id author title date pages extension mime words sentences flesch summary cache txt cord-355560-vsxe97xs Alves, Amanda Mandarino SARS-CoV-2 leading to Acute Pancreatitis: an unusual presentation 2020-09-15 .txt text/plain 1659 98 43 During SARS-CoV-2 (severe acute respiratory syndrome coronavirus-2) pandemic, the etiologic agent of COVID-19, several studies described the involvement of other tissues besides the respiratory tract, such as the gastrointestinal tract. Diagnosing acute pancreatitis secondary to SARS-CoV-2 infection is challenging due to the need to rule out other etiologies as well the notable heterogeneous presentations. The mechanisms of pancreatic injury in SARS-CoV-2 infection include direct cytopathic effects or indirect systemic inflammatory and immune-mediated cellular responses, resulting in organ damage or secondary enzyme abnormalities [1] . This case report describes a patient with COVID-19 that developed severe acute pancreatitis. ACE2 receptor is highly expressed in pancreatic islet cells [16] , therefore SARS-CoV-2 infection can theoretically cause islet damage resulting in acute diabetes [7] . ACE2 Expression in Pancreas May Cause Pancreatic Damage After SARS-CoV-2 Infection ./cache/cord-355560-vsxe97xs.txt ./txt/cord-355560-vsxe97xs.txt