id author title date pages extension mime words sentences flesch summary cache txt cord-338798-xsun927w Ciorba, Andrea Ototoxicity prevention during the SARS-CoV-2 (Covid-19) emergency 2020-10-17 .txt text/plain 499 37 42 • To remind the risk of ototoxicity when using chloroquine and hydroxychloroquine, in particular as prophylactic agents against SARS-CoV-2, during the pandemic. • Healthy subjects taking chloroquine and hydroxychloroquine as prophylactic agent against SARS-CoV-2, during the pandemic, should be screened periodically, at least by OAEs. eventually adequate treatment is established (3) (4) (5) . Pure tone audiometry represents the main instrument for the identification and classification of hearing impairment; however, Otoacoustic Emissions (OAEs) are reported to be very sensitive in evaluating early manifestations of cochlear damages (6), as ototoxic drugs typically affect primarily outer hair cells (1, (3) (4) (5) . Therefore, healthy subjects taking chloroquine and hydroxychloroquine as prophylactic agent against SARS-CoV-2, during the pandemic, should be screened periodically, at least by OAEs. Clearly, even without a fatal condition, it is important to avoid the onset of ototoxic manifestations, especially when chloroquine and hydroxychloroquine are administered with a prophylaxis intent. ./cache/cord-338798-xsun927w.txt ./txt/cord-338798-xsun927w.txt