id author title date pages extension mime words sentences flesch summary cache txt cord-341976-yts6pzn3 Liu, Xintian Serum IgM against SARS-CoV-2 correlates with in-hospital mortality in severe/critical patients with COVID-19 in Wuhan, China 2020-07-06 .txt text/plain 3062 213 57 title: Serum IgM against SARS-CoV-2 correlates with in-hospital mortality in severe/critical patients with COVID-19 in Wuhan, China We conducted a single-center, retrospective, cohort study to investigate the relationship between serum immunoglobulin G (IgG) and IgM and clinical outcomes in severe/critical patients with COVID-19. Specific serum immunoglobulin G (IgG) and IgM against SARS-CoV or Middle East Respiratory Syndrome-coronavirus (MERS-CoV) became detectable in patients as early as 11-15 days post illness onset [11, 12] . AGING Additionally, the titers of IgM and IgG were significantly correlated with viral load in patients infected by SARS-CoV-2 in a recent finding [14] , which promoted the hypothesis that specific antibody against virus might be associated with disease progression in COVID-19. In this retrospective cohort study, IgG and IgM against SARS-CoV-2 in severe/critical patients with COVID-19 were profiled, and relationship between antibody titers AGING and outcomes was also assessed. ./cache/cord-341976-yts6pzn3.txt ./txt/cord-341976-yts6pzn3.txt