id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-336720-2bf3xzni	Zhen, Wei	Comparison of Four Molecular In Vitro Diagnostic Assays for the Detection of SARS-CoV-2 in Nasopharyngeal Specimens	2020-04-22		.txt	text/plain	3045	205	60	In the present study, we have evaluated the analytical sensitivity and clinical performance of four SARS-CoV-2 molecular diagnostic assays granted Emergency Use Authorization by the FDA using nasopharyngeal swabs from symptomatic patients. The LoD established by percent positive rate ranged from 1,000 copies/mL by both the GenMark and the 172 modified CDC assays to 50 copies/mL by the DiaSorin Molecular assay ( Table 2) . Overall turn-around time assessment, from sample to results, showed DiaSorin Molecular with the least 224 overall turn-around time to results, followed by GenMark, modified CDC assay and Hologic with the 225 greatest overall time ( Table 5) . DiaSorin 268 Molecular and GenMark showed 100% specificity, while Hologic and the CDC assay initially had two and 269 one discordant results, respectively. For workflow, TAT, and 298 ease of use, the three sample-to-answer platforms (DiaSorin Molecular, Hologic, GenMark) out-299 performed the modified CDC assay, which is a manual assay requiring many steps, specialized personnel, 300	./cache/cord-336720-2bf3xzni.txt	./txt/cord-336720-2bf3xzni.txt