id author title date pages extension mime words sentences flesch summary cache txt cord-353475-dtn7h1gj Haddad, Hazem miRNA target prediction might explain the reduced transmission of SARS-CoV-2 in Jordan, Middle East 2020-08-20 .txt text/plain 1462 103 64 In this work, via the miRDB database, we determined the target scores of predicted human miRNA to bind with the ss-RNA of the severe acute respiratory syndrome coronavirus (SARS-CoV-2) in general and its spike gene in specific. The exciting findings here that the nucleotide substitution 1841A > G at the viral genomic RNA level, which is an amino acid substation D614G at the spike protein level showed a change in the predicted miRNA sequence from hsa-miR-4793-5p to hsa-miR-3620-3p with an increase in the target score from 91 to 92. To understand the early steps of COVID-19 infection, we predicted miRNAs sequences targeting the submitted 29903bp of viral ss-RNA of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2 complete genomic RNA sequence) from the isolate of Wuhan-Hu-J o u r n a l P r e -p r o o f 1. ./cache/cord-353475-dtn7h1gj.txt ./txt/cord-353475-dtn7h1gj.txt