id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-345493-3bb1zuqp	Itoyama, Satoru	Identification of an alternative 5′‐untranslated exon and new polymorphisms of angiotensin‐converting enzyme 2 gene: Lack of association with SARS in the Vietnamese population	2005-06-03		.txt	text/plain	3331	172	54	We analyzed genetic variations of angiotensin‐converting enzyme 2 (ACE2), considering that it might influence patients' susceptibility to severe acute respiratory syndrome‐associated coronavirus (SARS‐CoV) or development of SARS as a functional receptor. © 2005 Wiley‐Liss, Inc. We analyzed genetic variations of angiotensinconverting enzyme 2 (ACE2), considering that it might influence patients' susceptibility to severe acute respiratory syndrome-associated coronavirus (SARS-CoV) or development of SARS as a functional receptor. A case control study involving 44 SARS cases, 16 anti-SARS-CoV antibodypositive contacts, 87 antibody-negative contacts, and 50 non-contacts in Vietnam, failed to obtain any evidence that the ACE2 gene polymorphisms are involved in the disease process in the population. Using the PCR-based cloning procedure, we identified for the first time an alternative exon upstream of the original exon 1 of ACE2 that is expressed in various organs, including the lung and trachea, primary-cultured bronchial epithelial cells, and the small intestine.	./cache/cord-345493-3bb1zuqp.txt	./txt/cord-345493-3bb1zuqp.txt