cord-005603-kjcbbgse	157	36	and	and	CC
cord-005603-kjcbbgse	157	37	catheter	catheter	NN
cord-005603-kjcbbgse	157	38	infection	infection	NN
cord-005603-kjcbbgse	157	39	in	in	IN
cord-005603-kjcbbgse	157	40	the	the	DT
cord-005603-kjcbbgse	157	41	former	former	JJ
cord-005603-kjcbbgse	157	42	group	group	NN
cord-005603-kjcbbgse	157	43	.	.	.
cord-005603-kjcbbgse	158	1	Microbial	microbial	JJ
cord-005603-kjcbbgse	158	2	epidemiology	epidemiology	NN
cord-005603-kjcbbgse	158	3	of	of	IN
cord-005603-kjcbbgse	158	4	sepsis	sepsis	NN
cord-005603-kjcbbgse	158	5	,	,	,
cord-005603-kjcbbgse	158	6	severe	severe	JJ
cord-005603-kjcbbgse	158	7	sepsis	sepsis	NN
cord-005603-kjcbbgse	158	8	or	or	CC
cord-005603-kjcbbgse	158	9	shock	shock	NN
cord-005603-kjcbbgse	159	1	The	the	DT
cord-005603-kjcbbgse	159	2	microbiological	microbiological	JJ
cord-005603-kjcbbgse	159	3	features	feature	NNS
cord-005603-kjcbbgse	159	4	of	of	IN
cord-005603-kjcbbgse	159	5	the	the	DT
cord-005603-kjcbbgse	159	6	septic	septic	JJ
cord-005603-kjcbbgse	159	7	syndromes	syndrome	NNS
cord-005603-kjcbbgse	159	8	may	may	MD
cord-005603-kjcbbgse	159	9	depend	depend	VB
cord-005603-kjcbbgse	159	10	in	in	IN
cord-005603-kjcbbgse	159	11	part	part	NN
cord-005603-kjcbbgse	159	12	on	on	IN
cord-005603-kjcbbgse	159	13	the	the	DT
cord-005603-kjcbbgse	159	14	population	population	NN
cord-005603-kjcbbgse	159	15	studied	study	VBD
cord-005603-kjcbbgse	159	16	and	and	CC
cord-005603-kjcbbgse	159	17	setting	set	VBG
cord-005603-kjcbbgse	159	18	.	.	.
cord-005603-kjcbbgse	160	1	Bacteraemia	Bacteraemia	NNP
cord-005603-kjcbbgse	160	2	may	may	MD
cord-005603-kjcbbgse	160	3	be	be	VB
cord-005603-kjcbbgse	160	4	taken	take	VBN
cord-005603-kjcbbgse	160	5	as	as	IN
cord-005603-kjcbbgse	160	6	the	the	DT
cord-005603-kjcbbgse	160	7	reference	reference	NN
cord-005603-kjcbbgse	160	8	syndrome	syndrome	NN
cord-005603-kjcbbgse	160	9	for	for	IN
cord-005603-kjcbbgse	160	10	looking	look	VBG
cord-005603-kjcbbgse	160	11	at	at	IN
cord-005603-kjcbbgse	160	12	microbial	microbial	JJ
cord-005603-kjcbbgse	160	13	aetiologies	aetiology	NNS
cord-005603-kjcbbgse	160	14	of	of	IN
cord-005603-kjcbbgse	160	15	sepsis	sepsis	NN
cord-005603-kjcbbgse	160	16	.	.	.
cord-005603-kjcbbgse	161	1	It	-PRON-	PRP
cord-005603-kjcbbgse	161	2	should	should	MD
cord-005603-kjcbbgse	161	3	be	be	VB
cord-005603-kjcbbgse	161	4	recalled	recall	VBN
cord-005603-kjcbbgse	161	5	that	that	IN
cord-005603-kjcbbgse	161	6	major	major	JJ
cord-005603-kjcbbgse	161	7	changes	change	NNS
cord-005603-kjcbbgse	161	8	have	have	VBP
cord-005603-kjcbbgse	161	9	occurred	occur	VBN
cord-005603-kjcbbgse	161	10	in	in	IN
cord-005603-kjcbbgse	161	11	the	the	DT
cord-005603-kjcbbgse	161	12	past	past	JJ
cord-005603-kjcbbgse	161	13	two	two	CD
cord-005603-kjcbbgse	161	14	decades	decade	NNS
cord-005603-kjcbbgse	161	15	in	in	IN
cord-005603-kjcbbgse	161	16	the	the	DT
cord-005603-kjcbbgse	161	17	epidemiology	epidemiology	NN
cord-005603-kjcbbgse	161	18	of	of	IN
cord-005603-kjcbbgse	161	19	bacteraemia	bacteraemia	NNP
cord-005603-kjcbbgse	161	20	.	.	.
cord-005603-kjcbbgse	162	1	These	these	DT
cord-005603-kjcbbgse	162	2	include	include	VBP
cord-005603-kjcbbgse	162	3	increasing	increase	VBG
cord-005603-kjcbbgse	162	4	rates	rate	NNS
cord-005603-kjcbbgse	162	5	overall	overall	RB
cord-005603-kjcbbgse	162	6	,	,	,
cord-005603-kjcbbgse	162	7	and	and	CC
cord-005603-kjcbbgse	162	8	a	a	DT
cord-005603-kjcbbgse	162	9	growing	grow	VBG
cord-005603-kjcbbgse	162	10	importance	importance	NN
cord-005603-kjcbbgse	162	11	of	of	IN
cord-005603-kjcbbgse	162	12	gram	gram	NN
cord-005603-kjcbbgse	162	13	-	-	HYPH
cord-005603-kjcbbgse	162	14	positive	positive	JJ
cord-005603-kjcbbgse	162	15	organisms	organism	NNS
cord-005603-kjcbbgse	162	16	over	over	IN
cord-005603-kjcbbgse	162	17	the	the	DT
cord-005603-kjcbbgse	162	18	years	year	NNS
cord-005603-kjcbbgse	162	19	,	,	,
cord-005603-kjcbbgse	162	20	especially	especially	RB
cord-005603-kjcbbgse	162	21	among	among	IN
cord-005603-kjcbbgse	162	22	nosocomial	nosocomial	JJ
cord-005603-kjcbbgse	162	23	episodes	episode	NNS
cord-005603-kjcbbgse	162	24	,	,	,
cord-005603-kjcbbgse	162	25	which	which	WDT
cord-005603-kjcbbgse	162	26	account	account	VBP
cord-005603-kjcbbgse	162	27	for	for	IN
cord-005603-kjcbbgse	162	28	most	most	JJS
cord-005603-kjcbbgse	162	29	of	of	IN
cord-005603-kjcbbgse	162	30	the	the	DT
cord-005603-kjcbbgse	162	31	recent	recent	JJ
cord-005603-kjcbbgse	162	32	increased	increase	VBN
cord-005603-kjcbbgse	162	33	rates	rate	NNS
cord-005603-kjcbbgse	162	34	[	[	-LRB-
cord-005603-kjcbbgse	162	35	4	4	CD
cord-005603-kjcbbgse	162	36	]	]	-RRB-
cord-005603-kjcbbgse	162	37	.	.	.
cord-005603-kjcbbgse	163	1	Much	much	JJ
cord-005603-kjcbbgse	163	2	of	of	IN
cord-005603-kjcbbgse	163	3	this	this	DT
cord-005603-kjcbbgse	163	4	increasing	increase	VBG
cord-005603-kjcbbgse	163	5	role	role	NN
cord-005603-kjcbbgse	163	6	of	of	IN
cord-005603-kjcbbgse	163	7	gram	gram	NN
cord-005603-kjcbbgse	163	8	-	-	HYPH
cord-005603-kjcbbgse	163	9	positive	positive	JJ
cord-005603-kjcbbgse	163	10	organisms	organism	NNS
cord-005603-kjcbbgse	163	11	is	be	VBZ
cord-005603-kjcbbgse	163	12	due	due	JJ
cord-005603-kjcbbgse	163	13	to	to	IN
cord-005603-kjcbbgse	163	14	catheter	catheter	NN
cord-005603-kjcbbgse	163	15	-	-	HYPH
cord-005603-kjcbbgse	163	16	related	relate	VBN
cord-005603-kjcbbgse	163	17	infections	infection	NNS
cord-005603-kjcbbgse	163	18	and	and	CC
cord-005603-kjcbbgse	163	19	primary	primary	JJ
cord-005603-kjcbbgse	163	20	bacteraemia	bacteraemia	NN
cord-005603-kjcbbgse	163	21	.	.	.
cord-005603-kjcbbgse	164	1	As	as	IN
cord-005603-kjcbbgse	164	2	a	a	DT
cord-005603-kjcbbgse	164	3	result	result	NN
cord-005603-kjcbbgse	164	4	,	,	,
cord-005603-kjcbbgse	164	5	gram	gram	NN
cord-005603-kjcbbgse	164	6	-	-	HYPH
cord-005603-kjcbbgse	164	7	positives	positive	NNS
cord-005603-kjcbbgse	164	8	now	now	RB
cord-005603-kjcbbgse	164	9	outweigh	outweigh	VBP
cord-005603-kjcbbgse	164	10	gramnegative	gramnegative	NN
cord-005603-kjcbbgse	164	11	among	among	IN
cord-005603-kjcbbgse	164	12	bacteraemic	bacteraemic	NNP
cord-005603-kjcbbgse	164	13	episodes	episode	NNS
cord-005603-kjcbbgse	164	14	(	(	-LRB-
cord-005603-kjcbbgse	164	15	55	55	CD
cord-005603-kjcbbgse	164	16	%	%	NN
cord-005603-kjcbbgse	164	17	vs	vs	IN
cord-005603-kjcbbgse	164	18	45	45	CD
cord-005603-kjcbbgse	164	19	%	%	NN
cord-005603-kjcbbgse	164	20	)	)	-RRB-
cord-005603-kjcbbgse	164	21	,	,	,
cord-005603-kjcbbgse	164	22	as	as	IN
cord-005603-kjcbbgse	164	23	shown	show	VBN
cord-005603-kjcbbgse	164	24	in	in	IN
cord-005603-kjcbbgse	164	25	the	the	DT
cord-005603-kjcbbgse	164	26	French	french	JJ
cord-005603-kjcbbgse	164	27	multicenter	multicenter	JJ
cord-005603-kjcbbgse	164	28	study	study	NN
cord-005603-kjcbbgse	164	29	(	(	-LRB-
cord-005603-kjcbbgse	164	30	Table	Table	NNP
cord-005603-kjcbbgse	164	31	4	4	CD
cord-005603-kjcbbgse	164	32	)	)	-RRB-
cord-005603-kjcbbgse	165	1	[	[	-LRB-
cord-005603-kjcbbgse	165	2	5	5	CD
cord-005603-kjcbbgse	165	3	]	]	-RRB-
cord-005603-kjcbbgse	165	4	.	.	.
cord-005603-kjcbbgse	166	1	In	in	IN
cord-005603-kjcbbgse	166	2	severe	severe	JJ
cord-005603-kjcbbgse	166	3	sepsis	sepsis	NN
cord-005603-kjcbbgse	166	4	,	,	,
cord-005603-kjcbbgse	166	5	however	however	RB
cord-005603-kjcbbgse	166	6	,	,	,
cord-005603-kjcbbgse	166	7	the	the	DT
cord-005603-kjcbbgse	166	8	proportion	proportion	NN
cord-005603-kjcbbgse	166	9	of	of	IN
cord-005603-kjcbbgse	166	10	grampositives	grampositive	NNS
cord-005603-kjcbbgse	166	11	and	and	CC
cord-005603-kjcbbgse	166	12	gram	gram	NN
cord-005603-kjcbbgse	166	13	-	-	HYPH
cord-005603-kjcbbgse	166	14	negatives	negative	NNS
cord-005603-kjcbbgse	166	15	appear	appear	VBP
cord-005603-kjcbbgse	166	16	similar	similar	JJ
cord-005603-kjcbbgse	166	17	,	,	,
cord-005603-kjcbbgse	166	18	reflecting	reflect	VBG
cord-005603-kjcbbgse	166	19	the	the	DT
cord-005603-kjcbbgse	166	20	lower	low	JJR
cord-005603-kjcbbgse	166	21	risk	risk	NN
cord-005603-kjcbbgse	166	22	of	of	IN
cord-005603-kjcbbgse	166	23	severe	severe	JJ
cord-005603-kjcbbgse	166	24	sepsis	sepsis	NN
cord-005603-kjcbbgse	166	25	associated	associate	VBN
cord-005603-kjcbbgse	166	26	with	with	IN
cord-005603-kjcbbgse	166	27	infection	infection	NN
cord-005603-kjcbbgse	166	28	caused	cause	VBN
cord-005603-kjcbbgse	166	29	by	by	IN
cord-005603-kjcbbgse	166	30	coagulase	coagulase	NN
cord-005603-kjcbbgse	166	31	-	-	HYPH
cord-005603-kjcbbgse	166	32	negative	negative	JJ
cord-005603-kjcbbgse	166	33	staphylococci	staphylococcus	NNS
cord-005603-kjcbbgse	166	34	[	[	-LRB-
cord-005603-kjcbbgse	166	35	13	13	CD
cord-005603-kjcbbgse	166	36	]	]	-RRB-
cord-005603-kjcbbgse	166	37	;	;	:
cord-005603-kjcbbgse	166	38	in	in	IN
cord-005603-kjcbbgse	166	39	non	non	JJ
cord-005603-kjcbbgse	166	40	-	-	JJ
cord-005603-kjcbbgse	166	41	bacteraemic	bacteraemic	JJ
cord-005603-kjcbbgse	166	42	severe	severe	JJ
cord-005603-kjcbbgse	166	43	sepsis	sepsis	NN
cord-005603-kjcbbgse	166	44	,	,	,
cord-005603-kjcbbgse	166	45	however	however	RB
cord-005603-kjcbbgse	166	46	,	,	,
cord-005603-kjcbbgse	166	47	gram	gram	NN
cord-005603-kjcbbgse	166	48	-	-	HYPH
cord-005603-kjcbbgse	166	49	negative	negative	JJ
cord-005603-kjcbbgse	166	50	organisms	organism	NNS
cord-005603-kjcbbgse	166	51	appear	appear	VBP
cord-005603-kjcbbgse	166	52	to	to	TO
cord-005603-kjcbbgse	166	53	predominate	predominate	VB
cord-005603-kjcbbgse	166	54	[	[	-LRB-
cord-005603-kjcbbgse	166	55	8	8	CD
cord-005603-kjcbbgse	166	56	]	]	-RRB-
cord-005603-kjcbbgse	166	57	.	.	.
cord-005603-kjcbbgse	167	1	Again	again	RB
cord-005603-kjcbbgse	167	2	,	,	,
cord-005603-kjcbbgse	167	3	there	there	EX
cord-005603-kjcbbgse	167	4	was	be	VBD
cord-005603-kjcbbgse	167	5	no	no	DT
cord-005603-kjcbbgse	167	6	major	major	JJ
cord-005603-kjcbbgse	167	7	difference	difference	NN
cord-005603-kjcbbgse	167	8	in	in	IN
cord-005603-kjcbbgse	167	9	the	the	DT
cord-005603-kjcbbgse	167	10	distribution	distribution	NN
cord-005603-kjcbbgse	167	11	of	of	IN
cord-005603-kjcbbgse	167	12	organisms	organism	NNS
cord-005603-kjcbbgse	167	13	when	when	WRB
cord-005603-kjcbbgse	167	14	comparing	compare	VBG
cord-005603-kjcbbgse	167	15	bacteraemic	bacteraemic	NNP
cord-005603-kjcbbgse	167	16	episodes	episode	NNS
cord-005603-kjcbbgse	167	17	associated	associate	VBN
cord-005603-kjcbbgse	167	18	with	with	IN
cord-005603-kjcbbgse	167	19	sepsis	sepsis	NN
cord-005603-kjcbbgse	167	20	only	only	RB
cord-005603-kjcbbgse	167	21	or	or	CC
cord-005603-kjcbbgse	167	22	with	with	IN
cord-005603-kjcbbgse	167	23	severe	severe	JJ
cord-005603-kjcbbgse	167	24	sepsis	sepsis	NN
cord-005603-kjcbbgse	167	25	,	,	,
cord-005603-kjcbbgse	167	26	except	except	IN
cord-005603-kjcbbgse	167	27	for	for	IN
cord-005603-kjcbbgse	167	28	a	a	DT
cord-005603-kjcbbgse	167	29	marginally	marginally	RB
cord-005603-kjcbbgse	167	30	higher	high	JJR
cord-005603-kjcbbgse	167	31	proportion	proportion	NN
cord-005603-kjcbbgse	167	32	of	of	IN
cord-005603-kjcbbgse	167	33	polymicrobial	polymicrobial	JJ
cord-005603-kjcbbgse	167	34	infection	infection	NN
cord-005603-kjcbbgse	167	35	(	(	-LRB-
cord-005603-kjcbbgse	167	36	Table	Table	NNP
cord-005603-kjcbbgse	167	37	4	4	CD
cord-005603-kjcbbgse	167	38	)	)	-RRB-
cord-005603-kjcbbgse	167	39	.	.	.
cord-005603-kjcbbgse	168	1	These	these	DT
cord-005603-kjcbbgse	168	2	data	datum	NNS
cord-005603-kjcbbgse	168	3	suggest	suggest	VBP
cord-005603-kjcbbgse	168	4	that	that	IN
cord-005603-kjcbbgse	168	5	the	the	DT
cord-005603-kjcbbgse	168	6	microbiologic	microbiologic	JJ
cord-005603-kjcbbgse	168	7	characteristics	characteristic	NNS
cord-005603-kjcbbgse	168	8	of	of	IN
cord-005603-kjcbbgse	168	9	infection	infection	NN
cord-005603-kjcbbgse	168	10	are	be	VBP
cord-005603-kjcbbgse	168	11	not	not	RB
cord-005603-kjcbbgse	168	12	a	a	DT
cord-005603-kjcbbgse	168	13	major	major	JJ
cord-005603-kjcbbgse	168	14	determinant	determinant	NN
cord-005603-kjcbbgse	168	15	of	of	IN
cord-005603-kjcbbgse	168	16	the	the	DT
cord-005603-kjcbbgse	168	17	clinical	clinical	JJ
cord-005603-kjcbbgse	168	18	presentation	presentation	NN
cord-005603-kjcbbgse	168	19	and	and	CC
cord-005603-kjcbbgse	168	20	intensity	intensity	NN
cord-005603-kjcbbgse	168	21	of	of	IN
cord-005603-kjcbbgse	168	22	the	the	DT
cord-005603-kjcbbgse	168	23	host	host	NN
cord-005603-kjcbbgse	168	24	response	response	NN
cord-005603-kjcbbgse	168	25	to	to	IN
cord-005603-kjcbbgse	168	26	infection	infection	NN
cord-005603-kjcbbgse	168	27	.	.	.
cord-005603-kjcbbgse	169	1	This	this	DT
cord-005603-kjcbbgse	169	2	notion	notion	NN
cord-005603-kjcbbgse	169	3	is	be	VBZ
cord-005603-kjcbbgse	169	4	also	also	RB
cord-005603-kjcbbgse	169	5	consistent	consistent	JJ
cord-005603-kjcbbgse	169	6	with	with	IN
cord-005603-kjcbbgse	169	7	the	the	DT
cord-005603-kjcbbgse	169	8	fact	fact	NN
cord-005603-kjcbbgse	169	9	that	that	IN
cord-005603-kjcbbgse	169	10	it	-PRON-	PRP
cord-005603-kjcbbgse	169	11	appears	appear	VBZ
cord-005603-kjcbbgse	169	12	quite	quite	RB
cord-005603-kjcbbgse	169	13	difficult	difficult	JJ
cord-005603-kjcbbgse	169	14	to	to	TO
cord-005603-kjcbbgse	169	15	predict	predict	VB
cord-005603-kjcbbgse	169	16	bacteraemia	bacteraemia	NN
cord-005603-kjcbbgse	169	17	in	in	IN
cord-005603-kjcbbgse	169	18	patients	patient	NNS
cord-005603-kjcbbgse	169	19	presenting	present	VBG
cord-005603-kjcbbgse	169	20	with	with	IN
cord-005603-kjcbbgse	169	21	clinical	clinical	JJ
cord-005603-kjcbbgse	169	22	sepsis	sepsis	NN
cord-005603-kjcbbgse	169	23	[	[	-LRB-
cord-005603-kjcbbgse	169	24	14	14	CD
cord-005603-kjcbbgse	169	25	]	]	-RRB-
cord-005603-kjcbbgse	169	26	.	.	.
cord-005603-kjcbbgse	170	1	It	-PRON-	PRP
cord-005603-kjcbbgse	170	2	is	be	VBZ
cord-005603-kjcbbgse	170	3	apparent	apparent	JJ
cord-005603-kjcbbgse	170	4	that	that	IN
cord-005603-kjcbbgse	170	5	the	the	DT
cord-005603-kjcbbgse	170	6	classification	classification	NN
cord-005603-kjcbbgse	170	7	into	into	IN
cord-005603-kjcbbgse	170	8	three	three	CD
cord-005603-kjcbbgse	170	9	major	major	JJ
cord-005603-kjcbbgse	170	10	syndromes	syndrome	NNS
cord-005603-kjcbbgse	170	11	(	(	-LRB-
cord-005603-kjcbbgse	170	12	sepsis	sepsis	NN
cord-005603-kjcbbgse	170	13	,	,	,
cord-005603-kjcbbgse	170	14	severe	severe	JJ
cord-005603-kjcbbgse	170	15	sepsis	sepsis	NN
cord-005603-kjcbbgse	170	16	,	,	,
cord-005603-kjcbbgse	170	17	and	and	CC
cord-005603-kjcbbgse	170	18	sepsis	sepsis	NN
cord-005603-kjcbbgse	170	19	shock	shock	NN
cord-005603-kjcbbgse	170	20	)	)	-RRB-
cord-005603-kjcbbgse	170	21	reflects	reflect	VBZ
cord-005603-kjcbbgse	170	22	a	a	DT
cord-005603-kjcbbgse	170	23	grading	grading	NN
cord-005603-kjcbbgse	170	24	in	in	IN
cord-005603-kjcbbgse	170	25	prognosis	prognosis	NN
cord-005603-kjcbbgse	170	26	of	of	IN
cord-005603-kjcbbgse	170	27	patients	patient	NNS
cord-005603-kjcbbgse	170	28	affected	affect	VBN
cord-005603-kjcbbgse	170	29	,	,	,
cord-005603-kjcbbgse	170	30	and	and	CC
cord-005603-kjcbbgse	170	31	this	this	DT
cord-005603-kjcbbgse	170	32	is	be	VBZ
cord-005603-kjcbbgse	170	33	clearly	clearly	RB
cord-005603-kjcbbgse	170	34	an	an	DT
cord-005603-kjcbbgse	170	35	important	important	JJ
cord-005603-kjcbbgse	170	36	outcome	outcome	NN
cord-005603-kjcbbgse	170	37	of	of	IN
cord-005603-kjcbbgse	170	38	the	the	DT
cord-005603-kjcbbgse	170	39	current	current	JJ
cord-005603-kjcbbgse	170	40	classification	classification	NN
cord-005603-kjcbbgse	170	41	.	.	.
cord-005603-kjcbbgse	171	1	There	there	EX
cord-005603-kjcbbgse	171	2	are	be	VBP
cord-005603-kjcbbgse	171	3	,	,	,
cord-005603-kjcbbgse	171	4	however	however	RB
cord-005603-kjcbbgse	171	5	,	,	,
cord-005603-kjcbbgse	171	6	wide	wide	JJ
cord-005603-kjcbbgse	171	7	variations	variation	NNS
cord-005603-kjcbbgse	171	8	in	in	IN
cord-005603-kjcbbgse	171	9	mortality	mortality	NN
cord-005603-kjcbbgse	171	10	rates	rate	NNS
cord-005603-kjcbbgse	171	11	reported	report	VBN
cord-005603-kjcbbgse	171	12	in	in	IN
cord-005603-kjcbbgse	171	13	cohorts	cohort	NNS
cord-005603-kjcbbgse	171	14	of	of	IN
cord-005603-kjcbbgse	171	15	patients	patient	NNS
cord-005603-kjcbbgse	171	16	with	with	IN
cord-005603-kjcbbgse	171	17	septic	septic	JJ
cord-005603-kjcbbgse	171	18	S	S	NNP
cord-005603-kjcbbgse	171	19	70	70	CD
cord-005603-kjcbbgse	172	1	*	*	NFP
cord-005603-kjcbbgse	172	2	P	p	NN
cord-005603-kjcbbgse	172	3	<	<	XX
cord-005603-kjcbbgse	172	4	0.001	0.001	CD
cord-005603-kjcbbgse	172	5	for	for	IN
cord-005603-kjcbbgse	172	6	comparison	comparison	NN
cord-005603-kjcbbgse	172	7	of	of	IN
cord-005603-kjcbbgse	172	8	sources	source	NNS
cord-005603-kjcbbgse	172	9	between	between	IN
cord-005603-kjcbbgse	172	10	episodes	episode	NNS
cord-005603-kjcbbgse	172	11	of	of	IN
cord-005603-kjcbbgse	172	12	bacteremic	bacteremic	JJ
cord-005603-kjcbbgse	172	13	sepsis	sepsis	NN
cord-005603-kjcbbgse	172	14	and	and	CC
cord-005603-kjcbbgse	172	15	bacteremic	bacteremic	JJ
cord-005603-kjcbbgse	172	16	severe	severe	JJ
cord-005603-kjcbbgse	172	17	sepsis	sepsis	NN
cord-005603-kjcbbgse	172	18	.	.	.
cord-005603-kjcbbgse	173	1	Data	datum	NNS
cord-005603-kjcbbgse	173	2	from	from	IN
cord-005603-kjcbbgse	173	3	[	[	-LRB-
cord-005603-kjcbbgse	173	4	5	5	CD
cord-005603-kjcbbgse	173	5	]	]	-RRB-
cord-005603-kjcbbgse	173	6	;	;	:
cord-005603-kjcbbgse	173	7	reproduced	reproduce	VBN
cord-005603-kjcbbgse	173	8	with	with	IN
cord-005603-kjcbbgse	173	9	permission	permission	NN
cord-005603-kjcbbgse	173	10	syndromes	syndrome	NNS
cord-005603-kjcbbgse	173	11	,	,	,
cord-005603-kjcbbgse	173	12	especially	especially	RB
cord-005603-kjcbbgse	173	13	for	for	IN
cord-005603-kjcbbgse	173	14	hospital	hospital	NN
cord-005603-kjcbbgse	173	15	-	-	HYPH
cord-005603-kjcbbgse	173	16	wide	wide	JJ
cord-005603-kjcbbgse	173	17	data	datum	NNS
cord-005603-kjcbbgse	173	18	.	.	.
cord-005603-kjcbbgse	174	1	In	in	IN
cord-005603-kjcbbgse	174	2	the	the	DT
cord-005603-kjcbbgse	174	3	study	study	NN
cord-005603-kjcbbgse	174	4	by	by	IN
cord-005603-kjcbbgse	174	5	Rangel	Rangel	NNP
cord-005603-kjcbbgse	174	6	-	-	HYPH
cord-005603-kjcbbgse	174	7	Fausto	Fausto	NNP
cord-005603-kjcbbgse	174	8	et	et	NNP
cord-005603-kjcbbgse	174	9	al	al	NNP
cord-005603-kjcbbgse	174	10	.	.	.
cord-005603-kjcbbgse	175	1	[	[	-LRB-
cord-005603-kjcbbgse	175	2	6	6	CD
cord-005603-kjcbbgse	175	3	,	,	,
cord-005603-kjcbbgse	175	4	7	7	CD
cord-005603-kjcbbgse	175	5	]	]	-RRB-
cord-005603-kjcbbgse	175	6	the	the	DT
cord-005603-kjcbbgse	175	7	28-day	28-day	CD
cord-005603-kjcbbgse	175	8	mortality	mortality	NN
cord-005603-kjcbbgse	175	9	of	of	IN
cord-005603-kjcbbgse	175	10	the	the	DT
cord-005603-kjcbbgse	175	11	different	different	JJ
cord-005603-kjcbbgse	175	12	stages	stage	NNS
cord-005603-kjcbbgse	175	13	from	from	IN
cord-005603-kjcbbgse	175	14	SIRS	SIRS	NNP
cord-005603-kjcbbgse	175	15	to	to	IN
cord-005603-kjcbbgse	175	16	septic	septic	JJ
cord-005603-kjcbbgse	175	17	shock	shock	NN
cord-005603-kjcbbgse	175	18	was	be	VBD
cord-005603-kjcbbgse	175	19	7	7	CD
cord-005603-kjcbbgse	175	20	%	%	NN
cord-005603-kjcbbgse	175	21	,	,	,
cord-005603-kjcbbgse	175	22	16	16	CD
cord-005603-kjcbbgse	175	23	%	%	NN
cord-005603-kjcbbgse	175	24	,	,	,
cord-005603-kjcbbgse	175	25	20	20	CD
cord-005603-kjcbbgse	175	26	%	%	NN
cord-005603-kjcbbgse	175	27	,	,	,
cord-005603-kjcbbgse	175	28	and	and	CC
cord-005603-kjcbbgse	175	29	46	46	CD
cord-005603-kjcbbgse	175	30	%	%	NN
cord-005603-kjcbbgse	175	31	for	for	IN
cord-005603-kjcbbgse	175	32	SIRS	SIRS	NNP
cord-005603-kjcbbgse	175	33	,	,	,
cord-005603-kjcbbgse	175	34	sepsis	sepsis	NN
cord-005603-kjcbbgse	175	35	,	,	,
cord-005603-kjcbbgse	175	36	severe	severe	JJ
cord-005603-kjcbbgse	175	37	sepsis	sepsis	NN
cord-005603-kjcbbgse	175	38	and	and	CC
cord-005603-kjcbbgse	175	39	septic	septic	JJ
cord-005603-kjcbbgse	175	40	shock	shock	NN
cord-005603-kjcbbgse	175	41	,	,	,
cord-005603-kjcbbgse	175	42	respectively	respectively	RB
cord-005603-kjcbbgse	175	43	.	.	.
cord-005603-kjcbbgse	176	1	In	in	IN
cord-005603-kjcbbgse	176	2	the	the	DT
cord-005603-kjcbbgse	176	3	study	study	NN
cord-005603-kjcbbgse	176	4	conducted	conduct	VBN
cord-005603-kjcbbgse	176	5	by	by	IN
cord-005603-kjcbbgse	176	6	Sands	Sands	NNPS
cord-005603-kjcbbgse	176	7	et	et	NNP
cord-005603-kjcbbgse	176	8	al	al	NNP
cord-005603-kjcbbgse	176	9	.	.	.
cord-005603-kjcbbgse	177	1	[	[	-LRB-
cord-005603-kjcbbgse	177	2	8	8	CD
cord-005603-kjcbbgse	177	3	,	,	,
cord-005603-kjcbbgse	177	4	14	14	CD
cord-005603-kjcbbgse	177	5	]	]	-RRB-
cord-005603-kjcbbgse	177	6	the	the	DT
cord-005603-kjcbbgse	177	7	28-day	28-day	CD
cord-005603-kjcbbgse	177	8	mortality	mortality	NN
cord-005603-kjcbbgse	177	9	of	of	IN
cord-005603-kjcbbgse	177	10	patients	patient	NNS
cord-005603-kjcbbgse	177	11	with	with	IN
cord-005603-kjcbbgse	177	12	severe	severe	JJ
cord-005603-kjcbbgse	177	13	sepsis	sepsis	NN
cord-005603-kjcbbgse	177	14	and	and	CC
cord-005603-kjcbbgse	177	15	septic	septic	JJ
cord-005603-kjcbbgse	177	16	shock	shock	NN
cord-005603-kjcbbgse	177	17	was	be	VBD
cord-005603-kjcbbgse	177	18	34	34	CD
cord-005603-kjcbbgse	177	19	%	%	NN
cord-005603-kjcbbgse	177	20	.	.	.
cord-005603-kjcbbgse	178	1	In	in	IN
cord-005603-kjcbbgse	178	2	the	the	DT
cord-005603-kjcbbgse	178	3	French	french	JJ
cord-005603-kjcbbgse	178	4	multicenter	multicenter	JJ
cord-005603-kjcbbgse	178	5	study	study	NN
cord-005603-kjcbbgse	178	6	,	,	,
cord-005603-kjcbbgse	178	7	the	the	DT
cord-005603-kjcbbgse	178	8	28-day	28-day	CD
cord-005603-kjcbbgse	178	9	mortality	mortality	NN
cord-005603-kjcbbgse	178	10	was	be	VBD
cord-005603-kjcbbgse	178	11	25	25	CD
cord-005603-kjcbbgse	178	12	%	%	NN
cord-005603-kjcbbgse	178	13	in	in	IN
cord-005603-kjcbbgse	178	14	patients	patient	NNS
cord-005603-kjcbbgse	178	15	with	with	IN
cord-005603-kjcbbgse	178	16	bacteraemic	bacteraemic	NNP
cord-005603-kjcbbgse	178	17	sepsis	sepsis	NN
cord-005603-kjcbbgse	178	18	(	(	-LRB-
cord-005603-kjcbbgse	178	19	19	19	CD
cord-005603-kjcbbgse	178	20	%	%	NN
cord-005603-kjcbbgse	178	21	in	in	IN
cord-005603-kjcbbgse	178	22	ward	ward	NN
cord-005603-kjcbbgse	178	23	patients	patient	NNS
cord-005603-kjcbbgse	178	24	)	)	-RRB-
cord-005603-kjcbbgse	178	25	,	,	,
cord-005603-kjcbbgse	178	26	and	and	CC
cord-005603-kjcbbgse	178	27	of	of	IN
cord-005603-kjcbbgse	178	28	54	54	CD
cord-005603-kjcbbgse	178	29	%	%	NN
cord-005603-kjcbbgse	178	30	in	in	IN
cord-005603-kjcbbgse	178	31	patients	patient	NNS
cord-005603-kjcbbgse	178	32	with	with	IN
cord-005603-kjcbbgse	178	33	bacteraemic	bacteraemic	NNP
cord-005603-kjcbbgse	178	34	severe	severe	JJ
cord-005603-kjcbbgse	178	35	sepsis	sepsis	NN
cord-005603-kjcbbgse	178	36	or	or	CC
cord-005603-kjcbbgse	178	37	shock	shock	NN
cord-005603-kjcbbgse	178	38	[	[	-LRB-
cord-005603-kjcbbgse	178	39	5	5	CD
cord-005603-kjcbbgse	178	40	]	]	-RRB-
cord-005603-kjcbbgse	178	41	.	.	.
cord-005603-kjcbbgse	179	1	In	in	IN
cord-005603-kjcbbgse	179	2	studies	study	NNS
cord-005603-kjcbbgse	179	3	restricted	restrict	VBN
cord-005603-kjcbbgse	179	4	to	to	IN
cord-005603-kjcbbgse	179	5	ICU	ICU	NNP
cord-005603-kjcbbgse	179	6	patients	patient	NNS
cord-005603-kjcbbgse	179	7	,	,	,
cord-005603-kjcbbgse	179	8	mortality	mortality	NN
cord-005603-kjcbbgse	179	9	rates	rate	NNS
cord-005603-kjcbbgse	179	10	were	be	VBD
cord-005603-kjcbbgse	179	11	slightly	slightly	RB
cord-005603-kjcbbgse	179	12	more	more	RBR
cord-005603-kjcbbgse	179	13	consistent	consistent	JJ
cord-005603-kjcbbgse	179	14	across	across	IN
cord-005603-kjcbbgse	179	15	studies	study	NNS
cord-005603-kjcbbgse	179	16	.	.	.
cord-005603-kjcbbgse	180	1	Pittet	Pittet	NNP
cord-005603-kjcbbgse	180	2	et	et	FW
cord-005603-kjcbbgse	180	3	al	al	NNP
cord-005603-kjcbbgse	180	4	.	.	NNP
cord-005603-kjcbbgse	180	5	,	,	,
cord-005603-kjcbbgse	180	6	reported	report	VBD
cord-005603-kjcbbgse	180	7	a	a	DT
cord-005603-kjcbbgse	180	8	28-day	28-day	CD
cord-005603-kjcbbgse	180	9	and	and	CC
cord-005603-kjcbbgse	180	10	hospital	hospital	NN
cord-005603-kjcbbgse	180	11	mortality	mortality	NN
cord-005603-kjcbbgse	180	12	rate	rate	NN
cord-005603-kjcbbgse	180	13	of	of	IN
cord-005603-kjcbbgse	180	14	bacteraemic	bacteraemic	NNP
cord-005603-kjcbbgse	180	15	sepsis	sepsis	NN
cord-005603-kjcbbgse	180	16	of	of	IN
cord-005603-kjcbbgse	180	17	35	35	CD
cord-005603-kjcbbgse	180	18	%	%	NN
cord-005603-kjcbbgse	180	19	and	and	CC
cord-005603-kjcbbgse	180	20	43	43	CD
cord-005603-kjcbbgse	180	21	%	%	NN
cord-005603-kjcbbgse	180	22	,	,	,
cord-005603-kjcbbgse	180	23	respectively	respectively	RB
cord-005603-kjcbbgse	180	24	[	[	-LRB-
cord-005603-kjcbbgse	180	25	17	17	CD
cord-005603-kjcbbgse	180	26	]	]	-RRB-
cord-005603-kjcbbgse	180	27	;	;	:
cord-005603-kjcbbgse	180	28	77	77	CD
cord-005603-kjcbbgse	180	29	%	%	NN
cord-005603-kjcbbgse	180	30	of	of	IN
cord-005603-kjcbbgse	180	31	these	these	DT
cord-005603-kjcbbgse	180	32	patients	patient	NNS
cord-005603-kjcbbgse	180	33	had	have	VBD
cord-005603-kjcbbgse	180	34	severe	severe	JJ
cord-005603-kjcbbgse	180	35	sepsis	sepsis	NN
cord-005603-kjcbbgse	180	36	,	,	,
cord-005603-kjcbbgse	180	37	as	as	IN
cord-005603-kjcbbgse	180	38	assessed	assess	VBN
cord-005603-kjcbbgse	180	39	by	by	IN
cord-005603-kjcbbgse	180	40	the	the	DT
cord-005603-kjcbbgse	180	41	presence	presence	NN
cord-005603-kjcbbgse	180	42	of	of	IN
cord-005603-kjcbbgse	180	43	organ	organ	NN
cord-005603-kjcbbgse	180	44	dysfunction	dysfunction	NN
cord-005603-kjcbbgse	180	45	at	at	IN
cord-005603-kjcbbgse	180	46	onset	onset	NN
cord-005603-kjcbbgse	180	47	or	or	CC
cord-005603-kjcbbgse	180	48	secondarily	secondarily	RB
cord-005603-kjcbbgse	180	49	.	.	.
cord-005603-kjcbbgse	181	1	Brun	Brun	NNP
cord-005603-kjcbbgse	181	2	-	-	HYPH
cord-005603-kjcbbgse	181	3	Buisson	Buisson	NNP
cord-005603-kjcbbgse	181	4	et	et	FW
cord-005603-kjcbbgse	181	5	al	al	NNP
cord-005603-kjcbbgse	181	6	.	.	.
cord-005603-kjcbbgse	182	1	,	,	,
cord-005603-kjcbbgse	182	2	reported	report	VBD
cord-005603-kjcbbgse	182	3	a	a	DT
cord-005603-kjcbbgse	182	4	28-day	28-day	CD
cord-005603-kjcbbgse	182	5	mortality	mortality	NN
cord-005603-kjcbbgse	182	6	of	of	IN
cord-005603-kjcbbgse	182	7	55	55	CD
cord-005603-kjcbbgse	182	8	%	%	NN
cord-005603-kjcbbgse	182	9	in	in	IN
cord-005603-kjcbbgse	182	10	ICU	ICU	NNP
cord-005603-kjcbbgse	182	11	patients	patient	NNS
cord-005603-kjcbbgse	182	12	with	with	IN
cord-005603-kjcbbgse	182	13	bacteraemic	bacteraemic	NNP
cord-005603-kjcbbgse	182	14	sepsis	sepsis	NN
cord-005603-kjcbbgse	182	15	,	,	,
cord-005603-kjcbbgse	182	16	65	65	CD
cord-005603-kjcbbgse	182	17	%	%	NN
cord-005603-kjcbbgse	182	18	of	of	IN
cord-005603-kjcbbgse	182	19	whom	whom	WP
cord-005603-kjcbbgse	182	20	had	have	VBD
cord-005603-kjcbbgse	182	21	severe	severe	JJ
cord-005603-kjcbbgse	182	22	sepsis	sepsis	NN
cord-005603-kjcbbgse	182	23	or	or	CC
cord-005603-kjcbbgse	182	24	shock	shock	NN
cord-005603-kjcbbgse	182	25	[	[	-LRB-
cord-005603-kjcbbgse	182	26	5	5	CD
cord-005603-kjcbbgse	182	27	]	]	-RRB-
cord-005603-kjcbbgse	182	28	;	;	:
cord-005603-kjcbbgse	182	29	overall	overall	RB
cord-005603-kjcbbgse	182	30	,	,	,
cord-005603-kjcbbgse	182	31	mortality	mortality	NN
cord-005603-kjcbbgse	182	32	was	be	VBD
cord-005603-kjcbbgse	182	33	56	56	CD
cord-005603-kjcbbgse	182	34	%	%	NN
cord-005603-kjcbbgse	182	35	at	at	IN
cord-005603-kjcbbgse	182	36	28	28	CD
cord-005603-kjcbbgse	182	37	days	day	NNS
cord-005603-kjcbbgse	182	38	after	after	IN
cord-005603-kjcbbgse	182	39	severe	severe	JJ
cord-005603-kjcbbgse	182	40	sepsis	sepsis	NN
cord-005603-kjcbbgse	182	41	among	among	IN
cord-005603-kjcbbgse	182	42	1052	1052	CD
cord-005603-kjcbbgse	182	43	ICU	ICU	NNP
cord-005603-kjcbbgse	182	44	patients	patient	NNS
cord-005603-kjcbbgse	182	45	,	,	,
cord-005603-kjcbbgse	182	46	of	of	IN
cord-005603-kjcbbgse	182	47	whom	whom	WP
cord-005603-kjcbbgse	182	48	71	71	CD
cord-005603-kjcbbgse	182	49	%	%	NN
cord-005603-kjcbbgse	182	50	had	have	VBD
cord-005603-kjcbbgse	182	51	septic	septic	JJ
cord-005603-kjcbbgse	182	52	shock	shock	NN
cord-005603-kjcbbgse	182	53	[	[	-LRB-
cord-005603-kjcbbgse	182	54	13	13	CD
cord-005603-kjcbbgse	182	55	]	]	-RRB-
cord-005603-kjcbbgse	182	56	.	.	.
cord-005603-kjcbbgse	183	1	It	-PRON-	PRP
cord-005603-kjcbbgse	183	2	is	be	VBZ
cord-005603-kjcbbgse	183	3	apparent	apparent	JJ
cord-005603-kjcbbgse	183	4	that	that	IN
cord-005603-kjcbbgse	183	5	the	the	DT
cord-005603-kjcbbgse	183	6	mortality	mortality	NN
cord-005603-kjcbbgse	183	7	rate	rate	NN
cord-005603-kjcbbgse	183	8	for	for	IN
cord-005603-kjcbbgse	183	9	a	a	DT
cord-005603-kjcbbgse	183	10	given	give	VBN
cord-005603-kjcbbgse	183	11	stage	stage	NN
cord-005603-kjcbbgse	183	12	upon	upon	IN
cord-005603-kjcbbgse	183	13	inclusion	inclusion	NN
cord-005603-kjcbbgse	183	14	is	be	VBZ
cord-005603-kjcbbgse	183	15	dependent	dependent	JJ
cord-005603-kjcbbgse	183	16	in	in	IN
cord-005603-kjcbbgse	183	17	large	large	JJ
cord-005603-kjcbbgse	183	18	part	part	NN
cord-005603-kjcbbgse	183	19	on	on	IN
cord-005603-kjcbbgse	183	20	the	the	DT
cord-005603-kjcbbgse	183	21	proportion	proportion	NN
cord-005603-kjcbbgse	183	22	of	of	IN
cord-005603-kjcbbgse	183	23	patients	patient	NNS
cord-005603-kjcbbgse	183	24	rapidly	rapidly	RB
cord-005603-kjcbbgse	183	25	evolving	evolve	VBG
cord-005603-kjcbbgse	183	26	to	to	IN
cord-005603-kjcbbgse	183	27	a	a	DT
cord-005603-kjcbbgse	183	28	more	more	RBR
cord-005603-kjcbbgse	183	29	severe	severe	JJ
cord-005603-kjcbbgse	183	30	stage	stage	NN
cord-005603-kjcbbgse	183	31	.	.	.
cord-005603-kjcbbgse	184	1	Knaus	Knaus	NNP
cord-005603-kjcbbgse	184	2	et	et	NNP
cord-005603-kjcbbgse	184	3	al	al	NNP
cord-005603-kjcbbgse	184	4	.	.	NNP
cord-005603-kjcbbgse	184	5	,	,	,
cord-005603-kjcbbgse	184	6	have	have	VBP
cord-005603-kjcbbgse	184	7	shown	show	VBN
cord-005603-kjcbbgse	184	8	that	that	IN
cord-005603-kjcbbgse	184	9	a	a	DT
cord-005603-kjcbbgse	184	10	wide	wide	JJ
cord-005603-kjcbbgse	184	11	range	range	NN
cord-005603-kjcbbgse	184	12	of	of	IN
cord-005603-kjcbbgse	184	13	mortality	mortality	NN
cord-005603-kjcbbgse	184	14	risk	risk	NN
cord-005603-kjcbbgse	184	15	could	could	MD
cord-005603-kjcbbgse	184	16	be	be	VB
cord-005603-kjcbbgse	184	17	observed	observe	VBN
cord-005603-kjcbbgse	184	18	in	in	IN
cord-005603-kjcbbgse	184	19	patients	patient	NNS
cord-005603-kjcbbgse	184	20	classified	classify	VBN
cord-005603-kjcbbgse	184	21	as	as	IN
cord-005603-kjcbbgse	184	22	having	have	VBG
cord-005603-kjcbbgse	184	23	sepsis	sepsis	NN
cord-005603-kjcbbgse	184	24	or	or	CC
cord-005603-kjcbbgse	184	25	even	even	RB
cord-005603-kjcbbgse	184	26	shock	shock	VB
cord-005603-kjcbbgse	184	27	[	[	-LRB-
cord-005603-kjcbbgse	184	28	18	18	CD
cord-005603-kjcbbgse	184	29	]	]	-RRB-
cord-005603-kjcbbgse	184	30	.	.	.
cord-005603-kjcbbgse	185	1	Further	further	JJ
cord-005603-kjcbbgse	185	2	insight	insight	NN
cord-005603-kjcbbgse	185	3	into	into	IN
cord-005603-kjcbbgse	185	4	a	a	DT
cord-005603-kjcbbgse	185	5	better	well	JJR
cord-005603-kjcbbgse	185	6	characterisation	characterisation	NN
cord-005603-kjcbbgse	185	7	of	of	IN
cord-005603-kjcbbgse	185	8	outcome	outcome	NN
cord-005603-kjcbbgse	185	9	for	for	IN
cord-005603-kjcbbgse	185	10	septic	septic	JJ
cord-005603-kjcbbgse	185	11	patients	patient	NNS
cord-005603-kjcbbgse	185	12	has	have	VBZ
cord-005603-kjcbbgse	185	13	been	be	VBN
cord-005603-kjcbbgse	185	14	provided	provide	VBN
cord-005603-kjcbbgse	185	15	by	by	IN
cord-005603-kjcbbgse	185	16	studies	study	NNS
cord-005603-kjcbbgse	185	17	looking	look	VBG
cord-005603-kjcbbgse	185	18	at	at	IN
cord-005603-kjcbbgse	185	19	mortality	mortality	NN
cord-005603-kjcbbgse	185	20	risk	risk	NN
cord-005603-kjcbbgse	185	21	adjustment	adjustment	NN
cord-005603-kjcbbgse	185	22	through	through	IN
cord-005603-kjcbbgse	185	23	risk	risk	NN
cord-005603-kjcbbgse	185	24	factors	factor	NNS
cord-005603-kjcbbgse	185	25	analyses	analysis	NNS
cord-005603-kjcbbgse	185	26	and	and	CC
cord-005603-kjcbbgse	185	27	models	model	NNS
cord-005603-kjcbbgse	185	28	specific	specific	JJ
cord-005603-kjcbbgse	185	29	to	to	IN
cord-005603-kjcbbgse	185	30	septic	septic	JJ
cord-005603-kjcbbgse	185	31	patients	patient	NNS
cord-005603-kjcbbgse	185	32	.	.	.
cord-005603-kjcbbgse	186	1	As	as	IN
cord-005603-kjcbbgse	186	2	for	for	IN
cord-005603-kjcbbgse	186	3	all	all	DT
cord-005603-kjcbbgse	186	4	ICU	ICU	NNP
cord-005603-kjcbbgse	186	5	patients	patient	NNS
cord-005603-kjcbbgse	186	6	,	,	,
cord-005603-kjcbbgse	186	7	there	there	EX
cord-005603-kjcbbgse	186	8	are	be	VBP
cord-005603-kjcbbgse	186	9	two	two	CD
cord-005603-kjcbbgse	186	10	major	major	JJ
cord-005603-kjcbbgse	186	11	determinants	determinant	NNS
cord-005603-kjcbbgse	186	12	of	of	IN
cord-005603-kjcbbgse	186	13	outcome	outcome	NN
cord-005603-kjcbbgse	186	14	for	for	IN
cord-005603-kjcbbgse	186	15	septic	septic	JJ
cord-005603-kjcbbgse	186	16	patients	patient	NNS
cord-005603-kjcbbgse	186	17	:	:	:
cord-005603-kjcbbgse	186	18	the	the	DT
cord-005603-kjcbbgse	186	19	severity	severity	NN
cord-005603-kjcbbgse	186	20	of	of	IN
cord-005603-kjcbbgse	186	21	underlying	underlie	VBG
cord-005603-kjcbbgse	186	22	disease	disease	NN
cord-005603-kjcbbgse	186	23	,	,	,
cord-005603-kjcbbgse	186	24	and	and	CC
cord-005603-kjcbbgse	186	25	the	the	DT
cord-005603-kjcbbgse	186	26	severity	severity	NN
cord-005603-kjcbbgse	186	27	of	of	IN
cord-005603-kjcbbgse	186	28	acute	acute	JJ
cord-005603-kjcbbgse	186	29	illness	illness	NN
cord-005603-kjcbbgse	186	30	.	.	.
cord-005603-kjcbbgse	187	1	Severity	severity	NN
cord-005603-kjcbbgse	187	2	of	of	IN
cord-005603-kjcbbgse	187	3	underlying	underlie	VBG
cord-005603-kjcbbgse	187	4	disease	disease	NN
cord-005603-kjcbbgse	187	5	has	have	VBZ
cord-005603-kjcbbgse	187	6	been	be	VBN
cord-005603-kjcbbgse	187	7	assessed	assess	VBN
cord-005603-kjcbbgse	187	8	via	via	IN
cord-005603-kjcbbgse	187	9	several	several	JJ
cord-005603-kjcbbgse	187	10	indexes	index	NNS
cord-005603-kjcbbgse	187	11	or	or	CC
cord-005603-kjcbbgse	187	12	systems	system	NNS
cord-005603-kjcbbgse	187	13	,	,	,
cord-005603-kjcbbgse	187	14	such	such	JJ
cord-005603-kjcbbgse	187	15	as	as	IN
cord-005603-kjcbbgse	187	16	the	the	DT
cord-005603-kjcbbgse	187	17	simple	simple	NN
cord-005603-kjcbbgse	187	18	(	(	-LRB-
cord-005603-kjcbbgse	187	19	and	and	CC
cord-005603-kjcbbgse	187	20	robust	robust	JJ
cord-005603-kjcbbgse	187	21	,	,	,
cord-005603-kjcbbgse	187	22	but	but	CC
cord-005603-kjcbbgse	187	23	somewhat	somewhat	RB
cord-005603-kjcbbgse	187	24	subjective	subjective	JJ
cord-005603-kjcbbgse	187	25	)	)	-RRB-
cord-005603-kjcbbgse	187	26	three	three	CD
cord-005603-kjcbbgse	187	27	-	-	HYPH
cord-005603-kjcbbgse	187	28	classes	class	NNS
cord-005603-kjcbbgse	187	29	index	index	NN
cord-005603-kjcbbgse	187	30	developed	develop	VBN
cord-005603-kjcbbgse	187	31	by	by	IN
cord-005603-kjcbbgse	187	32	MacCabe	MacCabe	NNP
cord-005603-kjcbbgse	187	33	et	et	NNP
cord-005603-kjcbbgse	187	34	al	al	NNP
cord-005603-kjcbbgse	187	35	.	.	NNP
cord-005603-kjcbbgse	187	36	,	,	,
cord-005603-kjcbbgse	187	37	for	for	IN
cord-005603-kjcbbgse	187	38	bacteraemic	bacteraemic	NNP
cord-005603-kjcbbgse	187	39	patients	patient	NNS
cord-005603-kjcbbgse	187	40	[	[	-LRB-
cord-005603-kjcbbgse	187	41	19	19	CD
cord-005603-kjcbbgse	187	42	,	,	,
cord-005603-kjcbbgse	187	43	20	20	CD
cord-005603-kjcbbgse	187	44	]	]	-RRB-
cord-005603-kjcbbgse	187	45	or	or	CC
cord-005603-kjcbbgse	187	46	a	a	DT
cord-005603-kjcbbgse	187	47	comorbidity	comorbidity	NN
cord-005603-kjcbbgse	187	48	scoring	scoring	NN
cord-005603-kjcbbgse	187	49	index	index	NN
cord-005603-kjcbbgse	187	50	,	,	,
cord-005603-kjcbbgse	187	51	a	a	DT
cord-005603-kjcbbgse	187	52	system	system	NN
cord-005603-kjcbbgse	187	53	primarily	primarily	RB
cord-005603-kjcbbgse	187	54	developed	develop	VBD
cord-005603-kjcbbgse	187	55	for	for	IN
cord-005603-kjcbbgse	187	56	adjusting	adjust	VBG
cord-005603-kjcbbgse	187	57	the	the	DT
cord-005603-kjcbbgse	187	58	risk	risk	NN
cord-005603-kjcbbgse	187	59	of	of	IN
cord-005603-kjcbbgse	187	60	nosocomial	nosocomial	JJ
cord-005603-kjcbbgse	187	61	infection	infection	NN
cord-005603-kjcbbgse	187	62	[	[	-LRB-
cord-005603-kjcbbgse	187	63	21	21	CD
cord-005603-kjcbbgse	187	64	]	]	-RRB-
cord-005603-kjcbbgse	187	65	;	;	:
cord-005603-kjcbbgse	187	66	finally	finally	RB
cord-005603-kjcbbgse	187	67	,	,	,
cord-005603-kjcbbgse	187	68	general	general	JJ
cord-005603-kjcbbgse	187	69	scoring	scoring	NN
cord-005603-kjcbbgse	187	70	systems	system	NNS
cord-005603-kjcbbgse	187	71	such	such	JJ
cord-005603-kjcbbgse	187	72	as	as	IN
cord-005603-kjcbbgse	187	73	the	the	DT
cord-005603-kjcbbgse	187	74	APACHE	APACHE	NNP
cord-005603-kjcbbgse	187	75	II	II	NNP
cord-005603-kjcbbgse	187	76	include	include	VBP
cord-005603-kjcbbgse	187	77	comorbidities	comorbiditie	NNS
cord-005603-kjcbbgse	187	78	,	,	,
cord-005603-kjcbbgse	187	79	expressed	express	VBN
cord-005603-kjcbbgse	187	80	as	as	IN
cord-005603-kjcbbgse	187	81	pre	pre	JJ
cord-005603-kjcbbgse	187	82	-	-	JJ
cord-005603-kjcbbgse	187	83	existing	existing	JJ
cord-005603-kjcbbgse	187	84	organ	organ	NN
cord-005603-kjcbbgse	187	85	dysfunction	dysfunction	NN
cord-005603-kjcbbgse	187	86	for	for	IN
cord-005603-kjcbbgse	187	87	the	the	DT
cord-005603-kjcbbgse	187	88	four	four	CD
cord-005603-kjcbbgse	187	89	major	major	JJ
cord-005603-kjcbbgse	187	90	organ	organ	NN
cord-005603-kjcbbgse	187	91	systems	system	NNS
cord-005603-kjcbbgse	187	92	(	(	-LRB-
cord-005603-kjcbbgse	187	93	respiratory	respiratory	JJ
cord-005603-kjcbbgse	187	94	,	,	,
cord-005603-kjcbbgse	187	95	cardiovascular	cardiovascular	JJ
cord-005603-kjcbbgse	187	96	,	,	,
cord-005603-kjcbbgse	187	97	renal	renal	JJ
cord-005603-kjcbbgse	187	98	,	,	,
cord-005603-kjcbbgse	187	99	and	and	CC
cord-005603-kjcbbgse	187	100	liver	liver	NN
cord-005603-kjcbbgse	187	101	)	)	-RRB-
cord-005603-kjcbbgse	187	102	,	,	,
cord-005603-kjcbbgse	187	103	or	or	CC
cord-005603-kjcbbgse	187	104	include	include	VBP
cord-005603-kjcbbgse	187	105	a	a	DT
cord-005603-kjcbbgse	187	106	few	few	JJ
cord-005603-kjcbbgse	187	107	major	major	JJ
cord-005603-kjcbbgse	187	108	comorbidities	comorbiditie	NNS
cord-005603-kjcbbgse	187	109	such	such	JJ
cord-005603-kjcbbgse	187	110	as	as	IN
cord-005603-kjcbbgse	187	111	in	in	IN
cord-005603-kjcbbgse	187	112	the	the	DT
cord-005603-kjcbbgse	187	113	SAPS	SAPS	NNP
cord-005603-kjcbbgse	187	114	II	II	NNP
cord-005603-kjcbbgse	187	115	(	(	-LRB-
cord-005603-kjcbbgse	187	116	AIDS	AIDS	NNP
cord-005603-kjcbbgse	187	117	,	,	,
cord-005603-kjcbbgse	187	118	metastatic	metastatic	JJ
cord-005603-kjcbbgse	187	119	cancer	cancer	NN
cord-005603-kjcbbgse	187	120	,	,	,
cord-005603-kjcbbgse	187	121	and	and	CC
cord-005603-kjcbbgse	187	122	haematological	haematological	JJ
cord-005603-kjcbbgse	187	123	malignancy	malignancy	NN
cord-005603-kjcbbgse	187	124	)	)	-RRB-
cord-005603-kjcbbgse	187	125	[	[	-LRB-
cord-005603-kjcbbgse	187	126	22	22	CD
cord-005603-kjcbbgse	187	127	]	]	-RRB-
cord-005603-kjcbbgse	187	128	.	.	.
cord-005603-kjcbbgse	188	1	A	a	DT
cord-005603-kjcbbgse	188	2	more	more	RBR
cord-005603-kjcbbgse	188	3	complete	complete	JJ
cord-005603-kjcbbgse	188	4	assessment	assessment	NN
cord-005603-kjcbbgse	188	5	of	of	IN
cord-005603-kjcbbgse	188	6	pre	pre	JJ
cord-005603-kjcbbgse	188	7	-	-	JJ
cord-005603-kjcbbgse	188	8	existing	existing	JJ
cord-005603-kjcbbgse	188	9	conditions	condition	NNS
cord-005603-kjcbbgse	188	10	can	can	MD
cord-005603-kjcbbgse	188	11	probably	probably	RB
cord-005603-kjcbbgse	188	12	be	be	VB
cord-005603-kjcbbgse	188	13	obtained	obtain	VBN
cord-005603-kjcbbgse	188	14	by	by	IN
cord-005603-kjcbbgse	188	15	ascribing	ascribe	VBG
cord-005603-kjcbbgse	188	16	a	a	DT
cord-005603-kjcbbgse	188	17	weighted	weighted	JJ
cord-005603-kjcbbgse	188	18	score	score	NN
cord-005603-kjcbbgse	188	19	to	to	IN
cord-005603-kjcbbgse	188	20	diagnosis	diagnosis	NN
cord-005603-kjcbbgse	188	21	and	and	CC
cord-005603-kjcbbgse	188	22	comorbidities	comorbiditie	NNS
cord-005603-kjcbbgse	188	23	,	,	,
cord-005603-kjcbbgse	188	24	as	as	IN
cord-005603-kjcbbgse	188	25	used	use	VBN
cord-005603-kjcbbgse	188	26	in	in	IN
cord-005603-kjcbbgse	188	27	the	the	DT
cord-005603-kjcbbgse	188	28	APACHE	APACHE	NNP
cord-005603-kjcbbgse	188	29	II	II	NNP
cord-005603-kjcbbgse	188	30	and	and	CC
cord-005603-kjcbbgse	188	31	III	III	NNP
cord-005603-kjcbbgse	188	32	scoring	scoring	NN
cord-005603-kjcbbgse	188	33	systems	system	NNS
cord-005603-kjcbbgse	188	34	[	[	-LRB-
cord-005603-kjcbbgse	188	35	18	18	CD
cord-005603-kjcbbgse	188	36	]	]	-RRB-
cord-005603-kjcbbgse	188	37	.	.	.
cord-005603-kjcbbgse	189	1	Stratifying	stratify	VBG
cord-005603-kjcbbgse	189	2	patients	patient	NNS
cord-005603-kjcbbgse	189	3	by	by	IN
cord-005603-kjcbbgse	189	4	risk	risk	NN
cord-005603-kjcbbgse	189	5	class	class	NN
cord-005603-kjcbbgse	189	6	according	accord	VBG
cord-005603-kjcbbgse	189	7	to	to	IN
cord-005603-kjcbbgse	189	8	one	one	CD
cord-005603-kjcbbgse	189	9	of	of	IN
cord-005603-kjcbbgse	189	10	the	the	DT
cord-005603-kjcbbgse	189	11	general	general	JJ
cord-005603-kjcbbgse	189	12	scores	score	NNS
cord-005603-kjcbbgse	189	13	provides	provide	VBZ
cord-005603-kjcbbgse	189	14	a	a	DT
cord-005603-kjcbbgse	189	15	more	more	RBR
cord-005603-kjcbbgse	189	16	accurate	accurate	JJ
cord-005603-kjcbbgse	189	17	risk	risk	NN
cord-005603-kjcbbgse	189	18	prediction	prediction	NN
cord-005603-kjcbbgse	189	19	of	of	IN
cord-005603-kjcbbgse	189	20	outcome	outcome	NN
cord-005603-kjcbbgse	189	21	for	for	IN
cord-005603-kjcbbgse	189	22	septic	septic	JJ
cord-005603-kjcbbgse	189	23	patients	patient	NNS
cord-005603-kjcbbgse	189	24	than	than	IN
cord-005603-kjcbbgse	189	25	a	a	DT
cord-005603-kjcbbgse	189	26	simple	simple	JJ
cord-005603-kjcbbgse	189	27	stratification	stratification	NN
cord-005603-kjcbbgse	189	28	in	in	IN
cord-005603-kjcbbgse	189	29	one	one	CD
cord-005603-kjcbbgse	189	30	of	of	IN
cord-005603-kjcbbgse	189	31	the	the	DT
cord-005603-kjcbbgse	189	32	stages	stage	NNS
cord-005603-kjcbbgse	189	33	of	of	IN
cord-005603-kjcbbgse	189	34	sepsis	sepsis	NN
cord-005603-kjcbbgse	189	35	[	[	-LRB-
cord-005603-kjcbbgse	189	36	18	18	CD
cord-005603-kjcbbgse	189	37	]	]	-RRB-
cord-005603-kjcbbgse	189	38	.	.	.
cord-005603-kjcbbgse	190	1	Further	further	JJ
cord-005603-kjcbbgse	190	2	analysis	analysis	NN
cord-005603-kjcbbgse	190	3	of	of	IN
cord-005603-kjcbbgse	190	4	the	the	DT
cord-005603-kjcbbgse	190	5	performance	performance	NN
cord-005603-kjcbbgse	190	6	of	of	IN
cord-005603-kjcbbgse	190	7	these	these	DT
cord-005603-kjcbbgse	190	8	scores	score	NNS
cord-005603-kjcbbgse	190	9	in	in	IN
cord-005603-kjcbbgse	190	10	septic	septic	JJ
cord-005603-kjcbbgse	190	11	patients	patient	NNS
cord-005603-kjcbbgse	190	12	have	have	VBP
cord-005603-kjcbbgse	190	13	led	lead	VBN
cord-005603-kjcbbgse	190	14	to	to	IN
cord-005603-kjcbbgse	190	15	the	the	DT
cord-005603-kjcbbgse	190	16	development	development	NN
cord-005603-kjcbbgse	190	17	of	of	IN
cord-005603-kjcbbgse	190	18	customised	customised	JJ
cord-005603-kjcbbgse	190	19	scores	score	NNS
cord-005603-kjcbbgse	190	20	,	,	,
cord-005603-kjcbbgse	190	21	either	either	CC
cord-005603-kjcbbgse	190	22	through	through	IN
cord-005603-kjcbbgse	190	23	the	the	DT
cord-005603-kjcbbgse	190	24	integration	integration	NN
cord-005603-kjcbbgse	190	25	of	of	IN
cord-005603-kjcbbgse	190	26	additional	additional	JJ
cord-005603-kjcbbgse	190	27	variables	variable	NNS
cord-005603-kjcbbgse	190	28	[	[	-LRB-
cord-005603-kjcbbgse	190	29	23	23	CD
cord-005603-kjcbbgse	190	30	]	]	-RRB-
cord-005603-kjcbbgse	190	31	or	or	CC
cord-005603-kjcbbgse	190	32	through	through	IN
cord-005603-kjcbbgse	190	33	modification	modification	NN
cord-005603-kjcbbgse	190	34	of	of	IN
cord-005603-kjcbbgse	190	35	the	the	DT
cord-005603-kjcbbgse	190	36	weighting	weighting	NN
cord-005603-kjcbbgse	190	37	of	of	IN
cord-005603-kjcbbgse	190	38	variables	variable	NNS
cord-005603-kjcbbgse	190	39	included	include	VBN
cord-005603-kjcbbgse	190	40	in	in	IN
cord-005603-kjcbbgse	190	41	the	the	DT
cord-005603-kjcbbgse	190	42	original	original	JJ
cord-005603-kjcbbgse	190	43	score	score	NN
cord-005603-kjcbbgse	190	44	[	[	-LRB-
cord-005603-kjcbbgse	190	45	24	24	CD
cord-005603-kjcbbgse	190	46	]	]	-RRB-
cord-005603-kjcbbgse	190	47	.	.	.
cord-005603-kjcbbgse	191	1	The	the	DT
cord-005603-kjcbbgse	191	2	use	use	NN
cord-005603-kjcbbgse	191	3	of	of	IN
cord-005603-kjcbbgse	191	4	such	such	JJ
cord-005603-kjcbbgse	191	5	customised	customise	VBN
cord-005603-kjcbbgse	191	6	models	model	NNS
cord-005603-kjcbbgse	191	7	in	in	IN
cord-005603-kjcbbgse	191	8	risk	risk	NN
cord-005603-kjcbbgse	191	9	prediction	prediction	NN
cord-005603-kjcbbgse	191	10	in	in	IN
cord-005603-kjcbbgse	191	11	the	the	DT
cord-005603-kjcbbgse	191	12	context	context	NN
cord-005603-kjcbbgse	191	13	of	of	IN
cord-005603-kjcbbgse	191	14	clinical	clinical	JJ
cord-005603-kjcbbgse	191	15	trials	trial	NNS
cord-005603-kjcbbgse	191	16	to	to	TO
cord-005603-kjcbbgse	191	17	accurately	accurately	RB
cord-005603-kjcbbgse	191	18	compare	compare	VB
cord-005603-kjcbbgse	191	19	predicted	predict	VBN
cord-005603-kjcbbgse	191	20	to	to	IN
cord-005603-kjcbbgse	191	21	observed	observe	VBN
cord-005603-kjcbbgse	191	22	mortality	mortality	NN
cord-005603-kjcbbgse	191	23	and	and	CC
cord-005603-kjcbbgse	191	24	derive	derive	VB
cord-005603-kjcbbgse	191	25	the	the	DT
cord-005603-kjcbbgse	191	26	efficacy	efficacy	NN
cord-005603-kjcbbgse	191	27	of	of	IN
cord-005603-kjcbbgse	191	28	new	new	JJ
cord-005603-kjcbbgse	191	29	therapies	therapy	NNS
cord-005603-kjcbbgse	191	30	in	in	IN
cord-005603-kjcbbgse	191	31	subgroups	subgroup	NNS
cord-005603-kjcbbgse	191	32	of	of	IN
cord-005603-kjcbbgse	191	33	patients	patient	NNS
cord-005603-kjcbbgse	191	34	has	have	VBZ
cord-005603-kjcbbgse	191	35	,	,	,
cord-005603-kjcbbgse	191	36	however	however	RB
cord-005603-kjcbbgse	191	37	,	,	,
cord-005603-kjcbbgse	191	38	been	be	VBN
cord-005603-kjcbbgse	191	39	disappointing	disappointing	JJ
cord-005603-kjcbbgse	191	40	[	[	-LRB-
cord-005603-kjcbbgse	191	41	23	23	CD
cord-005603-kjcbbgse	191	42	,	,	,
cord-005603-kjcbbgse	191	43	25	25	CD
cord-005603-kjcbbgse	191	44	]	]	-RRB-
cord-005603-kjcbbgse	191	45	.	.	.
cord-005603-kjcbbgse	192	1	It	-PRON-	PRP
cord-005603-kjcbbgse	192	2	is	be	VBZ
cord-005603-kjcbbgse	192	3	apparent	apparent	JJ
cord-005603-kjcbbgse	192	4	that	that	IN
cord-005603-kjcbbgse	192	5	the	the	DT
cord-005603-kjcbbgse	192	6	general	general	JJ
cord-005603-kjcbbgse	192	7	scores	score	NNS
cord-005603-kjcbbgse	192	8	,	,	,
cord-005603-kjcbbgse	192	9	whether	whether	IN
cord-005603-kjcbbgse	192	10	or	or	CC
cord-005603-kjcbbgse	192	11	not	not	RB
cord-005603-kjcbbgse	192	12	customised	customise	VBN
cord-005603-kjcbbgse	192	13	,	,	,
cord-005603-kjcbbgse	192	14	principally	principally	RB
cord-005603-kjcbbgse	192	15	reflect	reflect	VBP
cord-005603-kjcbbgse	192	16	the	the	DT
cord-005603-kjcbbgse	192	17	severity	severity	NN
cord-005603-kjcbbgse	192	18	of	of	IN
cord-005603-kjcbbgse	192	19	acute	acute	JJ
cord-005603-kjcbbgse	192	20	physiologic	physiologic	JJ
cord-005603-kjcbbgse	192	21	disturbances	disturbance	NNS
cord-005603-kjcbbgse	192	22	when	when	WRB
cord-005603-kjcbbgse	192	23	measured	measure	VBN
cord-005603-kjcbbgse	192	24	at	at	IN
cord-005603-kjcbbgse	192	25	time	time	NN
cord-005603-kjcbbgse	192	26	of	of	IN
cord-005603-kjcbbgse	192	27	sepsis	sepsis	NN
cord-005603-kjcbbgse	192	28	;	;	:
cord-005603-kjcbbgse	192	29	in	in	IN
cord-005603-kjcbbgse	192	30	other	other	JJ
cord-005603-kjcbbgse	192	31	words	word	NNS
cord-005603-kjcbbgse	192	32	,	,	,
cord-005603-kjcbbgse	192	33	they	-PRON-	PRP
cord-005603-kjcbbgse	192	34	reflect	reflect	VBP
cord-005603-kjcbbgse	192	35	the	the	DT
cord-005603-kjcbbgse	192	36	severity	severity	NN
cord-005603-kjcbbgse	192	37	of	of	IN
cord-005603-kjcbbgse	192	38	organ	organ	NN
cord-005603-kjcbbgse	192	39	dysfunction	dysfunction	NN
cord-005603-kjcbbgse	192	40	associated	associate	VBN
cord-005603-kjcbbgse	192	41	with	with	IN
cord-005603-kjcbbgse	192	42	sepsis	sepsis	NN
cord-005603-kjcbbgse	192	43	.	.	.
cord-005603-kjcbbgse	193	1	Two	two	CD
cord-005603-kjcbbgse	193	2	studies	study	NNS
cord-005603-kjcbbgse	193	3	have	have	VBP
cord-005603-kjcbbgse	193	4	examined	examine	VBN
cord-005603-kjcbbgse	193	5	risk	risk	NN
cord-005603-kjcbbgse	193	6	factors	factor	NNS
cord-005603-kjcbbgse	193	7	for	for	IN
cord-005603-kjcbbgse	193	8	short	short	JJ
cord-005603-kjcbbgse	193	9	-	-	HYPH
cord-005603-kjcbbgse	193	10	term	term	NN
cord-005603-kjcbbgse	193	11	mortality	mortality	NN
cord-005603-kjcbbgse	193	12	in	in	IN
cord-005603-kjcbbgse	193	13	a	a	DT
cord-005603-kjcbbgse	193	14	predefined	predefined	JJ
cord-005603-kjcbbgse	193	15	cohort	cohort	NN
cord-005603-kjcbbgse	193	16	of	of	IN
cord-005603-kjcbbgse	193	17	ICU	ICU	NNP
cord-005603-kjcbbgse	193	18	patients	patient	NNS
cord-005603-kjcbbgse	193	19	with	with	IN
cord-005603-kjcbbgse	193	20	sepsis	sepsis	NN
cord-005603-kjcbbgse	193	21	or	or	CC
cord-005603-kjcbbgse	193	22	severe	severe	JJ
cord-005603-kjcbbgse	193	23	sepsis	sepsis	NN
cord-005603-kjcbbgse	193	24	[	[	-LRB-
cord-005603-kjcbbgse	193	25	13	13	CD
cord-005603-kjcbbgse	193	26	,	,	,
cord-005603-kjcbbgse	193	27	17	17	CD
cord-005603-kjcbbgse	193	28	]	]	-RRB-
cord-005603-kjcbbgse	193	29	.	.	.
cord-005603-kjcbbgse	194	1	In	in	IN
cord-005603-kjcbbgse	194	2	the	the	DT
cord-005603-kjcbbgse	194	3	French	french	JJ
cord-005603-kjcbbgse	194	4	multicenter	multicenter	JJ
cord-005603-kjcbbgse	194	5	study	study	NN
cord-005603-kjcbbgse	194	6	[	[	-LRB-
cord-005603-kjcbbgse	194	7	13	13	CD
cord-005603-kjcbbgse	194	8	]	]	-RRB-
cord-005603-kjcbbgse	194	9	several	several	JJ
cord-005603-kjcbbgse	194	10	factors	factor	NNS
cord-005603-kjcbbgse	194	11	recorded	record	VBN
cord-005603-kjcbbgse	194	12	at	at	IN
cord-005603-kjcbbgse	194	13	onset	onset	NN
cord-005603-kjcbbgse	194	14	of	of	IN
cord-005603-kjcbbgse	194	15	sepsis	sepsis	NN
cord-005603-kjcbbgse	194	16	were	be	VBD
cord-005603-kjcbbgse	194	17	found	find	VBN
cord-005603-kjcbbgse	194	18	associated	associate	VBN
cord-005603-kjcbbgse	194	19	with	with	IN
cord-005603-kjcbbgse	194	20	early	early	JJ
cord-005603-kjcbbgse	194	21	mortality	mortality	NN
cord-005603-kjcbbgse	194	22	of	of	IN
cord-005603-kjcbbgse	194	23	patients	patient	NNS
cord-005603-kjcbbgse	194	24	with	with	IN
cord-005603-kjcbbgse	194	25	severe	severe	JJ
cord-005603-kjcbbgse	194	26	sepsis	sepsis	NN
cord-005603-kjcbbgse	194	27	:	:	:
cord-005603-kjcbbgse	194	28	the	the	DT
cord-005603-kjcbbgse	194	29	MacCabe	MacCabe	NNP
cord-005603-kjcbbgse	194	30	index	index	NN
cord-005603-kjcbbgse	194	31	(	(	-LRB-
cord-005603-kjcbbgse	194	32	OR	or	CC
cord-005603-kjcbbgse	194	33	=	=	SYM
cord-005603-kjcbbgse	194	34	1.5	1.5	CD
cord-005603-kjcbbgse	194	35	and	and	CC
cord-005603-kjcbbgse	194	36	2	2	CD
cord-005603-kjcbbgse	194	37	for	for	IN
cord-005603-kjcbbgse	194	38	ultimately	ultimately	RB
cord-005603-kjcbbgse	194	39	and	and	CC
cord-005603-kjcbbgse	194	40	rapidly	rapidly	RB
cord-005603-kjcbbgse	194	41	fatal	fatal	JJ
cord-005603-kjcbbgse	194	42	underlying	underlying	JJ
cord-005603-kjcbbgse	194	43	disease	disease	NN
cord-005603-kjcbbgse	194	44	,	,	,
cord-005603-kjcbbgse	194	45	respectively	respectively	RB
cord-005603-kjcbbgse	194	46	)	)	-RRB-
cord-005603-kjcbbgse	194	47	,	,	,
cord-005603-kjcbbgse	194	48	and	and	CC
cord-005603-kjcbbgse	194	49	bacteraemia	bacteraemia	NNP
cord-005603-kjcbbgse	194	50	(	(	-LRB-
cord-005603-kjcbbgse	194	51	OR	or	CC
cord-005603-kjcbbgse	194	52	=	=	SYM
cord-005603-kjcbbgse	194	53	1.7	1.7	CD
cord-005603-kjcbbgse	194	54	)	)	-RRB-
cord-005603-kjcbbgse	194	55	;	;	:
cord-005603-kjcbbgse	194	56	however	however	RB
cord-005603-kjcbbgse	194	57	,	,	,
cord-005603-kjcbbgse	194	58	the	the	DT
cord-005603-kjcbbgse	194	59	three	three	CD
cord-005603-kjcbbgse	194	60	most	most	RBS
cord-005603-kjcbbgse	194	61	important	important	JJ
cord-005603-kjcbbgse	194	62	independent	independent	JJ
cord-005603-kjcbbgse	194	63	risk	risk	NN
cord-005603-kjcbbgse	194	64	factors	factor	NNS
cord-005603-kjcbbgse	194	65	for	for	IN
cord-005603-kjcbbgse	194	66	early	early	JJ
cord-005603-kjcbbgse	194	67	mortality	mortality	NN
cord-005603-kjcbbgse	194	68	were	be	VBD
cord-005603-kjcbbgse	194	69	the	the	DT
cord-005603-kjcbbgse	194	70	SAPS	SAPS	NNP
cord-005603-kjcbbgse	194	71	II	II	NNP
cord-005603-kjcbbgse	194	72	(	(	-LRB-
cord-005603-kjcbbgse	194	73	OR	or	CC
cord-005603-kjcbbgse	194	74	=	=	SYM
cord-005603-kjcbbgse	194	75	1.03	1.03	CD
cord-005603-kjcbbgse	194	76	per	per	IN
cord-005603-kjcbbgse	194	77	unit	unit	NN
cord-005603-kjcbbgse	194	78	of	of	IN
cord-005603-kjcbbgse	194	79	score	score	NN
cord-005603-kjcbbgse	194	80	,	,	,
cord-005603-kjcbbgse	194	81	P	p	NN
cord-005603-kjcbbgse	194	82	=	=	SYM
cord-005603-kjcbbgse	194	83	0.003	0.003	CD
cord-005603-kjcbbgse	194	84	)	)	-RRB-
cord-005603-kjcbbgse	194	85	,	,	,
cord-005603-kjcbbgse	194	86	the	the	DT
cord-005603-kjcbbgse	194	87	presence	presence	NN
cord-005603-kjcbbgse	194	88	of	of	IN
cord-005603-kjcbbgse	194	89	shock	shock	NN
cord-005603-kjcbbgse	194	90	(	(	-LRB-
cord-005603-kjcbbgse	194	91	OR	or	CC
cord-005603-kjcbbgse	194	92	=	=	SYM
cord-005603-kjcbbgse	194	93	2.9	2.9	CD
cord-005603-kjcbbgse	194	94	,	,	,
cord-005603-kjcbbgse	194	95	P	p	NN
cord-005603-kjcbbgse	194	96	=	=	SYM
cord-005603-kjcbbgse	194	97	0.01	0.01	CD
cord-005603-kjcbbgse	194	98	)	)	-RRB-
cord-005603-kjcbbgse	194	99	,	,	,
cord-005603-kjcbbgse	194	100	and	and	CC
cord-005603-kjcbbgse	194	101	the	the	DT
cord-005603-kjcbbgse	194	102	presence	presence	NN
cord-005603-kjcbbgse	194	103	of	of	IN
cord-005603-kjcbbgse	194	104	more	more	JJR
cord-005603-kjcbbgse	194	105	than	than	IN
cord-005603-kjcbbgse	194	106	one	one	CD
cord-005603-kjcbbgse	194	107	organ	organ	NN
cord-005603-kjcbbgse	194	108	system	system	NN
cord-005603-kjcbbgse	194	109	failures	failure	NNS
cord-005603-kjcbbgse	194	110	,	,	,
cord-005603-kjcbbgse	194	111	as	as	IN
cord-005603-kjcbbgse	194	112	defined	define	VBN
cord-005603-kjcbbgse	194	113	according	accord	VBG
cord-005603-kjcbbgse	194	114	to	to	IN
cord-005603-kjcbbgse	194	115	Knaus	Knaus	NNP
cord-005603-kjcbbgse	194	116	et	et	NNP
cord-005603-kjcbbgse	194	117	al	al	NNP
cord-005603-kjcbbgse	194	118	.	.	.
cord-005603-kjcbbgse	195	1	[	[	-LRB-
cord-005603-kjcbbgse	195	2	26	26	CD
cord-005603-kjcbbgse	195	3	]	]	-RRB-
cord-005603-kjcbbgse	196	1	(	(	-LRB-
cord-005603-kjcbbgse	196	2	OR	or	CC
cord-005603-kjcbbgse	196	3	=	=	SYM
cord-005603-kjcbbgse	196	4	8.4	8.4	CD
cord-005603-kjcbbgse	196	5	and	and	CC
cord-005603-kjcbbgse	196	6	OR	or	NN
cord-005603-kjcbbgse	196	7	=	=	SYM
cord-005603-kjcbbgse	196	8	9.4	9.4	CD
cord-005603-kjcbbgse	196	9	for	for	IN
cord-005603-kjcbbgse	196	10	2	2	CD
cord-005603-kjcbbgse	196	11	or	or	CC
cord-005603-kjcbbgse	196	12	>	>	XX
cord-005603-kjcbbgse	196	13	3	3	CD
cord-005603-kjcbbgse	196	14	organ	organ	NN
cord-005603-kjcbbgse	196	15	failures	failure	NNS
cord-005603-kjcbbgse	196	16	,	,	,
cord-005603-kjcbbgse	196	17	respectively	respectively	RB
cord-005603-kjcbbgse	196	18	;	;	:
cord-005603-kjcbbgse	196	19	P	p	NN
cord-005603-kjcbbgse	196	20	=	=	SYM
cord-005603-kjcbbgse	196	21	0.002	0.002	CD
cord-005603-kjcbbgse	196	22	)	)	-RRB-
cord-005603-kjcbbgse	196	23	.	.	.
cord-005603-kjcbbgse	197	1	Later	later	RB
cord-005603-kjcbbgse	197	2	mortality	mortality	NN
cord-005603-kjcbbgse	197	3	after	after	IN
cord-005603-kjcbbgse	197	4	severe	severe	JJ
cord-005603-kjcbbgse	197	5	sepsis	sepsis	NN
cord-005603-kjcbbgse	197	6	was	be	VBD
cord-005603-kjcbbgse	197	7	also	also	RB
cord-005603-kjcbbgse	197	8	associated	associate	VBN
cord-005603-kjcbbgse	197	9	with	with	IN
cord-005603-kjcbbgse	197	10	the	the	DT
cord-005603-kjcbbgse	197	11	SAPS	SAPS	NNP
cord-005603-kjcbbgse	197	12	II	II	NNP
cord-005603-kjcbbgse	197	13	,	,	,
cord-005603-kjcbbgse	197	14	and	and	CC
cord-005603-kjcbbgse	197	15	the	the	DT
cord-005603-kjcbbgse	197	16	number	number	NN
cord-005603-kjcbbgse	197	17	of	of	IN
cord-005603-kjcbbgse	197	18	organ	organ	NN
cord-005603-kjcbbgse	197	19	system	system	NN
cord-005603-kjcbbgse	197	20	failures	failure	NNS
cord-005603-kjcbbgse	197	21	,	,	,
cord-005603-kjcbbgse	197	22	but	but	CC
cord-005603-kjcbbgse	197	23	also	also	RB
cord-005603-kjcbbgse	197	24	with	with	IN
cord-005603-kjcbbgse	197	25	other	other	JJ
cord-005603-kjcbbgse	197	26	factors	factor	NNS
cord-005603-kjcbbgse	197	27	related	relate	VBN
cord-005603-kjcbbgse	197	28	to	to	IN
cord-005603-kjcbbgse	197	29	underlying	underlie	VBG
cord-005603-kjcbbgse	197	30	diseases	disease	NNS
cord-005603-kjcbbgse	197	31	,	,	,
cord-005603-kjcbbgse	197	32	such	such	JJ
cord-005603-kjcbbgse	197	33	as	as	IN
cord-005603-kjcbbgse	197	34	pre	pre	JJ
cord-005603-kjcbbgse	197	35	-	-	JJ
cord-005603-kjcbbgse	197	36	existing	existing	JJ
cord-005603-kjcbbgse	197	37	liver	liver	NN
cord-005603-kjcbbgse	197	38	or	or	CC
cord-005603-kjcbbgse	197	39	cardiovascular	cardiovascular	JJ
cord-005603-kjcbbgse	197	40	failure	failure	NN
cord-005603-kjcbbgse	197	41	or	or	CC
cord-005603-kjcbbgse	197	42	the	the	DT
cord-005603-kjcbbgse	197	43	MacCabe	MacCabe	NNP
cord-005603-kjcbbgse	197	44	index	index	NN
cord-005603-kjcbbgse	197	45	,	,	,
cord-005603-kjcbbgse	197	46	the	the	DT
cord-005603-kjcbbgse	197	47	admission	admission	NN
cord-005603-kjcbbgse	197	48	category	category	NN
cord-005603-kjcbbgse	197	49	,	,	,
cord-005603-kjcbbgse	197	50	and	and	CC
cord-005603-kjcbbgse	197	51	presence	presence	NN
cord-005603-kjcbbgse	197	52	of	of	IN
cord-005603-kjcbbgse	197	53	multiple	multiple	JJ
cord-005603-kjcbbgse	197	54	sources	source	NNS
cord-005603-kjcbbgse	197	55	of	of	IN
cord-005603-kjcbbgse	197	56	infection	infection	NN
cord-005603-kjcbbgse	197	57	.	.	.
cord-005603-kjcbbgse	198	1	In	in	IN
cord-005603-kjcbbgse	198	2	176	176	CD
cord-005603-kjcbbgse	198	3	patients	patient	NNS
cord-005603-kjcbbgse	198	4	with	with	IN
cord-005603-kjcbbgse	198	5	bacteraemic	bacteraemic	NNP
cord-005603-kjcbbgse	198	6	sepsis	sepsis	NN
cord-005603-kjcbbgse	198	7	,	,	,
cord-005603-kjcbbgse	198	8	Pittet	Pittet	NNP
cord-005603-kjcbbgse	198	9	et	et	FW
cord-005603-kjcbbgse	198	10	al	al	NNP
cord-005603-kjcbbgse	198	11	.	.	.
cord-005603-kjcbbgse	199	1	[	[	-LRB-
cord-005603-kjcbbgse	199	2	17	17	CD
cord-005603-kjcbbgse	199	3	]	]	-RRB-
cord-005603-kjcbbgse	199	4	also	also	RB
cord-005603-kjcbbgse	199	5	found	find	VBD
cord-005603-kjcbbgse	199	6	that	that	IN
cord-005603-kjcbbgse	199	7	the	the	DT
cord-005603-kjcbbgse	199	8	APACHE	APACHE	NNP
cord-005603-kjcbbgse	199	9	II	II	NNP
cord-005603-kjcbbgse	199	10	score	score	NN
cord-005603-kjcbbgse	199	11	measured	measure	VBN
cord-005603-kjcbbgse	199	12	at	at	IN
cord-005603-kjcbbgse	199	13	the	the	DT
cord-005603-kjcbbgse	199	14	time	time	NN
cord-005603-kjcbbgse	199	15	of	of	IN
cord-005603-kjcbbgse	199	16	sepsis	sepsis	NN
cord-005603-kjcbbgse	199	17	was	be	VBD
cord-005603-kjcbbgse	199	18	highly	highly	RB
cord-005603-kjcbbgse	199	19	predictive	predictive	JJ
cord-005603-kjcbbgse	199	20	of	of	IN
cord-005603-kjcbbgse	199	21	mortality	mortality	NN
cord-005603-kjcbbgse	199	22	(	(	-LRB-
cord-005603-kjcbbgse	199	23	and	and	CC
cord-005603-kjcbbgse	199	24	a	a	DT
cord-005603-kjcbbgse	199	25	better	well	JJR
cord-005603-kjcbbgse	199	26	predictor	predictor	NN
cord-005603-kjcbbgse	199	27	than	than	IN
cord-005603-kjcbbgse	199	28	APACHE	APACHE	NNP
cord-005603-kjcbbgse	199	29	II	II	NNP
cord-005603-kjcbbgse	199	30	measured	measure	VBN
cord-005603-kjcbbgse	199	31	on	on	IN
cord-005603-kjcbbgse	199	32	ICU	ICU	NNP
cord-005603-kjcbbgse	199	33	admission	admission	NN
cord-005603-kjcbbgse	199	34	)	)	-RRB-
cord-005603-kjcbbgse	199	35	.	.	.
cord-005603-kjcbbgse	200	1	These	these	DT
cord-005603-kjcbbgse	200	2	authors	author	NNS
cord-005603-kjcbbgse	200	3	also	also	RB
cord-005603-kjcbbgse	200	4	noted	note	VBD
cord-005603-kjcbbgse	200	5	that	that	IN
cord-005603-kjcbbgse	200	6	prior	prior	JJ
cord-005603-kjcbbgse	200	7	antimicrobial	antimicrobial	JJ
cord-005603-kjcbbgse	200	8	therapy	therapy	NN
cord-005603-kjcbbgse	200	9	and	and	CC
cord-005603-kjcbbgse	200	10	hypothermia	hypothermia	NN
cord-005603-kjcbbgse	200	11	were	be	VBD
cord-005603-kjcbbgse	200	12	associated	associate	VBN
cord-005603-kjcbbgse	200	13	with	with	IN
cord-005603-kjcbbgse	200	14	a	a	DT
cord-005603-kjcbbgse	200	15	poorer	poor	JJR
cord-005603-kjcbbgse	200	16	prognosis	prognosis	NN
cord-005603-kjcbbgse	200	17	.	.	.
cord-005603-kjcbbgse	201	1	Organ	organ	NN
cord-005603-kjcbbgse	201	2	dysfunctions	dysfunction	NNS
cord-005603-kjcbbgse	201	3	were	be	VBD
cord-005603-kjcbbgse	201	4	also	also	RB
cord-005603-kjcbbgse	201	5	strongly	strongly	RB
cord-005603-kjcbbgse	201	6	associated	associate	VBN
cord-005603-kjcbbgse	201	7	with	with	IN
cord-005603-kjcbbgse	201	8	mortality	mortality	NN
cord-005603-kjcbbgse	201	9	;	;	:
cord-005603-kjcbbgse	201	10	however	however	RB
cord-005603-kjcbbgse	201	11	,	,	,
cord-005603-kjcbbgse	201	12	only	only	RB
cord-005603-kjcbbgse	201	13	those	those	DT
cord-005603-kjcbbgse	201	14	recorded	record	VBN
cord-005603-kjcbbgse	201	15	after	after	IN
cord-005603-kjcbbgse	201	16	the	the	DT
cord-005603-kjcbbgse	201	17	onset	onset	NN
cord-005603-kjcbbgse	201	18	of	of	IN
cord-005603-kjcbbgse	201	19	sepsis	sepsis	NN
cord-005603-kjcbbgse	201	20	were	be	VBD
cord-005603-kjcbbgse	201	21	associated	associate	VBN
cord-005603-kjcbbgse	201	22	with	with	IN
cord-005603-kjcbbgse	201	23	mortality	mortality	NN
cord-005603-kjcbbgse	201	24	in	in	IN
cord-005603-kjcbbgse	201	25	that	that	DT
cord-005603-kjcbbgse	201	26	study	study	NN
cord-005603-kjcbbgse	201	27	[	[	-LRB-
cord-005603-kjcbbgse	201	28	17	17	CD
cord-005603-kjcbbgse	201	29	]	]	-RRB-
cord-005603-kjcbbgse	201	30	.	.	.
cord-005603-kjcbbgse	202	1	This	this	DT
cord-005603-kjcbbgse	202	2	surprising	surprising	JJ
cord-005603-kjcbbgse	202	3	finding	finding	NN
cord-005603-kjcbbgse	202	4	may	may	MD
cord-005603-kjcbbgse	202	5	have	have	VB
cord-005603-kjcbbgse	202	6	been	be	VBN
cord-005603-kjcbbgse	202	7	due	due	JJ
cord-005603-kjcbbgse	202	8	to	to	IN
cord-005603-kjcbbgse	202	9	the	the	DT
cord-005603-kjcbbgse	202	10	limited	limited	JJ
cord-005603-kjcbbgse	202	11	power	power	NN
cord-005603-kjcbbgse	202	12	of	of	IN
cord-005603-kjcbbgse	202	13	the	the	DT
cord-005603-kjcbbgse	202	14	study	study	NN
cord-005603-kjcbbgse	202	15	.	.	.
cord-005603-kjcbbgse	203	1	Therefore	therefore	RB
cord-005603-kjcbbgse	203	2	,	,	,
cord-005603-kjcbbgse	203	3	in	in	IN
cord-005603-kjcbbgse	203	4	addition	addition	NN
cord-005603-kjcbbgse	203	5	to	to	IN
cord-005603-kjcbbgse	203	6	a	a	DT
cord-005603-kjcbbgse	203	7	general	general	JJ
cord-005603-kjcbbgse	203	8	severity	severity	NN
cord-005603-kjcbbgse	203	9	score	score	NN
cord-005603-kjcbbgse	203	10	,	,	,
cord-005603-kjcbbgse	203	11	and	and	CC
cord-005603-kjcbbgse	203	12	one	one	CD
cord-005603-kjcbbgse	203	13	assessing	assess	VBG
cord-005603-kjcbbgse	203	14	prior	prior	JJ
cord-005603-kjcbbgse	203	15	comorbidities	comorbiditie	NNS
cord-005603-kjcbbgse	203	16	such	such	JJ
cord-005603-kjcbbgse	203	17	as	as	IN
cord-005603-kjcbbgse	203	18	the	the	DT
cord-005603-kjcbbgse	203	19	Mac	Mac	NNP
cord-005603-kjcbbgse	203	20	-	-	HYPH
cord-005603-kjcbbgse	203	21	Cabe	Cabe	NNP
cord-005603-kjcbbgse	203	22	score	score	NN
cord-005603-kjcbbgse	203	23	,	,	,
cord-005603-kjcbbgse	203	24	organ	organ	NN
cord-005603-kjcbbgse	203	25	dysfunctions	dysfunction	NNS
cord-005603-kjcbbgse	203	26	at	at	IN
cord-005603-kjcbbgse	203	27	onset	onset	NN
cord-005603-kjcbbgse	203	28	of	of	IN
cord-005603-kjcbbgse	203	29	sepsis	sepsis	NN
cord-005603-kjcbbgse	203	30	and	and	CC
cord-005603-kjcbbgse	203	31	developing	develop	VBG
cord-005603-kjcbbgse	203	32	after	after	IN
cord-005603-kjcbbgse	203	33	its	-PRON-	PRP$
cord-005603-kjcbbgse	203	34	onset	onset	NN
cord-005603-kjcbbgse	203	35	appear	appear	VBP
cord-005603-kjcbbgse	203	36	as	as	IN
cord-005603-kjcbbgse	203	37	the	the	DT
cord-005603-kjcbbgse	203	38	major	major	JJ
cord-005603-kjcbbgse	203	39	determinants	determinant	NNS
cord-005603-kjcbbgse	203	40	of	of	IN
cord-005603-kjcbbgse	203	41	the	the	DT
cord-005603-kjcbbgse	203	42	short	short	JJ
cord-005603-kjcbbgse	203	43	-	-	HYPH
cord-005603-kjcbbgse	203	44	term	term	NN
cord-005603-kjcbbgse	203	45	outcome	outcome	NN
cord-005603-kjcbbgse	203	46	of	of	IN
cord-005603-kjcbbgse	203	47	septic	septic	JJ
cord-005603-kjcbbgse	203	48	patients	patient	NNS
cord-005603-kjcbbgse	203	49	.	.	.
cord-005603-kjcbbgse	204	1	Whether	whether	IN
cord-005603-kjcbbgse	204	2	customised	customised	JJ
cord-005603-kjcbbgse	204	3	models	model	NNS
cord-005603-kjcbbgse	204	4	for	for	IN
cord-005603-kjcbbgse	204	5	sepsis	sepsis	NN
cord-005603-kjcbbgse	204	6	perform	perform	VBP
cord-005603-kjcbbgse	204	7	better	well	RBR
cord-005603-kjcbbgse	204	8	than	than	IN
cord-005603-kjcbbgse	204	9	the	the	DT
cord-005603-kjcbbgse	204	10	above	above	JJ
cord-005603-kjcbbgse	204	11	combination	combination	NN
cord-005603-kjcbbgse	204	12	of	of	IN
cord-005603-kjcbbgse	204	13	three	three	CD
cord-005603-kjcbbgse	204	14	major	major	JJ
cord-005603-kjcbbgse	204	15	determinants	determinant	NNS
cord-005603-kjcbbgse	204	16	has	have	VBZ
cord-005603-kjcbbgse	204	17	not	not	RB
cord-005603-kjcbbgse	204	18	been	be	VBN
cord-005603-kjcbbgse	204	19	formally	formally	RB
cord-005603-kjcbbgse	204	20	tested	test	VBN
cord-005603-kjcbbgse	204	21	on	on	IN
cord-005603-kjcbbgse	204	22	a	a	DT
cord-005603-kjcbbgse	204	23	large	large	JJ
cord-005603-kjcbbgse	204	24	cohort	cohort	NN
cord-005603-kjcbbgse	204	25	of	of	IN
cord-005603-kjcbbgse	204	26	patients	patient	NNS
cord-005603-kjcbbgse	204	27	,	,	,
cord-005603-kjcbbgse	204	28	and	and	CC
cord-005603-kjcbbgse	204	29	remains	remain	VBZ
cord-005603-kjcbbgse	204	30	unknown	unknown	JJ
cord-005603-kjcbbgse	204	31	.	.	.
cord-005603-kjcbbgse	205	1	An	an	DT
cord-005603-kjcbbgse	205	2	interesting	interesting	JJ
cord-005603-kjcbbgse	205	3	approach	approach	NN
cord-005603-kjcbbgse	205	4	would	would	MD
cord-005603-kjcbbgse	205	5	be	be	VB
cord-005603-kjcbbgse	205	6	to	to	TO
cord-005603-kjcbbgse	205	7	incorporate	incorporate	VB
cord-005603-kjcbbgse	205	8	a	a	DT
cord-005603-kjcbbgse	205	9	score	score	NN
cord-005603-kjcbbgse	205	10	of	of	IN
cord-005603-kjcbbgse	205	11	organ	organ	NN
cord-005603-kjcbbgse	205	12	dysfunction	dysfunction	NN
cord-005603-kjcbbgse	205	13	in	in	IN
cord-005603-kjcbbgse	205	14	the	the	DT
cord-005603-kjcbbgse	205	15	prognostic	prognostic	JJ
cord-005603-kjcbbgse	205	16	assessment	assessment	NN
cord-005603-kjcbbgse	205	17	of	of	IN
cord-005603-kjcbbgse	205	18	patients	patient	NNS
cord-005603-kjcbbgse	205	19	with	with	IN
cord-005603-kjcbbgse	205	20	sepsis	sepsis	NN
cord-005603-kjcbbgse	205	21	.	.	.
cord-005603-kjcbbgse	206	1	These	these	DT
cord-005603-kjcbbgse	206	2	refined	refined	JJ
cord-005603-kjcbbgse	206	3	scoring	scoring	NN
cord-005603-kjcbbgse	206	4	systems	system	NNS
cord-005603-kjcbbgse	206	5	for	for	IN
cord-005603-kjcbbgse	206	6	organ	organ	NN
cord-005603-kjcbbgse	206	7	dysfunction	dysfunction	NN
cord-005603-kjcbbgse	206	8	/	/	SYM
cord-005603-kjcbbgse	206	9	failures	failure	NNS
cord-005603-kjcbbgse	206	10	[	[	-LRB-
cord-005603-kjcbbgse	206	11	27	27	CD
cord-005603-kjcbbgse	206	12	,	,	,
cord-005603-kjcbbgse	206	13	28	28	CD
cord-005603-kjcbbgse	206	14	,	,	,
cord-005603-kjcbbgse	206	15	29	29	CD
cord-005603-kjcbbgse	206	16	]	]	-RRB-
cord-005603-kjcbbgse	206	17	which	which	WDT
cord-005603-kjcbbgse	206	18	allows	allow	VBZ
cord-005603-kjcbbgse	206	19	identification	identification	NN
cord-005603-kjcbbgse	206	20	of	of	IN
cord-005603-kjcbbgse	206	21	organ	organ	NN
cord-005603-kjcbbgse	206	22	dysfunction	dysfunction	NN
cord-005603-kjcbbgse	206	23	in	in	IN
cord-005603-kjcbbgse	206	24	a	a	DT
cord-005603-kjcbbgse	206	25	graded	grade	VBN
cord-005603-kjcbbgse	206	26	manner	manner	NN
cord-005603-kjcbbgse	206	27	and	and	CC
cord-005603-kjcbbgse	206	28	at	at	IN
cord-005603-kjcbbgse	206	29	an	an	DT
cord-005603-kjcbbgse	206	30	earlier	early	JJR
cord-005603-kjcbbgse	206	31	stage	stage	NN
cord-005603-kjcbbgse	206	32	,	,	,
cord-005603-kjcbbgse	206	33	would	would	MD
cord-005603-kjcbbgse	206	34	likely	likely	RB
cord-005603-kjcbbgse	206	35	allow	allow	VB
cord-005603-kjcbbgse	206	36	a	a	DT
cord-005603-kjcbbgse	206	37	more	more	RBR
cord-005603-kjcbbgse	206	38	precise	precise	JJ
cord-005603-kjcbbgse	206	39	description	description	NN
cord-005603-kjcbbgse	206	40	of	of	IN
cord-005603-kjcbbgse	206	41	prognostic	prognostic	JJ
cord-005603-kjcbbgse	206	42	factors	factor	NNS
cord-005603-kjcbbgse	206	43	and	and	CC
cord-005603-kjcbbgse	206	44	of	of	IN
cord-005603-kjcbbgse	206	45	the	the	DT
cord-005603-kjcbbgse	206	46	interrelations	interrelation	NNS
cord-005603-kjcbbgse	206	47	between	between	IN
cord-005603-kjcbbgse	206	48	the	the	DT
cord-005603-kjcbbgse	206	49	various	various	JJ
cord-005603-kjcbbgse	206	50	organ	organ	NN
cord-005603-kjcbbgse	206	51	dysfunctions	dysfunction	NNS
cord-005603-kjcbbgse	206	52	and	and	CC
cord-005603-kjcbbgse	206	53	their	-PRON-	PRP$
cord-005603-kjcbbgse	206	54	respective	respective	JJ
cord-005603-kjcbbgse	206	55	impact	impact	NN
cord-005603-kjcbbgse	206	56	on	on	IN
cord-005603-kjcbbgse	206	57	outcome	outcome	NN
cord-005603-kjcbbgse	206	58	.	.	.
cord-005603-kjcbbgse	207	1	However	however	RB
cord-005603-kjcbbgse	207	2	,	,	,
cord-005603-kjcbbgse	207	3	from	from	IN
cord-005603-kjcbbgse	207	4	the	the	DT
cord-005603-kjcbbgse	207	5	viewpoint	viewpoint	NN
cord-005603-kjcbbgse	207	6	of	of	IN
cord-005603-kjcbbgse	207	7	mortality	mortality	NN
cord-005603-kjcbbgse	207	8	prediction	prediction	NN
cord-005603-kjcbbgse	207	9	,	,	,
cord-005603-kjcbbgse	207	10	it	-PRON-	PRP
cord-005603-kjcbbgse	207	11	is	be	VBZ
cord-005603-kjcbbgse	207	12	unlikely	unlikely	JJ
cord-005603-kjcbbgse	207	13	that	that	IN
cord-005603-kjcbbgse	207	14	these	these	DT
cord-005603-kjcbbgse	207	15	scores	score	NNS
cord-005603-kjcbbgse	207	16	perform	perform	VBP
cord-005603-kjcbbgse	207	17	better	well	JJR
cord-005603-kjcbbgse	207	18	than	than	IN
cord-005603-kjcbbgse	207	19	the	the	DT
cord-005603-kjcbbgse	207	20	general	general	JJ
cord-005603-kjcbbgse	207	21	(	(	-LRB-
cord-005603-kjcbbgse	207	22	or	or	CC
cord-005603-kjcbbgse	207	23	customised	customise	VBN
cord-005603-kjcbbgse	207	24	)	)	-RRB-
cord-005603-kjcbbgse	207	25	scoring	score	VBG
cord-005603-kjcbbgse	207	26	systems	system	NNS
cord-005603-kjcbbgse	207	27	.	.	.
cord-005603-kjcbbgse	208	1	Most	Most	JJS
cord-005603-kjcbbgse	208	2	studies	study	NNS
cord-005603-kjcbbgse	208	3	and	and	CC
cord-005603-kjcbbgse	208	4	clinical	clinical	JJ
cord-005603-kjcbbgse	208	5	trials	trial	NNS
cord-005603-kjcbbgse	208	6	have	have	VBP
cord-005603-kjcbbgse	208	7	focused	focus	VBN
cord-005603-kjcbbgse	208	8	on	on	IN
cord-005603-kjcbbgse	208	9	28-day	28-day	CD
cord-005603-kjcbbgse	208	10	or	or	CC
cord-005603-kjcbbgse	208	11	hospital	hospital	NN
cord-005603-kjcbbgse	208	12	mortality	mortality	NN
cord-005603-kjcbbgse	208	13	,	,	,
cord-005603-kjcbbgse	208	14	a	a	DT
cord-005603-kjcbbgse	208	15	relatively	relatively	RB
cord-005603-kjcbbgse	208	16	short	short	JJ
cord-005603-kjcbbgse	208	17	-	-	HYPH
cord-005603-kjcbbgse	208	18	term	term	NN
cord-005603-kjcbbgse	208	19	view	view	NN
cord-005603-kjcbbgse	208	20	,	,	,
cord-005603-kjcbbgse	208	21	which	which	WDT
cord-005603-kjcbbgse	208	22	does	do	VBZ
cord-005603-kjcbbgse	208	23	not	not	RB
cord-005603-kjcbbgse	208	24	provide	provide	VB
cord-005603-kjcbbgse	208	25	a	a	DT
cord-005603-kjcbbgse	208	26	complete	complete	JJ
cord-005603-kjcbbgse	208	27	picture	picture	NN
cord-005603-kjcbbgse	208	28	of	of	IN
cord-005603-kjcbbgse	208	29	the	the	DT
cord-005603-kjcbbgse	208	30	impact	impact	NN
cord-005603-kjcbbgse	208	31	of	of	IN
cord-005603-kjcbbgse	208	32	sepsis	sepsis	NN
cord-005603-kjcbbgse	208	33	on	on	IN
cord-005603-kjcbbgse	208	34	life	life	NN
cord-005603-kjcbbgse	208	35	expectancy	expectancy	NN
cord-005603-kjcbbgse	208	36	,	,	,
cord-005603-kjcbbgse	208	37	an	an	DT
cord-005603-kjcbbgse	208	38	important	important	JJ
cord-005603-kjcbbgse	208	39	consideration	consideration	NN
cord-005603-kjcbbgse	208	40	for	for	IN
cord-005603-kjcbbgse	208	41	cost	cost	NN
cord-005603-kjcbbgse	208	42	-	-	HYPH
cord-005603-kjcbbgse	208	43	benefit	benefit	NN
cord-005603-kjcbbgse	208	44	studies	study	NNS
cord-005603-kjcbbgse	208	45	of	of	IN
cord-005603-kjcbbgse	208	46	the	the	DT
cord-005603-kjcbbgse	208	47	impact	impact	NN
cord-005603-kjcbbgse	208	48	of	of	IN
cord-005603-kjcbbgse	208	49	new	new	JJ
cord-005603-kjcbbgse	208	50	therapies	therapy	NNS
cord-005603-kjcbbgse	208	51	.	.	.
cord-005603-kjcbbgse	209	1	Admittedly	admittedly	RB
cord-005603-kjcbbgse	209	2	,	,	,
cord-005603-kjcbbgse	209	3	most	most	JJS
cord-005603-kjcbbgse	209	4	deaths	death	NNS
cord-005603-kjcbbgse	209	5	usually	usually	RB
cord-005603-kjcbbgse	209	6	occur	occur	VBP
cord-005603-kjcbbgse	209	7	early	early	RB
cord-005603-kjcbbgse	209	8	in	in	IN
cord-005603-kjcbbgse	209	9	severe	severe	JJ
cord-005603-kjcbbgse	209	10	sepsis	sepsis	NN
cord-005603-kjcbbgse	209	11	.	.	.
cord-005603-kjcbbgse	210	1	For	for	IN
cord-005603-kjcbbgse	210	2	example	example	NN
cord-005603-kjcbbgse	210	3	,	,	,
cord-005603-kjcbbgse	210	4	77	77	CD
cord-005603-kjcbbgse	210	5	%	%	NN
cord-005603-kjcbbgse	210	6	and	and	CC
cord-005603-kjcbbgse	210	7	71	71	CD
cord-005603-kjcbbgse	210	8	%	%	NN
cord-005603-kjcbbgse	210	9	of	of	IN
cord-005603-kjcbbgse	210	10	all	all	DT
cord-005603-kjcbbgse	210	11	deaths	death	NNS
cord-005603-kjcbbgse	210	12	had	have	VBD
cord-005603-kjcbbgse	210	13	occurred	occur	VBN
cord-005603-kjcbbgse	210	14	by	by	IN
cord-005603-kjcbbgse	210	15	day	day	NN
cord-005603-kjcbbgse	210	16	14	14	CD
cord-005603-kjcbbgse	210	17	and	and	CC
cord-005603-kjcbbgse	210	18	by	by	IN
cord-005603-kjcbbgse	210	19	day	day	NN
cord-005603-kjcbbgse	210	20	21	21	CD
cord-005603-kjcbbgse	210	21	,	,	,
cord-005603-kjcbbgse	210	22	respectively	respectively	RB
cord-005603-kjcbbgse	210	23	,	,	,
cord-005603-kjcbbgse	210	24	in	in	IN
cord-005603-kjcbbgse	210	25	the	the	DT
cord-005603-kjcbbgse	210	26	French	french	JJ
cord-005603-kjcbbgse	210	27	multicenter	multicenter	JJ
cord-005603-kjcbbgse	210	28	study	study	NN
cord-005603-kjcbbgse	210	29	[	[	-LRB-
cord-005603-kjcbbgse	210	30	13	13	CD
cord-005603-kjcbbgse	210	31	]	]	-RRB-
cord-005603-kjcbbgse	210	32	and	and	CC
cord-005603-kjcbbgse	210	33	in	in	IN
cord-005603-kjcbbgse	210	34	the	the	DT
cord-005603-kjcbbgse	210	35	study	study	NN
cord-005603-kjcbbgse	210	36	by	by	IN
cord-005603-kjcbbgse	210	37	Pittet	Pittet	NNP
cord-005603-kjcbbgse	210	38	et	et	NNP
cord-005603-kjcbbgse	210	39	al	al	NNP
cord-005603-kjcbbgse	210	40	.	.	.
cord-005603-kjcbbgse	211	1	[	[	-LRB-
cord-005603-kjcbbgse	211	2	17	17	CD
cord-005603-kjcbbgse	211	3	]	]	-RRB-
cord-005603-kjcbbgse	211	4	.	.	.
cord-005603-kjcbbgse	212	1	However	however	RB
cord-005603-kjcbbgse	212	2	,	,	,
cord-005603-kjcbbgse	212	3	16	16	CD
cord-005603-kjcbbgse	212	4	%	%	NN
cord-005603-kjcbbgse	212	5	of	of	IN
cord-005603-kjcbbgse	212	6	patients	patient	NNS
cord-005603-kjcbbgse	212	7	remained	remain	VBD
cord-005603-kjcbbgse	212	8	in	in	IN
cord-005603-kjcbbgse	212	9	the	the	DT
cord-005603-kjcbbgse	212	10	hospital	hospital	NN
cord-005603-kjcbbgse	212	11	for	for	IN
cord-005603-kjcbbgse	212	12	more	more	JJR
cord-005603-kjcbbgse	212	13	than	than	IN
cord-005603-kjcbbgse	212	14	30	30	CD
cord-005603-kjcbbgse	212	15	days	day	NNS
cord-005603-kjcbbgse	212	16	in	in	IN
cord-005603-kjcbbgse	212	17	the	the	DT
cord-005603-kjcbbgse	212	18	former	former	JJ
cord-005603-kjcbbgse	212	19	study	study	NN
cord-005603-kjcbbgse	212	20	,	,	,
cord-005603-kjcbbgse	212	21	and	and	CC
cord-005603-kjcbbgse	212	22	the	the	DT
cord-005603-kjcbbgse	212	23	median	median	JJ
cord-005603-kjcbbgse	212	24	hospital	hospital	NN
cord-005603-kjcbbgse	212	25	stay	stay	NN
cord-005603-kjcbbgse	212	26	of	of	IN
cord-005603-kjcbbgse	212	27	survivors	survivor	NNS
cord-005603-kjcbbgse	212	28	was	be	VBD
cord-005603-kjcbbgse	212	29	34	34	CD
cord-005603-kjcbbgse	212	30	days	day	NNS
cord-005603-kjcbbgse	212	31	,	,	,
cord-005603-kjcbbgse	212	32	with	with	IN
cord-005603-kjcbbgse	212	33	lengths	length	NNS
cord-005603-kjcbbgse	212	34	of	of	IN
cord-005603-kjcbbgse	212	35	stay	stay	NN
cord-005603-kjcbbgse	212	36	ranging	range	VBG
cord-005603-kjcbbgse	212	37	from	from	IN
cord-005603-kjcbbgse	212	38	1	1	CD
cord-005603-kjcbbgse	212	39	to	to	IN
cord-005603-kjcbbgse	212	40	87	87	CD
cord-005603-kjcbbgse	212	41	days	day	NNS
cord-005603-kjcbbgse	212	42	[	[	-LRB-
cord-005603-kjcbbgse	212	43	13	13	CD
cord-005603-kjcbbgse	212	44	]	]	-RRB-
cord-005603-kjcbbgse	212	45	.	.	.
cord-005603-kjcbbgse	213	1	These	these	DT
cord-005603-kjcbbgse	213	2	data	datum	NNS
cord-005603-kjcbbgse	213	3	suggest	suggest	VBP
cord-005603-kjcbbgse	213	4	that	that	IN
cord-005603-kjcbbgse	213	5	it	-PRON-	PRP
cord-005603-kjcbbgse	213	6	would	would	MD
cord-005603-kjcbbgse	213	7	be	be	VB
cord-005603-kjcbbgse	213	8	advisable	advisable	JJ
cord-005603-kjcbbgse	213	9	to	to	TO
cord-005603-kjcbbgse	213	10	assess	assess	VB
cord-005603-kjcbbgse	213	11	the	the	DT
cord-005603-kjcbbgse	213	12	outcome	outcome	NN
cord-005603-kjcbbgse	213	13	of	of	IN
cord-005603-kjcbbgse	213	14	sepsis	sepsis	NN
cord-005603-kjcbbgse	213	15	at	at	IN
cord-005603-kjcbbgse	213	16	least	least	JJS
cord-005603-kjcbbgse	213	17	after	after	IN
cord-005603-kjcbbgse	213	18	3	3	CD
cord-005603-kjcbbgse	213	19	rather	rather	RB
cord-005603-kjcbbgse	213	20	than	than	IN
cord-005603-kjcbbgse	213	21	1	1	CD
cord-005603-kjcbbgse	213	22	months	month	NNS
cord-005603-kjcbbgse	213	23	after	after	IN
cord-005603-kjcbbgse	213	24	sepsis	sepsis	NN
cord-005603-kjcbbgse	213	25	.	.	.
cord-005603-kjcbbgse	214	1	Similarly	similarly	RB
cord-005603-kjcbbgse	214	2	,	,	,
cord-005603-kjcbbgse	214	3	Sands	Sands	NNPS
cord-005603-kjcbbgse	214	4	et	et	NNP
cord-005603-kjcbbgse	214	5	al	al	NNP
cord-005603-kjcbbgse	214	6	.	.	NNP
cord-005603-kjcbbgse	214	7	reported	report	VBD
cord-005603-kjcbbgse	214	8	that	that	IN
cord-005603-kjcbbgse	214	9	the	the	DT
cord-005603-kjcbbgse	214	10	crude	crude	JJ
cord-005603-kjcbbgse	214	11	mortality	mortality	NN
cord-005603-kjcbbgse	214	12	of	of	IN
cord-005603-kjcbbgse	214	13	patients	patient	NNS
cord-005603-kjcbbgse	214	14	with	with	IN
cord-005603-kjcbbgse	214	15	severe	severe	JJ
cord-005603-kjcbbgse	214	16	sepsis	sepsis	NN
cord-005603-kjcbbgse	214	17	was	be	VBD
cord-005603-kjcbbgse	214	18	34	34	CD
cord-005603-kjcbbgse	214	19	%	%	NN
cord-005603-kjcbbgse	214	20	at	at	IN
cord-005603-kjcbbgse	214	21	28	28	CD
cord-005603-kjcbbgse	214	22	days	day	NNS
cord-005603-kjcbbgse	214	23	and	and	CC
cord-005603-kjcbbgse	214	24	45	45	CD
cord-005603-kjcbbgse	214	25	%	%	NN
cord-005603-kjcbbgse	214	26	at	at	IN
cord-005603-kjcbbgse	214	27	five	five	CD
cord-005603-kjcbbgse	214	28	months	month	NNS
cord-005603-kjcbbgse	214	29	post	post	JJ
cord-005603-kjcbbgse	214	30	-	-	JJ
cord-005603-kjcbbgse	214	31	discharge	discharge	JJ
cord-005603-kjcbbgse	214	32	[	[	-LRB-
cord-005603-kjcbbgse	214	33	8	8	CD
cord-005603-kjcbbgse	214	34	]	]	-RRB-
cord-005603-kjcbbgse	214	35	.	.	.
cord-005603-kjcbbgse	215	1	Sasse	Sasse	NNP
cord-005603-kjcbbgse	215	2	et	et	FW
cord-005603-kjcbbgse	215	3	al	al	NNP
cord-005603-kjcbbgse	215	4	.	.	.
cord-005603-kjcbbgse	216	1	[	[	-LRB-
cord-005603-kjcbbgse	216	2	30	30	CD
cord-005603-kjcbbgse	216	3	]	]	-RRB-
cord-005603-kjcbbgse	216	4	reported	report	VBD
cord-005603-kjcbbgse	216	5	a	a	DT
cord-005603-kjcbbgse	216	6	crude	crude	JJ
cord-005603-kjcbbgse	216	7	28-day	28-day	CD
cord-005603-kjcbbgse	216	8	and	and	CC
cord-005603-kjcbbgse	216	9	hospital	hospital	NN
cord-005603-kjcbbgse	216	10	mortality	mortality	NN
cord-005603-kjcbbgse	216	11	rate	rate	NN
cord-005603-kjcbbgse	216	12	of	of	IN
cord-005603-kjcbbgse	216	13	40	40	CD
cord-005603-kjcbbgse	216	14	%	%	NN
cord-005603-kjcbbgse	216	15	and	and	CC
cord-005603-kjcbbgse	216	16	51	51	CD
cord-005603-kjcbbgse	216	17	%	%	NN
cord-005603-kjcbbgse	216	18	,	,	,
cord-005603-kjcbbgse	216	19	respectively	respectively	RB
cord-005603-kjcbbgse	216	20	,	,	,
cord-005603-kjcbbgse	216	21	in	in	IN
cord-005603-kjcbbgse	216	22	153	153	CD
cord-005603-kjcbbgse	216	23	ICU	ICU	NNP
cord-005603-kjcbbgse	216	24	patients	patient	NNS
cord-005603-kjcbbgse	216	25	with	with	IN
cord-005603-kjcbbgse	216	26	bacteraemic	bacteraemic	NNP
cord-005603-kjcbbgse	216	27	sepsis	sepsis	NN
cord-005603-kjcbbgse	216	28	,	,	,
cord-005603-kjcbbgse	216	29	and	and	CC
cord-005603-kjcbbgse	216	30	of	of	IN
cord-005603-kjcbbgse	216	31	65	65	CD
cord-005603-kjcbbgse	216	32	%	%	NN
cord-005603-kjcbbgse	216	33	and	and	CC
cord-005603-kjcbbgse	216	34	72	72	CD
cord-005603-kjcbbgse	216	35	%	%	NN
cord-005603-kjcbbgse	216	36	respectively	respectively	RB
cord-005603-kjcbbgse	216	37	at	at	IN
cord-005603-kjcbbgse	216	38	6	6	CD
cord-005603-kjcbbgse	216	39	months	month	NNS
cord-005603-kjcbbgse	216	40	and	and	CC
cord-005603-kjcbbgse	216	41	1	1	CD
cord-005603-kjcbbgse	216	42	year	year	NN
cord-005603-kjcbbgse	216	43	after	after	IN
cord-005603-kjcbbgse	216	44	admission	admission	NN
cord-005603-kjcbbgse	216	45	;	;	:
cord-005603-kjcbbgse	216	46	it	-PRON-	PRP
cord-005603-kjcbbgse	216	47	should	should	MD
cord-005603-kjcbbgse	216	48	be	be	VB
cord-005603-kjcbbgse	216	49	emphasised	emphasise	VBN
cord-005603-kjcbbgse	216	50	that	that	IN
cord-005603-kjcbbgse	216	51	in	in	IN
cord-005603-kjcbbgse	216	52	this	this	DT
cord-005603-kjcbbgse	216	53	particular	particular	JJ
cord-005603-kjcbbgse	216	54	study	study	NN
cord-005603-kjcbbgse	216	55	,	,	,
cord-005603-kjcbbgse	216	56	25	25	CD
cord-005603-kjcbbgse	216	57	%	%	NN
cord-005603-kjcbbgse	216	58	of	of	IN
cord-005603-kjcbbgse	216	59	patients	patient	NNS
cord-005603-kjcbbgse	216	60	each	each	DT
cord-005603-kjcbbgse	216	61	had	have	VBD
cord-005603-kjcbbgse	216	62	HIV	HIV	NNP
cord-005603-kjcbbgse	216	63	infection	infection	NN
cord-005603-kjcbbgse	216	64	or	or	CC
cord-005603-kjcbbgse	216	65	malignancy	malignancy	NN
cord-005603-kjcbbgse	216	66	.	.	.
cord-005603-kjcbbgse	217	1	Finally	finally	RB
cord-005603-kjcbbgse	217	2	,	,	,
cord-005603-kjcbbgse	217	3	Rangel	Rangel	NNP
cord-005603-kjcbbgse	217	4	-	-	HYPH
cord-005603-kjcbbgse	217	5	Frausto	Frausto	NNP
cord-005603-kjcbbgse	217	6	et	et	NNP
cord-005603-kjcbbgse	217	7	al	al	NNP
cord-005603-kjcbbgse	217	8	.	.	NNP
cord-005603-kjcbbgse	217	9	,	,	,
cord-005603-kjcbbgse	217	10	reported	report	VBD
cord-005603-kjcbbgse	217	11	a	a	DT
cord-005603-kjcbbgse	217	12	28-day	28-day	CD
cord-005603-kjcbbgse	217	13	crude	crude	JJ
cord-005603-kjcbbgse	217	14	mortality	mortality	NN
cord-005603-kjcbbgse	217	15	of	of	IN
cord-005603-kjcbbgse	217	16	9	9	CD
cord-005603-kjcbbgse	217	17	%	%	NN
cord-005603-kjcbbgse	217	18	in	in	IN
cord-005603-kjcbbgse	217	19	the	the	DT
cord-005603-kjcbbgse	217	20	cohort	cohort	NN
cord-005603-kjcbbgse	217	21	of	of	IN
cord-005603-kjcbbgse	217	22	2527	2527	CD
cord-005603-kjcbbgse	217	23	patients	patient	NNS
cord-005603-kjcbbgse	217	24	meeting	meet	VBG
cord-005603-kjcbbgse	217	25	at	at	IN
cord-005603-kjcbbgse	217	26	least	least	JJS
cord-005603-kjcbbgse	217	27	SIRS	SIRS	NNP
cord-005603-kjcbbgse	217	28	criteria	criterion	NNS
cord-005603-kjcbbgse	217	29	;	;	:
cord-005603-kjcbbgse	217	30	an	an	DT
cord-005603-kjcbbgse	217	31	additional	additional	JJ
cord-005603-kjcbbgse	217	32	111	111	CD
cord-005603-kjcbbgse	217	33	patients	patient	NNS
cord-005603-kjcbbgse	217	34	died	die	VBD
cord-005603-kjcbbgse	217	35	during	during	IN
cord-005603-kjcbbgse	217	36	the	the	DT
cord-005603-kjcbbgse	217	37	ensuing	ensue	VBG
cord-005603-kjcbbgse	217	38	3	3	CD
cord-005603-kjcbbgse	217	39	months	month	NNS
cord-005603-kjcbbgse	217	40	,	,	,
cord-005603-kjcbbgse	217	41	and	and	CC
cord-005603-kjcbbgse	217	42	113	113	CD
cord-005603-kjcbbgse	217	43	more	more	JJR
cord-005603-kjcbbgse	217	44	between	between	IN
cord-005603-kjcbbgse	217	45	3	3	CD
cord-005603-kjcbbgse	217	46	and	and	CC
cord-005603-kjcbbgse	217	47	6	6	CD
cord-005603-kjcbbgse	217	48	months	month	NNS
cord-005603-kjcbbgse	217	49	follow	follow	NN
cord-005603-kjcbbgse	217	50	-	-	HYPH
cord-005603-kjcbbgse	217	51	up	up	NN
cord-005603-kjcbbgse	217	52	[	[	-LRB-
cord-005603-kjcbbgse	217	53	6	6	CD
cord-005603-kjcbbgse	217	54	]	]	-RRB-
cord-005603-kjcbbgse	217	55	.	.	.
cord-005603-kjcbbgse	218	1	The	the	DT
cord-005603-kjcbbgse	218	2	overall	overall	JJ
cord-005603-kjcbbgse	218	3	crude	crude	JJ
cord-005603-kjcbbgse	218	4	mortality	mortality	NN
cord-005603-kjcbbgse	218	5	rate	rate	NN
cord-005603-kjcbbgse	218	6	at	at	IN
cord-005603-kjcbbgse	218	7	6	6	CD
cord-005603-kjcbbgse	218	8	months	month	NNS
cord-005603-kjcbbgse	218	9	was	be	VBD
cord-005603-kjcbbgse	218	10	therefore	therefore	RB
cord-005603-kjcbbgse	218	11	of	of	IN
cord-005603-kjcbbgse	218	12	17	17	CD
cord-005603-kjcbbgse	218	13	%	%	NN
cord-005603-kjcbbgse	218	14	in	in	IN
cord-005603-kjcbbgse	218	15	patients	patient	NNS
cord-005603-kjcbbgse	218	16	meeting	meet	VBG
cord-005603-kjcbbgse	218	17	at	at	IN
cord-005603-kjcbbgse	218	18	least	least	JJS
cord-005603-kjcbbgse	218	19	SIRS	SIRS	NNP
cord-005603-kjcbbgse	218	20	criteria	criterion	NNS
cord-005603-kjcbbgse	218	21	.	.	.
cord-005603-kjcbbgse	219	1	However	however	RB
cord-005603-kjcbbgse	219	2	,	,	,
cord-005603-kjcbbgse	219	3	the	the	DT
cord-005603-kjcbbgse	219	4	relative	relative	JJ
cord-005603-kjcbbgse	219	5	part	part	NN
cord-005603-kjcbbgse	219	6	of	of	IN
cord-005603-kjcbbgse	219	7	sepsis	sepsis	NN
cord-005603-kjcbbgse	219	8	and	and	CC
cord-005603-kjcbbgse	219	9	other	other	JJ
cord-005603-kjcbbgse	219	10	host	host	NN
cord-005603-kjcbbgse	219	11	factors	factor	NNS
cord-005603-kjcbbgse	219	12	in	in	IN
cord-005603-kjcbbgse	219	13	the	the	DT
cord-005603-kjcbbgse	219	14	overall	overall	JJ
cord-005603-kjcbbgse	219	15	mortality	mortality	NN
cord-005603-kjcbbgse	219	16	is	be	VBZ
cord-005603-kjcbbgse	219	17	unknown	unknown	JJ
cord-005603-kjcbbgse	219	18	.	.	.
cord-005603-kjcbbgse	220	1	Perl	Perl	NNP
cord-005603-kjcbbgse	220	2	et	et	NNP
cord-005603-kjcbbgse	220	3	al	al	NNP
cord-005603-kjcbbgse	220	4	.	.	NNP
cord-005603-kjcbbgse	220	5	,	,	,
cord-005603-kjcbbgse	220	6	have	have	VBP
cord-005603-kjcbbgse	220	7	addressed	address	VBN
cord-005603-kjcbbgse	220	8	part	part	NN
cord-005603-kjcbbgse	220	9	of	of	IN
cord-005603-kjcbbgse	220	10	the	the	DT
cord-005603-kjcbbgse	220	11	problem	problem	NN
cord-005603-kjcbbgse	220	12	by	by	IN
cord-005603-kjcbbgse	220	13	examining	examine	VBG
cord-005603-kjcbbgse	220	14	factors	factor	NNS
cord-005603-kjcbbgse	220	15	associated	associate	VBN
cord-005603-kjcbbgse	220	16	with	with	IN
cord-005603-kjcbbgse	220	17	late	late	JJ
cord-005603-kjcbbgse	220	18	mortality	mortality	NN
cord-005603-kjcbbgse	220	19	after	after	IN
cord-005603-kjcbbgse	220	20	sepsis	sepsis	NN
cord-005603-kjcbbgse	220	21	in	in	IN
cord-005603-kjcbbgse	220	22	a	a	DT
cord-005603-kjcbbgse	220	23	cohort	cohort	NN
cord-005603-kjcbbgse	220	24	of	of	IN
cord-005603-kjcbbgse	220	25	100	100	CD
cord-005603-kjcbbgse	220	26	patients	patient	NNS
cord-005603-kjcbbgse	220	27	with	with	IN
cord-005603-kjcbbgse	220	28	severe	severe	JJ
cord-005603-kjcbbgse	220	29	sepsis	sepsis	NN
cord-005603-kjcbbgse	220	30	entered	enter	VBN
cord-005603-kjcbbgse	220	31	in	in	IN
cord-005603-kjcbbgse	220	32	one	one	CD
cord-005603-kjcbbgse	220	33	clinical	clinical	JJ
cord-005603-kjcbbgse	220	34	trial	trial	NN
cord-005603-kjcbbgse	220	35	of	of	IN
cord-005603-kjcbbgse	220	36	anti	anti	JJ
cord-005603-kjcbbgse	220	37	-	-	JJ
cord-005603-kjcbbgse	220	38	endotoxin	endotoxin	JJ
cord-005603-kjcbbgse	220	39	antibodies	antibody	NNS
cord-005603-kjcbbgse	220	40	[	[	-LRB-
cord-005603-kjcbbgse	220	41	20	20	CD
cord-005603-kjcbbgse	220	42	]	]	-RRB-
cord-005603-kjcbbgse	220	43	.	.	.
cord-005603-kjcbbgse	221	1	In	in	IN
cord-005603-kjcbbgse	221	2	that	that	DT
cord-005603-kjcbbgse	221	3	study	study	NN
cord-005603-kjcbbgse	221	4	,	,	,
cord-005603-kjcbbgse	221	5	the	the	DT
cord-005603-kjcbbgse	221	6	crude	crude	JJ
cord-005603-kjcbbgse	221	7	mortality	mortality	NN
cord-005603-kjcbbgse	221	8	of	of	IN
cord-005603-kjcbbgse	221	9	patients	patient	NNS
cord-005603-kjcbbgse	221	10	was	be	VBD
cord-005603-kjcbbgse	221	11	32	32	CD
cord-005603-kjcbbgse	221	12	%	%	NN
cord-005603-kjcbbgse	221	13	at	at	IN
cord-005603-kjcbbgse	221	14	1	1	CD
cord-005603-kjcbbgse	221	15	month	month	NN
cord-005603-kjcbbgse	221	16	,	,	,
cord-005603-kjcbbgse	221	17	37	37	CD
cord-005603-kjcbbgse	221	18	%	%	NN
cord-005603-kjcbbgse	221	19	at	at	IN
cord-005603-kjcbbgse	221	20	3	3	CD
cord-005603-kjcbbgse	221	21	months	month	NNS
cord-005603-kjcbbgse	221	22	,	,	,
cord-005603-kjcbbgse	221	23	and	and	CC
cord-005603-kjcbbgse	221	24	43	43	CD
cord-005603-kjcbbgse	221	25	%	%	NN
cord-005603-kjcbbgse	221	26	at	at	IN
cord-005603-kjcbbgse	221	27	6	6	CD
cord-005603-kjcbbgse	221	28	months	month	NNS
cord-005603-kjcbbgse	221	29	;	;	:
cord-005603-kjcbbgse	221	30	after	after	IN
cord-005603-kjcbbgse	221	31	a	a	DT
cord-005603-kjcbbgse	221	32	mean	mean	JJ
cord-005603-kjcbbgse	221	33	follow	follow	NN
cord-005603-kjcbbgse	221	34	-	-	HYPH
cord-005603-kjcbbgse	221	35	up	up	NN
cord-005603-kjcbbgse	221	36	of	of	IN
cord-005603-kjcbbgse	221	37	30	30	CD
cord-005603-kjcbbgse	221	38	months	month	NNS
cord-005603-kjcbbgse	221	39	,	,	,
cord-005603-kjcbbgse	221	40	60	60	CD
cord-005603-kjcbbgse	221	41	%	%	NN
cord-005603-kjcbbgse	221	42	patients	patient	NNS
cord-005603-kjcbbgse	221	43	had	have	VBD
cord-005603-kjcbbgse	221	44	died	die	VBN
cord-005603-kjcbbgse	221	45	.	.	.
cord-005603-kjcbbgse	222	1	When	when	WRB
cord-005603-kjcbbgse	222	2	examining	examine	VBG
cord-005603-kjcbbgse	222	3	factors	factor	NNS
cord-005603-kjcbbgse	222	4	associated	associate	VBN
cord-005603-kjcbbgse	222	5	with	with	IN
cord-005603-kjcbbgse	222	6	mortality	mortality	NN
cord-005603-kjcbbgse	222	7	at	at	IN
cord-005603-kjcbbgse	222	8	those	those	DT
cord-005603-kjcbbgse	222	9	different	different	JJ
cord-005603-kjcbbgse	222	10	points	point	NNS
cord-005603-kjcbbgse	222	11	in	in	IN
cord-005603-kjcbbgse	222	12	time	time	NN
cord-005603-kjcbbgse	222	13	after	after	IN
cord-005603-kjcbbgse	222	14	sepsis	sepsis	NN
cord-005603-kjcbbgse	222	15	,	,	,
cord-005603-kjcbbgse	222	16	they	-PRON-	PRP
cord-005603-kjcbbgse	222	17	found	find	VBD
cord-005603-kjcbbgse	222	18	that	that	IN
cord-005603-kjcbbgse	222	19	all	all	DT
cord-005603-kjcbbgse	222	20	models	model	NNS
cord-005603-kjcbbgse	222	21	included	include	VBD
cord-005603-kjcbbgse	222	22	the	the	DT
cord-005603-kjcbbgse	222	23	severity	severity	NN
cord-005603-kjcbbgse	222	24	of	of	IN
cord-005603-kjcbbgse	222	25	underlying	underlie	VBG
cord-005603-kjcbbgse	222	26	disease	disease	NN
cord-005603-kjcbbgse	222	27	(	(	-LRB-
cord-005603-kjcbbgse	222	28	MacCabe	maccabe	CD
cord-005603-kjcbbgse	222	29	classification	classification	NN
cord-005603-kjcbbgse	222	30	)	)	-RRB-
cord-005603-kjcbbgse	222	31	and	and	CC
cord-005603-kjcbbgse	222	32	a	a	DT
cord-005603-kjcbbgse	222	33	combined	combined	JJ
cord-005603-kjcbbgse	222	34	index	index	NN
cord-005603-kjcbbgse	222	35	of	of	IN
cord-005603-kjcbbgse	222	36	comorbidities	comorbiditie	NNS
cord-005603-kjcbbgse	222	37	,	,	,
cord-005603-kjcbbgse	222	38	in	in	IN
cord-005603-kjcbbgse	222	39	addition	addition	NN
cord-005603-kjcbbgse	222	40	to	to	IN
cord-005603-kjcbbgse	222	41	vasopressors	vasopressor	NNS
cord-005603-kjcbbgse	222	42	(	(	-LRB-
cord-005603-kjcbbgse	222	43	or	or	CC
cord-005603-kjcbbgse	222	44	shock	shock	NN
cord-005603-kjcbbgse	222	45	)	)	-RRB-
cord-005603-kjcbbgse	222	46	and	and	CC
cord-005603-kjcbbgse	222	47	ventilator	ventilator	NN
cord-005603-kjcbbgse	222	48	use	use	NN
cord-005603-kjcbbgse	222	49	(	(	-LRB-
cord-005603-kjcbbgse	222	50	or	or	CC
cord-005603-kjcbbgse	222	51	ARDS	ARDS	NNP
cord-005603-kjcbbgse	222	52	)	)	-RRB-
cord-005603-kjcbbgse	222	53	.	.	.
cord-005603-kjcbbgse	223	1	Therefore	therefore	RB
cord-005603-kjcbbgse	223	2	,	,	,
cord-005603-kjcbbgse	223	3	pre	pre	JJ
cord-005603-kjcbbgse	223	4	-	-	JJ
cord-005603-kjcbbgse	223	5	existing	existing	JJ
cord-005603-kjcbbgse	223	6	illness	illness	NN
cord-005603-kjcbbgse	223	7	and	and	CC
cord-005603-kjcbbgse	223	8	comorbidities	comorbiditie	NNS
cord-005603-kjcbbgse	223	9	,	,	,
cord-005603-kjcbbgse	223	10	in	in	IN
cord-005603-kjcbbgse	223	11	addition	addition	NN
cord-005603-kjcbbgse	223	12	to	to	TO
cord-005603-kjcbbgse	223	13	shock	shock	NN
cord-005603-kjcbbgse	223	14	and	and	CC
cord-005603-kjcbbgse	223	15	organ	organ	NN
cord-005603-kjcbbgse	223	16	failures	failure	NNS
cord-005603-kjcbbgse	223	17	(	(	-LRB-
cord-005603-kjcbbgse	223	18	i.	i.	NNP
cord-005603-kjcbbgse	223	19	e.	e.	NNP
cord-005603-kjcbbgse	223	20	,	,	,
cord-005603-kjcbbgse	223	21	ARDS	ARDS	NNP
cord-005603-kjcbbgse	223	22	)	)	-RRB-
cord-005603-kjcbbgse	223	23	,	,	,
cord-005603-kjcbbgse	223	24	are	be	VBP
cord-005603-kjcbbgse	223	25	also	also	RB
cord-005603-kjcbbgse	223	26	confirmed	confirm	VBN
cord-005603-kjcbbgse	223	27	as	as	IN
cord-005603-kjcbbgse	223	28	important	important	JJ
cord-005603-kjcbbgse	223	29	predictors	predictor	NNS
cord-005603-kjcbbgse	223	30	of	of	IN
cord-005603-kjcbbgse	223	31	long	long	JJ
cord-005603-kjcbbgse	223	32	-	-	HYPH
cord-005603-kjcbbgse	223	33	term	term	NN
cord-005603-kjcbbgse	223	34	outcome	outcome	NN
cord-005603-kjcbbgse	223	35	in	in	IN
cord-005603-kjcbbgse	223	36	this	this	DT
cord-005603-kjcbbgse	223	37	study	study	NN
cord-005603-kjcbbgse	223	38	.	.	.
cord-005603-kjcbbgse	224	1	An	an	DT
cord-005603-kjcbbgse	224	2	elegant	elegant	JJ
cord-005603-kjcbbgse	224	3	study	study	NN
cord-005603-kjcbbgse	224	4	by	by	IN
cord-005603-kjcbbgse	224	5	Quartin	Quartin	NNP
cord-005603-kjcbbgse	224	6	et	et	FW
cord-005603-kjcbbgse	224	7	al	al	NNP
cord-005603-kjcbbgse	224	8	.	.	.
cord-005603-kjcbbgse	225	1	[	[	-LRB-
cord-005603-kjcbbgse	225	2	16	16	CD
cord-005603-kjcbbgse	225	3	]	]	-RRB-
cord-005603-kjcbbgse	225	4	has	have	VBZ
cord-005603-kjcbbgse	225	5	provided	provide	VBN
cord-005603-kjcbbgse	225	6	some	some	DT
cord-005603-kjcbbgse	225	7	more	more	JJR
cord-005603-kjcbbgse	225	8	insight	insight	NN
cord-005603-kjcbbgse	225	9	into	into	IN
cord-005603-kjcbbgse	225	10	the	the	DT
cord-005603-kjcbbgse	225	11	problem	problem	NN
cord-005603-kjcbbgse	225	12	of	of	IN
cord-005603-kjcbbgse	225	13	long	long	JJ
cord-005603-kjcbbgse	225	14	-	-	HYPH
cord-005603-kjcbbgse	225	15	term	term	NN
cord-005603-kjcbbgse	225	16	mortality	mortality	NN
cord-005603-kjcbbgse	225	17	attributable	attributable	JJ
cord-005603-kjcbbgse	225	18	to	to	IN
cord-005603-kjcbbgse	225	19	sepsis	sepsis	NN
cord-005603-kjcbbgse	225	20	.	.	.
cord-005603-kjcbbgse	226	1	These	these	DT
cord-005603-kjcbbgse	226	2	authors	author	NNS
cord-005603-kjcbbgse	226	3	have	have	VBP
cord-005603-kjcbbgse	226	4	estimated	estimate	VBN
cord-005603-kjcbbgse	226	5	the	the	DT
cord-005603-kjcbbgse	226	6	increased	increase	VBN
cord-005603-kjcbbgse	226	7	risk	risk	NN
cord-005603-kjcbbgse	226	8	of	of	IN
cord-005603-kjcbbgse	226	9	mortality	mortality	NN
cord-005603-kjcbbgse	226	10	attributable	attributable	JJ
cord-005603-kjcbbgse	226	11	to	to	IN
cord-005603-kjcbbgse	226	12	sepsis	sepsis	NN
cord-005603-kjcbbgse	226	13	over	over	IN
cord-005603-kjcbbgse	226	14	a	a	DT
cord-005603-kjcbbgse	226	15	6-year	6-year	JJ
cord-005603-kjcbbgse	226	16	follow	follow	NN
cord-005603-kjcbbgse	226	17	-	-	HYPH
cord-005603-kjcbbgse	226	18	up	up	NN
cord-005603-kjcbbgse	226	19	period	period	NN
cord-005603-kjcbbgse	226	20	in	in	IN
cord-005603-kjcbbgse	226	21	patients	patient	NNS
cord-005603-kjcbbgse	226	22	qualifying	qualify	VBG
cord-005603-kjcbbgse	226	23	for	for	IN
cord-005603-kjcbbgse	226	24	sepsis	sepsis	NN
cord-005603-kjcbbgse	226	25	and	and	CC
cord-005603-kjcbbgse	226	26	entered	enter	VBD
cord-005603-kjcbbgse	226	27	into	into	IN
cord-005603-kjcbbgse	226	28	a	a	DT
cord-005603-kjcbbgse	226	29	clinical	clinical	JJ
cord-005603-kjcbbgse	226	30	trial	trial	NN
cord-005603-kjcbbgse	226	31	of	of	IN
cord-005603-kjcbbgse	226	32	corticosteroid	corticosteroid	NN
cord-005603-kjcbbgse	226	33	therapy	therapy	NN
cord-005603-kjcbbgse	226	34	,	,	,
cord-005603-kjcbbgse	226	35	as	as	IN
cord-005603-kjcbbgse	226	36	compared	compare	VBN
cord-005603-kjcbbgse	226	37	to	to	IN
cord-005603-kjcbbgse	226	38	a	a	DT
cord-005603-kjcbbgse	226	39	control	control	NN
cord-005603-kjcbbgse	226	40	cohort	cohort	NN
cord-005603-kjcbbgse	226	41	of	of	IN
cord-005603-kjcbbgse	226	42	non	non	JJ
cord-005603-kjcbbgse	226	43	-	-	JJ
cord-005603-kjcbbgse	226	44	septic	septic	JJ
cord-005603-kjcbbgse	226	45	hospitalised	hospitalise	VBN
cord-005603-kjcbbgse	226	46	patients	patient	NNS
cord-005603-kjcbbgse	226	47	,	,	,
cord-005603-kjcbbgse	226	48	after	after	IN
cord-005603-kjcbbgse	226	49	adjustment	adjustment	NN
cord-005603-kjcbbgse	226	50	on	on	IN
cord-005603-kjcbbgse	226	51	risk	risk	NN
cord-005603-kjcbbgse	226	52	factors	factor	NNS
cord-005603-kjcbbgse	226	53	for	for	IN
cord-005603-kjcbbgse	226	54	death	death	NN
cord-005603-kjcbbgse	226	55	in	in	IN
cord-005603-kjcbbgse	226	56	the	the	DT
cord-005603-kjcbbgse	226	57	control	control	NN
cord-005603-kjcbbgse	226	58	cohort	cohort	NN
cord-005603-kjcbbgse	226	59	.	.	.
cord-005603-kjcbbgse	227	1	After	after	IN
cord-005603-kjcbbgse	227	2	8	8	CD
cord-005603-kjcbbgse	227	3	years	year	NNS
cord-005603-kjcbbgse	227	4	,	,	,
cord-005603-kjcbbgse	227	5	1229	1229	CD
cord-005603-kjcbbgse	227	6	(	(	-LRB-
cord-005603-kjcbbgse	227	7	82	82	CD
cord-005603-kjcbbgse	227	8	%	%	NN
cord-005603-kjcbbgse	227	9	)	)	-RRB-
cord-005603-kjcbbgse	227	10	of	of	IN
cord-005603-kjcbbgse	227	11	the	the	DT
cord-005603-kjcbbgse	227	12	1505	1505	CD
cord-005603-kjcbbgse	227	13	septic	septic	JJ
cord-005603-kjcbbgse	227	14	patients	patient	NNS
cord-005603-kjcbbgse	227	15	had	have	VBD
cord-005603-kjcbbgse	227	16	died	die	VBN
cord-005603-kjcbbgse	227	17	.	.	.
cord-005603-kjcbbgse	228	1	The	the	DT
cord-005603-kjcbbgse	228	2	authors	author	NNS
cord-005603-kjcbbgse	228	3	estimated	estimate	VBD
cord-005603-kjcbbgse	228	4	that	that	IN
cord-005603-kjcbbgse	228	5	septic	septic	JJ
cord-005603-kjcbbgse	228	6	patients	patient	NNS
cord-005603-kjcbbgse	228	7	had	have	VBD
cord-005603-kjcbbgse	228	8	an	an	DT
cord-005603-kjcbbgse	228	9	increased	increase	VBN
cord-005603-kjcbbgse	228	10	mortality	mortality	NN
cord-005603-kjcbbgse	228	11	risk	risk	NN
cord-005603-kjcbbgse	228	12	persisting	persist	VBG
cord-005603-kjcbbgse	228	13	beyond	beyond	IN
cord-005603-kjcbbgse	228	14	one	one	CD
cord-005603-kjcbbgse	228	15	month	month	NN
cord-005603-kjcbbgse	228	16	and	and	CC
cord-005603-kjcbbgse	228	17	over	over	IN
cord-005603-kjcbbgse	228	18	the	the	DT
cord-005603-kjcbbgse	228	19	five	five	CD
cord-005603-kjcbbgse	228	20	years	year	NNS
cord-005603-kjcbbgse	228	21	following	follow	VBG
cord-005603-kjcbbgse	228	22	sepsis	sepsis	NN
cord-005603-kjcbbgse	228	23	;	;	:
cord-005603-kjcbbgse	228	24	the	the	DT
cord-005603-kjcbbgse	228	25	increased	increase	VBN
cord-005603-kjcbbgse	228	26	risk	risk	NN
cord-005603-kjcbbgse	228	27	was	be	VBD
cord-005603-kjcbbgse	228	28	apparent	apparent	JJ
cord-005603-kjcbbgse	228	29	in	in	IN
cord-005603-kjcbbgse	228	30	all	all	DT
cord-005603-kjcbbgse	228	31	stages	stage	NNS
cord-005603-kjcbbgse	228	32	of	of	IN
cord-005603-kjcbbgse	228	33	septic	septic	JJ
cord-005603-kjcbbgse	228	34	syndromes	syndrome	NNS
cord-005603-kjcbbgse	228	35	.	.	.
cord-005603-kjcbbgse	229	1	The	the	DT
cord-005603-kjcbbgse	229	2	median	median	NN
cord-005603-kjcbbgse	229	3	predicted	predict	VBD
cord-005603-kjcbbgse	229	4	life	life	NN
cord-005603-kjcbbgse	229	5	expectancy	expectancy	NN
cord-005603-kjcbbgse	229	6	was	be	VBD
cord-005603-kjcbbgse	229	7	5	5	CD
cord-005603-kjcbbgse	229	8	years	year	NNS
cord-005603-kjcbbgse	229	9	among	among	IN
cord-005603-kjcbbgse	229	10	septic	septic	JJ
cord-005603-kjcbbgse	229	11	patients	patient	NNS
cord-005603-kjcbbgse	229	12	.	.	.
cord-005603-kjcbbgse	230	1	The	the	DT
cord-005603-kjcbbgse	230	2	average	average	JJ
cord-005603-kjcbbgse	230	3	life	life	NN
cord-005603-kjcbbgse	230	4	expectancy	expectancy	NN
cord-005603-kjcbbgse	230	5	cost	cost	NN
cord-005603-kjcbbgse	230	6	of	of	IN
cord-005603-kjcbbgse	230	7	sepsis	sepsis	NN
cord-005603-kjcbbgse	230	8	was	be	VBD
cord-005603-kjcbbgse	230	9	estimated	estimate	VBN
cord-005603-kjcbbgse	230	10	at	at	IN
cord-005603-kjcbbgse	230	11	2.4	2.4	CD
cord-005603-kjcbbgse	230	12	years	year	NNS
cord-005603-kjcbbgse	230	13	and	and	CC
cord-005603-kjcbbgse	230	14	the	the	DT
cord-005603-kjcbbgse	230	15	median	median	JJ
cord-005603-kjcbbgse	230	16	survival	survival	NN
cord-005603-kjcbbgse	230	17	among	among	IN
cord-005603-kjcbbgse	230	18	30-day	30-day	CD
cord-005603-kjcbbgse	230	19	survivors	survivor	NNS
cord-005603-kjcbbgse	230	20	was	be	VBD
cord-005603-kjcbbgse	230	21	reduced	reduce	VBN
cord-005603-kjcbbgse	230	22	from	from	IN
cord-005603-kjcbbgse	230	23	6.2	6.2	CD
cord-005603-kjcbbgse	230	24	to	to	TO
cord-005603-kjcbbgse	230	25	2.3	2.3	CD
cord-005603-kjcbbgse	230	26	years	year	NNS
cord-005603-kjcbbgse	230	27	.	.	.
cord-005603-kjcbbgse	231	1	In	in	IN
cord-005603-kjcbbgse	231	2	the	the	DT
cord-005603-kjcbbgse	231	3	septic	septic	JJ
cord-005603-kjcbbgse	231	4	population	population	NN
cord-005603-kjcbbgse	231	5	,	,	,
cord-005603-kjcbbgse	231	6	there	there	EX
cord-005603-kjcbbgse	231	7	were	be	VBD
cord-005603-kjcbbgse	231	8	452	452	CD
cord-005603-kjcbbgse	231	9	(	(	-LRB-
cord-005603-kjcbbgse	231	10	30	30	CD
cord-005603-kjcbbgse	231	11	%	%	NN
cord-005603-kjcbbgse	231	12	)	)	-RRB-
cord-005603-kjcbbgse	231	13	more	more	JJR
cord-005603-kjcbbgse	231	14	deaths	death	NNS
cord-005603-kjcbbgse	231	15	than	than	IN
cord-005603-kjcbbgse	231	16	predicted	predict	VBN
cord-005603-kjcbbgse	231	17	from	from	IN
cord-005603-kjcbbgse	231	18	controls	control	NNS
cord-005603-kjcbbgse	231	19	within	within	IN
cord-005603-kjcbbgse	231	20	the	the	DT
cord-005603-kjcbbgse	231	21	first	first	JJ
cord-005603-kjcbbgse	231	22	month	month	NN
cord-005603-kjcbbgse	231	23	,	,	,
cord-005603-kjcbbgse	231	24	192	192	CD
cord-005603-kjcbbgse	231	25	(	(	-LRB-
cord-005603-kjcbbgse	231	26	13	13	CD
cord-005603-kjcbbgse	231	27	%	%	NN
cord-005603-kjcbbgse	231	28	)	)	-RRB-
cord-005603-kjcbbgse	231	29	more	more	JJR
cord-005603-kjcbbgse	231	30	within	within	IN
cord-005603-kjcbbgse	231	31	one	one	CD
cord-005603-kjcbbgse	231	32	year	year	NN
cord-005603-kjcbbgse	231	33	,	,	,
cord-005603-kjcbbgse	231	34	and	and	CC
cord-005603-kjcbbgse	231	35	61	61	CD
cord-005603-kjcbbgse	231	36	(	(	-LRB-
cord-005603-kjcbbgse	231	37	4	4	CD
cord-005603-kjcbbgse	231	38	%	%	NN
cord-005603-kjcbbgse	231	39	)	)	-RRB-
cord-005603-kjcbbgse	231	40	more	more	JJR
cord-005603-kjcbbgse	231	41	within	within	IN
cord-005603-kjcbbgse	231	42	5	5	CD
cord-005603-kjcbbgse	231	43	years	year	NNS
cord-005603-kjcbbgse	231	44	;	;	:
cord-005603-kjcbbgse	231	45	thus	thus	RB
cord-005603-kjcbbgse	231	46	,	,	,
cord-005603-kjcbbgse	231	47	the	the	DT
cord-005603-kjcbbgse	231	48	overall	overall	JJ
cord-005603-kjcbbgse	231	49	mortality	mortality	NN
cord-005603-kjcbbgse	231	50	attributable	attributable	JJ
cord-005603-kjcbbgse	231	51	to	to	IN
cord-005603-kjcbbgse	231	52	sepsis	sepsis	NN
cord-005603-kjcbbgse	231	53	was	be	VBD
cord-005603-kjcbbgse	231	54	43	43	CD
cord-005603-kjcbbgse	231	55	%	%	NN
cord-005603-kjcbbgse	231	56	at	at	IN
cord-005603-kjcbbgse	231	57	one	one	CD
cord-005603-kjcbbgse	231	58	year	year	NN
cord-005603-kjcbbgse	231	59	.	.	.
cord-005603-kjcbbgse	232	1	Sepsis	sepsis	NN
cord-005603-kjcbbgse	232	2	also	also	RB
cord-005603-kjcbbgse	232	3	appears	appear	VBZ
cord-005603-kjcbbgse	232	4	to	to	TO
cord-005603-kjcbbgse	232	5	significantly	significantly	RB
cord-005603-kjcbbgse	232	6	affect	affect	VB
cord-005603-kjcbbgse	232	7	the	the	DT
cord-005603-kjcbbgse	232	8	quality	quality	NN
cord-005603-kjcbbgse	232	9	of	of	IN
cord-005603-kjcbbgse	232	10	life	life	NN
cord-005603-kjcbbgse	232	11	of	of	IN
cord-005603-kjcbbgse	232	12	survivors	survivor	NNS
cord-005603-kjcbbgse	232	13	.	.	.
cord-005603-kjcbbgse	233	1	In	in	IN
cord-005603-kjcbbgse	233	2	the	the	DT
cord-005603-kjcbbgse	233	3	study	study	NN
cord-005603-kjcbbgse	233	4	by	by	IN
cord-005603-kjcbbgse	233	5	Perl	Perl	NNP
cord-005603-kjcbbgse	233	6	et	et	NNP
cord-005603-kjcbbgse	233	7	al	al	NNP
cord-005603-kjcbbgse	233	8	.	.	.
cord-005603-kjcbbgse	234	1	[	[	-LRB-
cord-005603-kjcbbgse	234	2	20	20	CD
cord-005603-kjcbbgse	234	3	]	]	-RRB-
cord-005603-kjcbbgse	234	4	survivors	survivor	NNS
cord-005603-kjcbbgse	234	5	had	have	VBD
cord-005603-kjcbbgse	234	6	lower	low	JJR
cord-005603-kjcbbgse	234	7	scores	score	NNS
cord-005603-kjcbbgse	234	8	than	than	IN
cord-005603-kjcbbgse	234	9	normal	normal	JJ
cord-005603-kjcbbgse	234	10	by	by	IN
cord-005603-kjcbbgse	234	11	functional	functional	JJ
cord-005603-kjcbbgse	234	12	status	status	NN
cord-005603-kjcbbgse	234	13	and	and	CC
cord-005603-kjcbbgse	234	14	general	general	JJ
cord-005603-kjcbbgse	234	15	health	health	NN
cord-005603-kjcbbgse	234	16	perception	perception	NN
cord-005603-kjcbbgse	234	17	scales	scale	NNS
cord-005603-kjcbbgse	234	18	.	.	.
cord-005603-kjcbbgse	235	1	It	-PRON-	PRP
cord-005603-kjcbbgse	235	2	is	be	VBZ
cord-005603-kjcbbgse	235	3	quite	quite	RB
cord-005603-kjcbbgse	235	4	clear	clear	JJ
cord-005603-kjcbbgse	235	5	from	from	IN
cord-005603-kjcbbgse	235	6	the	the	DT
cord-005603-kjcbbgse	235	7	above	above	JJ
cord-005603-kjcbbgse	235	8	epidemiological	epidemiological	JJ
cord-005603-kjcbbgse	235	9	information	information	NN
cord-005603-kjcbbgse	235	10	that	that	WDT
cord-005603-kjcbbgse	235	11	SIRS	SIRS	NNP
cord-005603-kjcbbgse	235	12	criteria	criterion	NNS
cord-005603-kjcbbgse	235	13	are	be	VBP
cord-005603-kjcbbgse	235	14	much	much	RB
cord-005603-kjcbbgse	235	15	too	too	RB
cord-005603-kjcbbgse	235	16	non	non	JJ
cord-005603-kjcbbgse	235	17	-	-	JJ
cord-005603-kjcbbgse	235	18	specific	specific	JJ
cord-005603-kjcbbgse	235	19	to	to	TO
cord-005603-kjcbbgse	235	20	be	be	VB
cord-005603-kjcbbgse	235	21	used	use	VBN
cord-005603-kjcbbgse	235	22	for	for	IN
cord-005603-kjcbbgse	235	23	the	the	DT
cord-005603-kjcbbgse	235	24	selection	selection	NN
cord-005603-kjcbbgse	235	25	of	of	IN
cord-005603-kjcbbgse	235	26	patients	patient	NNS
cord-005603-kjcbbgse	235	27	.	.	.
cord-005603-kjcbbgse	236	1	Including	include	VBG
cord-005603-kjcbbgse	236	2	patients	patient	NNS
cord-005603-kjcbbgse	236	3	characterised	characterise	VBN
cord-005603-kjcbbgse	236	4	only	only	RB
cord-005603-kjcbbgse	236	5	by	by	IN
cord-005603-kjcbbgse	236	6	these	these	DT
cord-005603-kjcbbgse	236	7	criteria	criterion	NNS
cord-005603-kjcbbgse	236	8	would	would	MD
cord-005603-kjcbbgse	236	9	only	only	RB
cord-005603-kjcbbgse	236	10	result	result	VB
cord-005603-kjcbbgse	236	11	in	in	IN
cord-005603-kjcbbgse	236	12	augmenting	augment	VBG
cord-005603-kjcbbgse	236	13	the`background	the`background	NNP
cord-005603-kjcbbgse	236	14	noise	noise	NN
cord-005603-kjcbbgse	236	15	'	'	''
cord-005603-kjcbbgse	236	16	,	,	,
cord-005603-kjcbbgse	236	17	by	by	IN
cord-005603-kjcbbgse	236	18	introducing	introduce	VBG
cord-005603-kjcbbgse	236	19	a	a	DT
cord-005603-kjcbbgse	236	20	large	large	JJ
cord-005603-kjcbbgse	236	21	population	population	NN
cord-005603-kjcbbgse	236	22	having	have	VBG
cord-005603-kjcbbgse	236	23	a	a	DT
cord-005603-kjcbbgse	236	24	<	<	XX
cord-005603-kjcbbgse	236	25	50	50	CD
cord-005603-kjcbbgse	236	26	%	%	NN
cord-005603-kjcbbgse	236	27	risk	risk	NN
cord-005603-kjcbbgse	236	28	of	of	IN
cord-005603-kjcbbgse	236	29	sepsis	sepsis	NN
cord-005603-kjcbbgse	236	30	,	,	,
cord-005603-kjcbbgse	236	31	and	and	CC
cord-005603-kjcbbgse	236	32	a	a	DT
cord-005603-kjcbbgse	236	33	low	low	JJ
cord-005603-kjcbbgse	236	34	risk	risk	NN
cord-005603-kjcbbgse	236	35	of	of	IN
cord-005603-kjcbbgse	236	36	mortality	mortality	NN
cord-005603-kjcbbgse	236	37	.	.	.
cord-005603-kjcbbgse	237	1	One	one	PRP
cord-005603-kjcbbgse	237	2	would	would	MD
cord-005603-kjcbbgse	237	3	like	like	VB
cord-005603-kjcbbgse	237	4	sepsis	sepsis	NN
cord-005603-kjcbbgse	237	5	or	or	CC
cord-005603-kjcbbgse	237	6	its	-PRON-	PRP$
cord-005603-kjcbbgse	237	7	more	more	RBR
cord-005603-kjcbbgse	237	8	severe	severe	JJ
cord-005603-kjcbbgse	237	9	forms	form	NNS
cord-005603-kjcbbgse	237	10	to	to	TO
cord-005603-kjcbbgse	237	11	be	be	VB
cord-005603-kjcbbgse	237	12	used	use	VBN
cord-005603-kjcbbgse	237	13	as	as	IN
cord-005603-kjcbbgse	237	14	criteria	criterion	NNS
cord-005603-kjcbbgse	237	15	for	for	IN
cord-005603-kjcbbgse	237	16	inclusion	inclusion	NN
cord-005603-kjcbbgse	237	17	.	.	.
cord-005603-kjcbbgse	238	1	However	however	RB
cord-005603-kjcbbgse	238	2	,	,	,
cord-005603-kjcbbgse	238	3	physicians	physician	NNS
cord-005603-kjcbbgse	238	4	remain	remain	VBP
cord-005603-kjcbbgse	238	5	with	with	IN
cord-005603-kjcbbgse	238	6	the	the	DT
cord-005603-kjcbbgse	238	7	dilemma	dilemma	NN
cord-005603-kjcbbgse	238	8	that	that	IN
cord-005603-kjcbbgse	238	9	there	there	EX
cord-005603-kjcbbgse	238	10	is	be	VBZ
cord-005603-kjcbbgse	238	11	no	no	DT
cord-005603-kjcbbgse	238	12	reliable	reliable	JJ
cord-005603-kjcbbgse	238	13	method	method	NN
cord-005603-kjcbbgse	238	14	for	for	IN
cord-005603-kjcbbgse	238	15	identifying	identify	VBG
cord-005603-kjcbbgse	238	16	patients	patient	NNS
cord-005603-kjcbbgse	238	17	having	have	VBG
cord-005603-kjcbbgse	238	18	sepsis	sepsis	NN
cord-005603-kjcbbgse	238	19	among	among	IN
cord-005603-kjcbbgse	238	20	those	those	DT
cord-005603-kjcbbgse	238	21	presenting	present	VBG
cord-005603-kjcbbgse	238	22	with	with	IN
cord-005603-kjcbbgse	238	23	clinical	clinical	JJ
cord-005603-kjcbbgse	238	24	criteria	criterion	NNS
cord-005603-kjcbbgse	238	25	for	for	IN
cord-005603-kjcbbgse	238	26	SIRS/	SIRS/	NNP
cord-005603-kjcbbgse	238	27	sepsis	sepsis	NN
cord-005603-kjcbbgse	238	28	.	.	.
cord-005603-kjcbbgse	239	1	In	in	IN
cord-005603-kjcbbgse	239	2	this	this	DT
cord-005603-kjcbbgse	239	3	respect	respect	NN
cord-005603-kjcbbgse	239	4	,	,	,
cord-005603-kjcbbgse	239	5	the	the	DT
cord-005603-kjcbbgse	239	6	new	new	JJ
cord-005603-kjcbbgse	239	7	classification	classification	NN
cord-005603-kjcbbgse	239	8	has	have	VBZ
cord-005603-kjcbbgse	239	9	not	not	RB
cord-005603-kjcbbgse	239	10	provided	provide	VBN
cord-005603-kjcbbgse	239	11	a	a	DT
cord-005603-kjcbbgse	239	12	significant	significant	JJ
cord-005603-kjcbbgse	239	13	advance	advance	NN
cord-005603-kjcbbgse	239	14	in	in	IN
cord-005603-kjcbbgse	239	15	identifying	identify	VBG
cord-005603-kjcbbgse	239	16	at	at	IN
cord-005603-kjcbbgse	239	17	-	-	HYPH
cord-005603-kjcbbgse	239	18	risk	risk	NN
cord-005603-kjcbbgse	239	19	patients	patient	NNS
cord-005603-kjcbbgse	239	20	.	.	.
cord-005603-kjcbbgse	240	1	It	-PRON-	PRP
cord-005603-kjcbbgse	240	2	is	be	VBZ
cord-005603-kjcbbgse	240	3	noteworthy	noteworthy	JJ
cord-005603-kjcbbgse	240	4	that	that	IN
cord-005603-kjcbbgse	240	5	all	all	DT
cord-005603-kjcbbgse	240	6	recent	recent	JJ
cord-005603-kjcbbgse	240	7	clinical	clinical	JJ
cord-005603-kjcbbgse	240	8	trials	trial	NNS
cord-005603-kjcbbgse	240	9	have	have	VBP
cord-005603-kjcbbgse	240	10	actually	actually	RB
cord-005603-kjcbbgse	240	11	used	use	VBN
cord-005603-kjcbbgse	240	12	criteria	criterion	NNS
cord-005603-kjcbbgse	240	13	for	for	IN
cord-005603-kjcbbgse	240	14	severe	severe	JJ
cord-005603-kjcbbgse	240	15	sepsis	sepsis	NN
cord-005603-kjcbbgse	240	16	or	or	CC
cord-005603-kjcbbgse	240	17	shock	shock	NN
cord-005603-kjcbbgse	240	18	in	in	IN
cord-005603-kjcbbgse	240	19	their	-PRON-	PRP$
cord-005603-kjcbbgse	240	20	inclusion	inclusion	NN
cord-005603-kjcbbgse	240	21	criteria	criterion	NNS
cord-005603-kjcbbgse	240	22	.	.	.
cord-005603-kjcbbgse	241	1	If	if	IN
cord-005603-kjcbbgse	241	2	this	this	DT
cord-005603-kjcbbgse	241	3	classification	classification	NN
cord-005603-kjcbbgse	241	4	is	be	VBZ
cord-005603-kjcbbgse	241	5	used	use	VBN
cord-005603-kjcbbgse	241	6	,	,	,
cord-005603-kjcbbgse	241	7	and	and	CC
cord-005603-kjcbbgse	241	8	there	there	EX
cord-005603-kjcbbgse	241	9	is	be	VBZ
cord-005603-kjcbbgse	241	10	a	a	DT
cord-005603-kjcbbgse	241	11	need	need	NN
cord-005603-kjcbbgse	241	12	for	for	IN
cord-005603-kjcbbgse	241	13	studying	study	VBG
cord-005603-kjcbbgse	241	14	patients	patient	NNS
cord-005603-kjcbbgse	241	15	at	at	IN
cord-005603-kjcbbgse	241	16	an	an	DT
cord-005603-kjcbbgse	241	17	early	early	JJ
cord-005603-kjcbbgse	241	18	stage	stage	NN
cord-005603-kjcbbgse	241	19	of	of	IN
cord-005603-kjcbbgse	241	20	infection	infection	NN
cord-005603-kjcbbgse	241	21	,	,	,
cord-005603-kjcbbgse	241	22	then	then	RB
cord-005603-kjcbbgse	241	23	a	a	DT
cord-005603-kjcbbgse	241	24	more	more	RBR
cord-005603-kjcbbgse	241	25	in	in	IN
cord-005603-kjcbbgse	241	26	-	-	HYPH
cord-005603-kjcbbgse	241	27	depth	depth	NN
cord-005603-kjcbbgse	241	28	analysis	analysis	NN
cord-005603-kjcbbgse	241	29	of	of	IN
cord-005603-kjcbbgse	241	30	risk	risk	NN
cord-005603-kjcbbgse	241	31	factors	factor	NNS
cord-005603-kjcbbgse	241	32	for	for	IN
cord-005603-kjcbbgse	241	33	sepsis	sepsis	NN
cord-005603-kjcbbgse	241	34	or	or	CC
cord-005603-kjcbbgse	241	35	its	-PRON-	PRP$
cord-005603-kjcbbgse	241	36	more	more	RBR
cord-005603-kjcbbgse	241	37	severe	severe	JJ
cord-005603-kjcbbgse	241	38	forms	form	NNS
cord-005603-kjcbbgse	241	39	in	in	IN
cord-005603-kjcbbgse	241	40	patients	patient	NNS
cord-005603-kjcbbgse	241	41	with	with	IN
cord-005603-kjcbbgse	241	42	SIRS	SIRS	NNP
cord-005603-kjcbbgse	241	43	patients	patient	NNS
cord-005603-kjcbbgse	241	44	is	be	VBZ
cord-005603-kjcbbgse	241	45	needed	need	VBN
cord-005603-kjcbbgse	241	46	.	.	.
cord-005603-kjcbbgse	242	1	Septic	septic	JJ
cord-005603-kjcbbgse	242	2	shock	shock	NN
cord-005603-kjcbbgse	242	3	remains	remain	VBZ
cord-005603-kjcbbgse	242	4	a	a	DT
cord-005603-kjcbbgse	242	5	major	major	JJ
cord-005603-kjcbbgse	242	6	prognostic	prognostic	JJ
cord-005603-kjcbbgse	242	7	factor	factor	NN
cord-005603-kjcbbgse	242	8	and	and	CC
cord-005603-kjcbbgse	242	9	,	,	,
cord-005603-kjcbbgse	242	10	importantly	importantly	RB
cord-005603-kjcbbgse	242	11	,	,	,
cord-005603-kjcbbgse	242	12	is	be	VBZ
cord-005603-kjcbbgse	242	13	readily	readily	RB
cord-005603-kjcbbgse	242	14	available	available	JJ
cord-005603-kjcbbgse	242	15	for	for	IN
cord-005603-kjcbbgse	242	16	stratification	stratification	NN
cord-005603-kjcbbgse	242	17	at	at	IN
cord-005603-kjcbbgse	242	18	inclusion	inclusion	NN
cord-005603-kjcbbgse	242	19	of	of	IN
cord-005603-kjcbbgse	242	20	patients	patient	NNS
cord-005603-kjcbbgse	242	21	into	into	IN
cord-005603-kjcbbgse	242	22	clinical	clinical	JJ
cord-005603-kjcbbgse	242	23	trials	trial	NNS
cord-005603-kjcbbgse	242	24	.	.	.
cord-005603-kjcbbgse	243	1	A	a	DT
cord-005603-kjcbbgse	243	2	general	general	JJ
cord-005603-kjcbbgse	243	3	severity	severity	NN
cord-005603-kjcbbgse	243	4	score	score	NN
cord-005603-kjcbbgse	243	5	(	(	-LRB-
cord-005603-kjcbbgse	243	6	original	original	JJ
cord-005603-kjcbbgse	243	7	or	or	CC
cord-005603-kjcbbgse	243	8	customised	customised	JJ
cord-005603-kjcbbgse	243	9	)	)	-RRB-
cord-005603-kjcbbgse	243	10	could	could	MD
cord-005603-kjcbbgse	243	11	also	also	RB
cord-005603-kjcbbgse	243	12	be	be	VB
cord-005603-kjcbbgse	243	13	used	use	VBN
cord-005603-kjcbbgse	243	14	,	,	,
cord-005603-kjcbbgse	243	15	or	or	CC
cord-005603-kjcbbgse	243	16	better	well	JJR
cord-005603-kjcbbgse	243	17	,	,	,
cord-005603-kjcbbgse	243	18	an	an	DT
cord-005603-kjcbbgse	243	19	organ	organ	NN
cord-005603-kjcbbgse	243	20	dysfunction	dysfunction	NN
cord-005603-kjcbbgse	243	21	score	score	NN
cord-005603-kjcbbgse	243	22	,	,	,
cord-005603-kjcbbgse	243	23	depending	depend	VBG
cord-005603-kjcbbgse	243	24	on	on	IN
cord-005603-kjcbbgse	243	25	objectives	objective	NNS
cord-005603-kjcbbgse	243	26	and	and	CC
cord-005603-kjcbbgse	243	27	end	end	NN
cord-005603-kjcbbgse	243	28	-	-	HYPH
cord-005603-kjcbbgse	243	29	points	point	NNS
cord-005603-kjcbbgse	243	30	pursued	pursue	VBN
cord-005603-kjcbbgse	243	31	in	in	IN
cord-005603-kjcbbgse	243	32	the	the	DT
cord-005603-kjcbbgse	243	33	trial	trial	NN
cord-005603-kjcbbgse	243	34	.	.	.
cord-005603-kjcbbgse	244	1	Consideration	consideration	NN
cord-005603-kjcbbgse	244	2	should	should	MD
cord-005603-kjcbbgse	244	3	also	also	RB
cord-005603-kjcbbgse	244	4	be	be	VB
cord-005603-kjcbbgse	244	5	given	give	VBN
cord-005603-kjcbbgse	244	6	to	to	IN
cord-005603-kjcbbgse	244	7	major	major	JJ
cord-005603-kjcbbgse	244	8	underlying	underlying	JJ
cord-005603-kjcbbgse	244	9	conditions	condition	NNS
cord-005603-kjcbbgse	244	10	,	,	,
cord-005603-kjcbbgse	244	11	using	use	VBG
cord-005603-kjcbbgse	244	12	a	a	DT
cord-005603-kjcbbgse	244	13	simple	simple	JJ
cord-005603-kjcbbgse	244	14	index	index	NN
cord-005603-kjcbbgse	244	15	,	,	,
cord-005603-kjcbbgse	244	16	such	such	JJ
cord-005603-kjcbbgse	244	17	as	as	IN
cord-005603-kjcbbgse	244	18	the	the	DT
cord-005603-kjcbbgse	244	19	MacCabe	MacCabe	NNP
cord-005603-kjcbbgse	244	20	score	score	NN
cord-005603-kjcbbgse	244	21	.	.	.
cord-005603-kjcbbgse	245	1	It	-PRON-	PRP
cord-005603-kjcbbgse	245	2	is	be	VBZ
cord-005603-kjcbbgse	245	3	apparent	apparent	JJ
cord-005603-kjcbbgse	245	4	that	that	IN
cord-005603-kjcbbgse	245	5	the	the	DT
cord-005603-kjcbbgse	245	6	systemic	systemic	JJ
cord-005603-kjcbbgse	245	7	response	response	NN
cord-005603-kjcbbgse	245	8	to	to	IN
cord-005603-kjcbbgse	245	9	infection	infection	NN
cord-005603-kjcbbgse	245	10	,	,	,
cord-005603-kjcbbgse	245	11	not	not	RB
cord-005603-kjcbbgse	245	12	infection	infection	NN
cord-005603-kjcbbgse	245	13	itself	-PRON-	PRP
cord-005603-kjcbbgse	245	14	,	,	,
cord-005603-kjcbbgse	245	15	is	be	VBZ
cord-005603-kjcbbgse	245	16	the	the	DT
cord-005603-kjcbbgse	245	17	major	major	JJ
cord-005603-kjcbbgse	245	18	determinant	determinant	NN
cord-005603-kjcbbgse	245	19	of	of	IN
cord-005603-kjcbbgse	245	20	the	the	DT
cord-005603-kjcbbgse	245	21	outcome	outcome	NN
cord-005603-kjcbbgse	245	22	of	of	IN
cord-005603-kjcbbgse	245	23	patients	patient	NNS
cord-005603-kjcbbgse	245	24	.	.	.
cord-005603-kjcbbgse	246	1	Mortality	mortality	NN
cord-005603-kjcbbgse	246	2	remains	remain	VBZ
cord-005603-kjcbbgse	246	3	the	the	DT
cord-005603-kjcbbgse	246	4	reference	reference	NN
cord-005603-kjcbbgse	246	5	endpoint	endpoint	NN
cord-005603-kjcbbgse	246	6	.	.	.
cord-005603-kjcbbgse	247	1	This	this	DT
cord-005603-kjcbbgse	247	2	simple	simple	JJ
cord-005603-kjcbbgse	247	3	and	and	CC
cord-005603-kjcbbgse	247	4	robust	robust	JJ
cord-005603-kjcbbgse	247	5	end	end	NN
cord-005603-kjcbbgse	247	6	-	-	HYPH
cord-005603-kjcbbgse	247	7	point	point	NN
cord-005603-kjcbbgse	247	8	is	be	VBZ
cord-005603-kjcbbgse	247	9	validated	validate	VBN
cord-005603-kjcbbgse	247	10	by	by	IN
cord-005603-kjcbbgse	247	11	the	the	DT
cord-005603-kjcbbgse	247	12	fact	fact	NN
cord-005603-kjcbbgse	247	13	that	that	IN
cord-005603-kjcbbgse	247	14	mortality	mortality	NN
cord-005603-kjcbbgse	247	15	remains	remain	VBZ
cord-005603-kjcbbgse	247	16	high	high	JJ
cord-005603-kjcbbgse	247	17	,	,	,
cord-005603-kjcbbgse	247	18	at	at	IN
cord-005603-kjcbbgse	247	19	least	least	JJS
cord-005603-kjcbbgse	247	20	in	in	IN
cord-005603-kjcbbgse	247	21	the	the	DT
cord-005603-kjcbbgse	247	22	most	most	RBS
cord-005603-kjcbbgse	247	23	severe	severe	JJ
cord-005603-kjcbbgse	247	24	forms	form	NNS
cord-005603-kjcbbgse	247	25	of	of	IN
cord-005603-kjcbbgse	247	26	the	the	DT
cord-005603-kjcbbgse	247	27	septic	septic	JJ
cord-005603-kjcbbgse	247	28	syndromes	syndrome	NNS
cord-005603-kjcbbgse	247	29	,	,	,
cord-005603-kjcbbgse	247	30	and	and	CC
cord-005603-kjcbbgse	247	31	by	by	IN
cord-005603-kjcbbgse	247	32	the	the	DT
cord-005603-kjcbbgse	247	33	estimated	estimate	VBN
cord-005603-kjcbbgse	247	34	attributable	attributable	JJ
cord-005603-kjcbbgse	247	35	mortality	mortality	NN
cord-005603-kjcbbgse	247	36	which	which	WDT
cord-005603-kjcbbgse	247	37	is	be	VBZ
cord-005603-kjcbbgse	247	38	also	also	RB
cord-005603-kjcbbgse	247	39	very	very	RB
cord-005603-kjcbbgse	247	40	high	high	JJ
cord-005603-kjcbbgse	247	41	,	,	,
cord-005603-kjcbbgse	247	42	and	and	CC
cord-005603-kjcbbgse	247	43	likely	likely	JJ
cord-005603-kjcbbgse	247	44	accounts	account	NNS
cord-005603-kjcbbgse	247	45	for	for	IN
cord-005603-kjcbbgse	247	46	two	two	CD
cord-005603-kjcbbgse	247	47	-	-	HYPH
cord-005603-kjcbbgse	247	48	thirds	third	NNS
cord-005603-kjcbbgse	247	49	of	of	IN
cord-005603-kjcbbgse	247	50	the	the	DT
cord-005603-kjcbbgse	247	51	overall	overall	JJ
cord-005603-kjcbbgse	247	52	mortality	mortality	NN
cord-005603-kjcbbgse	247	53	,	,	,
cord-005603-kjcbbgse	247	54	especially	especially	RB
cord-005603-kjcbbgse	247	55	of	of	IN
cord-005603-kjcbbgse	247	56	the	the	DT
cord-005603-kjcbbgse	247	57	short	short	JJ
cord-005603-kjcbbgse	247	58	-	-	HYPH
cord-005603-kjcbbgse	247	59	term	term	NN
cord-005603-kjcbbgse	247	60	mortality	mortality	NN
cord-005603-kjcbbgse	247	61	.	.	.
cord-005603-kjcbbgse	248	1	Since	since	IN
cord-005603-kjcbbgse	248	2	sepsis	sepsis	NN
cord-005603-kjcbbgse	248	3	has	have	VBZ
cord-005603-kjcbbgse	248	4	also	also	RB
cord-005603-kjcbbgse	248	5	substantial	substantial	JJ
cord-005603-kjcbbgse	248	6	effects	effect	NNS
cord-005603-kjcbbgse	248	7	on	on	IN
cord-005603-kjcbbgse	248	8	long	long	JJ
cord-005603-kjcbbgse	248	9	-	-	HYPH
cord-005603-kjcbbgse	248	10	term	term	NN
cord-005603-kjcbbgse	248	11	survival	survival	NN
cord-005603-kjcbbgse	248	12	,	,	,
cord-005603-kjcbbgse	248	13	a	a	DT
cord-005603-kjcbbgse	248	14	longer	long	JJR
cord-005603-kjcbbgse	248	15	than	than	IN
cord-005603-kjcbbgse	248	16	usual	usual	JJ
cord-005603-kjcbbgse	248	17	follow	follow	NN
cord-005603-kjcbbgse	248	18	-	-	HYPH
cord-005603-kjcbbgse	248	19	up	up	NN
cord-005603-kjcbbgse	248	20	(	(	-LRB-
cord-005603-kjcbbgse	248	21	i.	i.	NNP
cord-005603-kjcbbgse	248	22	e.	e.	NNP
cord-005603-kjcbbgse	248	23	,	,	,
cord-005603-kjcbbgse	248	24	6	6	CD
cord-005603-kjcbbgse	248	25	months	month	NNS
cord-005603-kjcbbgse	248	26	to	to	IN
cord-005603-kjcbbgse	248	27	1	1	CD
cord-005603-kjcbbgse	248	28	year	year	NN
cord-005603-kjcbbgse	248	29	)	)	-RRB-
cord-005603-kjcbbgse	248	30	should	should	MD
cord-005603-kjcbbgse	248	31	be	be	VB
cord-005603-kjcbbgse	248	32	used	use	VBN
cord-005603-kjcbbgse	248	33	,	,	,
cord-005603-kjcbbgse	248	34	at	at	IN
cord-005603-kjcbbgse	248	35	least	least	JJS
cord-005603-kjcbbgse	248	36	if	if	IN
cord-005603-kjcbbgse	248	37	some	some	DT
cord-005603-kjcbbgse	248	38	possible	possible	JJ
cord-005603-kjcbbgse	248	39	delayed	delay	VBN
cord-005603-kjcbbgse	248	40	effects	effect	NNS
cord-005603-kjcbbgse	248	41	of	of	IN
cord-005603-kjcbbgse	248	42	therapy	therapy	NN
cord-005603-kjcbbgse	248	43	on	on	IN
cord-005603-kjcbbgse	248	44	survival	survival	NN
cord-005603-kjcbbgse	248	45	are	be	VBP
cord-005603-kjcbbgse	248	46	expected	expect	VBN
cord-005603-kjcbbgse	248	47	.	.	.
cord-005603-kjcbbgse	249	1	Using	use	VBG
cord-005603-kjcbbgse	249	2	mortality	mortality	NN
cord-005603-kjcbbgse	249	3	as	as	IN
cord-005603-kjcbbgse	249	4	an	an	DT
cord-005603-kjcbbgse	249	5	end	end	NN
cord-005603-kjcbbgse	249	6	-	-	HYPH
cord-005603-kjcbbgse	249	7	point	point	NN
cord-005603-kjcbbgse	249	8	implies	imply	VBZ
cord-005603-kjcbbgse	249	9	that	that	IN
cord-005603-kjcbbgse	249	10	factors	factor	NNS
cord-005603-kjcbbgse	249	11	other	other	JJ
cord-005603-kjcbbgse	249	12	than	than	IN
cord-005603-kjcbbgse	249	13	sepsis	sepsis	NN
cord-005603-kjcbbgse	249	14	itself	-PRON-	PRP
cord-005603-kjcbbgse	249	15	,	,	,
cord-005603-kjcbbgse	249	16	which	which	WDT
cord-005603-kjcbbgse	249	17	have	have	VBP
cord-005603-kjcbbgse	249	18	a	a	DT
cord-005603-kjcbbgse	249	19	significant	significant	JJ
cord-005603-kjcbbgse	249	20	impact	impact	NN
cord-005603-kjcbbgse	249	21	on	on	IN
cord-005603-kjcbbgse	249	22	patients	patient	NNS
cord-005603-kjcbbgse	249	23	'	'	POS
cord-005603-kjcbbgse	249	24	survival	survival	NN
cord-005603-kjcbbgse	249	25	,	,	,
cord-005603-kjcbbgse	249	26	are	be	VBP
cord-005603-kjcbbgse	249	27	accounted	account	VBN
cord-005603-kjcbbgse	249	28	for	for	IN
cord-005603-kjcbbgse	249	29	in	in	IN
cord-005603-kjcbbgse	249	30	the	the	DT
cord-005603-kjcbbgse	249	31	survival	survival	NN
cord-005603-kjcbbgse	249	32	analysis	analysis	NN
cord-005603-kjcbbgse	249	33	.	.	.
cord-005603-kjcbbgse	250	1	These	these	DT
cord-005603-kjcbbgse	250	2	factors	factor	NNS
cord-005603-kjcbbgse	250	3	include	include	VBP
cord-005603-kjcbbgse	250	4	,	,	,
cord-005603-kjcbbgse	250	5	(	(	-LRB-
cord-005603-kjcbbgse	250	6	but	but	CC
cord-005603-kjcbbgse	250	7	may	may	MD
cord-005603-kjcbbgse	250	8	not	not	RB
cord-005603-kjcbbgse	250	9	be	be	VB
cord-005603-kjcbbgse	250	10	limited	limit	VBN
cord-005603-kjcbbgse	250	11	to	to	IN
cord-005603-kjcbbgse	250	12	)	)	-RRB-
cord-005603-kjcbbgse	251	1	the	the	DT
cord-005603-kjcbbgse	251	2	severity	severity	NN
cord-005603-kjcbbgse	251	3	of	of	IN
cord-005603-kjcbbgse	251	4	the	the	DT
cord-005603-kjcbbgse	251	5	underlying	underlie	VBG
cord-005603-kjcbbgse	251	6	disease	disease	NN
cord-005603-kjcbbgse	251	7	,	,	,
cord-005603-kjcbbgse	251	8	the	the	DT
cord-005603-kjcbbgse	251	9	presence	presence	NN
cord-005603-kjcbbgse	251	10	of	of	IN
cord-005603-kjcbbgse	251	11	comorbidities	comorbiditie	NNS
cord-005603-kjcbbgse	251	12	,	,	,
cord-005603-kjcbbgse	251	13	and	and	CC
cord-005603-kjcbbgse	251	14	the	the	DT
cord-005603-kjcbbgse	251	15	severity	severity	NN
cord-005603-kjcbbgse	251	16	of	of	IN
cord-005603-kjcbbgse	251	17	haemodynamic	haemodynamic	JJ
cord-005603-kjcbbgse	251	18	disturbances	disturbance	NNS
cord-005603-kjcbbgse	251	19	and	and	CC
cord-005603-kjcbbgse	251	20	other	other	JJ
cord-005603-kjcbbgse	251	21	organ	organ	NN
cord-005603-kjcbbgse	251	22	dysfunction	dysfunction	NN
cord-005603-kjcbbgse	251	23	at	at	IN
cord-005603-kjcbbgse	251	24	inclusion	inclusion	NN
cord-005603-kjcbbgse	251	25	.	.	.
cord-005603-kjcbbgse	252	1	The	the	DT
cord-005603-kjcbbgse	252	2	importance	importance	NN
cord-005603-kjcbbgse	252	3	of	of	IN
cord-005603-kjcbbgse	252	4	underlying	underlying	JJ
cord-005603-kjcbbgse	252	5	conditions	condition	NNS
cord-005603-kjcbbgse	252	6	is	be	VBZ
cord-005603-kjcbbgse	252	7	highlighted	highlight	VBN
cord-005603-kjcbbgse	252	8	by	by	IN
cord-005603-kjcbbgse	252	9	the	the	DT
cord-005603-kjcbbgse	252	10	relatively	relatively	RB
cord-005603-kjcbbgse	252	11	low	low	JJ
cord-005603-kjcbbgse	252	12	spontaneous	spontaneous	JJ
cord-005603-kjcbbgse	252	13	life	life	NN
cord-005603-kjcbbgse	252	14	expectancy	expectancy	NN
cord-005603-kjcbbgse	252	15	associated	associate	VBN
cord-005603-kjcbbgse	252	16	with	with	IN
cord-005603-kjcbbgse	252	17	underlying	underlie	VBG
cord-005603-kjcbbgse	252	18	illness	illness	NN
cord-005603-kjcbbgse	252	19	and	and	CC
cord-005603-kjcbbgse	252	20	comorbidities	comorbiditie	NNS
cord-005603-kjcbbgse	252	21	in	in	IN
cord-005603-kjcbbgse	252	22	most	most	JJS
cord-005603-kjcbbgse	252	23	patients	patient	NNS
cord-005603-kjcbbgse	252	24	with	with	IN
cord-005603-kjcbbgse	252	25	sepsis	sepsis	NN
cord-005603-kjcbbgse	252	26	.	.	.
cord-005603-kjcbbgse	253	1	It	-PRON-	PRP
cord-005603-kjcbbgse	253	2	has	have	VBZ
cord-005603-kjcbbgse	253	3	been	be	VBN
cord-005603-kjcbbgse	253	4	suggested	suggest	VBN
cord-005603-kjcbbgse	253	5	that	that	IN
cord-005603-kjcbbgse	253	6	the	the	DT
cord-005603-kjcbbgse	253	7	assessment	assessment	NN
cord-005603-kjcbbgse	253	8	of	of	IN
cord-005603-kjcbbgse	253	9	organ	organ	NN
cord-005603-kjcbbgse	253	10	dysfunction	dysfunction	NN
cord-005603-kjcbbgse	253	11	/	/	SYM
cord-005603-kjcbbgse	253	12	failure	failure	NN
cord-005603-kjcbbgse	253	13	,	,	,
cord-005603-kjcbbgse	253	14	especially	especially	RB
cord-005603-kjcbbgse	253	15	via	via	IN
cord-005603-kjcbbgse	253	16	a	a	DT
cord-005603-kjcbbgse	253	17	grading	grading	NN
cord-005603-kjcbbgse	253	18	score	score	NN
cord-005603-kjcbbgse	253	19	could	could	MD
cord-005603-kjcbbgse	253	20	be	be	VB
cord-005603-kjcbbgse	253	21	used	use	VBN
cord-005603-kjcbbgse	253	22	as	as	IN
cord-005603-kjcbbgse	253	23	a	a	DT
cord-005603-kjcbbgse	253	24	substitute	substitute	NN
cord-005603-kjcbbgse	253	25	for	for	IN
cord-005603-kjcbbgse	253	26	mortality	mortality	NN
cord-005603-kjcbbgse	253	27	.	.	.
cord-005603-kjcbbgse	254	1	This	this	DT
cord-005603-kjcbbgse	254	2	debate	debate	NN
cord-005603-kjcbbgse	254	3	is	be	VBZ
cord-005603-kjcbbgse	254	4	at	at	IN
cord-005603-kjcbbgse	254	5	present	present	JJ
cord-005603-kjcbbgse	254	6	unsettled	unsettled	JJ
cord-005603-kjcbbgse	254	7	.	.	.
cord-005603-kjcbbgse	255	1	Clearly	clearly	RB
cord-005603-kjcbbgse	255	2	,	,	,
cord-005603-kjcbbgse	255	3	organ	organ	NN
cord-005603-kjcbbgse	255	4	dysfunctions	dysfunction	NNS
cord-005603-kjcbbgse	255	5	are	be	VBP
cord-005603-kjcbbgse	255	6	strongly	strongly	RB
cord-005603-kjcbbgse	255	7	(	(	-LRB-
cord-005603-kjcbbgse	255	8	linearly	linearly	RB
cord-005603-kjcbbgse	255	9	)	)	-RRB-
cord-005603-kjcbbgse	255	10	related	relate	VBN
cord-005603-kjcbbgse	255	11	to	to	IN
cord-005603-kjcbbgse	255	12	mortality	mortality	NN
cord-005603-kjcbbgse	255	13	,	,	,
cord-005603-kjcbbgse	255	14	and	and	CC
cord-005603-kjcbbgse	255	15	there	there	EX
cord-005603-kjcbbgse	255	16	is	be	VBZ
cord-005603-kjcbbgse	255	17	no	no	DT
cord-005603-kjcbbgse	255	18	obvious	obvious	JJ
cord-005603-kjcbbgse	255	19	advantage	advantage	NN
cord-005603-kjcbbgse	255	20	from	from	IN
cord-005603-kjcbbgse	255	21	using	use	VBG
cord-005603-kjcbbgse	255	22	such	such	PDT
cord-005603-kjcbbgse	255	23	a	a	DT
cord-005603-kjcbbgse	255	24	score	score	NN
cord-005603-kjcbbgse	255	25	instead	instead	RB
cord-005603-kjcbbgse	255	26	of	of	IN
cord-005603-kjcbbgse	255	27	mortality	mortality	NN
cord-005603-kjcbbgse	255	28	.	.	.
cord-005603-kjcbbgse	256	1	Using	use	VBG
cord-005603-kjcbbgse	256	2	organ	organ	NN
cord-005603-kjcbbgse	256	3	failure	failure	NN
cord-005603-kjcbbgse	256	4	-	-	HYPH
cord-005603-kjcbbgse	256	5	free	free	JJ
cord-005603-kjcbbgse	256	6	days	day	NNS
cord-005603-kjcbbgse	256	7	,	,	,
cord-005603-kjcbbgse	256	8	as	as	IN
cord-005603-kjcbbgse	256	9	suggested	suggest	VBN
cord-005603-kjcbbgse	256	10	when	when	WRB
cord-005603-kjcbbgse	256	11	dealing	deal	VBG
cord-005603-kjcbbgse	256	12	with	with	IN
cord-005603-kjcbbgse	256	13	one	one	CD
cord-005603-kjcbbgse	256	14	organ	organ	NN
cord-005603-kjcbbgse	256	15	system	system	NN
cord-005603-kjcbbgse	256	16	dysfunction	dysfunction	NN
cord-005603-kjcbbgse	256	17	such	such	JJ
cord-005603-kjcbbgse	256	18	as	as	IN
cord-005603-kjcbbgse	256	19	ARDS	ARDS	NNP
cord-005603-kjcbbgse	256	20	,	,	,
cord-005603-kjcbbgse	256	21	may	may	MD
cord-005603-kjcbbgse	256	22	be	be	VB
cord-005603-kjcbbgse	256	23	misleading	mislead	VBG
cord-005603-kjcbbgse	256	24	,	,	,
cord-005603-kjcbbgse	256	25	as	as	IN
cord-005603-kjcbbgse	256	26	death	death	NN
cord-005603-kjcbbgse	256	27	may	may	MD
cord-005603-kjcbbgse	256	28	still	still	RB
cord-005603-kjcbbgse	256	29	occur	occur	VB
cord-005603-kjcbbgse	256	30	relatively	relatively	RB
cord-005603-kjcbbgse	256	31	late	late	JJ
cord-005603-kjcbbgse	256	32	after	after	IN
cord-005603-kjcbbgse	256	33	onset	onset	NN
cord-005603-kjcbbgse	256	34	of	of	IN
cord-005603-kjcbbgse	256	35	sepsis	sepsis	NN
cord-005603-kjcbbgse	256	36	.	.	.
cord-005603-kjcbbgse	257	1	At	at	IN
cord-005603-kjcbbgse	257	2	present	present	JJ
cord-005603-kjcbbgse	257	3	,	,	,
cord-005603-kjcbbgse	257	4	organ	organ	NN
cord-005603-kjcbbgse	257	5	failure	failure	NN
cord-005603-kjcbbgse	257	6	scores	score	NNS
cord-005603-kjcbbgse	257	7	are	be	VBP
cord-005603-kjcbbgse	257	8	best	well	RBS
cord-005603-kjcbbgse	257	9	used	use	VBN
cord-005603-kjcbbgse	257	10	as	as	IN
cord-005603-kjcbbgse	257	11	adjustment	adjustment	NN
cord-005603-kjcbbgse	257	12	variables	variable	NNS
cord-005603-kjcbbgse	257	13	at	at	IN
cord-005603-kjcbbgse	257	14	onset	onset	NN
cord-005603-kjcbbgse	257	15	of	of	IN
cord-005603-kjcbbgse	257	16	sepsis	sepsis	NN
cord-005603-kjcbbgse	257	17	and	and	CC
cord-005603-kjcbbgse	257	18	their	-PRON-	PRP$
cord-005603-kjcbbgse	257	19	assessment	assessment	NN
cord-005603-kjcbbgse	257	20	over	over	IN
cord-005603-kjcbbgse	257	21	time	time	NN
cord-005603-kjcbbgse	257	22	should	should	MD
cord-005603-kjcbbgse	257	23	be	be	VB
cord-005603-kjcbbgse	257	24	viewed	view	VBN
cord-005603-kjcbbgse	257	25	as	as	IN
cord-005603-kjcbbgse	257	26	explanatory	explanatory	JJ
cord-005603-kjcbbgse	257	27	observations	observation	NNS
cord-005603-kjcbbgse	257	28	in	in	IN
cord-005603-kjcbbgse	257	29	an	an	DT
cord-005603-kjcbbgse	257	30	attempt	attempt	NN
cord-005603-kjcbbgse	257	31	to	to	TO
cord-005603-kjcbbgse	257	32	provide	provide	VB
cord-005603-kjcbbgse	257	33	better	well	JJR
cord-005603-kjcbbgse	257	34	insight	insight	NN
cord-005603-kjcbbgse	257	35	into	into	IN
cord-005603-kjcbbgse	257	36	the	the	DT
cord-005603-kjcbbgse	257	37	physiological	physiological	JJ
cord-005603-kjcbbgse	257	38	effects	effect	NNS
cord-005603-kjcbbgse	257	39	of	of	IN
cord-005603-kjcbbgse	257	40	interventions	intervention	NNS
cord-005603-kjcbbgse	257	41	.	.	.
cord-005603-kjcbbgse	258	1	The	the	DT
cord-005603-kjcbbgse	258	2	American	american	JJ
cord-005603-kjcbbgse	258	3	-	-	HYPH
cord-005603-kjcbbgse	258	4	European	european	JJ
cord-005603-kjcbbgse	258	5	consensus	consensus	NN
cord-005603-kjcbbgse	258	6	conference	conference	NN
cord-005603-kjcbbgse	258	7	on	on	IN
cord-005603-kjcbbgse	258	8	ARDS	ARDS	NNP
cord-005603-kjcbbgse	258	9	:	:	:
cord-005603-kjcbbgse	258	10	definitions	definition	NNS
cord-005603-kjcbbgse	258	11	,	,	,
cord-005603-kjcbbgse	258	12	mechanisms	mechanism	NNS
cord-005603-kjcbbgse	258	13	,	,	,
cord-005603-kjcbbgse	258	14	relevant	relevant	JJ
cord-005603-kjcbbgse	258	15	outcomes	outcome	NNS
cord-005603-kjcbbgse	258	16	and	and	CC
cord-005603-kjcbbgse	258	17	clinical	clinical	JJ
cord-005603-kjcbbgse	258	18	trials	trial	NNS
cord-005603-kjcbbgse	258	19	coordination	coordination	NN
cord-005603-kjcbbgse	258	20	Definitions	definition	NNS
cord-005603-kjcbbgse	258	21	for	for	IN
cord-005603-kjcbbgse	258	22	sepsis	sepsis	NN
cord-005603-kjcbbgse	258	23	and	and	CC
cord-005603-kjcbbgse	258	24	organ	organ	NN
cord-005603-kjcbbgse	258	25	failure	failure	NN
cord-005603-kjcbbgse	258	26	and	and	CC
cord-005603-kjcbbgse	258	27	guidelines	guideline	NNS
cord-005603-kjcbbgse	258	28	for	for	IN
cord-005603-kjcbbgse	258	29	the	the	DT
cord-005603-kjcbbgse	258	30	use	use	NN
cord-005603-kjcbbgse	258	31	of	of	IN
cord-005603-kjcbbgse	258	32	innovative	innovative	JJ
cord-005603-kjcbbgse	258	33	therapies	therapy	NNS
cord-005603-kjcbbgse	258	34	in	in	IN
cord-005603-kjcbbgse	258	35	sepsis	sepsis	NN
cord-005603-kjcbbgse	258	36	Increase	increase	NN
cord-005603-kjcbbgse	258	37	in	in	IN
cord-005603-kjcbbgse	258	38	national	national	JJ
cord-005603-kjcbbgse	258	39	hospital	hospital	NN
cord-005603-kjcbbgse	258	40	discharge	discharge	NN
cord-005603-kjcbbgse	258	41	survey	survey	NN
cord-005603-kjcbbgse	258	42	rates	rate	NNS
cord-005603-kjcbbgse	258	43	for	for	IN
cord-005603-kjcbbgse	258	44	septicemia	septicemia	NN
cord-005603-kjcbbgse	258	45	±	±	NNP
cord-005603-kjcbbgse	258	46	United	United	NNP
cord-005603-kjcbbgse	258	47	States	States	NNP
cord-005603-kjcbbgse	258	48	Nosocomial	Nosocomial	NNP
cord-005603-kjcbbgse	258	49	bloodstream	bloodstream	NN
cord-005603-kjcbbgse	258	50	infections	infection	NNS
cord-005603-kjcbbgse	258	51	.	.	.
cord-005603-kjcbbgse	259	1	Secular	secular	JJ
cord-005603-kjcbbgse	259	2	trends	trend	NNS
cord-005603-kjcbbgse	259	3	in	in	IN
cord-005603-kjcbbgse	259	4	rates	rate	NNS
cord-005603-kjcbbgse	259	5	,	,	,
cord-005603-kjcbbgse	259	6	mortality	mortality	NN
cord-005603-kjcbbgse	259	7	,	,	,
cord-005603-kjcbbgse	259	8	and	and	CC
cord-005603-kjcbbgse	259	9	contribution	contribution	NN
cord-005603-kjcbbgse	259	10	to	to	IN
cord-005603-kjcbbgse	259	11	total	total	JJ
cord-005603-kjcbbgse	259	12	hospital	hospital	NN
cord-005603-kjcbbgse	259	13	deaths	death	NNS
cord-005603-kjcbbgse	259	14	Bacteremia	Bacteremia	NNP
cord-005603-kjcbbgse	259	15	and	and	CC
cord-005603-kjcbbgse	259	16	severe	severe	JJ
cord-005603-kjcbbgse	259	17	sepsis	sepsis	NN
cord-005603-kjcbbgse	259	18	in	in	IN
cord-005603-kjcbbgse	259	19	adults	adult	NNS
cord-005603-kjcbbgse	259	20	:	:	:
cord-005603-kjcbbgse	259	21	A	a	DT
cord-005603-kjcbbgse	259	22	multicenter	multicenter	JJ
cord-005603-kjcbbgse	259	23	prospective	prospective	JJ
cord-005603-kjcbbgse	259	24	survey	survey	NN
cord-005603-kjcbbgse	259	25	in	in	IN
cord-005603-kjcbbgse	259	26	ICUs	ICUs	NNP
cord-005603-kjcbbgse	259	27	and	and	CC
cord-005603-kjcbbgse	259	28	wards	ward	NNS
cord-005603-kjcbbgse	259	29	of	of	IN
cord-005603-kjcbbgse	259	30	24	24	CD
cord-005603-kjcbbgse	259	31	hospitals	hospital	NNS
cord-005603-kjcbbgse	260	1	The	the	DT
cord-005603-kjcbbgse	260	2	natural	natural	JJ
cord-005603-kjcbbgse	260	3	history	history	NN
cord-005603-kjcbbgse	260	4	of	of	IN
cord-005603-kjcbbgse	260	5	the	the	DT
cord-005603-kjcbbgse	260	6	systemic	systemic	JJ
cord-005603-kjcbbgse	260	7	inflammatory	inflammatory	JJ
cord-005603-kjcbbgse	260	8	response	response	NN
cord-005603-kjcbbgse	260	9	syndrome	syndrome	NN
cord-005603-kjcbbgse	261	1	The	the	DT
cord-005603-kjcbbgse	261	2	dynamics	dynamic	NNS
cord-005603-kjcbbgse	261	3	of	of	IN
cord-005603-kjcbbgse	261	4	disease	disease	NN
cord-005603-kjcbbgse	261	5	progression	progression	NN
cord-005603-kjcbbgse	261	6	in	in	IN
cord-005603-kjcbbgse	261	7	sepsis	sepsis	NN
cord-005603-kjcbbgse	261	8	:	:	:
cord-005603-kjcbbgse	261	9	Markov	Markov	NNP
cord-005603-kjcbbgse	261	10	modeling	modeling	NN
cord-005603-kjcbbgse	261	11	describing	describe	VBG
cord-005603-kjcbbgse	261	12	the	the	DT
cord-005603-kjcbbgse	261	13	natural	natural	JJ
cord-005603-kjcbbgse	261	14	history	history	NN
cord-005603-kjcbbgse	261	15	and	and	CC
cord-005603-kjcbbgse	261	16	the	the	DT
cord-005603-kjcbbgse	261	17	likely	likely	JJ
cord-005603-kjcbbgse	261	18	impact	impact	NN
cord-005603-kjcbbgse	261	19	of	of	IN
cord-005603-kjcbbgse	261	20	effective	effective	JJ
cord-005603-kjcbbgse	261	21	antisepsis	antisepsis	NN
cord-005603-kjcbbgse	261	22	agents	agent	NNS
cord-005603-kjcbbgse	261	23	Epidemiology	Epidemiology	NNP
cord-005603-kjcbbgse	261	24	of	of	IN
cord-005603-kjcbbgse	261	25	sepsis	sepsis	NN
cord-005603-kjcbbgse	261	26	syndrome	syndrome	NN
cord-005603-kjcbbgse	261	27	in	in	IN
cord-005603-kjcbbgse	261	28	8	8	CD
cord-005603-kjcbbgse	261	29	academic	academic	JJ
cord-005603-kjcbbgse	261	30	medical	medical	JJ
cord-005603-kjcbbgse	261	31	centers	center	NNS
cord-005603-kjcbbgse	261	32	Systemic	systemic	JJ
cord-005603-kjcbbgse	261	33	inflammatory	inflammatory	JJ
cord-005603-kjcbbgse	261	34	response	response	NN
cord-005603-kjcbbgse	261	35	syndrome	syndrome	NN
cord-005603-kjcbbgse	261	36	,	,	,
cord-005603-kjcbbgse	261	37	sepsis	sepsis	NN
cord-005603-kjcbbgse	261	38	,	,	,
cord-005603-kjcbbgse	261	39	severe	severe	JJ
cord-005603-kjcbbgse	261	40	sepsis	sepsis	NN
cord-005603-kjcbbgse	261	41	and	and	CC
cord-005603-kjcbbgse	261	42	septic	septic	JJ
cord-005603-kjcbbgse	261	43	shock	shock	NN
cord-005603-kjcbbgse	261	44	:	:	:
cord-005603-kjcbbgse	261	45	incidence	incidence	NN
cord-005603-kjcbbgse	261	46	,	,	,
cord-005603-kjcbbgse	261	47	morbidities	morbidity	NNS
cord-005603-kjcbbgse	261	48	and	and	CC
cord-005603-kjcbbgse	261	49	outcomes	outcome	NNS
cord-005603-kjcbbgse	261	50	in	in	IN
cord-005603-kjcbbgse	261	51	surgical	surgical	JJ
cord-005603-kjcbbgse	261	52	ICU	ICU	NNP
cord-005603-kjcbbgse	261	53	patients	patient	NNS
cord-005603-kjcbbgse	261	54	Role	role	NN
cord-005603-kjcbbgse	261	55	of	of	IN
cord-005603-kjcbbgse	261	56	systemic	systemic	JJ
cord-005603-kjcbbgse	261	57	inflammatory	inflammatory	JJ
cord-005603-kjcbbgse	261	58	response	response	NN
cord-005603-kjcbbgse	261	59	syndrome	syndrome	NN
cord-005603-kjcbbgse	261	60	and	and	CC
cord-005603-kjcbbgse	261	61	infection	infection	NN
cord-005603-kjcbbgse	261	62	in	in	IN
cord-005603-kjcbbgse	261	63	the	the	DT
cord-005603-kjcbbgse	261	64	occurrence	occurrence	NN
cord-005603-kjcbbgse	261	65	of	of	IN
cord-005603-kjcbbgse	261	66	early	early	JJ
cord-005603-kjcbbgse	261	67	multiple	multiple	JJ
cord-005603-kjcbbgse	261	68	organ	organ	NN
cord-005603-kjcbbgse	261	69	dysfunction	dysfunction	NN
cord-005603-kjcbbgse	261	70	syndrome	syndrome	NN
cord-005603-kjcbbgse	261	71	following	follow	VBG
cord-005603-kjcbbgse	261	72	severe	severe	JJ
cord-005603-kjcbbgse	261	73	trauma	trauma	NN
cord-005603-kjcbbgse	261	74	American	American	NNP
cord-005603-kjcbbgse	261	75	College	College	NNP
cord-005603-kjcbbgse	261	76	of	of	IN
cord-005603-kjcbbgse	261	77	Chest	Chest	NNP
cord-005603-kjcbbgse	261	78	Physicians/	Physicians/	NNP
cord-005603-kjcbbgse	261	79	Society	Society	NNP
cord-005603-kjcbbgse	261	80	of	of	IN
cord-005603-kjcbbgse	261	81	Critical	Critical	NNP
cord-005603-kjcbbgse	261	82	Care	Care	NNP
cord-005603-kjcbbgse	261	83	Medicine	Medicine	NNP
cord-005603-kjcbbgse	261	84	Consensus	Consensus	NNP
cord-005603-kjcbbgse	261	85	Conference	Conference	NNP
cord-005603-kjcbbgse	261	86	definitions	definition	NNS
cord-005603-kjcbbgse	261	87	of	of	IN
cord-005603-kjcbbgse	261	88	the	the	DT
cord-005603-kjcbbgse	261	89	systemic	systemic	JJ
cord-005603-kjcbbgse	261	90	inflammatory	inflammatory	JJ
cord-005603-kjcbbgse	261	91	response	response	NN
cord-005603-kjcbbgse	261	92	syndrome	syndrome	NN
cord-005603-kjcbbgse	261	93	and	and	CC
cord-005603-kjcbbgse	261	94	allied	ally	VBN
cord-005603-kjcbbgse	261	95	disorders	disorder	NNS
cord-005603-kjcbbgse	261	96	in	in	IN
cord-005603-kjcbbgse	261	97	relation	relation	NN
cord-005603-kjcbbgse	261	98	to	to	IN
cord-005603-kjcbbgse	261	99	critically	critically	RB
cord-005603-kjcbbgse	261	100	injured	injure	VBN
cord-005603-kjcbbgse	261	101	patients	patient	NNS
cord-005603-kjcbbgse	262	1	The	the	DT
cord-005603-kjcbbgse	262	2	Italian	italian	JJ
cord-005603-kjcbbgse	262	3	SEPSIS	SEPSIS	NNP
cord-005603-kjcbbgse	262	4	study	study	NN
cord-005603-kjcbbgse	262	5	:	:	:
cord-005603-kjcbbgse	263	1	Preliminary	preliminary	JJ
cord-005603-kjcbbgse	263	2	results	result	NNS
cord-005603-kjcbbgse	263	3	on	on	IN
cord-005603-kjcbbgse	263	4	the	the	DT
cord-005603-kjcbbgse	263	5	incidence	incidence	NN
cord-005603-kjcbbgse	263	6	and	and	CC
cord-005603-kjcbbgse	263	7	evolution	evolution	NN
cord-005603-kjcbbgse	263	8	of	of	IN
cord-005603-kjcbbgse	263	9	SIRS	sirs	NN
cord-005603-kjcbbgse	263	10	,	,	,
cord-005603-kjcbbgse	263	11	sepsis	sepsis	NN
cord-005603-kjcbbgse	263	12	,	,	,
cord-005603-kjcbbgse	263	13	severe	severe	JJ
cord-005603-kjcbbgse	263	14	sepsis	sepsis	NN
cord-005603-kjcbbgse	263	15	and	and	CC
cord-005603-kjcbbgse	263	16	septic	septic	JJ
cord-005603-kjcbbgse	263	17	shock	shock	NN
cord-005603-kjcbbgse	263	18	Incidence	incidence	NN
cord-005603-kjcbbgse	263	19	,	,	,
cord-005603-kjcbbgse	263	20	risk	risk	NN
cord-005603-kjcbbgse	263	21	factors	factor	NNS
cord-005603-kjcbbgse	263	22	,	,	,
cord-005603-kjcbbgse	263	23	and	and	CC
cord-005603-kjcbbgse	263	24	outcome	outcome	NN
cord-005603-kjcbbgse	263	25	of	of	IN
cord-005603-kjcbbgse	263	26	severe	severe	JJ
cord-005603-kjcbbgse	263	27	sepsis	sepsis	NN
cord-005603-kjcbbgse	263	28	and	and	CC
cord-005603-kjcbbgse	263	29	septic	septic	JJ
cord-005603-kjcbbgse	263	30	shock	shock	NN
cord-005603-kjcbbgse	263	31	in	in	IN
cord-005603-kjcbbgse	263	32	adults	adult	NNS
cord-005603-kjcbbgse	263	33	.	.	.
cord-005603-kjcbbgse	264	1	A	a	DT
cord-005603-kjcbbgse	264	2	multicenter	multicenter	JJ
cord-005603-kjcbbgse	264	3	prospective	prospective	JJ
cord-005603-kjcbbgse	264	4	study	study	NN
cord-005603-kjcbbgse	264	5	in	in	IN
cord-005603-kjcbbgse	264	6	intensive	intensive	JJ
cord-005603-kjcbbgse	264	7	care	care	NN
cord-005603-kjcbbgse	264	8	units	unit	NNS
cord-005603-kjcbbgse	264	9	Predicting	predict	VBG
cord-005603-kjcbbgse	264	10	bacteremia	bacteremia	NN
cord-005603-kjcbbgse	264	11	in	in	IN
cord-005603-kjcbbgse	264	12	patients	patient	NNS
cord-005603-kjcbbgse	264	13	with	with	IN
cord-005603-kjcbbgse	264	14	sepsis	sepsis	NN
cord-005603-kjcbbgse	264	15	syndrome	syndrome	NN
cord-005603-kjcbbgse	265	1	The	the	DT
cord-005603-kjcbbgse	265	2	sepsis	sepsis	NN
cord-005603-kjcbbgse	265	3	syndrome	syndrome	NN
cord-005603-kjcbbgse	265	4	in	in	IN
cord-005603-kjcbbgse	265	5	a	a	DT
cord-005603-kjcbbgse	265	6	Dutch	Dutch	NNP
cord-005603-kjcbbgse	265	7	University	University	NNP
cord-005603-kjcbbgse	265	8	Hospital	Hospital	NNP
cord-005603-kjcbbgse	265	9	.	.	.
cord-005603-kjcbbgse	266	1	Clinical	clinical	JJ
cord-005603-kjcbbgse	266	2	observations	observation	NNS
cord-005603-kjcbbgse	266	3	the	the	DT
cord-005603-kjcbbgse	266	4	Departement	Departement	NNP
cord-005603-kjcbbgse	266	5	of	of	IN
cord-005603-kjcbbgse	266	6	Veterans	Veterans	NNP
cord-005603-kjcbbgse	266	7	Affairs	Affairs	NNPS
cord-005603-kjcbbgse	266	8	Sepsis	Sepsis	NNP
cord-005603-kjcbbgse	266	9	Cooperative	Cooperative	NNP
cord-005603-kjcbbgse	266	10	Studies	Studies	NNPS
cord-005603-kjcbbgse	266	11	Group	Group	NNP
cord-005603-kjcbbgse	266	12	(	(	-LRB-
cord-005603-kjcbbgse	266	13	1997	1997	CD
cord-005603-kjcbbgse	266	14	)	)	-RRB-
cord-005603-kjcbbgse	267	1	Magnitude	magnitude	NN
cord-005603-kjcbbgse	267	2	and	and	CC
cord-005603-kjcbbgse	267	3	duration	duration	NN
cord-005603-kjcbbgse	267	4	of	of	IN
cord-005603-kjcbbgse	267	5	the	the	DT
cord-005603-kjcbbgse	267	6	effect	effect	NN
cord-005603-kjcbbgse	267	7	of	of	IN
cord-005603-kjcbbgse	267	8	sepsis	sepsis	NN
cord-005603-kjcbbgse	267	9	on	on	IN
cord-005603-kjcbbgse	267	10	survival	survival	NN
cord-005603-kjcbbgse	267	11	Bedside	Bedside	NNP
cord-005603-kjcbbgse	267	12	prediction	prediction	NN
cord-005603-kjcbbgse	267	13	of	of	IN
cord-005603-kjcbbgse	267	14	mortality	mortality	NN
cord-005603-kjcbbgse	267	15	from	from	IN
cord-005603-kjcbbgse	267	16	bacteremic	bacteremic	JJ
cord-005603-kjcbbgse	267	17	sepsis	sepsis	NN
cord-005603-kjcbbgse	267	18	.	.	.
cord-005603-kjcbbgse	268	1	A	a	DT
cord-005603-kjcbbgse	268	2	dynamic	dynamic	JJ
cord-005603-kjcbbgse	268	3	analysis	analysis	NN
cord-005603-kjcbbgse	268	4	of	of	IN
cord-005603-kjcbbgse	268	5	ICU	ICU	NNP
cord-005603-kjcbbgse	268	6	patients	patient	NNS
cord-005603-kjcbbgse	268	7	Wagner	Wagner	NNP
cord-005603-kjcbbgse	268	8	DP	DP	NNP
cord-005603-kjcbbgse	268	9	(	(	-LRB-
cord-005603-kjcbbgse	268	10	1992	1992	CD
cord-005603-kjcbbgse	268	11	)	)	-RRB-
cord-005603-kjcbbgse	268	12	Evaluation	evaluation	NN
cord-005603-kjcbbgse	268	13	of	of	IN
cord-005603-kjcbbgse	268	14	definitions	definition	NNS
cord-005603-kjcbbgse	268	15	for	for	IN
cord-005603-kjcbbgse	268	16	sepsis	sepsis	NN
cord-005603-kjcbbgse	268	17	Gram	gram	NN
cord-005603-kjcbbgse	268	18	-	-	HYPH
cord-005603-kjcbbgse	268	19	negative	negative	JJ
cord-005603-kjcbbgse	268	20	bacteremia	bacteremia	NN
cord-005603-kjcbbgse	268	21	.	.	.
cord-005603-kjcbbgse	269	1	IV	IV	NNP
cord-005603-kjcbbgse	269	2	.	.	.
cord-005603-kjcbbgse	270	1	Re	re	NN
cord-005603-kjcbbgse	270	2	-	-	NN
cord-005603-kjcbbgse	270	3	evaluation	evaluation	NN
cord-005603-kjcbbgse	270	4	of	of	IN
cord-005603-kjcbbgse	270	5	clinical	clinical	JJ
cord-005603-kjcbbgse	270	6	features	feature	NNS
cord-005603-kjcbbgse	270	7	and	and	CC
cord-005603-kjcbbgse	270	8	treatment	treatment	NN
cord-005603-kjcbbgse	270	9	in	in	IN
cord-005603-kjcbbgse	270	10	612	612	CD
cord-005603-kjcbbgse	270	11	patients	patient	NNS
cord-005603-kjcbbgse	270	12	Long	long	JJ
cord-005603-kjcbbgse	270	13	-	-	HYPH
cord-005603-kjcbbgse	270	14	term	term	NN
cord-005603-kjcbbgse	270	15	survival	survival	NN
cord-005603-kjcbbgse	270	16	and	and	CC
cord-005603-kjcbbgse	270	17	function	function	NN
cord-005603-kjcbbgse	270	18	after	after	IN
cord-005603-kjcbbgse	270	19	suspected	suspect	VBN
cord-005603-kjcbbgse	270	20	gram	gram	NN
cord-005603-kjcbbgse	270	21	-	-	HYPH
cord-005603-kjcbbgse	270	22	negative	negative	JJ
cord-005603-kjcbbgse	270	23	sepsis	sepsis	NN
cord-005603-kjcbbgse	270	24	Importance	importance	NN
cord-005603-kjcbbgse	270	25	of	of	IN
cord-005603-kjcbbgse	270	26	pre	pre	JJ
cord-005603-kjcbbgse	270	27	-	-	JJ
cord-005603-kjcbbgse	270	28	existing	existing	JJ
cord-005603-kjcbbgse	270	29	comorbidities	comorbiditie	NNS
cord-005603-kjcbbgse	270	30	for	for	IN
cord-005603-kjcbbgse	270	31	prognosis	prognosis	NN
cord-005603-kjcbbgse	270	32	of	of	IN
cord-005603-kjcbbgse	270	33	septicemia	septicemia	NN
cord-005603-kjcbbgse	270	34	in	in	IN
cord-005603-kjcbbgse	270	35	critically	critically	RB
cord-005603-kjcbbgse	270	36	ill	ill	JJ
cord-005603-kjcbbgse	270	37	patients	patient	NNS
cord-005603-kjcbbgse	271	1	A	a	DT
cord-005603-kjcbbgse	271	2	new	new	JJ
cord-005603-kjcbbgse	271	3	simplified	simplified	JJ
cord-005603-kjcbbgse	271	4	acute	acute	JJ
cord-005603-kjcbbgse	271	5	physiology	physiology	NN
cord-005603-kjcbbgse	271	6	score	score	NN
cord-005603-kjcbbgse	271	7	(	(	-LRB-
cord-005603-kjcbbgse	271	8	SAPS	SAPS	NNP
cord-005603-kjcbbgse	271	9	II	II	NNP
cord-005603-kjcbbgse	271	10	)	)	-RRB-
cord-005603-kjcbbgse	271	11	based	base	VBN
cord-005603-kjcbbgse	271	12	on	on	IN
cord-005603-kjcbbgse	271	13	a	a	DT
cord-005603-kjcbbgse	271	14	European	european	JJ
cord-005603-kjcbbgse	271	15	-	-	HYPH
cord-005603-kjcbbgse	271	16	North	north	JJ
cord-005603-kjcbbgse	271	17	American	american	JJ
cord-005603-kjcbbgse	271	18	multicenter	multicenter	JJ
cord-005603-kjcbbgse	271	19	study	study	NN
cord-005603-kjcbbgse	272	1	The	the	DT
cord-005603-kjcbbgse	272	2	clinical	clinical	JJ
cord-005603-kjcbbgse	272	3	evaluation	evaluation	NN
cord-005603-kjcbbgse	272	4	of	of	IN
cord-005603-kjcbbgse	272	5	new	new	JJ
cord-005603-kjcbbgse	272	6	drugs	drug	NNS
cord-005603-kjcbbgse	272	7	for	for	IN
cord-005603-kjcbbgse	272	8	sepsis	sepsis	NN
cord-005603-kjcbbgse	272	9	:	:	:
cord-005603-kjcbbgse	272	10	a	a	DT
cord-005603-kjcbbgse	272	11	prospective	prospective	JJ
cord-005603-kjcbbgse	272	12	study	study	NN
cord-005603-kjcbbgse	272	13	design	design	NN
cord-005603-kjcbbgse	272	14	based	base	VBN
cord-005603-kjcbbgse	272	15	on	on	IN
cord-005603-kjcbbgse	272	16	survival	survival	NN
cord-005603-kjcbbgse	272	17	analysis	analysis	NN
cord-005603-kjcbbgse	273	1	The	the	DT
cord-005603-kjcbbgse	273	2	ICU	ICU	NNP
cord-005603-kjcbbgse	273	3	Scoring	Scoring	NNP
cord-005603-kjcbbgse	273	4	Group	Group	NNP
cord-005603-kjcbbgse	273	5	(	(	-LRB-
cord-005603-kjcbbgse	273	6	1995	1995	CD
cord-005603-kjcbbgse	273	7	)	)	-RRB-
cord-005603-kjcbbgse	274	1	Customized	customized	JJ
cord-005603-kjcbbgse	274	2	probability	probability	NN
cord-005603-kjcbbgse	274	3	models	model	NNS
cord-005603-kjcbbgse	274	4	for	for	IN
cord-005603-kjcbbgse	274	5	early	early	JJ
cord-005603-kjcbbgse	274	6	severe	severe	JJ
cord-005603-kjcbbgse	274	7	sepsis	sepsis	NN
cord-005603-kjcbbgse	274	8	in	in	IN
cord-005603-kjcbbgse	274	9	adult	adult	NN
cord-005603-kjcbbgse	274	10	intensive	intensive	JJ
cord-005603-kjcbbgse	274	11	care	care	NN
cord-005603-kjcbbgse	274	12	patients	patient	NNS
cord-005603-kjcbbgse	275	1	The	the	DT
cord-005603-kjcbbgse	275	2	Phase	Phase	NNP
cord-005603-kjcbbgse	275	3	III	III	NNP
cord-005603-kjcbbgse	275	4	rhIL-1ra	rhIL-1ra	NNS
cord-005603-kjcbbgse	276	1	Sepsis	Sepsis	NNP
cord-005603-kjcbbgse	276	2	Study	Study	NNP
cord-005603-kjcbbgse	276	3	Group	Group	NNP
cord-005603-kjcbbgse	276	4	(	(	-LRB-
cord-005603-kjcbbgse	276	5	1994	1994	CD
cord-005603-kjcbbgse	276	6	)	)	-RRB-
cord-005603-kjcbbgse	277	1	Recombinant	recombinant	JJ
cord-005603-kjcbbgse	277	2	human	human	JJ
cord-005603-kjcbbgse	277	3	interleukin-1	interleukin-1	NNP
cord-005603-kjcbbgse	277	4	receptor	receptor	NN
cord-005603-kjcbbgse	277	5	antagonist	antagonist	NN
cord-005603-kjcbbgse	277	6	in	in	IN
cord-005603-kjcbbgse	277	7	the	the	DT
cord-005603-kjcbbgse	277	8	treatment	treatment	NN
cord-005603-kjcbbgse	277	9	of	of	IN
cord-005603-kjcbbgse	277	10	patients	patient	NNS
cord-005603-kjcbbgse	277	11	with	with	IN
cord-005603-kjcbbgse	277	12	sepsis	sepsis	NN
cord-005603-kjcbbgse	277	13	syndrome	syndrome	NN
cord-005603-kjcbbgse	277	14	:	:	:
cord-005603-kjcbbgse	277	15	results	result	NNS
cord-005603-kjcbbgse	277	16	from	from	IN
cord-005603-kjcbbgse	277	17	a	a	DT
cord-005603-kjcbbgse	277	18	randomized	randomized	JJ
cord-005603-kjcbbgse	277	19	Prognosis	prognosis	NN
cord-005603-kjcbbgse	277	20	in	in	IN
cord-005603-kjcbbgse	277	21	acute	acute	JJ
cord-005603-kjcbbgse	277	22	organ	organ	NN
cord-005603-kjcbbgse	277	23	system	system	NN
cord-005603-kjcbbgse	277	24	failure	failure	NN
cord-005603-kjcbbgse	278	1	The	the	DT
cord-005603-kjcbbgse	278	2	ICU	ICU	NNP
cord-005603-kjcbbgse	278	3	Scoring	Scoring	NNP
cord-005603-kjcbbgse	278	4	Group	Group	NNP
cord-005603-kjcbbgse	278	5	(	(	-LRB-
cord-005603-kjcbbgse	278	6	1996	1996	CD
cord-005603-kjcbbgse	278	7	)	)	-RRB-
cord-005603-kjcbbgse	279	1	The	the	DT
cord-005603-kjcbbgse	279	2	logistic	logistic	JJ
cord-005603-kjcbbgse	279	3	organ	organ	NN
cord-005603-kjcbbgse	279	4	dysfunction	dysfunction	NN
cord-005603-kjcbbgse	279	5	system	system	NN
cord-005603-kjcbbgse	279	6	:	:	:
cord-005603-kjcbbgse	279	7	A	a	DT
cord-005603-kjcbbgse	279	8	new	new	JJ
cord-005603-kjcbbgse	279	9	way	way	NN
cord-005603-kjcbbgse	279	10	to	to	TO
cord-005603-kjcbbgse	279	11	assess	assess	VB
cord-005603-kjcbbgse	279	12	organ	organ	NN
cord-005603-kjcbbgse	279	13	dysfunction	dysfunction	NN
cord-005603-kjcbbgse	279	14	in	in	IN
cord-005603-kjcbbgse	279	15	the	the	DT
cord-005603-kjcbbgse	279	16	intensive	intensive	JJ
cord-005603-kjcbbgse	279	17	care	care	NN
cord-005603-kjcbbgse	279	18	unit	unit	NN
cord-005603-kjcbbgse	279	19	Multiple	multiple	JJ
cord-005603-kjcbbgse	279	20	organ	organ	NN
cord-005603-kjcbbgse	279	21	dysfunction	dysfunction	NN
cord-005603-kjcbbgse	279	22	score	score	NN
cord-005603-kjcbbgse	279	23	:	:	:
cord-005603-kjcbbgse	279	24	A	a	DT
cord-005603-kjcbbgse	279	25	reliable	reliable	JJ
cord-005603-kjcbbgse	279	26	descriptor	descriptor	NN
cord-005603-kjcbbgse	279	27	of	of	IN
cord-005603-kjcbbgse	279	28	a	a	DT
cord-005603-kjcbbgse	279	29	complex	complex	JJ
cord-005603-kjcbbgse	279	30	clinical	clinical	JJ
cord-005603-kjcbbgse	279	31	outcome	outcome	NN
cord-005603-kjcbbgse	279	32	Use	use	NN
cord-005603-kjcbbgse	279	33	of	of	IN
cord-005603-kjcbbgse	279	34	the	the	DT
cord-005603-kjcbbgse	279	35	SOFA	sofa	NN
cord-005603-kjcbbgse	279	36	score	score	NN
cord-005603-kjcbbgse	279	37	to	to	TO
cord-005603-kjcbbgse	279	38	assess	assess	VB
cord-005603-kjcbbgse	279	39	the	the	DT
cord-005603-kjcbbgse	279	40	incidence	incidence	NN
cord-005603-kjcbbgse	279	41	of	of	IN
cord-005603-kjcbbgse	279	42	organ	organ	NN
cord-005603-kjcbbgse	279	43	dysfunction	dysfunction	NN
cord-005603-kjcbbgse	279	44	/	/	SYM
cord-005603-kjcbbgse	279	45	failure	failure	NN
cord-005603-kjcbbgse	279	46	in	in	IN
cord-005603-kjcbbgse	279	47	intensive	intensive	JJ
cord-005603-kjcbbgse	279	48	care	care	NN
cord-005603-kjcbbgse	279	49	units	unit	NNS
cord-005603-kjcbbgse	279	50	:	:	:
cord-005603-kjcbbgse	279	51	results	result	NNS
cord-005603-kjcbbgse	279	52	of	of	IN
cord-005603-kjcbbgse	279	53	a	a	DT
cord-005603-kjcbbgse	279	54	multicenter	multicenter	JJ
cord-005603-kjcbbgse	279	55	,	,	,
cord-005603-kjcbbgse	279	56	prospective	prospective	JJ
cord-005603-kjcbbgse	279	57	study	study	NN
cord-005603-kjcbbgse	279	58	Long	long	JJ
cord-005603-kjcbbgse	279	59	-	-	HYPH
cord-005603-kjcbbgse	279	60	term	term	NN
cord-005603-kjcbbgse	279	61	survival	survival	NN
cord-005603-kjcbbgse	279	62	after	after	IN
cord-005603-kjcbbgse	279	63	intensive	intensive	JJ
cord-005603-kjcbbgse	279	64	care	care	NN
cord-005603-kjcbbgse	279	65	unit	unit	NN
cord-005603-kjcbbgse	279	66	admission	admission	NN
cord-005603-kjcbbgse	279	67	with	with	IN
cord-005603-kjcbbgse	279	68	sepsis	sepsis	NN