id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-343148-rp3kmd80	Ayatollahi, Parisa	Possible Autoimmune Encephalitis with Claustrum Sign in case of Acute SARS-CoV-2 Infection	2020-09-17		.txt	text/plain	1029	68	40	title: Possible Autoimmune Encephalitis with Claustrum Sign in case of Acute SARS-CoV-2 Infection On the third day of admission, new behavioral changes appeared including elated mood, inappropriate laughing, anxiety, and insomnia, leading to treatment with clonazepam, risperidone, and sertraline, in addition to sodium divalproex. Repeat brain MRI showed signal hyperintensities on fluidattenuated inversion recovery (FLAIR) and T2-weighted sequences in the claustrum bilaterally, which were not present on the initial scan 2 weeks earlier. Follow-up MRI 1 month after the abnormal scan showed near-complete resolution of the claustrum hyperintensities ( Figure 2 ). [1] [2] [3] The MRI abnormality ("the claustrum sign") may extend to external/extreme capsules and insular cortices 3 and typically resolves in weeks or months. The finding of the claustrum sign on brain MRI, not previously reported in a COVID-19 patient, [4] [5] [6] [7] [8] provides further support for the idea that acute SARS-CoV-2 infection may present as an autoimmune encephalitis.	./cache/cord-343148-rp3kmd80.txt	./txt/cord-343148-rp3kmd80.txt