id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-354384-bshj0w3o	Tanak, Ambalika S.	Multiplexed cytokine detection using electrochemical point-of-care sensing device towards rapid sepsis endotyping	2020-10-19		.txt	text/plain	6720	335	47	As a point-of-care treatment option, to date, no molecular host biomarker panel is available which makes an informed decision on the specific intervention based on the diagnosis of the immune response or the ability to detect improvements in the status of patients with sepsis (Albert-Vega et al., 2018; Gunsolus et al., 2019) . To address this technological gap this work demonstrates first-of-a-kind near-patient testing 'DETecT Sepsis' (Direct Electrochemical Technique Targeting Sepsis) sensor, which directly measures a panel of five host immune biomarkers in <5 minutes to guide the physician with active feedback on patient immune status for better therapeutic administration. The advantages of the DETecT Sepsis sensor over existing point-of-care tests are: (i) direct hassle-free measurement from a single drop of undiluted blood plasma; (ii) allows sepsis stratification based on the body's hyper and hypo immune response; (iii) specifically surface engineered sensor design facilitates high sensitivity and specificity; (iv) portable handheld format enables multi-measure capabilities at near-patient testing.	./cache/cord-354384-bshj0w3o.txt	./txt/cord-354384-bshj0w3o.txt