id author title date pages extension mime words sentences flesch summary cache txt cord-326730-aprb819p Perkmann, T. Side by side comparison of three fully automated SARS-CoV-2 antibody assays with a focus on specificity 2020-06-05 .txt text/plain 3232 236 53 Methods: We included a total of 1,154 specimens from pre-COVID-19 times and 65 samples from COVID-19 patients ([≥]14 days after symptom onset) to evaluate the test performance of SARS-CoV-2 serological assays by Abbott, Roche, and DiaSorin. Conclusion: We find diagnostically relevant differences in specificities for the anti-SARS-CoV-2 antibody assays by Abbott, Roche, and DiaSorin that have a significant impact on the positive predictability of these tests. The present evaluation aims to compare three of these test systems manufactured by Abbott (11), DiaSorin (12), and Roche (13) , with particular emphasis on specificity, which is crucial for an adequate positive predictive value given the current low seroprevalence worldwide. We find diagnostically relevant differences in specificities for the anti-SARS-CoV-2 antibody assays by Abbott, Roche, and DiaSorin that have a significant impact on the positive predictability of these tests. ./cache/cord-326730-aprb819p.txt ./txt/cord-326730-aprb819p.txt