id author title date pages extension mime words sentences flesch summary cache txt cord-351028-p5cq2is5 Yang, Jia-Wei Corticosteroid administration for viral pneumonia: COVID-19 and beyond 2020-06-27 .txt text/plain 1058 85 40 IMPLICATIONS: Observational studies showed that corticosteroid treatment was associated with increased mortality and nosocomial infections for influenza and delay virus clearance for SARS-CoV and MERS-CoV. Although clinical observational studies reported the improvement in symptoms and oxygenation for the severe COVID-19 patients received corticosteroids therapy, case fatality rate in the corticosteroid group was significantly higher than that in the non-corticosteroid group (69/443, 15.6% vs 56/1310, 4.3%). Although there is no evidence of corticosteroid therapy reduce the mortality of COVID-19 patients, some improvements in clinical symptoms and oxygenation were reported in some clinical observational studies. Corticosteroid therapy for 386 critically ill patients with the Middle East respiratory syndrome: a multicenter 387 retrospective cohort study Epidemiological and clinical characteristics of 432 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive 433 study Clinical course and outcomes of critically ill patients 449 with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, 450 observational study ./cache/cord-351028-p5cq2is5.txt ./txt/cord-351028-p5cq2is5.txt