id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-347965-zluu0i41	Essahib, Wafaa	SARS-CoV-2 host receptors ACE2 and CD147 (BSG) are present on human oocytes and blastocysts	2020-09-21		.txt	text/plain	1684	114	58	title: SARS-CoV-2 host receptors ACE2 and CD147 (BSG) are present on human oocytes and blastocysts PURPOSE: To visualize SARS-CoV-2 host receptors ACE2 and CD147 on human oocytes and blastocysts. RESULTS: SARS-CoV-2 host receptors ACE2 and CD147 are present on the membrane of trophectoderm, epiblast and hypoblast cells in human blastocysts. The aim of our study was to visualize SARS-CoV-2 receptors ACE2 and CD147 on human oocytes and blastocysts. In pre (5 days post fertilization (dpf5) and (dpf6))-and peri (dpf7)-implantation blastocysts, CD147 and ACE2 are present on the membrane of trophectoderm and hypoblast cells, which will both contribute to the embryonic part of the placenta (chorion). The presence of the receptors ACE2 and CD147, especially on the membrane, implicates that SARS-CoV-2 is theoretically able to bind and infect human oocytes and pre-and periimplantation embryos. Samples were washed in 2% BSA/PBS before Fig. 1 Immunofluorescent staining and confocal microscopy for SARS-CoV-2 host receptors ACE2 and CD147 on human oocytes and blastocysts.	./cache/cord-347965-zluu0i41.txt	./txt/cord-347965-zluu0i41.txt