id author title date pages extension mime words sentences flesch summary cache txt cord-329473-dtlwjndn Guo, Ao-Xiang The clinical characteristics and mortal causes analysis of COVID-19 death patients 2020-04-15 .txt text/plain 3279 240 63 Therefore, we supposed that the expression of ACE2 and TMPRSS2 in human tissues could be used to explain the clinical characteristics of COVID-19 patients, including coexisting disorders, direct causes of death and initial symptoms. Our results also proved that coexisting disorders of hypertension and heart disease and initial symptoms of dyspnea were significantly higher in death patients, which was consistent with the one previous study [7] . While that ACE2 was highly expressed in heart may be related with the attack of SARS-CoV-2 in heart, which may lead to the initial symptoms of palpitate and chest tightness in some patients, and the direct causes of death including circulatory failure, heart disease and cardiac arrest. The expression of the SARS-CoV-2 targets in these important organs such as lung, heart, liver and kidney may help to explain the clinical characteristics of death patients. ./cache/cord-329473-dtlwjndn.txt ./txt/cord-329473-dtlwjndn.txt