id author title date pages extension mime words sentences flesch summary cache txt cord-347499-7q47jh14 Burrel, Sonia Co-infection of SARS-CoV-2 with other respiratory viruses and performance of lower respiratory tract samples for the diagnosis of COVID-19 2020-10-25 .txt text/plain 1353 75 51 METHODS: From January 25(th) through March 29(th), 2020, all URT and LRT samples collected from patients with suspected COVID-19 received in the virology laboratory of Pitié-Salpêtrière University Hospital (Paris, France) were tested simultaneously for SARS-CoV-2 and other respiratory viruses. In line with previous studies, different types of other respiratory viruses were detected together with SARS-CoV-2 among co-infected patients, including non-SARS-CoV-2 coronavirus, influenzavirus, adenovirus, rhinovirus/enterovirus, and parainfluenzavirus (Kim et al., 2020; Leuzinger et al., 2020; Lin et al., 2020a; Wee et al., 2020) . We evidenced the higher efficiency of LRT than URT samples for COVID-19 diagnosis, with a significantly higher rate of detection of SARS-CoV-2 and a 1 log-higher SARS-CoV-2 load for the majority of infected patients. In conclusion, the detection of other respiratory viruses in patients during epidemic period cannot rule out SARS-CoV-2 co-infection, and LRT samples increases the accuracy of diagnosis of viral respiratory infections, including COVID-19. ./cache/cord-347499-7q47jh14.txt ./txt/cord-347499-7q47jh14.txt