id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-349076-x3rjasg0	Jarczak, Dominik	Use of Intravenous Immunoglobulins in Sepsis Therapy—A Clinical View	2020-08-03		.txt	text/plain	7023	347	37	With this review, we aim to provide an overview of the role of immunoglobulins, with emphasis on IgM-enriched formulations, in the therapy of adult patients with sepsis and septic shock. The clinical rationale for IVIg therapy in sepsis can be categorized as follows: the role of immunoglobulins in (i) recognition and clearance of pathogens and toxins, (ii) scavenging and inhibition of up-and downstream mediator gene transcription, and (iii) anti-apoptotic effects on immune cells. The clinical rationale for IVIg therapy in sepsis can be categorized as follows: the role of immunoglobulins in (i) recognition and clearance of pathogens and toxins, (ii) scavenging and inhibition of up-and downstream mediator gene transcription, and (iii) anti-apoptotic effects on immune cells. Relationship between the timing of administration of IgM and IgA enriched immunoglobulins in patients with severe sepsis and septic shock and the outcome: A retrospective analysis Effects of the timing of administration of IgM-and IgA-enriched intravenous polyclonal immunoglobulins on the outcome of septic shock patients	./cache/cord-349076-x3rjasg0.txt	./txt/cord-349076-x3rjasg0.txt