id author title date pages extension mime words sentences flesch summary cache txt cord-339669-p61j2caf Monzani, Alice QTc evaluation in COVID‐19 patients treated with chloroquine/hydroxychloroquine 2020-05-18 .txt text/plain 1244 63 44 In late December 2019, a cluster of pneumonia cases caused by a novel coronavirus occurred in Wuhan, China and has spread rapidly initially throughout Europe and later USA (1). In late December 2019, a cluster of pneumonia cases caused by a novel coronavirus occurred in Wuhan, China, and has spread rapidly initially throughout Europe and later in the United States. Despite poor real clinical evidence of unequivocal beneficial effect of chloroquine/hydroxychloroquine (CQ/HCQ), the absence of an effective COVID-19 treatment and the social pressure raised the demand of these drugs for its compassionate use, both in hospital and outpatient settings. 10 High-dosed HCQ showed promising potential effect in reducing SARS-CoV-2 viral load in COVID-19 patients with enhanced effects in combination with azithromycin or several antiviral drugs. In so forth, we believe that is probably time to have prospective clinical trials that will evaluate the safety and efficacy of HCQ during treatment of COVID-infected patients. ./cache/cord-339669-p61j2caf.txt ./txt/cord-339669-p61j2caf.txt