id author title date pages extension mime words sentences flesch summary cache txt cord-353373-zhkqnu0w Seidu, Samuel The impact of obesity on severe disease and mortality in people with SARS‐CoV‐2: A systematic review and meta‐analysis 2020-08-14 .txt text/plain 2872 159 50 BACKGROUND: Obesity accompanied by excess ectopic fat storage has been postulated as a risk factor for severe disease in people with SARS‐CoV‐2 through the stimulation of inflammation, functional immunologic deficit and a pro‐thrombotic disseminated intravascular coagulation with associated high rates of venous thromboembolism. METHODS: Observational studies in COVID‐19 patients reporting data on raised body mass index at admission and associated clinical outcomes were identified from MEDLINE, Embase, Web of Science and the Cochrane Library up to 16 May 2020. 2 Recent studies have increasingly described obesity as an associating factor for people at an increased risk of severe disease. 15 In order to attempt to quantify the relationship between raised body weight and severe outcomes from COVID-19, we conducted a systematic review and meta-analysis to determine whether people with overweight or obesity and with SARS-CoV-2 have different outcomes compared to those within normal weight thresholds. ./cache/cord-353373-zhkqnu0w.txt ./txt/cord-353373-zhkqnu0w.txt