id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-355899-wd00f8cw	Dawson, E. D.	Multiplexed, Microscale, Microarray-based Serological Assay for Antibodies Against All Human-Relevant Coronaviruses	2020-09-04		.txt	text/plain	5841	294	48	This study reports on the VaxArray CoV SeroAssay linear dynamic range, limit of detection, specificity, reproducibility, accuracy, and investigates assay performance on a retrospective set of 263 blinded, de-identified human serum and plasma specimens to demonstrate positive and negative percent agreement to a mixed reference method of RT-PCR on a patient-matched specimen and collection date prior to the COVID-19 outbreak. A total of 132 serum samples known to be negative for the presence of antibodies to SARS-CoV-2 based on date of collection prior to December 2019, including 33 specimens from pediatric donors age 2-16, were analyzed via the standard VaxArray CoV SeroAssay procedure at a 1:100 dilution in PBB. To assess reproducibility and accuracy, a pooled human serum sample positive for antibodies to SARS-CoV-2, and also known to be reactive to the SARS antigen and the 4 endemic Table 3 shows the % CV in the back-calculated concentration value obtained on each relevant capture antigen for all 216 replicate measurements over all 3 days and all three lots of slides, with values ranging from 7 to 19 %CV for the 9 antigens.	./cache/cord-355899-wd00f8cw.txt	./txt/cord-355899-wd00f8cw.txt