id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-297039-vfuem6bk	Beltrán-García, Jesús	Circular RNAs in Sepsis: Biogenesis, Function, and Clinical Significance	2020-06-25		.txt	text/plain	7502	468	46	Recent findings propose that circular RNAs (circRNAs) may play a prominent role in regulating the patients' immune system against different pathogens, including bacteria and viruses. Due to the role that circRNAs play in the modulation of different cytokines and immune proteins [62, 63] , altered states of alternative splicing in sepsis may alter the expression of circRNAs, which could partially explain the changes in the immune response of septic patients. However, circRNAs may play a key role in sepsis because of their ability to modulate different molecular mechanisms [10] , including inflammation [83] and immune response [62] , and to control multiple biological processes in metabolic organs (i.e., liver, pancreas [84] ) ( Figure 3 and Table 1 ). Interestingly, circRNAs may function as "molecular sponges", by controlling the expression of different types of non-coding RNAs, such as miRNAS, involved in regulating different processes in sepsis [105] [106] [107] [108] .	./cache/cord-297039-vfuem6bk.txt	./txt/cord-297039-vfuem6bk.txt