id author title date pages extension mime words sentences flesch summary cache txt cord-337789-pabaoiqs Oprinca, George-Călin Postmortem examination of three SARS-CoV-2-positive autopsies including histopathologic and immunohistochemical analysis 2020-08-27 .txt text/plain 4995 282 47 This paper describes three autopsy cases with postmortem diagnosis of SARS-CoV-2 infection, with detailed macroscopic examination as well as advanced microscopic studies of organ tissues collected using hematoxylin-eosin stains and immunohistochemical markers. Microscopic evaluation revealed viral cytopathic effect of type II pneumocytes with a couple of cells that presented cytoplasmic and nuclear inclusions and who tend to form clusters mimicking multinucleated giant cells. This paper describes three autopsy cases with unknown cause of death, with full macroscopic examination as well as histopathologic and immunohistochemical analysis of collected organ tissues, including the lung from which reverse transcription polymerase chain reaction (rt-PCR) tests were made to determine SARS-CoV-2 infection. Microscopic examination of the pulmonary tissue revealed large areas of alveolar damage with destruction of the alveolar wall lining and intra-alveolar septa, marked vascular congestion, accompanied by intra-alveolar hemorrhage. ./cache/cord-337789-pabaoiqs.txt ./txt/cord-337789-pabaoiqs.txt