id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-344842-9cfbb7p6	Coppola, Maurizio	Potential Unconventional Medicines for the Treatment of SARS-CoV-2	2020-05-19		.txt	text/plain	723	43	45	Adem and colleagues in their virtual screening based molecular docking study reported a potential binding affinity exerted by various bioflavonoids at the active site of the MPro, the main protease of the SARS-CoV-2 [1] . Potential inhibition properties were studied using the Molegro Virtual Docker Program and some flavonoids, in particular hesperidin, rutin, and diosmin showed a better affinity for the MPro than nelfinavir [1] . Rutin showed the second strongest binding energy at the active site of the MPro with a MoLDock score of −176.2740 and a HBond of −21.2402. Recently, Caly and colleagues reported a potential antiretroviral activity of the anti-parasitic agent ivermectin against SARS-CoV-2 virus. Despite the absence of clinical evidences regarding some potential anti-SARS-CoV-2 drugs, preliminar information reported by researchers suggest anyhow further studies in order to evaluate the clinical effects as well as the possibility to synthesize derivatives with stronger antiretroviral properties.	./cache/cord-344842-9cfbb7p6.txt	./txt/cord-344842-9cfbb7p6.txt