id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-337436-3xzgv370	Khider, Lina	Curative anticoagulation prevents endothelial lesion in COVID‐19 patients	2020-06-18		.txt	text/plain	1774	110	44	METHODS: Study analyzed clinical and biological profiles of patients with suspected COVID‐19 infection at admission, including hemostasis tests and quantification of circulating endothelial cells (CECs). Circulating endothelial cells (CECs) are considered as relevant markers of Accepted Article 1 endothelial lesion or dysfunction (12) and were used to explore the potential vascular dysfunction 2 in COVID-19 patients. Among COVID-19 positive patients, 64% were above this threshold, suggesting a SARSThe originality of this study was to evidence an endothelial lesion during SARS-CoV-2 infection, 3 as witnessed by increased levels of CECs. Second, we show that this endothelial damage is 4 thwarted by curative anticoagulation. Interestingly, patients enrolled while they were treated with 6 curative anticoagulation had a significantly lower level of CECs, especially in the hypertensive 7 population treated with ACEi or ARBs. Increased mortality and/or morbidity of COVID-19 in 8 patients with hypertension has been described in China (3).	./cache/cord-337436-3xzgv370.txt	./txt/cord-337436-3xzgv370.txt