id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-335446-8l1vfsbc	Liao, M.	The landscape of lung bronchoalveolar immune cells in COVID-19 revealed by single-cell RNA sequencing	2020-02-26		.txt	text/plain	4710	311	55	Here, we comprehensively characterized the lung immune microenvironment with the bronchoalveolar lavage fluid (BALF) from 3 severe and 3 mild COVID-19 patients and 8 previously reported healthy lung controls through single-cell RNA sequence (scRNA-seq) combined with TCR-seq. To characterize the immune microenvironment of the SARS-CoV-2-infected lung, we performed scRNA-seq analysis of single cells in the lung BALF (37, 820 cells) using the 10X Genomics platform, from 3 of recovered mild cases and 3 of severe cases ( Figure 1A , Table 1 ). Our data indicated that the monocytes are recruited from circulation (FCN1 + ) to the lung to fuel the inflammation during severe diseases, and some monocytes may further go through the differentiation process into the SPP1 + populations and eventually the FABP4 + AMs. robust and early T cell response played crucial roles in viral clearance during acute respiratory infections [14] .	./cache/cord-335446-8l1vfsbc.txt	./txt/cord-335446-8l1vfsbc.txt