id author title date pages extension mime words sentences flesch summary cache txt cord-005603-kjcbbgse Brun-Buisson, C. The epidemiology of the systemic inflammatory response 2000 .txt text/plain 7166 297 48 Objective: To examine the incidence, risk factors, aetiologies and outcome of the various forms of the septic syndromes (the systemic inflammatory response syndrome [SIRS] sepsis, severe sepsis, and septic shock) and their relationships with infection.¶Design: Review of published cohort studies examining the epidemiology of the septic syndromes, with emphasis on intensive care unit (ICU) patients.¶Results: The prevalence of SIRS is very high, affecting one-third of all in-hospital patients, and > 50 % of all ICU patients; in surgical ICU patients, SIRS occurs in > 80 % patients. In the French Bacteraemia/Sepsis study, including 24 hospitals on the one hand [5] and 170 ICUs on the other [13] both surveyed during a 2-month period, the overall incidence of severe sepsis and shock (including clinically and microbiologically documented infection) was of 6/1000 of all hospital admissions, but only of 2.9/ 1000 in medical/surgical wards and 119/1000 in ICUs ( Table 2 ). ./cache/cord-005603-kjcbbgse.txt ./txt/cord-005603-kjcbbgse.txt