id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-335599-98ovzui5	Raony, Ícaro	Retinal outcomes of COVID-19: possible role of CD147 and cytokine storm in infected patients with diabetes mellitus	2020-06-25		.txt	text/plain	1198	54	42	title: Retinal outcomes of COVID-19: possible role of CD147 and cytokine storm in infected patients with diabetes mellitus Notwithstanding this, it was not discussed whether the patients already presenting changes in the retina before infection with COVID-19, or even if there was any systemic disease (e.g. type 2 diabetes mellitus) that could also be associated with retinal lesions. Thus, it is possible that CD147, by mediating the breakdown of the blood-retinal barrier in a hyperglycemic context, may facilitate the invasion of retinal cells by SARS-CoV-2 in people with DM, which deserves to be investigated by future studies with animal models and humans. The reverse is also possible, with COVID-19 being able to precipitate or worsen retinal lesions present in patients with DM in the short or long term, either by direct effects of retinal SARS-CoV-2 infection, or by the indirect effects of the cytokine storm associated with COVID-19.	./cache/cord-335599-98ovzui5.txt	./txt/cord-335599-98ovzui5.txt