id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-327263-d5mmeu96	Christoff, A. P.	Swab pooling for large-scale RT-qPCR screening of SARS-CoV-2	2020-09-05		.txt	text/plain	4134	258	49	Therefore, pooling strategies that minimize sample dilution, loss of sensitivity, and laboratory overload are needed to allow reliable and large-scale screenings of SARS-CoV-2. . https://doi.org/10.1101/2020.09.03.20187732 doi: medRxiv preprint detect clear differences due to dilution alone, with point estimates from 0.43 to 0.61 Cq. In practice, observational data from 246 positive patients generated point estimates of mean Cq differences between individual tests and their corresponding pools ranging from 0.1 to 2.09 Cq. While such values are hardly significant in terms of analytical sensitivity, the expected counterparts for traditional pooling would range from 3.3 to 5 Cq under optimal amplification conditions. . https://doi.org/10.1101/2020.09.03.20187732 doi: medRxiv preprint of diagnostic samples for SARS-CoV-2 can also perform swab pool analysis using the same detection methods and infrastructure already in use. . https://doi.org/10.1101/2020.09.03.20187732 doi: medRxiv preprint CONCLUSION Pool testing is a major alternative for large-scale screening of SARS-CoV-2 in low prevalence populations.	./cache/cord-327263-d5mmeu96.txt	./txt/cord-327263-d5mmeu96.txt