id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-001319-mlkaowqr	Giamarellos-Bourboulis, Evangelos J	Kinetics of circulating immunoglobulin M in sepsis: relationship with final outcome	2013-10-21		.txt	text/plain	3636	192	52	RESULTS: Serum IgM was decreased in septic shock compared to patients with systemic inflammatory response syndrome (SIRS) and patients with severe sepsis. The current study was designed in order to embed into the changes of circulating IgM levels of patients upon progression to the more severe stages of sepsis in relation with the production of IgM from circulating lymphocytes and with the final outcome. The primary endpoint was the over-time changes of IgM serum levels of patients upon progression to septic shock in relation with the final outcome that is survival or 28-day mortality. The study end point was the kinetics of serum IgM upon progression from severe sepsis to septic shock in relation with final outcome. The time curves of IgM were designed for 30 patients with severe sepsis who progressed into septic shock.	./cache/cord-001319-mlkaowqr.txt	./txt/cord-001319-mlkaowqr.txt