id author title date pages extension mime words sentences flesch summary cache txt cord-339951-how9cmw8 Zhou, Yaqing Clinical and Autoimmune Characteristics of Severe and Critical Cases of COVID‐19 2020-05-14 .txt text/plain 2580 157 50 The clinical, autoimmune, and laboratory characteristics of 21 patients who had laboratory‐confirmed severe and critical cases of coronavirus disease 2019 (COVID‐19) from the intensive care unit of the Huangshi Central Hospital, Hubei Province, China, were investigated. According to the sixth edition of Guidance for Corona Virus Disease 2019: Prevention, Control, Diagnosis and Management, issued by China's National Health Commission, the diagnostic criteria for the clinical classification of COVID-19 are as follows: (i) mild-clinical symptoms are mild and no pneumonia manifestation can be found on imaging; (ii) ordinary-symptoms such as fever and respiratory tract symptoms and pneumonia manifestations can be seen on imaging; (iii) severe-any of the following: respiratory distress, respiratory rate (RR) ≥30 breaths/min, oxygen saturation <93% at rest, arterial partial pressure of oxygen (PaO 2 )/oxygen concentration (FIO 2 ) ≤300 mmHg (1 mmHg = 0.133 kPa), or >50% lesion progression within 24-48 hours on pulmonary imaging; and (iv) critical-any of the following: respiratory failure in which mechanical ventilation is required, shock occurs, or complications with another organ failure that require monitoring and treatment in the ICU. In this single-center and retrospective study, we have reported on the clinical and laboratory characteristics of 8 severe and 13 critical cases of SARS-CoV-2 in Huangshi, Hubei Province, China. ./cache/cord-339951-how9cmw8.txt ./txt/cord-339951-how9cmw8.txt