id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-333654-8rg99di5	Pillai, Presaad	COVID-19 AND MAJOR ORGAN THROMBOEMBOLISM: MANIFESTATIONS IN NEUROVASCULAR AND CARDIOVASCULAR SYSTEMS.	2020-10-24		.txt	text/plain	4128	210	39	The disease, caused by severe acute respiratory syndrome coronavirus 2(SARS-CoV-2), has to date been responsible for more than 800,000 deaths globally, economic upheaval and significant lifestyle changes. 5, 6, 7 However, more recently immune mediated thrombosis has been a consistent finding in a significant number of patients with of Covid-19 and understanding its pathophysiological mechanisms and impact on morbidity and mortality in COVID-19 may open new avenues in disease prognostication and management. Thus, D-dimer level could potentially be an early and helpful marker to improve the management of COVID-19 and point clinicians to the possibility of silent thrombosis occurring in the pre-symptomatic stage which might dictate the natural history, progression and severity of the disease in a manner that has not been seen in previous coronavirus infections. Other significant risk factors, excluding raised D-dimer and CRP, that were associated with a high mortality rate for these patients with NVD, were comorbidities, age and increased severity of COVID-19 infection.	./cache/cord-333654-8rg99di5.txt	./txt/cord-333654-8rg99di5.txt