id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-326581-31trqhi1	Ihling, Christian	Mass Spectrometric Identification of SARS-CoV-2 Proteins from Gargle Solution Samples of COVID-19 Patients	2020-06-22		.txt	text/plain	1147	81	54	title: Mass Spectrometric Identification of SARS-CoV-2 Proteins from Gargle Solution Samples of COVID-19 Patients We developed a simple, MS-based method to specifically detect SARS-CoV-2 proteins from gargle solution samples of COVID-19 patients. 2 On the basis of the prospective goals of this coalition, the aim of this "proof-of-principle" study is to highlight the potential of MS in identifying SARS-CoV-2 proteins, even from highly diluted samples, such as gargle solutions of COVID-19 patients. All samples had been classified as SARS-CoV-2-positive by three reverse-transcription and quantitative polymerase chain reaction (RT-qPCR) analyses identifying E-, S-, and N-gene RNAs. For protein precipitation, 1 mL of acetone (−20°C) was added to 750 μL of gargle solution and stored overnight at −20°C. We present a protein MS-based method to specifically detect SARS-CoV-2 virus proteins from highly diluted gargle solutions of COVID-19 patients. Using this approach, we were able to identify peptides originating from SARS-CoV-2 nucleoprotein in gargle solution samples.	./cache/cord-326581-31trqhi1.txt	./txt/cord-326581-31trqhi1.txt