id author title date pages extension mime words sentences flesch summary cache txt cord-343836-daqrym0b Lange, Clemens Welche Bedeutung hat die Bindehaut als möglicher Übertragungsweg für eine SARS-CoV-2-Infektion? 2020-06-22 .txt text/plain 985 87 48 Recent studies suggest that COVID-19 patients rarely exhibit viral RNA in tear film and conjunctival smears and that, ACE2 and TMPRSS2 are only expressed in very small amounts in the conjunctiva, making conjunctival infection with SARS-CoV‑2 via these mediators unlikely. Es ist derzeit nicht eindeutig geklärt, ob Zellen der Augenoberfläche ACE2 oder TMPRSS2 exprimieren und damit für eine SARS-CoV-2-Infektion anfällig sind. The current body of evidence indicates that SARS-CoV-2 requires the membrane-bound angiotensinconverting enzyme 2 (ACE2) and the membrane-bound serine protease TMPRSS2 to enter cells. Recent studies suggest that COVID-19 patients rarely exhibit viral RNA in tear film and conjunctival smears and that, ACE2 and TMPRSS2 are only expressed in very small amounts in the conjunctiva, making conjunctival infection with SARS-CoV-2 via these mediators unlikely. ACE2 and TMPRSS2 are expressed on the human ocular surface, suggesting susceptibility to SARS-CoV-2 infection ./cache/cord-343836-daqrym0b.txt ./txt/cord-343836-daqrym0b.txt