id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-328262-hw8swbt5	O’Neill, Luke A. J.	BCG-induced trained immunity: can it offer protection against COVID-19?	2020-05-11		.txt	text/plain	2177	102	42	Bacillus Calmette–Guérin (BCG) vaccination has been reported to decrease susceptibility to respiratory tract infections, an effect proposed to be mediated by the general long-term boosting of innate immune mechanisms, also termed trained immunity. This effect was mediated by peritoneal macrophages 10 Bacillus Calmette-Guérin (BCG) vaccination has been reported to decrease susceptibility to respiratory tract infections, an effect proposed to be mediated by the general long-term boosting of innate immune mechanisms, also termed trained immunity. Here, we discuss the non-specific beneficial effects of BCG against viral infections and whether this vaccine may afford protection to COVID-19. Here, we discuss the non-specific beneficial effects of BCG against viral infections and whether this vaccine may afford protection to COVID-19. BCG vaccination protects against experimental viral infection in humans through the induction of cytokines associated with trained immunity	./cache/cord-328262-hw8swbt5.txt	./txt/cord-328262-hw8swbt5.txt