id author title date pages extension mime words sentences flesch summary cache txt cord-353072-n92atcrx Kadkhoda, Kamran COVID-19: an Immunopathological View 2020-04-22 .txt text/plain 2045 107 45 Unravelling these mechanisms can assist basic scientists, laboratory medicine practitioners, clinicians, public health practitioners, funding agencies, and health care policymakers in responding to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic. This is consistent with high-level surface expression of angiotensin-converting enzyme 2 (ACE2), the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) receptor, on pneumocytes (2) . In the context of COVID-19, since ACE2 is highly expressed in the gastrointestinal (GI) tract (9), shedding the virus in the stool is prolonged (10); however, diarrhea is uncommon likely because virus-specific effector memory T cells typically home to the mucosal surfaces they had previously encountered with an infection with a common CoV, i.e., upper and lower respiratory tract. It has recently been shown that SARS-CoV and the Middle East respiratory syndrome (MERS)-CoV take advantage of non-or subneutralizing antibodies and enter cells via surface CD32a receptors (Trojan horse mechanism) (11, 12) . ./cache/cord-353072-n92atcrx.txt ./txt/cord-353072-n92atcrx.txt