id author title date pages extension mime words sentences flesch summary cache txt cord-335492-od3c25qg UGUREL, Osman Mutluhan An updated analysis of variations in SARS-CoV-2 genome 2020-06-21 .txt text/plain 4971 273 57 In this study; we have used these data to analyse the mutations on SARS-CoV-2 genome using a software based on multiple sequence alignment (Strategy Based Local Alignment Tool: ODOTool) that have been originally developed for bacterial SNP determination in our studies. Now, we targeted to analyse the mutations that have emerged in at least 10% of SARS-CoV-2 genomes in all 30366 sequences submitted in GISAID by May 20th, 2020 using the ODOTool in terms of date and location they occurred, the relationship with each other and their effect on the primary protein structure. Despite the Strategy Based Local Alignment Tool (ODOTool) used in this study was originally developed by our group for bacterial single nucleotide polymorphism (SNP) determination, it was reasonable to test the abilities of the tool using a different dataset with the emergence of SARS-CoV-2 causing COVID-19 pandemic and this is applied in the present study to analyse variations in viral genome. ./cache/cord-335492-od3c25qg.txt ./txt/cord-335492-od3c25qg.txt