id author title date pages extension mime words sentences flesch summary cache txt cord-346291-qqy9ld94 Noroozi, Rezvan Altered cytokine levels and immune responses in patients with SARS-CoV-2 infection and related conditions 2020-05-21 .txt text/plain 1464 88 42 In the current review, we summarize the results of studies which reported alterations in cytokine levels and immune cell functions in patients affected with SARS-CoV-2 and related viruses. Alternatively named as the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus has been shown to induce various clinical manifestation in hosts ranging from asymptomatic conditions to severe symptoms including respiratory failure, shock, or multiorgan system dysfunction (1) Notably, this condition has been accompanied by a significant increase in the proportion of naïve helper T cells while reduction in memory helper T cells and regulatory T cells (5) . Notably, author reported significant over-production of IL-2, IL-7, IL-10, GCSF, IP-10, MCP1, MIP1A, and TNF-α in ICU patients compared with other group of SARS-CoV-2 infected persons (6) . Notably, T cell counts and cytokine concentrations in severe SARS-CoV-2 infected patients who stayed alive gradually returned to their levels in the mild cases. ./cache/cord-346291-qqy9ld94.txt ./txt/cord-346291-qqy9ld94.txt