id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-333018-2h8y118z	Sun, Xingxing	Safety Considerations for Neuraxial Anaesthesia in Parturients with COVID-19	2020-05-14		.txt	text/plain	649	43	42	To decide the mode of anaesthesia for parturients with COVID-19, one should evaluate neurological symptoms in addition to respiratory symptoms. Angiotensin-converting enzyme 2 (ACE2) is the functional receptor for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); 7 it is expressed in the cell membrane of various tissues and organs including lung, small intestine, and brain. When deciding on anaesthetic strategy for patients with COVID-19, we think that one should consider the possible deleterious effects on the nervous system by neuraxial anaesthesia. For patients with apparent central or peripheral nervous system symptoms, although direct evidence is still lacking, general anaesthesia might be an acceptable alternative. However, general anaesthesia can impair the blood-brain barrier 10 , which might facilitate the invasion of SARS-CoV-2 into the central nervous system. Emergency Caesarean delivery in a patient with confirmed coronavirus disease 2019 under spinal anaesthesia	./cache/cord-333018-2h8y118z.txt	./txt/cord-333018-2h8y118z.txt