id author title date pages extension mime words sentences flesch summary cache txt cord-328557-f6o1aynz Samad, Abdus Designing a multi-epitope vaccine against SARS-CoV-2: an immunoinformatics approach 2020-07-17 .txt text/plain 7593 423 50 So, targeting S-protein can provide an immunogenic response in the human host, and has been chosen for designing a multi-epitopes vaccine candidate against the SARS-CoV-2. For the prediction of CTLs epitope, the sequence of the selected protein was submitted into the NetCTL v1.2 server available at http://www.cbs.dtu. For this purpose, we submitted the refined vaccine model as ligand and TLR4 protein as immunological receptor into the ClusPro v2.0 server, available at https://cluspro.bu.edu/, for molecular docking (Kozakov et al., 2017) . Due to the high number of potential epitopes, we selected the top four CTL epitopes for the final vaccine construction based on the antigenicity score (Table 1) . Likewise, we considered the top four HTL epitopes for incorporating into the final vaccine construct based on the antigenic score (Table 2) . In this study, we designed an epitope-based vaccine that could provide a strong immune response against SARS-CoV-2, thereby, preventing the COVID-19 pandemic. ./cache/cord-328557-f6o1aynz.txt ./txt/cord-328557-f6o1aynz.txt