id author title date pages extension mime words sentences flesch summary cache txt cord-348785-f67amppy Kapicibaşi, Hasan Oğuz Pulmonary effects of ozone therapy at different doses combined with antibioticotherapy in experimental sepsis model 2020-07-13 .txt text/plain 2693 171 50 PURPOSE: This experimental sepsis model created with Escherichia coli aimed to investigate the histopathological effects of two different doses of ozone combined with antibiotherapy on lung tissue. Based on the known positive and negative effects of ozone, in our study we aimed to assess the effect of two different doses of ozone therapy added to antibiotic treatment in an experimental sepsis model induced with Escherichia coli on the histopathologic findings observed in the inflammatory process in the lungs. In an experimental necrotizing pancreatitis model, ozone therapy was seen to be more effective to reduce oxidative stress levels, tissue injury and bacterial translocation rates compared to hyperbaric oxygen treatment 30 . Data obtained as a result of our study lead to the consideration that ozone therapy administered in addition to antibiotherapy may cause negative effects on lung tissue damaged due to sepsis. ./cache/cord-348785-f67amppy.txt ./txt/cord-348785-f67amppy.txt